Page last updated: 2024-11-07

prednisone and Labor, Premature

prednisone has been researched along with Labor, Premature in 12 studies

Prednisone: A synthetic anti-inflammatory glucocorticoid derived from CORTISONE. It is biologically inert and converted to PREDNISOLONE in the liver.
prednisone : A synthetic glucocorticoid drug that is particularly effective as an immunosuppressant, and affects virtually all of the immune system. Prednisone is a prodrug that is converted by the liver into prednisolone (a beta-hydroxy group instead of the oxo group at position 11), which is the active drug and also a steroid.

Research Excerpts

ExcerptRelevanceReference
"8 mg per kilogram of body weight per day) and aspirin (100 mg per day) or placebo for the duration of the pregnancy."5.08Prednisone and aspirin in women with autoantibodies and unexplained recurrent fetal loss. ( Bombardier, C; Farewell, V; Farine, D; Fielding, L; Hannah, ME; Laskin, CA; Mandel, FP; Ritchie, JW; Soloninka, CA; Spitzer, K; Yeung, M, 1997)
"We compared the use of aspirin alone with combined therapy (prednisone plus aspirin) in antiphospholipid antibody-positive obstetric patients with prior adverse pregnancy outcome."5.07Comparative trial of prednisone plus aspirin versus aspirin alone in the treatment of anticardiolipin antibody-positive obstetric patients. ( Hobart, JM; MacGregor, SN; Neerhof, MG; Ragin, A; Sholl, JS; Silver, RK, 1993)
"A pregnant patient developed fulminant polymyositis with myoglobinuria after terbutaline and magnesium sulfate tocolysis."4.77Polymyositis with myoglobinuria in pregnancy: a report and review of the literature. ( Ditzian-Kadanoff, R; Reinhard, JD; Segal, AS; Thomas, C, 1988)
" We recorded demographic data, disease activity (SLE Disease Activity Index, SLEDAI), obstetric history, prednisone dosage, other medications taken during pregnancy, history of renal disease, and autoantibody status [including antinuclear antibody, anti-DNA, anticardiolipin IgG (aCL), and lupus anticoagulant (LAC)]."3.72Preterm deliveries in women with systemic lupus erythematosus. ( Clark, CA; Laskin, CA; Nadler, JN; Spitzer, KA, 2003)
"An autoimmune disease was present in seven (29%) cases."1.42Chronic histiocytic intervillositis: outcome, associated diseases and treatment in a multicenter prospective study. ( Botta, A; Bucourt, M; Carbillon, L; Chollet-Martin, S; Chudzinski, A; Cornelis, F; Costedoat-Chalumeau, N; De Carolis, S; Emmanuelli, V; Fain, O; Hachulla, E; Masseau, A; Mekinian, A; Montestruc, F; Nicaise, P; Revaux, A; Subtil, D; Theulin, A, 2015)
"Pregnancy was authorized if disease was inactive on 20 mg/day prednisone or less for at least 1 yr."1.30Outcome of planned pregnancies in systemic lupus erythematosus: a prospective study on 62 pregnancies. ( Blétry, O; Darbois, Y; Godeau, P; Lê Huong, D; Lefèbvre, G; Piette, JC; Seebacher, J; Vauthier-Brouzes, D; Wechsler, B, 1997)
"Mean birth weight was 2."1.28[Pregnancy after renal transplantation. 27 patients and review of the literature]. ( Edouard, D; Fernandez, H; Frydman, R; Ville, Y, 1992)
"Most frequent are preeclampsia, premature labour, foetal maldevelopment and flare-ups of the underlying disease."1.28[Systemic lupus erythematosus and pregnancy. Clinical aspects, serology and management]. ( DuBois, A; Hillemanns, HG; Kerl, J; Quaas, L; Röther, E; Runge, HM, 1990)
"Pregnancy was best tolerated by mothers without significant nephropathy or cardiopathy who had been in clinical remission for more than three months prior to conception."1.26Systemic lupus erythematosus in pregnancy. ( Devoe, LD; Taylor, RL, 1979)

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19902 (16.67)18.7374
1990's6 (50.00)18.2507
2000's1 (8.33)29.6817
2010's3 (25.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Mekinian, A1
Costedoat-Chalumeau, N1
Masseau, A1
Botta, A1
Chudzinski, A1
Theulin, A1
Emmanuelli, V1
Hachulla, E1
De Carolis, S1
Revaux, A1
Nicaise, P1
Cornelis, F1
Subtil, D1
Montestruc, F1
Bucourt, M1
Chollet-Martin, S1
Carbillon, L1
Fain, O1
Sung, N1
Byeon, HJ1
Garcia, MDS1
Skariah, A1
Wu, L1
Dambaeva, S1
Beaman, K1
Gilman-Sachs, A1
Kwak-Kim, J1
Klehmet, J1
Dudenhausen, J1
Meisel, A1
Clark, CA1
Spitzer, KA1
Nadler, JN1
Laskin, CA2
Silver, RK1
MacGregor, SN1
Sholl, JS1
Hobart, JM1
Neerhof, MG1
Ragin, A1
Bombardier, C1
Hannah, ME1
Mandel, FP1
Ritchie, JW1
Farewell, V1
Farine, D1
Spitzer, K1
Fielding, L1
Soloninka, CA1
Yeung, M1
Lê Huong, D1
Wechsler, B1
Vauthier-Brouzes, D1
Seebacher, J1
Lefèbvre, G1
Blétry, O1
Darbois, Y1
Godeau, P1
Piette, JC1
Devoe, LD1
Taylor, RL1
Ville, Y1
Fernandez, H1
Edouard, D1
Frydman, R1
Cowchock, FS1
Reece, EA1
Balaban, D1
Branch, DW1
Plouffe, L1
Runge, HM1
Röther, E1
Kerl, J1
DuBois, A1
Quaas, L1
Hillemanns, HG1
Ditzian-Kadanoff, R1
Reinhard, JD1
Thomas, C1
Segal, AS1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Low Dose Prednisone Therapy in Women With Recurrent Pregnancy Loss[NCT04558268]Phase 2/Phase 3242 participants (Anticipated)Interventional2020-12-31Not yet recruiting
Certolizumab to Prevent Pregnancy Complications in High-Risk Patients With APS or SLE - (IMPACT Study: IMProve Pregnancy in APS With Certolizumab Therapy)[NCT03152058]Phase 255 participants (Anticipated)Interventional2017-05-17Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

2 reviews available for prednisone and Labor, Premature

ArticleYear
[Course and treatment of myasthenia gravis during pregnancy].
    Der Nervenarzt, 2010, Volume: 81, Issue:8

    Topics: Adult; Anti-Inflammatory Agents; Arthrogryposis; Autoantibodies; Breast Feeding; Cesarean Section; C

2010
Polymyositis with myoglobinuria in pregnancy: a report and review of the literature.
    The Journal of rheumatology, 1988, Volume: 15, Issue:3

    Topics: Adult; Female; Humans; Magnesium Sulfate; Myoglobinuria; Myositis; Obstetric Labor, Premature; Predn

1988

Trials

3 trials available for prednisone and Labor, Premature

ArticleYear
Comparative trial of prednisone plus aspirin versus aspirin alone in the treatment of anticardiolipin antibody-positive obstetric patients.
    American journal of obstetrics and gynecology, 1993, Volume: 169, Issue:6

    Topics: Adult; Antibodies, Anticardiolipin; Antiphospholipid Syndrome; Aspirin; Drug Therapy, Combination; F

1993
Prednisone and aspirin in women with autoantibodies and unexplained recurrent fetal loss.
    The New England journal of medicine, 1997, Jul-17, Volume: 337, Issue:3

    Topics: Abortion, Habitual; Adolescent; Adult; Aspirin; Autoantibodies; Female; Fetal Membranes, Premature R

1997
Repeated fetal losses associated with antiphospholipid antibodies: a collaborative randomized trial comparing prednisone with low-dose heparin treatment.
    American journal of obstetrics and gynecology, 1992, Volume: 166, Issue:5

    Topics: Abortion, Habitual; Antiphospholipid Syndrome; Female; Fetal Membranes, Premature Rupture; Heparin;

1992

Other Studies

7 other studies available for prednisone and Labor, Premature

ArticleYear
Chronic histiocytic intervillositis: outcome, associated diseases and treatment in a multicenter prospective study.
    Autoimmunity, 2015, Volume: 48, Issue:1

    Topics: Abortion, Habitual; Adult; Aspirin; Autoantibodies; Autoimmune Diseases; Cell Movement; Chorionic Vi

2015
Deficiency in memory B cell compartment in a patient with infertility and recurrent pregnancy losses.
    Journal of reproductive immunology, 2016, Volume: 118

    Topics: Abortion, Habitual; Adult; Antigens, CD19; B-Lymphocyte Subsets; B-Lymphocytes; Female; Humans; Immu

2016
Preterm deliveries in women with systemic lupus erythematosus.
    The Journal of rheumatology, 2003, Volume: 30, Issue:10

    Topics: Anti-Inflammatory Agents; Antibodies, Anticardiolipin; Female; Humans; Infant, Newborn; Lupus Erythe

2003
Outcome of planned pregnancies in systemic lupus erythematosus: a prospective study on 62 pregnancies.
    British journal of rheumatology, 1997, Volume: 36, Issue:7

    Topics: Adrenal Cortex Hormones; Aging; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; A

1997
Systemic lupus erythematosus in pregnancy.
    American journal of obstetrics and gynecology, 1979, Oct-15, Volume: 135, Issue:4

    Topics: Abortion, Induced; Abortion, Missed; Azathioprine; Female; Humans; Infant, Newborn; Lupus Erythemato

1979
[Pregnancy after renal transplantation. 27 patients and review of the literature].
    Journal de gynecologie, obstetrique et biologie de la reproduction, 1992, Volume: 21, Issue:6

    Topics: Adult; Azathioprine; Birth Weight; Cesarean Section; Cyclosporine; Drug Therapy, Combination; Female

1992
[Systemic lupus erythematosus and pregnancy. Clinical aspects, serology and management].
    Geburtshilfe und Frauenheilkunde, 1990, Volume: 50, Issue:7

    Topics: Antibodies, Antinuclear; Azathioprine; Female; Fetal Death; Humans; Infant, Newborn; Lupus Erythemat

1990