prednisone has been researched along with Motor Neuron Disease in 7 studies
Prednisone: A synthetic anti-inflammatory glucocorticoid derived from CORTISONE. It is biologically inert and converted to PREDNISOLONE in the liver.
prednisone : A synthetic glucocorticoid drug that is particularly effective as an immunosuppressant, and affects virtually all of the immune system. Prednisone is a prodrug that is converted by the liver into prednisolone (a beta-hydroxy group instead of the oxo group at position 11), which is the active drug and also a steroid.
Motor Neuron Disease: Diseases characterized by a selective degeneration of the motor neurons of the spinal cord, brainstem, or motor cortex. Clinical subtypes are distinguished by the major site of degeneration. In AMYOTROPHIC LATERAL SCLEROSIS there is involvement of upper, lower, and brainstem motor neurons. In progressive muscular atrophy and related syndromes (see MUSCULAR ATROPHY, SPINAL) the motor neurons in the spinal cord are primarily affected. With progressive bulbar palsy (BULBAR PALSY, PROGRESSIVE), the initial degeneration occurs in the brainstem. In primary lateral sclerosis, the cortical neurons are affected in isolation. (Adams et al., Principles of Neurology, 6th ed, p1089)
Excerpt | Relevance | Reference |
---|---|---|
"Patients with amyotrophic lateral sclerosis failed to improve irrespective of laboratory findings." | 2.67 | Immunosuppressive treatment of motor neuron syndromes. Attempts to distinguish a treatable disorder. ( Amato, AA; Barohn, RJ; Jackson, CE; Kissel, JT; Lynn, DJ; Mendell, JR; Rammohan, KW; Sahenk, Z; Tan, E; Warmolts, JR, 1994) |
"Although isolated lower motor neuron disease has been reported as a paraneoplastic complication, it has not been previously described, in association with anti-Hu antibody." | 1.29 | Motor neuron disease: a paraneoplastic process associated with anti-hu antibody and small-cell lung carcinoma. ( Berger, JR; Petito, C; Snodgrass, S; Verma, A, 1996) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 5 (71.43) | 18.2507 |
2000's | 2 (28.57) | 29.6817 |
2010's | 0 (0.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Sinno, DD | 1 |
Darras, BT | 1 |
Yamout, BI | 1 |
Rebeiz, JG | 1 |
Mikati, MA | 1 |
Tanaka, M | 1 |
Tan, E | 1 |
Lynn, DJ | 1 |
Amato, AA | 1 |
Kissel, JT | 1 |
Rammohan, KW | 1 |
Sahenk, Z | 1 |
Warmolts, JR | 1 |
Jackson, CE | 1 |
Barohn, RJ | 1 |
Mendell, JR | 1 |
Verma, A | 1 |
Berger, JR | 1 |
Snodgrass, S | 1 |
Petito, C | 1 |
Khan, AR | 1 |
Bertorini, TE | 1 |
Horner, LH | 1 |
Attout, H | 1 |
Rahmeh, F | 1 |
Ziegler, F | 1 |
Feldman, EL | 1 |
Bromberg, MB | 1 |
Albers, JW | 1 |
Pestronk, A | 1 |
1 trial available for prednisone and Motor Neuron Disease
Article | Year |
---|---|
Immunosuppressive treatment of motor neuron syndromes. Attempts to distinguish a treatable disorder.
Topics: Adult; Aged; Amyotrophic Lateral Sclerosis; Cyclophosphamide; Female; G(M1) Ganglioside; Humans; Imm | 1994 |
6 other studies available for prednisone and Motor Neuron Disease
Article | Year |
---|---|
Motor variant of chronic inflammatory demyelinating polyneuropathy in a child.
Topics: Anti-Inflammatory Agents; Biopsy; Child, Preschool; Electrodiagnosis; Electroencephalography; Electr | 2008 |
Different mechanisms may operate in therapies for AIDP and multifocal motor neuropathy.
Topics: Cyclophosphamide; Humans; Immunoglobulins, Intravenous; Motor Neuron Disease; Plasmapheresis; Polyra | 1994 |
Motor neuron disease: a paraneoplastic process associated with anti-hu antibody and small-cell lung carcinoma.
Topics: Anti-Inflammatory Agents; Antibodies, Anti-Idiotypic; Carcinoma, Small Cell; Cerebellum; Fatal Outco | 1996 |
Tongue involvement in a patient with granulomatous myositis.
Topics: Anti-Inflammatory Agents; Deglutition Disorders; Female; Follow-Up Studies; Granuloma; Humans; Middl | 1997 |
[de Gorgerot-Sjogren syndrome simulating amyotrophic lateral sclerosis].
Topics: Aged; Cyclophosphamide; Diagnosis, Differential; Electromyography; Humans; Male; Motor Neuron Diseas | 2000 |
Immunosuppressive treatment in multifocal motor neuropathy.
Topics: Adult; Aged; Antibodies, Anti-Idiotypic; Cyclophosphamide; Female; Humans; Immunoglobulin M; Immunos | 1991 |