prednisone has been researched along with HELLP Syndrome in 5 studies
Prednisone: A synthetic anti-inflammatory glucocorticoid derived from CORTISONE. It is biologically inert and converted to PREDNISOLONE in the liver.
prednisone : A synthetic glucocorticoid drug that is particularly effective as an immunosuppressant, and affects virtually all of the immune system. Prednisone is a prodrug that is converted by the liver into prednisolone (a beta-hydroxy group instead of the oxo group at position 11), which is the active drug and also a steroid.
HELLP Syndrome: A syndrome of HEMOLYSIS, elevated liver ENZYMES, and low blood platelets count (THROMBOCYTOPENIA). HELLP syndrome is observed in pregnant women with PRE-ECLAMPSIA or ECLAMPSIA who also exhibit LIVER damage and abnormalities in BLOOD COAGULATION.
| Excerpt | Relevance | Reference |
|---|---|---|
| "During pregnancy the placental 11beta-hydroxysteroid dehydrogenase 2 (11beta-HSD2) enzyme inactivates prednisolone by interconversion into prednisone, protecting the fetus from high levels of prednisolone." | 9.11 | The transplacental passage of prednisolone in pregnancies complicated by early-onset HELLP syndrome. ( Bruinse, HW; Franx, A; Huisjes, AJ; Schobben, AF; van Runnard Heimel, PJ, 2005) |
| "During pregnancy the placental 11beta-hydroxysteroid dehydrogenase 2 (11beta-HSD2) enzyme inactivates prednisolone by interconversion into prednisone, protecting the fetus from high levels of prednisolone." | 5.11 | The transplacental passage of prednisolone in pregnancies complicated by early-onset HELLP syndrome. ( Bruinse, HW; Franx, A; Huisjes, AJ; Schobben, AF; van Runnard Heimel, PJ, 2005) |
| "Acute renal failure is a serious complication of pregnancy associated with a high rate of morbidity and mortality; the incidence is currently 1 per 10,000 pregnancies." | 2.45 | [Acute renal failure secondary to hemolytic uremic syndrome in a pregnant woman with pre-eclampsia]. ( Alsina Aser, MJ; García-Miguel, FJ; Mirón Rodríguez, MF, 2009) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (60.00) | 29.6817 |
| 2010's | 1 (20.00) | 24.3611 |
| 2020's | 1 (20.00) | 2.80 |
| Authors | Studies |
|---|---|
| Moutos, CP | 1 |
| Hoyer, P | 1 |
| Kelly, B | 1 |
| Saad, AF | 1 |
| Brucato, A | 1 |
| Imazio, M | 1 |
| Curri, S | 1 |
| Palmieri, G | 1 |
| Trinchero, R | 1 |
| García-Miguel, FJ | 1 |
| Mirón Rodríguez, MF | 1 |
| Alsina Aser, MJ | 1 |
| van Runnard Heimel, PJ | 1 |
| Schobben, AF | 1 |
| Huisjes, AJ | 1 |
| Franx, A | 1 |
| Bruinse, HW | 1 |
| Elchalal, U | 1 |
| Gabbay, E | 1 |
| Nadjari, M | 1 |
| Varon, D | 1 |
| Zelig, O | 1 |
| Ben-Chetrit, E | 1 |
1 review available for prednisone and HELLP Syndrome
| Article | Year |
|---|---|
[Acute renal failure secondary to hemolytic uremic syndrome in a pregnant woman with pre-eclampsia].
Topics: Acute Kidney Injury; Adult; Antihypertensive Agents; Biomarkers; Combined Modality Therapy; Diagnosi | 2009 |
1 trial available for prednisone and HELLP Syndrome
| Article | Year |
|---|---|
The transplacental passage of prednisolone in pregnancies complicated by early-onset HELLP syndrome.
Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 2; Anti-Inflammatory Agents; Female; Fetus; HELLP Syndrome | 2005 |
3 other studies available for prednisone and HELLP Syndrome
| Article | Year |
|---|---|
Pyoderma gangrenosum after cesarean delivery.
Topics: Anti-Bacterial Agents; Biopsy; Cesarean Section; Cyclosporine; Debridement; Diagnosis, Differential; | 2021 |
Medical treatment of pericarditis during pregnancy.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Drug Therapy, Combination; Female; Glucocor | 2010 |
Catastrophic antiphospholipid syndrome in the second trimester of pregnancy.
Topics: Abortion, Induced; Adult; Anti-Inflammatory Agents; Anticoagulants; Antineoplastic Agents, Hormonal; | 2006 |