Page last updated: 2024-11-07

prednisone and Leukemic Infiltration

prednisone has been researched along with Leukemic Infiltration in 24 studies

Prednisone: A synthetic anti-inflammatory glucocorticoid derived from CORTISONE. It is biologically inert and converted to PREDNISOLONE in the liver.
prednisone : A synthetic glucocorticoid drug that is particularly effective as an immunosuppressant, and affects virtually all of the immune system. Prednisone is a prodrug that is converted by the liver into prednisolone (a beta-hydroxy group instead of the oxo group at position 11), which is the active drug and also a steroid.

Leukemic Infiltration: A pathologic change in leukemia in which leukemic cells permeate various organs at any stage of the disease. All types of leukemia show various degrees of infiltration, depending upon the type of leukemia. The degree of infiltration may vary from site to site. The liver and spleen are common sites of infiltration, the greatest appearing in myelocytic leukemia, but infiltration is seen also in the granulocytic and lymphocytic types. The kidney is also a common site and of the gastrointestinal system, the stomach and ileum are commonly involved. In lymphocytic leukemia the skin is often infiltrated. The central nervous system too is a common site.

Research Excerpts

ExcerptRelevanceReference
"Treatment of childhood relapsed acute lymphoblastic leukemia (ALL) remains a significant challenge."2.73Reinduction platform for children with first marrow relapse of acute lymphoblastic Leukemia: A Children's Oncology Group Study[corrected]. ( Borowitz, MJ; Camitta, BM; Carroll, WL; Devidas, M; Gaynon, PS; Hunger, SP; Linda, SB; Raetz, EA; Winick, NJ, 2008)
"BACKGROUND Most patients with chronic lymphocytic leukemia (CLL) are asymptomatic at diagnosis, but 10% present with B symptoms."1.56Subcutaneous Masses as an Unusual Manifestation of Relapse in a Case of Atypical Chronic Lymphocytic Leukemia with Prolymphocytoid Transformation and Complex Karyotype: A Diagnostic Dilemma and Treatment Challenge. ( Abdulla, MAJ; Aldapt, MB; Sharaf Eldean, MZ; Shwaylia, HM; Soliman, D; Szabados, L; Yassin, MA, 2020)
"Infants diagnosed with acute lymphoblastic leukemia (ALL) are considered the patient subgroup at the highest risk for central nervous system (CNS) disease, both at presentation and as an isolated extramedullary relapse."1.30Neurodevelopmental outcome of infants with acute lymphoblastic leukemia: a Children's Cancer Group report. ( Kaleita, TA; MacLean, WE; Reaman, GH; Sather, HN; Whitt, JK, 1999)
"Relapsed acute lymphoblastic leukemia (ALL) usually carries a dire prognosis."1.29Effectiveness of intensified rotational combination chemotherapy for late hematologic relapse of childhood acute lymphoblastic leukemia. ( Benaim, E; Crist, WM; Hudson, MM; Liu, Q; Pui, CH; Ribeiro, RC; Rivera, GK, 1996)

Research

Studies (24)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's6 (25.00)18.2507
2000's11 (45.83)29.6817
2010's5 (20.83)24.3611
2020's2 (8.33)2.80

Authors

AuthorsStudies
Mir, TH1
Sharma, A1
Nisar, S1
Khan, AA1
Shah, TA1
Wani, NA1
Aldapt, MB1
Soliman, D1
Szabados, L1
Sharaf Eldean, MZ1
Shwaylia, HM1
Abdulla, MAJ1
Yassin, MA1
Nascimbeni, C1
Chantepie, S1
Brugiere, C1
Comoz, F1
Salaun, V1
Verneuil, L1
Raetz, EA1
Borowitz, MJ1
Devidas, M1
Linda, SB1
Hunger, SP1
Winick, NJ1
Camitta, BM1
Gaynon, PS1
Carroll, WL1
Leeper, NJ1
Dhaliwal, G1
Saint, S1
Witteles, RM1
Jeong, KH1
Lew, BL1
Sim, WY1
Parasole, R1
Petruzziello, F1
Menna, G1
Mangione, A1
Cianciulli, E1
Buffardi, S1
Marchese, L1
Nastro, A1
Misuraca, A1
Poggi, V1
Canova, F1
Marino, D1
Trentin, C1
Soldà, C1
Ghiotto, C1
Aversa, SM1
Ichikawa, S1
Fukuhara, N1
Yamamoto, J1
Suzuki, M1
Nakajima, S1
Okitsu, Y1
Kohata, K1
Onishi, Y1
Ishizawa, K1
Kameoka, J1
Harigae, H1
Aymard, B1
Beghoura, R1
Molina, TJ1
Litwin, M1
Michałkiewicz, J1
Jarmuek, W1
Woźniewicz, B1
Grenda, R1
Iwanicka, K1
Madaliński, K1
Corbacioglu, S1
Eber, S1
Gungor, T1
Hummerjohann, J1
Niggli, F1
Frickhofen, N1
Märker-Hermann, E1
Reiter, A1
Walz, C1
Jung, B1
Bauer, H1
Hochhaus, A1
Isoda, A1
Hatsumi, N1
Ogawa, Y1
Matsumoto, M1
Sawamura, M1
Pullen, J1
Boyett, J1
Shuster, J1
Crist, W1
Land, V1
Frankel, L1
Iyer, R1
Backstrom, L1
van Eys, J1
Harris, M1
Hoelzer, D1
Ludwig, WD1
Thiel, E1
Gassmann, W1
Löffler, H1
Fonatsch, C1
Rieder, H1
Heil, G1
Heinze, B1
Arnold, R1
Hossfeld, D1
Büchner, T1
Koch, P1
Freund, M1
Hiddemann, W1
Maschmeyer, G1
Heyll, A1
Aul, C1
Faak, T1
Kuse, R1
Ittel, TH1
Gramatzki, M1
Diedrich, H1
Kolbe, K1
Fuhr, HG1
Fischer, K1
Schadeck-Gressel, C1
Weiss, A1
Strohscheer, I1
Metzner, B1
Fabry, U1
Gökbuget, N1
Völkers, B1
Messerer, D1
Uberla, K1
Rivera, GK1
Hudson, MM1
Liu, Q1
Benaim, E1
Ribeiro, RC1
Crist, WM1
Pui, CH1
Kaleita, TA1
Reaman, GH1
MacLean, WE1
Sather, HN1
Whitt, JK1
Sakai, R1
Maruta, A1
Tomita, N1
Taguchi, J1
Fujisawa, S1
Ogawa, K1
Motomura, S1
Kodama, F1
Mohri, H1
Ishigatsubo, Y1
Várkonyi, J1
Zalatnai, A1
Timár, J1
Matolcsi, A1
Falus, A1
Bencsáth, M1
László, V1
Pócsik, E1
Kotlán, B1
Császár, A1
Millot, F1
Suciu, S1
Philippe, N1
Benoit, Y1
Mazingue, F1
Uyttebroeck, A1
Lutz, P1
Mechinaud, F1
Robert, A1
Boutard, P1
Marguerite, G1
Ferster, A1
Plouvier, E1
Rialland, X1
Behard, C1
Plantaz, D1
Dresse, MF1
Philippet, P1
Norton, L1
Thyss, A1
Dastugue, N1
Waterkeyn, C1
Vilmer, E1
Otten, J1
Ravandi, F1
Cortes, J1
Estrov, Z1
Thomas, D1
Giles, FJ1
Huh, YO1
Pierce, S1
O'Brien, S1
Faderl, S1
Kantarjian, HM1
Barzilai, A1
Lyakhovitsky, A1
Goldberg, I1
Meytes, D1
Trau, H1
Rudzka, E1
Holowiecki, J1
Kachel, L1
Lawniczek, T1
Pajak, J1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Burkimab:Study Multicenter of Optimization of the Treatment of LLA-B and the Burkitt's Lymphoma in Adult Patients (From 15 Years Old)[NCT00388193]Phase 220 participants (Anticipated)Interventional2006-08-31Completed
Treatment of Mature B-ALL and Burkitt Lymphoma (BL) in Adult Patients. BURKIMAB-14.[NCT05049473]Phase 2100 participants (Anticipated)Interventional2014-01-31Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

2 reviews available for prednisone and Leukemic Infiltration

ArticleYear
Intrathecal chemotherapy in lymphomatous meningitis.
    Critical reviews in oncology/hematology, 2011, Volume: 79, Issue:2

    Topics: Antibodies, Monoclonal, Murine-Derived; Antineoplastic Combined Chemotherapy Protocols; Central Nerv

2011
[Renal infiltrate by a plasmocytoïd chronic B lymphocytic leukaemia and renal failure: a rare occurrence in nephropathology. A case report and review of the literature].
    Nephrologie & therapeutique, 2011, Volume: 7, Issue:6

    Topics: Antibodies, Monoclonal, Murine-Derived; Antineoplastic Combined Chemotherapy Protocols; Biopsy; Cycl

2011

Trials

3 trials available for prednisone and Leukemic Infiltration

ArticleYear
Reinduction platform for children with first marrow relapse of acute lymphoblastic Leukemia: A Children's Oncology Group Study[corrected].
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2008, Aug-20, Volume: 26, Issue:24

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Neoplasms; Central Ne

2008
Extended triple intrathecal chemotherapy trial for prevention of CNS relapse in good-risk and poor-risk patients with B-progenitor acute lymphoblastic leukemia: a Pediatric Oncology Group study.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1993, Volume: 11, Issue:5

    Topics: Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Central Nervous System Diseases; Cyclo

1993
Value of high-dose cytarabine during interval therapy of a Berlin-Frankfurt-Munster-based protocol in increased-risk children with acute lymphoblastic leukemia and lymphoblastic lymphoma: results of the European Organization for Research and Treatment of
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2001, Apr-01, Volume: 19, Issue:7

    Topics: Actuarial Analysis; Adolescent; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Centra

2001

Other Studies

19 other studies available for prednisone and Leukemic Infiltration

ArticleYear
Acute Kidney Injury With Massively Enlarged Noncystic Kidneys.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 2020, Volume: 75, Issue:5

    Topics: Acute Kidney Injury; Adolescent; Biopsy; Diagnosis, Differential; Female; Glomerular Filtration Rate

2020
Subcutaneous Masses as an Unusual Manifestation of Relapse in a Case of Atypical Chronic Lymphocytic Leukemia with Prolymphocytoid Transformation and Complex Karyotype: A Diagnostic Dilemma and Treatment Challenge.
    The American journal of case reports, 2020, May-10, Volume: 21

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Disease Progression; Doxorub

2020
[Cutaneous involvement in T-lymphoblastic lymphoma].
    Annales de dermatologie et de venereologie, 2017, Volume: 144, Issue:4

    Topics: Acute Kidney Injury; Aged; Antineoplastic Combined Chemotherapy Protocols; Bone and Bones; Cyclophos

2017
Clinical problem-solving. Fool's Gold.
    The New England journal of medicine, 2008, Nov-06, Volume: 359, Issue:19

    Topics: Adult; Bundle-Branch Block; Dyspnea; Echocardiography; Electrocardiography; False Negative Reactions

2008
Generalized leukaemia cutis from a small cell variant of T-cell prolymphocytic leukaemia presenting with exfoliative dermatitis.
    Acta dermato-venereologica, 2009, Volume: 89, Issue:5

    Topics: Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Biopsy; Bone Marrow Examination;

2009
Central nervous system complications during treatment of acute lymphoblastic leukemia in a single pediatric institution.
    Leukemia & lymphoma, 2010, Volume: 51, Issue:6

    Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Central Nervous System; Ce

2010
Successful allogeneic hematopoietic stem cell transplantation for aggressive NK cell leukemia.
    Internal medicine (Tokyo, Japan), 2010, Volume: 49, Issue:17

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Brain; Combined Modality Therap

2010
Tubulointerstitial nephritis with uveitis: clinico-pathological and immunological study.
    Pediatric nephrology (Berlin, Germany), 2002, Volume: 17, Issue:8

    Topics: Adrenal Cortex Hormones; Adult; CD3 Complex; CD4 Lymphocyte Count; CD8-Positive T-Lymphocytes; Flow

2002
Induction of long-term remission of a relapsed childhood B-acute lymphoblastic leukemia with rituximab chimeric anti-CD20 monoclonal antibody and autologous stem cell transplantation.
    Journal of pediatric hematology/oncology, 2003, Volume: 25, Issue:4

    Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Murine-Derived; Antigens, CD20; Antigens, Neoplasm;

2003
Complete molecular remission of chronic eosinophilic leukemia complicated by CNS disease after targeted therapy with imatinib.
    Annals of hematology, 2004, Volume: 83, Issue:7

    Topics: Adult; Antineoplastic Agents; Arm; Azathioprine; Benzamides; Brain; Cerebellar Ataxia; Cerebellar Co

2004
Rapid bone marrow dissemination after surgery in localized gastric diffuse large B-cell lymphoma: a case report.
    International journal of hematology, 2006, Volume: 84, Issue:5

    Topics: Aged; Antibodies, Monoclonal; Antibodies, Monoclonal, Murine-Derived; Antineoplastic Combined Chemot

2006
Improved outcome in adult B-cell acute lymphoblastic leukemia.
    Blood, 1996, Jan-15, Volume: 87, Issue:2

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Diseases; Bone

1996
Improved outcome in adult B-cell acute lymphoblastic leukemia.
    Blood, 1996, Jan-15, Volume: 87, Issue:2

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Diseases; Bone

1996
Improved outcome in adult B-cell acute lymphoblastic leukemia.
    Blood, 1996, Jan-15, Volume: 87, Issue:2

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Diseases; Bone

1996
Improved outcome in adult B-cell acute lymphoblastic leukemia.
    Blood, 1996, Jan-15, Volume: 87, Issue:2

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Diseases; Bone

1996
Effectiveness of intensified rotational combination chemotherapy for late hematologic relapse of childhood acute lymphoblastic leukemia.
    Blood, 1996, Aug-01, Volume: 88, Issue:3

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Child; Combined Mod

1996
Neurodevelopmental outcome of infants with acute lymphoblastic leukemia: a Children's Cancer Group report.
    Cancer, 1999, Apr-15, Volume: 85, Issue:8

    Topics: Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Brain Damage, Chronic; Cognition Disor

1999
Improvement of quality of life after splenectomy in an HTLV-I carrier with T-cell prolymphocytic leukemia.
    Leukemia & lymphoma, 1999, Volume: 35, Issue:5-6

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Carrier State; Combined Modality Therapy; Cyc

1999
Secondary cutaneous infiltration in B cell chronic lymphocytic leukemia.
    Acta haematologica, 2000, Volume: 103, Issue:2

    Topics: Antineoplastic Combined Chemotherapy Protocols; Chlorambucil; Cyclophosphamide; Doxorubicin; Histidi

2000
CD56 expression predicts occurrence of CNS disease in acute lymphoblastic leukemia.
    Leukemia research, 2002, Volume: 26, Issue:7

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Biomarke

2002
Aleukemic monocytic leukemia cutis.
    Cutis, 2002, Volume: 69, Issue:4

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Examination; Cyclophosphamide; Dox

2002
Skin manifestation of extramedullary relapse in adult with acute lymphoblastic leukaemia.
    Haematologia, 1991, Volume: 24, Issue:4

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Cyclophosphamide; C

1991