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prednisone and Glioma

prednisone has been researched along with Glioma in 11 studies

Prednisone: A synthetic anti-inflammatory glucocorticoid derived from CORTISONE. It is biologically inert and converted to PREDNISOLONE in the liver.
prednisone : A synthetic glucocorticoid drug that is particularly effective as an immunosuppressant, and affects virtually all of the immune system. Prednisone is a prodrug that is converted by the liver into prednisolone (a beta-hydroxy group instead of the oxo group at position 11), which is the active drug and also a steroid.

Glioma: Benign and malignant central nervous system neoplasms derived from glial cells (i.e., astrocytes, oligodendrocytes, and ependymocytes). Astrocytes may give rise to astrocytomas (ASTROCYTOMA) or glioblastoma multiforme (see GLIOBLASTOMA). Oligodendrocytes give rise to oligodendrogliomas (OLIGODENDROGLIOMA) and ependymocytes may undergo transformation to become EPENDYMOMA; CHOROID PLEXUS NEOPLASMS; or colloid cysts of the third ventricle. (From Escourolle et al., Manual of Basic Neuropathology, 2nd ed, p21)

Research Excerpts

ExcerptRelevanceReference
"A controlled study of 226 age-matched patients with histologically proven grade 3 and 4 supratentorial gliomas with maximum feasible tumour resection, postoperative Karnofsky performance over 50 and minimum survival of 8 weeks compares the results of supportive care (45 cases), high-dose irradiation of 40 to 66 Gy (59 cases), COMP protocol (CCNU, procarbazine, vincristine, methotrexate, prednisone in 15 day cycles-42 cases) and simultaneous irradiation and COMP chemotherapy (80 cases including 30 survivors)."5.05[Combined treatment of malignant gliomas]. ( Flament, H; Grisold, W; Jellinger, K; Volc, D; Vollmer, R; Weiss, R, 1983)
"Three of 37 adolescents in long-term remission from childhood acute lymphoblastic leukemia (ALL) developed malignant multifocal gliomas several years after completing treatment that included central nervous system (CNS) prophylaxis with radiation (RT) and intrathecal methotrexate (IT-MTX)."3.67Late multifocal gliomas in adolescents previously treated for acute lymphoblastic leukemia. ( Amadori, S; Fontana, M; Mandelli, F; Meloni, G; Pompili, A; Riccio, A; Rubinstein, LJ; Stanton, C, 1987)
"Patients with anaplastic astrocytoma had a median survival of 27 months as compared to 8 months for patients with glioblastoma."2.65Comparison of postoperative radiotherapy and combined postoperative radiotherapy and chemotherapy in the multidisciplinary management of malignant gliomas. A joint Radiation Therapy Oncology Group and Eastern Cooperative Oncology Group study. ( Chang, CH; Horton, J; Kramer, S; Nelson, JS; Perez-Tamayo, R; Salazer, O; Schoenfeld, D; Tsukada, Y; Weinstein, A, 1983)

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19907 (63.64)18.7374
1990's1 (9.09)18.2507
2000's1 (9.09)29.6817
2010's1 (9.09)24.3611
2020's1 (9.09)2.80

Authors

AuthorsStudies
Wiencke, JK1
Molinaro, AM1
Warrier, G1
Rice, T1
Clarke, J1
Taylor, JW1
Wrensch, M1
Hansen, H1
McCoy, L1
Tang, E1
Tamaki, SJ1
Tamaki, CM1
Nissen, E1
Bracci, P1
Salas, LA1
Koestler, DC1
Christensen, BC1
Zhang, Z1
Kelsey, KT1
Meyzer, C1
Dhermain, F1
Ducreux, D1
Habrand, JL1
Varlet, P1
Sainte-Rose, C1
Dufour, C1
Grill, J1
Chang, CH1
Horton, J1
Schoenfeld, D1
Salazer, O1
Perez-Tamayo, R1
Kramer, S1
Weinstein, A1
Nelson, JS1
Tsukada, Y1
Jellinger, K1
Volc, D1
Grisold, W1
Flament, H1
Vollmer, R1
Weiss, R1
Pilichowska, ME1
Schröter, P1
Haug, BA1
Krygier-Stojalowska, A1
Kochi, M1
Ushio, Y1
Seiler, RW1
Gutin, PH1
Takaue, Y1
Sullivan, MP1
Ramirez, I1
Cleary, KR1
van Eys, J2
Baram, TZ1
Cangir, A1
Bruner, JM1
Martinez-Prieto, J1
Fontana, M1
Stanton, C1
Pompili, A1
Amadori, S1
Mandelli, F1
Meloni, G1
Riccio, A1
Rubinstein, LJ1

Reviews

2 reviews available for prednisone and Glioma

ArticleYear
[Chemo-radiotherapy for malignant brain tumors].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2002, Volume: 29, Issue:5

    Topics: Antineoplastic Combined Chemotherapy Protocols; Astrocytoma; Brain Neoplasms; Central Nervous System

2002
Corticosteroid therapy in patients with cerebral tumors: benefits, mechanisms, problems, practicalities.
    Seminars in oncology, 1975, Volume: 2, Issue:1

    Topics: Adrenal Cortex Hormones; Animals; Blood-Brain Barrier; Brain Edema; Brain Neoplasms; Cell Division;

1975

Trials

3 trials available for prednisone and Glioma

ArticleYear
Comparison of postoperative radiotherapy and combined postoperative radiotherapy and chemotherapy in the multidisciplinary management of malignant gliomas. A joint Radiation Therapy Oncology Group and Eastern Cooperative Oncology Group study.
    Cancer, 1983, Sep-15, Volume: 52, Issue:6

    Topics: Adult; Age Factors; Antineoplastic Agents; Astrocytoma; Brain Neoplasms; Carmustine; Clinical Trials

1983
[Combined treatment of malignant gliomas].
    Wiener klinische Wochenschrift, 1983, Jun-10, Volume: 95, Issue:12

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cobalt Radioisotopes; Drug Therapy, Com

1983
Malignant gliomas--ploidy and DNA-content before and after therapy.
    Zentralblatt fur Pathologie, 1994, Volume: 140, Issue:2

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Cyclophosphamide;

1994

Other Studies

6 other studies available for prednisone and Glioma

ArticleYear
DNA methylation as a pharmacodynamic marker of glucocorticoid response and glioma survival.
    Nature communications, 2022, 09-20, Volume: 13, Issue:1

    Topics: Biomarkers; Dexamethasone; DNA Methylation; Glioma; Glucocorticoids; Humans; Maleimides; Prednisone

2022
A case report of pseudoprogression followed by complete remission after proton-beam irradiation for a low-grade glioma in a teenager: the value of dynamic contrast-enhanced MRI.
    Radiation oncology (London, England), 2010, Feb-04, Volume: 5

    Topics: Adolescent; Anti-Inflammatory Agents; Brain Neoplasms; Child; Contrast Media; Glioma; Humans; Image

2010
Delayed response to brain tumor chemotherapy.
    Surgical neurology, 1979, Volume: 11, Issue:2

    Topics: Adult; Brain Neoplasms; Glioma; Humans; Lomustine; Male; Middle Aged; Nitrosourea Compounds; Prednis

1979
Second malignant neoplasm in treated Hodgkin's disease. Report of a patient and scope of the problem.
    American journal of diseases of children (1960), 1986, Volume: 140, Issue:1

    Topics: Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Child; Combined Modality Therapy; G

1986
Salvage chemotherapy for recurrent primary brain tumors in children.
    The Journal of pediatrics, 1988, Volume: 113, Issue:3

    Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Astrocytoma; Brain Neoplasms; Child; Chi

1988
Late multifocal gliomas in adolescents previously treated for acute lymphoblastic leukemia.
    Cancer, 1987, Oct-01, Volume: 60, Issue:7

    Topics: Adolescent; Brain Neoplasms; Female; Glial Fibrillary Acidic Protein; Glioma; Humans; Injections, Sp

1987