prednisone has been researched along with Osteonecrosis in 102 studies
Prednisone: A synthetic anti-inflammatory glucocorticoid derived from CORTISONE. It is biologically inert and converted to PREDNISOLONE in the liver.
prednisone : A synthetic glucocorticoid drug that is particularly effective as an immunosuppressant, and affects virtually all of the immune system. Prednisone is a prodrug that is converted by the liver into prednisolone (a beta-hydroxy group instead of the oxo group at position 11), which is the active drug and also a steroid.
Osteonecrosis: Death of a bone or part of a bone, either atraumatic or posttraumatic.
| Excerpt | Relevance | Reference |
|---|---|---|
| " We report a rare case of bilateral steroid-induced osteonecrosis of the proximal femora and humeri nine months after a short course of intravenous methylprednisolone for treatment of multiple myeloma." | 3.83 | Bilateral Osteonecrosis of the Femoral and Humeral Heads after Short Term Corticosteroid Therapy. A Case Study. ( Ed AlTayeb Mussa, M; Eh Samir Ansara, S; El Gamal, TA; El-Bakoury, A; Er Ahmed Sweed, T; Hawkins, A, 2016) |
| "Maximal prednisone doses, changes in body habitus in response to corticosteroid therapy, IgG aCL levels, and clinical evidence of venous thrombosis and vasculitis were associated with osteonecrosis in patients with SLE." | 3.69 | Risk factors for osteonecrosis in systemic lupus erythematosus. ( Glueck, CJ; Hungerford, DS; Mont, MA; Pacheco, IH; Petri, M; Wang, P, 1997) |
| "We have described a 60-year-old woman with polymyalgia rheumatica treated initially with prednisone but ultimately with azathioprine and cyclophosphamide." | 3.67 | Trigeminal herpes zoster causing mandibular osteonecrosis and spontaneous tooth exfoliation. ( Canter, HG; Manz, HJ; Melton, J, 1986) |
| "We report a case of osteonecrosis in a 26-year-old woman treated with prednisone for immune thrombocytopenic purpura." | 3.67 | Osteonecrosis in a patient with immune thrombocytopenic purpura. ( Anderson, T; Chelmowski, MK; Smith, RE, 1987) |
| "Osteonecrosis of both lateral femoral condyles was observed in a 42-year-old black woman under treatment with oral prednisone." | 3.67 | Steroid-induced bilateral avascular necrosis of the lateral femoral condyles. A case report. ( Ebraheim, NA; Havel, PE; Jackson, WT, 1989) |
| "We investigated whether age, race, sex, acute lymphoblastic leukemia treatment arm, body mass, serum lipids, albumin and cortisol levels, dexamethasone pharmacokinetics, and genome-wide germline genetic polymorphisms were associated with symptomatic osteonecrosis." | 2.76 | Pharmacokinetic, pharmacodynamic, and pharmacogenetic determinants of osteonecrosis in children with acute lymphoblastic leukemia. ( Cai, X; Cheng, C; Evans, WE; Howard, SC; Kaste, SC; Kawedia, JD; Neale, G; Panetta, JC; Pei, D; Pui, CH; Relling, MV, 2011) |
| "Although our prednisone dosing data could not be used as an accurate predictor of onset or joint distribution, there was a tendency for correlation between the average daily dosing and the ARCO score." | 2.43 | Inflammatory bowel disease related osteonecrosis: report of a large series with a review of the literature. ( Klingenstein, G; Kornbluth, A; Levy, RN; Present, DH; Shah, AK, 2005) |
| "Two databases of men with testicular cancer were reviewed." | 2.41 | Nontraumatic osteonecrosis after chemotherapy for testicular cancer: a systematic review. ( Balogh, J; Bauman, GS; Winquist, EW, 2001) |
| "African American patients with systemic lupus erythematosus are at double the risk of experiencing ON compared to White patients." | 1.72 | Predictors of Osteonecrosis in Systemic Lupus Erythematosus: A Prospective Cohort Study. ( Kallas, R; Li, J; Petri, M, 2022) |
| " Five hundred and seventy-two patients were excluded due to insufficient documentation of oral corticosteroid dosage, no radiographic evidence supporting the diagnosis of AVN, insufficient data confirming the temporal relationship between oral corticosteroids and AVN, and/or a cumulative dosing of >10,000 mg prednisone." | 1.72 | Oral corticosteroid use and the risk of developing avascular necrosis: A large retrospective review. ( Campbell, DA; Grond, SE; Little, RE; Loehrl, TA; Poetker, DM, 2022) |
| "• Osteonecrosis is a possible complication of patients with Lymphoma treated by chemotherapy." | 1.46 | Osteonecrosis detected by whole body magnetic resonance in patients with Hodgkin Lymphoma treated by BEACOPP. ( Albano, D; Brancatelli, G; Galia, M; Grassedonio, E; La Grutta, L; Lagalla, R; Midiri, M; Mulè, A; Patti, C, 2017) |
| "Osteonecrosis was identified in 10 patients (41·7%, 95% confidence interval: 22·0-61·4%), with a total of 56 osteonecrotic sites." | 1.46 | Whole-body MRI reveals high incidence of osteonecrosis in children treated for Hodgkin lymphoma. ( Beishuizen, A; Bruin, MC; de Lange, C; Enríquez, G; Granata, C; Kwee, TC; Littooij, AS; Nievelstein, RA; Verbeke, JI; Zennaro, F, 2017) |
| "Prednisone doses were calculated at the end of the fourth year of follow-up (prednisone-4)." | 1.40 | Glucocorticoids and irreversible damage in patients with systemic lupus erythematosus. ( Cabezas-Rodriguez, I; Medina, JA; Moran, MA; Ruiz-Arruza, I; Ruiz-Irastorza, G; Ugarte, A, 2014) |
| "We document a high incidence of aseptic bone necrosis, possibly related to prednisolone." | 1.38 | Two escalated followed by six standard BEACOPP in advanced-stage high-risk classical Hodgkin lymphoma: high cure rates but increased risk of aseptic osteonecrosis. ( Aurlien, E; Blystad, AK; Fiskvik, IH; Fosså, A; Hole, KH; Holte, H; Ikonomou, IM; Kolstad, A; Lauritzsen, GF, 2012) |
| "The osteonecrosis was diagnosed an average of 38." | 1.35 | Symptomatic osteonecrosis of the hip and knee after cardiac transplantation. ( Dorey, FJ; Elsissy, P; Kobashigawa, JA; Lieberman, JR; Roth, KM, 2008) |
| "Ninety-seven consecutive patients with childhood ALL were studied prospectively by magnetic resonance imaging (MRI) of the lower extremities at the end of the treatment." | 1.34 | High body mass index increases the risk for osteonecrosis in children with acute lymphoblastic leukemia. ( Harila-Saari, AH; Jartti, AE; Lanning, M; Möttönen, MI; Niinimäki, RA; Pääkkö, EL; Riikonen, PV; Seuri, RM, 2007) |
| " She had received several bouts of steroids and had been in clinical remission for 12 weeks under a dosage of 40 mg/d prednisone." | 1.33 | [Recurrent aseptic osteonecrosis in Crohn's disease - extraintestinal manifestation or steroid related complication?]. ( Dienes, HP; Kruis, W; Lanyi, B, 2005) |
| " Although arthroplasty is safe in the general population, its safety in liver transplant recipients is unclear." | 1.32 | The safety and outcome of joint replacement surgery in liver transplant recipients. ( Cohen, SM; Levitsky, J; Te, HS, 2003) |
| "Prednisone was used as the corticosteroid during postremission therapy from 1987 to 1991, and dexamethasone was used from 1991 to 1995." | 1.31 | Bony morbidity in children treated for acute lymphoblastic leukemia. ( Dalton, VM; Gelber, RD; Sallan, SE; Silverman, LB; Strauss, AJ; Su, JT, 2001) |
| "A patient with sarcoidosis developed minimal change disease presenting as the nephrotic syndrome." | 1.30 | Sarcoid-associated minimal change disease: a case report. ( Cochrane, J; Healy, GF; North-Coombes, JD, 1998) |
| "Identifying patients with autoimmune premature ovarian failure presents the opportunity to restore ovarian function by treating these patients with the proper immune modulation therapy." | 1.30 | Treatment of autoimmune premature ovarian failure. ( Braddock, DT; Kalantaridou, SN; Nelson, LM; Patronas, NJ, 1999) |
| "In conclusion, avascular necrosis of bone is a frequent late complication of allogeneic bone marrow transplantation causing significant morbidity and requiring replacement surgery in one-third of affected patients." | 1.29 | Avascular necrosis of bone after allogeneic bone marrow transplantation: clinical findings, incidence and risk factors. ( Devergie, A; Esperou Bourdeau, H; Frija, J; Gluckman, E; Ribaud, P; Sedel, L; Sélimi, F; Socié, G, 1994) |
| "Thirteen patients with systemic lupus erythematosus (SLE) without avascular necrosis and with long-term corticosteroid treatment and 12 healthy subjects were evaluated." | 1.29 | Femoral head perfusion and composition: MR imaging and spectroscopic evaluation of patients with systemic lupus erythematosus and at risk for avascular necrosis. ( Bluemke, DA; Petri, M; Zerhouni, EA, 1995) |
| "Osteonecrosis is a common sequela of long-term steroid therapy." | 1.28 | Multifocal osteonecrosis after short-term high-dose corticosteroid therapy. A case report. ( Mack, GR; O'Brien, TJ, 1992) |
| " The latency period between the steroid therapy and the occurrence of AON ranged from 12 to 60 months; steroid therapy lasted for 12 to 16 days with a total dosage equivalent to 2370-7180 mg prednisolone." | 1.28 | [Craniocerebral trauma and aseptic osteonecrosis. Steroid-induced sequelae after therapy of brain edema]. ( Griss, P; Pfeiffer, M, 1992) |
| "Avascular necrosis of bone is a frequent late complication of bone marrow transplantation, causing significant morbidity and often requiring surgery; diagnosis using conventional imaging techniques may be difficult and treatment remains inadequate." | 1.28 | Avascular necrosis of bone: a common serious complication of allogeneic bone marrow transplantation. ( Enright, H; Haake, R; Weisdorf, D, 1990) |
| "Osteonecrosis is a serious complication of steroid therapy characterized by death of all the cellular elements of bone." | 1.28 | Steroid-related osteonecrosis in inflammatory bowel disease. ( Sparberg, M; Vakil, N, 1989) |
| "A 26-year-old white woman developed systemic lupus erythematosus (SLE) and extensive soft tissue calcification." | 1.27 | Systemic lupus erythematosus and diffuse soft tissue calcifications. ( Carette, S; Urowitz, MB, 1983) |
| " Careful tailoring of dosage is important to avoid adrenal atrophy and signs of adrenocortical hypofunction." | 1.27 | Corticosteroids for rheumatic disease. 1. Physiology, pharmacology, and therapeutic strategies. ( Jamieson, T, 1986) |
| "A patient with systemic lupus erythematosus who developed osteonecrosis in 13 sites is presented." | 1.27 | Multiple osteonecrotic lesions in systemic lupus erythematosus. ( Avrahami, E; Caspi, D; Eventov, I; Fishel, B; Yaron, M, 1987) |
| "Two cases of systemic lupus erythematosus (SLE) developing avascular bone necrosis are described." | 1.26 | Systemic lupus erythematosus and avascular bone necrosis. ( Nilsen, KH, 1977) |
| " Limited weight bearing and reduction in the dosage of prednisone failed to prevent the progressive destruction of five femoral heads in three patients." | 1.26 | Aseptic necrosis after renal transplantation in children. ( Ettenger, RB; Fine, RN; Isaacson, AS; Malekzadeh, MH; Pennisi, AJ; Stanley, P; Uittenbogaart, CH, 1978) |
| " The dosage of corticosteroids ingested during the initial period of therapy in patients with AN was tabulated and compared with that of 25 SLE control patients." | 1.26 | Aseptic necrosis of bone in systemic lupus erythematosus. Relationship to corticosteroid therapy. ( Abeles, M; Rothfield, NF; Urman, JD, 1978) |
| "Aseptic necrosis of the wrist in systemic lupus erythematosus (SLE) is not rare." | 1.26 | Aseptic necrosis presenting as wrist pain in SLE. ( Abeles, M; Houghton, AN; Rothfield, NF; Urman, JD, 1977) |
| "A patient with idiopathic thrombocytopenia purpura who was treated with high dosage corticosteroids for ten years, developed 18 separate lesions of avascular necrosis in 12 different bones." | 1.26 | Steroid induced avascular necrosis of bones in eighteen sites: a case report. ( Milgram, JW; Riley, LH, 1976) |
| "A patient with pemphigus vulgaris, treated with long term corticosteroids, developed avascular necrosis of the head of the femur and humerus, bilaterally." | 1.24 | Avascular bone necrosis. A complication of long-term corticosteroid therapy. ( Epstein, JH; Epstein, NN; Tuffanelli, DL, 1965) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 47 (46.08) | 18.7374 |
| 1990's | 20 (19.61) | 18.2507 |
| 2000's | 17 (16.67) | 29.6817 |
| 2010's | 13 (12.75) | 24.3611 |
| 2020's | 5 (4.90) | 2.80 |
| Authors | Studies |
|---|---|
| Moriya, K | 1 |
| Imamura, T | 1 |
| Katayama, S | 1 |
| Kaino, A | 1 |
| Okamoto, K | 1 |
| Yokoyama, N | 1 |
| Uemura, S | 1 |
| Kitazawa, H | 1 |
| Sekimizu, M | 1 |
| Hiramatsu, H | 1 |
| Usami, I | 1 |
| Ishida, H | 1 |
| Hasegawa, D | 1 |
| Hama, A | 1 |
| Moriya-Saito, A | 1 |
| Sato, A | 1 |
| Sasahara, Y | 1 |
| Suenobu, S | 1 |
| Horibe, K | 1 |
| Hara, J | 1 |
| Grond, SE | 1 |
| Little, RE | 1 |
| Campbell, DA | 1 |
| Loehrl, TA | 1 |
| Poetker, DM | 1 |
| Sugiyama, M | 1 |
| Terashita, Y | 1 |
| Cho, Y | 1 |
| Iguchi, A | 1 |
| Arai, R | 1 |
| Takakuwa, E | 1 |
| Honda, S | 1 |
| Manabe, A | 1 |
| Ruiz-Irastorza, G | 2 |
| Ugarte, A | 2 |
| Ruiz-Arruza, I | 2 |
| Khamashta, M | 1 |
| Kallas, R | 1 |
| Li, J | 1 |
| Petri, M | 3 |
| Basic-Kinda, S | 1 |
| Karlak, I | 1 |
| Durakovic, N | 1 |
| Lubina, ZI | 1 |
| Livaja Radman, I | 1 |
| Dotlic, S | 1 |
| Peric, Z | 1 |
| Hude, I | 1 |
| Aurer, I | 1 |
| Albano, D | 2 |
| Patti, C | 2 |
| Midiri, M | 2 |
| Galia, M | 2 |
| Salem, KH | 1 |
| Brockert, AK | 1 |
| Mertens, R | 1 |
| Drescher, W | 1 |
| Cabezas-Rodriguez, I | 1 |
| Medina, JA | 1 |
| Moran, MA | 1 |
| Toft, N | 1 |
| Birgens, H | 1 |
| Abrahamsson, J | 1 |
| Griškevičius, L | 1 |
| Hallböök, H | 1 |
| Heyman, M | 1 |
| Klausen, TW | 1 |
| Jónsson, ÓG | 1 |
| Palk, K | 1 |
| Pruunsild, K | 1 |
| Quist-Paulsen, P | 1 |
| Vaitkeviciene, G | 1 |
| Vettenranta, K | 1 |
| Asberg, A | 1 |
| Helt, LR | 1 |
| Frandsen, T | 1 |
| Schmiegelow, K | 1 |
| La Grutta, L | 1 |
| Grassedonio, E | 1 |
| Mulè, A | 1 |
| Brancatelli, G | 1 |
| Lagalla, R | 1 |
| Tsang-A-Sjoe, MW | 1 |
| Bultink, IE | 1 |
| Heslinga, M | 1 |
| Voskuyl, AE | 1 |
| Littooij, AS | 1 |
| Kwee, TC | 1 |
| Enríquez, G | 1 |
| Verbeke, JI | 1 |
| Granata, C | 1 |
| Beishuizen, A | 1 |
| de Lange, C | 1 |
| Zennaro, F | 1 |
| Bruin, MC | 1 |
| Nievelstein, RA | 1 |
| El Gamal, TA | 1 |
| El-Bakoury, A | 1 |
| Hawkins, A | 1 |
| Ed AlTayeb Mussa, M | 1 |
| Er Ahmed Sweed, T | 1 |
| Eh Samir Ansara, S | 1 |
| Yildiz, N | 1 |
| Ardic, F | 1 |
| Deniz, S | 1 |
| McAvoy, S | 1 |
| Baker, KS | 1 |
| Mulrooney, D | 1 |
| Blaes, A | 1 |
| Arora, M | 1 |
| Burns, LJ | 1 |
| Majhail, NS | 1 |
| Kawedia, JD | 1 |
| Kaste, SC | 2 |
| Pei, D | 1 |
| Panetta, JC | 1 |
| Cai, X | 1 |
| Cheng, C | 1 |
| Neale, G | 1 |
| Howard, SC | 1 |
| Evans, WE | 1 |
| Pui, CH | 2 |
| Relling, MV | 2 |
| Fosså, A | 1 |
| Fiskvik, IH | 1 |
| Kolstad, A | 1 |
| Lauritzsen, GF | 1 |
| Aurlien, E | 1 |
| Blystad, AK | 1 |
| Hole, KH | 1 |
| Ikonomou, IM | 1 |
| Holte, H | 1 |
| Mattano, LA | 2 |
| Devidas, M | 1 |
| Nachman, JB | 2 |
| Sather, HN | 2 |
| Hunger, SP | 1 |
| Steinherz, PG | 1 |
| Gaynon, PS | 1 |
| Seibel, NL | 1 |
| Levitsky, J | 1 |
| Te, HS | 1 |
| Cohen, SM | 1 |
| Aricò, M | 1 |
| Boccalatte, MF | 1 |
| Silvestri, D | 1 |
| Barisone, E | 1 |
| Messina, C | 1 |
| Chiesa, R | 1 |
| Santoro, N | 1 |
| Tamaro, P | 1 |
| Lippi, A | 1 |
| Gallisai, D | 1 |
| Basso, G | 1 |
| De Rossi, G | 1 |
| RAVAULT, PP | 1 |
| LEJEUNE, E | 1 |
| COLOMB, D | 1 |
| FRIES, D | 1 |
| MADELL, SH | 1 |
| FREEMAN, LM | 1 |
| EPSTEIN, NN | 2 |
| TUFFANELLI, DL | 2 |
| EPSTEIN, JH | 2 |
| UEHLINGER, E | 1 |
| Bürger, B | 1 |
| Beier, R | 1 |
| Zimmermann, M | 1 |
| Beck, JD | 1 |
| Reiter, A | 1 |
| Schrappe, M | 1 |
| Klingenstein, G | 1 |
| Levy, RN | 1 |
| Kornbluth, A | 1 |
| Shah, AK | 1 |
| Present, DH | 1 |
| Lanyi, B | 1 |
| Dienes, HP | 1 |
| Kruis, W | 1 |
| Hodek-Wuerz, R | 1 |
| Steinke, K | 1 |
| Tasic, V | 1 |
| Trajkovski, Z | 1 |
| Zafirovski, G | 1 |
| Gucev, Z | 1 |
| Trompeter, RS | 1 |
| Sawicka-Zukowska, M | 1 |
| Kajdas, L | 1 |
| Muszynska-Roslan, K | 1 |
| Krawczuk-Rybak, M | 1 |
| Sonta-Jakimczyk, D | 1 |
| Szczepanski, T | 1 |
| Niinimäki, RA | 1 |
| Harila-Saari, AH | 1 |
| Jartti, AE | 1 |
| Seuri, RM | 1 |
| Riikonen, PV | 1 |
| Pääkkö, EL | 1 |
| Möttönen, MI | 1 |
| Lanning, M | 1 |
| Richards, RN | 1 |
| Lieberman, JR | 1 |
| Roth, KM | 1 |
| Elsissy, P | 1 |
| Dorey, FJ | 1 |
| Kobashigawa, JA | 1 |
| Conklin, JJ | 1 |
| Alderson, PO | 1 |
| Zizic, TM | 4 |
| Hungerford, DS | 4 |
| Densereaux, JY | 1 |
| Gober, A | 1 |
| Wagner, HN | 1 |
| Feletti, C | 1 |
| Di Felice, A | 1 |
| Scolari, MP | 1 |
| Bonomini, V | 1 |
| Halpin, TC | 1 |
| Dahms, BB | 1 |
| Carette, S | 1 |
| Urowitz, MB | 1 |
| Kawai, H | 1 |
| Tsuyuguchi, Y | 1 |
| Yonenobu, K | 1 |
| Inoue, A | 1 |
| Tada, K | 1 |
| Hérics, I | 1 |
| Szántó, I | 1 |
| Liszka, G | 1 |
| Webb, DR | 1 |
| Prindull, G | 1 |
| Weigel, W | 1 |
| Jentsch, E | 1 |
| Enderle, A | 1 |
| Willert, HG | 1 |
| Sok, M | 1 |
| Muhvić, R | 1 |
| Pozar, B | 1 |
| Belin, J | 1 |
| Linck-Dubost, M | 1 |
| Michel, JL | 1 |
| Merle, P | 1 |
| Viallet, JF | 1 |
| Belin, B | 1 |
| Prosnitz, LR | 1 |
| Lawson, JP | 1 |
| Friedlaender, GE | 1 |
| Farber, LR | 1 |
| Pezzimenti, JF | 1 |
| Gregg, PJ | 1 |
| Barsoum, MK | 1 |
| Soppitt, D | 1 |
| Jackson, RH | 1 |
| Bluemke, DA | 1 |
| Zerhouni, EA | 1 |
| Clarke, AE | 1 |
| Bloch, DA | 1 |
| Medsger, TA | 1 |
| Oddis, CV | 1 |
| Cowan, J | 1 |
| Moenning, JE | 1 |
| Bussard, DA | 1 |
| Knight, A | 1 |
| Socié, G | 1 |
| Sélimi, F | 1 |
| Sedel, L | 1 |
| Frija, J | 1 |
| Devergie, A | 1 |
| Esperou Bourdeau, H | 1 |
| Ribaud, P | 1 |
| Gluckman, E | 1 |
| Fryer, JP | 1 |
| Granger, DK | 1 |
| Leventhal, JR | 1 |
| Gillingham, K | 1 |
| Najarian, JS | 1 |
| Matas, AJ | 1 |
| Beyer, CA | 1 |
| Beckenbaugh, RD | 1 |
| Mont, MA | 1 |
| Glueck, CJ | 1 |
| Pacheco, IH | 1 |
| Wang, P | 1 |
| Felchle, LM | 1 |
| McPhee, LA | 1 |
| Kerr, ME | 1 |
| Houston, DM | 1 |
| Krishnamurthy, AB | 1 |
| Finn, HA | 1 |
| North-Coombes, JD | 1 |
| Healy, GF | 1 |
| Cochrane, J | 1 |
| Elstein, D | 1 |
| Abrahamov, A | 1 |
| Itzchaki, M | 1 |
| Zimran, A | 1 |
| Kalantaridou, SN | 1 |
| Braddock, DT | 1 |
| Patronas, NJ | 1 |
| Nelson, LM | 1 |
| Trigg, ME | 1 |
| Weinstein, RS | 1 |
| Manolagas, SC | 1 |
| Strauss, AJ | 1 |
| Su, JT | 1 |
| Dalton, VM | 1 |
| Gelber, RD | 1 |
| Sallan, SE | 1 |
| Silverman, LB | 1 |
| Ribeiro, RC | 1 |
| Fletcher, BD | 1 |
| Kennedy, W | 1 |
| Harrison, PL | 1 |
| Neel, MD | 1 |
| Sandlund, JT | 1 |
| Rubnitz, JE | 1 |
| Razzouk, BI | 1 |
| Winquist, EW | 1 |
| Bauman, GS | 1 |
| Balogh, J | 1 |
| O'Regan, S | 1 |
| Chesney, RW | 1 |
| Hamstra, A | 1 |
| Eisman, JA | 1 |
| O'Gorman, AM | 1 |
| Deluca, HF | 1 |
| Nilsen, KH | 1 |
| Grub, R | 1 |
| Heni, N | 1 |
| Baumeister, L | 1 |
| Heerfordt, J | 1 |
| Olgaard, K | 1 |
| Madsen, S | 1 |
| Vistisen, L | 1 |
| Jensen, H | 1 |
| Løokkegaard, H | 1 |
| Brix, E | 1 |
| Uittenbogaart, CH | 1 |
| Isaacson, AS | 1 |
| Stanley, P | 1 |
| Pennisi, AJ | 1 |
| Malekzadeh, MH | 1 |
| Ettenger, RB | 1 |
| Fine, RN | 1 |
| Potter, DE | 1 |
| Genant, HK | 1 |
| Salvatierra, O | 1 |
| Ruderman, RJ | 1 |
| Poehling, GG | 1 |
| Gray, R | 1 |
| Nardone, M | 1 |
| Goodman, W | 1 |
| Seigler, HF | 1 |
| Abeles, M | 2 |
| Urman, JD | 2 |
| Rothfield, NF | 2 |
| Houghton, AN | 1 |
| Hummer, CD | 1 |
| Milgram, JW | 1 |
| Riley, LH | 1 |
| Smith, FE | 1 |
| Sweet, DE | 1 |
| Brunner, CM | 1 |
| Davis, JS | 1 |
| Buskila, D | 1 |
| Thomson, GT | 1 |
| Klein, M | 1 |
| Keystone, EC | 1 |
| Virgolini, L | 1 |
| De Maglio, A | 1 |
| O'Brien, TJ | 1 |
| Mack, GR | 1 |
| Chancelier, MD | 1 |
| Hélénon, O | 1 |
| Page, B | 1 |
| Rousselin, B | 1 |
| Legendre, C | 1 |
| Moreau, JF | 1 |
| Pfeiffer, M | 1 |
| Griss, P | 1 |
| Enright, H | 1 |
| Haake, R | 1 |
| Weisdorf, D | 1 |
| Murphy, RG | 1 |
| Greenberg, ML | 1 |
| Gold, DA | 1 |
| Abdelwahab, IF | 1 |
| Hermann, G | 2 |
| Bömelburg, T | 1 |
| von Lengerke, HJ | 1 |
| Ritter, J | 1 |
| Havel, PE | 1 |
| Ebraheim, NA | 1 |
| Jackson, WT | 1 |
| van Leeuwen, HJ | 1 |
| Witkamp, D | 1 |
| Verdonck, LF | 1 |
| Huber-Bruning, O | 1 |
| van der Veen, MJ | 1 |
| Bijlsma, JW | 1 |
| Hayes, JM | 1 |
| Vakil, N | 1 |
| Sparberg, M | 1 |
| Yamaguchi, H | 1 |
| Masuda, T | 2 |
| Sasaki, T | 2 |
| Nojima, T | 1 |
| Jamieson, T | 1 |
| Fishel, B | 1 |
| Caspi, D | 1 |
| Eventov, I | 1 |
| Avrahami, E | 1 |
| Yaron, M | 1 |
| Smith, RE | 1 |
| Chelmowski, MK | 1 |
| Anderson, T | 1 |
| Freishtat, HW | 1 |
| Yagi, T | 1 |
| Monji, J | 1 |
| Yasuda, K | 1 |
| Fukazawa, M | 1 |
| Konno, H | 1 |
| Manz, HJ | 1 |
| Canter, HG | 1 |
| Melton, J | 1 |
| Blijham, GH | 1 |
| Vermeulen, A | 1 |
| Mendes de Leon, DE | 1 |
| Shpall, EJ | 1 |
| Efremidis, AP | 1 |
| Kasambalides, E | 1 |
| Sedlin, E | 1 |
| Marcoux, C | 1 |
| Dansereau, JV | 1 |
| Stevens, MB | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Total XV - Total Therapy Study XV for Newly Diagnosed Patients With Acute Lymphoblastic Leukemia[NCT00137111] | Phase 3 | 501 participants (Actual) | Interventional | 2000-07-08 | Completed | ||
| Treatment of Patients With Acute Lymphoblastic Leukemia With Unfavorable Features: A Phase III Group-wide Study[NCT00002812] | Phase 3 | 2,078 participants (Actual) | Interventional | 1996-09-30 | Completed | ||
| [NCT00005436] | 0 participants | Observational | 1991-09-30 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
"White blood cell (leukocytes) counts in peripheral blood by Complete Blood Count~Measurement: Percentage change of leukemia cells from baseline" (NCT00137111)
Timeframe: Immediately before the methotrexate infusion and three days after subsequent infusion
| Intervention | Percent change (Mean) |
|---|---|
| 4 hr | -44 |
| 24 hr | -50 |
CCR was measured from end of week 56 therapy to the date of first treatment failure of any kind (relapse, death, lineage switch, or second malignancy) or to the last date of follow-up. Measurement was determined by Kaplan-Meyer estimate. (NCT00137111)
Timeframe: Median follow up time (range) 4.5 (1 to 7.8) years
| Intervention | Percentage of participants (Number) |
|---|---|
| Patients With High Risk of CNS Relapse | 92.2 |
Children were randomly assigned to receive initial single-agent treatment with HDMTX (1g/m^2) as either a 24-hour infusion or a 4-hour infusion and the outcome measure was the accumulation of MTXPG in leukemia cells. (NCT00137111)
Timeframe: 42 hours after start of high dose methotrexate infusion (HDMTX)
| Intervention | pmol/1,000,000,000 cells (Mean) |
|---|---|
| 4 hr | 1688 |
| 24 hr | 2521 |
EFS was measured from the start of on-study to the date of first treatment failure of any kind (relapse, death, lineage switch, or second malignancy) or to the last date of follow-up. Failure to enter remission was considered an event at time zero. Measurement was determined by Kaplan-Meyer estimate. (NCT00137111)
Timeframe: Median follow-up time (range) 5.6 (1.3 to 8.9) years
| Intervention | Percentage of Participants (Number) |
|---|---|
| Total Therapy | 87.3 |
Prednisolone sensitivity was measured in primary leukemia cells from bone marrow collected at diagnosis. Expression of CASP1 was determined by HG-U133A microarray. Values given are gene expression values, and the unit is arbitrary units (AU) defined as scaled fluorescence measured on microarray. (NCT00137111)
Timeframe: Pre-treatment
| Intervention | arbitrary units (Median) | |
|---|---|---|
| Prednisolone-sensitive cells | Prednisolone-resistant cells | |
| Total Therapy | 341.3 | 447.9 |
Prednisolone sensitivity was measured in primary leukemia cells from bone marrow collected at diagnosis. Expression of NLRP3 was determined by HG-U133A microarray. Values given are gene expression values, and the unit is arbitrary units (AU) defined as scaled fluorescence measured on microarray. (NCT00137111)
Timeframe: Pre-treatment
| Intervention | arbitrary units (Median) | |
|---|---|---|
| Prednisolone-sensitive cells | Prednisolone-resistant cells | |
| Total Therapy | 41.2 | 110.7 |
Detection of MRD at end of induction where positive MRD was defined as one or more leukemic cell per 10,000 mononuclear bone-marrow cells (>=0.01%). (NCT00137111)
Timeframe: End of Induction (Day 46 MRD measurement)
| Intervention | participants (Number) | |
|---|---|---|
| Negative <0.01% | Positive >= 0.01% | |
| Total Therapy | 390 | 102 |
7 reviews available for prednisone and Osteonecrosis
| Article | Year |
|---|---|
Seventy years after Hench's Nobel prize: revisiting the use of glucocorticoids in systemic lupus erythematosus.
Topics: Administration, Oral; Disease Progression; Dose-Response Relationship, Drug; Drug Tapering; Female; | 2020 |
Inflammatory bowel disease related osteonecrosis: report of a large series with a review of the literature.
Topics: Adult; Cohort Studies; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Gluco | 2005 |
Short-term corticosteroids and avascular necrosis: medical and legal realities.
Topics: Drug Administration Schedule; Glucocorticoids; Humans; Malpractice; Osteonecrosis; Prednisone | 2007 |
Systemic lupus erythematosus X: corticosteroid therapy and its complications.
Topics: Anemia, Hemolytic; Central Nervous System Diseases; Cushing Syndrome; Humans; Kidney Diseases; Lupus | 1984 |
Steroids in allergic disease.
Topics: Administration, Intranasal; Adrenal Cortex Hormones; Asthma; Beclomethasone; Cataract; Cushing Syndr | 1981 |
Apoptosis and osteoporosis.
Topics: Adrenal Cortex Hormones; Animals; Anti-Inflammatory Agents; Apoptosis; Bone Regeneration; Bone Remod | 2000 |
Nontraumatic osteonecrosis after chemotherapy for testicular cancer: a systematic review.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Femur Head Necrosis; Glucocorticoids; Humans; | 2001 |
4 trials available for prednisone and Osteonecrosis
| Article | Year |
|---|---|
Pharmacokinetic, pharmacodynamic, and pharmacogenetic determinants of osteonecrosis in children with acute lymphoblastic leukemia.
Topics: Antineoplastic Agents, Hormonal; Child; Dexamethasone; Genome-Wide Association Study; Humans; Magnet | 2011 |
Effect of alternate-week versus continuous dexamethasone scheduling on the risk of osteonecrosis in paediatric patients with acute lymphoblastic leukaemia: results from the CCG-1961 randomised cohort trial.
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Child; Child, Preschool; C | 2012 |
Osteonecrosis: An emerging complication of intensive chemotherapy for childhood acute lymphoblastic leukemia.
Topics: Adolescent; Antineoplastic Agents, Hormonal; Child; Dexamethasone; Drug Therapy, Combination; Female | 2003 |
Osteonecrosis as a complication of treating acute lymphoblastic leukemia in children: a report from the Children's Cancer Group.
Topics: Adolescent; Adult; Age Factors; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Presch | 2000 |
91 other studies available for prednisone and Osteonecrosis
| Article | Year |
|---|---|
The incidence of symptomatic osteonecrosis is similar between Japanese children and children in Western countries with acute lymphoblastic leukaemia treated with a Berlin-Frankfurt-Münster (BFM)95-based protocol.
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Child; Child, Preschool; C | 2022 |
Oral corticosteroid use and the risk of developing avascular necrosis: A large retrospective review.
Topics: Adrenal Cortex Hormones; Adult; Humans; Osteonecrosis; Prednisone; Retrospective Studies; Risk Facto | 2022 |
Successful treatment of dumbbell-shaped Hodgkin lymphoma with massive sacral bone destruction.
Topics: Antineoplastic Combined Chemotherapy Protocols; Child; Cyclophosphamide; Female; Hodgkin Disease; Hu | 2020 |
Predictors of Osteonecrosis in Systemic Lupus Erythematosus: A Prospective Cohort Study.
Topics: Cohort Studies; Female; Humans; Lupus Erythematosus, Systemic; Male; Osteonecrosis; Prednisone; Pros | 2022 |
High incidence of aseptic hip necrosis in Hodgkin lymphoma patients treated with escalated BEACOPP receiving methylprednisolone.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cross-Sectional Studies; Cyclophos | 2018 |
Osteonecrosis in Hodgkin lymphoma treated by BEACOPP.
Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cyclophosphamide; Doxorubicin; Etoposide; | 2018 |
Avascular necrosis after chemotherapy for haematological malignancy in childhood.
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Arthroplasty, Replacement, Hip; Child; C | 2013 |
Glucocorticoids and irreversible damage in patients with systemic lupus erythematosus.
Topics: Adult; Cataract; Cohort Studies; Diabetes Mellitus; Female; Glucocorticoids; Humans; Lupus Erythemat | 2014 |
Toxicity profile and treatment delays in NOPHO ALL2008-comparing adults and children with Philadelphia chromosome-negative acute lymphoblastic leukemia.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Female; | 2016 |
Osteonecrosis detected by whole body magnetic resonance in patients with Hodgkin Lymphoma treated by BEACOPP.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cyclophosphamide; Dose | 2017 |
Both prolonged remission and Lupus Low Disease Activity State are associated with reduced damage accrual in systemic lupus erythematosus.
Topics: Adult; Arthritis; Cataract; Cohort Studies; Diabetes Mellitus; Disease Progression; Female; Glucocor | 2017 |
Whole-body MRI reveals high incidence of osteonecrosis in children treated for Hodgkin lymphoma.
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Child; Doxorubicin; Epiphyses; Etoposide | 2017 |
Bilateral Osteonecrosis of the Femoral and Humeral Heads after Short Term Corticosteroid Therapy. A Case Study.
Topics: Femur Head Necrosis; Humans; Humerus; Magnetic Resonance Imaging; Male; Methylprednisolone; Middle A | 2016 |
Very early onset steroid-induced avascular necrosis of the hip and knee in a patient with idiopathic thrombocytopenic purpura.
Topics: Female; Hip Joint; Humans; Knee Joint; Middle Aged; Osteonecrosis; Prednisone; Purpura, Thrombocytop | 2008 |
Corticosteroid dose as a risk factor for avascular necrosis of the bone after hematopoietic cell transplantation.
Topics: Adolescent; Adult; Case-Control Studies; Child; Child, Preschool; Dose-Response Relationship, Drug; | 2010 |
Two escalated followed by six standard BEACOPP in advanced-stage high-risk classical Hodgkin lymphoma: high cure rates but increased risk of aseptic osteonecrosis.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Chemotherapy, Adjuvant | 2012 |
The safety and outcome of joint replacement surgery in liver transplant recipients.
Topics: Adrenal Cortex Hormones; Aged; Arthritis; Arthroplasty, Replacement; Drug Administration Schedule; F | 2003 |
[Osteonecrosis of the femur head associated with corticotherapy].
Topics: Femur Head; Humans; Necrosis; Osteochondritis; Osteonecrosis; Prednisone | 1962 |
AVASCULAR NECROSIS OF BONE IN CUSHING'S SYNDROME.
Topics: Adrenal Gland Neoplasms; Adrenalectomy; Adrenocorticotropic Hormone; Cushing Syndrome; Hip Joint; Hu | 1964 |
AVASCULAR BONE NECROSIS, A COMPLICATION OF LONG-TERM CORTICOSTEROID THERAPY.
Topics: Adrenal Cortex Hormones; Bone Diseases; Drug Therapy; Femur Head; Humans; Humerus; Joint Diseases; N | 1965 |
[ASEPTIC BONE NECROSIS (INFARCT) AFTER PREDNISONE THERAPY].
Topics: Bone Diseases; Necrosis; Osteonecrosis; Prednisone; Toxicology | 1964 |
Osteonecrosis: a treatment related toxicity in childhood acute lymphoblastic leukemia (ALL)--experiences from trial ALL-BFM 95.
Topics: Adolescent; Child; Child, Preschool; Dexamethasone; Female; Glucocorticoids; Hip Joint; Humans; Infa | 2005 |
[Recurrent aseptic osteonecrosis in Crohn's disease - extraintestinal manifestation or steroid related complication?].
Topics: Anti-Inflammatory Agents; Arthroplasty, Replacement, Hip; Biopsy; Bone and Bones; Bone Density; Croh | 2005 |
[Secondary osteonecrosis: steroid therapy and its possible sequelae].
Topics: Anti-Inflammatory Agents; Diagnosis, Differential; Follow-Up Studies; Granulomatosis with Polyangiit | 2005 |
Aseptic necrosis of both tali in a child with steroid-dependent nephrotic syndrome.
Topics: Adrenal Cortex Hormones; Child, Preschool; Cyclosporine; Female; Humans; Nephrotic Syndrome; Osteone | 2006 |
Avascular necrosis--an antineoplastic-treatment-related toxicity: the experiences of two institutions.
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Cyclophosphamide; Cytarabi | 2006 |
High body mass index increases the risk for osteonecrosis in children with acute lymphoblastic leukemia.
Topics: Adolescent; Adrenal Cortex Hormones; Age Distribution; Analysis of Variance; Body Mass Index; Causal | 2007 |
Symptomatic osteonecrosis of the hip and knee after cardiac transplantation.
Topics: Adolescent; Adult; Aged; Female; Femur Head Necrosis; Glucocorticoids; Heart Transplantation; Humans | 2008 |
Comparison of bone scan and radiograph sensitivity in the detection of steroid-induced ischemic necrosis of bone.
Topics: Adolescent; Adult; Aged; Arthrography; Diphosphonates; Female; Femur Head Necrosis; Humans; Joints; | 1983 |
Glucocorticoids and avascular bone necrosis in renal transplantation.
Topics: Adult; Drug Therapy, Combination; Female; Femur Head Necrosis; Glucocorticoids; Graft Rejection; Hum | 1984 |
Complications associated with intravenous lipids in infants & children.
Topics: Adolescent; Chemical and Drug Induced Liver Injury; Child, Preschool; Crohn Disease; Drug Interactio | 1983 |
Systemic lupus erythematosus and diffuse soft tissue calcifications.
Topics: Adult; Calcinosis; Female; Humans; Lupus Erythematosus, Systemic; Osteonecrosis; Prednisone; Skin; T | 1983 |
Avascular necrosis of the carpal scaphoid associated with progressive systemic sclerosis.
Topics: Adult; Carpal Bones; Female; Humans; Osteonecrosis; Prednisone; Scleroderma, Systemic | 1983 |
[Steroid-induced aseptic necrosis in patients with malignant lymphoma].
Topics: Adult; Female; Humans; Lymphoma; Male; Middle Aged; Osteonecrosis; Prednisone | 1984 |
Aseptic osteonecrosis in children treated for acute lymphoblastic leukemia and aplastic anemia.
Topics: Adolescent; Anemia, Aplastic; Child; Dexamethasone; Female; Femur; Femur Head Necrosis; Humans; Hume | 1982 |
[Osteonecrosis of the humeral head in a patient with bronchial asthma].
Topics: Adult; Asthma; Humans; Humerus; Male; Osteonecrosis; Prednisone | 1982 |
[Vertebral void caused by postcorticoid osteonecrosis].
Topics: Aged; Female; Humans; Osteonecrosis; Prednisone; Radiography; Spinal Diseases; Thoracic Vertebrae | 1982 |
Avascular necrosis of bone in Hodgkin's disease patients treated with combined modality therapy.
Topics: Adult; Antineoplastic Agents; Drug Therapy, Combination; Female; Femur Head Necrosis; Hodgkin Diseas | 1981 |
II. The treatment of ischemic necrosis of bone in systemic lupus erythematosus.
Topics: Adult; Anti-Inflammatory Agents; Female; Femur Head; Femur Head Necrosis; Hip Prosthesis; Humans; Lu | 1980 |
Avascular necrosis of bone in children receiving high-dose steroid treatment.
Topics: Adolescent; Adult; Child; Child, Preschool; Drug Administration Schedule; Humans; Infant; Kidney Dis | 1980 |
Femoral head perfusion and composition: MR imaging and spectroscopic evaluation of patients with systemic lupus erythematosus and at risk for avascular necrosis.
Topics: Adipose Tissue; Adolescent; Adult; Bone Marrow; Case-Control Studies; Contrast Media; Drug Combinati | 1995 |
A longitudinal study of functional disability in a national cohort of patients with polymyositis/dermatomyositis.
Topics: Adult; Aged; Cohort Studies; Dermatomyositis; Disability Evaluation; Disabled Persons; Disease Progr | 1995 |
Glucocorticoid therapy for myasthenia gravis resulting in resorption of the mandibular condyles.
Topics: Adult; Bone Resorption; Female; Humans; Mandibular Condyle; Mandibular Diseases; Myasthenia Gravis; | 1995 |
Images in clinical medicine: corticosteroid osteonecrosis.
Topics: Humans; Osteonecrosis; Prednisone | 1995 |
Avascular necrosis of bone after allogeneic bone marrow transplantation: clinical findings, incidence and risk factors.
Topics: Acute Disease; Adolescent; Adult; Age Factors; Anemia, Aplastic; Bone Marrow Transplantation; Child; | 1994 |
Steroid-related complications in the cyclosporine era.
Topics: Adult; Age Factors; Bacterial Infections; Bone Diseases; Cataract; Cyclosporine; Diabetes Mellitus; | 1994 |
Bilateral capitellar steroid-induced avascular necrosis.
Topics: Adult; Arthroplasty; Female; Humans; Humerus; Osteonecrosis; Prednisone; Radiography | 1993 |
Risk factors for osteonecrosis in systemic lupus erythematosus.
Topics: Adolescent; Adult; Aged; Anti-Inflammatory Agents; Antibodies, Anticardiolipin; Biomarkers; Female; | 1997 |
Systemic lupus erythematosus and bone marrow necrosis in a dog.
Topics: Animals; Anti-Inflammatory Agents; Antibodies, Antinuclear; Antirheumatic Agents; Arthritis; Azathio | 1996 |
Osteonecrosis of the proximal tibia.
Topics: Adult; Female; Glucocorticoids; Humans; Kidney Transplantation; Osteonecrosis; Prednisone; Radiograp | 1998 |
Sarcoid-associated minimal change disease: a case report.
Topics: Adult; Anti-Inflammatory Agents; Female; Glucocorticoids; Humans; Lung Diseases; Nephrosis, Lipoid; | 1998 |
Commentary: low-dose high-frequency enzyme replacement therapy prevents fractures without complete suppression of painful bone crises in patients with severe juvenile onset type I Gaucher disease.
Topics: Adolescent; Adult; Age Factors; Animals; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Ste | 1998 |
Treatment of autoimmune premature ovarian failure.
Topics: Adult; Autoimmune Diseases; Cushing Syndrome; Dexamethasone; Female; Glucocorticoids; Humans; Iatrog | 1999 |
Bony morbidity in children treated for acute lymphoblastic leukemia.
Topics: Adolescent; Analysis of Variance; Antineoplastic Agents, Hormonal; Boston; Child; Child, Preschool; | 2001 |
Magnetic resonance imaging detection of avascular necrosis of the bone in children receiving intensive prednisone therapy for acute lymphoblastic leukemia or non-Hodgkin lymphoma.
Topics: Adolescent; Age Factors; Antineoplastic Combined Chemotherapy Protocols; Arthralgia; Arthroplasty, R | 2001 |
Avascular bone necrosis. A complication of long-term corticosteroid therapy.
Topics: Adrenocorticotropic Hormone; Female; Femur Head Necrosis; Glucocorticoids; Humans; Humerus; Middle A | 1965 |
Reduced serum 1,25-(OH)2 vitamin D3 levels in prednisone-treated adolescents with systemic lupus erythematosus.
Topics: Adolescent; Adult; Child; Cholecalciferol; Humans; Hydroxycholecalciferols; Lupus Erythematosus, Sys | 1979 |
Systemic lupus erythematosus and avascular bone necrosis.
Topics: Adult; Betamethasone; Female; Humans; Lupus Erythematosus, Systemic; Male; Osteonecrosis; Prednisone | 1977 |
[Aseptic necrosis of the femoral head in lymphogranulomatosis and chronic myeloic leukemia treated intermittently with cytostatic agents and steroids (author's transl)].
Topics: Adult; Antineoplastic Agents; Femur Head Necrosis; Hodgkin Disease; Humans; Humerus; Leukemia, Myelo | 1978 |
Osteoscintigraphic changes in kidney-transplanted patients.
Topics: Adult; Bone and Bones; Bone Diseases; Female; Humans; Kidney Failure, Chronic; Kidney Transplantatio | 1978 |
Aseptic necrosis after renal transplantation in children.
Topics: Adolescent; Bone Diseases; Child; Female; Femur Head Necrosis; Humans; Kidney Transplantation; Male; | 1978 |
Avascular necrosis of bone after renal transplantation.
Topics: Adolescent; Child; Child, Preschool; Female; Femur Head Necrosis; Humans; Hyperparathyroidism, Secon | 1978 |
Orthopedic complications of renal transplantation in children.
Topics: Adolescent; Age Factors; Child; Dose-Response Relationship, Drug; Female; Humans; Immunosuppression | 1979 |
Aseptic necrosis of bone in systemic lupus erythematosus. Relationship to corticosteroid therapy.
Topics: Adult; Child; Cortisone; Dose-Response Relationship, Drug; Female; Humans; Lupus Erythematosus, Syst | 1978 |
Aseptic necrosis presenting as wrist pain in SLE.
Topics: Adolescent; Adult; Carpal Bones; Child; Diagnosis, Differential; Diagnostic Errors; Humans; Lupus Er | 1977 |
Avascular necrosis of the capital femoral epiphysis in a child receiving corticosteroids: a case report.
Topics: Braces; Child; Epiphyses; Female; Femur Head; Humans; Osteonecrosis; Prednisone; Radiography; Tracti | 1977 |
Steroid induced avascular necrosis of bones in eighteen sites: a case report.
Topics: Adult; Female; Humans; Osteonecrosis; Prednisone; Radiography; Thrombocytopenia | 1976 |
Avascular necrosis in SLE. An apparent predilection for young patients.
Topics: Adolescent; Adult; Age Factors; Aged; Child; Femur Head; Femur Head Necrosis; Humans; Lupus Erythema | 1976 |
Avascular necrosis of bone mimicking symmetric polyarthritis in a patient with malignant lymphoma treated with high-dose steroids.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Arthritis, Rheumatoid; Bleomycin; Cyclophosph | 1992 |
Bilateral aseptic necrosis of the humeral head following combined therapy for Hodgkin's lymphoma.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Female; Hodgkin Di | 1992 |
Multifocal osteonecrosis after short-term high-dose corticosteroid therapy. A case report.
Topics: Adult; Femur Head Necrosis; Humans; Humerus; Magnetic Resonance Imaging; Male; Methylprednisolone; O | 1992 |
[Aseptic osteonecrosis of the knee induced by corticoids. MRI aspects].
Topics: Adult; Female; Follow-Up Studies; Humans; Kidney Transplantation; Knee; Lupus Erythematosus, Systemi | 1992 |
[Craniocerebral trauma and aseptic osteonecrosis. Steroid-induced sequelae after therapy of brain edema].
Topics: Adolescent; Adult; Brain Edema; Brain Injuries; Cortisone; Female; Femur Head Necrosis; Humans; Male | 1992 |
Avascular necrosis of bone: a common serious complication of allogeneic bone marrow transplantation.
Topics: Adolescent; Adult; Age Factors; Bone Marrow Transplantation; Child; Child, Preschool; Confidence Int | 1990 |
Osteonecrosis in pediatric patients with acute lymphoblastic leukemia.
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Child; Dexamethasone; Female; Femur; Fem | 1990 |
Osteonecrosis of both medial tibial condyles following short-term steroid therapy. A case report.
Topics: Adult; Humans; Male; Osteonecrosis; Prednisone; Radiography; Tibia | 1989 |
Aseptic osteonecroses in the treatment of childhood acute leukaemias.
Topics: Adolescent; Child; Child, Preschool; Femur Head Necrosis; Humans; Immobilization; Infant; Leukemia, | 1989 |
Steroid-induced bilateral avascular necrosis of the lateral femoral condyles. A case report.
Topics: Adult; Female; Femur; Humans; Knee Joint; Osteonecrosis; Prednisone; Radiography; Radionuclide Imagi | 1989 |
Multiple sites of ischemic necrosis of bone following long term corticosteroid treatment in a patient with auto-immune granulocytopenia.
Topics: Adult; Agranulocytosis; Autoimmune Diseases; Humans; Magnetic Resonance Imaging; Male; Osteonecrosis | 1989 |
Arthroscopic treatment of steroid-induced osteonecrosis of the humeral head.
Topics: Crohn Disease; Humans; Humerus; Joint Loose Bodies; Male; Middle Aged; Osteonecrosis; Prednisone; Sh | 1989 |
Steroid-related osteonecrosis in inflammatory bowel disease.
Topics: Adult; Female; Humans; Inflammatory Bowel Diseases; Male; Osteonecrosis; Prednisone; Retrospective S | 1989 |
Steroid-induced osteonecrosis of the patella.
Topics: Adrenal Cortex Hormones; Adult; Asthma; Biopsy; Female; Humans; Lupus Erythematosus, Systemic; Male; | 1988 |
Corticosteroids for rheumatic disease. 1. Physiology, pharmacology, and therapeutic strategies.
Topics: Adrenal Cortex; Adrenal Cortex Hormones; Drug Administration Schedule; Humans; Hypothalamo-Hypophyse | 1986 |
Multiple osteonecrotic lesions in systemic lupus erythematosus.
Topics: Adult; Diagnosis, Differential; Female; Humans; Lupus Erythematosus, Systemic; Osteonecrosis; Predni | 1987 |
Osteonecrosis in a patient with immune thrombocytopenic purpura.
Topics: Adult; Female; Humans; Osteonecrosis; Prednisone; Purpura, Thrombocytopenic | 1987 |
View from the Nation's Courts. Informed consent: how little is too little?
Topics: Humans; Informed Consent; Jurisprudence; Osteonecrosis; Prednisone; Risk; United States | 1986 |
Steroid-induced osteonecrosis of the femoral condyle--a clinical study of eighteen knees in ten patients.
Topics: Adult; Female; Femur; Humans; Knee; Male; Osteonecrosis; Prednisone; Radiography | 1986 |
Trigeminal herpes zoster causing mandibular osteonecrosis and spontaneous tooth exfoliation.
Topics: Azathioprine; Cranial Nerve Diseases; Cyclophosphamide; Drug Therapy, Combination; Female; Herpes Zo | 1986 |
Osteonecrosis of sternum and rib in a patient treated for Hodgkin's disease.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Hodgkin Disease; H | 1985 |
Case report 352: Osteonecrosis of the femoral shaft (probably steroid-induced).
Topics: Adult; Diagnosis, Differential; Female; Femur; Humans; Osteonecrosis; Prednisone | 1986 |
Corticosteroid therapy associated with ischemic necrosis of bone in systemic lupus erythematosus.
Topics: Adolescent; Adult; Aged; Bone and Bones; Drug Administration Schedule; Female; Follow-Up Studies; Hu | 1985 |