Page last updated: 2024-11-07

prednisone and Precursor T-Cell Lymphoblastic Leukemia-Lymphoma

prednisone has been researched along with Precursor T-Cell Lymphoblastic Leukemia-Lymphoma in 38 studies

Prednisone: A synthetic anti-inflammatory glucocorticoid derived from CORTISONE. It is biologically inert and converted to PREDNISOLONE in the liver.
prednisone : A synthetic glucocorticoid drug that is particularly effective as an immunosuppressant, and affects virtually all of the immune system. Prednisone is a prodrug that is converted by the liver into prednisolone (a beta-hydroxy group instead of the oxo group at position 11), which is the active drug and also a steroid.

Precursor T-Cell Lymphoblastic Leukemia-Lymphoma: A leukemia/lymphoma found predominately in children and young adults and characterized LYMPHADENOPATHY and THYMUS GLAND involvement. It most frequently presents as a lymphoma, but a leukemic progression in the bone marrow is common.

Research Excerpts

ExcerptRelevanceReference
" We encountered severe autonomic neuropathy and cholestasis in a child receiving vincristine, after the introduction of piperacillin-tazobactam."3.78A case of severe toxicity during coadministration of vincristine and piperacillin: are drug transporters involved in vincristine hypersensitivity and drug-drug interactions? ( Andres, CR; Benz-de Bretagne, I; Gendrot, C; Jonville-Bera, AP; Jourdain, A; Le Guellec, C; Tarfaoui, N, 2012)
"Induction therapy for childhood acute lymphoblastic leukemia (ALL) traditionally includes prednisone; yet, dexamethasone may have higher antileukemic potency, leading to fewer relapses and improved survival."2.82Dexamethasone vs prednisone in induction treatment of pediatric ALL: results of the randomized trial AIEOP-BFM ALL 2000. ( Aricò, M; Attarbaschi, A; Barisone, E; Bartram, CR; Basso, G; Beier, R; Biondi, A; Caruso, R; Cazzaniga, G; Conter, V; Greiner, J; Harbott, J; Kremens, B; Kulozik, AE; Lo Nigro, L; Locatelli, F; Mann, G; Möricke, A; Niggli, F; Parasole, R; Ratei, R; Rössig, C; Schrappe, M; Silvestri, D; Stanulla, M; Valsecchi, MG; von Stackelberg, A; Zimmermann, M, 2016)
"Besides, the PLK4 expression in childhood ALL patients was also determined at day 15 after the initiation of induction therapy (D15)."1.91Polo-like Kinase 4: the Variation During Therapy and its Relation to Treatment Response and Prognostic Risk Stratification in Childhood Acute Lymphoblastic Leukemia Patients. ( Xu, J; Zhao, L, 2023)
"The BFM studies for relapsed childhood acute lymphoblastic leukemia (ALL) were started in 1983, at a time when cure rates for ALL were still lower and the number of children with ALL relapse equaled about the number of children with newly diagnosed neuroblastoma."1.39ALL-REZ BFM--the consecutive trials for children with relapsed acute lymphoblastic leukemia. ( Eckert, C; Henze, G; v Stackelberg, A, 2013)
"Risperidone is an effective short-term pharmacologic agent for controlling steroid-related psychiatric adverse effects when cessation or dose reduction of steroid therapy is not an option."1.36Concurrent treatment of steroid-related mood and psychotic symptoms with risperidone. ( Dahl, G; Shaw, RJ; Tzuang, D; Ularntinon, S, 2010)
"We retrospectively estimated the minimal residual disease in the bone marrow (BM) and the testis by detection of clone-specific T-cell receptor rearrangement of leukemic cells."1.35Detection of submicroscopic disease in the bone marrow and unaffected testis of a child with T-cell acute lymphoblastic leukemia who experienced "isolated" testicular relapse. ( Arima, K; Hasegawa, D; Hori, T; Hosoya, R; Imamura, T; Kato, I; Kitagawa, Y; Manabe, A; Ogawa, C; Takahashi, H; Takusagawa, A; Tsurusawa, M, 2009)

Research

Studies (38)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (5.26)29.6817
2010's26 (68.42)24.3611
2020's10 (26.32)2.80

Authors

AuthorsStudies
Kośmider, K1
Karska, K1
Kozakiewicz, A1
Lejman, M1
Zawitkowska, J1
Xu, J1
Zhao, L1
Wu, SY1
Chu, XR1
Ji, Q1
Lin, XC1
Bai, ZJ1
Li, JQ1
Pan, J1
Chen, ZX1
Hu, SY1
Rausch, CR1
Jabbour, EJ1
Kantarjian, HM1
Kadia, TM1
Montoro, J1
Chorão, P1
Quintero, A1
Roca, J1
Guerreiro, M1
Balaguer-Roselló, A1
Dunsmore, KP1
Winter, SS1
Devidas, M2
Wood, BL1
Esiashvili, N1
Chen, Z1
Eisenberg, N1
Briegel, N1
Hayashi, RJ1
Gastier-Foster, JM1
Carroll, AJ1
Heerema, NA1
Asselin, BL1
Rabin, KR1
Zweidler-Mckay, PA1
Raetz, EA1
Loh, ML1
Schultz, KR1
Winick, NJ1
Carroll, WL1
Hunger, SP1
Dai, Q1
Zhang, G1
Yang, H1
Wang, Y1
Ye, L1
Peng, L1
Shi, R1
Guo, S1
He, J1
Jiang, Y1
Yadav, SP1
Wadhwa, T1
Thakkar, D1
Kapoor, R1
Rastogi, N1
Sarma, S1
Morita, K1
Jain, N1
Kantarjian, H1
Takahashi, K1
Fang, H1
Konopleva, M1
El Hussein, S1
Wang, F1
Short, NJ1
Maiti, A1
Sasaki, K1
Garcia-Manero, G1
Konoplev, S1
Ravandi, F1
Khoury, JD1
Jabbour, E1
Andrieu, GP1
Kohn, M1
Simonin, M1
Smith, CL1
Cieslak, A1
Dourthe, MÉ1
Charbonnier, G1
Graux, C1
Huguet, F1
Lhéritier, V1
Dombret, H1
Spicuglia, S1
Rousselot, P1
Boissel, N1
Asnafi, V1
Landmann, E1
Burkhardt, B1
Zimmermann, M6
Meyer, U1
Woessmann, W1
Klapper, W1
Wrobel, G1
Rosolen, A1
Pillon, M1
Escherich, G1
Attarbaschi, A4
Beishuizen, A1
Mellgren, K1
Wynn, R1
Ratei, R4
Plesa, A1
Schrappe, M7
Reiter, A1
Bergeron, C1
Patte, C1
Bertrand, Y1
Valliyammai, N1
Nancy, NK1
Sagar, TG1
Rajkumar, T1
Paganin, M1
Grillo, MF1
Silvestri, D2
Scapinello, G1
Buldini, B1
Cazzaniga, G2
Biondi, A2
Valsecchi, MG2
Conter, V2
Te Kronnie, G1
Basso, G2
Fuhrmann, S1
Schabath, R2
Möricke, A4
Kunz, JB2
Kulozik, AE4
Ludwig, WD3
Karawajew, L2
Szarzyńska-Zawadzka, B1
Sędek, Ł1
Kosmalska, M1
Zdon, K1
Biecek, P1
Bandapalli, OR2
Kraszewska-Hamilton, M1
Jaksik, R1
Drobna, M1
Kowalczyk, JR1
Szczepański, T1
Van Vlierberghe, P1
Witt, M1
Dawidowska, M1
Henze, G1
v Stackelberg, A1
Eckert, C1
Hayase, E1
Sugita, J1
Fujimoto, K1
Ebata, K1
Yamakawa, T1
Yoshida, M2
Takemura, R1
Iwasaki, J1
Takahashi, S1
Shiratori, S1
Kondo, T1
Tanaka, J1
Teshima, T1
Demlova, R1
Mrkvicova, M1
Sterba, J1
Bernatikova, H1
Stary, J1
Sukova, M1
Mikuskova, A1
Chocholova, A1
Mladosievicova, B1
Soltysova, A1
Behulova, D1
Pilatova, K1
Zdrazilova-Dubska, L1
Valik, D1
Hastings, C1
Gaynon, PS1
Nachman, JB1
Sather, HN1
Lu, X1
Seibel, NL1
Hong, C1
Tang, KS1
Villegas, M1
Tan, PL1
Stanulla, M3
Mann, G2
Locatelli, F1
Niggli, F2
Aricò, M1
Bartram, CR1
Beier, R2
Lo Nigro, L1
Kremens, B1
Greiner, J1
Parasole, R1
Harbott, J1
Caruso, R1
von Stackelberg, A1
Barisone, E1
Rössig, C1
Cai, JY1
Xue, HL1
Chen, J1
Shen, SH1
Pan, C1
Wang, X1
Zhou, M1
Tang, YJ1
Gao, YJ1
Wang, JM1
Tang, JY1
Grimes, A1
Mirkheshti, N1
Chatterjee, B1
Tomlinson, G1
Assanasen, C1
Nascimbeni, C1
Chantepie, S1
Brugiere, C1
Comoz, F1
Salaun, V1
Verneuil, L1
Deenik, W1
Beverloo, HB1
van der Poel-van de Luytgaarde, SC1
Wattel, MM1
van Esser, JW1
Valk, PJ1
Cornelissen, JJ1
Arima, K1
Hasegawa, D1
Ogawa, C1
Kato, I1
Imamura, T1
Takusagawa, A1
Takahashi, H2
Kitagawa, Y1
Hori, T1
Tsurusawa, M1
Manabe, A2
Hosoya, R1
Pisecker, M1
Inthal, A1
Janousek, D1
Dworzak, M1
Pötschger, U1
Ullmann, R1
Gadner, H1
Haas, OA1
Panzer-Grümayer, R1
Strehl, S1
Losa Frías, V1
Martín-Sacristán Martín, B1
Díaz Conejo, R1
Ramos Corral, R1
Velasco Arribas, MR1
Cai, Y1
Sun, XF1
Yan, SL1
Zhen, ZJ1
Xia, Y1
Ling, JY1
Ularntinon, S1
Tzuang, D1
Dahl, G1
Shaw, RJ1
Chen, X1
Zhang, Y1
Li, Y1
Lei, P1
Zhai, Y1
Liu, L1
Zuurbier, L1
Homminga, I1
Calvert, V1
te Winkel, ML1
Buijs-Gladdines, JG1
Kooi, C1
Smits, WK1
Sonneveld, E1
Veerman, AJ1
Kamps, WA1
Horstmann, M1
Petricoin, EF1
Pieters, R1
Meijerink, JP1
Kox, C1
Leible, S1
Koehler, R1
Tolle, G1
Breit, S1
Muckenthaler, MU1
Niino, D1
Ohsaki, K1
Arakawa, F1
Watanabe, J1
Kimura, Y1
Kiyasu, J1
Takeuchi, M1
Miyoshi, H1
Sugita, Y1
Ohshima, K1
Okamura, T1
Inukai, T1
Kiyokawa, N1
Campana, D1
Coustan-Smith, E1
Kikuchi, A1
Kobayashi, M1
Koh, K1
Kumagai, M1
Ikuta, K1
Hayashi, Y1
Tsuchida, M1
Sugita, K1
Ohara, A1
Lauten, M1
Meissner, B1
Odenwald, E1
Niemeyer, C1
Riehm, H1
Le Guellec, C1
Benz-de Bretagne, I1
Jonville-Bera, AP1
Tarfaoui, N1
Andres, CR1
Gendrot, C1
Jourdain, A1

Clinical Trials (4)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Intensified Methotrexate, Nelarabine (Compound 506U78) and Augmented BFM Therapy for Children and Young Adults With Newly Diagnosed T-cell Acute Lymphoblastic Leukemia (ALL) or T-cell Lymphoblastic Lymphoma[NCT00408005]Phase 31,895 participants (Actual)Interventional2007-01-22Active, not recruiting
Treatment Protocol for T-Cell and B-Precursor Cell Lymphoblastic Lymphoma of the European Inter-group Co-operation on Childhood Non-Hodgkin-Lymphoma (EICNHL)[NCT00275106]Phase 3600 participants (Anticipated)Interventional2004-09-30Terminated (stopped due to Withdrawn due to an excess of toxic deaths)
ALL-BFM 2000 Multi-Center Study for the Treatment of Children and Adolescents With Acute Lymphoblastic Leukemia[NCT00430118]Phase 34,559 participants (Actual)Interventional2000-07-31Completed
AIEOP LLA 2000 Multicenter Study for the Diagnosis and Treatment of Childhood Acute Lymphoblastic Leukemia[NCT00613457]Phase 32,039 participants (Actual)Interventional2000-09-30Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Disease-free Survival (DFS) for Randomized Methotrexate T-ALL Cohort (Arm I + Arm II vs. Arm III + Arm IV)

Disease Free Probability where DFS time is defined as time from randomization end of induction to first event (relapse, second malignant neoplasm, death) or date of last contact for patients who are event-free. (NCT00408005)
Timeframe: 4 years from randomization at the end of induction

Interventionpercent probability (Number)
ARM I and ARM II (Combination Chemotherapy)91.45
ARM III and ARM IV (Combination Chemotherapy)85.78

Disease-free Survival (DFS) for Randomized Methotrexate T-ALL Cohort (Arm I vs. Arm II vs. Arm III vs. Arm IV)

Disease-free survival defined as time from randomization end of induction to first event (relapse, second malignant neoplasm, remission death) or date of last contact for those who are event-free. (NCT00408005)
Timeframe: 4 years from randomization at the end of induction

Interventionpercent probability (Number)
ARM I (Combination Chemotherapy)91.76
ARM II (Combination Chemotherapy)90.53
ARM III (Combination Chemotherapy)86.06
ARM IV (Combination Chemotherapy)84.89

Disease-free Survival (DFS) for Randomized Nelarabine T-ALL Cohort (Arm I + Arm III vs. Arm II + Arm IV)

Disease Free Probability where DFS time is defined as time from randomization end of induction to first event (relapse, second malignant neoplasm, death) or date of last contact for patients who are event (NCT00408005)
Timeframe: 4 years from randomization at the end of induction

Interventionpercent probability (Number)
ARM I and ARM III (Combination Chemotherapy)82.96
ARM II and ARM IV (Combination Chemotherapy)88.30

Disease-free Survival (DFS) for Randomized Nelarabine T-ALL Cohort (Arm I vs. Arm II vs. Arm III vs. Arm IV)

Disease Free Probability where DFS time is defined as time from randomization end of induction to first event (relapse, second malignant neoplasm, death) or date of last contact for patients who are event-free. (NCT00408005)
Timeframe: 4 years from randomization at the end of induction

Interventionpercent probability (Number)
ARM I (Combination Chemotherapy)89.01
ARM II (Combination Chemotherapy)90.53
ARM III (Combination Chemotherapy)78.07
ARM IV (Combination Chemotherapy)86.46

Cumulative Incidence of CNS Relapse for T-ALL by Risk Group

Cumulative incidence of CNS relapse adjusting for DFS events, was calculated using the method Gray et. al. High risk patients receive cranial radiation and low risk patients receive no cranial radiation. (NCT00408005)
Timeframe: 4 years from randomization at the end of induction

,
Interventionpercent probability (Number)
Intermediate RiskHigh Risk
ARM II (Combination Chemotherapy)1.080
ARM IV (Combination Chemotherapy)0.853.45

Cumulative Incidence of CNS Relapse for T-ALL by Risk Group

Cumulative incidence of CNS relapse adjusting for DFS events, was calculated using the method Gray et. al. High risk patients receive cranial radiation and low risk patients receive no cranial radiation. (NCT00408005)
Timeframe: 4 years from randomization at the end of induction

,
Interventionpercent probability (Number)
Low RiskIntermediate RiskHigh Risk
ARM I (Combination Chemotherapy)1.851.163.64
ARM III (Combination Chemotherapy)1.929.16.52

Disease-free Survival (DFS) for T-cell Lymphoblastic Lymphoma (T-LLy) Cohort

Disease Free Probability where DFS time is defined as time from randomization end of induction to first event (relapse, second malignant neoplasm, death) or date of last contact for patients who are event-free. (NCT00408005)
Timeframe: 4 years from end of induction

Interventionpercent probability (Number)
High RiskInduction Failure
ARM II (Combination Chemotherapy)85.0100

Disease-free Survival (DFS) for T-cell Lymphoblastic Lymphoma (T-LLy) Cohort

Disease Free Probability where DFS time is defined as time from randomization end of induction to first event (relapse, second malignant neoplasm, death) or date of last contact for patients who are event-free. (NCT00408005)
Timeframe: 4 years from end of induction

Interventionpercent probability (Number)
Standard RiskHigh Risk
ARM I (Combination Chemotherapy)87.485.1

Reviews

2 reviews available for prednisone and Precursor T-Cell Lymphoblastic Leukemia-Lymphoma

ArticleYear
Overcoming Steroid Resistance in Pediatric Acute Lymphoblastic Leukemia-The State-of-the-Art Knowledge and Future Prospects.
    International journal of molecular sciences, 2022, Mar-30, Volume: 23, Issue:7

    Topics: Extracellular Signal-Regulated MAP Kinases; Glucocorticoids; Humans; Precursor Cell Lymphoblastic Le

2022
[Posterior reversible encephalopathy syndrome following paralytic ileus caused by vincristine in a patient with T cell lymphoblastic lymphoma].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 2014, Volume: 55, Issue:2

    Topics: Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Doxorubicin; Female; Humans; Induc

2014

Trials

9 trials available for prednisone and Precursor T-Cell Lymphoblastic Leukemia-Lymphoma

ArticleYear
Children's Oncology Group AALL0434: A Phase III Randomized Clinical Trial Testing Nelarabine in Newly Diagnosed T-Cell Acute Lymphoblastic Leukemia.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2020, 10-01, Volume: 38, Issue:28

    Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Arabinonucleosides; Asparaginase; Child;

2020
PRC2 loss of function confers a targetable vulnerability to BET proteins in T-ALL.
    Blood, 2021, 11-11, Volume: 138, Issue:19

    Topics: Adolescent; Adult; Animals; Antineoplastic Agents, Hormonal; Cell Line, Tumor; Epigenesis, Genetic;

2021
Results and conclusions of the European Intergroup EURO-LB02 trial in children and adolescents with lymphoblastic lymphoma.
    Haematologica, 2017, Volume: 102, Issue:12

    Topics: Adolescent; Child; Child, Preschool; Dexamethasone; Europe; Female; Humans; Infant; Male; Precursor

2017
Expression of CD56 defines a distinct subgroup in childhood T-ALL with inferior outcome. Results of the ALL-BFM 2000 trial.
    British journal of haematology, 2018, Volume: 183, Issue:1

    Topics: Antigens, CD34; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; CD13 Antigens; CD56 An

2018
PTEN abnormalities predict poor outcome in children with T-cell acute lymphoblastic leukemia treated according to ALL IC-BFM protocols.
    American journal of hematology, 2019, Volume: 94, Issue:4

    Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Child; Child, Preschool; D

2019
Lineage classification of childhood acute lymphoblastic leukemia according to the EGIL recommendations: results of the ALL-BFM 2000 trial.
    Klinische Padiatrie, 2013, Volume: 225 Suppl 1

    Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Cell Lineage; Child; Child

2013
Increased post-induction intensification improves outcome in children and adolescents with a markedly elevated white blood cell count (≥200 × 10(9) /l) with T cell acute lymphoblastic leukaemia but not B cell disease: a report from the Children's Oncology
    British journal of haematology, 2015, Volume: 168, Issue:4

    Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Child; Child, Preschool; C

2015
Dexamethasone vs prednisone in induction treatment of pediatric ALL: results of the randomized trial AIEOP-BFM ALL 2000.
    Blood, 2016, 04-28, Volume: 127, Issue:17

    Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Combined Modali

2016
Dexamethasone vs prednisone in induction treatment of pediatric ALL: results of the randomized trial AIEOP-BFM ALL 2000.
    Blood, 2016, 04-28, Volume: 127, Issue:17

    Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Combined Modali

2016
Dexamethasone vs prednisone in induction treatment of pediatric ALL: results of the randomized trial AIEOP-BFM ALL 2000.
    Blood, 2016, 04-28, Volume: 127, Issue:17

    Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Combined Modali

2016
Dexamethasone vs prednisone in induction treatment of pediatric ALL: results of the randomized trial AIEOP-BFM ALL 2000.
    Blood, 2016, 04-28, Volume: 127, Issue:17

    Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Combined Modali

2016
Prediction of outcome by early bone marrow response in childhood acute lymphoblastic leukemia treated in the ALL-BFM 95 trial: differential effects in precursor B-cell and T-cell leukemia.
    Haematologica, 2012, Volume: 97, Issue:7

    Topics: Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Biomarkers; Bone Marrow; Child; Child,

2012

Other Studies

27 other studies available for prednisone and Precursor T-Cell Lymphoblastic Leukemia-Lymphoma

ArticleYear
Polo-like Kinase 4: the Variation During Therapy and its Relation to Treatment Response and Prognostic Risk Stratification in Childhood Acute Lymphoblastic Leukemia Patients.
    Journal of pediatric hematology/oncology, 2023, 05-01, Volume: 45, Issue:4

    Topics: Biomarkers; Humans; Precursor B-Cell Lymphoblastic Leukemia-Lymphoma; Precursor Cell Lymphoblastic L

2023
[Expression of
    Zhongguo shi yan xue ye xue za zhi, 2023, Volume: 31, Issue:4

    Topics: Antineoplastic Combined Chemotherapy Protocols; Child; Clinical Relevance; Disease-Free Survival; Hu

2023
Optimizing the use of the hyperCVAD regimen: Clinical vignettes and practical management.
    Cancer, 2020, 03-15, Volume: 126, Issue:6

    Topics: Age Factors; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Brai

2020
Male genital GvHD: a hidden complication following haematopoietic stem cell transplantation.
    British journal of haematology, 2020, Volume: 191, Issue:1

    Topics: Adult; Graft vs Host Disease; Hematopoietic Stem Cell Transplantation; Humans; Male; Penile Diseases

2020
Clinical features and outcome of pediatric acute lymphoblastic leukemia with low peripheral blood blast cell count at diagnosis.
    Medicine, 2021, Jan-29, Volume: 100, Issue:4

    Topics: Adolescent; Antineoplastic Agents, Hormonal; Child; Child, Preschool; Female; Humans; Infant; Infant

2021
COVID-19 reinfection in two children with cancer.
    Pediatric hematology and oncology, 2021, Volume: 38, Issue:4

    Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Carboplatin; Child, Presch

2021
Outcome of T-cell acute lymphoblastic leukemia/lymphoma: Focus on near-ETP phenotype and differential impact of nelarabine.
    American journal of hematology, 2021, 05-01, Volume: 96, Issue:5

    Topics: Adolescent; Adult; Aged; Allografts; Antigens, CD; Antigens, Neoplasm; Antineoplastic Combined Chemo

2021
Study of NOTCH1 and FBXW7 Mutations and Its Prognostic Significance in South Indian T-Cell Acute Lymphoblastic Leukemia.
    Journal of pediatric hematology/oncology, 2018, Volume: 40, Issue:1

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Child; Child, Presc

2018
The presence of mutated and deleted PTEN is associated with an increased risk of relapse in childhood T cell acute lymphoblastic leukaemia treated with AIEOP-BFM ALL protocols.
    British journal of haematology, 2018, Volume: 182, Issue:5

    Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Child; Child, Preschool; D

2018
ALL-REZ BFM--the consecutive trials for children with relapsed acute lymphoblastic leukemia.
    Klinische Padiatrie, 2013, Volume: 225 Suppl 1

    Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Bone Marrow; Child; Combin

2013
Augmenting clinical interpretability of thiopurine methyltransferase laboratory evaluation.
    Oncology, 2014, Volume: 86, Issue:3

    Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Chromatography, High Press

2014
Case report: An unusual presentation of oral acute graft-versus-host-disease in a haploidentical hematopoietic stem cell transplant recipient.
    Oral surgery, oral medicine, oral pathology and oral radiology, 2016, Volume: 121, Issue:3

    Topics: Adolescent; Glucocorticoids; Graft vs Host Disease; Hematopoietic Stem Cell Transplantation; Humans;

2016
[Outcome of childhood T-cell acute lymphoblastic leukemia: a report of 99 cases].
    Zhonghua er ke za zhi = Chinese journal of pediatrics, 2016, Jun-02, Volume: 54, Issue:6

    Topics: Bone Marrow; Child; China; Disease-Free Survival; Flow Cytometry; Humans; Leukocyte Count; Lost to F

2016
Paraneoplastic Galactorrhea in Childhood T-ALL: An Evaluation of Tumor-derived Prolactin.
    Journal of pediatric hematology/oncology, 2017, Volume: 39, Issue:1

    Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Arthralgia; Asparaginase; Chromosome Del

2017
[Cutaneous involvement in T-lymphoblastic lymphoma].
    Annales de dermatologie et de venereologie, 2017, Volume: 144, Issue:4

    Topics: Acute Kidney Injury; Aged; Antineoplastic Combined Chemotherapy Protocols; Bone and Bones; Cyclophos

2017
Rapid complete cytogenetic remission after upfront dasatinib monotherapy in a patient with a NUP214-ABL1-positive T-cell acute lymphoblastic leukemia.
    Leukemia, 2009, Volume: 23, Issue:3

    Topics: Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Combined Modality Therapy; Cytarabine;

2009
Detection of submicroscopic disease in the bone marrow and unaffected testis of a child with T-cell acute lymphoblastic leukemia who experienced "isolated" testicular relapse.
    International journal of hematology, 2009, Volume: 90, Issue:3

    Topics: Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Bone Marrow; Child; Combined Modality

2009
Prognostic relevance of TLX3 (HOX11L2) expression in childhood T-cell acute lymphoblastic leukaemia treated with Berlin-Frankfurt-Münster (BFM) protocols containing early and late re-intensification elements.
    British journal of haematology, 2010, Volume: 148, Issue:2

    Topics: Adolescent; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Aus

2010
[Transient hyperlipidemia secondary to treatment with asparaginase and prednisone].
    Anales de pediatria (Barcelona, Spain : 2003), 2010, Volume: 72, Issue:1

    Topics: Antineoplastic Agents; Asparaginase; Child; Glucocorticoids; Humans; Hyperlipidemias; Male; Precurso

2010
Significance of myeloid antigen expression in precursor T lymphoblastic lymphoma.
    Chinese journal of cancer, 2010, Volume: 29, Issue:3

    Topics: Adolescent; Adult; Age Factors; Aged; Antigens, CD7; Antigens, Differentiation, Myelomonocytic; Anti

2010
Concurrent treatment of steroid-related mood and psychotic symptoms with risperidone.
    Pediatrics, 2010, Volume: 125, Issue:5

    Topics: Administration, Oral; Adolescent; Antineoplastic Agents, Hormonal; Antipsychotic Agents; Child; Dexa

2010
Biphenotypic hematologic malignancy: a case report of the 8p11 myeloproliferative syndrome in a child.
    Journal of pediatric hematology/oncology, 2010, Volume: 32, Issue:6

    Topics: Antineoplastic Combined Chemotherapy Protocols; Child; Chromosomes, Human, Pair 13; Chromosomes, Hum

2010
NOTCH1 and/or FBXW7 mutations predict for initial good prednisone response but not for improved outcome in pediatric T-cell acute lymphoblastic leukemia patients treated on DCOG or COALL protocols.
    Leukemia, 2010, Volume: 24, Issue:12

    Topics: Cell Cycle Proteins; Child; F-Box Proteins; F-Box-WD Repeat-Containing Protein 7; Female; Gene Rearr

2010
The favorable effect of activating NOTCH1 receptor mutations on long-term outcome in T-ALL patients treated on the ALL-BFM 2000 protocol can be separated from FBXW7 loss of function.
    Leukemia, 2010, Volume: 24, Issue:12

    Topics: Cell Cycle Proteins; Child; F-Box Proteins; F-Box-WD Repeat-Containing Protein 7; Humans; Mutation;

2010
Composite T lymphoblastic leukemia/lymphoma and diffuse large B-cell lymphoma: case report.
    Pathology international, 2011, Volume: 61, Issue:6

    Topics: Aged; Antibodies, Monoclonal, Murine-Derived; Antigens, CD; Antineoplastic Combined Chemotherapy Pro

2011
Clinical significance of early T-cell precursor acute lymphoblastic leukaemia: results of the Tokyo Children's Cancer Study Group Study L99-15.
    British journal of haematology, 2012, Volume: 156, Issue:3

    Topics: Adolescent; Antigens, CD; Antigens, Neoplasm; Antineoplastic Combined Chemotherapy Protocols; Child;

2012
A case of severe toxicity during coadministration of vincristine and piperacillin: are drug transporters involved in vincristine hypersensitivity and drug-drug interactions?
    Journal of pediatric hematology/oncology, 2012, Volume: 34, Issue:8

    Topics: Abdominal Pain; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; ATP Binding Cassette T

2012