Page last updated: 2024-11-07

prednisone and Hyperinsulinism

prednisone has been researched along with Hyperinsulinism in 13 studies

Prednisone: A synthetic anti-inflammatory glucocorticoid derived from CORTISONE. It is biologically inert and converted to PREDNISOLONE in the liver.
prednisone : A synthetic glucocorticoid drug that is particularly effective as an immunosuppressant, and affects virtually all of the immune system. Prednisone is a prodrug that is converted by the liver into prednisolone (a beta-hydroxy group instead of the oxo group at position 11), which is the active drug and also a steroid.

Hyperinsulinism: A syndrome with excessively high INSULIN levels in the BLOOD. It may cause HYPOGLYCEMIA. Etiology of hyperinsulinism varies, including hypersecretion of a beta cell tumor (INSULINOMA); autoantibodies against insulin (INSULIN ANTIBODIES); defective insulin receptor (INSULIN RESISTANCE); or overuse of exogenous insulin or HYPOGLYCEMIC AGENTS.

Research Excerpts

ExcerptRelevanceReference
" This study assessed whether treatment with the glucagon-like peptide receptor agonist (GLP-1 RA) exenatide (EXE) could prevent GC-induced glucose intolerance."5.15Glucagon-like peptide-1 receptor agonist treatment prevents glucocorticoid-induced glucose intolerance and islet-cell dysfunction in humans. ( Diamant, M; Linssen, MM; Ouwens, DM; van Genugten, RE; van Raalte, DH, 2011)
"Insulin sensitivity was determined using euglycemic hyperinsulinemic clamp (EHGC) before, during the first glucocorticoid infusion and after 2 months of treatment."1.35Glucocorticoid effect on insulin sensitivity: a time frame. ( Beleslin, B; Ciric, J; Drezgic, M; Penezic, Z; Savic, S; Stojkovic, M; Trbojevic, B; Zarkovic, M, 2008)
"Hyperlipidemia was observed between the 4th month and the end of the first year after transplantation in 83% of the patients."1.26Hyperlipidemias in patients with kidney transplants. ( Brunner, F; Harder, F; Kobza, K; Stähelin, HB; Thiel, G, 1976)

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19907 (53.85)18.7374
1990's1 (7.69)18.2507
2000's4 (30.77)29.6817
2010's1 (7.69)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
van Raalte, DH1
van Genugten, RE1
Linssen, MM1
Ouwens, DM1
Diamant, M1
Semiz, S1
Bircan, I1
Akçurin, S1
Mihçi, E1
Melikoglu, M1
Karagüzel, G1
Kiliçaslan, B1
Karpuzoğlu, G1
Zenda, T1
Murase, Y1
Yoshida, I1
Muramoto, H1
Okada, T1
Yagi, K1
ALAJOUANINE, T1
NEHLIL, J1
CONTAMIN, F1
CATHALA, HP1
Dessein, PH1
Joffe, BI1
Stanwix, AE1
Christian, BF1
Veller, M1
Zarkovic, M1
Beleslin, B1
Ciric, J1
Penezic, Z1
Stojkovic, M1
Trbojevic, B1
Drezgic, M1
Savic, S1
Kailin, X1
Yushu, H1
Qingchao, W1
Yuanbo, L1
Stähelin, HB1
Kobza, K1
Brunner, F1
Harder, F1
Thiel, G1
Shames, JM1
Dhurandhar, NR1
Blackard, WG1
Fischer, HU1
Schütze, I1
Bannert, N1
Wüstenberg, PW1
O'Brien, D1
Creutzfeldt, W1
Frerichs, H1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Prednisolone-induced Impairment of Glucose Metabolism and Beta-cell Dysfunction and the Protective Effects of Exenatide: a Single-center, Randomized, Double-blind, Placebo-controlled Crossover Study in Healthy Volunteers[NCT00744224]8 participants (Anticipated)Interventional2009-02-28Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for prednisone and Hyperinsulinism

ArticleYear
[The hypoglycemia syndrome].
    Zeitschrift fur die gesamte innere Medizin und ihre Grenzgebiete, 1970, Jun-01, Volume: 25, Issue:11

    Topics: Alloxan; Angiography; Antibiotics, Antineoplastic; Blood Glucose; Diagnosis, Differential; Diazoxide

1970

Trials

1 trial available for prednisone and Hyperinsulinism

ArticleYear
Glucagon-like peptide-1 receptor agonist treatment prevents glucocorticoid-induced glucose intolerance and islet-cell dysfunction in humans.
    Diabetes care, 2011, Volume: 34, Issue:2

    Topics: Adolescent; Adult; Blood Glucose; C-Peptide; Cross-Over Studies; Exenatide; Glucagon-Like Peptide 1;

2011

Other Studies

11 other studies available for prednisone and Hyperinsulinism

ArticleYear
Persistent hyperinsulinaemic hypoglycaemia of infancy: case report.
    East African medical journal, 2002, Volume: 79, Issue:10

    Topics: Anti-Inflammatory Agents; Blood Glucose; Consanguinity; Diazoxide; Epilepsy; Glucagon; Humans; Hyper

2002
Does the use of insulin in a patient with liver dysfunction increase water retention in the body, i.e. cause insulin oedema?
    European journal of gastroenterology & hepatology, 2003, Volume: 15, Issue:5

    Topics: Aged; Anti-Inflammatory Agents; Diabetes Mellitus, Type 2; Edema; Female; Hepatitis, Autoimmune; Hum

2003
[Hypoglycemic brain disease caused by probable islet adenoma; disappearance of the disorders under the effect of corticotherapy].
    Revue neurologique, 1959, Volume: 100, Issue:1

    Topics: Adenoma; Brain; Brain Diseases; Hyperinsulinism; Hypoglycemic Agents; Islets of Langerhans; Neoplasm

1959
Glucocorticoids and insulin sensitivity in rheumatoid arthritis.
    The Journal of rheumatology, 2004, Volume: 31, Issue:5

    Topics: Arthritis, Rheumatoid; Cardiovascular Diseases; Female; Glucocorticoids; Humans; Hyperinsulinism; Ma

2004
Glucocorticoid effect on insulin sensitivity: a time frame.
    Journal of endocrinological investigation, 2008, Volume: 31, Issue:3

    Topics: Adult; Glucocorticoids; Glucose Clamp Technique; Graves Ophthalmopathy; Humans; Hyperinsulinism; Ins

2008
Hyperinsulinemia accompanying hyperglycemia in Chinese patients with aplastic anemia.
    American journal of hematology, 1997, Volume: 56, Issue:3

    Topics: Adolescent; Adult; Aged; Anabolic Agents; Anemia, Aplastic; Blood Glucose; Female; Glucagon; Glucoco

1997
Hyperlipidemias in patients with kidney transplants.
    Klinische Wochenschrift, 1976, Sep-15, Volume: 54, Issue:18

    Topics: Age Factors; Body Weight; Follow-Up Studies; Glomerular Filtration Rate; Humans; Hyperinsulinism; Hy

1976
Insulin-secreting bronchial carcinoid tumor with widespread metastases.
    The American journal of medicine, 1968, Volume: 44, Issue:4

    Topics: Adult; Blood Glucose; Bronchi; Bronchial Neoplasms; Carcinoma, Adenoid Cystic; Diazoxide; Female; Gl

1968
[Childhood hypoglycemia with convulsions].
    Zeitschrift fur arztliche Fortbildung, 1974, Volume: 68, Issue:1

    Topics: Blood Glucose; Child, Preschool; Electroencephalography; Epinephrine; Fasting; Female; Glucagon; Hum

1974
Management of hypoglycemia.
    The Journal of the Florida Medical Association, 1971, Volume: 58, Issue:5

    Topics: Blood Glucose; Child; Dietary Carbohydrates; Ephedrine; Glucose; Humans; Hyperinsulinism; Hypoglycem

1971
[Hypoglycemia factitia. A differential diagnostic significant form of hyperinsulinism].
    Deutsche medizinische Wochenschrift (1946), 1969, Apr-18, Volume: 94, Issue:16

    Topics: Adolescent; Diabetes Mellitus, Type 1; Diabetic Coma; Diagnosis, Differential; Female; Humans; Hyper

1969
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