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prednisone and Motor Neuron Disease

prednisone has been researched along with Motor Neuron Disease in 7 studies

Prednisone: A synthetic anti-inflammatory glucocorticoid derived from CORTISONE. It is biologically inert and converted to PREDNISOLONE in the liver.
prednisone : A synthetic glucocorticoid drug that is particularly effective as an immunosuppressant, and affects virtually all of the immune system. Prednisone is a prodrug that is converted by the liver into prednisolone (a beta-hydroxy group instead of the oxo group at position 11), which is the active drug and also a steroid.

Motor Neuron Disease: Diseases characterized by a selective degeneration of the motor neurons of the spinal cord, brainstem, or motor cortex. Clinical subtypes are distinguished by the major site of degeneration. In AMYOTROPHIC LATERAL SCLEROSIS there is involvement of upper, lower, and brainstem motor neurons. In progressive muscular atrophy and related syndromes (see MUSCULAR ATROPHY, SPINAL) the motor neurons in the spinal cord are primarily affected. With progressive bulbar palsy (BULBAR PALSY, PROGRESSIVE), the initial degeneration occurs in the brainstem. In primary lateral sclerosis, the cortical neurons are affected in isolation. (Adams et al., Principles of Neurology, 6th ed, p1089)

Research Excerpts

ExcerptRelevanceReference
"Patients with amyotrophic lateral sclerosis failed to improve irrespective of laboratory findings."2.67Immunosuppressive treatment of motor neuron syndromes. Attempts to distinguish a treatable disorder. ( Amato, AA; Barohn, RJ; Jackson, CE; Kissel, JT; Lynn, DJ; Mendell, JR; Rammohan, KW; Sahenk, Z; Tan, E; Warmolts, JR, 1994)
"Although isolated lower motor neuron disease has been reported as a paraneoplastic complication, it has not been previously described, in association with anti-Hu antibody."1.29Motor neuron disease: a paraneoplastic process associated with anti-hu antibody and small-cell lung carcinoma. ( Berger, JR; Petito, C; Snodgrass, S; Verma, A, 1996)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's5 (71.43)18.2507
2000's2 (28.57)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Sinno, DD1
Darras, BT1
Yamout, BI1
Rebeiz, JG1
Mikati, MA1
Tanaka, M1
Tan, E1
Lynn, DJ1
Amato, AA1
Kissel, JT1
Rammohan, KW1
Sahenk, Z1
Warmolts, JR1
Jackson, CE1
Barohn, RJ1
Mendell, JR1
Verma, A1
Berger, JR1
Snodgrass, S1
Petito, C1
Khan, AR1
Bertorini, TE1
Horner, LH1
Attout, H1
Rahmeh, F1
Ziegler, F1
Feldman, EL1
Bromberg, MB1
Albers, JW1
Pestronk, A1

Trials

1 trial available for prednisone and Motor Neuron Disease

ArticleYear
Immunosuppressive treatment of motor neuron syndromes. Attempts to distinguish a treatable disorder.
    Archives of neurology, 1994, Volume: 51, Issue:2

    Topics: Adult; Aged; Amyotrophic Lateral Sclerosis; Cyclophosphamide; Female; G(M1) Ganglioside; Humans; Imm

1994

Other Studies

6 other studies available for prednisone and Motor Neuron Disease

ArticleYear
Motor variant of chronic inflammatory demyelinating polyneuropathy in a child.
    Pediatric neurology, 2008, Volume: 38, Issue:6

    Topics: Anti-Inflammatory Agents; Biopsy; Child, Preschool; Electrodiagnosis; Electroencephalography; Electr

2008
Different mechanisms may operate in therapies for AIDP and multifocal motor neuropathy.
    Muscle & nerve, 1994, Volume: 17, Issue:10

    Topics: Cyclophosphamide; Humans; Immunoglobulins, Intravenous; Motor Neuron Disease; Plasmapheresis; Polyra

1994
Motor neuron disease: a paraneoplastic process associated with anti-hu antibody and small-cell lung carcinoma.
    Annals of neurology, 1996, Volume: 40, Issue:1

    Topics: Anti-Inflammatory Agents; Antibodies, Anti-Idiotypic; Carcinoma, Small Cell; Cerebellum; Fatal Outco

1996
Tongue involvement in a patient with granulomatous myositis.
    Southern medical journal, 1997, Volume: 90, Issue:9

    Topics: Anti-Inflammatory Agents; Deglutition Disorders; Female; Follow-Up Studies; Granuloma; Humans; Middl

1997
[de Gorgerot-Sjogren syndrome simulating amyotrophic lateral sclerosis].
    La Revue de medecine interne, 2000, Volume: 21, Issue:8

    Topics: Aged; Cyclophosphamide; Diagnosis, Differential; Electromyography; Humans; Male; Motor Neuron Diseas

2000
Immunosuppressive treatment in multifocal motor neuropathy.
    Annals of neurology, 1991, Volume: 30, Issue:3

    Topics: Adult; Aged; Antibodies, Anti-Idiotypic; Cyclophosphamide; Female; Humans; Immunoglobulin M; Immunos

1991