Page last updated: 2024-11-07

prednisone and Genetic Predisposition

prednisone has been researched along with Genetic Predisposition in 51 studies

Prednisone: A synthetic anti-inflammatory glucocorticoid derived from CORTISONE. It is biologically inert and converted to PREDNISOLONE in the liver.
prednisone : A synthetic glucocorticoid drug that is particularly effective as an immunosuppressant, and affects virtually all of the immune system. Prednisone is a prodrug that is converted by the liver into prednisolone (a beta-hydroxy group instead of the oxo group at position 11), which is the active drug and also a steroid.

Research Excerpts

ExcerptRelevanceReference
"While combination of rituximab, cyclophosphamide, doxorubicin, vincristine and prednisone (R-CHOP) cures most patients with diffuse large B-cell lymphoma (DLBCL), those with high-risk international prognostic index disease have inferior survival."9.34ENGINE: a Phase III randomized placebo controlled study of enzastaurin/R-CHOP as frontline therapy in high-risk diffuse large B-cell lymphoma patients with the genomic biomarker DGM1. ( Brody, J; Cao, J; Han, I; Heineman, T; Jing, H; Jivani, M; Lansigan, F; Li, L; Liu, Y; Lue, JK; Luo, W; Maly, J; Nowakowski, GS; Rizvi, S; Smith, SD; Song, Y; Sun, J; Sun, X; Zhang, L; Zhang, Q; Zhu, J, 2020)
"While combination of rituximab, cyclophosphamide, doxorubicin, vincristine and prednisone (R-CHOP) cures most patients with diffuse large B-cell lymphoma (DLBCL), those with high-risk international prognostic index disease have inferior survival."5.34ENGINE: a Phase III randomized placebo controlled study of enzastaurin/R-CHOP as frontline therapy in high-risk diffuse large B-cell lymphoma patients with the genomic biomarker DGM1. ( Brody, J; Cao, J; Han, I; Heineman, T; Jing, H; Jivani, M; Lansigan, F; Li, L; Liu, Y; Lue, JK; Luo, W; Maly, J; Nowakowski, GS; Rizvi, S; Smith, SD; Song, Y; Sun, J; Sun, X; Zhang, L; Zhang, Q; Zhu, J, 2020)
"We first performed a gene-by-OCS interaction genome-wide association study (GWAS) of BMA in 489 white participants in the Childhood Asthma Management Program trial who took short-term oral prednisone bursts when they experienced acute asthma exacerbations."5.20Genetic risk factors for decreased bone mineral accretion in children with asthma receiving multiple oral corticosteroid bursts. ( Ge, B; Grundberg, E; Kelly, HW; Park, HW; Pastinen, T; Tantisira, KG; Tse, S, 2015)
" We also conducted a dose-response meta-analysis to analyze the cumulative dosage and SONFH risk in mutation carriers."2.61Association between genetic polymorphisms and osteonecrosis in steroid treatment populations: a detailed stratified and dose-response meta-analysis. ( Jing, M; Yang, J; Yang, X, 2019)
" In order to reduce the ocular side effects of the GCs there are some advisements, including a complete history, regular examination, GC should be prescribed in minimal dosage and minimal course, and as possible GC-sparing drugs should always be considered."2.53Early onset steroid induced posterior subcapsular cataract in a patient with common variable immunodeficiency: case reports and review of literature. ( Abolhassani, H; Aghamohammadi, A; Azizi, G; Ghareje Daghi, M; Marefat, H, 2016)
"Autoimmune hepatitis is a chronic inflammatory disease of the liver with a dismal prognosis when left untreated."2.46Autoimmune hepatitis. ( Strassburg, CP, 2010)
"Autoimmune hepatitis has a global distribution and affects all ages."2.41Current concepts in the diagnosis, pathogenesis, and treatment of autoimmune hepatitis. ( Al-Khalidi, JA; Czaja, AJ, 2001)
"Prednisone was used to treat IPF patients."1.42MMP-9 1562C>T Gene Polymorphism and Efficacy of Glucocorticoid Therapy in Idiopathic Pulmonary Fibrosis Patients. ( Fang, SC; Wang, C; Wang, CY; Wang, W; Wu, J; Xu, B; Zhang, HT; Zhang, YM, 2015)
"Finally, a genomic instability gene signature was highlighted in gene expression profiles of patients belonging to the high-risk GERS-defined group."1.38Gene expression-based risk score in diffuse large B-cell lymphoma. ( Bret, C; Klein, B; Moreaux, J, 2012)
"To determine the genetic susceptibility of rats to develop GC-induced femoral head ON, we evaluated 5 different inbred strains of rats (Spontaneous Hypertensive Rat, Wistar Kyoto, Wistar Furth, SASCO Fisher and Lewis)."1.37A rat model of early stage osteonecrosis induced by glucocorticoids. ( Chow, TY; Cournoyer, D; Harvey, EJ; Kerachian, MA; Nahal, A; Séguin, C, 2011)
"Methotrexate is a key drug in acute lymphoblastic leukemia (ALL) treatment; it inhibits DNA replication by blocking the conversion of 5,10 methylene tetrahydrofolate to 5-methylene tetrahydrofolate by methylene tetrahydrofolate reductase (MTHFR)."1.36Methylene tetrahydrofolate reductase gene polymorphism in Egyptian children with acute lymphoblastic leukemia. ( Abdulghaffar, EE; Abou El Asrar, M; Adly, AA; El-Bostany, EA; El-Ghouroury, EA; Tantawy, AA, 2010)
"Susceptibility to Graves' disease (GD) is determined by multiple environmental and genetic factors, which are not fully understood."1.32Development of Graves' disease in a patient under immunosuppressive therapy after liver transplantation. ( Bednarczuk, T; Makowska, U; Nauman, J, 2003)
"Genetic susceptibility to type 1 autoimmune hepatitis is indicated by a preponderance of female subjects and strong associations with human leukocyte antigens (HLA) DRB1*0301 and DRB1*0401."1.31Cytotoxic T lymphocyte antigen-4 (CTLA-4) gene polymorphisms and susceptibility to type 1 autoimmune hepatitis. ( Agarwal, K; Czaja, AJ; Donaldson, PT; Jones, DE, 2000)

Research

Studies (51)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's17 (33.33)29.6817
2010's30 (58.82)24.3611
2020's4 (7.84)2.80

Authors

AuthorsStudies
Dlouhy, I1
Karube, K1
Enjuanes, A1
Salaverria, I1
Nadeu, F1
Ramis-Zaldivar, JE1
Valero, JG1
Rivas-Delgado, A1
Magnano, L1
Martin-García, D1
Pérez-Galán, P1
Clot, G1
Rovira, J1
Jares, P1
Balagué, O1
Giné, E1
Mozas, P1
Briones, J1
Sancho, JM1
Salar, A1
Mercadal, S1
Alcoceba, M1
Valera, A1
Campo, E1
López-Guillermo, A1
Rausch, CR1
Jabbour, EJ1
Kantarjian, HM1
Kadia, TM1
Marangon, AV1
Colli, CM1
Cardozo, DM1
Visentainer, JEL1
Sell, AM1
Guimaraes, F1
Marques, SBD1
Lieber, SR1
Aranha, FJP1
Zulli, R1
de Souza, VH1
de Souza, CA1
Nowakowski, GS1
Zhu, J1
Zhang, Q1
Brody, J1
Sun, X1
Maly, J1
Song, Y2
Rizvi, S1
Lansigan, F1
Jing, H1
Cao, J1
Lue, JK1
Luo, W1
Zhang, L1
Li, L1
Han, I1
Sun, J1
Jivani, M1
Liu, Y1
Heineman, T1
Smith, SD1
Haraguchi, M1
Harada, N1
Watanabe, J1
Yoshikawa, H1
Shirai, Y1
Komura, M1
Koyama, M1
Ito, J1
Tsukune, Y1
Horimoto, Y1
Hayashi, T1
Nagaoka, T1
Uekusa, T1
Takahashi, K1
Rooney, JP1
Ryan, N1
Chorley, BN1
Hester, SD1
Kenyon, EM1
Schmid, JE1
George, BJ1
Hughes, MF1
Sey, YM1
Tennant, A1
MacMillan, DK1
Simmons, JE1
McQueen, CA1
Pandiri, A1
Wood, CE1
Corton, JC1
Tantawy, AAG1
Ebeid, FSE1
Adly, AAM1
El-Ghoroury, E1
Mostafa, M1
Hu, S1
Zuo, X1
Li, Y1
Yang, J1
Jing, M1
Yang, X1
Bret, C1
Klein, B1
Moreaux, J1
Tarabar, O1
Cikota-Aleksić, B1
Tukić, L1
Milanović, N1
Aleksić, A1
Magić, Z1
Zhang, Y2
Chen, MB1
Zhou, XY1
Hong, XN1
Yu, G1
Gao, Z1
Huang, X1
Park, HW1
Ge, B1
Tse, S1
Grundberg, E1
Pastinen, T1
Kelly, HW1
Tantisira, KG1
Alexander, MP1
Fervenza, FC1
De Vriese, AS1
Smith, RJH1
Nasr, SH1
Cornell, LD1
Herrera Hernandez, LP1
Sethi, S1
Zhang, HT1
Fang, SC1
Wang, CY1
Wang, W1
Wu, J1
Wang, C1
Xu, B1
Zhang, YM1
Yazdani, N1
Kakavand Hamidi, A1
Ghazavi, H1
Rikhtegar, MJ1
Motesadi Zarandi, M1
Qorbani, M1
Amoli, MM1
Hertz, DL1
Owzar, K1
Lessans, S1
Wing, C1
Jiang, C1
Kelly, WK1
Patel, J1
Halabi, S1
Furukawa, Y1
Wheeler, HE1
Sibley, AB1
Lassiter, C1
Weisman, L1
Watson, D1
Krens, SD1
Mulkey, F1
Renn, CL1
Small, EJ1
Febbo, PG1
Shterev, I1
Kroetz, DL1
Friedman, PN1
Mahoney, JF1
Carducci, MA1
Kelley, MJ1
Nakamura, Y1
Kubo, M1
Dorsey, SG1
Dolan, ME1
Morris, MJ1
Ratain, MJ1
McLeod, HL1
Han, M1
Murugesan, A1
Bahlis, NJ1
Song, K1
White, D1
Chen, C1
Seftel, MD1
Howsen-Jan, K1
Reece, D1
Stewart, K1
Xie, Y1
Hay, AE1
Shepherd, L1
Djurfeldt, M1
Zhu, L1
Meyer, RM1
Chen, BE1
Reiman, T1
de Mendonça, GR1
Brito, AB1
Rocha, RM1
Delamain, MT1
de Andrade Natal, R1
Soares, FA1
Colleoni, GW1
Souza, CA1
Vassallo, J1
Lima, CS1
Marefat, H1
Abolhassani, H1
Ghareje Daghi, M1
Azizi, G1
Aghamohammadi, A1
Karmali, R1
Gordon, LI1
Tantawy, AA1
El-Bostany, EA1
Adly, AA1
Abou El Asrar, M1
El-Ghouroury, EA1
Abdulghaffar, EE1
Mahadeo, KM1
Dhall, G1
Panigrahy, A1
Lastra, C1
Ettinger, LJ1
Palomino-Morales, RJ1
Vazquez-Rodriguez, TR1
Torres, O1
Morado, IC1
Castañeda, S1
Miranda-Filloy, JA1
Callejas-Rubio, JL1
Fernandez-Gutierrez, B1
Gonzalez-Gay, MA1
Martin, J1
Wolfe, KC1
Poma, R1
Strassburg, CP1
Morabito, F1
Hohaus, S1
Mammi, C1
Marcheselli, L1
Gentile, M1
Merli, F1
Montanini, A1
Stelitano, C1
La Sala, A1
Scalone, R1
Voso, MT1
Luminari, S1
Iannitto, E1
Gobbi, P1
Federico, M1
Krupoves, A1
Mack, D1
Seidman, E1
Deslandres, C1
Amre, D1
D'Agati, VD1
Kaskel, FJ1
Falk, RJ1
Kerachian, MA1
Harvey, EJ1
Cournoyer, D1
Chow, TY1
Nahal, A1
Séguin, C1
Moritake, H1
Yamada, A1
Kimoto, Y1
Sawa, D1
Shimonodan, H1
Nunoi, H1
Vajro, P1
Paolella, G1
Brackmann, F1
Dörr, HG1
Bartram, CR1
Hinderhofer, K1
Holter, W1
Langer, T1
Lauten, M1
Matthias, T1
Stanulla, M1
Beger, C1
Welte, K1
Schrappe, M1
Fabris, M1
Tolusso, B1
Di Poi, E1
Assaloni, R1
Sinigaglia, L1
Ferraccioli, G1
Fries, JF1
Wolfe, F1
Apple, R1
Erlich, H1
Bugawan, T1
Holmes, T1
Bruce, B1
Hedayati, SS1
Reddan, DN1
Szczech, LA1
Bednarczuk, T1
Makowska, U1
Nauman, J1
Mohren, M1
Essbach, U1
Franke, A1
Klink, A1
Maas, C1
Markmann, I1
Pelz, AF1
Jentsch-Ullrich, K1
Pawlik, A1
Czerny, B1
Dabrowska-Zamojcin, E1
Górnik, W1
Poziomkowska, I1
Gawrońska-Szklarz, B1
Herczyńska, M1
Naithani, R1
Chandra, J1
Kumar, A1
Choudhary, SR1
Sharma, S1
Zein, EF1
Karaa, SE1
Megarbane, A1
Agarwal, K1
Czaja, AJ2
Jones, DE1
Donaldson, PT1
Peschken, CA1
Esdaile, JM1
Lange, B1
Jabali, Y1
Starý, J1
Hak, J1
Blazek, B1
Hrstkova, H1
Mihál, V1
Mydlil, J1
Timr, P1
Gajdos, P1
Yeo, SW2
Chang, KH1
Suh, BD2
Kim, TG2
Han, H2
Silfen, ME1
Garvin, JH1
Hays, AP1
Starkman, HS1
Aranoff, GS1
Levine, LS1
Feldstein, NA1
Wong, B1
Oberfield, SE1
Park, SN1
Park, YS1
Choi, HB1
Al-Khalidi, JA1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Randomized Phase 3 Study to Evaluate the Efficacy and Safety of Enzastaurin Plus R-CHOP Versus R-CHOP in Treatment-Naive Subjects With High-Risk Diffuse Large B-Cell Lymphoma Who Possess the Novel Genomic Biomarker DGM1™[NCT03263026]Phase 3256 participants (Actual)Interventional2018-03-20Completed
Predictors of Disease Progression in Patients With Primary Focal Segmental Glomerulosclerosis[NCT03126201]86 participants (Actual)Observational2016-12-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

9 reviews available for prednisone and Genetic Predisposition

ArticleYear
Coexistence of systemic sclerosis and ankylosing spondylitis: A case report and literature review.
    Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences, 2018, Nov-28, Volume: 43, Issue:11

    Topics: Anti-Inflammatory Agents; Creatine Kinase; Cyclophosphamide; Genetic Predisposition to Disease; Hist

2018
Association between genetic polymorphisms and osteonecrosis in steroid treatment populations: a detailed stratified and dose-response meta-analysis.
    Bioscience reports, 2019, 05-31, Volume: 39, Issue:5

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Apolipoproteins B; ATP Binding Cassette Transporter, Sub

2019
Early onset steroid induced posterior subcapsular cataract in a patient with common variable immunodeficiency: case reports and review of literature.
    European annals of allergy and clinical immunology, 2016, Volume: 48, Issue:5

    Topics: Adolescent; Cataract; Common Variable Immunodeficiency; DNA Mutational Analysis; Genetic Predisposit

2016
Molecular Subtyping in Diffuse Large B Cell Lymphoma: Closer to an Approach of Precision Therapy.
    Current treatment options in oncology, 2017, Volume: 18, Issue:2

    Topics: Antibodies, Monoclonal, Murine-Derived; Antineoplastic Combined Chemotherapy Protocols; Biomarkers;

2017
Autoimmune hepatitis.
    Best practice & research. Clinical gastroenterology, 2010, Volume: 24, Issue:5

    Topics: Animals; Azathioprine; Budesonide; Diagnosis, Differential; Drug Therapy, Combination; Genetic Predi

2010
Focal segmental glomerulosclerosis.
    The New England journal of medicine, 2011, Dec-22, Volume: 365, Issue:25

    Topics: Adult; Algorithms; Biopsy; Child; Genetic Predisposition to Disease; Glomerulosclerosis, Focal Segme

2011
HIV-associated nephropathy: a review of the epidemiology and clinical course in the HAART era.
    AIDS patient care and STDs, 2003, Volume: 17, Issue:2

    Topics: Adult; AIDS-Associated Nephropathy; Angiotensin-Converting Enzyme Inhibitors; Antiretroviral Therapy

2003
The management of neoplastic disorders of haematopoiesis in children with Down's syndrome.
    British journal of haematology, 2000, Volume: 110, Issue:3

    Topics: Acute Disease; Adolescent; Adult; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemother

2000
Current concepts in the diagnosis, pathogenesis, and treatment of autoimmune hepatitis.
    Mayo Clinic proceedings, 2001, Volume: 76, Issue:12

    Topics: Age Distribution; Anti-Inflammatory Agents; Azathioprine; Causality; Drug Therapy, Combination; Euro

2001

Trials

5 trials available for prednisone and Genetic Predisposition

ArticleYear
ENGINE: a Phase III randomized placebo controlled study of enzastaurin/R-CHOP as frontline therapy in high-risk diffuse large B-cell lymphoma patients with the genomic biomarker DGM1.
    Future oncology (London, England), 2020, Volume: 16, Issue:15

    Topics: Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Cyclophosphamide; Doxorubicin; Fe

2020
Genetic risk factors for decreased bone mineral accretion in children with asthma receiving multiple oral corticosteroid bursts.
    The Journal of allergy and clinical immunology, 2015, Volume: 136, Issue:5

    Topics: Administration, Oral; Adrenal Cortex Hormones; Asthma; Bone Density; Bone Development; Bone Diseases

2015
Pharmacogenetic Discovery in CALGB (Alliance) 90401 and Mechanistic Validation of a VAC14 Polymorphism that Increases Risk of Docetaxel-Induced Neuropathy.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2016, Oct-01, Volume: 22, Issue:19

    Topics: Adult; Aged; Aged, 80 and over; Animals; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab

2016
Role of glutathione-S-transferase (GST) polymorphisms in patients with advanced Hodgkin lymphoma: results from the HD2000 GISL trial.
    Leukemia & lymphoma, 2012, Volume: 53, Issue:3

    Topics: Adult; Anemia; Antineoplastic Combined Chemotherapy Protocols; Biotransformation; Bleomycin; Carbopl

2012
[The influence of IL-6 polymorphism on efficacy of treatment of rheumatoid arthritis patients with methotrexate and prednisone].
    Polskie Archiwum Medycyny Wewnetrznej, 2005, Volume: 114, Issue:3

    Topics: Adult; Aged; Antirheumatic Agents; Arthritis, Rheumatoid; Female; Genetic Predisposition to Disease;

2005

Other Studies

37 other studies available for prednisone and Genetic Predisposition

ArticleYear
Revised International Prognostic Index and genetic alterations are associated with early failure to R-CHOP in patients with diffuse large B-cell lymphoma.
    British journal of haematology, 2022, Volume: 196, Issue:3

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Biopsy; Cyclophospha

2022
Optimizing the use of the hyperCVAD regimen: Clinical vignettes and practical management.
    Cancer, 2020, 03-15, Volume: 126, Issue:6

    Topics: Age Factors; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Brai

2020
Impact of SNPs/Haplotypes of
    Journal of immunology research, 2019, Volume: 2019

    Topics: Aged; Alleles; Antineoplastic Combined Chemotherapy Protocols; Case-Control Studies; Cyclophosphamid

2019
Disseminated nontuberculous mycobacteriosis and fungemia after second delivery in a patient with MonoMAC syndrome/GATA2 mutation: a case report.
    BMC infectious diseases, 2021, May-29, Volume: 21, Issue:1

    Topics: Adult; Anti-Bacterial Agents; Fatal Outcome; Female; Fungemia; GATA2 Deficiency; GATA2 Transcription

2021
From the Cover: Genomic Effects of Androstenedione and Sex-Specific Liver Cancer Susceptibility in Mice.
    Toxicological sciences : an official journal of the Society of Toxicology, 2017, Nov-01, Volume: 160, Issue:1

    Topics: Androstenedione; Animals; Biomarkers, Tumor; Cell Proliferation; Cell Transformation, Neoplastic; Cy

2017
Influence of thiopurine methyltransferase gene polymorphism on Egyptian children with acute lymphoblastic leukaemia.
    Journal of genetics, 2017, Volume: 96, Issue:6

    Topics: Adolescent; Alleles; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Child; Child, Pre

2017
Gene expression-based risk score in diffuse large B-cell lymphoma.
    Oncotarget, 2012, Volume: 3, Issue:12

    Topics: Antibodies, Monoclonal, Murine-Derived; Antineoplastic Combined Chemotherapy Protocols; Biomarkers,

2012
Association of interleukin-10, tumor necrosis factor-α and transforming growth factor-β gene polymorphisms with the outcome of diffuse large B-cell lymphomas.
    International journal of clinical oncology, 2014, Volume: 19, Issue:1

    Topics: Aged; Antibodies, Monoclonal, Murine-Derived; Antineoplastic Combined Chemotherapy Protocols; Biomar

2014
Lymphotoxin alpha (LTA) polymorphism is associated with prognosis of non-Hodgkin's lymphoma in a Chinese population.
    PloS one, 2013, Volume: 8, Issue:6

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Apoptosis Regulatory Protei

2013
ALK-positive anaplastic large cell lymphoma with an unusual alveolar growth pattern.
    International journal of clinical and experimental pathology, 2014, Volume: 7, Issue:12

    Topics: Anaplastic Lymphoma Kinase; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Biops

2014
C3 glomerulonephritis and autoimmune disease: more than a fortuitous association?
    Journal of nephrology, 2016, Volume: 29, Issue:2

    Topics: Adult; Autoimmune Diseases; Autoimmunity; Biomarkers; Complement Activation; Complement C3; Compleme

2016
MMP-9 1562C>T Gene Polymorphism and Efficacy of Glucocorticoid Therapy in Idiopathic Pulmonary Fibrosis Patients.
    Genetic testing and molecular biomarkers, 2015, Volume: 19, Issue:11

    Topics: Aged; Alleles; Case-Control Studies; Female; Gene Frequency; Genetic Predisposition to Disease; Gluc

2015
Association between Macrophage Migration Inhibitory Factor Gene Variation and Response to Glucocorticoid Treatment in Sudden Sensorineural Hearing Loss.
    Audiology & neuro-otology, 2015, Volume: 20, Issue:6

    Topics: Adult; Case-Control Studies; Dexamethasone; Female; Gene Frequency; Genetic Predisposition to Diseas

2015
A pharmacogenetic analysis of the Canadian Cancer Trials Group MY.10 clinical trial of maintenance therapy for multiple myeloma.
    Blood, 2016, 08-04, Volume: 128, Issue:5

    Topics: Antineoplastic Combined Chemotherapy Protocols; Canada; Genetic Predisposition to Disease; Hematopoi

2016
Association of VEGFA-2578 C>A polymorphism with clinicopathological aspects and outcome in follicular lymphoma patients.
    Blood cancer journal, 2016, 08-26, Volume: 6, Issue:8

    Topics: Adult; Antibodies, Monoclonal, Murine-Derived; Antineoplastic Combined Chemotherapy Protocols; Case-

2016
Methylene tetrahydrofolate reductase gene polymorphism in Egyptian children with acute lymphoblastic leukemia.
    Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis, 2010, Volume: 21, Issue:1

    Topics: Alleles; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Chemical and Drug Induced Liv

2010
Subacute methotrexate neurotoxicity and cerebral venous sinus thrombosis in a 12-year-old with acute lymphoblastic leukemia and methylenetetrahydrofolate reductase (MTHFR) C677T polymorphism: homocysteine-mediated methotrexate neurotoxicity via direct end
    Pediatric hematology and oncology, 2010, Volume: 27, Issue:1

    Topics: Amino Acid Substitution; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Child; Cytara

2010
Association between IL-18 gene polymorphisms and biopsy-proven giant cell arteritis.
    Arthritis research & therapy, 2010, Volume: 12, Issue:2

    Topics: Biopsy; Drug Therapy, Combination; Genetic Predisposition to Disease; Genotype; Giant Cell Arteritis

2010
Syringomyelia in the Cavalier King Charles spaniel (CKCS) dog.
    The Canadian veterinary journal = La revue veterinaire canadienne, 2010, Volume: 51, Issue:1

    Topics: Amines; Analgesics; Animals; Anti-Inflammatory Agents; Arnold-Chiari Malformation; Breeding; Cyclohe

2010
Associations between variants in the ABCB1 (MDR1) gene and corticosteroid dependence in children with Crohn's disease.
    Inflammatory bowel diseases, 2011, Volume: 17, Issue:11

    Topics: Adolescent; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfami

2011
A rat model of early stage osteonecrosis induced by glucocorticoids.
    Journal of orthopaedic surgery and research, 2011, Dec-21, Volume: 6

    Topics: Animals; Apoptosis; Disease Models, Animal; Drug Implants; Female; Femur Head Necrosis; Genetic Pred

2011
Acute megakaryoblastic leukemia and severe pulmonary fibrosis in a child with Down syndrome: successful treatment with ultra low-dose cytarabine using GATA1 mutation to monitor minimal residual disease.
    American journal of hematology, 2012, Volume: 87, Issue:4

    Topics: Antimetabolites, Antineoplastic; Biomarkers; Biomarkers, Tumor; Cytarabine; Cytokines; Disease Progr

2012
Autoimmune hepatitis: current knowledge.
    Clinics and research in hepatology and gastroenterology, 2012, Volume: 36, Issue:3

    Topics: Antibodies, Antinuclear; Autoantibodies; Autoantigens; Azathioprine; Child; Cyclosporine; Genetic Pr

2012
Glucocorticoid withdrawal - heterozygous carriers of congenital adrenal hyperplasia at risk?
    Klinische Padiatrie, 2012, Volume: 224, Issue:6

    Topics: Adrenal Hyperplasia, Congenital; Adrenocorticotropic Hormone; Adrenogenital Syndrome; Antineoplastic

2012
Association of initial response to prednisone treatment in childhood acute lymphoblastic leukaemia and polymorphisms within the tumour necrosis factor and the interleukin-10 genes.
    Leukemia, 2002, Volume: 16, Issue:8

    Topics: Adolescent; Alleles; Antineoplastic Combined Chemotherapy Protocols; Case-Control Studies; Child; Ch

2002
Tumor necrosis factor-alpha receptor II polymorphism in patients from southern Europe with mild-moderate and severe rheumatoid arthritis.
    The Journal of rheumatology, 2002, Volume: 29, Issue:9

    Topics: Adult; Age Distribution; Aged; Aged, 80 and over; Antigens, CD; Arthritis, Rheumatoid; Case-Control

2002
HLA-DRB1 genotype associations in 793 white patients from a rheumatoid arthritis inception cohort: frequency, severity, and treatment bias.
    Arthritis and rheumatism, 2002, Volume: 46, Issue:9

    Topics: Alleles; Anti-Inflammatory Agents; Antirheumatic Agents; Arthritis, Rheumatoid; Cohort Studies; Epit

2002
Development of Graves' disease in a patient under immunosuppressive therapy after liver transplantation.
    Journal of endocrinological investigation, 2003, Volume: 26, Issue:3

    Topics: Adolescent; Alleles; Cyclosporine; Genetic Predisposition to Disease; Graves Disease; HLA-DR Antigen

2003
Acute myelofibrosis in a patient with diffuse large cell non Hodgkin's lymphoma and renal cancer.
    Leukemia & lymphoma, 2003, Volume: 44, Issue:9

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Carcinoma, Renal Cell; Chromosome Aberr

2003
Simultaneous occurrence of Wilms tumor and Burkitt lymphoma in two brothers.
    Pediatric blood & cancer, 2007, Volume: 49, Issue:6

    Topics: Antineoplastic Combined Chemotherapy Protocols; Burkitt Lymphoma; Child, Preschool; Cyclophosphamide

2007
Familial occurrence of painful subacute thyroiditis associated with human leukocyte antigen-B35.
    Presse medicale (Paris, France : 1983), 2007, Volume: 36, Issue:5 Pt 1

    Topics: Administration, Oral; Adrenergic beta-Antagonists; Adult; Anti-Inflammatory Agents; Anti-Inflammator

2007
Cytotoxic T lymphocyte antigen-4 (CTLA-4) gene polymorphisms and susceptibility to type 1 autoimmune hepatitis.
    Hepatology (Baltimore, Md.), 2000, Volume: 31, Issue:1

    Topics: Abatacept; Adolescent; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents; Antigens, CD; Antig

2000
Systemic lupus erythematosus in North American Indians: a population based study.
    The Journal of rheumatology, 2000, Volume: 27, Issue:8

    Topics: Adult; Age Distribution; Anti-Inflammatory Agents; Autoantibodies; Female; Genetic Predisposition to

2000
Acute lymphoblastic leukemia in infants: a decade of experience in the Czech Republic.
    Medical and pediatric oncology, 2000, Volume: 35, Issue:5

    Topics: Analysis of Variance; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Chromosomes, Hum

2000
Distribution of HLA-A, -B and -DRB1 alleles in patients with sudden sensorineural hearing loss.
    Acta oto-laryngologica, 2000, Volume: 120, Issue:6

    Topics: Adult; Aged; Anti-Inflammatory Agents; Audiometry, Pure-Tone; Female; Gene Frequency; Genetic Predis

2000
Primary central nervous system lymphoma in childhood presenting as progressive panhypopituitarism.
    Journal of pediatric hematology/oncology, 2001, Volume: 23, Issue:2

    Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Burkitt Lymphoma; Cyclophosphamide; Cyta

2001
Different distribution of HLA class II alleles according to response to corticosteroid therapy in sudden sensorineural hearing loss.
    Archives of otolaryngology--head & neck surgery, 2001, Volume: 127, Issue:8

    Topics: Alleles; Female; Gene Frequency; Genetic Predisposition to Disease; Genotype; Glucocorticoids; Haplo

2001