prednisone and Hyperinsulinism
prednisone has been researched along with Hyperinsulinism in 13 studies
Prednisone: A synthetic anti-inflammatory glucocorticoid derived from CORTISONE. It is biologically inert and converted to PREDNISOLONE in the liver.
prednisone : A synthetic glucocorticoid drug that is particularly effective as an immunosuppressant, and affects virtually all of the immune system. Prednisone is a prodrug that is converted by the liver into prednisolone (a beta-hydroxy group instead of the oxo group at position 11), which is the active drug and also a steroid.
Hyperinsulinism: A syndrome with excessively high INSULIN levels in the BLOOD. It may cause HYPOGLYCEMIA. Etiology of hyperinsulinism varies, including hypersecretion of a beta cell tumor (INSULINOMA); autoantibodies against insulin (INSULIN ANTIBODIES); defective insulin receptor (INSULIN RESISTANCE); or overuse of exogenous insulin or HYPOGLYCEMIC AGENTS.
Research Excerpts
Excerpt | Relevance | Reference |
---|---|---|
" This study assessed whether treatment with the glucagon-like peptide receptor agonist (GLP-1 RA) exenatide (EXE) could prevent GC-induced glucose intolerance." | 5.15 | Glucagon-like peptide-1 receptor agonist treatment prevents glucocorticoid-induced glucose intolerance and islet-cell dysfunction in humans. ( Diamant, M; Linssen, MM; Ouwens, DM; van Genugten, RE; van Raalte, DH, 2011) |
"Insulin sensitivity was determined using euglycemic hyperinsulinemic clamp (EHGC) before, during the first glucocorticoid infusion and after 2 months of treatment." | 1.35 | Glucocorticoid effect on insulin sensitivity: a time frame. ( Beleslin, B; Ciric, J; Drezgic, M; Penezic, Z; Savic, S; Stojkovic, M; Trbojevic, B; Zarkovic, M, 2008) |
"Hyperlipidemia was observed between the 4th month and the end of the first year after transplantation in 83% of the patients." | 1.26 | Hyperlipidemias in patients with kidney transplants. ( Brunner, F; Harder, F; Kobza, K; Stähelin, HB; Thiel, G, 1976) |
Research
Studies (13)
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 7 (53.85) | 18.7374 |
1990's | 1 (7.69) | 18.2507 |
2000's | 4 (30.77) | 29.6817 |
2010's | 1 (7.69) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors
Authors | Studies |
---|---|
van Raalte, DH | 1 |
van Genugten, RE | 1 |
Linssen, MM | 1 |
Ouwens, DM | 1 |
Diamant, M | 1 |
Semiz, S | 1 |
Bircan, I | 1 |
Akçurin, S | 1 |
Mihçi, E | 1 |
Melikoglu, M | 1 |
Karagüzel, G | 1 |
Kiliçaslan, B | 1 |
Karpuzoğlu, G | 1 |
Zenda, T | 1 |
Murase, Y | 1 |
Yoshida, I | 1 |
Muramoto, H | 1 |
Okada, T | 1 |
Yagi, K | 1 |
ALAJOUANINE, T | 1 |
NEHLIL, J | 1 |
CONTAMIN, F | 1 |
CATHALA, HP | 1 |
Dessein, PH | 1 |
Joffe, BI | 1 |
Stanwix, AE | 1 |
Christian, BF | 1 |
Veller, M | 1 |
Zarkovic, M | 1 |
Beleslin, B | 1 |
Ciric, J | 1 |
Penezic, Z | 1 |
Stojkovic, M | 1 |
Trbojevic, B | 1 |
Drezgic, M | 1 |
Savic, S | 1 |
Kailin, X | 1 |
Yushu, H | 1 |
Qingchao, W | 1 |
Yuanbo, L | 1 |
Stähelin, HB | 1 |
Kobza, K | 1 |
Brunner, F | 1 |
Harder, F | 1 |
Thiel, G | 1 |
Shames, JM | 1 |
Dhurandhar, NR | 1 |
Blackard, WG | 1 |
Fischer, HU | 1 |
Schütze, I | 1 |
Bannert, N | 1 |
Wüstenberg, PW | 1 |
O'Brien, D | 1 |
Creutzfeldt, W | 1 |
Frerichs, H | 1 |
Clinical Trials (1)
Trial Overview
Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
---|---|---|---|---|---|---|---|
Prednisolone-induced Impairment of Glucose Metabolism and Beta-cell Dysfunction and the Protective Effects of Exenatide: a Single-center, Randomized, Double-blind, Placebo-controlled Crossover Study in Healthy Volunteers[NCT00744224] | 8 participants (Anticipated) | Interventional | 2009-02-28 | Completed | |||
[information is prepared from clinicaltrials.gov, extracted Sep-2024] |
Reviews
1 review available for prednisone and Hyperinsulinism
Article | Year |
---|---|
[The hypoglycemia syndrome].
Topics: Alloxan; Angiography; Antibiotics, Antineoplastic; Blood Glucose; Diagnosis, Differential; Diazoxide | 1970 |
Trials
1 trial available for prednisone and Hyperinsulinism
Article | Year |
---|---|
Glucagon-like peptide-1 receptor agonist treatment prevents glucocorticoid-induced glucose intolerance and islet-cell dysfunction in humans.
Topics: Adolescent; Adult; Blood Glucose; C-Peptide; Cross-Over Studies; Exenatide; Glucagon-Like Peptide 1; | 2011 |
Other Studies
11 other studies available for prednisone and Hyperinsulinism
Article | Year |
---|---|
Persistent hyperinsulinaemic hypoglycaemia of infancy: case report.
Topics: Anti-Inflammatory Agents; Blood Glucose; Consanguinity; Diazoxide; Epilepsy; Glucagon; Humans; Hyper | 2002 |
Does the use of insulin in a patient with liver dysfunction increase water retention in the body, i.e. cause insulin oedema?
Topics: Aged; Anti-Inflammatory Agents; Diabetes Mellitus, Type 2; Edema; Female; Hepatitis, Autoimmune; Hum | 2003 |
[Hypoglycemic brain disease caused by probable islet adenoma; disappearance of the disorders under the effect of corticotherapy].
Topics: Adenoma; Brain; Brain Diseases; Hyperinsulinism; Hypoglycemic Agents; Islets of Langerhans; Neoplasm | 1959 |
Glucocorticoids and insulin sensitivity in rheumatoid arthritis.
Topics: Arthritis, Rheumatoid; Cardiovascular Diseases; Female; Glucocorticoids; Humans; Hyperinsulinism; Ma | 2004 |
Glucocorticoid effect on insulin sensitivity: a time frame.
Topics: Adult; Glucocorticoids; Glucose Clamp Technique; Graves Ophthalmopathy; Humans; Hyperinsulinism; Ins | 2008 |
Hyperinsulinemia accompanying hyperglycemia in Chinese patients with aplastic anemia.
Topics: Adolescent; Adult; Aged; Anabolic Agents; Anemia, Aplastic; Blood Glucose; Female; Glucagon; Glucoco | 1997 |
Hyperlipidemias in patients with kidney transplants.
Topics: Age Factors; Body Weight; Follow-Up Studies; Glomerular Filtration Rate; Humans; Hyperinsulinism; Hy | 1976 |
Insulin-secreting bronchial carcinoid tumor with widespread metastases.
Topics: Adult; Blood Glucose; Bronchi; Bronchial Neoplasms; Carcinoma, Adenoid Cystic; Diazoxide; Female; Gl | 1968 |
[Childhood hypoglycemia with convulsions].
Topics: Blood Glucose; Child, Preschool; Electroencephalography; Epinephrine; Fasting; Female; Glucagon; Hum | 1974 |
Management of hypoglycemia.
Topics: Blood Glucose; Child; Dietary Carbohydrates; Ephedrine; Glucose; Humans; Hyperinsulinism; Hypoglycem | 1971 |
[Hypoglycemia factitia. A differential diagnostic significant form of hyperinsulinism].
Topics: Adolescent; Diabetes Mellitus, Type 1; Diabetic Coma; Diagnosis, Differential; Female; Humans; Hyper | 1969 |