prednisone and HIV
prednisone has been researched along with HIV in 19 studies
Prednisone: A synthetic anti-inflammatory glucocorticoid derived from CORTISONE. It is biologically inert and converted to PREDNISOLONE in the liver.
prednisone : A synthetic glucocorticoid drug that is particularly effective as an immunosuppressant, and affects virtually all of the immune system. Prednisone is a prodrug that is converted by the liver into prednisolone (a beta-hydroxy group instead of the oxo group at position 11), which is the active drug and also a steroid.
HIV: Human immunodeficiency virus. A non-taxonomic and historical term referring to any of two species, specifically HIV-1 and/or HIV-2. Prior to 1986, this was called human T-lymphotropic virus type III/lymphadenopathy-associated virus (HTLV-III/LAV). From 1986-1990, it was an official species called HIV. Since 1991, HIV was no longer considered an official species name; the two species were designated HIV-1 and HIV-2.
Research Excerpts
| Excerpt | Relevance | Reference |
|---|---|---|
| "To examine the effect of 2 weeks of treatment with prednisone on the incidence of nevirapine-associated rash in HIV-1-infected patients receiving combination antiretroviral therapy." | 9.10 | Randomized, controlled study of the effects of a short course of prednisone on the incidence of rash associated with nevirapine in patients infected with HIV-1. ( Cahn, P; Casssetti, LI; Gigliotti, M; Hall, DB; Losso, M; McDonough, M; Montaner, JS; Robinson, PA; Wruck, J; Zala, C, 2003) |
| "This is a phase 2 study to assess the role of tumor histogenesis (subtype), fluorodeoxyglucose positron emission tomography (FDG-PET), and short-course etoposide, prednisone, vincristine, cyclophosphamide, and doxorubicin with dose-dense rituximab (SC-EPOCH-RR) in newly diagnosed HIV-associated CD20(+) diffuse large B-cell lymphoma." | 5.14 | The role of tumor histogenesis, FDG-PET, and short-course EPOCH with dose-dense rituximab (SC-EPOCH-RR) in HIV-associated diffuse large B-cell lymphoma. ( Carrasquillo, JA; Dunleavy, K; Grant, N; Jaffe, ES; Little, RF; Pittaluga, S; Steinberg, SM; Wayne, AS; Wilson, WH; Yarchoan, R, 2010) |
| "To examine the effect of 2 weeks of treatment with prednisone on the incidence of nevirapine-associated rash in HIV-1-infected patients receiving combination antiretroviral therapy." | 5.10 | Randomized, controlled study of the effects of a short course of prednisone on the incidence of rash associated with nevirapine in patients infected with HIV-1. ( Cahn, P; Casssetti, LI; Gigliotti, M; Hall, DB; Losso, M; McDonough, M; Montaner, JS; Robinson, PA; Wruck, J; Zala, C, 2003) |
| " Our study aimed to investigate the prognosis and compare outcome of dose-adjusted etoposide, prednisone, vincristine, cyclophosphamide, doxorubicin, and rituximab (DA-EPOCH-R) with standard cyclophosphamide, doxorubicin, vincristine, prednisone and rituximab(R-CHOP) as front line therapy for PLHIV with diffuse large B-cell lymphoma (DLBCL) receiving modern combined antiretroviral therapy (cART)." | 3.96 | Clinical outcomes of people living with human immunodeficiency virus (HIV) with diffuse large B-cell lymphoma (DLBCL) in Shanghai, China. ( Chen, J; Liu, L; Qi, TK; Shen, YZ; Song, W; Sun, JJ; Tang, Y; Wang, JR; Wang, ZY; Zhang, RF, 2020) |
| "Limited comparative data exist for the treatment of HIV-associated non-Hodgkin lymphoma." | 2.49 | Treatment factors affecting outcomes in HIV-associated non-Hodgkin lymphomas: a pooled analysis of 1546 patients. ( Barta, SK; Boue, F; Dunleavy, K; Galicier, L; Garcia, O; Kaplan, LD; Lee, JY; Little, RF; Morgades, M; Mounier, N; Navarro, JT; Noy, A; Oriol, A; Ratner, L; Remick, SC; Ribera, JM; Sparano, JA; Spina, M; Tamari, R; Tirelli, U; Wang, D; Weiss, R; Wilson, WH; Wyen, C; Xue, X, 2013) |
Research
Studies (19)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (10.53) | 18.7374 |
| 1990's | 2 (10.53) | 18.2507 |
| 2000's | 6 (31.58) | 29.6817 |
| 2010's | 5 (26.32) | 24.3611 |
| 2020's | 4 (21.05) | 2.80 |
Authors
| Authors | Studies |
|---|---|
| Rapiti, N | 1 |
| Abdelatif, N | 1 |
| Rapiti, A | 1 |
| Moosa, MY | 1 |
| Sun, JJ | 1 |
| Liu, L | 1 |
| Wang, JR | 1 |
| Shen, YZ | 1 |
| Qi, TK | 1 |
| Wang, ZY | 1 |
| Tang, Y | 1 |
| Song, W | 1 |
| Chen, J | 1 |
| Zhang, RF | 1 |
| Ke, YL | 1 |
| Hsiao, HH | 1 |
| Cho, SF | 1 |
| Wu, CC | 1 |
| Harrison, MJ | 1 |
| Brice, N | 1 |
| Scott, C | 1 |
| Barta, SK | 1 |
| Xue, X | 1 |
| Wang, D | 1 |
| Tamari, R | 1 |
| Lee, JY | 2 |
| Mounier, N | 1 |
| Kaplan, LD | 2 |
| Ribera, JM | 1 |
| Spina, M | 2 |
| Tirelli, U | 2 |
| Weiss, R | 1 |
| Galicier, L | 1 |
| Boue, F | 1 |
| Wilson, WH | 2 |
| Wyen, C | 1 |
| Oriol, A | 1 |
| Navarro, JT | 1 |
| Dunleavy, K | 2 |
| Little, RF | 2 |
| Ratner, L | 2 |
| Garcia, O | 1 |
| Morgades, M | 1 |
| Remick, SC | 2 |
| Noy, A | 2 |
| Sparano, JA | 2 |
| Koizumi, Y | 1 |
| Uehira, T | 1 |
| Ota, Y | 1 |
| Ogawa, Y | 1 |
| Yajima, K | 1 |
| Tanuma, J | 1 |
| Yotsumoto, M | 1 |
| Hagiwara, S | 1 |
| Ikegaya, S | 1 |
| Watanabe, D | 1 |
| Minamiguchi, H | 1 |
| Hodohara, K | 1 |
| Murotani, K | 1 |
| Mikamo, H | 1 |
| Wada, H | 1 |
| Ajisawa, A | 1 |
| Shirasaka, T | 1 |
| Nagai, H | 1 |
| Kodama, Y | 1 |
| Hishima, T | 1 |
| Mochizuki, M | 1 |
| Katano, H | 1 |
| Okada, S | 1 |
| Andhavarapu, S | 1 |
| Tolentino, AM | 1 |
| Jha, C | 1 |
| Ravi, J | 1 |
| Carlson, R | 1 |
| Nair, GR | 1 |
| Levine, AM | 1 |
| Ramos, JC | 1 |
| Ambinder, RF | 1 |
| Wachsman, W | 1 |
| Aboulafia, D | 1 |
| Henry, DH | 1 |
| Von Roenn, J | 1 |
| Dezube, BJ | 1 |
| Shah, MH | 1 |
| Leichman, L | 1 |
| Cesarman, E | 1 |
| Chadburn, A | 1 |
| Mitsuyasu, R | 1 |
| Pittaluga, S | 1 |
| Grant, N | 1 |
| Wayne, AS | 1 |
| Carrasquillo, JA | 1 |
| Steinberg, SM | 1 |
| Yarchoan, R | 1 |
| Jaffe, ES | 1 |
| Mihaljevic, BS | 1 |
| Todorovic, MR | 1 |
| Andjelic, BM | 1 |
| Antic, DA | 1 |
| Perunicic Jovanovic, MD | 1 |
| Montaner, JS | 1 |
| Cahn, P | 1 |
| Zala, C | 1 |
| Casssetti, LI | 1 |
| Losso, M | 1 |
| Hall, DB | 1 |
| Wruck, J | 1 |
| McDonough, M | 1 |
| Gigliotti, M | 1 |
| Robinson, PA | 1 |
| Tavel, JA | 1 |
| Sereti, I | 1 |
| Walker, RE | 1 |
| Hahn, B | 1 |
| Kovacs, JA | 1 |
| Jagannatha, S | 1 |
| Davey, RT | 1 |
| Falloon, J | 1 |
| Polis, MA | 1 |
| Masur, H | 1 |
| Metcalf, JA | 1 |
| Stevens, R | 1 |
| Rupert, A | 1 |
| Baseler, M | 1 |
| Lane, HC | 1 |
| Youngster, I | 1 |
| Vaisben, E | 1 |
| Cohen, H | 1 |
| Nassar, F | 1 |
| Rossi, G | 1 |
| Donisi, A | 1 |
| Casari, S | 1 |
| Re, A | 1 |
| Stellini, R | 1 |
| Cadeo, G | 1 |
| Carosi, G | 1 |
| Gabarre, J | 1 |
| Fasan, M | 1 |
| Vaccher, E | 1 |
| Cornfield, DB | 1 |
| Papiez, JS | 1 |
| Lynch, JT | 1 |
| Rimsza, LM | 1 |
| Miller, RG | 1 |
| Laurence, J | 1 |
| Sellers, MB | 1 |
| Sikder, SK | 1 |
| Kerman, RH | 1 |
| Flechner, SM | 1 |
| Van Buren, CT | 1 |
| Lorber, MI | 1 |
| Dawson, G | 1 |
| Falk, L | 1 |
| Gutierrez, R | 1 |
| Hollinger, JB | 1 |
| Kahan, BD | 1 |
Clinical Trials (2)
Trial Overview
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Randomized Phase II Trial of EPOCH Given Either Concurrently or Sequentially With Rituximab in Patients With Intermediate- or High-Grade HIV-Associated B-cell Non-Hodgkin's Lymphoma[NCT00049036] | Phase 2 | 106 participants (Actual) | Interventional | 2003-03-31 | Completed | ||
| EPOCH Chemotherapy Plus Rituximab for Previously Treated Patients With AIDS-Associated Lymphoma[NCT00001563] | Phase 2 | 39 participants (Actual) | Interventional | 1997-01-08 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Trial Outcomes
Complete Response Proportion as Measured by Tumor Response After Completion of Study Treatment
Complete response defined by the International Response Criteria for Non-Hodgkin's Lymphoma (NCT00049036)
Timeframe: 60 days
| Intervention | proportion (Number) |
|---|---|
| EPOCH + Concurrent Rituximab | 0.69 |
| EPOCH Followed by Rituximab | 0.53 |
Reviews
4 reviews available for prednisone and HIV
| Article | Year |
|---|---|
Patient characteristics and outcome of CD20-positive HIV-associated lymphoma: a single-center KwaZulu-Natal, South African hospital 12-year retrospective review.
Topics: Adult; Antibodies, Monoclonal, Murine-Derived; Antineoplastic Combined Chemotherapy Protocols; Cyclo | 2022 |
Clinical Features of HIV Arthropathy in Children: A Case Series and Literature Review.
Topics: Anti-HIV Agents; Anti-Inflammatory Agents, Non-Steroidal; Antirheumatic Agents; Arthritis; CD4 Lymph | 2021 |
Treatment factors affecting outcomes in HIV-associated non-Hodgkin lymphomas: a pooled analysis of 1546 patients.
Topics: Anti-HIV Agents; Antibodies, Monoclonal, Murine-Derived; Antineoplastic Agents; Antineoplastic Combi | 2013 |
Neuropathies and myopathies complicating HIV infection.
Topics: Acquired Immunodeficiency Syndrome; Action Potentials; Adult; Antiviral Agents; Azathioprine; Combin | 1991 |
Trials
6 trials available for prednisone and HIV
| Article | Year |
|---|---|
Rituximab plus concurrent infusional EPOCH chemotherapy is highly effective in HIV-associated B-cell non-Hodgkin lymphoma.
Topics: Adult; Antibodies, Monoclonal; Antibodies, Monoclonal, Murine-Derived; Antineoplastic Agents; Antine | 2010 |
The role of tumor histogenesis, FDG-PET, and short-course EPOCH with dose-dense rituximab (SC-EPOCH-RR) in HIV-associated diffuse large B-cell lymphoma.
Topics: Adolescent; Adult; Antibodies, Monoclonal; Antibodies, Monoclonal, Murine-Derived; Antineoplastic Ag | 2010 |
Randomized, controlled study of the effects of a short course of prednisone on the incidence of rash associated with nevirapine in patients infected with HIV-1.
Topics: CD4 Lymphocyte Count; Drug Administration Schedule; Exanthema; Female; HIV; HIV Infections; Humans; | 2003 |
A randomized, double-blinded, placebo-controlled trial of intermittent administration of interleukin-2 and prednisone in subjects infected with human immunodeficiency virus.
Topics: Anti-HIV Agents; Antiretroviral Therapy, Highly Active; CD4 Lymphocyte Count; CD4-Positive T-Lymphoc | 2003 |
Effects of recombinant granulocyte colony-stimulating factor (G-CSF) in patients treated with ProMACE-CytaBOM for HIV-related non-Hodgkin's lymphoma (NHL).
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cohort Studies; Cyclophosphamide; | 1998 |
Stanford V regimen and concomitant highly active antiretroviral therapy is feasible and active in patients with Hodgkin's disease and HIV infection.
Topics: Adult; Anti-HIV Agents; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Doxorubicin; Etop | 2000 |
Other Studies
9 other studies available for prednisone and HIV
| Article | Year |
|---|---|
Clinical outcomes of people living with human immunodeficiency virus (HIV) with diffuse large B-cell lymphoma (DLBCL) in Shanghai, China.
Topics: Antineoplastic Combined Chemotherapy Protocols; China; Cyclophosphamide; Doxorubicin; HIV; HIV Infec | 2020 |
A tip of the iceberg: Disseminated plasmablastic lymphoma, diagnosed from a local oral lesion.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Antiretroviral Therapy, Highly Active; Biopsy | 2021 |
Clinical and pathological aspects of human immunodeficiency virus-associated plasmablastic lymphoma: analysis of 24 cases.
Topics: Adult; Anti-Retroviral Agents; Antineoplastic Combined Chemotherapy Protocols; CD4 Lymphocyte Count; | 2016 |
Diffuse large B-cell lymphoma presenting as multiple lymphomatous polyposis of the gastrointestinal tract.
Topics: Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Diagnosis, Differential; Doxorubic | 2008 |
Unusual presentation of gastric plasmablastic lymphoma in HIV-negative patient.
Topics: Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Doxorubicin; HIV; HIV Infections; | 2012 |
An unusual cause of pleural effusion.
Topics: Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Diagnosis, Diff | 2006 |
Natural killer-like T-cell lymphoma of the parotid in a patient infected with human immunodeficiency virus.
Topics: Adult; Antigens, CD; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Cyclophospha | 2002 |
Effect of glucocorticoids on chronic human immunodeficiency virus (HIV) infection and HIV promoter-mediated transcription.
Topics: Acquired Immunodeficiency Syndrome; Cell Division; Cell Line; Dexamethasone; Gene Expression Regulat | 1989 |
Investigation of HTLV-3 serology in a renal transplant population.
Topics: Antibodies, Viral; Azathioprine; Blood Transfusion; Cyclosporins; Histocompatibility Testing; HIV; H | 1987 |