prednisone has been researched along with Insulin Resistance in 56 studies
Prednisone: A synthetic anti-inflammatory glucocorticoid derived from CORTISONE. It is biologically inert and converted to PREDNISOLONE in the liver.
prednisone : A synthetic glucocorticoid drug that is particularly effective as an immunosuppressant, and affects virtually all of the immune system. Prednisone is a prodrug that is converted by the liver into prednisolone (a beta-hydroxy group instead of the oxo group at position 11), which is the active drug and also a steroid.
Insulin Resistance: Diminished effectiveness of INSULIN in lowering blood sugar levels: requiring the use of 200 units or more of insulin per day to prevent HYPERGLYCEMIA or KETOSIS.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Prednisone-induced insulin resistance may depend on either reduced sensitivity (receptor defect) or reduced response to insulin (postreceptor defect)." | 9.05 | An in vivo and in vitro study of the mechanism of prednisone-induced insulin resistance in healthy subjects. ( Bruno, A; Cassader, M; Cavallo-Perin, P; Dall'omo, AM; Imbimbo, B; Masciola, P; Ozzello, A; Pagano, G, 1983) |
| "Debate still exist about the safety of long-term use of prednisone (PD) versus hydrocortisone (HC) for treating children with congenital adrenal hyperplasia -21OH D (CAH)." | 9.01 | Long-term prednisone versus hydrocortisone treatment in children with classic Congenital Adrenal Hyperplasia (CAH) and a brief review of the literature. ( Abugabal, AMS; Ahmed, SEAM; De Sanctis, V; Elawwa, A; Emam, MHA; Ramadan, MA; Soliman, AT, 2019) |
| "Children who are prednisone-exposed in utero (low dose) have no increased risk for insulin resistance at the age of approximately 7 years." | 8.31 | Does prednisone use in pregnant women with rheumatoid arthritis induce insulin resistance in the offspring? ( de Steenwinkel, FDO; Dolhain, RJEM; Hazes, JMW; Hokken-Koelega, ACS, 2023) |
| ", insulin sensitivity (SI) and first-(phi1) and second-phase insulin secretion (phi2), are impaired in after orthotopic liver transplantation (OLT), they were assesssed in patients that had undergone OLT for cirrhosis (n = 10) with cyclosporin A and low-dose steroid therapy (5 mg prednisone per day) and were compared with those of healthy matched control subjects (n = 10)." | 7.71 | Impact of cyclosporine and low-dose steroid therapy on insulin sensitivity and beta-cell function in patients with long-term liver grafts. ( Allers, C; Cobelli, C; Encke, A; Hanisch, E; Konrad, T; Lakos, C; Markus, B; Toffolo, G; Usadel, KH; Vicini, P; Viehmann, K, 2001) |
| "To determine the role insulin resistance may play in the catabolic effect of high-dose prednisone therapy, healthy volunteers were studied on four occasions with the hormone-clamp technique at two insulin infusion rates." | 7.67 | Contribution of insulin resistance to catabolic effect of prednisone on leucine metabolism in humans. ( Haymond, MW; Horber, F; Rodriguez, N; Schwenk, WF; Zimmerman, T, 1989) |
| " This study aims to compare the impact on beta-cell function and insulin resistance of prednisone 40 mg between adults with newly diagnosed T2DM and healthy adults." | 5.34 | Effect of short-term prednisone on beta-cell function in subjects with type 2 diabetes mellitus and healthy subjects. ( Adel, MM; Fogelfeld, L; Guerra, Y; Shah, M; Tahsin, B, 2020) |
| " This study assessed whether treatment with the glucagon-like peptide receptor agonist (GLP-1 RA) exenatide (EXE) could prevent GC-induced glucose intolerance." | 5.15 | Glucagon-like peptide-1 receptor agonist treatment prevents glucocorticoid-induced glucose intolerance and islet-cell dysfunction in humans. ( Diamant, M; Linssen, MM; Ouwens, DM; van Genugten, RE; van Raalte, DH, 2011) |
| "The objective of this study was to quantify the effects of daily 10 or 25 mg prednisone administration for one week on insulin sensitivity by employing a two-step hyperinsulinemic euglycemic glucose clamp (Step 1: insulin infusion = 20 mU/m²/min; Step 2: insulin infusion = 80 mU/m²/min) in healthy, lean males." | 5.15 | Short-term metabolic effects of prednisone administration in healthy subjects. ( Heinemann, L; Herman, GA; Hompesch, M; Kauh, EA; Kelley, DE; Maridakis, V; McCarthy, J; Mixson, LA; Morrow, L; Ruddy, MK; Shankar, S, 2011) |
| "Prednisone-induced insulin resistance may depend on either reduced sensitivity (receptor defect) or reduced response to insulin (postreceptor defect)." | 5.05 | An in vivo and in vitro study of the mechanism of prednisone-induced insulin resistance in healthy subjects. ( Bruno, A; Cassader, M; Cavallo-Perin, P; Dall'omo, AM; Imbimbo, B; Masciola, P; Ozzello, A; Pagano, G, 1983) |
| "Debate still exist about the safety of long-term use of prednisone (PD) versus hydrocortisone (HC) for treating children with congenital adrenal hyperplasia -21OH D (CAH)." | 5.01 | Long-term prednisone versus hydrocortisone treatment in children with classic Congenital Adrenal Hyperplasia (CAH) and a brief review of the literature. ( Abugabal, AMS; Ahmed, SEAM; De Sanctis, V; Elawwa, A; Emam, MHA; Ramadan, MA; Soliman, AT, 2019) |
| "Children who are prednisone-exposed in utero (low dose) have no increased risk for insulin resistance at the age of approximately 7 years." | 4.31 | Does prednisone use in pregnant women with rheumatoid arthritis induce insulin resistance in the offspring? ( de Steenwinkel, FDO; Dolhain, RJEM; Hazes, JMW; Hokken-Koelega, ACS, 2023) |
| " The homeostasis model assessment of insulin sensitivity showed intermediate values for patients who underwent a simultaneous pancreas-kidney transplant and correlated with prednisone dosages (in those who underwent kidney transplant alone) and tacrolimus levels (in patients who underwent a simultaneous pancreas-kidney transplant)." | 3.76 | Family history of diabetes as a new determinant of insulin sensitivity and secretion in patients who have undergone a simultaneous pancreas-kidney transplant. ( Dib, SA; Gonzalez, AM; Linhares, MM; Melaragno, CS; Neves, MD; Pacheco-Silva, A; Rangel, EB; Sá, JR, 2010) |
| " The ability of emodin to inhibit prednisone- or dexamethasone-induced insulin resistance was investigated in C57BL/6J mice and its effect on metabolic abnormalities was observed in DIO mice." | 3.76 | Emodin, a natural product, selectively inhibits 11beta-hydroxysteroid dehydrogenase type 1 and ameliorates metabolic disorder in diet-induced obese mice. ( Chen, JH; Dou, W; Feng, Y; Huang, SL; Leng, Y; Shen, JH; Shen, Y; Zhang, S, 2010) |
| " The only significant correlation of leptin concentrations was with homocysteine concentrations but not disease activity, prednisone dose, lipids or insulin resistance." | 3.75 | Adipokines as novel biomarkers in paediatric systemic lupus erythematosus. ( Al, M; Bargman, J; Bradley, T; Ng, L; Silverman, E; Tyrrell, P, 2009) |
| ", insulin sensitivity (SI) and first-(phi1) and second-phase insulin secretion (phi2), are impaired in after orthotopic liver transplantation (OLT), they were assesssed in patients that had undergone OLT for cirrhosis (n = 10) with cyclosporin A and low-dose steroid therapy (5 mg prednisone per day) and were compared with those of healthy matched control subjects (n = 10)." | 3.71 | Impact of cyclosporine and low-dose steroid therapy on insulin sensitivity and beta-cell function in patients with long-term liver grafts. ( Allers, C; Cobelli, C; Encke, A; Hanisch, E; Konrad, T; Lakos, C; Markus, B; Toffolo, G; Usadel, KH; Vicini, P; Viehmann, K, 2001) |
| "To determine the role insulin resistance may play in the catabolic effect of high-dose prednisone therapy, healthy volunteers were studied on four occasions with the hormone-clamp technique at two insulin infusion rates." | 3.67 | Contribution of insulin resistance to catabolic effect of prednisone on leucine metabolism in humans. ( Haymond, MW; Horber, F; Rodriguez, N; Schwenk, WF; Zimmerman, T, 1989) |
| "Treatment with dapagliflozin was safe and there was no difference in risk of hypoglycaemia compared with placebo." | 2.87 | Dapagliflozin for prednisone-induced hyperglycaemia in acute exacerbation of chronic obstructive pulmonary disease. ( Brandjes, DPM; Gerards, MC; Gerdes, VEA; Hageman, IMG; Hoekstra, JBL; Kross, M; Patberg, KW; Potter van Loon, BJ; Snijders, D; Venema, GE; Vriesendorp, TM, 2018) |
| "Acromegaly is characterized by growth hormone (GH) and insulinlike growth factor-1 (IGF-1) hypersecretion, and GH and IGF-1 play important roles in regulating body composition and glucose homeostasis." | 1.46 | Body Composition and Ectopic Lipid Changes With Biochemical Control of Acromegaly. ( Bredella, MA; Dichtel, LE; Gerweck, AV; Miller, KK; Schorr, M; Swearingen, B; Woodmansee, WW; Young, BJ, 2017) |
| " Although daily glucocorticoid therapy has been shown to extend ambulatory function in DMD, less frequent dosing is often used because of side effect concerns." | 1.46 | Long-Term Outcome of Interdisciplinary Management of Patients with Duchenne Muscular Dystrophy Receiving Daily Glucocorticoid Treatment. ( Jefferies, JL; McMahon, MA; Rutter, MM; Rybalsky, I; Sawnani, H; Shellenbarger, KC; Tian, C; Wong, BL, 2017) |
| "Insulin sensitivity was determined using euglycemic hyperinsulinemic clamp (EHGC) before, during the first glucocorticoid infusion and after 2 months of treatment." | 1.35 | Glucocorticoid effect on insulin sensitivity: a time frame. ( Beleslin, B; Ciric, J; Drezgic, M; Penezic, Z; Savic, S; Stojkovic, M; Trbojevic, B; Zarkovic, M, 2008) |
| "We describe a patient with type 1 diabetes with recurrent diabetic ketoacidosis and severe insulin resistance." | 1.30 | Severe insulin resistance in a patient with type 1 diabetes and stiff-man syndrome treated with insulin lispro. ( Chait, A; D'Alessio, D; Davis, C; Eng, L; Hirsch, IB; Lernmark, A, 1998) |
| "We report a patient with systemic lupus erythematosus and severe insulin resistance due to insulin receptor antibodies." | 1.30 | Insulin receptor antibodies and insulin resistance. ( Magsino, CH; Spencer, J, 1999) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 23 (41.07) | 18.7374 |
| 1990's | 4 (7.14) | 18.2507 |
| 2000's | 14 (25.00) | 29.6817 |
| 2010's | 11 (19.64) | 24.3611 |
| 2020's | 4 (7.14) | 2.80 |
| Authors | Studies |
|---|---|
| Quevedo-Abeledo, JC | 1 |
| Hernández-Díaz, M | 1 |
| Sánchez-Pérez, H | 1 |
| Medina-Vega, L | 1 |
| González-Rivero, AF | 1 |
| Almeida-Santiago, C | 1 |
| de Armas-Rillo, L | 1 |
| González-Gay, MÁ | 1 |
| Ferraz-Amaro, I | 1 |
| de Steenwinkel, FDO | 1 |
| Dolhain, RJEM | 1 |
| Hazes, JMW | 1 |
| Hokken-Koelega, ACS | 1 |
| Ahmed, SEAM | 1 |
| Soliman, AT | 1 |
| Ramadan, MA | 1 |
| Elawwa, A | 1 |
| Abugabal, AMS | 1 |
| Emam, MHA | 1 |
| De Sanctis, V | 1 |
| Machado, MPR | 1 |
| Schavinski, AZ | 1 |
| Deluque, AL | 1 |
| Volpato, GT | 1 |
| Campos, KE | 1 |
| Shah, M | 1 |
| Adel, MM | 1 |
| Tahsin, B | 1 |
| Guerra, Y | 1 |
| Fogelfeld, L | 1 |
| Bredella, MA | 1 |
| Schorr, M | 1 |
| Dichtel, LE | 1 |
| Gerweck, AV | 1 |
| Young, BJ | 1 |
| Woodmansee, WW | 1 |
| Swearingen, B | 1 |
| Miller, KK | 1 |
| Gerards, MC | 1 |
| Venema, GE | 1 |
| Patberg, KW | 1 |
| Kross, M | 1 |
| Potter van Loon, BJ | 1 |
| Hageman, IMG | 1 |
| Snijders, D | 1 |
| Brandjes, DPM | 1 |
| Hoekstra, JBL | 1 |
| Vriesendorp, TM | 1 |
| Gerdes, VEA | 1 |
| Peng, K | 1 |
| Pan, Y | 1 |
| Li, J | 1 |
| Khan, Z | 1 |
| Fan, M | 1 |
| Yin, H | 1 |
| Tong, C | 1 |
| Zhao, Y | 1 |
| Liang, G | 1 |
| Zheng, C | 1 |
| Wong, BL | 1 |
| Rybalsky, I | 1 |
| Shellenbarger, KC | 1 |
| Tian, C | 1 |
| McMahon, MA | 1 |
| Rutter, MM | 1 |
| Sawnani, H | 1 |
| Jefferies, JL | 1 |
| Zelada, H | 1 |
| Gamarra, D | 1 |
| Arbañil, H | 1 |
| Manrique, H | 1 |
| Benedini, S | 1 |
| Ruffini, E | 1 |
| Terruzzi, I | 1 |
| Mancuso, M | 1 |
| Luzi, L | 1 |
| Al, M | 1 |
| Ng, L | 1 |
| Tyrrell, P | 1 |
| Bargman, J | 1 |
| Bradley, T | 1 |
| Silverman, E | 1 |
| Murray, SC | 1 |
| Gasser, A | 1 |
| Hess, RS | 1 |
| Rangel, EB | 1 |
| Melaragno, CS | 1 |
| Neves, MD | 1 |
| Dib, SA | 1 |
| Gonzalez, AM | 1 |
| Linhares, MM | 1 |
| Pacheco-Silva, A | 1 |
| Sá, JR | 1 |
| Feng, Y | 1 |
| Huang, SL | 1 |
| Dou, W | 1 |
| Zhang, S | 1 |
| Chen, JH | 1 |
| Shen, Y | 1 |
| Shen, JH | 1 |
| Leng, Y | 1 |
| van Raalte, DH | 1 |
| van Genugten, RE | 1 |
| Linssen, MM | 1 |
| Ouwens, DM | 1 |
| Diamant, M | 1 |
| Kauh, EA | 1 |
| Mixson, LA | 1 |
| Shankar, S | 1 |
| McCarthy, J | 1 |
| Maridakis, V | 1 |
| Morrow, L | 1 |
| Heinemann, L | 1 |
| Ruddy, MK | 1 |
| Herman, GA | 1 |
| Kelley, DE | 1 |
| Hompesch, M | 1 |
| Penesová, A | 1 |
| Rádiková, Z | 1 |
| Vlček, M | 1 |
| Kerlik, J | 1 |
| Lukáč, J | 1 |
| Rovenský, J | 1 |
| Imrich, R | 1 |
| Ducobu, J | 1 |
| Lemieux, I | 1 |
| Houde, I | 1 |
| Pascot, A | 1 |
| Lachance, JG | 1 |
| Noël, R | 1 |
| Radeau, T | 1 |
| Després, JP | 1 |
| Bergeron, J | 1 |
| Zenda, T | 1 |
| Murase, Y | 1 |
| Yoshida, I | 1 |
| Muramoto, H | 1 |
| Okada, T | 1 |
| Yagi, K | 1 |
| BURKART, F | 1 |
| HARTMANN, G | 1 |
| FANKHAUSER, S | 1 |
| KOLLER, F | 1 |
| PALUMBO, PJ | 1 |
| MOLNAR, GD | 1 |
| TAUXE, WN | 1 |
| MERIMEE, TJ | 1 |
| Bird, BR | 1 |
| Daly, PA | 1 |
| Tkaczyk, M | 1 |
| Czupryniak, A | 1 |
| Lukamowicz, J | 1 |
| Ksiazek, E | 1 |
| Półtorak-Krawczyk, A | 1 |
| Swiatkowska, E | 1 |
| Nowicki, M | 1 |
| Lee, LA | 1 |
| Hobbs, KF | 1 |
| Page, KA | 1 |
| Dejardin, S | 1 |
| Kahn, CR | 1 |
| Kulkarni, RN | 1 |
| Herold, KC | 1 |
| Inzucchi, SE | 1 |
| Zarkovic, M | 1 |
| Beleslin, B | 1 |
| Ciric, J | 1 |
| Penezic, Z | 1 |
| Stojkovic, M | 1 |
| Trbojevic, B | 1 |
| Drezgic, M | 1 |
| Savic, S | 1 |
| Michel, H | 1 |
| Canivet, B | 1 |
| Poustis-Delpont, C | 1 |
| Mariani, R | 1 |
| Freychet, P | 1 |
| Pagano, G | 2 |
| Cavallo-Perin, P | 2 |
| Cassader, M | 1 |
| Bruno, A | 2 |
| Ozzello, A | 1 |
| Masciola, P | 1 |
| Dall'omo, AM | 2 |
| Imbimbo, B | 2 |
| Lombardi, A | 1 |
| Ozello, A | 1 |
| Yasuda, K | 1 |
| Hines, E | 1 |
| Kitabchi, AE | 1 |
| Galloway, JA | 1 |
| Osei, K | 1 |
| Henry, M | 1 |
| Ferguson, R | 1 |
| Micić, D | 1 |
| Brkić, S | 1 |
| Kendereski, A | 1 |
| Popović, V | 1 |
| Zorić, S | 1 |
| Nikolić, JA | 1 |
| Igrutinović, L | 1 |
| Ivanoska, D | 1 |
| Manojlović, D | 1 |
| Micić, J | 1 |
| Hirsch, IB | 1 |
| D'Alessio, D | 1 |
| Eng, L | 1 |
| Davis, C | 1 |
| Lernmark, A | 1 |
| Chait, A | 1 |
| Magsino, CH | 1 |
| Spencer, J | 1 |
| Jannot-Lamotte, MF | 1 |
| Raccah, D | 1 |
| Konrad, T | 1 |
| Markus, B | 1 |
| Allers, C | 1 |
| Vicini, P | 1 |
| Toffolo, G | 1 |
| Lakos, C | 1 |
| Viehmann, K | 1 |
| Hanisch, E | 1 |
| Encke, A | 1 |
| Cobelli, C | 1 |
| Usadel, KH | 1 |
| Vondra, K | 1 |
| Nĕmcová, D | 1 |
| Stárka, L | 1 |
| Bílek, R | 1 |
| Bendlová, B | 1 |
| Hampl, R | 1 |
| Hill, M | 1 |
| Hoza, J | 1 |
| Kot'átková, A | 1 |
| Vrbíková, J | 1 |
| Zamrazil, V | 1 |
| Kansal, PC | 1 |
| Stroud, RM | 1 |
| Boshell, BR | 1 |
| Zimmerman, T | 1 |
| Horber, F | 1 |
| Rodriguez, N | 1 |
| Schwenk, WF | 1 |
| Haymond, MW | 1 |
| Sims, RE | 1 |
| Rushford, FE | 1 |
| Huston, DP | 1 |
| Cunningham, GR | 1 |
| Vesely, DL | 1 |
| Coleman, MJ | 1 |
| Kohler, PO | 1 |
| Jordan, RM | 1 |
| Stanley, S | 1 |
| Kantor, FS | 1 |
| Berkman, PM | 1 |
| Alavi, IA | 1 |
| Sharma, BK | 1 |
| Pillay, VK | 1 |
| Zarowitz, H | 1 |
| Ryan, WG | 1 |
| Schwartz, TB | 1 |
| Nibbe, AF | 1 |
| Faulk, WP | 2 |
| Tomsovic, EJ | 2 |
| Fudenberg, HH | 2 |
| Imura, H | 1 |
| Morimoto, M | 1 |
| Kuzuya, H | 1 |
| de Assis, LM | 1 |
| Nicolau, W | 1 |
| Salomon, JB | 1 |
| de Cintra, AB | 1 |
| Pieroni, RR | 1 |
| Schweitzer, PM | 1 |
| Shreiber, S | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Glucocorticoid Effects in Patients With DM Type 2[NCT03661684] | Early Phase 1 | 10 participants (Actual) | Interventional | 2016-06-03 | Completed | ||
| Prednisolone-induced Impairment of Glucose Metabolism and Beta-cell Dysfunction and the Protective Effects of Exenatide: a Single-center, Randomized, Double-blind, Placebo-controlled Crossover Study in Healthy Volunteers[NCT00744224] | 8 participants (Anticipated) | Interventional | 2009-02-28 | Completed | |||
| The Effect of Prednisone on Atherogenesis as Studied in the Macrophage Foam Cell Formation Model System.[NCT03367663] | Early Phase 1 | 10 participants (Actual) | Interventional | 2018-01-17 | Completed | ||
| Effect of Specific Diet and Circuit-based Exercise on Weight and/or Fat Loss[NCT02325804] | 60 participants (Actual) | Interventional | 2014-12-31 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
4 reviews available for prednisone and Insulin Resistance
| Article | Year |
|---|---|
Long-term prednisone versus hydrocortisone treatment in children with classic Congenital Adrenal Hyperplasia (CAH) and a brief review of the literature.
Topics: Adrenal Hyperplasia, Congenital; Blood Pressure; Body Mass Index; Carotid Intima-Media Thickness; Ch | 2019 |
[Metabolic modifications related to immunosuppressive drugs].
Topics: Anticholesteremic Agents; Cyclosporine; Diabetes Mellitus; Heart Transplantation; Humans; Hyperlipid | 2002 |
When the patient is resistant or allergic to insulin.
Topics: Diabetes Mellitus; Drug Hypersensitivity; Humans; Insulin; Insulin Antibodies; Insulin Resistance; P | 1980 |
[Management of diabetes during corticosteroid therapy].
Topics: Adult; Blood Glucose; Diabetes Mellitus; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Doubl | 2000 |
7 trials available for prednisone and Insulin Resistance
| Article | Year |
|---|---|
Effect of short-term prednisone on beta-cell function in subjects with type 2 diabetes mellitus and healthy subjects.
Topics: Adult; Blood Glucose; C-Peptide; Case-Control Studies; Diabetes Mellitus, Type 2; Female; Humans; In | 2020 |
Dapagliflozin for prednisone-induced hyperglycaemia in acute exacerbation of chronic obstructive pulmonary disease.
Topics: Aged; Benzhydryl Compounds; Combined Modality Therapy; Diabetes Mellitus, Type 2; Double-Blind Metho | 2018 |
Glucagon-like peptide-1 receptor agonist treatment prevents glucocorticoid-induced glucose intolerance and islet-cell dysfunction in humans.
Topics: Adolescent; Adult; Blood Glucose; C-Peptide; Cross-Over Studies; Exenatide; Glucagon-Like Peptide 1; | 2011 |
Short-term metabolic effects of prednisone administration in healthy subjects.
Topics: Adolescent; Adult; Blood Glucose; Double-Blind Method; Glucocorticoids; Glucose Clamp Technique; Hum | 2011 |
Effects of prednisone withdrawal on the new metabolic triad in cyclosporine-treated kidney transplant patients.
Topics: Anti-Inflammatory Agents; Apolipoproteins B; Cardiovascular Diseases; Cholesterol, HDL; Cholesterol, | 2002 |
[Insulinsensitivity and beta-cell function in children with idiopathic nephrotic syndrome].
Topics: Adolescent; Blood Glucose; Child; Child, Preschool; Female; Glucocorticoids; Humans; Insulin; Insuli | 2006 |
An in vivo and in vitro study of the mechanism of prednisone-induced insulin resistance in healthy subjects.
Topics: 3-O-Methylglucose; Adipose Tissue; Adult; Blood Glucose; Female; Glucose; Humans; Insulin; Insulin R | 1983 |
45 other studies available for prednisone and Insulin Resistance
| Article | Year |
|---|---|
Amylin serum levels are upregulated in patients with systemic lupus erythematosus.
Topics: Case-Control Studies; Female; Humans; Insulin; Insulin Resistance; Islet Amyloid Polypeptide; Lupus | 2022 |
Does prednisone use in pregnant women with rheumatoid arthritis induce insulin resistance in the offspring?
Topics: Adiponectin; Arthritis, Rheumatoid; Birth Weight; Child; Female; Glucocorticoids; Humans; Insulin; I | 2023 |
The Treatment of Prednisone in Mild Diabetic Rats: Biochemical Parameters and Cell Response.
Topics: Animals; Blood Glucose; Body Weight; Diabetes Mellitus, Experimental; Glucocorticoids; Glucose Intol | 2020 |
Body Composition and Ectopic Lipid Changes With Biochemical Control of Acromegaly.
Topics: Acromegaly; Adipose Tissue; Adult; Aged; Blood Glucose; Body Composition; Cabergoline; Case-Control | 2017 |
11β-Hydroxysteroid Dehydrogenase Type 1(11β-HSD1) mediates insulin resistance through JNK activation in adipocytes.
Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 1; 3T3-L1 Cells; Adipocytes; Animals; Enzyme Activation; I | 2016 |
Long-Term Outcome of Interdisciplinary Management of Patients with Duchenne Muscular Dystrophy Receiving Daily Glucocorticoid Treatment.
Topics: Adolescent; Age Factors; Child; Cohort Studies; Dose-Response Relationship, Drug; Drug Administratio | 2017 |
Type B Insulin Resistance in Peru.
Topics: Adult; Autoantibodies; Autoimmune Diseases; Cyclophosphamide; Drug Therapy, Combination; Female; Hum | 2017 |
Glucose and leucine metabolism in lung tranplanted patients on low dose of steroids for immunosuppressive therapy.
Topics: Adult; Aged; Azathioprine; Blood Glucose; Cyclosporine; Fatty Acids, Nonesterified; Female; Glucocor | 2008 |
Adipokines as novel biomarkers in paediatric systemic lupus erythematosus.
Topics: Adipokines; Adiponectin; Adolescent; Biomarkers; Child; Child, Preschool; Cohort Studies; Dose-Respo | 2009 |
Transient hyperglycaemia in a prediabetic dog treated with prednisone and cyclosporin A.
Topics: Animals; Cyclosporine; Dog Diseases; Dogs; Hyperglycemia; Hypoglycemic Agents; Insulin; Insulin Resi | 2009 |
Family history of diabetes as a new determinant of insulin sensitivity and secretion in patients who have undergone a simultaneous pancreas-kidney transplant.
Topics: Adult; Blood Glucose; Body Mass Index; C-Peptide; Case-Control Studies; Diabetes Mellitus; Female; H | 2010 |
Emodin, a natural product, selectively inhibits 11beta-hydroxysteroid dehydrogenase type 1 and ameliorates metabolic disorder in diet-induced obese mice.
Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 1; Adrenal Cortex Hormones; Animals; Cell Line; Dexamethas | 2010 |
Chronic inflammation and low-dose glucocorticoid effects on glucose metabolism in premenopausal females with rheumatoid arthritis free of conventional metabolic risk factors.
Topics: Adult; Analysis of Variance; Arthritis, Rheumatoid; Biomarkers; Blood Glucose; C-Reactive Protein; C | 2013 |
Does the use of insulin in a patient with liver dysfunction increase water retention in the body, i.e. cause insulin oedema?
Topics: Aged; Anti-Inflammatory Agents; Diabetes Mellitus, Type 2; Edema; Female; Hepatitis, Autoimmune; Hum | 2003 |
[INSULIN RESISTANCE AND INSULIN ALLERGY].
Topics: Drug Hypersensitivity; Globins; Humans; Insulin; Insulin Antibodies; Insulin Resistance; Insulin, Lo | 1963 |
ADRENAL STEROID THERAPY IN INSULIN RESISTANCE: A CLINICAL AND IMMUNOLOGIC STUDY.
Topics: Dexamethasone; Humans; Insulin Antibodies; Insulin Resistance; Prednisone; Thyroid Function Tests | 1964 |
INSULIN RESISTANCE; STUDY OF EFFECT OF 6-MERCAPTOPURINE.
Topics: Diabetes Mellitus; Humans; Insulin; Insulin Resistance; Mercaptopurine; Metabolism; Pharmacology; Pr | 1965 |
Uncommon hematologic malignancies. Case 3. Parotid swelling during treatment for transformed mycosis fungoides.
Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cell Transformation, Neoplastic; Cyclopho | 2003 |
Lipodystrophy and metabolic abnormalities in a case of adult dermatomyositis.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Dermatomyositis; Drug Therapy, Combination; Female; Glucoco | 2007 |
A patient with type B insulin resistance syndrome, responsive to immune therapy.
Topics: Autoantibodies; Blood Glucose; Combined Modality Therapy; Creatinine; Diabetes Mellitus, Type 2; Dia | 2007 |
Glucocorticoid effect on insulin sensitivity: a time frame.
Topics: Adult; Glucocorticoids; Glucose Clamp Technique; Graves Ophthalmopathy; Humans; Hyperinsulinism; Ins | 2008 |
[Therapy of diabetes mellitus in the course of resistance to insulin or allergy to insulin].
Topics: Diabetes Mellitus; Dimercaprol; Drug Hypersensitivity; Humans; Insulin; Insulin Resistance; Mechlore | 1967 |
Prednisone increases the number of insulin receptors in erythrocytes from children.
Topics: Binding Sites; Blood Glucose; Child; Child, Preschool; Erythrocytes; Female; Humans; Infant; Insulin | 1983 |
Deflazacort versus prednisone diabetogenic effect evaluated by glucose clamp and compartmental analysis.
Topics: Adult; Blood Glucose; Humans; Insulin; Insulin Resistance; Insulin Secretion; Kinetics; Male; Predni | 1984 |
Hypercortisolism and insulin resistance: comparative effects of prednisone, hydrocortisone, and dexamethasone on insulin binding of human erythrocytes.
Topics: Adult; Dexamethasone; Erythrocytes; Female; Glucocorticoids; Glucose Tolerance Test; Humans; Hydroco | 1982 |
Differential effects of systemic insulin delivery and prednisone on tissue glucose and insulin sensitivity in insulin-dependent diabetes mellitus pancreas recipients.
Topics: Adult; Azathioprine; Blood Glucose; Cyclosporine; Diabetes Mellitus, Type 1; Diabetic Nephropathies; | 1994 |
Immunological resistance to human biosynthetic insulin--effects of immunosuppression and plasmapheresis.
Topics: Azathioprine; Diabetes Mellitus, Type 1; Humans; Immunosuppressive Agents; Insulin; Insulin Antibodi | 1993 |
Severe insulin resistance in a patient with type 1 diabetes and stiff-man syndrome treated with insulin lispro.
Topics: Adult; Blood Glucose; Body Mass Index; Diabetes Mellitus, Type 1; Diabetic Ketoacidosis; Female; Glu | 1998 |
Insulin receptor antibodies and insulin resistance.
Topics: Acanthosis Nigricans; Adult; Anti-Inflammatory Agents; Autoantibodies; Blood Glucose; Female; Humans | 1999 |
Impact of cyclosporine and low-dose steroid therapy on insulin sensitivity and beta-cell function in patients with long-term liver grafts.
Topics: Adult; Blood Glucose; C-Peptide; Case-Control Studies; Cyclosporine; Female; Glucocorticoids; Glucos | 2001 |
[Metformin has a positive effect on disorders of carbohydrate metabolism in long-term care with low doses of prednisone].
Topics: Adolescent; Adult; Female; Glucocorticoids; Glucose Intolerance; Glucose Tolerance Test; Humans; Hyp | 2002 |
Free and total insulin levels in a patient with insulin-resistant diabetes mellitus and chronic lymphatic leukemia: effect of prednisone therapy.
Topics: Adolescent; Adult; Aged; Diabetes Complications; Diabetes Mellitus; Humans; Insulin; Insulin Antibod | 1976 |
Contribution of insulin resistance to catabolic effect of prednisone on leucine metabolism in humans.
Topics: Adult; Basal Metabolism; Glucagon; Glucose; Growth Hormone; Humans; Insulin; Insulin Infusion System | 1989 |
Successful immunosuppressive therapy in a patient with autoantibodies to insulin receptors and immune complex glomerulonephritis.
Topics: Adult; Antigen-Antibody Complex; Autoantibodies; Blood Glucose; Cyclophosphamide; Drug Therapy, Comb | 1987 |
Hyperalimentation as cause of markedly worsened metabolic control in a patient with autoantibodies to the insulin receptor.
Topics: Acanthosis Nigricans; Adult; Autoantibodies; Blood Glucose; Cyclophosphamide; Female; Humans; Hyperg | 1985 |
Steroid amelioration of immunogenic insulin-resistant diabetes: a proposed mechanism.
Topics: Aged; Autoradiography; Diabetes Mellitus; Electrophoresis; Female; gamma-Globulins; Humans; Immunoel | 1967 |
Steroid-induced diabetic ketoacidosis.
Topics: Acetone; Adolescent; Adrenocorticotropic Hormone; Adult; Diabetic Ketoacidosis; Female; Glycosuria; | 1971 |
Postpancreatectomy insulin-resistant diabetes mellitus. Improvement after prednisone and 5-fluorouracil.
Topics: Diabetes Mellitus; Female; Fluorouracil; Humans; Insulin Resistance; Middle Aged; Pancreatectomy; Pa | 1972 |
Serum immunoreactive insulin levels during glucose tolerance and intensive islet stimulation. Effect of prednisone.
Topics: Adolescent; Adult; Body Weight; Diabetes Mellitus; Female; Glucose Tolerance Test; Humans; Hyperglyc | 1971 |
Insulin resistance in juvenile diabetes mellitus. Immunologic studies.
Topics: Anemia, Hemolytic, Autoimmune; Antibodies, Anti-Idiotypic; Antigens; Bone Marrow Examination; Child; | 1970 |
Anaphylaxis and red cell survival studies in a child with insulin-resistant diabetes mellitus.
Topics: Animals; Autoradiography; Cell Survival; Child; Chromatography, Ion Exchange; Chromium Isotopes; Com | 1971 |
[Insulin resistant diabetes].
Topics: Diabetes Mellitus; Humans; Immunosuppressive Agents; Insulin; Insulin Antibodies; Insulin Resistance | 1971 |
Immunobiological studies in two cases of insulin-resistant diabetes.
Topics: Adult; Chlorpropamide; Diabetes Insipidus; Diabetes Mellitus; Female; Humans; Insulin; Insulin Antib | 1970 |
[Clinical aspects of insulin resistance].
Topics: Animals; Guinea Pigs; Hemagglutination Tests; Humans; Hypoglycemic Agents; Insulin Antibodies; Insul | 1969 |
[A case of insulin-resistant diabetes mellitus].
Topics: Diabetes Mellitus; Drug Tolerance; Hepatitis B; Humans; Insulin; Insulin Resistance; Middle Aged; Pr | 1965 |