Page last updated: 2024-11-07

prednisone and Fetal Growth Restriction

prednisone has been researched along with Fetal Growth Restriction in 19 studies

Prednisone: A synthetic anti-inflammatory glucocorticoid derived from CORTISONE. It is biologically inert and converted to PREDNISOLONE in the liver.
prednisone : A synthetic glucocorticoid drug that is particularly effective as an immunosuppressant, and affects virtually all of the immune system. Prednisone is a prodrug that is converted by the liver into prednisolone (a beta-hydroxy group instead of the oxo group at position 11), which is the active drug and also a steroid.

Research Excerpts

ExcerptRelevanceReference
"The better pregnancy outcome associated with lower prednisone dosage is probably related to the fact that the patients selected to receive the low-dose regimen have had a longer and less complicated post-transplantation course."7.69Prednisone dosage and pregnancy outcome in renal allograft recipients. ( Bar, J; Boner, G; Fisch, B; Gelerenter, I; Hod, M; Wittenberg, C, 1997)
"Treatment with prednisone and aspirin appears to be efficacious, safe, and economic in the prevention of pregnancy loss and fetal growth retardation in patients with aCL."7.68Prevention of anticardiolipin antibody-related pregnancy losses with prednisone and aspirin. ( Angel, J; Espinoza, LR; Hubble, CL; Jara, LJ; Martínez-Osuna, P; O'Brien, W; Saway, S; Seleznick, MJ; Silveira, LH, 1992)
"(1) Those patients with unstable status progestation, patients being newly diagnosed with SLE during pregnancy or patients irregularly using prednisone became active during pregnancy."3.73[Influential factors of systemic lupus erythematosus activity during pregnancy and its relationship with pregnancy outcome]. ( Tan, JP; Wang, YH; Wu, XX; Zhang, JP, 2006)
"The better pregnancy outcome associated with lower prednisone dosage is probably related to the fact that the patients selected to receive the low-dose regimen have had a longer and less complicated post-transplantation course."3.69Prednisone dosage and pregnancy outcome in renal allograft recipients. ( Bar, J; Boner, G; Fisch, B; Gelerenter, I; Hod, M; Wittenberg, C, 1997)
"Treatment with prednisone and aspirin appears to be efficacious, safe, and economic in the prevention of pregnancy loss and fetal growth retardation in patients with aCL."3.68Prevention of anticardiolipin antibody-related pregnancy losses with prednisone and aspirin. ( Angel, J; Espinoza, LR; Hubble, CL; Jara, LJ; Martínez-Osuna, P; O'Brien, W; Saway, S; Seleznick, MJ; Silveira, LH, 1992)
" During their next pregnancy, the patients were treated with 40 to 50 mg of prednisone per day and 81 mg of aspirin per day."3.67Obstetric complications associated with the lupus anticoagulant. ( Branch, DW; Hershgold, E; Kochenour, NK; Scott, JR, 1985)
"The risk of preeclampsia and placental insufficiency was substantial and occurred in 50% of patients."2.42Antiphospholipid syndrome in obstetrics. ( Heilmann, L; Pollow, K; von Tempelhoff, GF, 2003)
"Takayasu's arteritis is a chronic and non-specific disease of young women in reproductive age that primarily affects the aorta, its branches and the pulmonary artery."1.37[Takayasu's arteritis in pregnancy: report seven cases]. ( Carvajal-Valencia, JA; Chacón-Solís, AR; Estrada-Altamirano, A; Hernández-Pacheco, JA; Maya-Quiñones, JL; Valenzuela-Jirón, A, 2011)
"In 40 to 50% of DBA patients, congenital abnormalities mostly in the cephalic area and in thumbs and upper limbs have been described."1.36Diamond-Blackfan anemia, ribosome and erythropoiesis. ( Da Costa, L; Leblanc, T; Mohandas, N; Moniz, H; Simansour, M; Tchernia, G, 2010)
"Mean birth weight was 2."1.28[Pregnancy after renal transplantation. 27 patients and review of the literature]. ( Edouard, D; Fernandez, H; Frydman, R; Ville, Y, 1992)
"Polymyositis is a myositic disease that is rarely seen as a complicating condition of pregnancy."1.27Polymyositis in pregnancy. A case report and literature review. ( Gast, MJ; Houck, W; Melnyk, C, 1987)

Research

Studies (19)

TimeframeStudies, this research(%)All Research%
pre-19906 (31.58)18.7374
1990's7 (36.84)18.2507
2000's3 (15.79)29.6817
2010's3 (15.79)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Leroux, M1
Desveaux, C1
Parcevaux, M1
Julliac, B1
Gouyon, JB1
Dallay, D1
Pellegrin, JL1
Boukerrou, M1
Blanco, P1
Lazaro, E1
Da Costa, L1
Moniz, H1
Simansour, M1
Tchernia, G1
Mohandas, N1
Leblanc, T1
Hernández-Pacheco, JA1
Estrada-Altamirano, A1
Valenzuela-Jirón, A1
Maya-Quiñones, JL1
Carvajal-Valencia, JA1
Chacón-Solís, AR1
Heilmann, L1
von Tempelhoff, GF1
Pollow, K1
Wang, YH1
Wu, XX1
Tan, JP1
Zhang, JP1
Kornacka, MK1
Bokiniec, R1
Schade, RR1
Van Thiel, DH1
Gavaler, JS1
Wiesner-Bornstein, R1
Niesen, M1
Grobe-Einsler, R1
Schulte-Holtey, M1
Huynh, LA1
Min, DI1
Davies, DP1
Carp, HJ1
Menashe, Y1
Frenkel, Y1
Many, A1
Nebel, L1
Toder, V1
Mashiach, S1
Framarino di Malatesta, ML1
Poli, L1
Pierucci, F1
Paolucci, A1
Pretagostini, R1
Di Nicuolo, A1
Berloco, P1
Alfani, D1
Piccioni, MG1
Veneziano, M1
Bar, J1
Fisch, B1
Wittenberg, C1
Gelerenter, I1
Boner, G1
Hod, M1
Redmond, GP1
Silveira, LH1
Hubble, CL1
Jara, LJ1
Saway, S1
Martínez-Osuna, P1
Seleznick, MJ1
Angel, J1
O'Brien, W1
Espinoza, LR1
Ville, Y1
Fernandez, H1
Edouard, D1
Frydman, R1
Houck, W1
Melnyk, C1
Gast, MJ1
Lubbe, WF1
Liggins, GC1
Branch, DW1
Scott, JR1
Kochenour, NK1
Hershgold, E1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Phase I/II, Open-Label Study to Determine Safety and Efficacy of Sotatercept (ACE-011) in Adults With Red Blood Cell Transfusion- Dependent Diamond Blackfan Anemia[NCT01464164]Phase 1/Phase 219 participants (Actual)Interventional2012-01-31Terminated (stopped due to Supporter terminated the study due to no active patients (secondary to travel restrictions due to COVID).)
Certolizumab to Prevent Pregnancy Complications in High-Risk Patients With APS or SLE - (IMPACT Study: IMProve Pregnancy in APS With Certolizumab Therapy)[NCT03152058]Phase 255 participants (Anticipated)Interventional2017-05-17Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Number of Participants With Complete Response and Partial Response

Complete response is transfusion independence with hemoglobin >9 gm/dl; partial response is transfusion dependence with hemoglobin < 9gm/dl with an increase in reticulocyte count over baseline (NCT01464164)
Timeframe: 9 months

InterventionParticipants (Count of Participants)
Sotatercept Cohort 10
Sotatercept Cohort 20
Sotatercept Cohort 30
Sotatercept With Prednisone Boost Cohort 4a0
Sotatercept Cohort 4b0
Sotatercept With Prednisone Boost Cohort 5a0
Sotatercept Cohort 5b0

Severe Adverse Events Attributable to Study Drug

Assess severity of adverse events and relationship to sotatercept according to the currently active minor version of the NCI Common Terminology for Adverse Events version 4.0 (NCT01464164)
Timeframe: 9 months

InterventionParticipants (Count of Participants)
Sotatercept Cohort 10
Sotatercept Cohort 20
Sotatercept Cohort 30
Sotatercept With Prednisone Boost Cohort 4a0
Sotatercept Cohort 4b0
Sotatercept With Prednisone Boost Cohort 5a0
Sotatercept Cohort 5b0

Reviews

5 reviews available for prednisone and Fetal Growth Restriction

ArticleYear
Antiphospholipid syndrome in obstetrics.
    Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis, 2003, Volume: 9, Issue:2

    Topics: Abortion, Habitual; Abortion, Spontaneous; Adult; Annexin A5; Antibodies, Anticardiolipin; Anticoagu

2003
[Newborn from mother with antiphospholipid syndrome].
    Polskie Archiwum Medycyny Wewnetrznej, 2006, Volume: 115, Issue:5

    Topics: Antibodies, Antiphospholipid; Antiphospholipid Syndrome; Aspirin; beta 2-Glycoprotein I; Female; Fet

2006
Outcomes of pregnancy and the management of immunosuppressive agents to minimize fetal risks in organ transplant patients.
    The Annals of pharmacotherapy, 1994, Volume: 28, Issue:12

    Topics: Azathioprine; Cyclosporine; Female; Fetal Growth Retardation; Fetus; Humans; Immunosuppressive Agent

1994
Effect of drugs on intrauterine growth.
    Clinics in perinatology, 1979, Volume: 6, Issue:1

    Topics: Abnormalities, Drug-Induced; Animals; Ethanol; Female; Fetal Growth Retardation; Fetus; Growth; Huma

1979
Lupus anticoagulant and pregnancy.
    American journal of obstetrics and gynecology, 1985, Oct-01, Volume: 153, Issue:3

    Topics: Aspirin; Autoantibodies; Blood Coagulation Factors; Female; Fetal Death; Fetal Diseases; Fetal Growt

1985

Other Studies

14 other studies available for prednisone and Fetal Growth Restriction

ArticleYear
Impact of hydroxychloroquine on preterm delivery and intrauterine growth restriction in pregnant women with systemic lupus erythematosus: a descriptive cohort study.
    Lupus, 2015, Volume: 24, Issue:13

    Topics: Adult; Antirheumatic Agents; Cohort Studies; Female; Fetal Growth Retardation; Gestational Age; Gluc

2015
Diamond-Blackfan anemia, ribosome and erythropoiesis.
    Transfusion clinique et biologique : journal de la Societe francaise de transfusion sanguine, 2010, Volume: 17, Issue:3

    Topics: Anemia; Anemia, Diamond-Blackfan; Anemia, Macrocytic; Blood Transfusion; Bone Marrow; Chromosomes, H

2010
[Takayasu's arteritis in pregnancy: report seven cases].
    Ginecologia y obstetricia de Mexico, 2011, Volume: 79, Issue:3

    Topics: Adult; Antihypertensive Agents; Cesarean Section; Female; Fetal Growth Retardation; Follow-Up Studie

2011
[Influential factors of systemic lupus erythematosus activity during pregnancy and its relationship with pregnancy outcome].
    Zhonghua fu chan ke za zhi, 2006, Volume: 41, Issue:9

    Topics: Abortion, Spontaneous; Adult; Female; Fetal Death; Fetal Growth Retardation; Gestational Age; Humans

2006
Chronic idiopathic ulcerative colitis. Pregnancy and fetal outcome.
    Digestive diseases and sciences, 1984, Volume: 29, Issue:7

    Topics: Adolescent; Adult; Apgar Score; Body Weight; Colitis, Ulcerative; Female; Fetal Growth Retardation;

1984
[Chemotherapy for Hodgkin's disease during pregnancy--a case report].
    Geburtshilfe und Frauenheilkunde, 1983, Volume: 43, Issue:6

    Topics: Adult; Doxorubicin; Female; Fetal Growth Retardation; Hodgkin Disease; Humans; Prednisone; Pregnancy

1983
Placental insufficiency and its effect on the fetus and adult disease.
    Lancet (London, England), 1993, Mar-27, Volume: 341, Issue:8848

    Topics: Female; Fetal Growth Retardation; Fetus; Humans; Infant, Newborn; Prednisone; Pregnancy

1993
Lupus anticoagulant. Significance in habitual first-trimester abortion.
    The Journal of reproductive medicine, 1993, Volume: 38, Issue:7

    Topics: Abortion, Habitual; Adult; Aspirin; Female; Fetal Death; Fetal Growth Retardation; Humans; Lupus Coa

1993
Pregnancy and kidney transplantation: clinical problems and experience.
    Transplantation proceedings, 1993, Volume: 25, Issue:3

    Topics: Abortion, Spontaneous; Azathioprine; Cesarean Section; Cyclosporine; Female; Fetal Growth Retardatio

1993
Prednisone dosage and pregnancy outcome in renal allograft recipients.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 1997, Volume: 12, Issue:4

    Topics: Abortion, Spontaneous; Adult; Cesarean Section; Female; Fetal Growth Retardation; Humans; Immunosupp

1997
Prevention of anticardiolipin antibody-related pregnancy losses with prednisone and aspirin.
    The American journal of medicine, 1992, Volume: 93, Issue:4

    Topics: Abortion, Spontaneous; Adult; Antibodies, Anticardiolipin; Antiphospholipid Syndrome; Aspirin; Enzym

1992
[Pregnancy after renal transplantation. 27 patients and review of the literature].
    Journal de gynecologie, obstetrique et biologie de la reproduction, 1992, Volume: 21, Issue:6

    Topics: Adult; Azathioprine; Birth Weight; Cesarean Section; Cyclosporine; Drug Therapy, Combination; Female

1992
Polymyositis in pregnancy. A case report and literature review.
    The Journal of reproductive medicine, 1987, Volume: 32, Issue:3

    Topics: Adult; Female; Fetal Growth Retardation; Humans; Myositis; Physical Examination; Prednisone; Pregnan

1987
Obstetric complications associated with the lupus anticoagulant.
    The New England journal of medicine, 1985, Nov-21, Volume: 313, Issue:21

    Topics: Abortion, Spontaneous; Aspirin; Blood Coagulation Factors; Blood Coagulation Tests; Female; Fetal De

1985