prednisone has been researched along with Neural Tube Defects in 2 studies
Prednisone: A synthetic anti-inflammatory glucocorticoid derived from CORTISONE. It is biologically inert and converted to PREDNISOLONE in the liver.
prednisone : A synthetic glucocorticoid drug that is particularly effective as an immunosuppressant, and affects virtually all of the immune system. Prednisone is a prodrug that is converted by the liver into prednisolone (a beta-hydroxy group instead of the oxo group at position 11), which is the active drug and also a steroid.
Neural Tube Defects: Congenital malformations of the central nervous system and adjacent structures related to defective neural tube closure during the first trimester of pregnancy generally occurring between days 18-29 of gestation. Ectodermal and mesodermal malformations (mainly involving the skull and vertebrae) may occur as a result of defects of neural tube closure. (From Joynt, Clinical Neurology, 1992, Ch55, pp31-41)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Twenty-one days into gestation, the dam of a litter of eight golden retriever puppies was administered prednisone, doxycycline, and tramadol as treatment for immune-mediated polyarthritis." | 3.88 | Multiple midline defects identified in a litter of golden retrievers following gestational administration of prednisone and doxycycline: a case series. ( Gunther-Harrington, CT; Kaplan, JL; Stern, JA; Sutton, JS, 2018) |
| "Advanced follicular lymphoma is incurable with conventional chemotherapy and radiotherapy." | 2.71 | A phase 2 trial of CHOP chemotherapy followed by tositumomab/iodine I 131 tositumomab for previously untreated follicular non-Hodgkin lymphoma: Southwest Oncology Group Protocol S9911. ( Braziel, RM; Fisher, RI; Gaynor, ER; LeBlanc, M; Maloney, DG; Miller, TP; Press, OW; Rivkin, SE; Unger, JM, 2003) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kaplan, JL | 1 |
| Gunther-Harrington, CT | 1 |
| Sutton, JS | 1 |
| Stern, JA | 1 |
| Press, OW | 1 |
| Unger, JM | 1 |
| Braziel, RM | 1 |
| Maloney, DG | 1 |
| Miller, TP | 1 |
| LeBlanc, M | 1 |
| Gaynor, ER | 1 |
| Rivkin, SE | 1 |
| Fisher, RI | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Phase II Pilot Trial of CHOP Followed by Iodine-131-Labeled Monoclonal Anti-B1 Antibody for Treatment of Newly Diagnosed Follicular Non-Hodgkin's Lymphomas[NCT00003784] | Phase 2 | 102 participants (Actual) | Interventional | 1999-05-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 trial available for prednisone and Neural Tube Defects
| Article | Year |
|---|---|
A phase 2 trial of CHOP chemotherapy followed by tositumomab/iodine I 131 tositumomab for previously untreated follicular non-Hodgkin lymphoma: Southwest Oncology Group Protocol S9911.
Topics: Adult; Aged; Antibodies, Monoclonal; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamid | 2003 |
1 other study available for prednisone and Neural Tube Defects
| Article | Year |
|---|---|
Multiple midline defects identified in a litter of golden retrievers following gestational administration of prednisone and doxycycline: a case series.
Topics: Abnormalities, Drug-Induced; Animals; Anti-Bacterial Agents; Anti-Inflammatory Agents; Arthritis; Do | 2018 |