Page last updated: 2024-11-07

prednisone and Malnutrition

prednisone has been researched along with Malnutrition in 6 studies

Prednisone: A synthetic anti-inflammatory glucocorticoid derived from CORTISONE. It is biologically inert and converted to PREDNISOLONE in the liver.
prednisone : A synthetic glucocorticoid drug that is particularly effective as an immunosuppressant, and affects virtually all of the immune system. Prednisone is a prodrug that is converted by the liver into prednisolone (a beta-hydroxy group instead of the oxo group at position 11), which is the active drug and also a steroid.

Malnutrition: An imbalanced nutritional status resulting from insufficient intake of nutrients to meet normal physiological requirement.

Research Excerpts

ExcerptRelevanceReference
", we analyzed 262 patients who had been treated with Ruximab-cyclophosphamide, doxorubicin, vincristine, and prednisone for newly diagnosed diffuse large B-cell lymphoma (DLBCL) and for whom data were available regarding pretreatment nutritional status."3.80Effect of nutritional status on survival outcome of diffuse large B-cell lymphoma patients treated with rituximab-CHOP. ( Cho, JW; Han, B; Kim, S; Kim, SJ; Kim, WS; Park, S; Woo, SY, 2014)
" The pharmacokinetic comparability of Prolastin-C to Prolastin was assessed in subjects with AAT deficiency."2.75Pharmacokinetic comparability of Prolastin®-C to Prolastin® in alpha₁-antitrypsin deficiency: a randomized study. ( Brantly, ML; Campos, MA; Chapman, KR; Kueppers, F; Sandhaus, RA; Stocks, JM; Strange, C; Turino, G; Wang-Smith, L, 2010)
"Survival for childhood acute lymphoblastic leukemia (ALL) has improved significantly, but these benefits may not be available to many children from low and middle income countries, where reasons for treatment failure may be unique to their environment."1.43The Impact of Socioeconomic Factors on the Outcome of Childhood Acute Lymphoblastic Leukemia (ALL) Treatment in a Low/Middle Income Country (LMIC). ( Ashraf, MS; Belgaumi, AF; Iftikhar, S; Jabeen, K, 2016)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's5 (83.33)24.3611
2020's1 (16.67)2.80

Authors

AuthorsStudies
Serrano, OK1
Kutzler, HL1
Rochon, C1
Radojevic, JA1
Lawlor, MT1
Hammond, JA1
Gluck, J1
Feingold, AD1
Jaiswal, A1
Kanemasa, Y1
Shimoyama, T1
Sasaki, Y1
Hishima, T1
Omuro, Y1
Cockey, G1
Shah, SR1
Hampton, T1
Park, S1
Han, B1
Cho, JW1
Woo, SY1
Kim, S1
Kim, SJ1
Kim, WS1
Jabeen, K1
Ashraf, MS1
Iftikhar, S1
Belgaumi, AF1
Stocks, JM1
Brantly, ML1
Wang-Smith, L1
Campos, MA1
Chapman, KR1
Kueppers, F1
Sandhaus, RA1
Strange, C1
Turino, G1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Multi-center, Randomized, Double-blind, Crossover Trial to Evaluate the Pharmacokinetic Comparability of Alpha-1 MP to Prolastin in Subjects With Alpha1-antitrypsin Deficiency.[NCT00295061]Phase 324 participants (Actual)Interventional2006-05-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Alpha-1 MP vs. Prolastin® of Area Under the Curve (AUC) From Day 0 to Day 7

"The primary objective of this study was to demonstrate the pharmacokinetic comparability (geometric least square mean ratio of AUC between the Alpha-1 MP vs. Prolastin®, 90% confidence interval falls within 0.80-1.25, FDA Guidance as being bioequivalent between two treatments) of Alpha-1 MP to Prolastin® in subjects with alpha-1-anti-trypsin (AAT) deficiency by comparing AUC from Day 0 to Day 7 of plasma Alpha1-PI measured by the functional activity (potency) assay. AUC from Day 0 to Day 7 was calculated at steady state at the end of the first and second 8-week treatment periods during the 16-week double-blind, crossover phase." (NCT00295061)
Timeframe: Day 0 to Day 7

Interventionmg*h/mL (Number)
Alpha-1 MP155.9
Prolastin152.4

Trials

1 trial available for prednisone and Malnutrition

ArticleYear
Pharmacokinetic comparability of Prolastin®-C to Prolastin® in alpha₁-antitrypsin deficiency: a randomized study.
    BMC clinical pharmacology, 2010, Sep-30, Volume: 10

    Topics: alpha 1-Antitrypsin; alpha 1-Antitrypsin Deficiency; Antineoplastic Combined Chemotherapy Protocols;

2010

Other Studies

5 other studies available for prednisone and Malnutrition

ArticleYear
Incidental COVID-19 in a heart-kidney transplant recipient with malnutrition and recurrent infections: Implications for the SARS-CoV-2 immune response.
    Transplant infectious disease : an official journal of the Transplantation Society, 2020, Volume: 22, Issue:6

    Topics: Antibiotics, Antineoplastic; Bacteremia; BK Virus; Cardiomyopathy, Dilated; Cardiotoxicity; COVID-19

2020
Geriatric nutritional risk index as a prognostic factor in patients with diffuse large B cell lymphoma.
    Annals of hematology, 2018, Volume: 97, Issue:6

    Topics: Adult; Age Factors; Aged; Aged, 80 and over; Antibodies, Monoclonal, Murine-Derived; Antineoplastic

2018
Giant Cell Arteritis Presenting with a Tongue Lesion.
    The American journal of medicine, 2019, Volume: 132, Issue:5

    Topics: Aged, 80 and over; Biopsy; Deglutition Disorders; Diagnosis, Differential; Female; Gastrostomy; Gian

2019
Effect of nutritional status on survival outcome of diffuse large B-cell lymphoma patients treated with rituximab-CHOP.
    Nutrition and cancer, 2014, Volume: 66, Issue:2

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anthropometry; Antibodies, Monoclonal, Murine-Derived; A

2014
The Impact of Socioeconomic Factors on the Outcome of Childhood Acute Lymphoblastic Leukemia (ALL) Treatment in a Low/Middle Income Country (LMIC).
    Journal of pediatric hematology/oncology, 2016, Volume: 38, Issue:8

    Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Child; Child, Preschool; D

2016