Page last updated: 2024-11-07

prednisone and Graves Ophthalmopathy

prednisone has been researched along with Graves Ophthalmopathy in 33 studies

Prednisone: A synthetic anti-inflammatory glucocorticoid derived from CORTISONE. It is biologically inert and converted to PREDNISOLONE in the liver.
prednisone : A synthetic glucocorticoid drug that is particularly effective as an immunosuppressant, and affects virtually all of the immune system. Prednisone is a prodrug that is converted by the liver into prednisolone (a beta-hydroxy group instead of the oxo group at position 11), which is the active drug and also a steroid.

Graves Ophthalmopathy: An autoimmune disorder of the EYE, occurring in patients with Graves disease. Subtypes include congestive (inflammation of the orbital connective tissue), myopathic (swelling and dysfunction of the extraocular muscles), and mixed congestive-myopathic ophthalmopathy.

Research Excerpts

ExcerptRelevanceReference
"A 24-year-old Caucasian women with a history of intravenous heroin use was hospitalized for tricuspid valve endocarditis and methicillin-resistant Staphylococcus aureus bacteremia, as well as acute renal failure."4.12REACTIVE AMYLOID A PROTEIN AMYLOIDOSIS IN THE SETTING OF INFECTIVE ENDOCARDITIS MANIFESTING AS BILATERAL ORBITOPATHY AND CHOROIDOPATHY. ( Agarwal, A; Carrera, W; Ng, C; Peng, MY; Rosco, MG; Safo, M, 2022)
"A 55-year-old woman with concurrent active thyroid orbitopathy and B-cell lymphoma developed acute exacerbation of thyroid orbitopathy after receiving Rituximab, cyclophosphamide, hydroxydaunorubicin, Prednisone (R-CHOP) chemotherapy, presenting with subtotal loss of vision and severe eyelid edema."3.88Chemotherapy-induced exacerbations of thyroid orbitopathy in a patient with B-cell lymphoma. ( Croon-de Boer, F; Dalm, VASH; Liu, C; Paridaens, D; van Hagen, PM, 2018)
"For reducing the rate of recurrence, 3 treatments were ranked as follows: radioiodine therapy, therapy with antithyroid drugs and surgery."2.52Comparative Efficacy of Four Treatments in Patients with Graves' Disease: a Network Meta-analysis. ( Li, J; Li, Y; Qin, L; Ren, Z; Wang, JQ; Zhang, RG, 2015)
"Autoimmune reactions in Graves' disease (GD) occur not only in the thyroid gland, but also in the orbital connective tissue, eyelids, extraocular muscles."1.56Radioiodine therapy and Graves' disease - Myths and reality. ( Borowska, M; Czarnywojtek, A; Gut, P; Karlińska, M; Kobylecka, M; Krolicki, L; Plazinska, MT; Prasek, K; Ruchala, M; Sawicka-Gutaj, N; Wolinski, K; Zgorzalewicz-Stachowiak, M, 2020)
"Coexistence of idiopathic orbital inflammatory pseudotumor (IOIP) and thyroid-associated ophthalmopathy (TAO) is extremely rare."1.42Concomitant Idiopathic Orbital Inflammatory Pseudotumor and Thyroid-Associated Ophthalmopathy. ( Chen, J; Lin, J; Liu, R; Shen, T; Yan, J, 2015)
"Prednisone was started 1 d after RAI and withdrawn after 6 wk."1.36Lower dose prednisone prevents radioiodine-associated exacerbation of initially mild or absent graves' orbitopathy: a retrospective cohort study. ( Bartalena, L; Compri, E; Lai, A; Marino, F; Piantanida, E; Sassi, L; Sivelli, P; Tanda, ML, 2010)
"Insulin sensitivity was determined using euglycemic hyperinsulinemic clamp (EHGC) before, during the first glucocorticoid infusion and after 2 months of treatment."1.35Glucocorticoid effect on insulin sensitivity: a time frame. ( Beleslin, B; Ciric, J; Drezgic, M; Penezic, Z; Savic, S; Stojkovic, M; Trbojevic, B; Zarkovic, M, 2008)
" The initial dosage was 1."1.33[Treatment of thyroid-associated ophthalmopathy: comparative study between prednisone and COP therapy]. ( Hu, TS; Jiang, RX; Lian, L; Liu, XP; Min, HY, 2005)

Research

Studies (33)

TimeframeStudies, this research(%)All Research%
pre-19906 (18.18)18.7374
1990's0 (0.00)18.2507
2000's8 (24.24)29.6817
2010's16 (48.48)24.3611
2020's3 (9.09)2.80

Authors

AuthorsStudies
Rosetti, S1
Tanda, ML2
Veronesi, G1
Masiello, E1
Premoli, P1
Gallo, D1
Cusini, C1
Donati, S1
Sabatino, J1
Ippolito, S1
Piantanida, E2
Bartalena, L3
Plazinska, MT1
Sawicka-Gutaj, N1
Czarnywojtek, A1
Wolinski, K1
Kobylecka, M1
Karlińska, M1
Prasek, K1
Zgorzalewicz-Stachowiak, M1
Borowska, M1
Gut, P1
Ruchala, M1
Krolicki, L1
Carrera, W1
Rosco, MG1
Safo, M1
Peng, MY1
Ng, C1
Agarwal, A1
Ambroziak, U1
Bluszcz, G1
Bednarczuk, T1
Miśkiewicz, P1
Liu, C1
Dalm, VASH1
van Hagen, PM1
Croon-de Boer, F1
Paridaens, D1
Salvi, M1
Covelli, D1
Penta, L1
Muzi, G1
Cofini, M1
Leonardi, A1
Lanciotti, L1
Esposito, S1
Tortora, F1
Prudente, M1
Cirillo, M1
Elefante, A1
Belfiore, MP1
Romano, F1
Cappabianca, S1
Carella, C1
Cirillo, S1
Zhu, W1
Ye, L1
Shen, L1
Jiao, Q1
Huang, F1
Han, R1
Zhang, X1
Wang, S1
Wang, W1
Ning, G1
Ren, Z1
Qin, L1
Wang, JQ1
Li, Y1
Li, J1
Zhang, RG1
Shen, T1
Chen, J1
Lin, J1
Liu, R1
Yan, J1
Kuriyan, AE1
Phipps, RP1
O'Loughlin, CW1
Feldon, SE1
Wong, LY1
Diamond, TH1
Lai, A1
Sassi, L1
Compri, E1
Marino, F1
Sivelli, P1
Bijlsma, WR1
Kalmann, R1
Lazarus, JH1
Marcocci, C1
Kahaly, GJ1
Krassas, G1
Wiersinga, WM2
Yoshihara, A1
Yoshimura Noh, J1
Nakachi, A1
Ohye, H1
Sato, S1
Sekiya, K1
Kosuga, Y1
Suzuki, M1
Matsumoto, M1
Kunii, Y1
Watanabe, N1
Mukasa, K1
Inoue, Y1
Ito, K2
Nguyen, NP1
Krafft, SP1
Vos, P1
Vinh-Hung, V1
Ceizyk, M1
Jang, S1
Desai, A1
Abraham, D1
Ewell, L1
Watchman, C1
Hamilton, R1
Jo, BH1
Karlsson, U1
Smith-Raymond, L1
Ewald, N1
Bretzel, RG1
Szanyi, J1
Kremlacek, J1
Kubova, Z1
Langrova, J1
Kuba, M1
Wang, X1
Xu, XL1
Zhao, XL1
Ma, XW1
Yu, H1
Gong, H1
Zhang, SR1
Chen, FL1
WERNER, SC1
EVANS, WH1
OBERDISSE, K1
BROWN, J1
COBURN, JW1
WIGOD, RA1
HISS, JM1
DOWLING, JT1
JOHN, H1
SCHNEIDER, G1
ROPER, A1
Min, HY1
Liu, XP1
Jiang, RX1
Lian, L1
Hu, TS1
Krassas, GE2
Dederichs, B1
Dietlein, M1
Jenniches-Kloth, B1
Schmidt, M1
Theissen, P1
Moka, D1
Schicha, H1
Gogakos, A1
Baldeschi, L1
Lupetti, A1
Vu, P1
Wakelkamp, IM1
Prummel, MF1
Zarkovic, M1
Beleslin, B1
Ciric, J1
Penezic, Z1
Stojkovic, M1
Trbojevic, B1
Drezgic, M1
Savic, S1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Randomized Trial of Intravenous Pulse Versus Sequential Steroid Therapy for Patients With Graves' Orbitopathy[NCT01969019]Phase 470 participants (Anticipated)Interventional2010-01-31Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

3 reviews available for prednisone and Graves Ophthalmopathy

ArticleYear
Comparative Efficacy of Four Treatments in Patients with Graves' Disease: a Network Meta-analysis.
    Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association, 2015, Volume: 123, Issue:5

    Topics: Anti-Inflammatory Agents; Antithyroid Agents; Bayes Theorem; Combined Modality Therapy; Evidence-Bas

2015
Ophthalmic complications in juvenile Graves' Disease - clinic and therapeutic approaches.
    Pediatric endocrinology reviews : PER, 2003, Volume: 1 Suppl 2

    Topics: Adolescent; Anti-Inflammatory Agents, Non-Steroidal; Child; Decision Making; Glucocorticoids; Graves

2003
Thyroid-associated ophthalmopathy in juvenile Graves' disease--clinical, endocrine and therapeutic aspects.
    Journal of pediatric endocrinology & metabolism : JPEM, 2006, Volume: 19, Issue:10

    Topics: Antithyroid Agents; Child; Child, Preschool; Female; Graves Ophthalmopathy; Humans; Male; Octreotide

2006

Trials

2 trials available for prednisone and Graves Ophthalmopathy

ArticleYear
A prospective, randomized trial of intravenous glucocorticoids therapy with different protocols for patients with graves' ophthalmopathy.
    The Journal of clinical endocrinology and metabolism, 2014, Volume: 99, Issue:6

    Topics: Administration, Intravenous; Adult; Aged; Cytokines; Female; Glucocorticoids; Graves Ophthalmopathy;

2014
A pilot study to monitor Graves' ophthalmopathy with a combination of pattern-reversal and motion-onset visual evoked potentials.
    Journal of clinical apheresis, 2012, Volume: 27, Issue:6

    Topics: Administration, Oral; Adult; Blood Component Removal; Combined Modality Therapy; Decompression, Surg

2012

Other Studies

28 other studies available for prednisone and Graves Ophthalmopathy

ArticleYear
Oral steroid prophylaxis for Graves' orbitopathy after radioactive iodine treatment for Graves' disease is not only effective, but also safe.
    Journal of endocrinological investigation, 2020, Volume: 43, Issue:3

    Topics: Administration, Oral; Adult; Aged; Female; Glucocorticoids; Graves Disease; Graves Ophthalmopathy; H

2020
Radioiodine therapy and Graves' disease - Myths and reality.
    PloS one, 2020, Volume: 15, Issue:1

    Topics: Adult; Aged; Anti-Inflammatory Agents; Cigarette Smoking; Female; Graves Disease; Graves Ophthalmopa

2020
REACTIVE AMYLOID A PROTEIN AMYLOIDOSIS IN THE SETTING OF INFECTIVE ENDOCARDITIS MANIFESTING AS BILATERAL ORBITOPATHY AND CHOROIDOPATHY.
    Retinal cases & brief reports, 2022, 11-01, Volume: 16, Issue:6

    Topics: Adult; Amyloid; Amyloidosis; Choroid; Daptomycin; Endocarditis; Female; Graves Ophthalmopathy; Heroi

2022
The influence of Graves' orbitopathy treatment with intravenous glucocorticoids on adrenal function.
    Endokrynologia Polska, 2017, Volume: 68, Issue:4

    Topics: Administration, Intravenous; Adrenal Insufficiency; Adrenocorticotropic Hormone; Adult; Aged; Drug T

2017
Chemotherapy-induced exacerbations of thyroid orbitopathy in a patient with B-cell lymphoma.
    Orbit (Amsterdam, Netherlands), 2018, Volume: 37, Issue:4

    Topics: Administration, Oral; Antibodies, Monoclonal, Murine-Derived; Antineoplastic Combined Chemotherapy P

2018
Combined immunosuppressants and less steroids in active graves' orbitopathy?
    Clinical endocrinology, 2019, Volume: 90, Issue:4

    Topics: Graves Ophthalmopathy; Humans; Immunosuppressive Agents; Prednisone; Randomized Controlled Trials as

2019
Corticosteroids in Moderate-To-Severe Graves' Ophthalmopathy: Oral or Intravenous Therapy?
    International journal of environmental research and public health, 2019, 01-08, Volume: 16, Issue:1

    Topics: Administration, Intravenous; Administration, Oral; Child; Glucocorticoids; Graves Ophthalmopathy; Hu

2019
Diagnostic accuracy of short-time inversion recovery sequence in Graves' Ophthalmopathy before and after prednisone treatment.
    Neuroradiology, 2014, Volume: 56, Issue:5

    Topics: Female; Glucocorticoids; Graves Ophthalmopathy; Humans; Magnetic Resonance Imaging; Male; Middle Age

2014
Concomitant Idiopathic Orbital Inflammatory Pseudotumor and Thyroid-Associated Ophthalmopathy.
    The Journal of craniofacial surgery, 2015, Volume: 26, Issue:6

    Topics: Adult; Anti-Inflammatory Agents; Blepharoptosis; Dexamethasone; Female; Follow-Up Studies; Glucocort

2015
Improvement of thyroid eye disease following treatment with the cyclooxygenase-2 selective inhibitor celecoxib.
    Thyroid : official journal of the American Thyroid Association, 2008, Volume: 18, Issue:8

    Topics: Aged; Celecoxib; Color Perception; Cyclooxygenase 2 Inhibitors; Female; Graves Ophthalmopathy; Human

2008
Severe ophthalmopathy developing after treatment of coexisting malignant struma ovarii and Graves' disease.
    Thyroid : official journal of the American Thyroid Association, 2009, Volume: 19, Issue:10

    Topics: Adult; Anti-Inflammatory Agents; Female; Graves Disease; Graves Ophthalmopathy; Humans; Hyperthyroid

2009
Lower dose prednisone prevents radioiodine-associated exacerbation of initially mild or absent graves' orbitopathy: a retrospective cohort study.
    The Journal of clinical endocrinology and metabolism, 2010, Volume: 95, Issue:3

    Topics: Adult; Aged; Chi-Square Distribution; Female; Glucocorticoids; Graves Disease; Graves Ophthalmopathy

2010
Idiopathic orbital inflammation and Graves ophthalmopathy.
    Archives of ophthalmology (Chicago, Ill. : 1960), 2010, Volume: 128, Issue:1

    Topics: Adult; Autoantibodies; Dacryocystitis; Female; Glucocorticoids; Graves Ophthalmopathy; Humans; Male;

2010
Glucocorticoid administration for Graves' hyperthyroidism treated by radioiodine. A questionnaire survey among members of the European Thyroid Association.
    Journal of endocrinological investigation, 2010, Volume: 33, Issue:6

    Topics: Glucocorticoids; Graves Disease; Graves Ophthalmopathy; Humans; Hyperthyroidism; Iodine Radioisotope

2010
Severe thyroid-associated orbitopathy in Hashimoto's thyroiditis. Report of 2 cases.
    Endocrine journal, 2011, Volume: 58, Issue:5

    Topics: Adult; Female; Graves Ophthalmopathy; Hashimoto Disease; Humans; Magnetic Resonance Imaging; Methylp

2011
Feasibility of tomotherapy for Graves' ophthalmopathy: Dosimetry comparison with conventional radiotherapy.
    Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al], 2011, Volume: 187, Issue:9

    Topics: Adult; Anti-Inflammatory Agents; Drug Resistance; Feasibility Studies; Female; Follow-Up Studies; Gr

2011
[59 year-old man with skin and eye alterations and diabetes mellitus].
    Deutsche medizinische Wochenschrift (1946), 2012, Volume: 137, Issue:19

    Topics: Antithyroid Agents; Carbimazole; Diabetes Mellitus, Type 1; Glucocorticoids; Graves Ophthalmopathy;

2012
Hypoglycemia due to insulin binding antibodies in a patient with insulin-treated type 2 diabetes and Graves' disease.
    Endocrine, 2013, Volume: 43, Issue:1

    Topics: Aged, 80 and over; Antithyroid Agents; Autoantibodies; Autoimmune Diseases; Diabetes Mellitus, Type

2013
Experimentally induced changes in some of the manifestations of infiltrative ophthalmopathy (malignant exophthalmos).
    Transactions of the Association of American Physicians, 1960, Volume: 73

    Topics: Diuretics; Exophthalmos; Graves Ophthalmopathy; Humans; Prednisone

1960
Prednisone therapy in ophthalmic Graves' disease.
    Transactions of the ophthalmological societies of the United Kingdom, 1961, Volume: 81

    Topics: Eye Diseases; Graves Disease; Graves Ophthalmopathy; Humans; Hyperthyroidism; Prednisone

1961
[Isotopes in diagnosis and treatment of endocrine exophthalmos].
    Deutsches medizinisches Journal, 1962, Oct-05, Volume: 13

    Topics: Exophthalmos; Goiter; Graves Disease; Graves Ophthalmopathy; Humans; Hyaluronoglucosaminidase; Iodin

1962
Adrenal steroid therapy of severe infiltrative ophthalmopathy of Graves' disease.
    The American journal of medicine, 1963, Volume: 34

    Topics: Exophthalmos; Goiter; Graves Disease; Graves Ophthalmopathy; Humans; Prednisone

1963
[EXPERIENCES IN THE TREATMENT OF SO-CALLED ENDOCRINE OPHTHALMOPATHY FROM THE VIEWPOINT OF THE INTERNIST].
    Radiobiologia, radiotherapia, 1963, Volume: 4

    Topics: Exophthalmos; Graves Ophthalmopathy; Humans; Hyperthyroidism; Iodine Isotopes; Pituitary Gland; Pred

1963
MPILO HOSPITAL STAFF CLINICAL MEETING. CASE NO. 29-ENDOCRINE EXOPHTHALMOS RESPONDING TO MASSIVE DOSES OF CORTICOSTEROIDS.
    The Central African journal of medicine, 1964, Volume: 10

    Topics: Adrenal Cortex Hormones; Exophthalmos; Glucocorticoids; Graves Ophthalmopathy; Humans; Papilledema;

1964
[Treatment of thyroid-associated ophthalmopathy: comparative study between prednisone and COP therapy].
    [Zhonghua yan ke za zhi] Chinese journal of ophthalmology, 2005, Volume: 41, Issue:9

    Topics: Adult; Aged; Anti-Inflammatory Agents; Cyclophosphamide; Drug Therapy, Combination; Female; Graves O

2005
Radioiodine therapy of Graves' hyperthyroidism in patients without pre-existing ophthalmopathy: can glucocorticoids prevent the development of new ophthalmopathy?
    Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association, 2006, Volume: 114, Issue:7

    Topics: Adult; Female; Follow-Up Studies; Glucocorticoids; Graves Disease; Graves Ophthalmopathy; Humans; Io

2006
Reactivation of Graves' orbitopathy after rehabilitative orbital decompression.
    Ophthalmology, 2007, Volume: 114, Issue:7

    Topics: Aged; Decompression, Surgical; Female; Follow-Up Studies; Glucocorticoids; Graves Ophthalmopathy; Hu

2007
Glucocorticoid effect on insulin sensitivity: a time frame.
    Journal of endocrinological investigation, 2008, Volume: 31, Issue:3

    Topics: Adult; Glucocorticoids; Glucose Clamp Technique; Graves Ophthalmopathy; Humans; Hyperinsulinism; Ins

2008