prednisone has been researched along with Hyperuricemia in 13 studies
Prednisone: A synthetic anti-inflammatory glucocorticoid derived from CORTISONE. It is biologically inert and converted to PREDNISOLONE in the liver.
prednisone : A synthetic glucocorticoid drug that is particularly effective as an immunosuppressant, and affects virtually all of the immune system. Prednisone is a prodrug that is converted by the liver into prednisolone (a beta-hydroxy group instead of the oxo group at position 11), which is the active drug and also a steroid.
Hyperuricemia: Excessive URIC ACID or urate in blood as defined by its solubility in plasma at 37 degrees C; greater than 0.42mmol per liter (7.0mg/dL) in men or 0.36mmol per liter (6.0mg/dL) in women. This condition is caused by overproduction of uric acid or impaired renal clearance. Hyperuricemia can be acquired, drug-induced or genetically determined (LESCH-NYHAN SYNDROME). It is associated with HYPERTENSION and GOUT.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Thirty-four symptomatic CHF participants with hyperuricemia (≥ 565 μmol/L) were randomized to receive prednisone (1 mg/kg/d, orally) or allopurinol (100 mg, thrice daily, orally) for 4 weeks." | 9.17 | Prednisone in Uric Acid lowering in Symptomatic Heart Failure Patients With Hyperuricemia (PUSH-PATH) study. ( Gao, Y; Ji, L; Ji, Z; Liu, C; Liu, G; Liu, K; Tian, L; Wang, L; Zhao, Q; Zhen, Y, 2013) |
| "Prednisone therapy was administered for a short time to 191 symptomatic HF patients with hyperuricemia (serum uric acid > 7 mg/dl)." | 7.81 | Prednisone in Uric Acid Lowering in Symptomatic Heart Failure Patients with Hyperuricemia -- The PUSH-PATH3 Study. ( Duan, L; Ji, L; Li, L; Liu, C; Liu, G; Liu, K; Ma, G; Meng, H; Tian, L; Wang, L; Zhai, J; Zhao, Q; Zhen, Y; Zheng, M, 2015) |
| "Thirty-four symptomatic CHF participants with hyperuricemia (≥ 565 μmol/L) were randomized to receive prednisone (1 mg/kg/d, orally) or allopurinol (100 mg, thrice daily, orally) for 4 weeks." | 5.17 | Prednisone in Uric Acid lowering in Symptomatic Heart Failure Patients With Hyperuricemia (PUSH-PATH) study. ( Gao, Y; Ji, L; Ji, Z; Liu, C; Liu, G; Liu, K; Tian, L; Wang, L; Zhao, Q; Zhen, Y, 2013) |
| " Those treated with tacrolimus had lower, not significant, prevalence of hypertension, hyperuricemia, hypoalbuminemia, hypercholesterolemia, hypertriglyceridemia, and low serum HDL-cholesterol than those treated with sirolimus and cyclosporine." | 3.83 | Effect of Immunosuppressive Therapy on Cardiovascular Risk Factor Prevalence in Kidney-Transplanted Children: Comparative Study. ( Camarena-Arias, PA; García-Bello, JA; Mendoza-Gómez, E; Romo-Del Río, EG; Santos-Caballero, M, 2016) |
| "Prednisone therapy was administered for a short time to 191 symptomatic HF patients with hyperuricemia (serum uric acid > 7 mg/dl)." | 3.81 | Prednisone in Uric Acid Lowering in Symptomatic Heart Failure Patients with Hyperuricemia -- The PUSH-PATH3 Study. ( Duan, L; Ji, L; Li, L; Liu, C; Liu, G; Liu, K; Ma, G; Meng, H; Tian, L; Wang, L; Zhai, J; Zhao, Q; Zhen, Y; Zheng, M, 2015) |
| "Eight patients had Burkitt lymphoma and three had Burkitt leukemia; their median age was 48 years." | 1.35 | Efficacy of continuous venovenous hemofiltration with chemotherapy in patients with Burkitt lymphoma and leukemia at high risk of tumor lysis syndrome. ( Choi, KA; Huh, W; Kim, DJ; Kim, K; Kim, WS; Kim, YG; Ko, YH; Lee, JE; Oh, HY, 2009) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (15.38) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (23.08) | 29.6817 |
| 2010's | 8 (61.54) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| de Denus, S | 1 |
| Rouleau, JL | 1 |
| Kannangara, DR | 1 |
| Graham, GG | 1 |
| Williams, KM | 1 |
| Day, RO | 2 |
| Liu, C | 3 |
| Liu, K | 3 |
| Galardy, PJ | 1 |
| Hochberg, J | 1 |
| Perkins, SL | 1 |
| Harrison, L | 1 |
| Goldman, S | 1 |
| Cairo, MS | 1 |
| Meng, H | 1 |
| Liu, G | 2 |
| Zhai, J | 1 |
| Zhen, Y | 2 |
| Zhao, Q | 2 |
| Zheng, M | 1 |
| Ma, G | 1 |
| Wang, L | 2 |
| Tian, L | 2 |
| Ji, L | 2 |
| Duan, L | 1 |
| Li, L | 1 |
| García-Bello, JA | 1 |
| Romo-Del Río, EG | 1 |
| Mendoza-Gómez, E | 1 |
| Camarena-Arias, PA | 1 |
| Santos-Caballero, M | 1 |
| Fontenot, A | 1 |
| Harris, P | 1 |
| Macasa, A | 1 |
| Menon, Y | 1 |
| Quinet, R | 1 |
| Choi, KA | 1 |
| Lee, JE | 1 |
| Kim, YG | 1 |
| Kim, DJ | 1 |
| Kim, K | 1 |
| Ko, YH | 1 |
| Oh, HY | 1 |
| Kim, WS | 1 |
| Huh, W | 1 |
| Terkeltaub, R | 1 |
| Zelman, D | 1 |
| Scavulli, J | 1 |
| Perez-Ruiz, F | 1 |
| Lioté, F | 1 |
| Gao, Y | 1 |
| Ji, Z | 1 |
| SCOTT, JT | 1 |
| DIXON, AS | 1 |
| BYWATERS, EG | 1 |
| ALPERIN, JB | 1 |
| LEVIN, WC | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Prednisone Versus Allopurinol for Symptomatic Heart Failure Patients With Hyperuricemia[NCT00919243] | Phase 4 | 40 participants (Anticipated) | Interventional | 2009-02-28 | Completed | ||
| Long-term Prednisone Use in Patients With Advanced Heart Failure (ACCF/AHA Stage D) and Hyperuricemia[NCT02282683] | Phase 2/Phase 3 | 90 participants (Anticipated) | Interventional | 2013-12-31 | Recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 trials available for prednisone and Hyperuricemia
| Article | Year |
|---|---|
Rasburicase in the prevention of laboratory/clinical tumour lysis syndrome in children with advanced mature B-NHL: a Children's Oncology Group Report.
Topics: Acute Kidney Injury; Adolescent; Antibodies, Monoclonal, Murine-Derived; Antineoplastic Combined Che | 2013 |
Prednisone in Uric Acid lowering in Symptomatic Heart Failure Patients With Hyperuricemia (PUSH-PATH) study.
Topics: Adult; Allopurinol; Creatinine; Dyspnea; Female; Glomerular Filtration Rate; Glucocorticoids; Gout S | 2013 |
Prednisone in Uric Acid lowering in Symptomatic Heart Failure Patients With Hyperuricemia (PUSH-PATH) study.
Topics: Adult; Allopurinol; Creatinine; Dyspnea; Female; Glomerular Filtration Rate; Glucocorticoids; Gout S | 2013 |
Prednisone in Uric Acid lowering in Symptomatic Heart Failure Patients With Hyperuricemia (PUSH-PATH) study.
Topics: Adult; Allopurinol; Creatinine; Dyspnea; Female; Glomerular Filtration Rate; Glucocorticoids; Gout S | 2013 |
Prednisone in Uric Acid lowering in Symptomatic Heart Failure Patients With Hyperuricemia (PUSH-PATH) study.
Topics: Adult; Allopurinol; Creatinine; Dyspnea; Female; Glomerular Filtration Rate; Glucocorticoids; Gout S | 2013 |
11 other studies available for prednisone and Hyperuricemia
| Article | Year |
|---|---|
High-dose prednisone in patients with heart failure and hyperuricemia: friend and foe?
Topics: Allopurinol; Female; Glucocorticoids; Gout Suppressants; Heart Failure; Humans; Hyperuricemia; Male; | 2013 |
Hypouricemic effects of prednisone and allopurinol: an uneven playing field?
Topics: Allopurinol; Female; Glucocorticoids; Gout Suppressants; Heart Failure; Humans; Hyperuricemia; Male; | 2014 |
Reply to Day et al.--hypouricemic effect of prednisone in heart failure: possible mechanisms.
Topics: Allopurinol; Female; Glucocorticoids; Gout Suppressants; Heart Failure; Humans; Hyperuricemia; Male; | 2014 |
Prednisone in Uric Acid Lowering in Symptomatic Heart Failure Patients with Hyperuricemia -- The PUSH-PATH3 Study.
Topics: Adult; Aged; Creatinine; Female; Gout Suppressants; Heart Failure; Humans; Hyperuricemia; Male; Midd | 2015 |
Prednisone for cardiac failure in patients with hypertension.
Topics: Female; Gout Suppressants; Heart Failure; Humans; Hyperuricemia; Male; Prednisone | 2015 |
Effect of Immunosuppressive Therapy on Cardiovascular Risk Factor Prevalence in Kidney-Transplanted Children: Comparative Study.
Topics: Adolescent; Adult; Cardiovascular Diseases; Child; Cyclosporine; Female; Humans; Hypertension; Hyper | 2016 |
An initial presentation of polyarticular gout with spinal involvement.
Topics: Aged, 80 and over; Allopurinol; Anti-Inflammatory Agents; Diffusion Magnetic Resonance Imaging; Fema | 2008 |
Efficacy of continuous venovenous hemofiltration with chemotherapy in patients with Burkitt lymphoma and leukemia at high risk of tumor lysis syndrome.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Burkitt Lymphoma; Cyclophosphamide; Cytarabin | 2009 |
Gout Study Group: update on hyperuricemia and gout.
Topics: Acute Disease; Anti-Inflammatory Agents, Non-Steroidal; Colchicine; Diet; Europe; Febuxostat; Gout; | 2009 |
ASSOCIATION OF HYPERURICAEMIA AND GOUT WITH HYPERPARATHYROIDISM.
Topics: Adenoma; Blood Chemical Analysis; Diagnosis; Gout; Humans; Hyperparathyroidism; Hyperuricemia; Nephr | 1964 |
EXTREME HYPERURICEMIA ASSOCIATED WITH PREDNISONE THERAPY FOR ACUTE LYMPHOBLASTIC LEUKEMIA.
Topics: Adolescent; Blood; Blood Urea Nitrogen; Humans; Hyperuricemia; Leukemia; Leukemia, Lymphoid; Lymphoc | 1964 |