prednisone has been researched along with Myelodysplastic Syndromes in 72 studies
Prednisone: A synthetic anti-inflammatory glucocorticoid derived from CORTISONE. It is biologically inert and converted to PREDNISOLONE in the liver.
prednisone : A synthetic glucocorticoid drug that is particularly effective as an immunosuppressant, and affects virtually all of the immune system. Prednisone is a prodrug that is converted by the liver into prednisolone (a beta-hydroxy group instead of the oxo group at position 11), which is the active drug and also a steroid.
Myelodysplastic Syndromes: Clonal hematopoietic stem cell disorders characterized by dysplasia in one or more hematopoietic cell lineages. They predominantly affect patients over 60, are considered preleukemic conditions, and have high probability of transformation into ACUTE MYELOID LEUKEMIA.
Excerpt | Relevance | Reference |
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"To test the hypothesis that combination treatment with lenalidomide and prednisone will yield a higher erythroid response rate in patients with non-del(5q) lower-risk myelodysplastic syndromes compared to the historical clinical trial data with lenalidomide monotherapy, which reported a 26% transfusion independence rate." | 9.30 | Lenalidomide and Prednisone in Low and Intermediate-1 IPSS Risk, Non-Del(5q) Patients With Myelodysplastic Syndromes: Phase 2 Clinical Trial. ( Al Ali, NH; Cogle, C; Komrokji, RS; Lancet, JE; Lis, AF; Padron, E; Sallman, D; Tinsley, S, 2019) |
" In a randomized study we explored whether prednisone administered from day 0 through 35 along with methotrexate/cyclosporine could improve prevention of acute graft-versus-host disease (GVHD)." | 9.06 | What role for prednisone in prevention of acute graft-versus-host disease in patients undergoing marrow transplants? ( Anasetti, C; Appelbaum, FR; Beatty, P; Doney, K; Martin, P; Pepe, M; Stewart, P; Storb, R; Sullivan, KM; Witherspoon, R, 1990) |
"Lenalidomide therapy represents meaningful progress in the treatment of anemic patients with myelodysplastic syndromes with del(5q)." | 7.88 | Lenalidomide treatment in lower risk myelodysplastic syndromes-The experience of a Czech hematology center. (Positive effect of erythropoietin ± prednisone addition to lenalidomide in refractory or relapsed patients). ( Belickova, M; Cmunt, E; Fuchs, O; Jonasova, A; Michalova, K; Minarik, L; Moudra, A; Neuwirtova, R; Polackova, H; Siskova, M; Stopka, T; Zemanova, Z, 2018) |
"To describe three cases of pericarditis probably related to azacitidine administration in a span of 3 years at our center." | 7.83 | Azacitidine-Induced Pericarditis: A Case Series. ( Gojo, I; Malla, M; Newman, M, 2016) |
"To test the hypothesis that combination treatment with lenalidomide and prednisone will yield a higher erythroid response rate in patients with non-del(5q) lower-risk myelodysplastic syndromes compared to the historical clinical trial data with lenalidomide monotherapy, which reported a 26% transfusion independence rate." | 5.30 | Lenalidomide and Prednisone in Low and Intermediate-1 IPSS Risk, Non-Del(5q) Patients With Myelodysplastic Syndromes: Phase 2 Clinical Trial. ( Al Ali, NH; Cogle, C; Komrokji, RS; Lancet, JE; Lis, AF; Padron, E; Sallman, D; Tinsley, S, 2019) |
" In a randomized study we explored whether prednisone administered from day 0 through 35 along with methotrexate/cyclosporine could improve prevention of acute graft-versus-host disease (GVHD)." | 5.06 | What role for prednisone in prevention of acute graft-versus-host disease in patients undergoing marrow transplants? ( Anasetti, C; Appelbaum, FR; Beatty, P; Doney, K; Martin, P; Pepe, M; Stewart, P; Storb, R; Sullivan, KM; Witherspoon, R, 1990) |
"Lenalidomide therapy represents meaningful progress in the treatment of anemic patients with myelodysplastic syndromes with del(5q)." | 3.88 | Lenalidomide treatment in lower risk myelodysplastic syndromes-The experience of a Czech hematology center. (Positive effect of erythropoietin ± prednisone addition to lenalidomide in refractory or relapsed patients). ( Belickova, M; Cmunt, E; Fuchs, O; Jonasova, A; Michalova, K; Minarik, L; Moudra, A; Neuwirtova, R; Polackova, H; Siskova, M; Stopka, T; Zemanova, Z, 2018) |
"To describe three cases of pericarditis probably related to azacitidine administration in a span of 3 years at our center." | 3.83 | Azacitidine-Induced Pericarditis: A Case Series. ( Gojo, I; Malla, M; Newman, M, 2016) |
"A 62 year-old man with angioimmunoblastic lymphadenopathy was treated with oral prednisone (15 mg/day) and cyclophosphamide." | 3.73 | [Cyclophosphamide-induced neutrophilic disease in a patient with angioimmunoblastic lymphadenopathy and myelodysplastic syndrome]. ( Courville, P; Joly, P; Levesque, H; Sellier, S, 2006) |
" Of eight CML patients in blast crisis (BC) with normal P-gp expression, partial remission was achieved in three and minor response in five after prednisone/vindesine therapy." | 3.69 | Clinical importance of P-glycoprotein-related resistance in leukemia and myelodysplastic syndromes--first experience with their reversal. ( Bartl, R; Beckert, B; Bock, S; Gieseler, F; Gullis, E; Nerl, C; Nüssler, V; Pelka-Fleischer, R; Petrides, PE; Zwierzina, H, 1994) |
"A case of acute nonlymphocytic leukemia (ANLL) occurring 2 years after the diagnosis of multiple myeloma (MM) that had been treated by only one course of melphalan/prednisone chemotherapy is reported." | 3.69 | Trisomy 8 preceding diagnosis of acute nonlymphocytic leukemia by 2 years in a patient with multiple myeloma without cytological evidence of myelodysplasia. ( Hossfeld, DK; Junge, I; Seeger, D; Weh, HJ, 1996) |
"Therapy-related acute myeloid leukemia and myelodysplastic syndromes (t-AML/MDS) represent severe late effects in patients treated for Hodgkin lymphoma (HL)." | 1.40 | Therapy-related acute myeloid leukemia and myelodysplastic syndromes in patients with Hodgkin lymphoma: a report from the German Hodgkin Study Group. ( Behringer, K; Böll, B; Borchmann, P; Diehl, V; Eichenauer, DA; Engert, A; Franklin, J; Fuchs, M; Halbsguth, T; Haverkamp, H; Klimm, B; Rothe, A; Sasse, S; Thielen, I; von Tresckow, B, 2014) |
"To assess therapy-related acute myeloid leukemia/myelodysplastic syndrome (t-AML/MDS) risk in patients treated for Hodgkin lymphoma (HL) on successive generations of Stanford clinical trials." | 1.39 | Risk of therapy-related secondary leukemia in Hodgkin lymphoma: the Stanford University experience over three generations of clinical trials. ( Advani, RH; Balise, R; Greenberg, PL; Hoppe, RT; Horning, SJ; Koontz, MZ; Rosenberg, SA, 2013) |
" Primary therapies were divided into four groups: radiotherapy alone, moderately dosed COPP/ABVD-like chemotherapies for intermediate and advanced stages and BEACOPP escalated." | 1.37 | Impact of first- and second-line treatment for Hodgkin's lymphoma on the incidence of AML/MDS and NHL--experience of the German Hodgkin's Lymphoma Study Group analyzed by a parametric model of carcinogenesis. ( Diehl, V; Engert, A; Franklin, J; Hasenclever, D; Josting, A; Loeffler, M; Scholz, M, 2011) |
"To examine the association of OP with hematologic malignancies and to assess the clinical course of affected patients." | 1.34 | Organizing pneumonia in patients with hematologic malignancies: a steroid-responsive lesion. ( Daniels, CE; Markovic, SN; Myers, JL; Ryu, JH; Utz, JP, 2007) |
"However, erythema nodosum is rarely associated with MDS." | 1.33 | A case of erythema nodosum and serositis associated with myelodysplastic syndrome. ( Ahn, MJ; Choi, JH; Kim, IS; Lee, YY; Oh, HS; Park, YW, 2005) |
" Corticosteroid treatment led to long-lasting renal and hematologic remission, maintained by a small dosage of prednisone." | 1.31 | Glomerular involvement in myelodysplastic syndromes. ( Bogdanović, R; Bunjevacki, G; Kuzmanović, M; Marković-Lipkovski, J; Mićić, D; Nikolić, V; Ognjanović, M; Stajić, N; Stanković, I, 2001) |
"Risk of leukemia was 0." | 1.30 | The risk of acute leukemia in patients treated for Hodgkin's disease is significantly higher aft [see bined modality programs than after chemotherapy alone and is correlated with the extent of radiotherapy and type and duration of chemotherapy: a case-con ( Anselmo, AP; Baroni, CD; Bernasconi, C; Brusamolino, E; Klersy, C; Lazzarino, M; Lunghi, F; Mandelli, F; Maurizi-Enrici, R; Orlandi, E; Pagnucco, G; Santoro, M, 1998) |
"Hodgkin's disease is curable in the majority of patients, although a proportion of patients are resistant to or relapse after initial therapy." | 1.30 | High-dose BEAM chemotherapy with autologous haemopoietic stem cell transplantation for Hodgkin's disease is unlikely to be associated with a major increased risk of secondary MDS/AML. ( Devereux, S; Goldstone, AH; Gregory, W; Hancock, B; Harrison, CN; Hoskin, P; Hudson, GV; Linch, DC; MacMillan, AK; Milligan, D; Newland, AC; Winfield, D, 1999) |
"Myelodysplastic syndromes are a group of clonal hematopoietic stem cell disorders leading to peripheral cytopenias and a high probability of leukemic transformation." | 1.29 | An association of polymyalgia rheumatica with myelodysplastic syndromes. ( Bennett, RM; Kohli, M, 1994) |
"2) Non-Hodgkin's lymphoma has not appeared in any of the patients in this series." | 1.28 | [Second neoplasms as a late complication of the treatment of Hodgkin's disease]. ( Alvarez, A; Colomé, JA; del Potro, E; Díaz Mediavilla, J; González, FA; Martínez, R; Morales, MD; Villegas, A, 1992) |
"20 untreated Hodgkin's disease patients and 1 patient relapsing after radiotherapy (17 stage IIB-IV and 4 stage I-IIA) were given doxorubicin, bleomycin, etoposide and prednisone on a 21-day cycle." | 1.28 | ABEP as primary chemotherapy for Hodgkin's disease. ( Alberto, P; Mermillod, B; Zulian, GB, 1992) |
"A case of acquired haemophilia A presenting with extensive spontaneous bruising and anaemia is reported." | 1.28 | Myelodysplastic syndrome and acquired factor VIII inhibitor with severe subcutaneous haemorrhage. ( Chan, GT; Liang, R; Lin, CK; Liu, HW; Tse, PW, 1991) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 5 (6.94) | 18.7374 |
1990's | 27 (37.50) | 18.2507 |
2000's | 21 (29.17) | 29.6817 |
2010's | 18 (25.00) | 24.3611 |
2020's | 1 (1.39) | 2.80 |
Authors | Studies |
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Fattizzo, B | 1 |
Serpenti, F | 1 |
Versino, F | 1 |
Cassanello, G | 1 |
Cro, LM | 1 |
Barbieri, M | 1 |
Croci, GA | 1 |
Revelli, N | 1 |
Della Porta, MG | 1 |
Barcellini, W | 1 |
Jonasova, A | 1 |
Neuwirtova, R | 1 |
Polackova, H | 1 |
Siskova, M | 1 |
Stopka, T | 1 |
Cmunt, E | 1 |
Belickova, M | 1 |
Moudra, A | 1 |
Minarik, L | 1 |
Fuchs, O | 1 |
Michalova, K | 1 |
Zemanova, Z | 1 |
Hiraga, J | 1 |
Tomita, A | 1 |
Suzuki, N | 1 |
Takagi, Y | 1 |
Narita, M | 1 |
Kagami, Y | 1 |
Komrokji, RS | 1 |
Al Ali, NH | 1 |
Padron, E | 1 |
Cogle, C | 1 |
Tinsley, S | 1 |
Sallman, D | 1 |
Lancet, JE | 1 |
Lis, AF | 1 |
Tobiasson, M | 1 |
Pandzic, T | 1 |
Cavelier, L | 1 |
Sander, B | 1 |
Wahlin, BE | 1 |
Eichenauer, DA | 1 |
Thielen, I | 1 |
Haverkamp, H | 1 |
Franklin, J | 2 |
Behringer, K | 1 |
Halbsguth, T | 1 |
Klimm, B | 1 |
Diehl, V | 2 |
Sasse, S | 1 |
Rothe, A | 1 |
Fuchs, M | 1 |
Böll, B | 1 |
von Tresckow, B | 1 |
Borchmann, P | 1 |
Engert, A | 3 |
Kletzel, M | 1 |
Powers, K | 1 |
Hayes, M | 1 |
Dozzo, M | 1 |
Zaja, F | 1 |
Volpetti, S | 1 |
Chiozzotto, M | 1 |
Puglisi, S | 1 |
Mazzucco, M | 1 |
Perali, G | 1 |
Fanin, R | 1 |
Newman, M | 1 |
Malla, M | 1 |
Gojo, I | 1 |
Ferris, GJ | 1 |
Fabbro, S | 1 |
Gru, A | 1 |
Kaffenberger, J | 1 |
Weed, J | 1 |
Ko, C | 1 |
Stahl, M | 1 |
Much, M | 1 |
Witt, D | 1 |
Zeidan, AM | 1 |
Leventhal, J | 1 |
Yamamoto, K | 1 |
Katayama, Y | 1 |
Shimoyama, M | 1 |
Matsui, T | 1 |
Bauer, K | 1 |
Herbst, C | 1 |
Brillant, C | 1 |
Monsef, I | 1 |
Kluge, S | 1 |
Skoetz, N | 1 |
Piccin, A | 1 |
Cortelazzo, S | 1 |
Rovigatti, U | 1 |
Bourke, B | 1 |
Smith, OP | 1 |
Scholz, M | 1 |
Josting, A | 1 |
Hasenclever, D | 1 |
Loeffler, M | 1 |
Shugarman, IL | 1 |
Schmit, JM | 1 |
Sbicca, JA | 1 |
Wirk, B | 1 |
Paliga, A | 1 |
Shahbazi, N | 1 |
Gonsalves, C | 1 |
Bormanis, J | 1 |
Padmore, R | 1 |
Sadrzadeh, H | 1 |
Hasserjian, R | 1 |
Fathi, AT | 1 |
Koontz, MZ | 1 |
Horning, SJ | 1 |
Balise, R | 1 |
Greenberg, PL | 1 |
Rosenberg, SA | 1 |
Hoppe, RT | 1 |
Advani, RH | 1 |
George, JN | 1 |
Garcia-Manero, G | 1 |
Kantarjian, HM | 1 |
Kornblau, S | 1 |
Estey, E | 1 |
Metayer, C | 1 |
Curtis, RE | 1 |
Vose, J | 2 |
Sobocinski, KA | 1 |
Horowitz, MM | 1 |
Bhatia, S | 1 |
Fay, JW | 1 |
Freytes, CO | 1 |
Goldstein, SC | 1 |
Herzig, RH | 1 |
Keating, A | 1 |
Miller, CB | 1 |
Nevill, TJ | 1 |
Pecora, AL | 1 |
Rizzo, JD | 1 |
Williams, SF | 1 |
Li, CY | 2 |
Travis, LB | 1 |
Weisdorf, DJ | 1 |
Seifert, B | 1 |
Favre, G | 1 |
Lenz, G | 1 |
Dreyling, M | 1 |
Schiegnitz, E | 1 |
Haferlach, T | 1 |
Hasford, J | 1 |
Unterhalt, M | 1 |
Hiddemann, W | 1 |
Kneller, A | 1 |
Cohen, N | 1 |
Berkowicz, M | 1 |
Reichart, M | 1 |
Rosner, E | 1 |
Sokolovski, M | 1 |
Nagler, A | 1 |
Rechavi, G | 1 |
Amariglio, N | 1 |
Trakhtenbrot, L | 1 |
Choi, JH | 1 |
Ahn, MJ | 1 |
Park, YW | 1 |
Oh, HS | 1 |
Lee, YY | 1 |
Kim, IS | 1 |
Bizzoni, L | 1 |
Mazzucconi, MG | 1 |
Gentile, M | 1 |
Santoro, C | 1 |
Bernasconi, S | 1 |
Chiarotti, F | 1 |
Foà, R | 1 |
Mandelli, F | 2 |
Daniels, CE | 1 |
Myers, JL | 1 |
Utz, JP | 1 |
Markovic, SN | 1 |
Ryu, JH | 1 |
Sellier, S | 1 |
Levesque, H | 1 |
Courville, P | 1 |
Joly, P | 1 |
Mobeireek, A | 1 |
Al-Mohareb, F | 1 |
Al-Dayel, F | 1 |
Al-Gazlan, S | 1 |
Alabdely, H | 1 |
Khalid, M | 1 |
Yoshimi, A | 1 |
Baumann, I | 1 |
Führer, M | 1 |
Bergsträsser, E | 1 |
Göbel, U | 1 |
Sykora, KW | 1 |
Klingebiel, T | 1 |
Gross-Wieltsch, U | 1 |
van den Heuvel-Eibrink, MM | 1 |
Fischer, A | 1 |
Nöllke, P | 1 |
Niemeyer, C | 1 |
Chiang, M | 1 |
Fleming, M | 1 |
Shi, YJ | 1 |
Liu, Y | 1 |
Liu, GX | 1 |
Chan, T | 1 |
Juneja, S | 1 |
Wolf, M | 1 |
Januszewicz, E | 1 |
Cooper, I | 1 |
Mittelman, M | 1 |
Lewinski, UH | 1 |
Weiss, H | 1 |
Cohen, AM | 1 |
Djaldetti, M | 1 |
Pick, AI | 1 |
Nüssler, V | 1 |
Pelka-Fleischer, R | 1 |
Zwierzina, H | 1 |
Nerl, C | 1 |
Beckert, B | 1 |
Gullis, E | 1 |
Gieseler, F | 1 |
Bock, S | 1 |
Bartl, R | 1 |
Petrides, PE | 1 |
Anderson, JR | 1 |
Kessinger, A | 1 |
Kohli, M | 1 |
Bennett, RM | 1 |
Dhodapkar, MV | 1 |
Lust, JA | 1 |
Tefferi, A | 1 |
Phyliky, RL | 1 |
Carsuzaa, F | 1 |
Marlier, S | 1 |
Jaubert, D | 1 |
Weh, HJ | 1 |
Seeger, D | 1 |
Junge, I | 1 |
Hossfeld, DK | 1 |
Mok, CC | 1 |
Lau, CS | 1 |
Kumana, CR | 1 |
Hubscher, O | 1 |
Vilches, A | 1 |
Solmesky, S | 1 |
Riveros, D | 1 |
Rodríguez García, JA | 1 |
Gil García, S | 1 |
Biesma, DH | 1 |
van den Tweel, JG | 1 |
Verdonck, LF | 1 |
Corti, C | 1 |
Theodore, C | 1 |
Bayle, C | 1 |
Rougier, P | 1 |
Nasr, F | 1 |
Cosset, JM | 1 |
Girinsky, T | 1 |
Hayat, M | 1 |
Ribrag, V | 1 |
Blanco, R | 1 |
Gonzalez-Gay, MA | 1 |
Ibañez, D | 1 |
Lopez-Viana, A | 1 |
Ferran, C | 1 |
Regueira, A | 1 |
Gonzalez-Vela, C | 1 |
Rodríguez, JN | 1 |
Fernández-Jurado, A | 1 |
Martino, ML | 1 |
Diéguez, JC | 1 |
Moreno, MV | 1 |
Quesada, JA | 1 |
Polo, B | 1 |
Cañavate, M | 1 |
Amian, A | 1 |
Prados, D | 1 |
Boone, LI | 1 |
Knauer, KW | 1 |
Rapp, SW | 1 |
Stewart, JF | 1 |
Modiano, JF | 1 |
Brusamolino, E | 1 |
Anselmo, AP | 1 |
Klersy, C | 1 |
Santoro, M | 1 |
Orlandi, E | 1 |
Pagnucco, G | 1 |
Lunghi, F | 1 |
Maurizi-Enrici, R | 1 |
Baroni, CD | 1 |
Lazzarino, M | 1 |
Bernasconi, C | 1 |
Harrison, CN | 1 |
Gregory, W | 1 |
Hudson, GV | 1 |
Devereux, S | 1 |
Goldstone, AH | 1 |
Hancock, B | 1 |
Winfield, D | 1 |
MacMillan, AK | 1 |
Hoskin, P | 1 |
Newland, AC | 1 |
Milligan, D | 1 |
Linch, DC | 1 |
Takeshita, A | 1 |
Ohno, R | 1 |
Reinhold-Keller, E | 1 |
Beuge, N | 1 |
Latza, U | 1 |
de Groot, K | 1 |
Rudert, H | 1 |
Nölle, B | 1 |
Heller, M | 1 |
Gross, WL | 1 |
Sadek, I | 1 |
Zayed, E | 1 |
Hayne, O | 1 |
Fernandez, L | 1 |
Litvak, D | 1 |
Kirsner, RS | 1 |
Pakdaman, NN | 1 |
Federman, DG | 1 |
Funato, K | 1 |
Kuriyama, Y | 1 |
Uchida, Y | 1 |
Suzuki, A | 1 |
Miyazawa, K | 1 |
Ohyashiki, K | 1 |
Bogdanović, R | 1 |
Kuzmanović, M | 1 |
Marković-Lipkovski, J | 1 |
Ognjanović, M | 1 |
Mićić, D | 1 |
Stanković, I | 1 |
Stajić, N | 1 |
Nikolić, V | 1 |
Bunjevacki, G | 1 |
Paira, S | 1 |
Graf, C | 1 |
Roverano, S | 1 |
Rossini, J | 1 |
Morales, MD | 1 |
González, FA | 1 |
Villegas, A | 1 |
del Potro, E | 1 |
Díaz Mediavilla, J | 1 |
Martínez, R | 1 |
Alvarez, A | 1 |
Colomé, JA | 1 |
Zulian, GB | 1 |
Mermillod, B | 1 |
Alberto, P | 1 |
Blazsek, I | 3 |
Musset, M | 2 |
Boulé, D | 1 |
Labat, ML | 3 |
Bringuier, MF | 1 |
Comisso, M | 3 |
Le Maignan, C | 1 |
Ribaud, P | 1 |
Mathé, G | 3 |
Misset, JL | 3 |
George, SW | 1 |
Newman, ED | 1 |
Komiya, I | 1 |
Tanoue, K | 1 |
Kakinuma, K | 1 |
Kaneda, M | 1 |
Shinohara, T | 1 |
Kuriya, S | 1 |
Nomura, T | 1 |
Saito, Y | 1 |
Jacoby, RF | 1 |
Brasitus, TA | 1 |
Lin, CK | 1 |
Liang, R | 1 |
Liu, HW | 1 |
Tse, PW | 1 |
Chan, GT | 1 |
Farabos, C | 1 |
Goldschmidt, E | 2 |
Benavides, M | 2 |
Wang, ZY | 1 |
Storb, R | 1 |
Pepe, M | 1 |
Anasetti, C | 1 |
Appelbaum, FR | 1 |
Beatty, P | 1 |
Doney, K | 1 |
Martin, P | 1 |
Stewart, P | 1 |
Sullivan, KM | 1 |
Witherspoon, R | 1 |
Stratton, JR | 1 |
Ballem, PJ | 1 |
Gernsheimer, T | 1 |
Cerqueira, M | 1 |
Slichter, SJ | 1 |
Iurlo, A | 1 |
Mecucci, C | 1 |
Van Orshoven, A | 1 |
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Boogaerts, M | 1 |
Van den Berghe, H | 1 |
Machover, D | 1 |
Ceresi, E | 1 |
Canon, C | 1 |
Sizoo, W | 1 |
Hagenbeek, A | 1 |
Löwenberg, B | 1 |
Blayney, DW | 1 |
Longo, DL | 1 |
Young, RC | 1 |
Greene, MH | 1 |
Hubbard, SM | 1 |
Postal, MG | 1 |
Duffey, PL | 1 |
DeVita, VT | 1 |
Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
---|---|---|---|---|---|---|---|
An Exploratory Phase II, Multicenter, Open-label Trial Evaluating the Activity and Tolerability of FK228 in Androgen Independent Metastatic Prostate Cancer Patients With Rising PSA[NCT00106418] | Phase 2 | 35 participants (Actual) | Interventional | 2003-05-07 | Completed | ||
A Randomized Trial of Recombinant Humanized Anti-IL-2 Receptor Antibody (Daclizumab) Versus Antithymocyte Globulin (ATG) to Treat the Cytopenia of Myelodysplastic Syndrome (MDS)[NCT00072969] | Phase 2 | 132 participants | Interventional | 2003-11-30 | Completed | ||
A Pilot Study of Alemtuzumab (Campath[R]) in Patients With Myelodysplastic Syndrome (MDS)[NCT00217594] | Phase 2 | 40 participants (Actual) | Interventional | 2005-07-21 | Completed | ||
An Open Label Pilot Study Examining the Use of Rituximab in Patients With Wegener's Granulomatosis Who Have Experienced Disease Relapse on Standard Therapies[NCT00072592] | Phase 1 | 10 participants | Interventional | 2003-10-31 | Completed | ||
A Randomized Trial Examining the Use of Daclizumab in Wegener's Granulomatosis[NCT00040248] | Phase 2 | 75 participants | Interventional | 2002-06-30 | Completed | ||
[information is prepared from clinicaltrials.gov, extracted Sep-2024] |
"Response to treatment at 3 months after the first dose of alemtuzumab. The parameters for hematologic improvement (HI) and complete response (CR) were defined according to the International Working Group (IWG) criteria. The IWG criteria for HI define specific responses of cytopenias in the 3 hematopoietic lineages: erythroid (HI-E), platelet (HI-P), and neutrophil (HI-N).7 The HIs are measured in patients with pretreatment abnormal values: hemoglobin level less than 110 g/L (11 g/dL) or RBC-transfusion dependence, platelet count less than 100 × 109/L or platelet-transfusion dependence, absolute neutrophil count (ANC) less than 1.0 × 109/L.~The parameters for CR include less than 5% marrow blasts without evidence of dysplasia and normalization of peripheral blood counts, including a hemoglobin level of 110 g/L (11 g/dL) or more (in patients not receiving erythropoietin or transfusions), a neutrophil count of 1.5 × 109/L or more, and a platelet count of 100 × 109/L." (NCT00217594)
Timeframe: 3 months
Intervention | Participants (Count of Participants) |
---|---|
Alemtuzumab | 21 |
4 reviews available for prednisone and Myelodysplastic Syndromes
Article | Year |
---|---|
Xanthomatized Neutrophilic Dermatosis in a Patient With Myelodysplastic Syndrome.
Topics: Biopsy, Needle; Colchicine; Dapsone; Drug Therapy, Combination; Follow-Up Studies; Humans; Immunohis | 2017 |
Therapy-related myelodysplastic/myeloproliferative neoplasms with del(5q) and t(1;11)(p32;q23) lacking MLL rearrangement.
Topics: Aged; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow | 2010 |
[New combination therapies in hematological malignancies].
Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Murine-Derived; Antineoplastic Combined Chemotherapy | 2000 |
Seronegative inflammatory arthritis in the myelodysplastic syndromes.
Topics: Aged; Arthritis; Female; Humans; Male; Myelodysplastic Syndromes; Prednisone; Prospective Studies; S | 1992 |
4 trials available for prednisone and Myelodysplastic Syndromes
Article | Year |
---|---|
Lenalidomide and Prednisone in Low and Intermediate-1 IPSS Risk, Non-Del(5q) Patients With Myelodysplastic Syndromes: Phase 2 Clinical Trial.
Topics: Administration, Oral; Aged; Anemia; Dose-Response Relationship, Drug; Drug Administration Schedule; | 2019 |
Moderate increase of secondary hematologic malignancies after myeloablative radiochemotherapy and autologous stem-cell transplantation in patients with indolent lymphoma: results of a prospective randomized trial of the German Low Grade Lymphoma Study Gro
Topics: Acute Disease; Adult; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Cyc | 2004 |
[Integrated Chinese and western medicinal treatment on systemic lupus erythematosus characterized by hypoplastic bone marrow].
Topics: Adult; Cyclophosphamide; Drug Therapy, Combination; Drugs, Chinese Herbal; Female; gamma-Globins; Hu | 2007 |
What role for prednisone in prevention of acute graft-versus-host disease in patients undergoing marrow transplants?
Topics: Acute Disease; Anemia, Aplastic; Bone Marrow Transplantation; Chronic Disease; Clinical Trials as To | 1990 |
64 other studies available for prednisone and Myelodysplastic Syndromes
Article | Year |
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Use of steroids in the management of low-risk myelodysplastic syndromes with autoimmune features.
Topics: Aged; Anemia, Hemolytic, Autoimmune; Autoantibodies; Humans; Myelodysplastic Syndromes; Prednisone; | 2023 |
Lenalidomide treatment in lower risk myelodysplastic syndromes-The experience of a Czech hematology center. (Positive effect of erythropoietin ± prednisone addition to lenalidomide in refractory or relapsed patients).
Topics: Aged; Aged, 80 and over; Chromosomes, Human, Pair 5; Czech Republic; Erythropoietin; Female; Genes, | 2018 |
Partial restoration of CD20 protein expression and rituximab sensitivity after treatment with azacitidine in CD20-negative transformed diffuse large B cell lymphoma after using rituximab.
Topics: Antigens, CD20; Antigens, Neoplasm; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemoth | 2018 |
Angioimmunoblastic T-cell lymphoma and myelodysplastic syndrome with mutations in
Topics: Aged, 80 and over; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; | 2019 |
Therapy-related acute myeloid leukemia and myelodysplastic syndromes in patients with Hodgkin lymphoma: a report from the German Hodgkin Study Group.
Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cyclophosphamide | 2014 |
Scurvy: a new problem for patients with chronic GVHD involving mucous membranes; an easy problem to resolve.
Topics: Administration, Oral; Adolescent; Adult; Ascorbic Acid; Ascorbic Acid Deficiency; Child; Chronic Dis | 2014 |
Two cases of concomitant diffuse large B-cell lymphoma and myelodysplastic syndrome.
Topics: Antibodies, Monoclonal, Murine-Derived; Antineoplastic Combined Chemotherapy Protocols; Cyclophospha | 2014 |
Azacitidine-Induced Pericarditis: A Case Series.
Topics: Aged; Antimetabolites, Antineoplastic; Azacitidine; Chest Pain; Combined Modality Therapy; Diagnosis | 2016 |
Reactive granulomatous dermatitis presenting as subcutaneous nodules and cords in a patient with advanced myelodysplastic syndrome.
Topics: Aged; Blood Transfusion; Comorbidity; Fatal Outcome; Female; Granuloma; Histiocytes; Humans; Lenalid | 2017 |
Eleventh biannual report of the Cochrane Haematological Malignancies Group: Focus on Hodgkin lymphoma.
Topics: Anemia; Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Bendamustine Hydrochloride; Ble | 2010 |
Immunosuppressive treatments in Crohn's disease induce myelodysplasia and leukaemia.
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Budesonide; Chromosomes, Human, Pair 7; | 2010 |
Impact of first- and second-line treatment for Hodgkin's lymphoma on the incidence of AML/MDS and NHL--experience of the German Hodgkin's Lymphoma Study Group analyzed by a parametric model of carcinogenesis.
Topics: Algorithms; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cyclophosphamide; Dacarbazine | 2011 |
Easily missed extracutaneous manifestation of malignancy-associated Sweet's syndrome: systemic inflammatory response syndrome.
Topics: Aged; Fatal Outcome; Humans; Male; Methylprednisolone; Myelodysplastic Syndromes; Prednisone; Sweet | 2011 |
Trilineage myelodysplasia and hemophagocytosis associated with systemic lupus erythematosus.
Topics: Acute Kidney Injury; Adult; Blood Component Transfusion; Bone Marrow; Cell Lineage; Combined Modalit | 2012 |
Pure erythroid leukemia evolving from a therapy-related myelodysplastic syndrome secondary to treatment for chronic lymphocytic leukemia.
Topics: Abnormal Karyotype; Aged; Antineoplastic Combined Chemotherapy Protocols; Cladribine; Cyclophosphami | 2013 |
Risk of therapy-related secondary leukemia in Hodgkin lymphoma: the Stanford University experience over three generations of clinical trials.
Topics: Academic Medical Centers; Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Californ | 2013 |
Idiopathic thrombocytopenic purpura and myelodysplastic syndrome: distinct entities or overlapping syndromes?
Topics: Aged; Autoimmune Diseases; Bone Marrow; Clone Cells; Diagnosis, Differential; Disease Progression; D | 2002 |
Therapy-related myelodysplastic syndrome or acute myelogenous leukemia in patients with acute promyelocytic leukemia (APL).
Topics: Adult; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Female; Humans; Leukem | 2002 |
Myelodysplastic syndrome and acute myeloid leukemia after autotransplantation for lymphoma: a multicenter case-control study.
Topics: Acute Disease; Adolescent; Adult; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemoth | 2003 |
[Pancytopenia after viral infection in St. n. malignant lymphoma].
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Combined Modality The | 2003 |
Acquisition of a Ph chromosome with minor BCR/ABL fusion in treatment-related myelodysplastic syndrome with chromosome 7 abnormalities in a patient treated for Hodgkin disease.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Chromosome Aberrations; Chromosome | 2005 |
A case of erythema nodosum and serositis associated with myelodysplastic syndrome.
Topics: Adult; Biopsy; Diagnosis, Differential; Erythema Nodosum; Female; Follow-Up Studies; Glucocorticoids | 2005 |
Idiopathic thrombocytopenic purpura (ITP) in the elderly: clinical course in 178 patients.
Topics: Aged; Aged, 80 and over; Autoimmune Diseases; Disease Progression; Drug Evaluation; Female; Hemorrha | 2006 |
Organizing pneumonia in patients with hematologic malignancies: a steroid-responsive lesion.
Topics: Acute Disease; Adult; Aged; Biopsy; Bronchi; Cryptogenic Organizing Pneumonia; Diagnosis, Differenti | 2007 |
[Cyclophosphamide-induced neutrophilic disease in a patient with angioimmunoblastic lymphadenopathy and myelodysplastic syndrome].
Topics: Cyclophosphamide; Glucocorticoids; Humans; Immunoblastic Lymphadenopathy; Immunosuppressive Agents; | 2006 |
Obliterative bronchiolitis in a patient with myelodysplastic syndrome before bone marrow transplantation.
Topics: Adolescent; Bone Marrow Transplantation; Bronchiolitis Obliterans; Fatal Outcome; Female; Glucocorti | 2007 |
Immunosuppressive therapy with anti-thymocyte globulin and cyclosporine A in selected children with hypoplastic refractory cytopenia.
Topics: Antilymphocyte Serum; Blood Transfusion; Child; Combined Modality Therapy; Cyclosporine; Disease Pro | 2007 |
The pseudo-Pelger-Huët anomaly in pyoderma gangrenosum associated with myelodysplastic syndrome.
Topics: Administration, Oral; Administration, Topical; Aged, 80 and over; Fatal Outcome; Glucocorticoids; Hu | 2007 |
Secondary myelodysplastic syndrome following bone marrow transplantation: report of two cases.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Bone Marrow Transplantation; Combi | 1994 |
Secondary myelodysplastic syndrome in multiple myeloma--a study of nine patients with an attempt to detect myeloma patients at risk.
Topics: Aged; Female; Humans; Israel; Leukemia, Myeloid, Acute; Male; Melphalan; Middle Aged; Multiple Myelo | 1994 |
Clinical importance of P-glycoprotein-related resistance in leukemia and myelodysplastic syndromes--first experience with their reversal.
Topics: Adult; Antibodies, Monoclonal; ATP Binding Cassette Transporter, Subfamily B, Member 1; Base Sequenc | 1994 |
Myelodysplastic syndrome after autologous transplant for lymphoma.
Topics: Antineoplastic Combined Chemotherapy Protocols; Hematopoietic Stem Cell Transplantation; Hodgkin Dis | 1994 |
An association of polymyalgia rheumatica with myelodysplastic syndromes.
Topics: Aged; Blood Cell Count; Bone Marrow; Female; Humans; Methotrexate; Middle Aged; Myelodysplastic Synd | 1994 |
Clinical spectrum of clonal proliferations of T-large granular lymphocytes: a T-cell clonopathy of undetermined significance?
Topics: Adult; Aged; Aged, 80 and over; Anemia, Aplastic; Arthritis, Rheumatoid; Blotting, Southern; Bone Ma | 1994 |
[Post-transfusion cutaneous vasculitis in myelodysplastic syndrome].
Topics: Aged; Humans; Male; Myelodysplastic Syndromes; Prednisone; Transfusion Reaction; Vasculitis, Leukocy | 1993 |
Trisomy 8 preceding diagnosis of acute nonlymphocytic leukemia by 2 years in a patient with multiple myeloma without cytological evidence of myelodysplasia.
Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Chromosomes, H | 1996 |
Polymyalgia rheumatica as the rheumatological manifestation of myelodysplastic syndrome in a Chinese patient.
Topics: China; Female; Humans; Middle Aged; Myelodysplastic Syndromes; Polymyalgia Rheumatica; Prednisone | 1996 |
Polymyalgia rheumatica in patients with myelodysplastic syndromes.
Topics: Aged; Aged, 80 and over; Fatal Outcome; Glucocorticoids; Humans; Male; Myelodysplastic Syndromes; Po | 1996 |
[Erythroblastopenia associated with a myelodysplastic syndrome].
Topics: Aged; Bone Marrow; Humans; Immunosuppressive Agents; Myelodysplastic Syndromes; Prednisone; Red-Cell | 1996 |
Immunosuppressive therapy for hypoplastic myelodysplastic syndrome.
Topics: Antilymphocyte Serum; Cyclosporine; Female; Humans; Immunosuppressive Agents; Male; Middle Aged; Mye | 1997 |
Immunosuppressive therapy for hypoplastic myelodysplastic syndrome.
Topics: Antilymphocyte Serum; Cyclosporine; Female; Humans; Immunosuppressive Agents; Male; Middle Aged; Mye | 1997 |
Immunosuppressive therapy for hypoplastic myelodysplastic syndrome.
Topics: Antilymphocyte Serum; Cyclosporine; Female; Humans; Immunosuppressive Agents; Male; Middle Aged; Mye | 1997 |
Immunosuppressive therapy for hypoplastic myelodysplastic syndrome.
Topics: Antilymphocyte Serum; Cyclosporine; Female; Humans; Immunosuppressive Agents; Male; Middle Aged; Mye | 1997 |
High incidence of secondary myelodysplastic syndromes following PROMACE-MOPP and involved field radiotherapy for localized gastric non-Hodgkin's lymphomas.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Cyclophosphamide; Doxorubi | 1996 |
Henoch-Schönlein purpura as clinical presentation of a myelodysplastic syndrome.
Topics: Adult; Humans; IgA Vasculitis; Male; Myelodysplastic Syndromes; Prednisone | 1997 |
[Acute myeloid leukemia in those over 70 years of age. Experience using low-dose ara-C treatment].
Topics: Acute Disease; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Antineoplastic Combined Che | 1998 |
Use of human recombinant erythropoietin and prednisone for treatment of myelodysplastic syndrome with erythroid predominance in a dog.
Topics: Animals; Blood Transfusion; Dog Diseases; Dogs; Drug Therapy, Combination; Erythroid Precursor Cells | 1998 |
The risk of acute leukemia in patients treated for Hodgkin's disease is significantly higher aft [see bined modality programs than after chemotherapy alone and is correlated with the extent of radiotherapy and type and duration of chemotherapy: a case-con
Topics: Abdomen; Actuarial Analysis; Acute Disease; Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; | 1998 |
High-dose BEAM chemotherapy with autologous haemopoietic stem cell transplantation for Hodgkin's disease is unlikely to be associated with a major increased risk of secondary MDS/AML.
Topics: Acute Disease; Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carmustine; | 1999 |
An interdisciplinary approach to the care of patients with Wegener's granulomatosis: long-term outcome in 155 patients.
Topics: Adolescent; Adult; Aged; Cohort Studies; Cyclophosphamide; Cystitis; Female; Granulomatosis with Pol | 2000 |
An interdisciplinary approach to the care of patients with Wegener's granulomatosis: long-term outcome in 155 patients.
Topics: Adolescent; Adult; Aged; Cohort Studies; Cyclophosphamide; Cystitis; Female; Granulomatosis with Pol | 2000 |
An interdisciplinary approach to the care of patients with Wegener's granulomatosis: long-term outcome in 155 patients.
Topics: Adolescent; Adult; Aged; Cohort Studies; Cyclophosphamide; Cystitis; Female; Granulomatosis with Pol | 2000 |
An interdisciplinary approach to the care of patients with Wegener's granulomatosis: long-term outcome in 155 patients.
Topics: Adolescent; Adult; Aged; Cohort Studies; Cyclophosphamide; Cystitis; Female; Granulomatosis with Pol | 2000 |
Prolonged complete remission of myelodysplastic syndrome treated with danazol, retinoic acid and low-dose prednisone.
Topics: Antineoplastic Agents; Danazol; Drug Therapy, Combination; Estrogen Antagonists; Female; Humans; Mid | 2000 |
Pyoderma gangrenosum and myelodysplastic syndrome.
Topics: Anemia, Refractory; Anemia, Sideroblastic; Bone Marrow Examination; Glucocorticoids; Hematocrit; Hum | 2000 |
Myelodysplastic syndrome accompanied by Addison's disease and multiple autoimmune phenomena: steroid therapy resolved cytopenias and all immune disorders.
Topics: Addison Disease; Aged; Aged, 80 and over; Anemia, Hemolytic, Autoimmune; Anti-Inflammatory Agents; B | 2001 |
Glomerular involvement in myelodysplastic syndromes.
Topics: Child; Female; Glucocorticoids; Humans; Infant; Kidney Glomerulus; Myelodysplastic Syndromes; Nephro | 2001 |
Remitting seronegative symmetrical synovitis with pitting oedema: a study of 12 cases.
Topics: Adenocarcinoma; Aged; Aged, 80 and over; Antineoplastic Agents; Colectomy; Colorectal Neoplasms; Ede | 2002 |
[Second neoplasms as a late complication of the treatment of Hodgkin's disease].
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Carcinom | 1992 |
ABEP as primary chemotherapy for Hodgkin's disease.
Topics: Aclarubicin; Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cytarabin | 1992 |
Combined differentiation therapy in myelodysplastic syndrome with retinoid acid, 1 alpha,25 dihydroxyvitamin D3, and prednisone.
Topics: Bone Marrow; Calcitriol; Cell Differentiation; Cells, Cultured; Drug Therapy, Combination; Humans; L | 1992 |
Superoxide anion hyperproduction by neutrophils in a case of myelodysplastic syndrome. Association with Sweet's syndrome and interstitial pneumonia.
Topics: Dermatitis; Humans; Male; Middle Aged; Myelodysplastic Syndromes; Myristic Acid; Myristic Acids; Neu | 1991 |
Myelodysplastic syndrome and pancytopenia in a patient with non-A, non-B chronic active hepatitis.
Topics: Aged; Hepatitis C; Hepatitis, Chronic; Humans; Male; Myelodysplastic Syndromes; Pancytopenia; Predni | 1991 |
Myelodysplastic syndrome and acquired factor VIII inhibitor with severe subcutaneous haemorrhage.
Topics: Aged; Anemia, Sideroblastic; Bone Marrow; Factor VIII; Female; Hemophilia A; Hemorrhage; Humans; Mye | 1991 |
Retinoic acid in mono- or combined differentiation therapy of myelodysplasia and acute promyelocytic leukemia.
Topics: Bone Marrow; Calcitriol; Cells, Cultured; Drug Therapy, Combination; Humans; Leukemia, Promyelocytic | 1991 |
Platelet destruction in autoimmune thrombocytopenic purpura: kinetics and clearance of indium-111-labeled autologous platelets.
Topics: Autoimmune Diseases; Blood Platelets; Cell Survival; Humans; Indium Radioisotopes; Isotope Labeling; | 1989 |
The karyotype in secondary hematologic disorders after treatment for Hodgkin's disease. A study of 19 patients.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Chromosome Aberrations; Female; Hodgkin Disea | 1988 |
Excess of lympho-reticular cell complexes in the bone marrow linked to T cell mediated dysmyelopoiesis.
Topics: Adult; Bone Marrow; Cells, Cultured; Female; Humans; Microscopy, Electron; Myelodysplastic Syndromes | 1986 |
[Myelodysplastic syndromes: a group of preleukemic disorders].
Topics: Acute Disease; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Female; Humans; Leukemia | 1987 |
Decreasing risk of leukemia with prolonged follow-up after chemotherapy and radiotherapy for Hodgkin's disease.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Combined Modality Therapy; | 1987 |