Page last updated: 2024-11-07

prednisone and Lipodystrophy

prednisone has been researched along with Lipodystrophy in 18 studies

Prednisone: A synthetic anti-inflammatory glucocorticoid derived from CORTISONE. It is biologically inert and converted to PREDNISOLONE in the liver.
prednisone : A synthetic glucocorticoid drug that is particularly effective as an immunosuppressant, and affects virtually all of the immune system. Prednisone is a prodrug that is converted by the liver into prednisolone (a beta-hydroxy group instead of the oxo group at position 11), which is the active drug and also a steroid.

Lipodystrophy: A collection of heterogenous conditions resulting from defective LIPID METABOLISM and characterized by ADIPOSE TISSUE atrophy. Often there is redistribution of body fat resulting in peripheral fat wasting and central adiposity. They include generalized, localized, congenital, and acquired lipodystrophy.

Research Excerpts

ExcerptRelevanceReference
"Lipodystrophy and neuropsychiatric disorders are common adverse events of long-term prednisone therapy and are particularly distressing for the patients concerned."3.74Corticosteroid-induced clinical adverse events: frequency, risk factors and patient's opinion. ( Cabane, J; Fardet, L; Flahault, A; Généreau, T; Kettaneh, A; Lebbé, C; Tiev, KP; Tolédano, C, 2007)
"Acromegaly is characterized by growth hormone (GH) and insulinlike growth factor-1 (IGF-1) hypersecretion, and GH and IGF-1 play important roles in regulating body composition and glucose homeostasis."1.46Body Composition and Ectopic Lipid Changes With Biochemical Control of Acromegaly. ( Bredella, MA; Dichtel, LE; Gerweck, AV; Miller, KK; Schorr, M; Swearingen, B; Woodmansee, WW; Young, BJ, 2017)
"Lipoatrophic panniculitis (LP) is a rare disease of childhood characterized by eruption of tender erythematous nodules and plaques followed by circumferential bands of lipoatrophy often seen on the arms and legs."1.36Lipoatrophic panniculitis: case report and review of the literature. ( Edmonson, MB; Gottam, CC; Hinshaw, MA; Shen, LY; Teng, JM; Williams, GP, 2010)
"All consecutive patients starting long-term, high dosage corticosteroid therapy were photographed at baseline and after 3 months of therapy."1.35Digital photography as an operational tool for assessing corticosteroid-induced lipodystrophy. ( Cabane, J; Fabre, B; Fardet, L; Flahault, A; Kettaneh, A; Tiev, KP; Tolédano, C, 2008)
"Erythema nodosum was suspected and some transient improvement was obtained with intravenous antibiotics and glucocorticoids."1.33[Panniculitis in a 32-year-old man]. ( Hrycaj, P, 2006)
"A 10-year-old boy had juvenile dermatomyositis and multiple asymmetric lesions of lipoatrophy."1.28Dermatomyositis associated with multifocal lipoatrophy. ( Commens, C; O'Neill, P; Walker, G, 1990)

Research

Studies (18)

TimeframeStudies, this research(%)All Research%
pre-19908 (44.44)18.7374
1990's2 (11.11)18.2507
2000's5 (27.78)29.6817
2010's3 (16.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bredella, MA1
Schorr, M1
Dichtel, LE1
Gerweck, AV1
Young, BJ1
Woodmansee, WW1
Swearingen, B1
Miller, KK1
Chantelau, EA1
Prätor, R1
Prätor, J1
Fardet, L2
Kettaneh, A2
Tiev, KP2
Fabre, B1
Tolédano, C2
Cabane, J2
Flahault, A2
Shen, LY1
Edmonson, MB1
Williams, GP1
Gottam, CC1
Hinshaw, MA1
Teng, JM1
HUNTER, RC1
WARD, JR1
WEINER, RG1
GRADINGER, BC1
RATE, RG1
PEREZ, V1
SCHAPIRA, A1
DE PELLEGRINO, AI1
RYBAK, BJ1
DE LARRECHEA, I1
KELLY, JJ1
WEISIGER, BB1
TRIER, JS1
PHELPS, PC1
EIDELMAN, S1
RUBIN, CE1
Bird, BR1
Daly, PA1
Hrycaj, P1
Généreau, T1
Lebbé, C1
Lee, LA1
Hobbs, KF1
Font, J1
Herrero, C1
Bosch, X1
Cervera, R1
Ingelmo, M1
Mascaró, JM1
Commens, C1
O'Neill, P1
Walker, G1
West, CD1
Oppermann, J1
Wojtarowicz, E1
Mazurek, A1
Woźniak, S1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Steroid-induced Mood Changes in Patients With Inflammatory Bowel Disease[NCT01981889]Phase 453 participants (Actual)Interventional2013-10-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Other Studies

18 other studies available for prednisone and Lipodystrophy

ArticleYear
Body Composition and Ectopic Lipid Changes With Biochemical Control of Acromegaly.
    The Journal of clinical endocrinology and metabolism, 2017, 11-01, Volume: 102, Issue:11

    Topics: Acromegaly; Adipose Tissue; Adult; Aged; Blood Glucose; Body Composition; Cabergoline; Case-Control

2017
Insulin-induced localized lipoatrophy preceded by shingles (herpes zoster): a case report.
    Journal of medical case reports, 2014, Jun-24, Volume: 8

    Topics: Atrophy; Diabetes Mellitus, Type 1; Female; Glucocorticoids; Herpes Zoster; Humans; Hypoglycemic Age

2014
Digital photography as an operational tool for assessing corticosteroid-induced lipodystrophy.
    European journal of internal medicine, 2008, Volume: 19, Issue:5

    Topics: Clinical Competence; Female; Glucocorticoids; Humans; Lipodystrophy; Male; Middle Aged; Observer Var

2008
Lipoatrophic panniculitis: case report and review of the literature.
    Archives of dermatology, 2010, Volume: 146, Issue:8

    Topics: Ankle; Anti-Inflammatory Agents; Antirheumatic Agents; Biopsy; Child; Drug Therapy, Combination; Hum

2010
Intestinal lipodystrophy (Whipple's disease) treated with ACTH and corticosteroids.
    The American journal of digestive diseases, 1957, Volume: 2, Issue:7

    Topics: Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Cardiovascular Agents; Cortisone; Glucocortico

1957
Treatment of Whipple's disease with steroids.
    The American journal of gastroenterology, 1961, Volume: 35

    Topics: Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Disease; Intestinal Diseases; Intestine, Small

1961
LIGHT- AND ELECTRON-MICROSCOPE FINDINGS ON JEJUNAL BIOPSY IN WHIPPLE'S DISEASE: STUDIES BEFORE AND AFTER ANTIBIOTIC THERAPY.
    The American journal of digestive diseases, 1963, Volume: 8

    Topics: Adrenocorticotropic Hormone; Anti-Bacterial Agents; Biopsy; Blood Proteins; Blood Transfusion; Chlor

1963
THE ARTHRITIS OF WHIPPLE'S DISEASE.
    Arthritis and rheumatism, 1963, Volume: 6

    Topics: Adrenocorticotropic Hormone; Anti-Bacterial Agents; Antibiotics, Antitubercular; Arthritis; Biopsy;

1963
WHIPPLE'S DISEASE: LIGHT AND ELECTRON MICROSCOPE CORRELATION OF JEJUNAL MUCOSAL HISTOLOGY WITH ANTIBIOTIC TREATMENT AND CLINICAL STATUS.
    Gastroenterology, 1965, Volume: 48

    Topics: Anti-Bacterial Agents; Bacteria; Drug Therapy; Electrons; Geriatrics; Humans; Intestines; Jejunum; L

1965
Uncommon hematologic malignancies. Case 3. Parotid swelling during treatment for transformed mycosis fungoides.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2003, Nov-15, Volume: 21, Issue:22

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cell Transformation, Neoplastic; Cyclopho

2003
[Panniculitis in a 32-year-old man].
    Annales Academiae Medicae Stetinensis, 2006, Volume: 52 Suppl 2

    Topics: Adult; Azathioprine; Diagnosis, Differential; Erythema Nodosum; Humans; Lipodystrophy; Lymphoma, T-C

2006
Corticosteroid-induced clinical adverse events: frequency, risk factors and patient's opinion.
    The British journal of dermatology, 2007, Volume: 157, Issue:1

    Topics: Adrenal Cortex Hormones; Adult; Aged; Anti-Inflammatory Agents; Attitude to Health; Cohort Studies;

2007
Lipodystrophy and metabolic abnormalities in a case of adult dermatomyositis.
    Journal of the American Academy of Dermatology, 2007, Volume: 57, Issue:5 Suppl

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Dermatomyositis; Drug Therapy, Combination; Female; Glucoco

2007
Systemic lupus erythematosus in a patient with partial lipodystrophy.
    Journal of the American Academy of Dermatology, 1990, Volume: 22, Issue:2 Pt 2

    Topics: Adult; Complement C3; Female; Humans; Lipodystrophy; Lupus Erythematosus, Systemic; Prednisone

1990
Dermatomyositis associated with multifocal lipoatrophy.
    Journal of the American Academy of Dermatology, 1990, Volume: 22, Issue:5 Pt 2

    Topics: Buttocks; Child; Dermatomyositis; Humans; Lipodystrophy; Male; Panniculitis; Prednisone

1990
What is the risk of developing glomerulonephritis in a child with facial lipodystrophy and hypocomplementemia?
    Pediatric nephrology (Berlin, Germany), 1989, Volume: 3, Issue:2

    Topics: Biopsy; Child; Child, Preschool; Complement System Proteins; Face; Glomerulonephritis; Humans; Kidne

1989
[Contribution to the pathogenesis and therapy of progressive lipodystrophy].
    Zeitschrift fur Kinderheilkunde, 1965, Oct-01, Volume: 94, Issue:1

    Topics: Cerebral Ventriculography; Child; Diagnosis, Differential; Female; Humans; Kidney; Lipodystrophy; Li

1965
[Effect of hormonal therapy in a case of progressive lipodystrophy].
    Pediatria polska, 1969, Volume: 44, Issue:3

    Topics: Child; Female; Humans; Lipodystrophy; Prednisone

1969