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prednisone and HIV Wasting Syndrome

prednisone has been researched along with HIV Wasting Syndrome in 2 studies

Prednisone: A synthetic anti-inflammatory glucocorticoid derived from CORTISONE. It is biologically inert and converted to PREDNISOLONE in the liver.
prednisone : A synthetic glucocorticoid drug that is particularly effective as an immunosuppressant, and affects virtually all of the immune system. Prednisone is a prodrug that is converted by the liver into prednisolone (a beta-hydroxy group instead of the oxo group at position 11), which is the active drug and also a steroid.

HIV Wasting Syndrome: Involuntary weight loss of greater than 10 percent associated with intermittent or constant fever and chronic diarrhea or fatigue for more than 30 days in the absence of a defined cause other than HIV infection. A constant feature is major muscle wasting with scattered myofiber degeneration. A variety of etiologies, which vary among patients, contributes to this syndrome. (From Harrison's Principles of Internal Medicine, 13th ed, p1611).

Research Excerpts

ExcerptRelevanceReference
"In an exploratory study of virologic and immunomodulatory effects of corticosteroid therapy for wasting syndrome, four HIV-infected adults with recent unexplained weight loss were given tapering doses of prednisone over a 2-month period."9.08Effects of tapering doses of oral prednisone on viral load among HIV-infected patients with unexplained weight loss. ( Bucy, RP; Kilby, JM; Mulanovich, V; Saag, MS; Shaw, GM; Tabereaux, PB, 1997)
"In an exploratory study of virologic and immunomodulatory effects of corticosteroid therapy for wasting syndrome, four HIV-infected adults with recent unexplained weight loss were given tapering doses of prednisone over a 2-month period."5.08Effects of tapering doses of oral prednisone on viral load among HIV-infected patients with unexplained weight loss. ( Bucy, RP; Kilby, JM; Mulanovich, V; Saag, MS; Shaw, GM; Tabereaux, PB, 1997)
" Patients with polyarteritis nodosa (two) or polymyositis (one) were treated with prednisone, which improved their wasting syndrome."3.69Skeletal muscle studies in patients with HIV-related wasting syndrome. ( Casademont, J; Cebrián, M; Grau, JM; Mallolas, J; Masanés, F; Miró, O; Pedrol, E, 1997)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (100.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Miró, O1
Pedrol, E1
Cebrián, M1
Masanés, F1
Casademont, J1
Mallolas, J1
Grau, JM1
Kilby, JM1
Tabereaux, PB1
Mulanovich, V1
Shaw, GM1
Bucy, RP1
Saag, MS1

Trials

1 trial available for prednisone and HIV Wasting Syndrome

ArticleYear
Effects of tapering doses of oral prednisone on viral load among HIV-infected patients with unexplained weight loss.
    AIDS research and human retroviruses, 1997, Nov-20, Volume: 13, Issue:17

    Topics: Adult; CD4 Lymphocyte Count; Dose-Response Relationship, Drug; Female; HIV Wasting Syndrome; Humans;

1997

Other Studies

1 other study available for prednisone and HIV Wasting Syndrome

ArticleYear
Skeletal muscle studies in patients with HIV-related wasting syndrome.
    Journal of the neurological sciences, 1997, Sep-10, Volume: 150, Issue:2

    Topics: Adult; Anti-Inflammatory Agents; Azathioprine; Biopsy; Female; HIV Wasting Syndrome; Humans; Immunos

1997