prednisone has been researched along with Exanthema in 89 studies
Prednisone: A synthetic anti-inflammatory glucocorticoid derived from CORTISONE. It is biologically inert and converted to PREDNISOLONE in the liver.
prednisone : A synthetic glucocorticoid drug that is particularly effective as an immunosuppressant, and affects virtually all of the immune system. Prednisone is a prodrug that is converted by the liver into prednisolone (a beta-hydroxy group instead of the oxo group at position 11), which is the active drug and also a steroid.
Exanthema: Diseases in which skin eruptions or rashes are a prominent manifestation. Classically, six such diseases were described with similar rashes; they were numbered in the order in which they were reported. Only the fourth (Duke's disease), fifth (ERYTHEMA INFECTIOSUM), and sixth (EXANTHEMA SUBITUM) numeric designations survive as occasional synonyms in current terminology.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We conducted a phase III study to test the hypothesis that initial therapy with "lower dose" prednisone is effective and safe for patients with newly diagnosed acute graft-versus-host disease." | 9.20 | Effectiveness and safety of lower dose prednisone for initial treatment of acute graft-versus-host disease: a randomized controlled trial. ( Boeckh, M; Carpenter, PA; Flowers, ME; Furlong, T; Green, ML; Martin, PJ; McDonald, GB; Mielcarek, M; Storb, R; Storer, BE, 2015) |
| "To examine the effect of 2 weeks of treatment with prednisone on the incidence of nevirapine-associated rash in HIV-1-infected patients receiving combination antiretroviral therapy." | 9.10 | Randomized, controlled study of the effects of a short course of prednisone on the incidence of rash associated with nevirapine in patients infected with HIV-1. ( Cahn, P; Casssetti, LI; Gigliotti, M; Hall, DB; Losso, M; McDonough, M; Montaner, JS; Robinson, PA; Wruck, J; Zala, C, 2003) |
| "► Prednisone therapy to treat nephrotic syndrome ► Diffuse maculopapular rash ► Pruritis." | 7.96 | 24-year-old man • prednisone therapy for nephrotic syndrome • diffuse maculopapular rash • pruritis • Dx? ( Hepner, MJ; Soifer, NE, 2020) |
| "A retrospective analysis comparing the first-time use of levamisole (L) or cyclophosphamide (C) as second-line therapy for children with frequently relapsing, steroid-dependent (FR/SD) nephrotic syndrome, was conducted at our center." | 7.71 | Levamisole vs. cyclophosphamide for frequently-relapsing steroid-dependent nephrotic syndrome. ( Alsaran, K; Arbus, G; Grisaru, S; Stephens, D, 2001) |
| "The appearance of rash is one of the most frequent and limiting side-effects during the first 4 weeks of treatment with nevirapine (NVP)." | 6.69 | Prevention of nevirapine-associated exanthema using slow dose escalation and/or corticosteroids. ( Barreiro, P; Casas, E; de Requena, DG; Estrada, V; González-Lahoz, J; Hoetelmans, R; Jimenéz-Nácher, I; Soriano, V; Téllez, MJ, 2000) |
| "We conducted a phase III study to test the hypothesis that initial therapy with "lower dose" prednisone is effective and safe for patients with newly diagnosed acute graft-versus-host disease." | 5.20 | Effectiveness and safety of lower dose prednisone for initial treatment of acute graft-versus-host disease: a randomized controlled trial. ( Boeckh, M; Carpenter, PA; Flowers, ME; Furlong, T; Green, ML; Martin, PJ; McDonald, GB; Mielcarek, M; Storb, R; Storer, BE, 2015) |
| "To examine the effect of 2 weeks of treatment with prednisone on the incidence of nevirapine-associated rash in HIV-1-infected patients receiving combination antiretroviral therapy." | 5.10 | Randomized, controlled study of the effects of a short course of prednisone on the incidence of rash associated with nevirapine in patients infected with HIV-1. ( Cahn, P; Casssetti, LI; Gigliotti, M; Hall, DB; Losso, M; McDonough, M; Montaner, JS; Robinson, PA; Wruck, J; Zala, C, 2003) |
| "► Prednisone therapy to treat nephrotic syndrome ► Diffuse maculopapular rash ► Pruritis." | 3.96 | 24-year-old man • prednisone therapy for nephrotic syndrome • diffuse maculopapular rash • pruritis • Dx? ( Hepner, MJ; Soifer, NE, 2020) |
| " Azathioprine has a significant early adverse reaction (EAR) profile, which includes an acute syndrome of constitutional symptoms, fever, rash, and acute pancreatitis and often requires discontinuation of drug." | 3.73 | Increased rates of early adverse reaction to azathioprine in patients with Crohn's disease compared to autoimmune hepatitis: a tertiary referral center experience. ( Bajaj, JS; Binion, DG; Emmons, J; Franco, J; Knox, JF; Levy, M; Podoll, J; Saeian, K; Varma, RR, 2005) |
| "We report on six cases of skin lesions induced by bortezomib in patients treated for relapsed multiple myeloma." | 3.73 | Skin lesions induced by bortezomib. ( Hajek, R; Krejci, M; Krivanova, A; Pour, L; Vorlicek, J; Zdenek, A, 2005) |
| "A 27-year-old man with Crohn disease developed a rash while taking mesalamine (Pentasa and Asacol)." | 3.73 | Lack of cross-reactivity between 5-aminosalicylic acid-based drugs: a case report and review of the literature. ( Choudhary, C; Cohn, JR; Kung, SJ; McGeady, SJ, 2006) |
| "A retrospective analysis comparing the first-time use of levamisole (L) or cyclophosphamide (C) as second-line therapy for children with frequently relapsing, steroid-dependent (FR/SD) nephrotic syndrome, was conducted at our center." | 3.71 | Levamisole vs. cyclophosphamide for frequently-relapsing steroid-dependent nephrotic syndrome. ( Alsaran, K; Arbus, G; Grisaru, S; Stephens, D, 2001) |
| " Here we characterise the safety of these agents in subpopulations and assess manageability of key adverse events (AEs)." | 3.30 | Safety Profile of Ipatasertib Plus Abiraterone vs Placebo Plus Abiraterone in Metastatic Castration-resistant Prostate Cancer. ( Bracarda, S; Chen, G; Chi, KN; de Bono, J; Garcia, J; Harris, A; Hinton, H; Massard, C; Matsubara, N; Olmos, D; Sandhu, S; Sane, R; Schenkel, F; Sternberg, CN; Sweeney, C, 2023) |
| "Panniculitis is a disease characterized by inflammation of subcutaneous adipose tissue." | 2.82 | [Ruxolitinib as an effective treatment for panniculitis associated hemophagocytic syndrome: A report of 2 cases and literature review]. ( Chen, C; Gan, YZ; Jia, Y; Jin, YB; Li, C; Li, GM, 2022) |
| "Rash is the most frequent adverse event associated with nevirapine." | 2.70 | Failure of a short-term prednisone regimen to prevent nevirapine-associated rash: a double-blind placebo-controlled trial: the GESIDA 09/99 study. ( Blanco, JL; Boix, V; De Miguel, V; Domingo, P; Force, L; González, A; Knobel, H; Locutura, J; Márquez, M; Miró, JM; Rivero, A; Sanz, J, 2001) |
| "The appearance of rash is one of the most frequent and limiting side-effects during the first 4 weeks of treatment with nevirapine (NVP)." | 2.69 | Prevention of nevirapine-associated exanthema using slow dose escalation and/or corticosteroids. ( Barreiro, P; Casas, E; de Requena, DG; Estrada, V; González-Lahoz, J; Hoetelmans, R; Jimenéz-Nácher, I; Soriano, V; Téllez, MJ, 2000) |
| "While skin rashes are a common presentation of neonatal LCH, other systems or organs may also be involved." | 2.55 | Delayed Treatment Response in a Neonate with Multisystem Langerhans Cell Histiocytosis Case report and review of literature. ( Mandal, A; Mishra, S; Patel, A; Singh, A; Singh, L, 2017) |
| "Fever, arthritis and skin rash was constant." | 2.41 | [Adult Still's disease: study of a series of 11 cases]. ( Ben Maïz, H; Ben Taarit, C; Turki, S, 2002) |
| "Leprosy is rare within non-endemic countries such as Canada, where cases are almost exclusively imported from endemic regions, often presenting after an incubation period of as many as 20 years." | 1.91 | Leprosy with type 1 reaction in a patient from Ontario, Canada without recent travel misdiagnosed as vasculitic neuropathy: a case report. ( Driedger, M; Roth, V; Teo, I, 2023) |
| "Treatment with colchicine and prednisone resulted in rapid improvement of his symptoms." | 1.43 | Oral ulcerations after placement of orthodontic braces and skin pustules after laser hair removal: novel inducers of pathergy reactions in new-onset Behçet's disease. ( Kiewiet-Kemper, RM; Tchetverikov, I; van de Ree-Pellikaan, C; Westerweel, PE, 2016) |
| "After being treated for venous insufficiency and malleolus ulceration, this patient woke up covered in itchy, painful plaques." | 1.43 | Generalized rash follows ankle ulceration. ( Bucher, J; Osswald, S; Rahnama-Moghadam, S, 2016) |
| "DRESS Syndrome (Drug Reaction with Eosinophilia and Systemic Symptoms) is an uncommon disease caused by drugs." | 1.42 | [DRESS syndrome: Report of nine cases]. ( Barbosa-Moreno, LE; Guerrero-González, GA; Martínez-Villarreal, JD; Ocampo-Candiani, J; Ocampo-Garza, J; Ocampo-Garza, SS, 2015) |
| "Oral prednisone was prescribed at 2 mg/kg/day for 2 months until when subcutaneous nodules and joint swellings almost disappeared, and then slowly tapered over a period of 5 months." | 1.38 | Early-onset childhood sarcoidosis with incidental multiple enchondromatosis. ( Choi, YY; Joo, KB; Lee, JH; Lee, S; Lee, YH; Lim, YJ; Park, CK, 2012) |
| "We report on a patient with Pneumocystis jirovecii pneumonia who developed fever, rash, eosinophilia and hepatitis 10 days after initiation of a therapy with sulfamethoxazole and trimethoprim." | 1.36 | [Rash, fever, eosinophilia and elevated liver enzymes. DRESS syndrome (drug reaction or rash with eosinophilia and systemic symptoms)]. ( Derungs, A; Kummer, O; Rätz Bravo, AE, 2010) |
| "Prednisone is commonly used to treat rash, a potentially harmful side effect of nevirapine." | 1.31 | Nevirapine, prednisone and rash. ( , 2000) |
| " This new product has been well received due to convenient dosing and relatively few side effects." | 1.30 | Churg-Strauss syndrome associated with zafirlukast. ( Allen, JN; Knoell, DL; Lucas, J, 1998) |
| "HIDS and CINCA syndrome are not known to be modified by any effective therapeutic agent." | 1.30 | [Pseudo-periodic disease with hyperimmunoglobulinemia D: a never-ending story with probable prenatal onset]. ( Breton, A; Carrière, JP; Chaix, Y; Claeyssens, S; Graber, D; Grouteau, E; Kuhlein, E, 1998) |
| "A case of acute generalized exanthematous pustulosis (AGEP) is described." | 1.29 | Acute generalized exanthematous pustulosis. ( Artemi, P; Holt, D; Lee, S, 1995) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 14 (15.73) | 18.7374 |
| 1990's | 6 (6.74) | 18.2507 |
| 2000's | 25 (28.09) | 29.6817 |
| 2010's | 35 (39.33) | 24.3611 |
| 2020's | 9 (10.11) | 2.80 |
| Authors | Studies |
|---|---|
| Kam, S | 1 |
| Ishii, L | 1 |
| Zwerner, JP | 2 |
| Dewan, AK | 1 |
| Huynh, LM | 1 |
| Bonebrake, BT | 1 |
| DiMaio, DJ | 1 |
| Baine, MJ | 1 |
| Teply, BA | 1 |
| Weisnicht, AM | 1 |
| Byrne, R | 1 |
| Henkel, EB | 1 |
| Harding, SA | 1 |
| Kostelyna, SP | 1 |
| Schady, D | 1 |
| Lai, J | 1 |
| Stubbs, LA | 1 |
| Li, GM | 1 |
| Jin, YB | 1 |
| Gan, YZ | 1 |
| Chen, C | 1 |
| Jia, Y | 1 |
| Li, C | 1 |
| Matsubara, N | 1 |
| de Bono, J | 1 |
| Sweeney, C | 1 |
| Chi, KN | 1 |
| Olmos, D | 1 |
| Sandhu, S | 1 |
| Massard, C | 1 |
| Garcia, J | 1 |
| Chen, G | 1 |
| Harris, A | 1 |
| Schenkel, F | 1 |
| Sane, R | 1 |
| Hinton, H | 1 |
| Bracarda, S | 1 |
| Sternberg, CN | 1 |
| Driedger, M | 1 |
| Teo, I | 1 |
| Roth, V | 1 |
| Jithpratuck, W | 1 |
| Kays, D | 1 |
| Sriaroon, P | 1 |
| Soifer, NE | 1 |
| Hepner, MJ | 1 |
| Treichel, AM | 1 |
| Teske, N | 1 |
| Vandergriff, T | 1 |
| Dominguez, A | 1 |
| Mauskar, MM | 1 |
| Nguyen, KD | 1 |
| Singh, A | 1 |
| Mandal, A | 1 |
| Singh, L | 1 |
| Mishra, S | 1 |
| Patel, A | 1 |
| Ergen, EN | 1 |
| Garje, R | 1 |
| Chau, JJ | 1 |
| Chung, J | 1 |
| Wanat, K | 1 |
| Zakharia, Y | 1 |
| Vinnakota, S | 1 |
| Salonen, BR | 1 |
| Deng, W | 1 |
| Miao, C | 1 |
| Zhang, X | 1 |
| Tidwell, WJ | 1 |
| Callen, JP | 1 |
| Iriki, H | 1 |
| Ouchi, T | 1 |
| Ito, H | 1 |
| Sawada, M | 1 |
| Mukai, M | 1 |
| Nomura, H | 1 |
| Baba, Y | 1 |
| Adachi, T | 1 |
| Funakoshi, T | 1 |
| Amagai, M | 1 |
| Takahashi, H | 1 |
| Maxfield, L | 1 |
| Peck, A | 1 |
| Youngblood, LB | 1 |
| Nambiar, PH | 1 |
| Katikaneni, M | 1 |
| Al Nahlawi, B | 1 |
| Hayat, SQ | 1 |
| Mameli, C | 1 |
| Tadini, G | 1 |
| Cattaneo, D | 1 |
| Cerini, C | 1 |
| Zuccotti, GV | 1 |
| Huston, B | 1 |
| Froloff, V | 1 |
| Mills, K | 1 |
| McGee, M | 1 |
| Levin, C | 1 |
| Rozemman, D | 1 |
| Sakran, W | 1 |
| Halevy, R | 1 |
| Peleg, S | 1 |
| Koren, A | 1 |
| Lau, EG | 1 |
| Stepenaskie, S | 1 |
| Moran, R | 1 |
| Quinn, R | 1 |
| Matthew, P | 1 |
| Smidt, AC | 1 |
| Pukkila-Worley, R | 1 |
| Nardi, V | 1 |
| Branda, JA | 1 |
| Parlow, B | 1 |
| Mohiuddin, A | 1 |
| Chou, T | 1 |
| Cato-Varlack, J | 1 |
| Boneparth, A | 1 |
| Moorthy, LN | 1 |
| Escudero-Vilaplana, V | 1 |
| Osorio Prendes, S | 1 |
| Sanjurjo Sáez, M | 1 |
| Mielcarek, M | 1 |
| Furlong, T | 2 |
| Storer, BE | 1 |
| Green, ML | 1 |
| McDonald, GB | 1 |
| Carpenter, PA | 2 |
| Flowers, ME | 1 |
| Storb, R | 2 |
| Boeckh, M | 1 |
| Martin, PJ | 2 |
| Munzer, TG | 1 |
| Shah, MD | 1 |
| Stojan, JN | 1 |
| Ocampo-Garza, J | 1 |
| Ocampo-Garza, SS | 1 |
| Martínez-Villarreal, JD | 1 |
| Barbosa-Moreno, LE | 1 |
| Guerrero-González, GA | 1 |
| Ocampo-Candiani, J | 1 |
| van de Ree-Pellikaan, C | 1 |
| Kiewiet-Kemper, RM | 1 |
| Tchetverikov, I | 1 |
| Westerweel, PE | 1 |
| Jumean, K | 1 |
| Shaaban, H | 1 |
| Bucher, J | 1 |
| Rahnama-Moghadam, S | 1 |
| Osswald, S | 1 |
| Gawin, A | 1 |
| Lyon, C | 1 |
| Khodaee, M | 1 |
| Agha-Abbaslou, M | 1 |
| Bensaci, AM | 1 |
| Dike, O | 1 |
| Poznansky, MC | 1 |
| Hyat, A | 1 |
| Brown, ML | 1 |
| Chesney, PJ | 1 |
| Ault, BH | 1 |
| Delos Santos, NM | 1 |
| Truong, LD | 1 |
| Lohr, KM | 1 |
| Myers, LK | 1 |
| Zeng, T | 1 |
| Zou, YQ | 1 |
| Wu, MF | 1 |
| Yang, CD | 1 |
| Marneros, AG | 1 |
| Grossman, ME | 1 |
| Silvers, DN | 1 |
| Husain, S | 1 |
| Nuovo, GJ | 1 |
| MacGregor-Cortelli, B | 1 |
| Neylon, E | 1 |
| Patterson, M | 1 |
| O'Connor, OA | 1 |
| Zain, JM | 1 |
| Lieberman, SM | 1 |
| Sherry, DD | 1 |
| Bowman, ME | 1 |
| Robinson, JL | 1 |
| Ross, JJ | 1 |
| Saavedra, A | 1 |
| Vleugels, RA | 1 |
| Liu, A | 1 |
| Castells, MC | 1 |
| Derungs, A | 1 |
| Rätz Bravo, AE | 1 |
| Kummer, O | 1 |
| Liu, AY | 1 |
| Lowe, RC | 1 |
| Levy, BD | 1 |
| Katz, JT | 1 |
| Loscalzo, J | 1 |
| Rajabally, MN | 1 |
| Watermeyer, GA | 1 |
| Levin, DA | 1 |
| Richmond, BW | 1 |
| Cole, MB | 1 |
| Dash, A | 1 |
| Eyler, A | 1 |
| Boomershine, CS | 1 |
| Lee, JH | 1 |
| Lim, YJ | 1 |
| Lee, S | 2 |
| Joo, KB | 1 |
| Choi, YY | 1 |
| Park, CK | 1 |
| Lee, YH | 1 |
| Fleming, MT | 1 |
| Sonpavde, G | 1 |
| Kolodziej, M | 1 |
| Awasthi, S | 1 |
| Hutson, TE | 1 |
| Martincic, D | 1 |
| Rastogi, A | 1 |
| Rousey, SR | 1 |
| Weinstein, RE | 1 |
| Galsky, MD | 1 |
| Berry, WR | 1 |
| Wang, Y | 1 |
| Boehm, KA | 1 |
| Asmar, L | 1 |
| Rauch, MA | 1 |
| Beer, TM | 1 |
| Peterson, GB | 1 |
| Criscione-Schreiber, LG | 1 |
| Barker, S | 1 |
| Scott, M | 1 |
| Chan, GT | 1 |
| Sin, C | 1 |
| Mahé, E | 1 |
| Sigal, ML | 1 |
| Montaner, JS | 1 |
| Cahn, P | 1 |
| Zala, C | 1 |
| Casssetti, LI | 1 |
| Losso, M | 1 |
| Hall, DB | 1 |
| Wruck, J | 1 |
| McDonough, M | 1 |
| Gigliotti, M | 1 |
| Robinson, PA | 1 |
| WENGER, R | 1 |
| KRIEHUBER, E | 1 |
| OBIDITSCH-MAYER, I | 1 |
| WALLACE, HJ | 1 |
| Bajaj, JS | 1 |
| Saeian, K | 1 |
| Varma, RR | 1 |
| Franco, J | 1 |
| Knox, JF | 1 |
| Podoll, J | 1 |
| Emmons, J | 1 |
| Levy, M | 1 |
| Binion, DG | 1 |
| Haque, FN | 1 |
| Kaplan, J | 1 |
| Frieri, M | 1 |
| Goodall, J | 1 |
| Usatine, RP | 1 |
| Kay, J | 1 |
| McCluskey, RT | 1 |
| Lau, KK | 1 |
| Wyatt, RJ | 1 |
| Gaber, LW | 1 |
| Pour, L | 1 |
| Hajek, R | 1 |
| Zdenek, A | 1 |
| Krejci, M | 1 |
| Krivanova, A | 1 |
| Vorlicek, J | 1 |
| Xia, ZJ | 1 |
| Wang, FH | 1 |
| Huang, HQ | 1 |
| Luo, HY | 1 |
| Li, YH | 1 |
| Lin, TY | 1 |
| Jiang, WQ | 1 |
| Guan, ZZ | 1 |
| McCann, DJ | 1 |
| Nadel, ES | 1 |
| Brown, DF | 1 |
| Kung, SJ | 1 |
| Choudhary, C | 1 |
| McGeady, SJ | 1 |
| Cohn, JR | 1 |
| Ambrocio, DU | 1 |
| John, D | 1 |
| Burco, K | 1 |
| Zenel, JA | 1 |
| Arnson, Y | 1 |
| Dovrish, Z | 1 |
| Hadari, R | 1 |
| Amital, H | 1 |
| Fernández Fernández, FJ | 1 |
| Puerta Louro, R | 1 |
| González Vázquez, L | 1 |
| Soto Ríos, C | 1 |
| de la Fuente Aguado, J | 1 |
| Weisdorf, D | 1 |
| Rudkowski, Z | 1 |
| Wasik, F | 1 |
| Chabudzinska, S | 1 |
| Saraczynska, E | 1 |
| Artemi, P | 1 |
| Holt, D | 1 |
| Achermann, E | 1 |
| Bingisser, R | 1 |
| Krause, M | 1 |
| Knoell, DL | 1 |
| Lucas, J | 1 |
| Allen, JN | 1 |
| Grouteau, E | 1 |
| Chaix, Y | 1 |
| Graber, D | 1 |
| Breton, A | 1 |
| Claeyssens, S | 1 |
| Kuhlein, E | 1 |
| Carrière, JP | 1 |
| Carneiro, JR | 1 |
| Sato, EI | 1 |
| Shekarappa, RJ | 1 |
| Nikolinakos, P | 1 |
| Bansidhar, T | 1 |
| Sistoza, E | 1 |
| Smith, J | 1 |
| Barreiro, P | 1 |
| Soriano, V | 1 |
| Casas, E | 1 |
| Estrada, V | 1 |
| Téllez, MJ | 1 |
| Hoetelmans, R | 1 |
| de Requena, DG | 1 |
| Jimenéz-Nácher, I | 1 |
| González-Lahoz, J | 1 |
| Knobel, H | 1 |
| Miró, JM | 1 |
| Domingo, P | 1 |
| Rivero, A | 1 |
| Márquez, M | 1 |
| Force, L | 1 |
| González, A | 1 |
| De Miguel, V | 1 |
| Sanz, J | 1 |
| Boix, V | 1 |
| Blanco, JL | 1 |
| Locutura, J | 1 |
| Alsaran, K | 1 |
| Grisaru, S | 1 |
| Stephens, D | 1 |
| Arbus, G | 1 |
| Leisenring, W | 1 |
| Anasetti, C | 1 |
| Appelbaum, FR | 1 |
| Deeg, HJ | 1 |
| Doney, K | 1 |
| Kiem, HP | 1 |
| Nash, RA | 1 |
| Sanders, JE | 1 |
| Witherspoon, R | 1 |
| Thompson, D | 1 |
| Ben Taarit, C | 1 |
| Turki, S | 1 |
| Ben Maïz, H | 1 |
| Pedersen, FK | 1 |
| Petersen, EA | 1 |
| Woldoff, HS | 1 |
| Waldmann, EB | 1 |
| Rothfield, NF | 1 |
| Just, L | 1 |
| Schieche, M | 1 |
| Woit, I | 1 |
| Zanoni, G | 1 |
| Scholer, H | 1 |
| Krebs, A | 1 |
| Stoll, E | 1 |
| Williner, B | 1 |
| Rubinstein, A | 1 |
| Zala, L | 1 |
| Henningsen, B | 1 |
| Maintz, J | 1 |
| Basedow, M | 1 |
| Harders, H | 1 |
| Lalla, M | 1 |
| Virolainen, M | 1 |
| Standau, H | 1 |
| Schmidt, U | 1 |
| Kunad, T | 1 |
| Michel, H | 1 |
| Bártová, J | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Randomized Phase II Study of Mitoxantrone vs. Mitoxantrone With Cetuximab in Metastatic Androgen Independent Prostate Cancer (AIPC) Previously Treated With Docetaxel-based Chemotherapy[NCT00661492] | Phase 2 | 115 participants (Actual) | Interventional | 2008-05-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
"Radiographic progression:~1) For bone scan, 2 unequivocal new lesions confirmed by a subsequent bone scan with at least 1 more new lesion; 2) Skeletal related event (eg, fracture, need for radiation to bone for pain, spinal cord compression, need for surgery to bone to prevent or treat a pathologic fracture)." (NCT00661492)
Timeframe: 24 months.
| Intervention | Probability of REPFS at 2-year (Number) |
|---|---|
| Arm 1 | 0.73 |
| Arm 2 | 0.80 |
OS is measured from the date of randomization to the date of death for a dead patient. If a patient is still alive or is lost to follow up, the patient will be censored at the last contact date. (NCT00661492)
Timeframe: 30 months
| Intervention | months (Median) |
|---|---|
| Arm 1 | 11.9 |
| Arm 2 | 15.7 |
PFS is measured from the date of randomization to the date of first documented disease progression or date of death, whichever comes first. If a patient neither progresses nor dies, this patient will be censored at last contact date. (NCT00661492)
Timeframe: 24 months
| Intervention | months (Median) |
|---|---|
| Arm 1 | 4.2 |
| Arm 2 | 5.5 |
TTP will be measured from the start of treatment date to the date the patient is first recorded as having disease progression (even in patients who discontinue study treatment early due to toxicity or death due to disease progression. (NCT00661492)
Timeframe: 24 months
| Intervention | Months (Median) |
|---|---|
| Arm 1 | 4.9 |
| Arm 2 | 6.6 |
Defined as the time from initiation of therapy until the first 25% increase from baseline in non-responders or 50% increase from nadir in responders as defined above. A minimum increase in the PSA of 5 ng/mL will be required for progression. (NCT00661492)
Timeframe: 24 months
| Intervention | Months (Median) |
|---|---|
| Arm 1 | 2.7 |
| Arm 2 | 2.7 |
ORR = CR + PR Complete Response (CR): Disappearance of all target lesions. Partial Response (PR): At least a 30% decrease in the sum of the LD of target lesions taking as reference the baseline sum LD. (NCT00661492)
Timeframe: 24 months
| Intervention | percentage of participants (Number) |
|---|---|
| Arm 1 | 2.2 |
| Arm 2 | 3.8 |
PSA doubling time = [log (2)× t] ÷ [log (final PSA) - log (initial PSA)] (NCT00661492)
Timeframe: 24 months
| Intervention | months (Median) |
|---|---|
| Arm 1 | 2.3 |
| Arm 2 | 1.5 |
Defined as the fraction of patients with a ≥50% reduction in serum PSA confirmed by a second serum PSA at least 3 weeks later (NCT00661492)
Timeframe: 24 months
| Intervention | percentage of participants (Number) |
|---|---|
| Arm 1 | 7.7 |
| Arm 2 | 17.6 |
4 reviews available for prednisone and Exanthema
| Article | Year |
|---|---|
[Ruxolitinib as an effective treatment for panniculitis associated hemophagocytic syndrome: A report of 2 cases and literature review].
Topics: Aged; Anti-Bacterial Agents; Dexamethasone; Epstein-Barr Virus Infections; Etoposide; Exanthema; Fem | 2022 |
Delayed Treatment Response in a Neonate with Multisystem Langerhans Cell Histiocytosis Case report and review of literature.
Topics: Anti-Inflammatory Agents; Antineoplastic Agents, Phytogenic; Biopsy; Delayed Diagnosis; Disease Prog | 2017 |
Adult-Onset Still's Disease: Still a Serious Health Problem (a Case Report and Literature Review).
Topics: Abdominal Pain; Arthralgia; Biomarkers; Body Mass Index; Diagnosis, Differential; Exanthema; Female; | 2017 |
[Adult Still's disease: study of a series of 11 cases].
Topics: Adult; Anemia; Diagnosis, Differential; Exanthema; Female; Ferritins; Fever; Humans; Incidence; Infe | 2002 |
7 trials available for prednisone and Exanthema
| Article | Year |
|---|---|
Safety Profile of Ipatasertib Plus Abiraterone vs Placebo Plus Abiraterone in Metastatic Castration-resistant Prostate Cancer.
Topics: Abiraterone Acetate; Antineoplastic Combined Chemotherapy Protocols; Exanthema; Humans; Hyperglycemi | 2023 |
Effectiveness and safety of lower dose prednisone for initial treatment of acute graft-versus-host disease: a randomized controlled trial.
Topics: Acute Disease; Adolescent; Adult; Aged; Child; Child, Preschool; Exanthema; Female; Follow-Up Studie | 2015 |
Association of rash with outcomes in a randomized phase II trial evaluating cetuximab in combination with mitoxantrone plus prednisone after docetaxel for metastatic castration-resistant prostate cancer.
Topics: Adenocarcinoma; Aged; Aged, 80 and over; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; | 2012 |
Randomized, controlled study of the effects of a short course of prednisone on the incidence of rash associated with nevirapine in patients infected with HIV-1.
Topics: CD4 Lymphocyte Count; Drug Administration Schedule; Exanthema; Female; HIV; HIV Infections; Humans; | 2003 |
Double blind, randomized, placebo controlled clinical trial of methotrexate in systemic lupus erythematosus.
Topics: Adult; Arthralgia; Arthritis; Double-Blind Method; Drug Therapy, Combination; Exanthema; Female; Hum | 1999 |
Prevention of nevirapine-associated exanthema using slow dose escalation and/or corticosteroids.
Topics: Anti-HIV Agents; Anti-Inflammatory Agents; Exanthema; HIV Infections; Humans; Nevirapine; Prednisone | 2000 |
Failure of a short-term prednisone regimen to prevent nevirapine-associated rash: a double-blind placebo-controlled trial: the GESIDA 09/99 study.
Topics: Adult; Double-Blind Method; Drug Hypersensitivity; Exanthema; Female; Humans; Male; Middle Aged; Nev | 2001 |
78 other studies available for prednisone and Exanthema
| Article | Year |
|---|---|
Fever and flagellate dermatosis in an otherwise healthy woman.
Topics: Adult; Antirheumatic Agents; Exanthema; Female; Fever; Glucocorticoids; Humans; Interleukin 1 Recept | 2022 |
Development of bullous pemphigoid following radiation therapy combined with nivolumab for renal cell carcinoma: A case report of abscopal toxicities.
Topics: Aged; Antineoplastic Agents, Immunological; Carcinoma, Renal Cell; Doxycycline; Drug-Related Side Ef | 2021 |
Recurrent Rash in an 11-Year-Old Boy With Pericardial and Pleural Effusions.
Topics: Amoxicillin; Chest Pain; Child; Cough; Dyspnea; Exanthema; Humans; Male; Pleural Effusion; Prednison | 2022 |
Leprosy with type 1 reaction in a patient from Ontario, Canada without recent travel misdiagnosed as vasculitic neuropathy: a case report.
Topics: Aged, 80 and over; Arthritis, Rheumatoid; Delayed Diagnosis; Diagnostic Errors; Exanthema; Humans; L | 2023 |
A mysterious rash around surgical wounds.
Topics: Adolescent; Anti-Inflammatory Agents; Dermatitis, Contact; Exanthema; Humans; Male; Prednisone; Prur | 2020 |
24-year-old man • prednisone therapy for nephrotic syndrome • diffuse maculopapular rash • pruritis • Dx?
Topics: Exanthema; Glucocorticoids; Humans; Male; Nephrotic Syndrome; Prednisone; Pruritus; Young Adult | 2020 |
Kikuchi disease with cutaneous involvement complicated by features of hemophagocytic lymphohistiocytosis.
Topics: Adult; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Biopsy; Bone Marrow; Diagn | 2021 |
Cover image: Intralymphatic histiocytosis with giant blanching violaceous plaques.
Topics: Aged; Drug Therapy, Combination; Exanthema; Histiocytosis; Humans; Immunoglobulins, Intravenous; Mal | 2017 |
Acute Flare of Bullous Pemphigus With Pembrolizumab Used for Treatment of Metastatic Urothelial Cancer.
Topics: Acute Disease; Antibodies, Monoclonal, Humanized; Antineoplastic Agents, Immunological; Disease Prog | 2018 |
Linear IgA bullous dermatosis: A rare manifestation of vancomycin hypersensitivity.
Topics: Aged, 80 and over; Allergens; Anti-Bacterial Agents; Antibiotic Prophylaxis; Biopsy; Drug Hypersensi | 2018 |
Abrupt generalized pustules in patients with rheumatoid arthritis and interstitial lung disease.
Topics: Acute Generalized Exanthematous Pustulosis; Adult; Arthritis, Rheumatoid; Biopsy; Chromones; Cyclosp | 2018 |
Koebner Phenomenon in Juvenile Dermatomyositis.
Topics: Adolescent; Anti-Inflammatory Agents; Antirheumatic Agents; Biopsy; Creatine Kinase; Dermatologic Ag | 2018 |
Case of lamotrigine-induced drug adverse reaction under tocilizumab treatment with clinical and virological features of drug-induced hypersensitivity syndrome.
Topics: Adult; Antibodies, Monoclonal, Humanized; Anticonvulsants; Arthritis, Rheumatoid; Biopsy; C-Reactive | 2018 |
Adult Henolch-Schonlein purpura: multiorgan failure in the setting of a purpuric rash.
Topics: Aged; Anti-Inflammatory Agents; Exanthema; Humans; IgA Vasculitis; Immunoglobulin A; Lower Extremity | 2018 |
Leprosy after interleukin 6 inhibitor therapy in a patient with rheumatoid arthritis.
Topics: Antibodies, Monoclonal, Humanized; Arthritis, Rheumatoid; Dapsone; Exanthema; Female; Humans; Lepros | 2019 |
Acute generalized exanthematous pustulosis induced by paroxetine in an adolescent girl.
Topics: Adolescent; Drug Eruptions; Exanthema; Female; Glucocorticoids; Humans; Paroxetine; Prednisone; Sele | 2013 |
Death due to eosinophilic necrotizing myocarditis despite steroid treatment.
Topics: Adolescent; Amoxicillin; Anti-Bacterial Agents; Cardiomegaly; Eosinophilia; Exanthema; Focal Infecti | 2013 |
Severe thrombocytopenia and dermonecrosis after loxosceles spider bite in a 3-year-old child.
Topics: Animals; Anti-Bacterial Agents; Brown Recluse Spider; Child, Preschool; Exanthema; Female; Humans; N | 2013 |
"Blueberry muffin" rash and large right thigh mass: a unique presentation of Langerhans cell histiocytosis.
Topics: Biopsy; Calcinosis; Drug Therapy, Combination; Exanthema; Hematopoiesis, Extramedullary; Histiocytos | 2013 |
Case records of the Massachusetts General Hospital. Case 28-2014. A 39-year-old man with a rash, headache, fever, nausea, and photophobia.
Topics: Adult; Animals; Chronic Disease; Diagnosis, Differential; Eosinophilia; Exanthema; Glucocorticoids; | 2014 |
Abdominal pain, rash, and arthritis.
Topics: Abdominal Pain; Adolescent; Anti-Inflammatory Agents; Antirheumatic Agents; Arthritis; Azathioprine; | 2015 |
[Suspected itchy rash secondary to lenalidomide].
Topics: Aged; Angiogenesis Inhibitors; Anti-Inflammatory Agents; Drug Eruptions; Exanthema; Female; Humans; | 2014 |
A 2½-Year-Old Girl With a Diffuse Erythematous Rash and Fever.
Topics: Child, Preschool; Diagnosis, Differential; Drug Hypersensitivity Syndrome; Erythema; Exanthema; Fema | 2015 |
[DRESS syndrome: Report of nine cases].
Topics: Adolescent; Adult; Aged; Carbamazepine; Dexamethasone; Drug Hypersensitivity Syndrome; Eosinophilia; | 2015 |
Oral ulcerations after placement of orthodontic braces and skin pustules after laser hair removal: novel inducers of pathergy reactions in new-onset Behçet's disease.
Topics: Adult; Anti-Inflammatory Agents; Behcet Syndrome; Colchicine; Exanthema; Hair Removal; Humans; Male; | 2016 |
Elderly Female With Perianal Rash.
Topics: Administration, Oral; Aged; Anti-Inflammatory Agents; Anus Diseases; Buttocks; Diabetes Mellitus, Ty | 2016 |
Generalized rash follows ankle ulceration.
Topics: Adult; Ankle Injuries; Exanthema; Glucocorticoids; Histamine Antagonists; Humans; Male; Naproxen; Pr | 2016 |
Mildly pruritic palmar rash.
Topics: Azithromycin; Exanthema; Humans; Male; Middle Aged; Practice Guidelines as Topic; Prednisone; Prurig | 2016 |
Fever and rash.
Topics: Anti-Inflammatory Agents; Child; Ehrlichia chaffeensis; Ehrlichiosis; Exanthema; Fatigue; Fever; Hum | 2008 |
Clinical features and prognosis of adult-onset still's disease: 61 cases from China.
Topics: Adult; Arthritis; Asian People; Blood Sedimentation; Cause of Death; China; Exanthema; Female; Fever | 2009 |
Pralatrexate-induced tumor cell apoptosis in the epidermis of a patient with HTLV-1 adult T-cell lymphoma/leukemia causing skin erosions.
Topics: Adult; Aminopterin; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; | 2009 |
Development of classic dermatomyositis rash years after diagnosis of juvenile polymyositis.
Topics: Anti-Inflammatory Agents; Child; Dermatomyositis; Disease Progression; Drug Therapy, Combination; Ex | 2009 |
A child with ulcerative lesions and whitish plaques on the tongue.
Topics: Acyclovir; Antiviral Agents; Child; Drug Therapy, Combination; Exanthema; Facial Paralysis; Glucocor | 2010 |
Interactive medical case. A rash hypothesis.
Topics: Acetates; Adult; Anti-Inflammatory Agents; Cromolyn Sodium; Cyclopropanes; Diarrhea; Drug Therapy, C | 2010 |
[Rash, fever, eosinophilia and elevated liver enzymes. DRESS syndrome (drug reaction or rash with eosinophilia and systemic symptoms)].
Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Murine-Derived; Antineoplastic Combined Chemotherapy | 2010 |
Clinical problem-solving. A rash hypothesis.
Topics: Adult; Biopsy; Blood Cell Count; Bone Marrow; Colon; Diagnosis, Differential; Diarrhea; Drug Therapy | 2010 |
A case of Crohn's disease complicated by adult onset Still's disease.
Topics: Adult; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Crohn Disease; Exanthema; | 2010 |
A tale of two rashes.
Topics: Aged; Antihypertensive Agents; Azathioprine; Complement C4; Cryoglobulinemia; Diagnosis, Differentia | 2011 |
Early-onset childhood sarcoidosis with incidental multiple enchondromatosis.
Topics: Administration, Oral; Anti-Inflammatory Agents; Arthritis; Child, Preschool; Diagnosis, Differential | 2012 |
A childlike presentation?
Topics: Abdominal Pain; Adult; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Arthralgia | 2012 |
Corticosteroids and monocytosis.
Topics: Aged, 80 and over; Exanthema; Glucocorticoids; Humans; Leukocyte Count; Male; Methotrexate; Monocyte | 2012 |
Drug reaction with eosinophilia and systemic symptoms (DRESS) in a patient taking sitagliptin.
Topics: Acute Kidney Injury; Aged; Back; Diabetes Mellitus, Type 2; Dipeptidyl-Peptidase IV Inhibitors; Ear; | 2012 |
Nevirapine, prednisone and rash.
Topics: Diphenhydramine; Exanthema; HIV Infections; Humans; Nevirapine; Prednisone | 2000 |
[VASCULAR AND CONNECTIVE TISSUE CHANGES OF SUSPECTED ALLERGIC ORIGIN].
Topics: Connective Tissue; Drug Eruptions; Exanthema; Hypersensitivity; Inguinal Canal; Penicillins; Prednis | 1964 |
POLYCYTHAEMIA RUBRA VERA: SKIN ERUPTION UNDIAGNOSED.
Topics: Diagnosis; Exanthema; Humans; Pathology; Polycythemia Vera; Prednisone; Skin Diseases | 1965 |
Increased rates of early adverse reaction to azathioprine in patients with Crohn's disease compared to autoimmune hepatitis: a tertiary referral center experience.
Topics: Acute Disease; Adult; Anti-Inflammatory Agents; Arthralgia; Azathioprine; Crohn Disease; Disease Sus | 2005 |
Cough, wheezing, and rash in a patient with a history of allergic bronchopulmonary aspergillosis.
Topics: Adult; Aspergillosis, Allergic Bronchopulmonary; Asthma; Bronchial Spasm; Cough; Exanthema; Female; | 2005 |
Skin rash and muscle weakness.
Topics: Dermatomyositis; Exanthema; Female; Glucocorticoids; Humans; Middle Aged; Muscle Weakness; Prednison | 2005 |
Case records of the Massachusetts General Hospital. Case 31-2005. A 60-year-old man with skin lesions and renal insufficiency.
Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Murine-Derived; Creatinine; Cryoglobulinemia; Diagno | 2005 |
Purpura followed by proteinuria in a 7-year-old girl.
Topics: Angiotensin-Converting Enzyme Inhibitors; Anti-Inflammatory Agents; Biopsy; Child; Exanthema; Female | 2005 |
Skin lesions induced by bortezomib.
Topics: Antineoplastic Agents; Boronic Acids; Bortezomib; Cetirizine; Combined Modality Therapy; Dexamethaso | 2005 |
[Efficacy of rituximab-containing regimens on indolent B-cell lymphoma--a report of 34 cases].
Topics: Adult; Aged; Antibodies, Monoclonal; Antibodies, Monoclonal, Murine-Derived; Antineoplastic Agents; | 2006 |
Rash and fever.
Topics: Adult; Anti-Inflammatory Agents; Conjunctivitis, Bacterial; Diagnosis, Differential; Emergency Medic | 2006 |
Lack of cross-reactivity between 5-aminosalicylic acid-based drugs: a case report and review of the literature.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Crohn Disease; Cross Reactions; Drug Hypersensitivit | 2006 |
57-year-old Asian-American man with Kikuchi's disease.
Topics: Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Arthralgia; Asian; Biopsy; Diagno | 2006 |
Visual diagnosis: an adolescent who has fever, joint pain, a rash, and "blacking out" episodes.
Topics: Adolescent; Arthralgia; Cerebellum; Drug Therapy, Combination; Exanthema; Female; Ferrous Compounds; | 2007 |
Amyopathic dermatomyositis--an uncommon presentation of dermatomyositis.
Topics: Adult; Arthralgia; Cyclosporine; Dermatologic Agents; Dermatomyositis; Exanthema; Glucocorticoids; H | 2007 |
[Fever and maculopapular exanthema as first manifestation of lymphoma].
Topics: Aged; Antibodies, Monoclonal; Antibodies, Monoclonal, Murine-Derived; Antineoplastic Agents; Antineo | 2007 |
Rash and GI symptoms on day +36.
Topics: Adult; Cytomegalovirus Infections; Diarrhea; Exanthema; Glucocorticoids; Graft vs Host Disease; Huma | 2007 |
[Gianotti-Crosti syndrome in the course of juvenile acute hepatitis B infection].
Topics: Acrodermatitis; Child, Preschool; Exanthema; Female; Hepatitis B; Humans; Infant; Prednisone; Syndro | 1981 |
Acute generalized exanthematous pustulosis.
Topics: Adrenal Cortex Hormones; Adult; Antitussive Agents; Codeine; Diagnosis, Differential; Drug Eruptions | 1995 |
[A case of acute sarcoidosis].
Topics: Acute Disease; Adult; Arthralgia; Diagnosis, Differential; Exanthema; Female; Humans; Prednisone; Re | 1996 |
Churg-Strauss syndrome associated with zafirlukast.
Topics: Anti-Asthmatic Agents; Anti-Inflammatory Agents; Arthralgia; Asthma; Churg-Strauss Syndrome; Exanthe | 1998 |
[Pseudo-periodic disease with hyperimmunoglobulinemia D: a never-ending story with probable prenatal onset].
Topics: Anti-Inflammatory Agents; Arthritis; Child; Diagnosis, Differential; Exanthema; Familial Mediterrane | 1998 |
Photo quiz. Back rash.
Topics: Acne Vulgaris; Adult; Back; Exanthema; Glucocorticoids; Humans; Male; Prednisone; Purpura, Thrombocy | 1999 |
Levamisole vs. cyclophosphamide for frequently-relapsing steroid-dependent nephrotic syndrome.
Topics: Adjuvants, Immunologic; Child; Child, Preschool; Cyclophosphamide; Drug Costs; Exanthema; Female; Gl | 2001 |
Psoralen and ultraviolet A irradiation (PUVA) as therapy for steroid-resistant cutaneous acute graft-versus-host disease.
Topics: Acute Disease; Adolescent; Adult; Anemia, Refractory, with Excess of Blasts; Bone Marrow Transplanta | 2002 |
Varicella followed by glomerulonephritis. Treatment with corticosteroids and azathioprine resulting in recurrence of varicella.
Topics: Azathioprine; Chickenpox; Child, Preschool; Exanthema; Gastrointestinal Hemorrhage; Glomerulonephrit | 1975 |
Acute reversible blindness with papillomacular rash, hearing loss and miningismus.
Topics: Blindness; Dexamethasone; Drug Therapy, Combination; Exanthema; Female; Hearing Disorders; Humans; M | 1975 |
The diagnostic features of SLE.
Topics: Adult; Alopecia; Blood Chemical Analysis; Exanthema; Female; Humans; Lupus Erythematosus, Systemic; | 1989 |
[Toxic encephaloenteritis-epidemic caused by adenoviruses of type 3].
Topics: Adenoviridae; Adenoviridae Infections; Analgesics; Anti-Bacterial Agents; Child; Child, Preschool; C | 1968 |
[Morbilliform exanthema in leukoses under chemotherapy].
Topics: Adolescent; Adult; Daunorubicin; Diagnosis, Differential; Exanthema; Humans; Leukemia, Lymphoid; Mal | 1972 |
[Cutaneous miliary sarcoidosis in a child].
Topics: Diagnosis, Differential; Exanthema; Humans; Infant; Isoniazid; Male; Prednisone; Sarcoidosis; Skin T | 1972 |
[Nephrotic syndrome due to penicillamine (author's transl)].
Topics: Adult; Arthritis, Rheumatoid; Biopsy; Exanthema; Female; Humans; Immunoglobulin G; Kidney; Nephrotic | 1973 |
Blood lymphoblast proliferation in vivo in cutaneous drug hypersensitivity reactions.
Topics: Blood Cell Count; Carbamazepine; Chlorpromazine; Drug Hypersensitivity; Exanthema; Humans; Lymphocyt | 1974 |
[Problem of eosinophilic leukemia with skin involvement].
Topics: Chronic Disease; Cyclophosphamide; Eosinophils; Exanthema; Female; Humans; Leukemia; Male; Prednison | 1970 |
[Wissler's allergic subsepsis or Hegglin's hyperergic periodic fever].
Topics: Antineoplastic Agents; Child; Exanthema; Female; Humans; Hypersensitivity; Immunosuppressive Agents; | 1970 |
[A case of generalized drug exanthema following local application of neomycin, caused by dermal hypersensitization].
Topics: Adult; Anti-Bacterial Agents; Drug Hypersensitivity; Environmental Exposure; Erysipelas; Exanthema; | 1968 |