Page last updated: 2024-11-07

prednisone and Leukemia, Prolymphocytic

prednisone has been researched along with Leukemia, Prolymphocytic in 12 studies

Prednisone: A synthetic anti-inflammatory glucocorticoid derived from CORTISONE. It is biologically inert and converted to PREDNISOLONE in the liver.
prednisone : A synthetic glucocorticoid drug that is particularly effective as an immunosuppressant, and affects virtually all of the immune system. Prednisone is a prodrug that is converted by the liver into prednisolone (a beta-hydroxy group instead of the oxo group at position 11), which is the active drug and also a steroid.

Leukemia, Prolymphocytic: A chronic leukemia characterized by a large number of circulating prolymphocytes. It can arise spontaneously or as a consequence of transformation of CHRONIC LYMPHOCYTIC LEUKEMIA.

Research Excerpts

ExcerptRelevanceReference
"To describe the results of fludarabine therapy in patients with prolymphocytic leukemia (PLL) and the prolymphocytoid variant of chronic lymphocytic leukemia (CLL-Pro)."9.07Efficacy of fludarabine, a new adenine nucleoside analogue, in patients with prolymphocytic leukemia and the prolymphocytoid variant of chronic lymphocytic leukemia. ( Beran, M; Childs, C; Huh, Y; Kantarjian, HM; Keating, MJ; Koller, C; O'Brien, S; Schachner, J, 1991)
"To describe the results of fludarabine therapy in patients with prolymphocytic leukemia (PLL) and the prolymphocytoid variant of chronic lymphocytic leukemia (CLL-Pro)."5.07Efficacy of fludarabine, a new adenine nucleoside analogue, in patients with prolymphocytic leukemia and the prolymphocytoid variant of chronic lymphocytic leukemia. ( Beran, M; Childs, C; Huh, Y; Kantarjian, HM; Keating, MJ; Koller, C; O'Brien, S; Schachner, J, 1991)
"Although hypercalcemia is more frequently found in T-cell leukaemia associated with human T lymphotropic lymphocyte type I, scattered reports indicate that patients with B-CLL can also be affected with this metabolic disturbance."2.39B-CLL in PLL transformation associated with hypercalcemia. ( De Oliveira, MS; Esteves, C; Lerner, D, 1994)

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19901 (8.33)18.7374
1990's8 (66.67)18.2507
2000's3 (25.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Murase, K1
Matsunaga, T1
Sato, T1
Kuribayashi, K1
Kogawa, K1
Kawano, Y1
Okamoto, T1
Takayama, T1
Watanabe, H1
Niitsu, Y1
Hirayama, Y1
de Lavallade, H1
Faucher, C1
Fürst, S1
El-Cheikh, J1
Vey, N1
Coso, D1
Bouabdallah, R1
Stoppa, AM1
Gastaut, JA1
Blaise, D1
Mohty, M1
Crisostomo, RH1
Fernandez, JA1
Caceres, W1
Witzig, TE1
Weitz, JJ1
Lundberg, JH1
Tefferi, A1
Lerner, D1
Esteves, C1
De Oliveira, MS1
Yuen, BH1
Godwin, JE1
Jones, R1
Pipas, JM1
Kritz, AD1
Akin, C1
Hansen, P1
Janckila, A1
Sakai, R1
Maruta, A1
Tomita, N1
Taguchi, J1
Fujisawa, S1
Ogawa, K1
Motomura, S1
Kodama, F1
Mohri, H1
Ishigatsubo, Y1
Kantarjian, HM1
Childs, C1
O'Brien, S1
Huh, Y1
Beran, M1
Schachner, J1
Koller, C1
Keating, MJ1
Bisail, M1
Cassisa, L1
Manca, M1
Casula, S1
Fele, G1
Malavasi, A1
De Belilovsky, C1
Guillaume, JC1
Gilles, E1
Bosq, J1
Hayat, M1
Desvignes, V1
Avril, MF1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Treatment of T-Large Granular Lymphocyte (T-LGL) Lymphoproliferative Disorders With Cyclosporine[NCT00001533]Phase 125 participants Interventional1996-09-30Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for prednisone and Leukemia, Prolymphocytic

ArticleYear
B-CLL in PLL transformation associated with hypercalcemia.
    Leukemia & lymphoma, 1994, Volume: 12, Issue:3-4

    Topics: Antigens, CD; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Chlorambucil; Cyclophosph

1994

Trials

1 trial available for prednisone and Leukemia, Prolymphocytic

ArticleYear
Efficacy of fludarabine, a new adenine nucleoside analogue, in patients with prolymphocytic leukemia and the prolymphocytoid variant of chronic lymphocytic leukemia.
    The American journal of medicine, 1991, Volume: 90, Issue:2

    Topics: Aged; Aged, 80 and over; Agranulocytosis; Antineoplastic Agents; Chromosome Aberrations; Chromosome

1991

Other Studies

10 other studies available for prednisone and Leukemia, Prolymphocytic

ArticleYear
Allogeneic bone marrow transplantation in a patient with T-prolymphocytic leukemia with small-intestinal involvement.
    International journal of clinical oncology, 2003, Volume: 8, Issue:6

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Cyclophosphamide

2003
Allogeneic stem cell transplantation after reduced-intensity conditioning in a patient with T-cell prolymphocytic leukemia: graft-versus-tumor effect and long-term remission.
    Bone marrow transplantation, 2006, Volume: 37, Issue:7

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Doxorubicin; Follow-Up Stud

2006
Complex karyotype including chromosomal translocation (8;14) (q24;q32) in one case with B-cell prolymphocytic leukemia.
    Leukemia research, 2007, Volume: 31, Issue:5

    Topics: Antineoplastic Combined Chemotherapy Protocols; Chromosome Aberrations; Chromosomes, Human, Pair 14;

2007
Treatment of refractory T-cell chronic lymphocytic leukemia with purine nucleoside analogues.
    Leukemia & lymphoma, 1994, Volume: 14, Issue:1-2

    Topics: 2-Chloroadenosine; Anemia; Antineoplastic Combined Chemotherapy Protocols; CD3 Complex; CD4-Positive

1994
ProMACE day 1/MOPP day 8 chemotherapy for prolymphocytic leukemia: a case report of prolonged survival.
    American journal of hematology, 1994, Volume: 46, Issue:3

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Doxorubicin; Drug Administra

1994
Tumor lysis syndrome provides evidence for dose-intense response for corticosteroids in prolymphocytic leukemia.
    Blood, 1993, Feb-15, Volume: 81, Issue:4

    Topics: Aged; Aged, 80 and over; Humans; Leukemia, Prolymphocytic; Male; Prednisone; Tumor Lysis Syndrome

1993
Prolymphocytic leukemia: diagnosis and treatment. A case report.
    The Journal of the Kentucky Medical Association, 1997, Volume: 95, Issue:11

    Topics: Antineoplastic Combined Chemotherapy Protocols; B-Lymphocytes; Biopsy, Needle; Bone Marrow; Combined

1997
Improvement of quality of life after splenectomy in an HTLV-I carrier with T-cell prolymphocytic leukemia.
    Leukemia & lymphoma, 1999, Volume: 35, Issue:5-6

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Carrier State; Combined Modality Therapy; Cyc

1999
[Discordance between clinical and immunological aspects in a case of chronic B-type lymphoproliferative syndrome].
    Minerva medica, 1991, Volume: 82, Issue:6

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; B-Lymphocytes; Chronic Disease; Cyclophosphami

1991
[Cutaneous manifestations of T-cell prolymphocytic leukemia].
    Annales de dermatologie et de venereologie, 1989, Volume: 116, Issue:11

    Topics: Antineoplastic Combined Chemotherapy Protocols; Back; Cyclophosphamide; Doxorubicin; Follow-Up Studi

1989