prednisone has been researched along with Intraocular Pressure in 52 studies
Prednisone: A synthetic anti-inflammatory glucocorticoid derived from CORTISONE. It is biologically inert and converted to PREDNISOLONE in the liver.
prednisone : A synthetic glucocorticoid drug that is particularly effective as an immunosuppressant, and affects virtually all of the immune system. Prednisone is a prodrug that is converted by the liver into prednisolone (a beta-hydroxy group instead of the oxo group at position 11), which is the active drug and also a steroid.
Intraocular Pressure: The pressure of the fluids in the eye.
| Excerpt | Relevance | Reference |
|---|---|---|
| "These results suggest that fluocinolone acetonide implant therapy is associated with a clinically important increased risk of glaucoma and cataract with respect to systemic therapy, suggesting that careful monitoring and early intervention to prevent glaucoma is warranted with implant therapy." | 9.20 | Quality of Life and Risks Associated with Systemic Anti-inflammatory Therapy versus Fluocinolone Acetonide Intraocular Implant for Intermediate Uveitis, Posterior Uveitis, or Panuveitis: Fifty-four-Month Results of the Multicenter Uveitis Steroid Treatmen ( , 2015) |
| "These results suggest that fluocinolone acetonide implant therapy is associated with a clinically important increased risk of glaucoma and cataract with respect to systemic therapy, suggesting that careful monitoring and early intervention to prevent glaucoma is warranted with implant therapy." | 5.20 | Quality of Life and Risks Associated with Systemic Anti-inflammatory Therapy versus Fluocinolone Acetonide Intraocular Implant for Intermediate Uveitis, Posterior Uveitis, or Panuveitis: Fifty-four-Month Results of the Multicenter Uveitis Steroid Treatmen ( , 2015) |
| "The perioperative use of oral prednisone did not alter the surgical outcome of filtering procedures associated with antifibrosis agents in this population of glaucoma patients." | 5.09 | Oral prednisone in guarded filtration procedures supplemented with antimetabolites. ( Augsburger, JJ; Azuara-Blanco, A; Spaeth, GL, 1999) |
| " The main outcome measures were prevalence of cataracts and elevated IOP, age of first detection of cataract, time from initial steroid use to first detection of cataract, and relative risk of cataract development for deflazacort versus prednisone treatment." | 3.88 | Cataract development associated with long-term glucocorticoid therapy in Duchenne muscular dystrophy patients. ( Horn, PS; Rice, ML; Wong, B; Yang, MB, 2018) |
| "This prospective non-comparative case series followed 77 eyes of 63 patients which showed signs of threatened early bleb failure and were treated with oral anti-inflammatory fibrosis suppression of prednisone, a non-steroidal anti-inflammatory agent, and colchicine taken for a mean period of 6 weeks, in addition to standard postoperative topical treatment, for a mean follow up of 6 years." | 3.71 | Anti-inflammatory fibrosis suppression in threatened trabeculectomy bleb failure produces good long term control of intraocular pressure without risk of sight threatening complications. ( Bevin, TH; Fuller, JR; Herbison, P; Molteno, AC; Vote, BJ, 2002) |
| "A 38-year-old physician presented with a 9-month history of progressive self-administration of oral prednisone < or = 160 mg per day for Addison's disease." | 3.69 | Exophthalmos and iatrogenic Cushing's syndrome. ( Panzer, SW; Patrinely, JR; Wilson, HK, 1994) |
| "The mean systemic prednisone (or equivalent) dosage significantly decreased at 3- and 6-month follow-up evaluations compared to baseline (P = 0." | 1.46 | Systemic Steroid Sparing Effect of Intravitreal Dexamethasone Implant in Chronic Noninfectious Uveitic Macular Edema. ( Bacherini, D; Cantarini, L; Emmi, G; Fabiani, C; Favale, RA; Franceschini, R; Frediani, B; Fusco, F; Galeazzi, M; Guerriero, S; Iannone, F; Lopalco, G; Tosi, GM; Vannozzi, L; Vitale, A, 2017) |
| "Sarcoidosis was confirmed by biopsy of an enlarged parotid gland." | 1.29 | Posterior scleritis with annular ciliochoroidal detachment. ( Barnhorst, DA; Caravella, LP; Dodds, EM; Lavertu, P; Lowder, CY; White, DE, 1995) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 26 (50.00) | 18.7374 |
| 1990's | 9 (17.31) | 18.2507 |
| 2000's | 6 (11.54) | 29.6817 |
| 2010's | 11 (21.15) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kaden, TR | 1 |
| Freund, KB | 1 |
| Engelbert, M | 1 |
| Prasad, D | 1 |
| Poddar, U | 1 |
| Kanaujia, V | 1 |
| Yachha, SK | 1 |
| Srivastava, A | 1 |
| Agranat, JS | 1 |
| Moussa, K | 1 |
| Aronow, ME | 1 |
| Fabiani, C | 1 |
| Vitale, A | 1 |
| Emmi, G | 1 |
| Lopalco, G | 1 |
| Vannozzi, L | 1 |
| Bacherini, D | 1 |
| Guerriero, S | 1 |
| Favale, RA | 1 |
| Fusco, F | 1 |
| Franceschini, R | 1 |
| Frediani, B | 1 |
| Iannone, F | 1 |
| Galeazzi, M | 1 |
| Tosi, GM | 1 |
| Cantarini, L | 1 |
| Rice, ML | 1 |
| Wong, B | 1 |
| Horn, PS | 1 |
| Yang, MB | 1 |
| Birnbaum, FA | 1 |
| Finn, AP | 1 |
| Jaffe, GJ | 1 |
| Gomes, BF | 1 |
| Moraes, HV | 1 |
| Kara-Junior, N | 1 |
| de Azevedo, MN | 1 |
| Fonyat de Lima, FB | 1 |
| Santhiago, MR | 1 |
| Pollock, T | 1 |
| Laliberté, I | 1 |
| Wu, J | 1 |
| Lyons, C | 1 |
| Tanaka-Kitajima, N | 1 |
| Iwata, N | 1 |
| Ando, Y | 1 |
| Sakurai, H | 1 |
| Iwami, M | 1 |
| Tsuzuki, K | 1 |
| Kondo, M | 1 |
| Ito, Y | 1 |
| Kimura, H | 1 |
| Oono, S | 1 |
| Kurimoto, T | 1 |
| Oku, H | 1 |
| Mimura, O | 1 |
| Cristol, SM | 1 |
| Baumblatt, JG | 1 |
| Icasiano, E | 1 |
| Grajewski, AL | 1 |
| Olivier, MM | 1 |
| Parrish, RK | 1 |
| Payne, JF | 1 |
| Srivastava, SK | 1 |
| Wells, JR | 1 |
| Grossniklaus, HE | 1 |
| Le-Nguyen, XT | 1 |
| Lee, TK | 1 |
| Do, DV | 1 |
| Sepah, YJ | 1 |
| Nguyen, QD | 1 |
| Rao, NA | 1 |
| Vasconcelos-Santos, DV | 1 |
| Goldstein, DA | 1 |
| Fuller, JR | 1 |
| Bevin, TH | 1 |
| Molteno, AC | 3 |
| Vote, BJ | 1 |
| Herbison, P | 1 |
| Friling, R | 1 |
| Weinberger, D | 1 |
| Zeharia, A | 1 |
| Lusky, M | 1 |
| Mimouni, M | 1 |
| Gaaton, D | 1 |
| Snir, M | 1 |
| BERNSTEIN, HN | 1 |
| SCHWARTZ, B | 1 |
| LERMAN, S | 1 |
| SHEVALEV, AI | 1 |
| SPIERS, F | 1 |
| LINNER, E | 1 |
| Slansky, HH | 1 |
| Kolbert, G | 1 |
| Gartner, S | 1 |
| Ancker, E | 1 |
| Van Biljon, G | 1 |
| Dodds, EM | 1 |
| Lowder, CY | 1 |
| Barnhorst, DA | 1 |
| Lavertu, P | 1 |
| Caravella, LP | 1 |
| White, DE | 1 |
| Panzer, SW | 1 |
| Patrinely, JR | 1 |
| Wilson, HK | 1 |
| Kurtz, S | 1 |
| Moisseiev, J | 1 |
| Gutman, I | 1 |
| Blumenthal, M | 1 |
| Vuori, ML | 1 |
| Stidham, DB | 1 |
| Sondhi, N | 1 |
| Plager, D | 1 |
| Helveston, E | 1 |
| Azuara-Blanco, A | 1 |
| Spaeth, GL | 1 |
| Augsburger, JJ | 1 |
| Derzko-Dzulynsky, L | 1 |
| Rabinovitch, T | 1 |
| Pavlin, CR | 1 |
| deVeber, GA | 1 |
| Cook, GT | 1 |
| Chisholm, LD | 1 |
| Gardner, RC | 1 |
| Janik, J | 2 |
| Mroczek-Madziar, D | 1 |
| Zgliczyński, S | 2 |
| Górowski, T | 2 |
| Jastrzebska, H | 2 |
| Sek, S | 1 |
| Wasowska, M | 1 |
| Kahaly, G | 1 |
| Böckmann, H | 1 |
| Beyer, J | 1 |
| Bischoff, S | 1 |
| Mitchell, DJ | 1 |
| Steahly, LP | 1 |
| Astle, JN | 1 |
| Ellis, PP | 1 |
| Phelps, CD | 1 |
| Harrington, DO | 1 |
| Levenson, JE | 1 |
| Brightbill, FS | 1 |
| Godel, V | 1 |
| Feiler-Ofry, V | 1 |
| Stein, R | 1 |
| Bellows, AR | 1 |
| Grant, WM | 1 |
| Schwartz, A | 1 |
| Sugar, HS | 1 |
| Dugmore, W | 1 |
| Prus-Sawicka, K | 2 |
| Giles, CL | 1 |
| Milstein, BA | 1 |
| Morretin, LB | 1 |
| Kristensen, P | 1 |
| Diotallevi, M | 1 |
| Bocci, N | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| The Effect of Inhaled Corticosteroids on Intraocular Pressure in Patients With Ocular Hypertension or Controlled Glaucoma.[NCT02338362] | Phase 4 | 22 participants (Actual) | Interventional | 2014-09-30 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Adherence was calculated from self-reported study diaries and correlated to a counter that measured number of inhaled puffs built into the placebo metered-dose inhalers (NCT02338362)
Timeframe: Completion of study, up to 6 weeks
| Intervention | percentage of required doses (Mean) |
|---|---|
| Fluticasone | 93.6 |
| Saline Placebo | 96.1 |
Masked assessment of intraocular pressure using goldmann application tonometry. Mean of 2 measurements within 1 mmHg will be recorded. (NCT02338362)
Timeframe: week 6
| Intervention | mmHg (Mean) |
|---|---|
| Fluticasone | 14.7 |
| Saline Placebo | 14.8 |
best corrected logMAR visual acuity for each eye. 20/20 vision corresponds with a logMAR score of 0, while negative logMAR scores indicate better than 20/20 vision, values > 0.5 correspond with low vision, and values > 1.3 correspond with blindness. (NCT02338362)
Timeframe: week 6
| Intervention | logMAR (Mean) |
|---|---|
| Fluticasone | 0.15 |
| Saline Placebo | 0.15 |
Participants with 2 consecutive intraocular pressure measurements exceeding 20% increase from baseline were discontinued from study. (NCT02338362)
Timeframe: within 6-week observation period
| Intervention | participants (Number) | |
|---|---|---|
| elevation >20% | no elevation >20% | |
| Fluticasone | 1 | 9 |
| Saline Placebo | 0 | 10 |
subjective (reported) and objective (slit lamp examination) side-effects attributable to study medications (NCT02338362)
Timeframe: from baseline to week 6
| Intervention | participants (Number) | ||||
|---|---|---|---|---|---|
| lens opacity | throat discomfort | headache | difficulty sleeping | no adverse effects | |
| Fluticasone | 0 | 1 | 1 | 0 | 8 |
| Saline Placebo | 0 | 1 | 0 | 1 | 8 |
1 review available for prednisone and Intraocular Pressure
| Article | Year |
|---|---|
[HORMONE THERAPY AS A CAUSE OF TRANSITORY OCULAR HYPERTENSION AND GLAUCOMA].
Topics: Adrenocorticotropic Hormone; Cats; Cortisone; Estrone; Glaucoma; Hormones; Intraocular Pressure; Man | 1963 |
2 trials available for prednisone and Intraocular Pressure
| Article | Year |
|---|---|
Quality of Life and Risks Associated with Systemic Anti-inflammatory Therapy versus Fluocinolone Acetonide Intraocular Implant for Intermediate Uveitis, Posterior Uveitis, or Panuveitis: Fifty-four-Month Results of the Multicenter Uveitis Steroid Treatmen
Topics: Adult; Aged; Anti-Inflammatory Agents; Cataract; Drug Implants; Female; Fluocinolone Acetonide; Foll | 2015 |
Oral prednisone in guarded filtration procedures supplemented with antimetabolites.
Topics: Administration, Oral; Aged; Chemotherapy, Adjuvant; Double-Blind Method; Female; Filtering Surgery; | 1999 |
49 other studies available for prednisone and Intraocular Pressure
| Article | Year |
|---|---|
Choroidal Effusion after Laser Peripheral Iridotomy.
Topics: Choroidal Effusions; Female; Glaucoma, Angle-Closure; Glucocorticoids; Humans; Intraocular Pressure; | 2019 |
Effect of Long-term Oral Steroids on Intraocular Pressure in Children With Autoimmune Hepatitis: a Prospective Cohort Study.
Topics: Administration, Oral; Adolescent; Antihypertensive Agents; Child; Child, Preschool; Female; Follow-U | 2019 |
An Amelanotic Choroidal Mass in a Middle-aged Woman.
Topics: Choroid Neoplasms; Female; Fluorescein Angiography; Glucocorticoids; Humans; Intraocular Pressure; M | 2019 |
Systemic Steroid Sparing Effect of Intravitreal Dexamethasone Implant in Chronic Noninfectious Uveitic Macular Edema.
Topics: Chronic Disease; Dexamethasone; Drug Implants; Female; Fluorescein Angiography; Glucocorticoids; Hum | 2017 |
Cataract development associated with long-term glucocorticoid therapy in Duchenne muscular dystrophy patients.
Topics: Adolescent; Cataract; Cataract Extraction; Child; Female; Glucocorticoids; Humans; Immunosuppressive | 2018 |
Bilateral Retinal Detachments Presenting With Acute Angle Closure.
Topics: Female; Fluorescein Angiography; Glaucoma, Angle-Closure; Glucocorticoids; Humans; Intraocular Press | 2018 |
Intraocular pressure in chronic users of low-dose oral corticosteroids for connective tissue disease.
Topics: Administration, Oral; Connective Tissue Diseases; Cross-Sectional Studies; Female; Glucocorticoids; | 2014 |
Traumatic hyphema and immune thrombocytopenic purpura: late rebleeds associated with low platelet count.
Topics: Anterior Eye Segment; Child, Preschool; Combined Modality Therapy; Dexamethasone; Eye Injuries; Huma | 2008 |
Acute retinal necrosis caused by herpes simplex virus type 2 in a 3-year-old Japanese boy.
Topics: Acyclovir; Anti-Inflammatory Agents; Antiviral Agents; Child, Preschool; Disease Progression; Drug T | 2009 |
Adult T-cell leukemia presenting with episcleritis and secondary glaucoma.
Topics: Antihypertensive Agents; Antineoplastic Combined Chemotherapy Protocols; Betamethasone; Conjunctivit | 2009 |
Bilateral acute angle-closure associated with systemic lymphoma: a report of 2 cases.
Topics: Acute Disease; Aged; Antihypertensive Agents; Antineoplastic Combined Chemotherapy Protocols; Biopsy | 2011 |
Rosai-Dorfman disease simulating nodular scleritis and panuveitis.
Topics: Diagnosis, Differential; Female; Histiocytes; Histiocytosis, Sinus; Humans; Immunoenzyme Techniques; | 2011 |
Diagnostic and therapeutic challenges.
Topics: Adult; Amiodarone; Central Nervous System Diseases; Diagnosis, Differential; Glucocorticoids; Humans | 2011 |
Anti-inflammatory fibrosis suppression in threatened trabeculectomy bleb failure produces good long term control of intraocular pressure without risk of sight threatening complications.
Topics: Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Colchicine; Diclofenac; Dru | 2002 |
Elevated intraocular pressure associated with steroid treatment for infantile spasms.
Topics: Administration, Oral; Antihypertensive Agents; Cosyntropin; Female; Glucocorticoids; Humans; Infant; | 2003 |
Effects of long-term systemic steroids on ocular pressure and tonographic values.
Topics: Cortisone; Eye; Humans; Intraocular Pressure; Prednisone; Tonometry, Ocular | 1962 |
STEROID THERAPY AND SECONDARY GLAUCOMA.
Topics: Acetazolamide; Black People; Cataract Extraction; Glaucoma; Humans; Intraocular Pressure; Iridocycli | 1963 |
UNILATERAL ACUTE RISE IN INTRAOCULAR PRESSURE FOLLOWING LONG-TERM BILATERAL LOCAL TREATMENT WITH PREDNISONE (ULTRACORTENOL) IN A CASE OF UVEITIS.
Topics: Drug Therapy; Eye Diseases; Humans; Intraocular Pressure; Iridocyclitis; Levobunolol; Prednisone; To | 1965 |
Adrenocortical steroids and aqueous humour dynamics.
Topics: Aqueous Humor; Eye Diseases; Intraocular Pressure; Prednisone; Tonometry, Ocular | 1959 |
Exophathalmos induced by steroids.
Topics: Adult; Aged; Cataract; Exophthalmos; Female; Humans; Hydrocortisone; Hyperglycemia; Intraocular Pres | 1967 |
Surgical technique for advanced juvenile glaucoma.
Topics: Acetazolamide; Adolescent; Adult; Carbachol; Child; Child, Preschool; Colchicine; Drainage; Follow-U | 1984 |
Posterior scleritis with annular ciliochoroidal detachment.
Topics: Adrenergic beta-Antagonists; Adult; Anti-Inflammatory Agents; Biopsy; Choroid Diseases; Ciliary Body | 1995 |
Exophthalmos and iatrogenic Cushing's syndrome.
Topics: Addison Disease; Adipose Tissue; Administration, Oral; Adult; Cushing Syndrome; Exophthalmos; Humans | 1994 |
Orbital pseudotumor presenting as acute glaucoma with choroidal and retinal detachment.
Topics: Acute Disease; Aged; Choroid Diseases; Female; Glaucoma; Humans; Intraocular Pressure; Orbital Pseud | 1993 |
Recurrent severe hypotony after cataract surgery in an eye with previous trabeculectomy.
Topics: Atropine; Dexamethasone; Exfoliation Syndrome; Female; Glaucoma, Open-Angle; Glucocorticoids; Humans | 1998 |
Presumed isolated inflammation of the superior oblique muscle in idiopathic orbital myositis.
Topics: Humans; Intraocular Pressure; Male; Middle Aged; Oculomotor Muscles; Orbital Pseudotumor; Prednisone | 1998 |
Tubulointerstitial nephritis and uveitis with bilateral multifocal choroiditis.
Topics: Adolescent; Choroiditis; Female; Glaucoma; Glucocorticoids; Humans; Intraocular Pressure; Nephritis, | 2000 |
Ocular complications in renal transplant recipients.
Topics: Adolescent; Adrenal Cortex Hormones; Adult; Cataract; Female; Humans; Intraocular Pressure; Kidney T | 1977 |
Anterior vitrectomy.
Topics: Adult; Aged; Cataract Extraction; Edema; Evaluation Studies as Topic; Eye Foreign Bodies; Eye Injuri | 1975 |
[Intraocular pressure in patients with infiltrative-edematous exophthalmos in Graves' disease treated with prednisone].
Topics: Adult; Aged; Dose-Response Relationship, Drug; Exophthalmos; Female; Graves Disease; Humans; Intraoc | 1990 |
[Ocular hypertension in patients with infiltrative-edematous exophthalmos in Graves' disease].
Topics: Combined Modality Therapy; Exophthalmos; Female; Graves Disease; Humans; Intraocular Pressure; Middl | 1990 |
Long-term observation of endocrine ophthalmopathy and retrospective appraisal of therapeutic measures.
Topics: Adolescent; Adult; Aged; Autoimmune Diseases; Cyclosporins; Endocrine System Diseases; Exophthalmos; | 1990 |
Pseudotumor cerebri and macular disease.
Topics: Adult; Choroid; Diplopia; Female; Fundus Oculi; Headache; Humans; Intraocular Pressure; Macular Edem | 1989 |
Ocular complications in renal transplant patients.
Topics: Adolescent; Adult; Azathioprine; Blood Urea Nitrogen; Cataract; Child; Cyclophosphamide; Cytomegalov | 1974 |
Angle-closure glaucoma secondary to ciliary body swelling.
Topics: Acetazolamide; Adult; Anterior Chamber; Atropine; Betamethasone; Ciliary Body; Corticosterone; Dexam | 1974 |
Analysis of some unusual and difficult visual field defects.
Topics: Adolescent; Adult; Child; Craniopharyngioma; Diagnosis, Differential; Female; Fluorescein Angiograph | 1972 |
Endothelial rejection in human transplants.
Topics: Adolescent; Adult; Aged; Cornea; Corneal Transplantation; Endothelium; Epithelium; Female; Glaucoma; | 1973 |
Systemic steroids and ocular fluid dynamics. I. Analysis of the sample as a whole. Influence of dosage and duration of therapy.
Topics: Adolescent; Adult; Aged; Aqueous Humor; Child; Drinking; Female; Humans; Intraocular Pressure; Male; | 1972 |
Cyclocryotherapy in advanced inadequately controlled glaucoma.
Topics: Adolescent; Adult; Aged; Atropine; Cryosurgery; Dexamethasone; Erythromycin; Female; Follow-Up Studi | 1973 |
Chronic open-angle glaucoma secondary to rhegmatogenous retinal detachment.
Topics: Acetazolamide; Adolescent; Adult; Betamethasone; Child; Cortisone; Electrocoagulation; Epinephrine; | 1973 |
New implant for drainage in glaucoma. Clinical trial.
Topics: Acrylates; Adolescent; Adult; Aged; Drainage; Female; Follow-Up Studies; Glaucoma; Humans; Intraocul | 1969 |
Herpetic keratouveitis. Clinical experiences.
Topics: Adult; Atropine; Corneal Transplantation; Corneal Ulcer; Female; Herpes Zoster Ophthalmicus; Humans; | 1971 |
Intercalary staphyloma in a case of herpes zoster ophthalmicus.
Topics: Aged; Atropine; Chloramphenicol; Eye Diseases; Herpes Zoster Ophthalmicus; Humans; Intraocular Press | 1967 |
Clinical investigations on the effect of glucocorticoids on intraocular tension.
Topics: Adolescent; Adult; Aged; Chorioretinitis; Humans; Intraocular Pressure; Middle Aged; Prednisolone; P | 1969 |
Peripheral uveitis in patients with multiple sclerosis.
Topics: Adolescent; Adult; Female; Glucocorticoids; Humans; Intraocular Pressure; Male; Methylprednisolone; | 1970 |
Report of a case of sphenoid fissure syndrome studied by orbital venography.
Topics: Adolescent; Blepharoptosis; Cavernous Sinus; Centrifugation, Density Gradient; Constriction; Female; | 1971 |
Posterior subcapsular cataract (P.S.C.) and systemic steroid therapy.
Topics: Adolescent; Adult; Aged; Cataract; Child; Child, Preschool; Collagen Diseases; Female; Glucocorticoi | 1968 |
[Clinical studies on the effects of glucocorticoids on the intrabulbar pressure].
Topics: Adolescent; Adult; Aged; Humans; Intraocular Pressure; Middle Aged; Prednisolone; Prednisone; Tonome | 1969 |
Effect of systemically administered corticosteroids on intraocular pressure and fluid dynamics.
Topics: Adult; Aqueous Humor; Female; Humans; Intraocular Pressure; Male; Middle Aged; Prednisone; Tonometry | 1965 |