Compounds > prednisone
Page last updated: 2024-11-07

prednisone and Hepatic Encephalopathy

prednisone has been researched along with Hepatic Encephalopathy in 37 studies

Prednisone: A synthetic anti-inflammatory glucocorticoid derived from CORTISONE. It is biologically inert and converted to PREDNISOLONE in the liver.
prednisone : A synthetic glucocorticoid drug that is particularly effective as an immunosuppressant, and affects virtually all of the immune system. Prednisone is a prodrug that is converted by the liver into prednisolone (a beta-hydroxy group instead of the oxo group at position 11), which is the active drug and also a steroid.

Hepatic Encephalopathy: A syndrome characterized by central nervous system dysfunction in association with LIVER FAILURE, including portal-systemic shunts. Clinical features include lethargy and CONFUSION (frequently progressing to COMA); ASTERIXIS; NYSTAGMUS, PATHOLOGIC; brisk oculovestibular reflexes; decorticate and decerebrate posturing; MUSCLE SPASTICITY; and bilateral extensor plantar reflexes (see REFLEX, BABINSKI). ELECTROENCEPHALOGRAPHY may demonstrate triphasic waves. (From Adams et al., Principles of Neurology, 6th ed, pp1117-20; Plum & Posner, Diagnosis of Stupor and Coma, 3rd ed, p222-5)

Research Excerpts

ExcerptRelevanceReference
"Classical features of autoimmune hepatitis (AIH) may be altered during the abrupt onset of the disease."1.42Fulminant presentation of autoimmune hepatitis: clinical features and early predictors of corticosteroid treatment failure. ( Anders, M; Balderramo, DC; Barrabino, M; Gadano, A; Gil, O; Marciano, S; Mastai, R; Mendizabal, M; Silva, MO; Tisi Baña, MR; Videla, MG; Yantorno, S; Zerega, A, 2015)
" Two patients developed exacerbation of hepatitis when the dosage of prednisolone was reduced after they had ten weeks of high dose prednisolone."1.29Exacerbation of hepatitis in hepatitis B carriers following chemotherapy for haematological malignancies. ( Chong, R; Goh, YT; Lee, LH; Ng, HS; Tan, P; Wong, GC, 1996)
"Subsequent courses of treatment after relapse were equally effective in again inducing remission, but the probability of another relapse increased after each successive therapy and was 86% after three treatments."1.26Clinical features and prognosis of severe chronic active liver disease (CALD) after corticosteroid-induced remission. ( Ammon, HV; Czaja, AJ; Summerskill, WH, 1980)

Research

Studies (37)

TimeframeStudies, this research(%)All Research%
pre-199030 (81.08)18.7374
1990's2 (5.41)18.2507
2000's1 (2.70)29.6817
2010's3 (8.11)24.3611
2020's1 (2.70)2.80

Authors

AuthorsStudies
Okello, CD1
Omoding, A1
Ddungu, H1
Mulumba, Y1
Orem, J1
Mendizabal, M1
Marciano, S1
Videla, MG1
Anders, M1
Zerega, A1
Balderramo, DC1
Tisi Baña, MR1
Barrabino, M1
Gil, O1
Mastai, R1
Yantorno, S1
Gadano, A1
Silva, MO1
Kuramitsu, K1
Fukumoto, T1
Yano, Y1
Hirano, H1
Misumi, T1
Katayama, Y1
Kawano, H1
Yakushijin, K1
Zen, Y1
Itoh, T1
Ku, Y1
Fujiwara, K1
Yasui, S1
Yokosuka, O1
HULT, H1
SCHMIDT, E1
SCHMIDT, FW1
STERNBERG, MS1
HAGEDORN, CW1
KALSER, MH1
GAMBIGLIANI-ZOCCOLI, A1
COMOLI, G1
MUEHLER, E1
GROS, H1
NELSON, RS2
DEELIZALDE, R1
FIOCCA, S1
NAVASSA, G1
DOUVRES, PA1
ROSENTHAL, WS1
METZGER, P1
TCHERTKOFF, V1
Atiq, M1
Holt, AF1
Safdar, K1
Weber, F1
Ravinuthala, R1
Jonas, ME1
Neff, GW1
Meihoff, WE1
Pasquale, DN1
Jacoby, WJ1
Krebs, R1
Flynn, M1
Baumgarten, R1
Fengler, JD1
Markus, R1
Czaja, AJ1
Ammon, HV1
Summerskill, WH1
Boroń, P1
Szpakowicz, T1
Borzuchowska, A1
Prokopowicz, D1
Nadowska, K1
Bobrowska, E1
Boroń-Kaczmarska, A1
Rzewnicki, I1
Miegoć, H1
Wong, GC1
Tan, P1
Goh, YT1
Ng, HS1
Chong, R1
Lee, LH1
Theodor, E1
Niv, Y1
Maier, KP1
Talke, H1
Gerok, W1
Ritland, S1
Gordon, RD1
Fung, J1
Tzakis, AG1
Todo, S1
Stieber, A1
Bronsther, O1
Martin, M1
Van Thiel, DH1
Starzl, TE1
Lebovics, E1
Schaffner, F1
Klion, FM1
Simon, C1
Lanza, FL1
Ziegler, K1
Rogers, AI1
Lüthy, R1
Berchthold, P1
Siegenthaler, G1
Lawniczak, C1
Seidel, K1
Teske, G1
Teichmann, W1
McKechnie, JC1
Hersh, T1
Lederman, RJ1
Davis, FB1
Davis, PJ1
Ogunlesi, TO1
Dyk, T1
Wasowski, J1
Gruca, Z1
Krebs, RA1
Del Solar, V1
Lobo, G1
Varela, N1
Lehmann, C1

Reviews

2 reviews available for prednisone and Hepatic Encephalopathy

ArticleYear
[THE THERAPY OF LIVER DISEASES].
    Minerva medica, 1963, Sep-22, Volume: 54

    Topics: Alcoholism; Cholangitis; Diet; Diet Therapy; Diuretics; Hepatic Encephalopathy; Hepatitis; Hepatitis

1963
Therapeutic considerations in selected forms of acute and chronic liver disease.
    The Medical clinics of North America, 1971, Volume: 55, Issue:2

    Topics: Acute Disease; Age Factors; Alcoholism; Azathioprine; Chemical and Drug Induced Liver Injury; Chroni

1971

Trials

1 trial available for prednisone and Hepatic Encephalopathy

ArticleYear
Liver transplantation at the University of Pittsburgh, 1984 to 1990.
    Clinical transplants, 1991

    Topics: Adolescent; Age Factors; Body Weight; Child; Child, Preschool; Cyclosporine; Graft Survival; Hepatic

1991

Other Studies

34 other studies available for prednisone and Hepatic Encephalopathy

ArticleYear
Outcomes of treatment with CHOP and EPOCH in patients with HIV associated NHL in a low resource setting.
    BMC cancer, 2020, Aug-24, Volume: 20, Issue:1

    Topics: Adult; Anemia; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Doxorubicin; Drug A

2020
Fulminant presentation of autoimmune hepatitis: clinical features and early predictors of corticosteroid treatment failure.
    European journal of gastroenterology & hepatology, 2015, Volume: 27, Issue:6

    Topics: Adult; Anti-Inflammatory Agents; Factor V; Female; Hepatic Encephalopathy; Hepatitis, Autoimmune; Hu

2015
A case of intravascular lymphoma diagnosed in an explanted liver after liver transplantation.
    Transplant international : official journal of the European Society for Organ Transplantation, 2015, Volume: 28, Issue:10

    Topics: Acute Disease; Antigens, CD20; Antigens, Neoplasm; Antineoplastic Combined Chemotherapy Protocols; B

2015
Appropriate diagnostic criteria for fulminant autoimmune hepatitis.
    European journal of gastroenterology & hepatology, 2015, Volume: 27, Issue:10

    Topics: Anti-Inflammatory Agents; Female; Hepatic Encephalopathy; Hepatitis, Autoimmune; Humans; Liver Failu

2015
[Liver cirrhosis; diagnosis, therapy, portacaval encephalopathy].
    Nordisk medicin, 1958, Dec-04, Volume: 60, Issue:49

    Topics: Central Nervous System Diseases; Diet; Hepatic Encephalopathy; Liver Cirrhosis; Portal System; Predn

1958
[ENZYME DETERMINATIONS IN THE SERUM IN LIVER DISEASES. FUNCTION PATTERNS AS A MEANS OF DIAGNOSIS].
    Enzymologia biologica et clinica, 1963, Volume: 79

    Topics: Alanine Transaminase; Alkaline Phosphatase; Aspartate Aminotransferases; Bilirubin; Cholecystitis; C

1963
THE USE OF SPIRONOLACTONE AND LARGE DOSES OF STEROIDS IN THE TREATMENT OF ASCITES OF LIVER DISEASE.
    Southern medical journal, 1963, Volume: 56

    Topics: Adrenal Cortex Hormones; Ascites; Chlorothiazide; Diuresis; Hepatic Encephalopathy; Humans; Hyponatr

1963
[NEUROLOGIC COMPLICATIONS OF VIRAL HEPATITIS].
    Deutsche medizinische Wochenschrift (1946), 1964, May-08, Volume: 89

    Topics: Adolescent; Athetosis; Chorea; Encephalitis; Hepatic Encephalopathy; Hepatitis; Hepatitis A; Humans;

1964
HEPATITIS AND--MALIGNANT NEOPLASIA.
    Medical times, 1964, Volume: 92

    Topics: Biopsy; Drug Therapy; Hepatic Encephalopathy; Hepatitis; Hepatitis A; Humans; Hydrocortisone; Hyperb

1964
[CLINICAL AND HISTOPATHOLOGICAL ASPECTS OF INTRAHEPATIC CHOLESTASIS].
    Minerva medica, 1964, Jul-28, Volume: 55

    Topics: Anti-Bacterial Agents; Chemical and Drug Induced Liver Injury; Cholestasis, Intrahepatic; Diabetes M

1964
ACUTE FATTY LIVER OF PREGNANCY WITH HEPATIC COMA AND MALLORY-WEISS SYNDROME: REPORT OF A CASE.
    The American journal of digestive diseases, 1965, Volume: 10

    Topics: Ammonia; Blood; Drug Therapy; Fatty Liver; Female; Gastric Mucosa; Gastrointestinal Hemorrhage; Hepa

1965
Adult onset urea cycle disorder in a patient with presumed hepatic encephalopathy.
    Journal of clinical gastroenterology, 2008, Volume: 42, Issue:2

    Topics: Diagnosis, Differential; Glucocorticoids; Hepatic Encephalopathy; Humans; Hyperammonemia; Male; Meta

2008
Tetracycline-induced hepatic coma, with recovery. Report of a case.
    Obstetrics and gynecology, 1967, Volume: 29, Issue:2

    Topics: Adult; Female; Hepatic Encephalopathy; Humans; Prednisolone; Prednisone; Pregnancy; Pregnancy Compli

1967
Treatment of hepatic coma with exchange transfusion and peritoneal dialysis.
    JAMA, 1967, Feb-06, Volume: 199, Issue:6

    Topics: Adolescent; Bilirubin; Exchange Transfusion, Whole Blood; Hematocrit; Hepatic Encephalopathy; Hepati

1967
[Early diagnosis and therapy of hepatic coma in viral hepatitis--theoretical concepts and practical possibilities].
    Zeitschrift fur arztliche Fortbildung, 1982, Apr-01, Volume: 76, Issue:7

    Topics: Amino Acids; Exchange Transfusion, Whole Blood; Hepatic Encephalopathy; Hepatitis, Viral, Human; Hum

1982
Clinical features and prognosis of severe chronic active liver disease (CALD) after corticosteroid-induced remission.
    Gastroenterology, 1980, Volume: 78, Issue:3

    Topics: Azathioprine; Biopsy; Chronic Disease; Drug Therapy, Combination; Follow-Up Studies; Hepatic Encepha

1980
[Critical analysis of complex therapeutic methods in acute hepatic insufficiency with encephalopathy in the course of viral hepatitis].
    Polskie Archiwum Medycyny Wewnetrznej, 1980, Volume: 63, Issue:4

    Topics: Adult; Aged; Evaluation Studies as Topic; Exchange Transfusion, Whole Blood; Female; Heparin; Hepati

1980
Exacerbation of hepatitis in hepatitis B carriers following chemotherapy for haematological malignancies.
    Annals of the Academy of Medicine, Singapore, 1996, Volume: 25, Issue:4

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carrier State; Chronic Disea

1996
The clinical course of subacute hepatic necrosis.
    The American journal of gastroenterology, 1978, Volume: 70, Issue:6

    Topics: Adolescent; Adult; Age Factors; Aged; Alkaline Phosphatase; Child; Female; Follow-Up Studies; Hepati

1978
[Glucocorticoids in chronic liver diseases].
    Deutsche medizinische Wochenschrift (1946), 1975, Mar-14, Volume: 100, Issue:11

    Topics: Alcoholism; Ascites; Chronic Disease; Fatty Liver; Female; Glucocorticoids; Hepatic Encephalopathy;

1975
[Medical treatment of liver cirrhosis].
    Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 1976, Mar-20, Volume: 96, Issue:8

    Topics: Adrenal Cortex Hormones; Ascites; Diuretics; Hepatic Encephalopathy; Humans; Liver Cirrhosis; Neomyc

1976
Autoimmune chronic active hepatitis in postmenopausal women.
    Digestive diseases and sciences, 1985, Volume: 30, Issue:9

    Topics: Aged; Antibodies, Antinuclear; Ascites; Autoimmune Diseases; Azathioprine; Diabetes Mellitus; Drug T

1985
Steroid therapy in massive hepatic necrosis due to viral hepatitis.
    Southern medical journal, 1970, Volume: 63, Issue:12

    Topics: Adult; Female; Hepatic Encephalopathy; Hepatitis A; Hepatitis B; Hepatovirus; Humans; Male; Middle A

1970
[Current views on the therapy of hepatic coma].
    Zeitschrift fur die gesamte innere Medizin und ihre Grenzgebiete, 1970, Apr-15, Volume: 25, Issue:8

    Topics: Acute Kidney Injury; Adolescent; Amino Acids; Ammonia; Anti-Bacterial Agents; Arginine; Aspartic Aci

1970
[Pathophysiology, clinical course, differential diagnosis and therapy of hepatic coma].
    Schweizerische Rundschau fur Medizin Praxis = Revue suisse de medecine Praxis, 1971, Oct-12, Volume: 60, Issue:41

    Topics: Brain Diseases; Diagnosis, Differential; Glucose; Hepatic Encephalopathy; Humans; Liver Transplantat

1971
[A case of hepatic coma in the 2d trimester of pregnancy with a favorable outcome for the mother and fetus].
    Wiadomosci lekarskie (Warsaw, Poland : 1960), 1969, Sep-01, Volume: 22, Issue:17

    Topics: Adult; Anti-Bacterial Agents; Female; Hepatic Encephalopathy; Hepatitis A; Humans; Prednisone; Pregn

1969
[Cross-circulation in the treatment of hepatic coma].
    German medical monthly, 1969, Volume: 14, Issue:9

    Topics: Adolescent; Autopsy; Colitis, Ulcerative; Diagnosis, Differential; Female; Hepatic Encephalopathy; H

1969
[Reflections on prednisone therapy of patients with liver diseases].
    Deutsche Zeitschrift fur Verdauungs- und Stoffwechselkrankheiten, 1970, Volume: 30, Issue:1

    Topics: Bilirubin; Chronic Disease; Depression, Chemical; Gluconeogenesis; Hepatic Encephalopathy; Hepatitis

1970
Exchange transfusion in hepatic coma. A review of 19 cases.
    The American journal of gastroenterology, 1971, Volume: 56, Issue:1

    Topics: Adolescent; Adult; Alanine Transaminase; Ammonia; Anesthesia, Inhalation; Autopsy; Bilirubin; Blood

1971
Exchange transfusion as treatment of acute hepatic failure due to antituberculosis drugs.
    Annals of internal medicine, 1968, Volume: 68, Issue:4

    Topics: Acute Disease; Adult; Aminosalicylic Acids; Chemical and Drug Induced Liver Injury; Eosinophilia; Et

1968
Hepatic failure in the tropics.
    British medical journal, 1968, Jun-29, Volume: 2, Issue:5608

    Topics: Acute Disease; Adolescent; Adult; Africa; Aged; Carcinoma; Chronic Disease; Diet; Female; Hepatic En

1968
[Severe hepatic coma in a patient with chronic pancreatitis cured with cortisone. Death due to acute pancreatic necrosis (pancreatitis steroides)].
    Polski tygodnik lekarski (Warsaw, Poland : 1960), 1968, Sep-05, Volume: 23, Issue:32

    Topics: Adult; Cortisone; Hepatic Encephalopathy; Hepatitis A; Humans; Male; Necrosis; Pancreatitis; Prednis

1968
Hepatic coma. Three-year follow-up after exchange transfusion and peritoneal dialysis.
    JAMA, 1969, May-26, Volume: 208, Issue:8

    Topics: Adolescent; Chronic Disease; Exchange Transfusion, Whole Blood; Hepatic Encephalopathy; Hepatitis; H

1969
[Treatment of ascites in cirrhosis of the liver].
    Revista medica de Chile, 1965, Volume: 93, Issue:9

    Topics: Adult; Aged; Ascites; Diuretics; Female; Hepatic Encephalopathy; Humans; Liver Cirrhosis; Male; Mety

1965