prednisone has been researched along with Mandibular Diseases in 12 studies
Prednisone: A synthetic anti-inflammatory glucocorticoid derived from CORTISONE. It is biologically inert and converted to PREDNISOLONE in the liver.
prednisone : A synthetic glucocorticoid drug that is particularly effective as an immunosuppressant, and affects virtually all of the immune system. Prednisone is a prodrug that is converted by the liver into prednisolone (a beta-hydroxy group instead of the oxo group at position 11), which is the active drug and also a steroid.
Mandibular Diseases: Diseases involving the MANDIBLE.
| Excerpt | Relevance | Reference |
|---|---|---|
| " We report a case of BRONJ in a patient following six years of oral BP administration for the management of osteoporosis, complicated by four years of prednisone therapy for pulmonary fibrosis." | 3.81 | Risk Factors in the Development of Oral Bisphosphonate-induced Osteonecrosis. ( Reiss, S; Sultan, D, 2015) |
| "We have described a 60-year-old woman with polymyalgia rheumatica treated initially with prednisone but ultimately with azathioprine and cyclophosphamide." | 3.67 | Trigeminal herpes zoster causing mandibular osteonecrosis and spontaneous tooth exfoliation. ( Canter, HG; Manz, HJ; Melton, J, 1986) |
| "Diabetes insipidus is considered to be an important indicator of serious underlying diseases in children, including LCH." | 1.38 | Monostotic Langerhans' cell histiocytosis in a child with central diabetes insipidus. ( Alves, AP; Costa, FW; Fonteles, CS; Gurgel, MH; Quidute, AR; Soares, EC, 2012) |
| "In conclusion, profound marginal periodontal bone loss does not seem to be a prominent side-effect of long-term glucocorticosteroid treatment, although the degree of induced osteopenia in the mandible corresponds to that in other cortical bones of the skeleton." | 1.28 | Steroid-induced mandibular bone loss in relation to marginal periodontal changes. ( Klausen, B; Olgaard, K; von Wowern, N, 1992) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (25.00) | 18.7374 |
| 1990's | 3 (25.00) | 18.2507 |
| 2000's | 1 (8.33) | 29.6817 |
| 2010's | 4 (33.33) | 24.3611 |
| 2020's | 1 (8.33) | 2.80 |
| Authors | Studies |
|---|---|
| Qadadha, YM | 1 |
| Gauthier, GM | 1 |
| Hartig, GK | 1 |
| Reiss, S | 1 |
| Sultan, D | 1 |
| Delanian, S | 1 |
| Chatel, C | 1 |
| Porcher, R | 1 |
| Depondt, J | 1 |
| Lefaix, JL | 1 |
| Adams, B | 1 |
| Lazarchick, J | 1 |
| Medina, AM | 1 |
| Willner, IR | 1 |
| Neville, B | 1 |
| Murphy, E | 1 |
| Stuart, R | 1 |
| Costa, LJ | 1 |
| Soares, EC | 1 |
| Quidute, AR | 1 |
| Costa, FW | 1 |
| Gurgel, MH | 1 |
| Alves, AP | 1 |
| Fonteles, CS | 1 |
| Chun, CS | 1 |
| Cowan, J | 1 |
| Moenning, JE | 1 |
| Bussard, DA | 1 |
| Keppler, A | 1 |
| Boom, J | 1 |
| von Wowern, N | 1 |
| Klausen, B | 1 |
| Olgaard, K | 1 |
| Dubaniewicz, A | 1 |
| Kuziemski, W | 1 |
| Wybieralska, M | 1 |
| Manz, HJ | 1 |
| Canter, HG | 1 |
| Melton, J | 1 |
| Mason, DA | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Pentoxifylline and Tocopherol (PENTO) in the Treatment of Medication-related Osteonecrosis of the Jaw (MRONJ): A Prospective, Randomized Controlled Trial to Evaluate a Novel Non-operative Treatment[NCT03040778] | Phase 3 | 100 participants (Anticipated) | Interventional | 2018-04-01 | Enrolling by invitation | ||
| Advances in the Management of Mandibular Osteoradionecrosis: Pentoxifylline and Tocopherol as Medical Treatment[NCT02368457] | Phase 4 | 24 participants (Actual) | Interventional | 2016-02-29 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
"Clinical healing assessment as measured with the classification of ORN stages, area of bone exposed (mm2) and radiological findings (OPG).~Intraoral bone exposure is measured in mm2." (NCT02368457)
Timeframe: From baseline to 1, 3, 6, and 9 months of starting treatment
| Intervention | mm2 (Mean) | |||
|---|---|---|---|---|
| 1 month of starting treatment | 3 month of starting treatment | 6 month of starting treatment | 9 month of starting treatment | |
| Control Group | 15 | 15 | 15 | 15 |
| Pentoxifylline and Tocopherol | 14 | 13 | 11.5 | 10 |
"Evaluation of symptoms improvement using the LENT-SOMA scale (Late Effect Normal Tissue Task Force / Subjective, Objective, Management, Analytic scale).~To examine the LENT/SOMA scale prospectively using interviews and questionnaires~Assessments were made from baseline to 1, 3, 6 and 9 months of starting treatments. The acceptability and feasibility of using the scales was examined using compliance in completion of the questionnaires.~Maximum score: 36 Minimum score: 0~Questionnaires have been completed for 24 patients after treatment. Higher values represents worse outcome.~Scale categories:~Subjective: pain, nutritional problems, difficulty in mouth openning. Objective: bone exposure, trismus, Management: analgesic treatment, oral treatment, nutrition. Analytic: radiological findings." (NCT02368457)
Timeframe: From baseline to 1,3, 6, 9 months of starting treatment
| Intervention | units on a scale (Mean) | |||
|---|---|---|---|---|
| 1 month of starting treatment | 3 month of starting treatment | 6 month of starting treatment | 9 month of starting treatment | |
| CONTROL | 15.5 | 15.5 | 15.5 | 15.5 |
| Pentoxifylline and Tocopherol | 14.5 | 14 | 14 | 13.3 |
1 review available for prednisone and Mandibular Diseases
| Article | Year |
|---|---|
Chronic recurrent multifocal osteomyelitis of the spine and mandible: case report and review of the literature.
Topics: Alendronate; Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Child, Preschool; Chron | 2004 |
1 trial available for prednisone and Mandibular Diseases
| Article | Year |
|---|---|
Complete restoration of refractory mandibular osteoradionecrosis by prolonged treatment with a pentoxifylline-tocopherol-clodronate combination (PENTOCLO): a phase II trial.
Topics: Adult; Aged; Aged, 80 and over; Bone Density Conservation Agents; Ciprofloxacin; Clodronic Acid; Dru | 2011 |
Complete restoration of refractory mandibular osteoradionecrosis by prolonged treatment with a pentoxifylline-tocopherol-clodronate combination (PENTOCLO): a phase II trial.
Topics: Adult; Aged; Aged, 80 and over; Bone Density Conservation Agents; Ciprofloxacin; Clodronic Acid; Dru | 2011 |
Complete restoration of refractory mandibular osteoradionecrosis by prolonged treatment with a pentoxifylline-tocopherol-clodronate combination (PENTOCLO): a phase II trial.
Topics: Adult; Aged; Aged, 80 and over; Bone Density Conservation Agents; Ciprofloxacin; Clodronic Acid; Dru | 2011 |
Complete restoration of refractory mandibular osteoradionecrosis by prolonged treatment with a pentoxifylline-tocopherol-clodronate combination (PENTOCLO): a phase II trial.
Topics: Adult; Aged; Aged, 80 and over; Bone Density Conservation Agents; Ciprofloxacin; Clodronic Acid; Dru | 2011 |
10 other studies available for prednisone and Mandibular Diseases
| Article | Year |
|---|---|
Progressive Inflammatory Process of the Mandible and Surrounding Soft Tissues.
Topics: Dental Prosthesis, Implant-Supported; Diagnosis, Differential; Face; Glucocorticoids; Humans; Inflam | 2022 |
Risk Factors in the Development of Oral Bisphosphonate-induced Osteonecrosis.
Topics: Abscess; Administration, Oral; Aged, 80 and over; Bisphosphonate-Associated Osteonecrosis of the Jaw | 2015 |
Iatrogenic immunodeficiency-associated lymphoproliferative disease of the Hodgkin lymphoma-like variant in a patient treated with mycophenolate mofetil for autoimmune hepatitis.
Topics: Adult; Antibodies, Monoclonal; Antibodies, Monoclonal, Murine-Derived; Azathioprine; Diagnosis, Diff | 2010 |
Monostotic Langerhans' cell histiocytosis in a child with central diabetes insipidus.
Topics: Anti-Inflammatory Agents; Antidiuretic Agents; Child, Preschool; Cytostatic Agents; Deamino Arginine | 2012 |
Glucocorticoid therapy for myasthenia gravis resulting in resorption of the mandibular condyles.
Topics: Adult; Bone Resorption; Female; Humans; Mandibular Condyle; Mandibular Diseases; Myasthenia Gravis; | 1995 |
[What is your diagnosis].
Topics: Animals; Bone Diseases; Dog Diseases; Dogs; Male; Mandibular Diseases; Prednisone; Skull | 1975 |
Steroid-induced mandibular bone loss in relation to marginal periodontal changes.
Topics: Adult; Alveolar Bone Loss; Anti-Inflammatory Agents; Bone Density; Bone Resorption; Dental Plaque; F | 1992 |
[Interstitial lung disease in Langerhans-cell granulomatosis in a 34-year-old woman].
Topics: Adult; Diabetes Insipidus; Eosinophilic Granuloma; Female; Humans; Mandibular Diseases; Osteolysis; | 1991 |
Trigeminal herpes zoster causing mandibular osteonecrosis and spontaneous tooth exfoliation.
Topics: Azathioprine; Cranial Nerve Diseases; Cyclophosphamide; Drug Therapy, Combination; Female; Herpes Zo | 1986 |
Steroid therapy and dental infection. Case report.
Topics: Adult; Cellulitis; Dry Socket; Female; Humans; Mandibular Diseases; Prednisone; Tooth Extraction | 1970 |