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prednisone and Obesity

prednisone has been researched along with Obesity in 99 studies

Prednisone: A synthetic anti-inflammatory glucocorticoid derived from CORTISONE. It is biologically inert and converted to PREDNISOLONE in the liver.
prednisone : A synthetic glucocorticoid drug that is particularly effective as an immunosuppressant, and affects virtually all of the immune system. Prednisone is a prodrug that is converted by the liver into prednisolone (a beta-hydroxy group instead of the oxo group at position 11), which is the active drug and also a steroid.

Obesity: A status with BODY WEIGHT that is grossly above the recommended standards, usually due to accumulation of excess FATS in the body. The standards may vary with age, sex, genetic or cultural background. In the BODY MASS INDEX, a BMI greater than 30.0 kg/m2 is considered obese, and a BMI greater than 40.0 kg/m2 is considered morbidly obese (MORBID OBESITY).

Research Excerpts

ExcerptRelevanceReference
"After mastectomy, 265 postmenopausal patients with node-positive breast cancer were stratified according to pathologic nodal status and estrogen-receptor (ER) status and randomized to receive either 12 cycles of cyclophosphamide, methotrexate, 5-fluorouracil, and prednisone (CMFP), or CMFP plus tamoxifen (CMFPT), or observation alone."9.05Adjuvant CMFP versus CMFP plus tamoxifen versus observation alone in postmenopausal, node-positive breast cancer patients: three-year results of an Eastern Cooperative Oncology Group study. ( Bennett, JM; Carbone, PP; Cummings, F; Falkson, G; Kalish, LA; Olson, JE; Taylor, SG; Tormey, DC, 1985)
"A prospective study was performed to evaluate the effect of long-term small-dose prednisone therapy in frequently relapsing nephrotic syndrome (NS); 37 patients were included, with a relapse rate 4."7.67Long-term, small dose prednisone therapy in frequently relapsing nephrotic syndrome of childhood. Effect on remission, statural growth, obesity, and infection rate. ( Elzouki, AY; Jaiswal, OP, 1988)
"We determined retrospectively the frequency and risk of hyperglycemia in 421 children with leukemia who had received L-asparaginase and prednisone as part of their remission induction therapy."7.66Risk factors for hyperglycemia in children with leukemia receiving L-asparaginase and prednisone. ( Aur, RJ; Bowman, WP; Burghen, GA; Pui, CH, 1981)
"After mastectomy, 265 postmenopausal patients with node-positive breast cancer were stratified according to pathologic nodal status and estrogen-receptor (ER) status and randomized to receive either 12 cycles of cyclophosphamide, methotrexate, 5-fluorouracil, and prednisone (CMFP), or CMFP plus tamoxifen (CMFPT), or observation alone."5.05Adjuvant CMFP versus CMFP plus tamoxifen versus observation alone in postmenopausal, node-positive breast cancer patients: three-year results of an Eastern Cooperative Oncology Group study. ( Bennett, JM; Carbone, PP; Cummings, F; Falkson, G; Kalish, LA; Olson, JE; Taylor, SG; Tormey, DC, 1985)
" The ability of emodin to inhibit prednisone- or dexamethasone-induced insulin resistance was investigated in C57BL/6J mice and its effect on metabolic abnormalities was observed in DIO mice."3.76Emodin, a natural product, selectively inhibits 11beta-hydroxysteroid dehydrogenase type 1 and ameliorates metabolic disorder in diet-induced obese mice. ( Chen, JH; Dou, W; Feng, Y; Huang, SL; Leng, Y; Shen, JH; Shen, Y; Zhang, S, 2010)
" Patients treated with a combination of prednisone and dexamethasone had as a late effect the highest prevalence of obesity (44%)."3.69Obesity after successful treatment of acute lymphoblastic leukemia in childhood. ( De Groot, A; Egeler, RM; Hählen, K; Hokken-Koelega, AC; Tromp, CG; Van Dongen-Melman, JE, 1995)
" Cyclosporine A plus steroid-based immuno-suppression regimens in these patients are associated with the development of hypertension, hyperlipidemia, obesity, and diabetes mellitus."3.69Evolution of cardiovascular risk after liver transplantation: a comparison of cyclosporine A and tacrolimus (FK506). ( Canzanello, VJ; Krom, RA; Porayko, MK; Schwartz, L; Taler, SJ; Textor, SC; Wiesner, RH, 1997)
"A prospective study was performed to evaluate the effect of long-term small-dose prednisone therapy in frequently relapsing nephrotic syndrome (NS); 37 patients were included, with a relapse rate 4."3.67Long-term, small dose prednisone therapy in frequently relapsing nephrotic syndrome of childhood. Effect on remission, statural growth, obesity, and infection rate. ( Elzouki, AY; Jaiswal, OP, 1988)
"The severity and persistence of corticosteroid-induced obesity were evaluated retrospectively in 23 children aged 1-14 yrs requiring more than 60 days of therapy with prednisone for idiopathic nephrotic syndrome."3.67Corticosteroid therapy-induced obesity in children. ( Hack, SL; Kalsch, M; Merritt, RJ; Olson, D, 1986)
"We determined retrospectively the frequency and risk of hyperglycemia in 421 children with leukemia who had received L-asparaginase and prednisone as part of their remission induction therapy."3.66Risk factors for hyperglycemia in children with leukemia receiving L-asparaginase and prednisone. ( Aur, RJ; Bowman, WP; Burghen, GA; Pui, CH, 1981)
" Then the medication was changed to that two days' dosage orally take once a day with the daily dose reduced by 5."2.71[Clinical study on intervention of liuwei dihuang pill on hormonotherapy in treating nephrotic syndrome]. ( Cao, EZ; Fang, Q; Hu, SJ; Liu, JS; Zhang, L, 2005)
" We used a different dosing regimen of prednisone to determine if benefit to boys with Duchenne muscular dystrophy might be maintained with fewer side effects."2.70High dose weekly oral prednisone improves strength in boys with Duchenne muscular dystrophy. ( Connolly, AM; Florence, J; Renna, R; Schierbecker, J, 2002)
"Both prednisone treatment and targeting Pebp1 pathway are promising strategies to alleviate inflammation and necroptosis that occurred in AAV gene therapy or related diseases."1.91AAV induces hepatic necroptosis and carcinoma in diabetic and obese mice dependent on Pebp1 pathway. ( Cheng, Y; Dong, J; Feng, N; Gao, P; Han, Y; He, Z; Huang, R; Lai, H; Yang, Y; Yu, H; Zhai, Q; Zhang, Y; Zhang, Z; Zhong, W, 2023)
"A girl aged 14 years was admitted with stridor."1.62Stridor Due to Cranial Nerve X Palsy Progressing to Polyneuropathy in a Teenager With COVID-19. ( Chelius, D; Dean, A; Marri, K; Said, A, 2021)
"Idiopathic intracranial hypertension is a diagnosis of exclusion and imaging studies should always be performed to rule out other structural and obstructive lesions."1.51Idiopathic intracranial hypertension presenting with isolated unilateral facial nerve palsy: a case report. ( Berry, B; Ghannam, M; Ghazaleh, D; Samara, A, 2019)
"To study if obesity is a risk factor in elderly patients (>60 years) with aggressive B-cell lymphoma, the outcomes of 576 elderly patients treated with rituximab in the RICOVER-60 trial were analysed in a retrospective study with regard to body mass index (BMI) and gender."1.48Obesity negatively impacts outcome in elderly female patients with aggressive B-cell lymphomas treated with R-CHOP: results from prospective trials of the German high grade non-Hodgkin's lymphoma trial group. ( Altmann, B; Hohloch, K; Loeffler, M; Pfreundschuh, M; Schmitz, N; Trümper, L; Zettl, F; Ziepert, M, 2018)
"Being obese or underweight at diagnosis and for ≥ 50% of the time between end of induction and start of maintenance therapy resulted in inferior EFS (hazard ratios, 1."1.40Impact on survival and toxicity by duration of weight extremes during treatment for pediatric acute lymphoblastic leukemia: A report from the Children's Oncology Group. ( Freyer, DR; Gaynon, PS; Ladas, E; Malvar, J; Orgel, E; Seibel, NL; Sposto, R, 2014)
"Obesity was associated with younger age, lower PSA and alkaline phosphatase levels, and higher performance status, primary Gleason sum, testosterone and hemoglobin compared to absence of obesity."1.35The relationship of body mass index and serum testosterone with disease outcomes in men with castration-resistant metastatic prostate cancer. ( Armstrong, AJ; de Wit, R; Eisenberger, M; Halabi, S; Tannock, IF, 2009)
"Prednisone was started during the ambulant phase at age 3."1.35Prednisone 10 days on/10 days off in patients with Duchenne muscular dystrophy. ( de Groot, IJ; Overweg-Plandsoen, WC; Straathof, CS; van den Burg, GJ; van der Kooi, AJ; Verschuuren, JJ, 2009)
"Successful treatment of higher risk childhood ALL was associated with obesity, independent of cranial irradiation."1.35Weight patterns in children with higher risk ALL: A report from the Children's Oncology Group (COG) for CCG 1961. ( Hawks, RG; Meza, JL; Post-White, JE; Sacks, N; Seibel, NL; Smith, LM; Withycombe, JS, 2009)
"Troglitazone (TGZ) treatment, beginning at 6 weeks of age, prevented the hyperglycemia, the hyperlipidemia, and the increase in 11beta-HSD-1."1.32Increased expression and activity of 11beta-HSD-1 in diabetic islets and prevention with troglitazone. ( Agarwal, AK; Duplomb, L; Lee, Y; Park, BH; Takaishi, K; Unger, RH; Wang, MY, 2004)
"Obesity is a concern in the long-term management of patients following liver transplantation, yet the risk of obesity and the factors that influence its development have not been well defined."1.30Weight change and obesity after liver transplantation: incidence and risk factors. ( Everhart, JE; Hoofnagle, JH; Lake, JR; Lombardero, M; Wiesner, RH; Zetterman, RK, 1998)
"Severe obesity is a greater risk factor for incisional hernia and hernia recurrence than chronic steroid use in nonobese colitis patients."1.29Greater risk of incisional hernia with morbidly obese than steroid-dependent patients and low recurrence with prefascial polypropylene mesh. ( DeMaria, EJ; Kellum, JM; Lowry, JW; Newsome, HH; Reines, HD; Sugerman, HJ, 1996)
"Hyperlipidemia and hypertension, two major risk factors for accelerated atherosclerosis, undoubtedly contribute to the excessive cardiovascular morbidity and mortality experienced by renal transplant recipients."1.28Lipid abnormalities in cyclosporine-prednisone-treated renal transplant recipients. ( Goldstein, RA; Grevel, J; Kahan, BD; Lewis, RM; Schoenberg, L; Van Buren, CT; Vathsala, A; Weinberg, RB, 1989)
"Three patients with liver cirrhosis showed severe myelosuppression and fever."1.28[Feasibility of CHOP chemotherapy--with special reference to age, diabetes mellitus, liver cirrhosis and obesity]. ( Fujii, H; Hashimoto, S; Hiramatsu, H; Kondo, M; Kuribayashi, T; Yorozu, A, 1989)
"Obesity is accompanied by altered secretion and disposition of sex and glucocorticoid hormones, including cortisol, and also confounds parameter normalization and drug dosage selection relative to body weight."1.27Prednisolone disposition in obese men. ( Jusko, WJ; Milsap, RL; Plaisance, KI, 1984)
"Complications of BIH include recurrence of the syndrome, visual impairment and development of the empty sells syndrome."1.25Benign intracranial hypertension. ( Weisberg, LA, 1975)
"Obesity was associated with abnormally raised blood pyruvate levels in response to a glucose tolerance test in all groups."1.25Effects of obesity, glucocorticoid, and oral contraceptive therapy on plasma glucose and blood pyruvate levels. ( Doar, JW; Wynn, V, 1970)

Research

Studies (99)

TimeframeStudies, this research(%)All Research%
pre-199056 (56.57)18.7374
1990's12 (12.12)18.2507
2000's10 (10.10)29.6817
2010's14 (14.14)24.3611
2020's7 (7.07)2.80

Authors

AuthorsStudies
Kaviani, A1
Khansari Nejad, N1
Akour, A1
AlMuhaissen, SA1
Nusair, MB1
Al-Tammemi, AB1
Mahmoud, NN1
Jalouqa, S1
Alrawashdeh, MN1
Shanahan, JP1
Moore, CM1
Kampf, JW1
Szymczak, NK1
Guo, J1
Wang, H1
Luo, Y1
An, H1
Zhang, Z3
Liu, G1
Li, J2
Metcalfe, GD1
Smith, TW1
Hippler, M1
Ayala Izurieta, JE1
Márquez, CO1
García, VJ1
Jara Santillán, CA1
Sisti, JM1
Pasqualotto, N1
Van Wittenberghe, S1
Delegido, J1
Kubo, Y1
Kitagawa, Y1
Miyazaki, T1
Sohda, M1
Yamaji, T1
Sakai, M1
Saeki, H1
Nemoto, K1
Oyama, T2
Muto, M1
Takeuchi, H1
Toh, Y1
Matsubara, H1
Mano, M1
Kono, K1
Kato, K1
Yoshida, M1
Kawakubo, H1
Booka, E1
Yamatsuji, T1
Kato, H1
Ito, Y1
Ishikawa, H1
Ishihara, R1
Tsushima, T1
Kawachi, H1
Kojima, T1
Kuribayashi, S1
Makino, T1
Matsuda, S1
Doki, Y1
Ma, P1
Tang, X1
Zhang, L3
Wang, X2
Wang, W1
Zhang, X2
Wang, S3
Zhou, N1
Dodd, J1
Jordan, R1
Makhlina, M1
Pesco Koplowitz, L1
Koplowitz, B1
Barnett, K1
Yang, WH1
Spana, C1
Buchanan, SW1
Mafa-Attoye, T1
Dunfield, K1
Thevathasan, NV1
Isaac, ME1
Wu, X3
Huang, JW1
Su, BK1
Yuan, L1
Zheng, WQ1
Zhang, H3
Zheng, YX1
Zhu, W1
Chou, PT1
Manso, AP1
De Morais, DC1
Yamamoto, K1
Owen, G1
de Carvalho, RM1
Palma-Dibb, RG1
Brown, JC1
Yang, S1
Mire, EF1
Miele, L1
Ochoa, A1
Zabaleta, J1
Katzmarzyk, PT1
Moi, CT1
Bhowmick, S1
Qureshi, M1
Wang, K1
Feng, B1
Yang, Y3
Chen, Y1
Wang, Y2
Yang, L1
Jiang, K1
James, TD1
Chaturvedi, V1
Postiglione, WM1
Chakraborty, RD1
Yu, B1
Tabiś, W1
Hameed, S1
Biniskos, N1
Jacobson, A1
Zhou, H1
Greven, M1
Ferry, VE1
Leighton, C1
Wu, F1
Lei, H1
Chen, G1
Chen, C1
Song, Y1
Cao, Z1
Zhang, C2
Zhou, J1
Lu, Y1
Pappone, C1
Santinelli, V1
Mecarocci, V1
Tondi, L1
Ciconte, G1
Manguso, F1
Sturla, F1
Vicedomini, G1
Micaglio, E1
Anastasia, L1
Pica, S1
Camporeale, A1
Lombardi, M1
Shieh, PB1
Elfring, G1
Trifillis, P1
Santos, C1
Peltz, SW1
Parsons, JA1
Apkon, S1
Darras, BT1
Campbell, C1
McDonald, CM1
Galaviz, KI1
Shah, NS1
Gutierrez, M1
Collins, LF1
Lahiri, CD1
Moran, CA1
Szabo, B1
Sumitani, J1
Rhodes, J1
Marconi, VC1
Nguyen, ML1
Cantos, VD1
Armstrong, WS1
Colasanti, JA1
Dean, A1
Said, A1
Marri, K1
Chelius, D1
Quattrocelli, M1
Wintzinger, M1
Miz, K1
Panta, M1
Prabakaran, AD1
Barish, GD1
Chandel, NS1
McNally, EM1
Soliman, AT1
Hamed, N1
De Sanctis, V1
Elbaba, M1
Alyafei, F1
Alaaraj, N1
Ahmad, S1
Itani, M1
Al-Naimi, F1
Khater, D1
Benarous, X1
Brocheton, C1
Bonnay, C1
Boissel, L1
Crovetto, C1
Lahaye, H1
Guilé, JM1
Theret, P1
Gondry, J1
Foulon, A1
Kim, E1
Yoo, SH1
Chen, Z1
Sousa, JA1
Batista, E1
Demeyer, S1
Fischer, N1
Pellegrino, O1
Ribeiro, AS1
Martins, LL1
Worthy, FR1
Goldberg, SD1
Ranjitkar, S1
Xu, JC1
Asmara, AAGY1
Karna, MB1
Meregawa, PF1
Deslivia, MF1
Carula, BC1
Giostri, GS1
Bebber, F1
Batista, MFDS1
Silva, FBD1
Novak, EM1
Vilela, JCS1
Franco, N1
Campos, G1
Deligne, LM1
Machado, TLA1
Degasperi, FA1
Scatigna, BF1
Falótico, GG1
Romero, V1
Basile, R1
Takata, ET1
Kaleka, CC1
Debieux, P1
Antonioli, E1
Zucconi, E1
Cohen, M1
Ferretti, M1
Bampidis, V2
Azimonti, G2
Bastos, ML2
Christensen, H2
Fašmon Durjava, M2
Kouba, M2
López-Alonso, M2
López Puente, S2
Marcon, F2
Mayo, B2
Pechová, A2
Petkova, M2
Ramos, F2
Sanz, Y2
Villa, RE2
Woutersen, R2
Brantom, P2
Chesson, A2
Westendorf, J2
Manini, P2
Pizzo, F2
Dusemund, B2
Aron, J1
Albert, PS1
Gribble, MO1
Samankul, A1
Senawong, G1
Swatsitang, P1
Sripa, B1
Phaosiri, C1
Kanokmedhakul, S1
Senawong, T1
Sirajudeen, MS1
Alzhrani, M1
Alanazi, A1
Alqahtani, M1
Waly, M1
Unnikrishnan, R1
Muthusamy, H1
Alrubaia, W1
Alanazi, N1
Seyam, MK1
Kashoo, F1
Miraj, M1
Channmgere Govindappa, S1
Alghamdi, KA1
Al-Hussinan, NM1
Wang, Z2
Qu, T1
Qi, H1
Zhao, S1
Shi, H2
Bai, W1
Yu, Y1
Zhao, P1
Yakubov, S1
Stockerl, WJ1
Tian, X1
Shahin, A1
Mandigma, MJP1
Gschwind, RM1
Barham, JP1
Li, R1
Jiang, D1
Du, P1
Yuan, C1
Cui, X1
Tang, Q1
Zheng, J1
Li, Y1
Lu, K1
Ren, X1
Gao, S1
Zhan, X1
Ramgoolam, KH1
Dolphin, AC1
Shi, Q1
Zhou, YJ1
Fang, JG1
Zhong, X1
Chen, LZ1
Hou, HZ1
Ma, L1
Feng, SZ1
He, JW1
Huang, R2
Wang, YF1
Guo, FL1
Li, LJ2
Ruan, XH2
Fu, GM1
Zhao, JZ2
Hou, XK1
Gao, M2
Zheng, XQ2
Zeng, Y1
Huang, DM1
Zhang, JM1
Kang, M1
Zhu, J1
Xu, YJ1
Li, SN1
Lai, JM1
Liu, JJ1
Wen, S1
Yan, HH1
Cheng, R1
Zhu, F1
Gao, PF1
Zou, HY1
Huang, CZ1
Wang, J1
AbdElgawad, H1
Zinta, G1
Hornbacher, J1
Papenbrock, J1
Markakis, MN1
Asard, H1
Beemster, GTS1
Fukushi, Y1
Akamine, Y1
Abumiya, M1
Tozawa, N1
Yamashita, T1
Nara, M1
Kameoka, Y1
Takahashi, N1
Miura, M1
Qi, G1
Yu, T1
Guo, Z1
Ma, K1
Jin, Y1
Lucon-Xiccato, T1
Montalbano, G1
Gatto, E1
Frigato, E1
D'Aniello, S1
Bertolucci, C1
Shi, W1
Ge, N1
Yu, S1
Wu, J1
Hu, T1
Wei, J1
Yan, X1
Lin, K1
Deng, T1
Qu, H1
Ou, H1
Huang, Q1
Gao, B1
Li, X1
Wei, N1
von Haeften, K1
Laarmann, T1
Wabnitz, H1
Möller, T1
Gries, KJ1
Hart, CR1
Kunz, HE1
Ryan, Z1
Parvizi, M1
Liu, Y1
Dasari, S1
Lanza, IR1
Perez, HL1
Andonian, C1
Wan, KX1
Potts, D1
Gonzalez, P1
Smith, I1
Kavetska, O1
Cheng, Y1
Gao, P1
Lai, H1
Zhong, W1
Feng, N1
Yu, H1
Zhang, Y1
Han, Y1
Dong, J1
He, Z1
Zhai, Q1
Karpouzas, GA1
Rezaeian, P1
Ormseth, SR1
Hollan, I1
Budoff, MJ1
Roberts, WC1
Won, VS1
Vasudevan, A1
Guileyardo, JM1
Yamamoto, M1
Hori, T1
Igarashi, K1
Iesato, K1
Saito, M1
Miyanishi, K1
Kikuchi, N1
Fujita, H1
Tsutsumi, H1
Hohloch, K1
Altmann, B1
Pfreundschuh, M1
Loeffler, M1
Schmitz, N1
Zettl, F1
Ziepert, M1
Trümper, L1
Samara, A1
Ghazaleh, D1
Berry, B1
Ghannam, M1
Hong, F1
Habermann, TM1
Gordon, LI1
Hochster, H1
Gascoyne, RD1
Morrison, VA1
Fisher, RI1
Bartlett, NL1
Stiff, PJ1
Cheson, BD1
Crump, M1
Horning, SJ1
Kahl, BS1
Orgel, E1
Sposto, R1
Malvar, J1
Seibel, NL2
Ladas, E1
Gaynon, PS1
Freyer, DR1
Courtney, MJ1
Chattopadhyay, D1
Rao, M1
Light, D1
Gopinath, B1
Chan, H1
Jackson, S1
McLay, J1
Knox, A1
Lee, J1
Issa, S1
Salt, E1
Wiggins, AT1
Rayens, MK1
Morris, BJ1
Mannino, D1
Hoellein, A1
Donegan, RP1
Crofford, LJ1
Armstrong, AJ1
Halabi, S1
de Wit, R1
Tannock, IF1
Eisenberger, M1
Straathof, CS1
Overweg-Plandsoen, WC1
van den Burg, GJ1
van der Kooi, AJ1
Verschuuren, JJ1
de Groot, IJ1
Withycombe, JS1
Post-White, JE1
Meza, JL1
Hawks, RG1
Smith, LM1
Sacks, N1
Sargis, RM1
Johnson, DN1
Choudhury, RA1
Brady, MJ1
Sánchez, C1
López-Jurado, M1
Aranda, P1
Llopis, J1
Feng, Y1
Huang, SL1
Dou, W1
Zhang, S1
Chen, JH1
Shen, Y1
Shen, JH1
Leng, Y1
Szymon, S1
Bik-Multanowski, M1
Balwierz, W1
Pietrzyk, JJ1
Surmiak, M1
Strojny, W1
Galicka-Latala, D1
Gozdzik, J1
Rosario, M1
Song, SX1
McCullough, LD1
Connolly, AM1
Schierbecker, J1
Renna, R1
Florence, J1
RIPA, R1
REINHARD, RE1
POLOSA, P1
MOTTA, L1
TURRISI, E1
KAEDING, A2
MACLEOD, SC1
MORSE, WI1
HIRSCH, S1
TOMPKINS, MG1
JACEY, G1
HENNING, L1
ENGLHARDT, A1
JAHNKE, K1
Duplomb, L1
Lee, Y1
Wang, MY1
Park, BH1
Takaishi, K1
Agarwal, AK1
Unger, RH1
Hu, SJ1
Fang, Q1
Liu, JS1
Cao, EZ1
Vester, U1
Schaefer, A1
Kranz, B1
Wingen, AM1
Nadalin, S1
Paul, A1
Malagò, M1
Broelsch, CE1
Hoyer, PF1
Foster, BJ1
Shults, J1
Zemel, BS1
Leonard, MB1
Blaim, A3
Leśkiewicz, W3
Golczyk-Wojnar, A2
Růzica, M1
Kataoka, S1
Kusunoki, T1
Wajchenberg, BL1
Prestes Cesar, F1
Okada, H1
Torres de Toledo e Souza, I1
Lerário, AC1
Borghi, VC1
Malerbi, DA1
Giurna Filho, A1
Liberman, B1
Gianella, D1
Pui, CH1
Burghen, GA1
Bowman, WP1
Aur, RJ1
Milsap, RL1
Plaisance, KI1
Jusko, WJ1
Persellin, ST1
Griffing, WL1
Michet, CJ1
Schroeder, KW1
Luthra, HS1
Broyer, M1
Tete, MJ1
Laudat, MH1
Goldstein, S1
Davisson, NA1
Westervelt, FB1
Bolton, WK1
Witt, ME1
Ginsberg-Fellner, F1
Van Dongen-Melman, JE1
Hokken-Koelega, AC1
Hählen, K1
De Groot, A1
Tromp, CG1
Egeler, RM1
Hilbrands, LB1
Demacker, PN1
Hoitsma, AJ1
Stalenhoef, AF1
Koene, RA1
Sugerman, HJ1
Kellum, JM1
Reines, HD1
DeMaria, EJ1
Newsome, HH1
Lowry, JW1
Mejía-Arangure, JM1
Fajardo-Gutíerrez, A1
Bernáldez-Ríos, R1
Rodríguez-Zepeda, MC1
Espinoza-Hernández, L1
Martínez-García, MC1
Drafts, HH1
Anjum, MR1
Wynn, JJ1
Mulloy, LL1
Bowley, JN1
Humphries, AL1
Canzanello, VJ1
Schwartz, L1
Taler, SJ1
Textor, SC1
Wiesner, RH2
Porayko, MK1
Krom, RA1
Everhart, JE1
Lombardero, M1
Lake, JR1
Zetterman, RK1
Hoofnagle, JH1
Markowitz, GS1
Tartini, A1
D'Agati, VD1
Sklar, CA1
Mertens, AC1
Walter, A1
Mitchell, D1
Nesbit, ME1
O'Leary, M1
Hutchinson, R1
Meadows, AT1
Robison, LL1
Wälchli, B1
Benini, A1
Rose, E1
Espinoza, LR1
Osterland, CK1
Zurbrügg, RP1
Ibels, LS1
Alfrey, AC1
Weil, R1
Diethelm, AG1
Sterling, WA1
Hartley, MW1
Morgan, JM1
Paulsen, EP1
Koury, M1
Weisberg, LA1
Mathieu, H1
Seff, DJ1
Pradignac, A1
Offner, C1
Friess, P1
Veillon, F1
Grunenberger, F1
Schlienger, JL1
Imler, M1
Petri, M2
Perez-Gutthann, S1
Spence, D2
Hochberg, MC2
Bone, LR1
McDiarmid, SV1
Gornbein, JA1
Fortunat, M1
Saikali, D1
Vargas, JH1
Busuttil, RW1
Ament, ME1
Vathsala, A1
Weinberg, RB1
Schoenberg, L1
Grevel, J1
Goldstein, RA1
Van Buren, CT1
Lewis, RM1
Kahan, BD1
Kuribayashi, T1
Kondo, M1
Yorozu, A1
Hiramatsu, H1
Fujii, H1
Hashimoto, S1
Elzouki, AY1
Jaiswal, OP1
Powis, G1
Reece, P1
Ahmann, DL1
Ingle, JN1
Taylor, SG1
Kalish, LA1
Olson, JE1
Cummings, F1
Bennett, JM1
Falkson, G1
Tormey, DC1
Carbone, PP1
Merritt, RJ1
Hack, SL1
Kalsch, M1
Olson, D1
Miller, RH1
Chen, JJ1
Ney, RL1
Tumulty, P1
Wieland, RG1
Zorn, EM1
Hallberg, MC1
Di Paola, G1
Puchulu, F1
Robin, M1
Nicholson, R1
Marti, M1
Tolentino, P1
Scriba, PC1
Strohmeyer, G1
Spuck, W1
Martini, GA1
el-Shaboury, AH1
Hayes, TM1
Cuatrecasas, P1
Bartsocas, CS1
Pantelakis, SN1
Sheagren, JN1
Simon, HB1
Rich, RR1
Cacciari, E1
Tassoni, P1
Dallera, L1
Miano, A1
Cicognani, A1
Spahn, U2
Voss, E1
Holtorff, J1
Haller, H1
Strauzenberg, E1
Haim, S1
Benderly, A1
Shafrir, A1
Levy, J1
Tabb, WC1
Guerrant, JL1
Doar, JW1
Wynn, V1
Teates, CD1
Fischer, P1
Nostitz, HJ1
Shagrin, JW1
Frame, B1
Duncan, H1
Jakobson, T1
Kahanpää, A1
Nikkilä, EA1
Smith, KD1
Steinberger, E1
Perloff, WH1
De Caro, LG1
Fattorini, A1
Gorini, M1
Becker, A1
Plenert, W1

Clinical Trials (8)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Treatment of Patients With Acute Lymphoblastic Leukemia With Unfavorable Features: A Phase III Group-wide Study[NCT00002812]Phase 32,078 participants (Actual)Interventional1996-09-30Completed
Phase 2 Historically Controlled Trial of Corticosteroids in Young Boys With Duchenne Muscular Dystrophy[NCT02167217]Phase 225 participants (Actual)Interventional2014-04-17Completed
Duchenne Muscular Dystrophy: Double-blind Randomized Trial to Find Optimum Steroid Regimen[NCT01603407]Phase 3196 participants (Actual)Interventional2013-01-31Completed
Metformin as an Adjunctive Therapy For Transient Hyperglycemia in Patients With Acute Lymphoblastic Leukemia During Induction Chemotherapy[NCT01486043]4 participants (Actual)Interventional2011-12-31Terminated (stopped due to The research project was terminated due to lower than projected patient recruitment within the period of time allowed for the study.)
Effect of Prophylactic Prosthesis Placement With Versus Without Omega-3 at the Umbilical Trocar Level on Surgical Site Infection and Herniation After Laparoscopic Cholecystectomy in Patients With Risk Factors.[NCT04345809]95 participants (Actual)Observational2016-01-31Completed
Sarcopenic Obesity and Associated Risk Factors in Patients Undergone Liver Transplant[NCT05029713]400 participants (Anticipated)Observational2021-05-10Recruiting
NOURISH-T+: A Randomized Control Trial Targeting Parents in Promoting Healthy Eating and Exercise Behaviors in Pediatric Cancer Survivors With Overweight/Obesity[NCT04656496]520 participants (Anticipated)Interventional2020-12-08Recruiting
Spinal Epidural Lipomatosis: a Case Report and Review of the Literature[NCT04622501]1 participants (Actual)Observational2019-06-10Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Bayley III Gross Motor Scaled Score (Change From Baseline to 12 Month)

Bayley III Gross Motor Scaled Score measures motor development. This is normed for typically developing children and follow a bell shaped curve. The scale has mean of 10 +/-3 for children at all ages and is bell shaped. Therefore the two standard deviation range is 16 to 4 with higher values indicated better performance. Lower values have been shown to be common in boys with DMD and it this study the baseline average score was 4.2. (NCT02167217)
Timeframe: One year

Interventionunits on a scale (Mean)
Oral Prednisolone4.8

6 Minute Walk Test

Measures the total distance walked in 6 minutes averaged over all post-baseline follow-up visits through Month 36. (NCT01603407)
Timeframe: Average of Months 3, 6, 12, 18, 24, 30 and 36 visits

Interventionmeters (Least Squares Mean)
Daily Prednisone384.95
Daily Deflazacort384.17
Intermittent Prednisone346.81

Forced Vital Capacity

Forced vital capacity was measured during a spirometry test. Forced expiratory volume (FEV) measures how much air a person can exhale during a forced breath. Forced vital capacity (FVC) is the total amount of air exhaled during the FEV test. (NCT01603407)
Timeframe: Average of Months 3, 6, 12, 18, 24, 30 and 36 visits

Interventionliters (Least Squares Mean)
Daily Prednisone1.4
Daily Deflazacort1.4
Intermittent Prednisone1.5

Fractional Shortening Percent

Measured by trans-thoracic echocardiogram and 12-lead ECG. (NCT01603407)
Timeframe: 36 months

Interventionpercentage of fractional shortening (Least Squares Mean)
Daily Prednisone33.74
Daily Deflazacort34.01
Intermittent Prednisone34.33

Heart Rate

Measured by trans-thoracic echocardiogram and 12-lead ECG. (NCT01603407)
Timeframe: 36 months

Interventionbpm (Least Squares Mean)
Daily Prednisone94.10
Daily Deflazacort93.52
Intermittent Prednisone91.65

Left Ventricular Ejection Fraction Percent

Measured by trans-thoracic echocardiogram and 12-lead ECG. (NCT01603407)
Timeframe: 36 months

Interventionpercentage of ejection fraction (Least Squares Mean)
Daily Prednisone61.88
Daily Deflazacort62.65
Intermittent Prednisone62.45

North Star Ambulatory Assessment (NSAA) Score

"The North Star Ambulatory Assessment (NSAA) is a 17-item rating scale that is used to measure functional motor abilities in ambulant children with Duchenne Muscular Dystrophy (DMD). It is usually used to monitor the progression of the disease and treatment effects.~The activities are graded as follows:~2 - Normal - no obvious modification of activity~1 - Modified method but achieves goal independent of physical assistance from another 0 - Unable to achieve independently This scale is ordinal with 34 as the maximum score indicating fully-independent function." (NCT01603407)
Timeframe: Average of Months 3, 6, 12, 18, 24, 30 and 36 visits

Interventionscore on a scale (Least Squares Mean)
Daily Prednisone23.7
Daily Deflazacort24.0
Intermittent Prednisone20.7

Number of Participants Who Tolerated the Regimen

The number of participants who completed 36 months of follow-up on the originally assigned dosage (for weight) of study medication. (NCT01603407)
Timeframe: 3 years

InterventionParticipants (Count of Participants)
Daily Prednisone36
Daily Deflazacort36
Intermittent Prednisone37

Participant Body Mass Index

(NCT01603407)
Timeframe: 36 months

Interventionkilograms/square meter (Least Squares Mean)
Daily Prednisone18.9
Daily Deflazacort18.3
Intermittent Prednisone18.1

Participant Height

(NCT01603407)
Timeframe: 36 months

Interventioncentimeters (Least Squares Mean)
Daily Prednisone116.8
Daily Deflazacort115.3
Intermittent Prednisone119.9

Participant Weight

(NCT01603407)
Timeframe: 36 months

Interventionkilograms (Least Squares Mean)
Daily Prednisone26.3
Daily Deflazacort24.9
Intermittent Prednisone26.3

PR Interval

Measured by trans-thoracic echocardiogram and 12-lead ECG. (NCT01603407)
Timeframe: 36 months

Interventionmilliseconds (Least Squares Mean)
Daily Prednisone115.59
Daily Deflazacort116.87
Intermittent Prednisone117.90

Quality of Life - Parent

Quality of life was measured by parent/guardian self-report for all children utilizing the PEDSQL measurement tool. This is a 23-question tool. Scores can range from 0 to 100, with higher scores indicating better quality of life for the child. (NCT01603407)
Timeframe: Average of Months 12, 24, and 36 visits

Interventionscore on a scale (Least Squares Mean)
Daily Prednisone64.88
Daily Deflazacort63.71
Intermittent Prednisone61.33

Quality of Life- Child

Quality of life was measured by child self-report in children age 5 and older utilizing the PEDSQL measurement tool. This is a 23-question tool. Scores can range from 0 to 100, with higher scores indicating better quality of life. (NCT01603407)
Timeframe: Average of Months 12, 24, and 36 visits

Interventionscore on a scale (Least Squares Mean)
Daily Prednisone67.39
Daily Deflazacort64.96
Intermittent Prednisone65.07

Range of Motion (Goniometry) of Left Ankle

Range of motion at the ankle joint in dorsiflexion measured in degrees from plantigrade averaged over all post-baseline visits. (NCT01603407)
Timeframe: Average of Months 3, 6, 12, 18, 24, 30 and 36 visits

Interventiondegrees (Mean)
Daily Prednisone4.39
Daily Deflazacort3.29
Intermittent Prednisone2.67

Range of Motion (Goniometry) of Right Ankle

Range of motion at the ankle joint in dorsiflexion measured in degrees from plantigrade averaged over all post-baseline visits. (NCT01603407)
Timeframe: Average of Months 3, 6, 12, 18, 24, 30 and 36 visits

Interventiondegrees (Mean)
Daily Prednisone4.05
Daily Deflazacort2.81
Intermittent Prednisone2.29

Rise From the Floor Velocity

Reciprocal of time to rise from the floor (NCT01603407)
Timeframe: Average of Months 3, 6, 12, 18, 24, 30 and 36 visits

Interventionrise/sec (Least Squares Mean)
Daily Prednisone0.24
Daily Deflazacort0.24
Intermittent Prednisone0.18

Treatment Satisfaction Questionnaire for Medication (TSQM) Global Satisfaction With Treatment Score

The TSQM Global Satisfaction with Treatment is a 14-item questionnaire that ranges from 0 - 100 with higher scores indicating better outcomes. (NCT01603407)
Timeframe: Average of Months 3, 6, 12, 18, 24, 30 and 36 visits

Interventionscore on a scale (Least Squares Mean)
Daily Prednisone71.2
Daily Deflazacort67.8
Intermittent Prednisone65.1

Hemoglobin A1c

(NCT01486043)
Timeframe: At 1 month

Interventionpercent of hemoglobin (Mean)
Metformin and Insulin Therapy4.8

Length of Insulin Therapy (Days)

(NCT01486043)
Timeframe: During the 30 days of induction chemotherapy (plus or minus 2 weeks)

Interventiondays (Mean)
Metformin and Insulin Therapy7.5

Serum Fructosamine Level

(NCT01486043)
Timeframe: At 1 month

InterventionuM (Mean)
Metformin and Insulin Therapy190

Reviews

6 reviews available for prednisone and Obesity

ArticleYear
    Biomaterial investigations in dentistry, 2021, Volume: 8, Issue:1

    Topics: Adult; Alcohol Drinking; Ammonia; Animals; Anti-Inflammatory Agents; Area Under Curve; B-Lymphocytes

2021
    Neuropsychiatrie de l'enfance et de l'adolescence, 2023, Volume: 71, Issue:1

    Topics: Acceptance and Commitment Therapy; Adolescent; Adult; Aged; Aldehydes; Alpinia; Animals; Antibodies,

2023
[Secondary diabetes in childhood].
    Horumon to rinsho. Clinical endocrinology, 1982, Volume: 30, Issue:9

    Topics: Adolescent; Antineoplastic Agents; Asparaginase; Child; Child, Preschool; Diabetes Mellitus; Diabete

1982
Glucocorticoids, glucose metabolism and hypothalamic-pituitary-adrenal axis.
    Advances in experimental medicine and biology, 1984, Volume: 171

    Topics: Addison Disease; Blood Glucose; Cushing Syndrome; Female; Glucocorticoids; Gluconeogenesis; Glucose;

1984
Hypothalamic-pituitary-adrenocortical regulation. A contribution to its assessment, development and disorders in infancy and childhood with special reference to plasma cortisol circadian rhythm.
    Monographs in paediatrics, 1976, Volume: 7

    Topics: 17-Hydroxycorticosteroids; Adrenal Cortex; Adrenal Glands; Adrenocorticotropic Hormone; Anorexia Ner

1976
[Free fatty acids in the serum--regulatory mechanism and clinical significance].
    Zeitschrift fur arztliche Fortbildung, 1969, Mar-01, Volume: 63, Issue:5

    Topics: Adolescent; Adult; Animals; Child; Child, Preschool; Diabetes Mellitus; Diabetes Mellitus, Type 1; D

1969

Trials

8 trials available for prednisone and Obesity

ArticleYear
    Neuropsychiatrie de l'enfance et de l'adolescence, 2023, Volume: 71, Issue:1

    Topics: Acceptance and Commitment Therapy; Adolescent; Adult; Aged; Aldehydes; Alpinia; Animals; Antibodies,

2023
The role of body mass index in survival outcome for lymphoma patients: US intergroup experience.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2014, Volume: 25, Issue:3

    Topics: Antibodies, Monoclonal, Murine-Derived; Antineoplastic Agents; Antineoplastic Combined Chemotherapy

2014
High dose weekly oral prednisone improves strength in boys with Duchenne muscular dystrophy.
    Neuromuscular disorders : NMD, 2002, Volume: 12, Issue:10

    Topics: Administration, Oral; Anti-Inflammatory Agents; Child; Child, Preschool; Drug Administration Schedul

2002
High dose weekly oral prednisone improves strength in boys with Duchenne muscular dystrophy.
    Neuromuscular disorders : NMD, 2002, Volume: 12, Issue:10

    Topics: Administration, Oral; Anti-Inflammatory Agents; Child; Child, Preschool; Drug Administration Schedul

2002
High dose weekly oral prednisone improves strength in boys with Duchenne muscular dystrophy.
    Neuromuscular disorders : NMD, 2002, Volume: 12, Issue:10

    Topics: Administration, Oral; Anti-Inflammatory Agents; Child; Child, Preschool; Drug Administration Schedul

2002
High dose weekly oral prednisone improves strength in boys with Duchenne muscular dystrophy.
    Neuromuscular disorders : NMD, 2002, Volume: 12, Issue:10

    Topics: Administration, Oral; Anti-Inflammatory Agents; Child; Child, Preschool; Drug Administration Schedul

2002
[Clinical study on intervention of liuwei dihuang pill on hormonotherapy in treating nephrotic syndrome].
    Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine, 2005, Volume: 25, Issue:2

    Topics: Adolescent; Adult; Drug Therapy, Combination; Drugs, Chinese Herbal; Female; Follow-Up Studies; Huma

2005
The effects of cyclosporine and prednisone on serum lipid and (apo)lipoprotein levels in renal transplant recipients.
    Journal of the American Society of Nephrology : JASN, 1995, Volume: 5, Issue:12

    Topics: Adult; Apolipoproteins; Arteriosclerosis; Azathioprine; Cholesterol, HDL; Cyclosporine; Female; Graf

1995
Changes in body mass index and prevalence of overweight in survivors of childhood acute lymphoblastic leukemia: role of cranial irradiation.
    Medical and pediatric oncology, 2000, Volume: 35, Issue:2

    Topics: Adolescent; Age Factors; Antineoplastic Combined Chemotherapy Protocols; Body Height; Body Mass Inde

2000
Effect of body weight on the pharmacokinetics of cyclophosphamide in breast cancer patients.
    Cancer chemotherapy and pharmacology, 1987, Volume: 20, Issue:3

    Topics: Administration, Oral; Antineoplastic Combined Chemotherapy Protocols; Body Weight; Breast Neoplasms;

1987
Adjuvant CMFP versus CMFP plus tamoxifen versus observation alone in postmenopausal, node-positive breast cancer patients: three-year results of an Eastern Cooperative Oncology Group study.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1985, Volume: 3, Issue:2

    Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Clinical Trials as Topic; Combined

1985

Other Studies

86 other studies available for prednisone and Obesity

ArticleYear
Stridor Due to Cranial Nerve X Palsy Progressing to Polyneuropathy in a Teenager With COVID-19.
    Pediatrics, 2021, 12-01, Volume: 148, Issue:6

    Topics: Acute Disease; Adolescent; Combined Modality Therapy; COVID-19; Deglutition Disorders; Diagnosis, Di

2021
Intermittent prednisone treatment in mice promotes exercise tolerance in obesity through adiponectin.
    The Journal of experimental medicine, 2022, 05-02, Volume: 219, Issue:5

    Topics: Adipocytes; Adiponectin; Animals; Exercise Tolerance; Mice; Obesity; Prednisone

2022
The long-term (five years) effects of prednisone therapy in children with frequently relapsing nephrotic syndrome: A controlled study of anthropometric parameters and metabolic abnormalities.
    Acta bio-medica : Atenei Parmensis, 2022, 10-26, Volume: 93, Issue:5

    Topics: Child; Cholesterol; Glucose; Humans; Metabolic Syndrome; Nephrotic Syndrome; Obesity; Prednisolone;

2022
AAV induces hepatic necroptosis and carcinoma in diabetic and obese mice dependent on Pebp1 pathway.
    EMBO molecular medicine, 2023, 07-10, Volume: 15, Issue:7

    Topics: Animals; Carcinoma, Hepatocellular; Dependovirus; Diabetes Mellitus; Humans; Inflammation; Liver Neo

2023
Epicardial Adipose Tissue Volume As a Marker of Subclinical Coronary Atherosclerosis in Rheumatoid Arthritis.
    Arthritis & rheumatology (Hoboken, N.J.), 2021, Volume: 73, Issue:8

    Topics: Adipose Tissue; Arthritis, Rheumatoid; Atherosclerosis; Biomarkers; C-Reactive Protein; Case-Control

2021
Characteristics of Hearts at Necropsy in Patients Treated Chronically With Prednisone (The Corticosteroid Heart).
    The American journal of cardiology, 2016, 12-15, Volume: 118, Issue:12

    Topics: Adiposity; Adrenal Cortex Hormones; Adult; Aged; Aged, 80 and over; Autopsy; Case-Control Studies; C

2016
Non-alcoholic steatohepatitis induced by induction chemotherapy for pediatric acute lymphoblastic leukemia.
    International journal of hematology, 2018, Volume: 107, Issue:4

    Topics: Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Biomarkers; Child; Daunorubicin; gamma

2018
Obesity negatively impacts outcome in elderly female patients with aggressive B-cell lymphomas treated with R-CHOP: results from prospective trials of the German high grade non-Hodgkin's lymphoma trial group.
    British journal of haematology, 2018, Volume: 180, Issue:2

    Topics: Age Factors; Aged; Aged, 80 and over; Antibodies, Monoclonal, Murine-Derived; Antineoplastic Combine

2018
Idiopathic intracranial hypertension presenting with isolated unilateral facial nerve palsy: a case report.
    Journal of medical case reports, 2019, Apr-19, Volume: 13, Issue:1

    Topics: Acetazolamide; Adult; Facial Paralysis; Female; Headache; Humans; Magnetic Resonance Imaging; Obesit

2019
Impact on survival and toxicity by duration of weight extremes during treatment for pediatric acute lymphoblastic leukemia: A report from the Children's Oncology Group.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2014, May-01, Volume: 32, Issue:13

    Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Child; Child, Preschool; C

2014
Diffuse large B-cell lymphoma (DLBCL) in the bypassed stomach after obesity surgery.
    Clinical obesity, 2014, Volume: 4, Issue:2

    Topics: Antibodies, Monoclonal, Murine-Derived; Antineoplastic Combined Chemotherapy Protocols; Cyclophospha

2014
Obese non-Hodgkin lymphoma patients tolerate full uncapped doses of chemotherapy with no increase in toxicity, and a similar survival to that seen in nonobese patients.
    Leukemia & lymphoma, 2016, Volume: 57, Issue:11

    Topics: Adult; Aged; Aged, 80 and over; Antibodies, Monoclonal, Murine-Derived; Antineoplastic Combined Chem

2016
Moderating effects of immunosuppressive medications and risk factors for post-operative joint infection following total joint arthroplasty in patients with rheumatoid arthritis or osteoarthritis.
    Seminars in arthritis and rheumatism, 2017, Volume: 46, Issue:4

    Topics: Aged; Allopurinol; Arthritis, Rheumatoid; Arthroplasty, Replacement; Arthroplasty, Replacement, Hip;

2017
The relationship of body mass index and serum testosterone with disease outcomes in men with castration-resistant metastatic prostate cancer.
    Prostate cancer and prostatic diseases, 2009, Volume: 12, Issue:1

    Topics: Aged; Alkaline Phosphatase; Antineoplastic Combined Chemotherapy Protocols; Body Mass Index; Clinica

2009
Prednisone 10 days on/10 days off in patients with Duchenne muscular dystrophy.
    Journal of neurology, 2009, Volume: 256, Issue:5

    Topics: Adolescent; Age Factors; Age of Onset; Akathisia, Drug-Induced; Anti-Inflammatory Agents; Child; Chi

2009
Weight patterns in children with higher risk ALL: A report from the Children's Oncology Group (COG) for CCG 1961.
    Pediatric blood & cancer, 2009, Dec-15, Volume: 53, Issue:7

    Topics: Adolescent; Age Factors; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Body Mass Ind

2009
Environmental endocrine disruptors promote adipogenesis in the 3T3-L1 cell line through glucocorticoid receptor activation.
    Obesity (Silver Spring, Md.), 2010, Volume: 18, Issue:7

    Topics: 3T3-L1 Cells; Adipocytes; Adipogenesis; Animals; Benzhydryl Compounds; Blood Proteins; Cell Differen

2010
Plasma levels of copper, manganese and selenium in an adult population in southern Spain: influence of age, obesity and lifestyle factors.
    The Science of the total environment, 2010, Feb-01, Volume: 408, Issue:5

    Topics: Adult; Age Factors; Antineoplastic Combined Chemotherapy Protocols; Cross-Sectional Studies; Cycloph

2010
Emodin, a natural product, selectively inhibits 11beta-hydroxysteroid dehydrogenase type 1 and ameliorates metabolic disorder in diet-induced obese mice.
    British journal of pharmacology, 2010, Volume: 161, Issue:1

    Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 1; Adrenal Cortex Hormones; Animals; Cell Line; Dexamethas

2010
Homozygosity for the rs9939609T allele of the FTO gene may have protective effect on becoming overweight in survivors of childhood acute lymphoblastic leukaemia.
    Journal of genetics, 2011, Volume: 90, Issue:2

    Topics: Adolescent; Alpha-Ketoglutarate-Dependent Dioxygenase FTO; Antineoplastic Combined Chemotherapy Prot

2011
An unusual case of stroke.
    The neurologist, 2012, Volume: 18, Issue:4

    Topics: Antihypertensive Agents; Diabetes Mellitus, Type 2; Diagnosis, Differential; Diuretics; Female; Furo

2012
[Immunologic determination of ACTH in the venous blood of man in some pathologic situations].
    Bollettino della Societa italiana di biologia sperimentale, 1963, May-15, Volume: 39

    Topics: Adrenocorticotropic Hormone; Arthritis; Arthritis, Rheumatoid; Dexamethasone; Hyperthyroidism; Immun

1963
PRESUMPTIVE ORMOND'S DISEASE: REMISSION FOLLOWING STEROID THERAPY.
    Henry Ford Hospital medical bulletin, 1963, Volume: 11

    Topics: Clinical Laboratory Techniques; Humans; Obesity; Prednisone; Retroperitoneal Fibrosis; Retroperitone

1963
[THE GLUCOSE TOLERANCE CURVE BEFORE AND AFTER PREDNISONE IN THE PERSON WITH NORMAL WEIGHT AND THE OVERWEIGHT PERSON].
    Il Progresso medico, 1963, Feb-15, Volume: 19

    Topics: Glucose; Glucose Tolerance Test; Humans; Obesity; Overweight; Pharmacology; Prednisone

1963
[ON THE PREDNISONE-GLUCOSE TOLERANCE TEST].
    Zeitschrift fur die gesamte innere Medizin und ihre Grenzgebiete, 1964, Jan-01, Volume: 19

    Topics: Diabetes Mellitus; Glucose Tolerance Test; Humans; Obesity; Prednisone

1964
OLIGOMENORRHEA. A DOUBLE BLIND STUDY OF THE EFFECTS OF PREDNISONE AND PACEBO.
    American journal of obstetrics and gynecology, 1964, Jul-01, Volume: 89

    Topics: Amenorrhea; Biomedical Research; Double-Blind Method; Endometrium; Female; Hirsutism; Humans; Hypert

1964
[ON THE PREDNISONE-GLUCOSE TOLERANCE TEST. II].
    Zeitschrift fur die gesamte innere Medizin und ihre Grenzgebiete, 1964, May-15, Volume: 19

    Topics: Adolescent; Birth Weight; Child; Diabetes Mellitus; Diagnosis; Genetics, Medical; Geriatrics; Glucos

1964
[STUDIES OF METABOLIC PROCESSES IN WHITE BLOOD CELLS. II. ON THE PROBLEM OF ENZYME INDUCTION IN METABOLIC CHANGES: ENZYME PATTERNS IN DIABETES MELLITUS, UNDER VARIOUS NUTRITIONAL CONDITIONS AND UNDER THE INFLUENCE OF HORMONAL FACTORS].
    Klinische Wochenschrift, 1964, Nov-15, Volume: 42

    Topics: Diabetes Mellitus; Enzyme Induction; Enzymes; Humans; Leukocyte Count; Leukocytes; Metabolism; Nandr

1964
Increased expression and activity of 11beta-HSD-1 in diabetic islets and prevention with troglitazone.
    Biochemical and biophysical research communications, 2004, Jan-16, Volume: 313, Issue:3

    Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 1; Animals; Animals, Genetically Modified; Blotting, Weste

2004
Development of growth and body mass index after pediatric renal transplantation.
    Pediatric transplantation, 2005, Volume: 9, Issue:4

    Topics: Antibodies, Monoclonal; Basiliximab; Body Height; Body Mass Index; Child; Cyclosporine; Female; Glom

2005
Risk factors for glucocorticoid-induced obesity in children with steroid-sensitive nephrotic syndrome.
    Pediatric nephrology (Berlin, Germany), 2006, Volume: 21, Issue:7

    Topics: Adolescent; Adult; Body Mass Index; Body Size; Child; Child, Preschool; Cross-Sectional Studies; Dru

2006
[Diminishing of glucose tolerance in children with simple obesity].
    Pediatria polska, 1967, Volume: 42, Issue:6

    Topics: Adolescent; Child; Glucose Tolerance Test; Humans; Hyperglycemia; Obesity; Prednisone

1967
[Latent diabetes in children].
    Pediatria polska, 1967, Volume: 42, Issue:4

    Topics: Adolescent; Child; Child, Preschool; Diabetes Mellitus, Type 1; Female; Glucose Tolerance Test; Huma

1967
[Contribution to case finding of prediabetes in obese children from diabetic families].
    Ceskoslovenska pediatrie, 1967, Volume: 22, Issue:8

    Topics: Adolescent; Blood Glucose; Body Weight; Child; Child, Preschool; Diabetes Mellitus; Female; Humans;

1967
Risk factors for hyperglycemia in children with leukemia receiving L-asparaginase and prednisone.
    The Journal of pediatrics, 1981, Volume: 99, Issue:1

    Topics: Adolescent; Adult; Age Factors; Asparaginase; Child; Child, Preschool; Diabetes Mellitus; Down Syndr

1981
Prednisolone disposition in obese men.
    Clinical pharmacology and therapeutics, 1984, Volume: 36, Issue:6

    Topics: Adolescent; Adult; Blood Proteins; Body Weight; Humans; Hydrocortisone; Kinetics; Male; Obesity; Pre

1984
Polymyositis associated with jejunoileal bypass.
    The Journal of rheumatology, 1983, Volume: 10, Issue:4

    Topics: Female; Humans; Ileum; Jejunum; Middle Aged; Myositis; Obesity; Postoperative Complications; Prednis

1983
Plasma lipids in kidney transplanted children and adolescents: influence of pubertal development, dietary intake and steroid therapy.
    European journal of clinical investigation, 1981, Volume: 11, Issue:5

    Topics: Adolescent; Adult; Child; Diet; Female; Humans; Hyperlipidemias; Kidney; Kidney Transplantation; Lip

1981
Comparison of alternate day steroids and daily steroids in renal transplant recipients.
    Proceedings of the Clinical Dialysis and Transplant Forum, 1980, Volume: 10

    Topics: Blood Glucose; Blood Pressure; Body Weight; Creatinine; Graft Rejection; Humans; Hyperglycemia; Hype

1980
Prednisone-induced Munchausen syndrome.
    American journal of diseases of children (1960), 1981, Volume: 135, Issue:9

    Topics: Adolescent; Cushing Syndrome; Female; Humans; Munchausen Syndrome; Obesity; Prednisone

1981
Obesity after successful treatment of acute lymphoblastic leukemia in childhood.
    Pediatric research, 1995, Volume: 38, Issue:1

    Topics: Adolescent; Age Factors; Antineoplastic Agents, Hormonal; Child; Child, Preschool; Dexamethasone; Fe

1995
Greater risk of incisional hernia with morbidly obese than steroid-dependent patients and low recurrence with prefascial polypropylene mesh.
    American journal of surgery, 1996, Volume: 171, Issue:1

    Topics: Abdomen; Colectomy; Colitis, Ulcerative; Fascia; Female; Follow-Up Studies; Gastric Bypass; Hernia,

1996
Nutritional state alterations in children with acute lymphoblastic leukemia during induction and consolidation of chemotherapy.
    Archives of medical research, 1997,Summer, Volume: 28, Issue:2

    Topics: Adolescent; Anthropometry; Antineoplastic Combined Chemotherapy Protocols; Arm; Asparaginase; Body C

1997
The impact of pre-transplant obesity on renal transplant outcomes.
    Clinical transplantation, 1997, Volume: 11, Issue:5 Pt 2

    Topics: Adult; Azathioprine; Body Mass Index; Cadaver; Cyclosporine; Diabetes Mellitus; Female; Glucocortico

1997
Evolution of cardiovascular risk after liver transplantation: a comparison of cyclosporine A and tacrolimus (FK506).
    Liver transplantation and surgery : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society, 1997, Volume: 3, Issue:1

    Topics: Adult; Benzothiadiazines; Blood Glucose; Blood Pressure; Body Weight; Cyclosporine; Diabetes Mellitu

1997
Weight change and obesity after liver transplantation: incidence and risk factors.
    Liver transplantation and surgery : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society, 1998, Volume: 4, Issue:4

    Topics: Adult; Aged; Body Mass Index; Cohort Studies; Cyclosporine; Female; Glucocorticoids; Graft Rejection

1998
Acute interstitial nephritis following treatment with anorectic agents phentermine and phendimetrazine.
    Clinical nephrology, 1998, Volume: 50, Issue:4

    Topics: Acute Disease; Anti-Inflammatory Agents; Appetite Depressants; Creatinine; Female; Follow-Up Studies

1998
Spinal epidural lipomatosis.
    Swiss medical weekly, 2001, Jun-16, Volume: 131, Issue:23-24

    Topics: Epidural Neoplasms; Glucocorticoids; Humans; Lipomatosis; Obesity; Prednisone; Spinal Neoplasms

2001
Intestinal bypass arthritis: association with circulating immune complexes and HLA B27.
    The Journal of rheumatology, 1977,Summer, Volume: 4, Issue:2

    Topics: Adolescent; Arthritis; Female; Histocompatibility Antigens; HLA Antigens; Humans; Immune Complex Dis

1977
Hyperlipidemia in adult, pediatric and diabetic renal transplant recipients.
    The American journal of medicine, 1978, Volume: 64, Issue:4

    Topics: Adolescent; Adult; Blood Glucose; Child; Cholesterol; Creatinine; Diabetes Complications; Drug Admin

1978
Alternate-day prednisone therapy in recipients of renal allografts. Risk and benefits.
    Archives of surgery (Chicago, Ill. : 1960), 1976, Volume: 111, Issue:8

    Topics: Adolescent; Adult; Cataract; Child; Creatinine; Cushing Syndrome; Diabetes Complications; Female; Fe

1976
Hemoglobin AIc levels in insulin-dependent and -independent diabetes mellitus.
    Diabetes, 1976, Volume: 25, Issue:2 SUPPL

    Topics: Adolescent; Adult; Child; Child, Preschool; Cystic Fibrosis; Diabetes Mellitus; Diabetes Mellitus, T

1976
Benign intracranial hypertension.
    Medicine, 1975, Volume: 54, Issue:3

    Topics: Adolescent; Adult; Age Factors; Cerebrospinal Fluid Shunts; Dexamethasone; Female; Follow-Up Studies

1975
[Problems raised by corticoid therapy in children].
    La Revue du praticien, 1975, Mar-11, Volume: 25, Issue:15

    Topics: Adrenal Cortex Hormones; Adrenal Glands; Adrenal Insufficiency; Age Factors; Animals; Chickenpox; Ch

1975
Weber-Christian disease after weight loss.
    Southern medical journal, 1976, Volume: 69, Issue:4

    Topics: Adolescent; Age Factors; Diet, Reducing; Female; Humans; Obesity; Panniculitis, Nodular Nonsuppurati

1976
[Peri-visceral fat infiltration].
    Presse medicale (Paris, France : 1983), 1992, Jun-27, Volume: 21, Issue:24

    Topics: Aged; Bronchitis; Chronic Disease; Ethanol; Humans; Male; Obesity; Prednisone; Tomography, X-Ray Com

1992
Risk factors for coronary artery disease in patients with systemic lupus erythematosus.
    The American journal of medicine, 1992, Volume: 93, Issue:5

    Topics: Adult; Age Factors; Cholesterol; Coronary Disease; Female; Humans; Hypertension; Logistic Models; Lu

1992
Coronary artery disease risk factors in the Johns Hopkins Lupus Cohort: prevalence, recognition by patients, and preventive practices.
    Medicine, 1992, Volume: 71, Issue:5

    Topics: Adolescent; Adult; Baltimore; Cohort Studies; Coronary Disease; Cross-Sectional Studies; Female; Hos

1992
Serum lipid abnormalities in pediatric liver transplant patients.
    Transplantation, 1992, Volume: 53, Issue:1

    Topics: Adolescent; Child; Child, Preschool; Cholesterol; Cyclosporine; Exercise; Female; Humans; Infant; Li

1992
Lipid abnormalities in cyclosporine-prednisone-treated renal transplant recipients.
    Transplantation, 1989, Volume: 48, Issue:1

    Topics: Adult; Cholesterol, LDL; Cyclosporins; Diabetes Mellitus; Female; Humans; Hyperlipidemias; Kidney; K

1989
[Feasibility of CHOP chemotherapy--with special reference to age, diabetes mellitus, liver cirrhosis and obesity].
    Nihon Gan Chiryo Gakkai shi, 1989, Jan-20, Volume: 24, Issue:1

    Topics: Aged; Aged, 80 and over; Aging; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Di

1989
Long-term, small dose prednisone therapy in frequently relapsing nephrotic syndrome of childhood. Effect on remission, statural growth, obesity, and infection rate.
    Clinical pediatrics, 1988, Volume: 27, Issue:8

    Topics: Adolescent; Body Height; Child; Child, Preschool; Female; Humans; Infection Control; Male; Nephrotic

1988
Corticosteroid therapy-induced obesity in children.
    Clinical pediatrics, 1986, Volume: 25, Issue:3

    Topics: Adolescent; Body Weight; Child; Child, Preschool; Female; Humans; Infant; Male; Nephrotic Syndrome;

1986
Granulomatous angiitis presenting with polymyalgia rheumatica and abnormal pituitary function.
    Annals of internal medicine, 1985, Volume: 102, Issue:2

    Topics: Female; Granuloma; Humans; Hypothalamic Diseases; Middle Aged; Obesity; Pituitary Diseases; Polymyal

1985
Differential studies on the mechanism of serum androgen and androgen-binding abnormalities in hirsutism.
    American journal of obstetrics and gynecology, 1973, Dec-01, Volume: 117, Issue:7

    Topics: Androgen Antagonists; Androgens; Beta-Globulins; Dihydrotestosterone; Estrogens, Conjugated (USP); F

1973
Oral contraceptives and carbohydrate metabolism.
    American journal of obstetrics and gynecology, 1968, May-15, Volume: 101, Issue:2

    Topics: Adult; Chlormadinone Acetate; Contraceptives, Oral; Diabetes Mellitus; Dietary Carbohydrates; Estrad

1968
[Chronic viral hepatitis in childhood. 24 cases including 5 sibling pairs].
    Infection, 1973, Volume: 1, Issue:4

    Topics: Adolescent; Agammaglobulinemia; Age Factors; Autoantibodies; Azathioprine; Biopsy; Child; Child, Pre

1973
[Letter: Substitution therapy following surgery of a hypophyseal neoplasm].
    Medizinische Klinik, 1974, Sep-06, Volume: 69, Issue:36

    Topics: Humans; Hypertension; Long-Term Care; Male; Middle Aged; Obesity; Pituitary Neoplasms; Postoperative

1974
[What is guaranteed in the therapy of chronic hepatitis?].
    Der Internist, 1973, Volume: 14, Issue:12

    Topics: Acne Vulgaris; Adrenal Cortex Hormones; Azathioprine; Chronic Disease; Diabetes Mellitus; Gastrointe

1973
Hyperlipidaemia in asthmatic patients receiving long-term steroid therapy.
    British medical journal, 1973, Apr-14, Volume: 2, Issue:5858

    Topics: Adrenocorticotropic Hormone; Adult; Asthma; Cholesterol; Diabetes Mellitus; Female; Humans; Hyperlip

1973
Insulin receptor of liver and fat cell membranes.
    Federation proceedings, 1973, Volume: 32, Issue:8

    Topics: Adipose Tissue; Binding Sites; Cell Membrane; Chemical Phenomena; Chemistry; Chromatography, Affinit

1973
Human growth hormone therapy in hypopituitarism due to tuberculous meningitis.
    Acta paediatrica Scandinavica, 1973, Volume: 62, Issue:3

    Topics: Adolescent; Aminosalicylic Acids; Blood Glucose; Body Height; Calcinosis; Child; Child, Preschool; D

1973
Therapy of sarcoidosis initiated with alternate-day prednisone.
    Journal of the National Medical Association, 1973, Volume: 65, Issue:5

    Topics: Adolescent; Adult; Female; Humans; Male; Middle Aged; Obesity; Prednisolone; Prednisone; Sarcoidosis

1973
[Functional exploration of the endocrine pancreas in infantile essential obesity].
    La Clinica pediatrica, 1968, Volume: 50, Issue:8

    Topics: Adrenal Glands; Child; Glucose Tolerance Test; Humans; Hydrocortisone; Insulin; Islets of Langerhans

1968
[Significance of abnormal fetal developments for the detection of prediabetic state].
    Zentralblatt fur Gynakologie, 1972, Jun-03, Volume: 94, Issue:22

    Topics: Birth Weight; Congenital Abnormalities; Diabetes Mellitus; Embryonic and Fetal Development; Female;

1972
Alternate-day corticosteroid regimen.
    Dermatologica, 1971, Volume: 142, Issue:3

    Topics: 17-Hydroxycorticosteroids; Adolescent; Adrenal Glands; Adult; Aged; Body Weight; Child; Child, Presc

1971
Life-threatening asthma.
    The Journal of allergy, 1968, Volume: 42, Issue:5

    Topics: Acid-Base Equilibrium; Age Factors; Aged; Anti-Bacterial Agents; Asthma; Blood Gas Analysis; Broncho

1968
Effects of obesity, glucocorticoid, and oral contraceptive therapy on plasma glucose and blood pyruvate levels.
    British medical journal, 1970, Jan-17, Volume: 1, Issue:5689

    Topics: Adult; Blood Glucose; Contraceptives, Oral; Female; Glucose Tolerance Test; Humans; Obesity; Prednis

1970
Steroid-induced mediastinal lipomatosis.
    Radiology, 1970, Volume: 96, Issue:3

    Topics: Adipose Tissue; Arthritis; Cushing Syndrome; Humans; Lipomatosis; Male; Mediastinal Diseases; Medias

1970
[Progressive chronic polyarthritis and active body mass].
    Zeitschrift fur die gesamte innere Medizin und ihre Grenzgebiete, 1971, Jan-15, Volume: 26, Issue:2

    Topics: Adipose Tissue; Adult; Arthritis, Rheumatoid; Body Weight; Chloroquine; Creatinine; Humans; Methods;

1971
Polyarthritis in obese patients with intestinal bypass.
    Annals of internal medicine, 1971, Volume: 75, Issue:3

    Topics: Adolescent; Adult; Arthritis; Aspirin; Body Height; Body Weight; Colon; Dehydration; Female; Humans;

1971
Decrease in glucose tolerance in children with obesity.
    Polish medical journal, 1968, Volume: 7, Issue:2

    Topics: Adolescent; Child; Diabetes Mellitus; Diabetes Mellitus, Type 1; Female; Glucose; Glucose Tolerance

1968
Serum lipids and glucose tolerance in subjects with a family history of diabetes mellitus.
    Acta medica Scandinavica, 1965, Volume: 178, Issue:2

    Topics: Cholesterol; Diabetes Mellitus; Fatty Acids; Glucose; Glucose Tolerance Test; Glycerides; Humans; Hy

1965
Polycystic ovarian disease. A report of 301 patients.
    American journal of obstetrics and gynecology, 1965, Dec-01, Volume: 93, Issue:7

    Topics: 17-Ketosteroids; Cysts; Female; Hirsutism; Humans; Infertility, Female; Menstruation Disturbances; O

1965
Plasma NEFA response to a glucose load in patients with diabetes, arteriosclerosis and obesity.
    Metabolism: clinical and experimental, 1966, Volume: 15, Issue:1

    Topics: Adipose Tissue; Arteriosclerosis; Blood; Diabetes Mellitus; Fatty Acids; Glucose; Humans; Obesity; P

1966
[The activity of free fatty acids in the serum of children under noradrenaline].
    Zeitschrift fur Kinderheilkunde, 1966, Volume: 96, Issue:4

    Topics: Adolescent; Blood Glucose; Child; Fatty Acids, Nonesterified; Humans; Leukocyte Count; Norepinephrin

1966