prednisone has been researched along with Mevalonate Kinase Deficiency in 4 studies
Prednisone: A synthetic anti-inflammatory glucocorticoid derived from CORTISONE. It is biologically inert and converted to PREDNISOLONE in the liver.
prednisone : A synthetic glucocorticoid drug that is particularly effective as an immunosuppressant, and affects virtually all of the immune system. Prednisone is a prodrug that is converted by the liver into prednisolone (a beta-hydroxy group instead of the oxo group at position 11), which is the active drug and also a steroid.
Mevalonate Kinase Deficiency: Autosomal recessive disorder caused by mutations in the mevalonate kinase gene. Because of the mutations cholesterol biosynthesis is disrupted and MEVALONIC ACID accumulates. It is characterized by a range of symptoms, including dysmorphic FACIES, psychomotor retardation, CATARACT, hepatosplenomegaly, CEREBELLAR ATAXIA, elevated IMMUNOGLOBULIN D, and recurrent febrile crises with FEVER; LYMPHADENOPATHY; ARTHRALGIA; EDEMA; and rash.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Periodic fevers are acquired or inherited disorders of innate immunity, which were first described in the 1940s." | 2.49 | A taste of periodic fever syndromes. ( Chiang, VW; Hazen, MM; Koyfman, A; Lovallo, E, 2013) |
| "We report on two brothers with hyperimmunoglobulinemia D (patient 1: serum immunoglobulin D [IgD] concentration initially 61 IU/ml, later on 340 IU/ml; patient 2: serum IgD concentration 144 IU/ml; normal <100 IU/ml, 97th centile) and periodic fever syndrome (HIDS)." | 1.35 | B cell cytopenia in two brothers with hyper-IgD and periodic fever syndrome. ( Ganschow, R; Sornsakrin, M; Wenner, K, 2009) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 3 (75.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Koyfman, A | 1 |
| Lovallo, E | 1 |
| Hazen, MM | 1 |
| Chiang, VW | 1 |
| Bjornstad, EC | 1 |
| James, K | 1 |
| Culton, D | 1 |
| Williams, C | 1 |
| Wardrop, RM | 1 |
| Sornsakrin, M | 1 |
| Wenner, K | 1 |
| Ganschow, R | 1 |
| Wurster, VM | 1 |
| Carlucci, JG | 1 |
| Edwards, KM | 1 |
2 reviews available for prednisone and Mevalonate Kinase Deficiency
| Article | Year |
|---|---|
A taste of periodic fever syndromes.
Topics: Amyloidosis; Anti-Inflammatory Agents, Non-Steroidal; Carrier Proteins; Colchicine; Cold Temperature | 2013 |
Periodic Fever syndromes.
Topics: Anti-Bacterial Agents; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Antibodies | 2011 |
2 other studies available for prednisone and Mevalonate Kinase Deficiency
| Article | Year |
|---|---|
Erythema Nodosum and Fevers.
Topics: Adolescent; Diagnosis, Differential; Erythema Nodosum; Fever; Glucocorticoids; Humans; Male; Mevalon | 2015 |
B cell cytopenia in two brothers with hyper-IgD and periodic fever syndrome.
Topics: Agammaglobulinemia; Azathioprine; B-Lymphocytes; Child; Fever; Glucocorticoids; Heterozygote; Humans | 2009 |