Page last updated: 2024-11-07

prednisone and Febrile Neutropenia

prednisone has been researched along with Febrile Neutropenia in 26 studies

Prednisone: A synthetic anti-inflammatory glucocorticoid derived from CORTISONE. It is biologically inert and converted to PREDNISOLONE in the liver.
prednisone : A synthetic glucocorticoid drug that is particularly effective as an immunosuppressant, and affects virtually all of the immune system. Prednisone is a prodrug that is converted by the liver into prednisolone (a beta-hydroxy group instead of the oxo group at position 11), which is the active drug and also a steroid.

Febrile Neutropenia: Fever accompanied by a significant reduction in the number of NEUTROPHILS.

Research Excerpts

ExcerptRelevanceReference
" S0806 was a single arm phase I/II trial of vorinostat given at 400 mg po daily on days 1-9 (subsequently amended to days 1-5 due to toxicity), combined with R-CHOP given on day 3 of a 21-day cycle for 8 cycles, with primary phase II endpoint of 2-year progression free survival (PFS)."6.87A phase I/II trial of vorinostat (SAHA) in combination with rituximab-CHOP in patients with newly diagnosed advanced stage diffuse large B-cell lymphoma (DLBCL): SWOG S0806. ( Bane, CL; Barr, PM; Fisher, RI; Friedberg, JW; LeBlanc, M; Li, H; Persky, DO; Popplewell, LL; Rimsza, LM; Smith, SM; Von Gehr, A, 2018)
"Patterns of myeloid growth factor (GF) usage and febrile neutropenia (FN) were examined in patients >60 years of age with diffuse large B-cell non-Hodgkin lymphoma (DLBCL) enrolled on CALGB 9793/ECOG-SWOG 4494, receiving initial therapy with cyclophosphamide, doxorubicin, vincristine, prednisone (CHOP) or rituximab + CHOP (R-CHOP)."5.24Patterns of growth factor usage and febrile neutropenia among older patients with diffuse large B-cell non-Hodgkin lymphoma treated with CHOP or R-CHOP: the Intergroup experience (CALGB 9793; ECOG-SWOG 4494). ( Cheson, BD; Fisher, RI; Habermann, TM; Li, S; Morrison, VA; Peterson, BA; Weller, EA, 2017)
"Febrile neutropenia (FN) can cause suboptimal treatment and treatment-related mortality (TRM) in diffuse large B-cell lymphoma (DLBCL) patients treated with rituximab, cyclophosphamide, doxorubicin, vincristine, and prednisolone (R-CHOP)."4.12Pegfilgrastim Prophylaxis Is Effective in the Prevention of Febrile Neutropenia and Reduces Mortality in Patients Aged ≥ 75 Years with Diffuse Large B-Cell Lymphoma Treated with R-CHOP: A Prospective Cohort Study. ( Choi, YS; Do, YR; Eom, HS; Hyun, SY; Jeong, SH; Jo, JC; Kang, HJ; Kim, HJ; Kim, MK; Kim, SH; Kim, SJ; Kim, WS; Koh, Y; Kwak, JY; Kwon, JH; Lee, GW; Lee, HS; Lee, WS; Oh, SY; Park, BB; Park, Y; Shin, HJ; Sohn, BS; Suh, C; Won, JH; Yang, DH; Yi, JH; Yi, SY; Yoo, KH; Yoon, DH; Yun, HJ, 2022)
", we analyzed 262 patients who had been treated with Ruximab-cyclophosphamide, doxorubicin, vincristine, and prednisone for newly diagnosed diffuse large B-cell lymphoma (DLBCL) and for whom data were available regarding pretreatment nutritional status."3.80Effect of nutritional status on survival outcome of diffuse large B-cell lymphoma patients treated with rituximab-CHOP. ( Cho, JW; Han, B; Kim, S; Kim, SJ; Kim, WS; Park, S; Woo, SY, 2014)
"An observational population-based cohort study was performed to investigate the role of comorbidity on outcome and treatment-related toxicity in patients with newly diagnosed advanced-stage diffuse large B-cell lymphoma (DLBCL) treated with R-CHOP (rituximab, cyclophosphamide, doxorubicin, vincristine, prednisone)."3.80Comorbidity is an independent prognostic factor in patients with advanced-stage diffuse large B-cell lymphoma treated with R-CHOP: a population-based cohort study. ( Beerden, T; Boslooper, K; Hoogendoorn, M; Joosten, P; Kibbelaar, RE; Kluin-Nelemans, HC; Storm, H; van Kamp, H; van Rees, B; van Roon, EN; Veeger, NJ; Veldhuis, GJ; Wieringa, A, 2014)
"Ribociclib, a CDK4/6 inhibitor, demonstrates preclinical antitumor activity in combination with taxanes."3.11A Phase Ib/II Study of the CDK4/6 Inhibitor Ribociclib in Combination with Docetaxel plus Prednisone in Metastatic Castration-Resistant Prostate Cancer. ( Aggarwal, R; Carneiro, BA; de Kouchkovsky, I; Fong, L; Friedlander, T; Lewis, C; Paris, PL; Phone, A; Rao, A; Ryan, CJ; Small, EJ; Szmulewitz, RZ; Zhang, L, 2022)
" S0806 was a single arm phase I/II trial of vorinostat given at 400 mg po daily on days 1-9 (subsequently amended to days 1-5 due to toxicity), combined with R-CHOP given on day 3 of a 21-day cycle for 8 cycles, with primary phase II endpoint of 2-year progression free survival (PFS)."2.87A phase I/II trial of vorinostat (SAHA) in combination with rituximab-CHOP in patients with newly diagnosed advanced stage diffuse large B-cell lymphoma (DLBCL): SWOG S0806. ( Bane, CL; Barr, PM; Fisher, RI; Friedberg, JW; LeBlanc, M; Li, H; Persky, DO; Popplewell, LL; Rimsza, LM; Smith, SM; Von Gehr, A, 2018)
" Efficacy assessment was based on incidence of FN and serious neutropenia (neutrophil count <500/μL), hospitalization days and chemotherapy dosage level."1.51[Comparison of Pegfilgrastim and Filgrastim for the Primary Prophylactic Effect for Preventing Febrile Neutropenia in Patients Undergoing Rituximab with Dose-adjusted EPOCH Chemotherapy]. ( Izumitani, S; Kataoka, T; Matsuo, H; Murase, T; Nishigakiuchi, R; Saeki, Y; Sakurashita, H; Taogoshi, T, 2019)

Research

Studies (26)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (3.85)29.6817
2010's16 (61.54)24.3611
2020's9 (34.62)2.80

Authors

AuthorsStudies
Matsuda, K1
Jo, T1
Shimura, A1
Honda, A1
Taoka, K1
Masamoto, Y1
Matsui, H1
Fushimi, K1
Yasunaga, H1
Kurokawa, M1
Kim, DY1
Nam, J1
Chung, JS1
Jeon, BE1
Lee, JH1
Jo, JC2
Kim, SW1
Shin, HJ3
Jeong, SH1
Kim, SJ3
Yoon, DH2
Park, Y2
Kang, HJ2
Koh, Y1
Lee, GW1
Lee, WS1
Yang, DH1
Do, YR1
Kim, MK2
Yoo, KH1
Choi, YS1
Yun, HJ1
Yi, JH1
Eom, HS2
Kwak, JY1
Park, BB1
Hyun, SY1
Yi, SY1
Kwon, JH1
Oh, SY1
Kim, HJ1
Sohn, BS1
Won, JH1
Kim, SH1
Lee, HS2
Suh, C2
Kim, WS2
de Kouchkovsky, I1
Rao, A1
Carneiro, BA1
Zhang, L1
Lewis, C1
Phone, A1
Small, EJ1
Friedlander, T1
Fong, L1
Paris, PL1
Ryan, CJ1
Szmulewitz, RZ1
Aggarwal, R1
Kim, K1
Lee, JJ1
Kim, I1
Kim, JS1
Mun, YC1
Lim, SN1
Choi, CW2
Yoon, SS1
Min, CK1
Kang, KW1
Lee, BH1
Jeon, MJ1
Yu, ES1
Kim, DS1
Lee, SR1
Sung, HJ1
Kim, BS1
de la Cruz-Benito, B1
Lázaro-Del Campo, P1
Ramírez-López, A1
de Soto-Álvarez, T1
Sánchez-Vadillo, I1
García-Pérez, E1
Dos Santos-Ortas, A1
Humala-Barbier, K1
López-de la Guía, A1
Casado-Abad, G1
Jiménez-Yuste, V1
Canales-Albendea, M1
Matsuda, S1
Suzuki, R1
Takahashi, T2
Suehiro, Y1
Tomita, N1
Izutsu, K1
Fukuhara, N1
Imaizumi, Y1
Shimada, K1
Nakazato, T2
Yoshida, I2
Miyazaki, K1
Yamaguchi, M1
Suzumiya, J1
Yokoyama, M2
Kusano, Y2
Inoue, N2
Nishimura, N2
Mishima, Y2
Nukada, T2
Hatake, K2
Terui, Y2
Arakaki, H1
Osada, Y1
Ito, C1
Aisa, Y1
Mori, T1
Takahashi, A1
Ueda, K1
Nomura, T1
Maeda, Y1
Nishimori, H1
Hiramatsu, Y1
Uno, M1
Masaki, Y1
Sunami, K1
Masunari, T1
Nawa, Y1
Yamane, H1
Gomyo, H1
Yano, T1
Matsuo, K1
Ohshima, K1
Nakamura, S1
Yoshino, T1
Tanimoto, M1
Persky, DO1
Li, H1
Rimsza, LM1
Barr, PM1
Popplewell, LL1
Bane, CL1
Von Gehr, A1
LeBlanc, M1
Fisher, RI2
Smith, SM1
Friedberg, JW1
Abdullah, AS1
Adel, AM1
Hussein, RM1
Abdullah, MA1
Yousaf, A1
Mudawi, D1
Mohamed, SF1
Nashwan, AJ1
Soliman, D1
Ibrahim, F1
Yassin, MA1
Kataoka, T1
Sakurashita, H1
Taogoshi, T1
Nishigakiuchi, R1
Murase, T1
Izumitani, S1
Saeki, Y1
Matsuo, H1
Guillet, S1
Stokkermans, J1
Vergier, B1
Doutre, MS1
Beylot-Barry, M1
Park, S1
Han, B1
Cho, JW1
Woo, SY1
Kim, S1
Wieringa, A1
Boslooper, K1
Hoogendoorn, M1
Joosten, P1
Beerden, T1
Storm, H1
Kibbelaar, RE1
Veldhuis, GJ1
van Kamp, H1
van Rees, B1
Kluin-Nelemans, HC1
Veeger, NJ1
van Roon, EN1
Odejide, OO1
Cronin, AM1
Davidoff, AJ1
LaCasce, AS1
Abel, GA1
Olszewski, AJ1
Shafqat, H1
Ali, S1
Ganti, A1
Liu, W1
Luo, S1
Sanfilippo, KM1
Roop, R1
Lynch, R1
Riedell, P1
O'Brian, K1
Colditz, GA1
Carson, KR1
Lloret-Ruiz, C1
Molés-Poveda, P1
Barrado-Solís, N1
Gimeno-Carpio, E1
Wang, XJ1
Tang, T1
Farid, M1
Quek, R1
Tao, M1
Lim, ST1
Wee, HL1
Chan, A1
Maiti, A1
Bhattacharya, S1
Abali, H1
Kiykim, AA1
Engin, H1
Güler, N1
Morrison, VA1
Weller, EA1
Habermann, TM1
Li, S1
Cheson, BD1
Peterson, BA1

Clinical Trials (3)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Phase II Study of Mogamulizumab With DA-EPOCH in Patients With Aggressive T Cell Lymphoma[NCT05996185]Phase 236 participants (Anticipated)Interventional2024-01-31Not yet recruiting
Nivolumab With Standard of Care Chemotherapy for the First Line Treatment of Peripheral T Cell Lymphoma[NCT03586999]Phase 1/Phase 218 participants (Actual)Interventional2018-11-07Active, not recruiting
Phase III Trial of CHOP Versus CHOP and Chimeric Anti-CD20 Monoclonal Antibody (IDEC-C2B8) in Older Patients With Diffuse Mixed, Diffuse Large Cell and Immunoblastic Large Cell Histology Non-Hodgkin's Lymphoma[NCT00003150]Phase 3630 participants (Anticipated)Interventional1997-12-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

5 trials available for prednisone and Febrile Neutropenia

ArticleYear
A Phase Ib/II Study of the CDK4/6 Inhibitor Ribociclib in Combination with Docetaxel plus Prednisone in Metastatic Castration-Resistant Prostate Cancer.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2022, 04-14, Volume: 28, Issue:8

    Topics: Aminopyridines; Antineoplastic Combined Chemotherapy Protocols; Cyclin-Dependent Kinase 4; Docetaxel

2022
Pomalidomide, cyclophosphamide, and dexamethasone for elderly patients with relapsed and refractory multiple myeloma: A study of the Korean Multiple Myeloma Working Party (KMMWP-164 study).
    American journal of hematology, 2020, Volume: 95, Issue:4

    Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Bortezomib; Cyclophosphamid

2020
Dose-adjusted EPOCH chemotherapy for untreated peripheral T-cell lymphomas: a multicenter phase II trial of West-JHOG PTCL0707.
    Haematologica, 2017, Volume: 102, Issue:12

    Topics: Adult; Age Factors; Aged; Anemia; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide;

2017
Dose-adjusted EPOCH chemotherapy for untreated peripheral T-cell lymphomas: a multicenter phase II trial of West-JHOG PTCL0707.
    Haematologica, 2017, Volume: 102, Issue:12

    Topics: Adult; Age Factors; Aged; Anemia; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide;

2017
Dose-adjusted EPOCH chemotherapy for untreated peripheral T-cell lymphomas: a multicenter phase II trial of West-JHOG PTCL0707.
    Haematologica, 2017, Volume: 102, Issue:12

    Topics: Adult; Age Factors; Aged; Anemia; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide;

2017
Dose-adjusted EPOCH chemotherapy for untreated peripheral T-cell lymphomas: a multicenter phase II trial of West-JHOG PTCL0707.
    Haematologica, 2017, Volume: 102, Issue:12

    Topics: Adult; Age Factors; Aged; Anemia; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide;

2017
A phase I/II trial of vorinostat (SAHA) in combination with rituximab-CHOP in patients with newly diagnosed advanced stage diffuse large B-cell lymphoma (DLBCL): SWOG S0806.
    American journal of hematology, 2018, Volume: 93, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Cy

2018
Patterns of growth factor usage and febrile neutropenia among older patients with diffuse large B-cell non-Hodgkin lymphoma treated with CHOP or R-CHOP: the Intergroup experience (CALGB 9793; ECOG-SWOG 4494).
    Leukemia & lymphoma, 2017, Volume: 58, Issue:8

    Topics: Age Factors; Aged; Aged, 80 and over; Antibodies, Monoclonal, Murine-Derived; Antineoplastic Combine

2017

Other Studies

21 other studies available for prednisone and Febrile Neutropenia

ArticleYear
Risk of febrile neutropenia in very elderly patients aged ≥80 years receiving their first cycle of R-CHOP regimen: a nationwide real-world study in Japan.
    British journal of haematology, 2022, Volume: 197, Issue:3

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Doxorubicin; Febrile Neutrop

2022
Predictive Parameters of Febrile Neutropenia and Clinical Significance of G-CSF Receptor Signaling Pathway in the Development of Neutropenia during R-CHOP Chemotherapy with Prophylactic Pegfilgrastim in Patients with Diffuse Large B-Cell Lymphoma.
    Cancer research and treatment, 2022, Volume: 54, Issue:4

    Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Doxorubicin

2022
Pegfilgrastim Prophylaxis Is Effective in the Prevention of Febrile Neutropenia and Reduces Mortality in Patients Aged ≥ 75 Years with Diffuse Large B-Cell Lymphoma Treated with R-CHOP: A Prospective Cohort Study.
    Cancer research and treatment, 2022, Volume: 54, Issue:4

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Doxorubicin; Febrile Neutrop

2022
Efficacy and safety of two pegfilgrastim biosimilars: Tripegfilgrastim and pegteograstim.
    Cancer medicine, 2020, Volume: 9, Issue:17

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Bacterial Infections

2020
Managing the front-line treatment for diffuse large B cell lymphoma and high-grade B cell lymphoma during the COVID-19 outbreak.
    British journal of haematology, 2020, Volume: 191, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Antineoplastic Combined Chemotherapy Protocol

2020
Dose-adjusted EPOCH with or without rituximab for aggressive lymphoma patients: real world data.
    International journal of hematology, 2020, Volume: 112, Issue:6

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Communic

2020
Factors for the optimal selection of granulocyte colony-stimulating factor preparations and predictors for R-CHOP dose reductions/delays among patients with non-Hodgkin B-cell lymphoma (STOP FN in NHL 2 subanalysis).
    BMC cancer, 2021, Apr-06, Volume: 21, Issue:1

    Topics: Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Doxorubicin; Febrile Neutropenia;

2021
Comparison of R-CVP with R-CHOP for very elderly patients aged 80 or over with diffuse large B cell lymphoma.
    Annals of hematology, 2017, Volume: 96, Issue:7

    Topics: Aged, 80 and over; Aging; Antibodies, Monoclonal, Murine-Derived; Antineoplastic Combined Chemothera

2017
Incidence and risk factors of febrile neutropenia in patients with non-Hodgkin B-cell lymphoma receiving R-CHOP in a single center in Japan.
    Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2017, Volume: 25, Issue:11

    Topics: Antibodies, Monoclonal, Murine-Derived; Antineoplastic Combined Chemotherapy Protocols; Cyclophospha

2017
Hypercalcemia and acute pancreatitis in a male patient with acute promyelocytic leukemia and pulmonary tuberculosis.
    Acta bio-medica : Atenei Parmensis, 2018, 04-03, Volume: 89, Issue:3-S

    Topics: Acute Disease; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Causality; Febrile Neut

2018
[Comparison of Pegfilgrastim and Filgrastim for the Primary Prophylactic Effect for Preventing Febrile Neutropenia in Patients Undergoing Rituximab with Dose-adjusted EPOCH Chemotherapy].
    Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 2019, Volume: 139, Issue:4

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Doxorubicin; Etoposid

2019
[Acute neutrophilic dermatosis (pustular dermatitis) associated with aggressive transformed mycosis fungoides].
    Annales de dermatologie et de venereologie, 2013, Volume: 140, Issue:10

    Topics: Adrenal Cortex Hormones; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Depsipept

2013
Effect of nutritional status on survival outcome of diffuse large B-cell lymphoma patients treated with rituximab-CHOP.
    Nutrition and cancer, 2014, Volume: 66, Issue:2

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anthropometry; Antibodies, Monoclonal, Murine-Derived; A

2014
Comorbidity is an independent prognostic factor in patients with advanced-stage diffuse large B-cell lymphoma treated with R-CHOP: a population-based cohort study.
    British journal of haematology, 2014, Volume: 165, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Antibodies, Monoclonal, Murine-Derived; Antineoplastic Combined Chem

2014
Limited stage diffuse large B-cell lymphoma: comparative effectiveness of treatment strategies in a large cohort of elderly patients.
    Leukemia & lymphoma, 2015, Volume: 56, Issue:3

    Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Chemoradiotherapy; Cohort S

2015
Disparate survival outcomes after front-line chemoimmunotherapy in older patients with follicular, nodal marginal zone and small lymphocytic lymphoma.
    Leukemia & lymphoma, 2015, Volume: 56, Issue:4

    Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Doxorubic

2015
Impact of body mass index on incidence of febrile neutropenia and treatment-related mortality in United States veterans with diffuse large B-cell lymphoma receiving rituximab, cyclophosphamide, doxorubicin, vincristine, prednisone.
    British journal of haematology, 2014, Volume: 167, Issue:5

    Topics: Aged; Antibodies, Monoclonal, Murine-Derived; Antineoplastic Combined Chemotherapy Protocols; Body M

2014
Diffuse systemic large B-cell lymphoma with secondary skin involvement.
    Actas dermo-sifiliograficas, 2015, Volume: 106, Issue:8

    Topics: Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; B-Lymphocytes; Biomarkers, Tumor;

2015
Routine Primary Prophylaxis for Febrile Neutropenia with Biosimilar Granulocyte Colony-Stimulating Factor (Nivestim) or Pegfilgrastim Is Cost Effective in Non-Hodgkin Lymphoma Patients undergoing Curative-Intent R-CHOP Chemotherapy.
    PloS one, 2016, Volume: 11, Issue:2

    Topics: Antibodies, Monoclonal, Murine-Derived; Antineoplastic Combined Chemotherapy Protocols; Biosimilar P

2016
A patient with cancer and nail pigmentation.
    BMJ (Clinical research ed.), 2016, 05-03, Volume: 353

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Black or African American; Cyclophosphamide;

2016
Is Granulocyte Colony-stimulating Factor Safe in the Treatment of Febrile Neutropenia in Lymphoma Patients with Renal Transplantation?
    Hematology (Amsterdam, Netherlands), 2001, Volume: 6, Issue:6

    Topics: Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Doxorubicin; Febrile Neutropenia;

2001