prednisone has been researched along with Metabolic Syndrome in 7 studies
Prednisone: A synthetic anti-inflammatory glucocorticoid derived from CORTISONE. It is biologically inert and converted to PREDNISOLONE in the liver.
prednisone : A synthetic glucocorticoid drug that is particularly effective as an immunosuppressant, and affects virtually all of the immune system. Prednisone is a prodrug that is converted by the liver into prednisolone (a beta-hydroxy group instead of the oxo group at position 11), which is the active drug and also a steroid.
Metabolic Syndrome: A cluster of symptoms that are risk factors for CARDIOVASCULAR DISEASES and TYPE 2 DIABETES MELLITUS. The major components of metabolic syndrome include ABDOMINAL OBESITY; atherogenic DYSLIPIDEMIA; HYPERTENSION; HYPERGLYCEMIA; INSULIN RESISTANCE; a proinflammatory state; and a prothrombotic (THROMBOSIS) state.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To determine the relationship between current hydroxychloroquine (HCQ) use and 2 indicators of glycemic control, fasting glucose and insulin sensitivity, in nondiabetic women with systemic lupus erythematosus (SLE) or rheumatoid arthritis (RA)." | 7.76 | Hydroxychloroquine and glycemia in women with rheumatoid arthritis and systemic lupus erythematosus. ( Elliott, JR; Kao, AH; Kuller, L; Manzi, S; Penn, SK; Schott, LL; Toledo, FG; Wasko, MC, 2010) |
| "To determine the relationship between current hydroxychloroquine (HCQ) use and 2 indicators of glycemic control, fasting glucose and insulin sensitivity, in nondiabetic women with systemic lupus erythematosus (SLE) or rheumatoid arthritis (RA)." | 3.76 | Hydroxychloroquine and glycemia in women with rheumatoid arthritis and systemic lupus erythematosus. ( Elliott, JR; Kao, AH; Kuller, L; Manzi, S; Penn, SK; Schott, LL; Toledo, FG; Wasko, MC, 2010) |
| " The ability of emodin to inhibit prednisone- or dexamethasone-induced insulin resistance was investigated in C57BL/6J mice and its effect on metabolic abnormalities was observed in DIO mice." | 3.76 | Emodin, a natural product, selectively inhibits 11beta-hydroxysteroid dehydrogenase type 1 and ameliorates metabolic disorder in diet-induced obese mice. ( Chen, JH; Dou, W; Feng, Y; Huang, SL; Leng, Y; Shen, JH; Shen, Y; Zhang, S, 2010) |
| "Chloroquine has a protective effect on the prevalence of metabolic syndrome in these patients, and this benefit counteracts the deleterious effect of glucocorticoids in a dose-dependent manner." | 1.42 | Impact of Therapy on Metabolic Syndrome in Young Adult Premenopausal Female Lupus Patients: Beneficial Effect of Antimalarials. ( Bonfá, E; Borba, EF; Muniz, LF; Pereira, RMR; Silva, TF, 2015) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 6 (85.71) | 24.3611 |
| 2020's | 1 (14.29) | 2.80 |
| Authors | Studies |
|---|---|
| Soliman, AT | 1 |
| Hamed, N | 1 |
| De Sanctis, V | 1 |
| Elbaba, M | 1 |
| Alyafei, F | 1 |
| Alaaraj, N | 1 |
| Ahmad, S | 1 |
| Itani, M | 1 |
| Al-Naimi, F | 1 |
| Khater, D | 1 |
| de Steenwinkel, FDO | 1 |
| Dolhain, RJEM | 1 |
| Hazes, JMW | 1 |
| Hokken-Koelega, ACS | 1 |
| Monção, CSA | 1 |
| Martins, LN | 1 |
| Penteado, MPS | 1 |
| Reis, RCP | 1 |
| Santos, FMM | 1 |
| Lanna, CCD | 1 |
| Ribeiro, AL | 1 |
| Telles, RW | 1 |
| Muniz, LF | 1 |
| Pereira, RMR | 1 |
| Silva, TF | 1 |
| Bonfá, E | 1 |
| Borba, EF | 1 |
| Penn, SK | 1 |
| Kao, AH | 1 |
| Schott, LL | 1 |
| Elliott, JR | 1 |
| Toledo, FG | 1 |
| Kuller, L | 1 |
| Manzi, S | 1 |
| Wasko, MC | 1 |
| Feng, Y | 1 |
| Huang, SL | 1 |
| Dou, W | 1 |
| Zhang, S | 1 |
| Chen, JH | 1 |
| Shen, Y | 1 |
| Shen, JH | 1 |
| Leng, Y | 1 |
| Perera, M | 1 |
| Suarez, A | 1 |
| Luzardo, H | 1 |
| Lopez, J | 1 |
| Molero, T | 1 |
7 other studies available for prednisone and Metabolic Syndrome
| Article | Year |
|---|---|
The long-term (five years) effects of prednisone therapy in children with frequently relapsing nephrotic syndrome: A controlled study of anthropometric parameters and metabolic abnormalities.
Topics: Child; Cholesterol; Glucose; Humans; Metabolic Syndrome; Nephrotic Syndrome; Obesity; Prednisolone; | 2022 |
Does prednisone use or disease activity in pregnant women with rheumatoid arthritis influence the body composition of their offspring?
Topics: Adult; Arthritis, Rheumatoid; Body Composition; Child; Female; Glucocorticoids; Humans; Infant, Newb | 2017 |
Incidence of cardiovascular risk factors in female patients with systemic lupus erythematosus: a 3-year follow-up cohort.
Topics: Adult; Age Factors; Brazil; Dyslipidemias; Female; Follow-Up Studies; Humans; Hypertension; Incidenc | 2018 |
Impact of Therapy on Metabolic Syndrome in Young Adult Premenopausal Female Lupus Patients: Beneficial Effect of Antimalarials.
Topics: Adult; Antimalarials; Brazil; Chloroquine; Cross-Sectional Studies; Female; Glucocorticoids; Humans; | 2015 |
Hydroxychloroquine and glycemia in women with rheumatoid arthritis and systemic lupus erythematosus.
Topics: Antirheumatic Agents; Arthritis, Rheumatoid; Blood Glucose; Cross-Sectional Studies; Diabetes Mellit | 2010 |
Emodin, a natural product, selectively inhibits 11beta-hydroxysteroid dehydrogenase type 1 and ameliorates metabolic disorder in diet-induced obese mice.
Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 1; Adrenal Cortex Hormones; Animals; Cell Line; Dexamethas | 2010 |
Spontaneous remission after a year of romiplostim in an adult patient with refractory primary immune thrombocytopenia.
Topics: Antibodies, Monoclonal, Murine-Derived; Anticoagulants; Aspirin; Clopidogrel; Drug Resistance; Hemor | 2012 |