prednisone has been researched along with Esophageal and Gastric Varices in 11 studies
Prednisone: A synthetic anti-inflammatory glucocorticoid derived from CORTISONE. It is biologically inert and converted to PREDNISOLONE in the liver.
prednisone : A synthetic glucocorticoid drug that is particularly effective as an immunosuppressant, and affects virtually all of the immune system. Prednisone is a prodrug that is converted by the liver into prednisolone (a beta-hydroxy group instead of the oxo group at position 11), which is the active drug and also a steroid.
Esophageal and Gastric Varices: Dilated blood vessels in the ESOPHAGUS or GASTRIC FUNDUS that shunt blood from the portal circulation (PORTAL SYSTEM) to the systemic venous circulation. Often they are observed in individuals with portal hypertension (HYPERTENSION, PORTAL).
| Excerpt | Relevance | Reference |
|---|---|---|
| "The prevalence of gastroesophageal varices and gastrointestinal hemorrhage was determined in 124 patients with severe chronic active liver disease (CALD) receiving prednisone and followed regularly for up to 10 yr." | 7.66 | Development and early prognosis of esophageal varices in severe chronic active liver disease (CALD) treated with prednisone. ( Czaja, AJ; Summerskill, WH; Wolf, AM, 1979) |
| " Prednisone reduced the occurrence rate of varices, bleeding from varices, and death from bleeding varices in nonalcoholic females without ascites, 40% of whom fulfilled the histologic criteria of chronic active hepatitis." | 5.05 | Aspects of the natural history of gastrointestinal bleeding in cirrhosis and the effect of prednisone. ( Christensen, E; Fauerholdt, L; Juhl, E; Poulsen, H; Schlichting, P; Tygstrup, N, 1981) |
| "The prevalence of gastroesophageal varices and gastrointestinal hemorrhage was determined in 124 patients with severe chronic active liver disease (CALD) receiving prednisone and followed regularly for up to 10 yr." | 3.66 | Development and early prognosis of esophageal varices in severe chronic active liver disease (CALD) treated with prednisone. ( Czaja, AJ; Summerskill, WH; Wolf, AM, 1979) |
| "A 60-yr-old white woman with CREST syndrome (calcinosis cutis, Raynaud's phenomenon, esophageal involvement, sclerodactyly, telangectasia), idiophatic portal hypertension and esophageal varices presented with a 2-month history of bone pain and severe anemia, requiring erythrocyte transfusion every 5-7 d." | 1.33 | Bone marrow necrosis successfully treated with corticosteroid. ( Brandão-Neto, RA; Ramos, RG; Santana, AN; Zanandrea, EF, 2005) |
| "Treatment with prednisone resulted in relief of lumbar and flank pain a well as in prevention of further digestive tract hemorrhage." | 1.29 | [Retroperitoneal fibrosis and portal hypertension]. ( Bernasconi, S; Pedrinis, E; Realini, S; Reiner, M, 1993) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 7 (63.64) | 18.7374 |
| 1990's | 2 (18.18) | 18.2507 |
| 2000's | 2 (18.18) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| STAUFFER, MH | 1 |
| SAUER, WG | 1 |
| DEARING, WH | 1 |
| BAGGENSTOSS, AH | 1 |
| Santana, AN | 1 |
| Ramos, RG | 1 |
| Zanandrea, EF | 1 |
| Brandão-Neto, RA | 1 |
| Silver, R | 1 |
| Christensen, E | 1 |
| Fauerholdt, L | 1 |
| Schlichting, P | 1 |
| Juhl, E | 1 |
| Poulsen, H | 1 |
| Tygstrup, N | 1 |
| Realini, S | 1 |
| Reiner, M | 1 |
| Bernasconi, S | 1 |
| Pedrinis, E | 1 |
| Melissant, CF | 1 |
| Smith, SJ | 1 |
| Kazzaz, BA | 1 |
| Demedts, M | 1 |
| Czaja, AJ | 1 |
| Wolf, AM | 1 |
| Summerskill, WH | 1 |
| Murray-Lyon, IM | 2 |
| Stern, RB | 2 |
| Williams, R | 2 |
| Grossman, JA | 1 |
| McDermott, WV | 1 |
| Pfleiderer, T | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A New Technique to Enhance Detection of Small Esophageal Varices by PillCam ESO Capsule Endoscopy[NCT00911131] | Phase 3 | 0 participants (Actual) | Interventional | Withdrawn (stopped due to Loss of funding) | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
3 trials available for prednisone and Esophageal and Gastric Varices
| Article | Year |
|---|---|
Aspects of the natural history of gastrointestinal bleeding in cirrhosis and the effect of prednisone.
Topics: Clinical Trials as Topic; Esophageal and Gastric Varices; Female; Gastrointestinal Hemorrhage; Hepat | 1981 |
Controlled trial of prednisone and azathioprine in active chronic hepatitis.
Topics: Adult; Alkaline Phosphatase; Antibodies; Antibodies, Antinuclear; Aspartate Aminotransferases; Azath | 1973 |
Controlled trial of corticosteroids and azathioprine in active chronic hepatitis.
Topics: Azathioprine; Chronic Disease; Esophageal and Gastric Varices; gamma-Globulins; Hepatitis; Humans; P | 1973 |
8 other studies available for prednisone and Esophageal and Gastric Varices
| Article | Year |
|---|---|
THE SPECTRUM OF CHOLESTATIC HEPATIC DISEASE.
Topics: Adolescent; Alkaline Phosphatase; Aspartate Aminotransferases; Bile Duct Neoplasms; Bilirubin; Blood | 1965 |
Bone marrow necrosis successfully treated with corticosteroid.
Topics: Adrenal Cortex Hormones; Bone Marrow; CREST Syndrome; Esophageal and Gastric Varices; Female; Humans | 2005 |
Current treatment of myelofibrosis.
Topics: Blood Transfusion; Bone Marrow Transplantation; Clinical Trials as Topic; Dexamethasone; Disease Man | 2005 |
[Retroperitoneal fibrosis and portal hypertension].
Topics: Aged; Esophageal and Gastric Varices; Gastrointestinal Hemorrhage; Humans; Hypertension, Portal; Mal | 1993 |
Bleeding varices due to portal hypertension in sarcoidosis. Favorable effect of propranolol and prednisone.
Topics: Drug Therapy, Combination; Esophageal and Gastric Varices; Gastrointestinal Hemorrhage; Humans; Hype | 1993 |
Development and early prognosis of esophageal varices in severe chronic active liver disease (CALD) treated with prednisone.
Topics: Adolescent; Adult; Aged; Chronic Disease; Esophageal and Gastric Varices; Female; Follow-Up Studies; | 1979 |
Paroxysmal nocturnal hemoglobinuria associated with hepatic and portal venous thrombosis.
Topics: Adult; Age Factors; Anemia, Hemolytic, Autoimmune; Budd-Chiari Syndrome; Diagnostic Errors; Erythroc | 1974 |
[Current problems in clinical aspects and therapy of liver cirrhosis].
Topics: Adult; Aged; Ascites; Esophageal and Gastric Varices; Female; Germany, West; Glucocorticoids; Hepati | 1970 |