prednisone has been researched along with Drug Withdrawal Symptoms in 87 studies
Prednisone: A synthetic anti-inflammatory glucocorticoid derived from CORTISONE. It is biologically inert and converted to PREDNISOLONE in the liver.
prednisone : A synthetic glucocorticoid drug that is particularly effective as an immunosuppressant, and affects virtually all of the immune system. Prednisone is a prodrug that is converted by the liver into prednisolone (a beta-hydroxy group instead of the oxo group at position 11), which is the active drug and also a steroid.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The theraprutic efficacy of inhaled beclomethasone dipropionate and inhaled betamethasone valerate in chronic asthma has been studied in 14 treatment centres in 158 patients who had previously been taking prednisone tablets regularly." | 9.04 | A controlled trial of inhaled corticosteroids in patients receiving Prednisone tablets for asthma. ( , 1976) |
| " The heavy proteinuria exhibited a striking steroid-dependent course during a three-year period of time, with ten relapses occurring whenever attempts were made to withdraw prednisone therapy." | 7.67 | Steroid-dependent nephrotic syndrome in lupus nephritis. Response to chlorambucil. ( Abuelo, JG; Esparza, AR; Garella, S, 1984) |
| "Eighty percent of 26 steroid-dependent, chronically asthmatic adults eliminated oral steroid dosage after 12 weeks of treatment with triamcinolone acetonide aerosol (800 micrograms/day)." | 7.66 | Long-term triamcinolone acetonide aerosol treatment in adult patients with chronic bronchial asthma. ( Golub, JR, 1980) |
| "To examine whether sustained minimal manifestation status (MMS) with complete withdrawal of prednisone is better achieved in thymectomized patients with myasthenia gravis (MG)." | 5.34 | Minimal manifestation status and prednisone withdrawal in the MGTX trial. ( Aban, IB; Amato, AA; Antonini, G; Barboi, AC; Barohn, RJ; Benatar, M; Beydoun, SR; Buckley, C; Cea, G; Chalk, CH; Ciafaloni, E; Conwit, R; Cutter, GR; Dias-Tosta, E; Evoli, A; Heckmann, JM; Jackson, CE; Kaminski, HJ; Katirji, B; King, JO; Kissel, JT; Kostera-Pruszczyk, A; Kuo, HC; Lecky, BRF; Lee, I; Massey, JM; McPherson, T; Minisman, G; Mozaffar, T; Nix, W; Oger, J; Pascuzzi, RM; Pulley, MT; Rivner, MH; Shaibani, AI; Sonett, JR; Ströbel, P; Sussman, J; Tandan, R; Verschuuren, JJG; Vincent, A; Waddington-Cruz, M; Werneck, LC; Witoonpanich, R; Wolfe, GI; Yoshikawa, H, 2020) |
| " In this study, adrenal function and signs and symptoms of adrenal insufficiency were prospectively assessed in children with acute lymphoblastic leukemia (ALL) after induction treatment including high-dose prednisone (PDN) or dexamethasone (DXM)." | 5.13 | Adrenal axis function after high-dose steroid therapy for childhood acute lymphoblastic leukemia. ( Barisone, E; Bertorello, N; Corrias, A; Einaudi, S; Farinasso, L; Masera, N; Pastore, G; Riva, F; Rizzari, C; Saracco, P; Villa, A, 2008) |
| "One hundred and twenty patients of idiopathic nephrotic syndrome sensitive to prednisone treatment were divided into two groups randomly." | 5.09 | [Assessment on application of Chinese herbs in process of corticosterone reduction in nephrotic syndrome]. ( Guo, M; Xiao, Q; Zhao, X, 2000) |
| "The theraprutic efficacy of inhaled beclomethasone dipropionate and inhaled betamethasone valerate in chronic asthma has been studied in 14 treatment centres in 158 patients who had previously been taking prednisone tablets regularly." | 5.04 | A controlled trial of inhaled corticosteroids in patients receiving Prednisone tablets for asthma. ( , 1976) |
| " The heavy proteinuria exhibited a striking steroid-dependent course during a three-year period of time, with ten relapses occurring whenever attempts were made to withdraw prednisone therapy." | 3.67 | Steroid-dependent nephrotic syndrome in lupus nephritis. Response to chlorambucil. ( Abuelo, JG; Esparza, AR; Garella, S, 1984) |
| "A patient is described who had high spiking fever following a changeover from daily to alternate-day prednisone therapy." | 3.67 | Fever on drug-free day of alternate-day steroid therapy. ( Semel, JD, 1984) |
| "Eighty percent of 26 steroid-dependent, chronically asthmatic adults eliminated oral steroid dosage after 12 weeks of treatment with triamcinolone acetonide aerosol (800 micrograms/day)." | 3.66 | Long-term triamcinolone acetonide aerosol treatment in adult patients with chronic bronchial asthma. ( Golub, JR, 1980) |
| "Chronic migraine (CM) patients frequently overuse symptomatic medications (SM)." | 2.71 | Out-patient detoxification in chronic migraine: comparison of strategies. ( Krymchantowski, AV; Moreira, PF, 2003) |
| "Children with acute lymphoblastic leukemia (ALL) receive as part of induction therapy a 4-week course of high-dose glucocorticoid, which is either abruptly discontinued or shortly tapered." | 2.71 | Steroid withdrawal syndrome during steroid tapering in childhood acute lymphoblastic leukemia: a controlled study comparing prednisone versus dexamethasone in induction phase. ( Altare, F; Barisone, E; Bertorello, N; Corrias, A; Einaudi, S; Farinasso, L; Pastore, G; Saracco, P, 2005) |
| "Patients with quiescent systemic lupus erythematosus who are taking hydroxychloroquine are less likely to have a clinical flare-up if they are maintained on the drug." | 2.67 | A randomized study of the effect of withdrawing hydroxychloroquine sulfate in systemic lupus erythematosus. ( , 1991) |
| "Drug-induced vasculitis is an inflammation of blood vessels caused by the use of various pharmaceutical agents." | 2.48 | Drug-induced vasculitis: a clinical and pathological review. ( Martinović Kaliterna, D; Radić, J; Radić, M, 2012) |
| "A case report of a 51-year-old man with substance dependence on prednisone is reported." | 2.40 | Chemical dependence involving glucocorticoids. ( Brown, ES, 1997) |
| "Abiraterone acetate (AA) is an androgen receptor axis inhibitor, indicated together with prednisone, for metastatic castration-resistant prostate cancer." | 1.48 | Long-term abiraterone withdrawal syndrome. ( Campins, L; Font, A; Lianes, P; Marin, S; Miarons, M; Querol, R, 2018) |
| "Relapse of type 1 autoimmune hepatitis after drug withdrawal may relate to incomplete histological improvement during corticosteroid therapy and/or persistence of pathogenic mechanisms." | 1.32 | Histological features associated with relapse after corticosteroid withdrawal in type 1 autoimmune hepatitis. ( Carpenter, HA; Czaja, AJ, 2003) |
| " Because of the significant adverse effects with long-term use of steroids, especially the damage of the hypothalamus-pituitary-adrenocortical(HPA) axis, long-term steroids administration should be avoided or withdrawn gradually." | 1.29 | [Investigation of treating steroids dependent asthmatic patients with kidney-tonifying herbs and high dose beclomethasone dipropionate aerosol]. ( Dong, JC; Shen, ZY; Shi, ZY, 1994) |
| "We treated two patients with Crohn's disease and one patient with ulcerative colitis who developed headache, papilledema, and intracranial hypertension (pseudotumor cerebri) during corticosteroid withdrawal." | 1.29 | Pseudotumor cerebri associated with corticosteroid withdrawal in inflammatory bowel disease. ( Bienfang, DC; Kay, MD; Liu, GT; Schatz, NJ, 1994) |
| " The first patient suffered from ulcerative colitis and developed Guillain-Barré syndrome when the steroid dosage was being tapered." | 1.27 | Appearance of Guillain-Barré syndrome in patients during corticosteroid treatment. ( Abramsky, O; Steiner, I; Wirguin, I, 1986) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 36 (41.38) | 18.7374 |
| 1990's | 27 (31.03) | 18.2507 |
| 2000's | 15 (17.24) | 29.6817 |
| 2010's | 8 (9.20) | 24.3611 |
| 2020's | 1 (1.15) | 2.80 |
| Authors | Studies |
|---|---|
| Lee, I | 1 |
| Kuo, HC | 1 |
| Aban, IB | 1 |
| Cutter, GR | 1 |
| McPherson, T | 1 |
| Kaminski, HJ | 1 |
| Sussman, J | 1 |
| Ströbel, P | 1 |
| Oger, J | 1 |
| Cea, G | 1 |
| Heckmann, JM | 1 |
| Evoli, A | 1 |
| Nix, W | 1 |
| Ciafaloni, E | 1 |
| Antonini, G | 1 |
| Witoonpanich, R | 1 |
| King, JO | 1 |
| Beydoun, SR | 1 |
| Chalk, CH | 1 |
| Barboi, AC | 1 |
| Amato, AA | 1 |
| Shaibani, AI | 1 |
| Katirji, B | 1 |
| Lecky, BRF | 1 |
| Buckley, C | 1 |
| Vincent, A | 1 |
| Dias-Tosta, E | 1 |
| Yoshikawa, H | 1 |
| Waddington-Cruz, M | 1 |
| Pulley, MT | 1 |
| Rivner, MH | 1 |
| Kostera-Pruszczyk, A | 1 |
| Pascuzzi, RM | 1 |
| Jackson, CE | 1 |
| Verschuuren, JJG | 1 |
| Massey, JM | 1 |
| Kissel, JT | 1 |
| Werneck, LC | 1 |
| Benatar, M | 1 |
| Barohn, RJ | 1 |
| Tandan, R | 1 |
| Mozaffar, T | 1 |
| Conwit, R | 1 |
| Minisman, G | 1 |
| Sonett, JR | 1 |
| Wolfe, GI | 1 |
| Marin, S | 1 |
| Querol, R | 1 |
| Campins, L | 1 |
| Miarons, M | 1 |
| Font, A | 1 |
| Lianes, P | 1 |
| Gable, M | 1 |
| Depry, D | 1 |
| Ribeiro, RT | 1 |
| Carriço, LA | 1 |
| Bezerra, ML | 1 |
| Villa, TR | 1 |
| Pereira, MM | 1 |
| Matas, AJ | 1 |
| Armstrong, AJ | 1 |
| George, DJ | 1 |
| Neidert, S | 1 |
| Schuetz, P | 1 |
| Mueller, B | 1 |
| Christ-Crain, M | 1 |
| Padiyar, A | 1 |
| Augustine, JJ | 1 |
| Bodziak, KA | 1 |
| Aeder, M | 1 |
| Schulak, JA | 3 |
| Hricik, DF | 1 |
| Radić, M | 1 |
| Martinović Kaliterna, D | 1 |
| Radić, J | 1 |
| El Sanhouri, A | 1 |
| Sisk, RA | 1 |
| Petersen, MR | 1 |
| Brackmann, F | 1 |
| Dörr, HG | 1 |
| Bartram, CR | 1 |
| Hinderhofer, K | 1 |
| Holter, W | 1 |
| Langer, T | 1 |
| Guo, ZX | 1 |
| Yu, WQ | 1 |
| Song, BH | 1 |
| Czaja, AJ | 1 |
| Carpenter, HA | 1 |
| Barlow, AD | 1 |
| Clarke, GA | 1 |
| Kelly, MJ | 1 |
| Krymchantowski, AV | 2 |
| Moreira, PF | 1 |
| Saracco, P | 2 |
| Bertorello, N | 2 |
| Farinasso, L | 2 |
| Einaudi, S | 2 |
| Barisone, E | 2 |
| Altare, F | 1 |
| Corrias, A | 2 |
| Pastore, G | 2 |
| Towne, LM | 1 |
| Masera, N | 1 |
| Rizzari, C | 1 |
| Villa, A | 1 |
| Riva, F | 1 |
| Pageler, L | 1 |
| Katsarava, Z | 1 |
| Diener, HC | 1 |
| Limmroth, V | 1 |
| Pezner, RD | 1 |
| Bertrand, M | 1 |
| Cecchi, GR | 1 |
| Paladugu, RR | 1 |
| Kendregan, BA | 1 |
| Abuelo, JG | 1 |
| Esparza, AR | 1 |
| Garella, S | 1 |
| Semel, JD | 1 |
| Golub, JR | 1 |
| Ozaki, A | 1 |
| Iwasaki, Y | 1 |
| Miyajima, T | 1 |
| First, MR | 1 |
| Munda, R | 1 |
| Kant, KS | 1 |
| Fidler, JP | 1 |
| Alexander, JW | 1 |
| Dixon, RB | 1 |
| Christy, NP | 1 |
| Korula, J | 1 |
| Dong, JC | 1 |
| Shi, ZY | 1 |
| Shen, ZY | 1 |
| Roberti, I | 1 |
| Reisman, L | 2 |
| Lieberman, KV | 2 |
| Burrows, L | 2 |
| Heim-Duthoy, KL | 1 |
| Chitwood, KK | 1 |
| Tortorice, KL | 1 |
| Massy, ZA | 1 |
| Kasiske, BL | 2 |
| Barrier, JH | 1 |
| Larrose, C | 1 |
| Magadur/Joly, G | 1 |
| Hamidou, M | 1 |
| Liu, GT | 1 |
| Kay, MD | 1 |
| Bienfang, DC | 1 |
| Schatz, NJ | 1 |
| Sandborn, WJ | 1 |
| Hay, JE | 1 |
| Porayko, MK | 1 |
| Gores, GJ | 1 |
| Steers, JL | 1 |
| Krom, RA | 1 |
| Wiesner, RH | 1 |
| Ye, RG | 1 |
| Frierson, JH | 1 |
| May, CM | 1 |
| Ingulli, E | 1 |
| Tejani, A | 1 |
| Markell, M | 1 |
| Hricik, DE | 2 |
| Seliga, RM | 1 |
| Fleming-Brooks, S | 1 |
| Bartucci, MR | 2 |
| Suárez Ortega, S | 1 |
| Rodríguez Perdomo, E | 1 |
| Gabari Ferrus, P | 1 |
| Parrilla Díaz, J | 1 |
| Bouma, GJ | 1 |
| Hollander, DA | 1 |
| van der Meer-Prins, EM | 1 |
| van Bree, SP | 1 |
| van Rood, JJ | 1 |
| van der Woude, FJ | 1 |
| Claas, FH | 1 |
| Brown, ES | 1 |
| Vignes, S | 1 |
| Vidailhet, M | 1 |
| Dormont, D | 1 |
| Soulié, J | 1 |
| Wechsler, B | 1 |
| Dunn, TB | 1 |
| Asolati, M | 1 |
| Holman, DM | 1 |
| Raofi, V | 1 |
| Jovanovic, B | 1 |
| Pollak, R | 1 |
| Benedetti, E | 1 |
| Frosi, A | 1 |
| Foresi, A | 1 |
| Bozzoni, M | 1 |
| Ubbiali, A | 1 |
| Vezzoli, F | 1 |
| Krasner, AS | 1 |
| Bili, A | 1 |
| Condemi, JJ | 1 |
| Bottone, SM | 1 |
| Ryan, CK | 1 |
| Barbosa, JS | 1 |
| Wang, X | 1 |
| Xiao, Q | 1 |
| Zhao, X | 1 |
| Guo, M | 1 |
| DeSilva, CC | 1 |
| Nurse, MC | 1 |
| Vokey, K | 1 |
| Anjum, S | 1 |
| Andany, MA | 1 |
| McClean, JC | 1 |
| Danielson, B | 1 |
| Webb, DR | 1 |
| Storrs, FJ | 1 |
| Imbeau, SA | 1 |
| Mathew, PK | 1 |
| Ballin, JC | 1 |
| Minuk, GY | 1 |
| German, GB | 1 |
| Bernstein, C | 1 |
| Benarroch, A | 1 |
| Gauthier, T | 1 |
| Sekla, L | 1 |
| Eisenlohr, H | 1 |
| Trenkwalder, P | 1 |
| Lydtin, H | 1 |
| Mayes, JT | 1 |
| Robson, SC | 1 |
| Brice, E | 1 |
| van Rensburg, C | 1 |
| Kannemeyer, J | 1 |
| Hift, RJ | 1 |
| Kirsch, RE | 1 |
| Hassanyeh, F | 1 |
| Murray, RB | 1 |
| Rodgers, H | 1 |
| O'Connell, JB | 1 |
| Bristow, MR | 1 |
| Rasmussen, LG | 1 |
| Ratkovec, RM | 1 |
| Gay, WA | 1 |
| Jones, KW | 1 |
| Renlund, DG | 1 |
| Schanzer, H | 1 |
| Steiner, I | 1 |
| Wirguin, I | 1 |
| Abramsky, O | 1 |
| Venkatarangam, SH | 1 |
| Kutcher, SP | 1 |
| Notkin, RM | 1 |
| Stratta, RJ | 1 |
| Armbrust, MJ | 1 |
| Oh, CS | 1 |
| Pirsch, JD | 1 |
| Kalayoglu, M | 1 |
| Sollinger, HW | 1 |
| Belzer, FO | 1 |
| Kabadi, UM | 1 |
| Sultan, IH | 1 |
| Newmark, KJ | 1 |
| Mitra, S | 1 |
| Berman, LB | 1 |
| Jasiński, K | 1 |
| Witoszyński, S | 1 |
| Amatruda, TT | 1 |
| Hurst, MM | 1 |
| D'Esopo, ND | 1 |
| Hamaty, D | 1 |
| Fine, RM | 1 |
| Ansari, ZH | 1 |
| Clark, PA | 1 |
| Maher-Loughnan, GP | 1 |
| Pittman, JG | 1 |
| Batten, JC | 2 |
| Clarke, SW | 2 |
| Gregg, I | 2 |
| Hodson, ME | 2 |
| Maberly, DJ | 1 |
| Gibson, GJ | 1 |
| Butler, AG | 1 |
| Gifford, RH | 1 |
| Morgan, HG | 1 |
| Boulnois, J | 1 |
| Burns-Cox, C | 1 |
| Skrabal, F | 1 |
| Arnot, RN | 1 |
| Joplin, GF | 1 |
| Fraser, TR | 1 |
| Kimball, CP | 1 |
| Hargreave, FE | 1 |
| McCarthy, DS | 1 |
| Pepys, J | 1 |
| Jones, JP | 1 |
| Engleman, EP | 1 |
| Najarian, JS | 1 |
| Kindermann, G | 1 |
| Stephen, JM | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Multi-Center, Single-Blind, Randomized Study Comparing Thymectomy to No Thymectomy in Non-Thymomatous Myasthenia Gravis (MG) Patients Receiving Prednisone[NCT00294658] | Phase 3 | 126 participants (Actual) | Interventional | 2006-06-30 | Completed | ||
| Efficiency and Safety Study of Short-term Prednisone to Treat Moderate and Severe Subacute Thyroiditis[NCT01837433] | Phase 4 | 40 participants (Actual) | Interventional | 2013-03-31 | Completed | ||
| Evaluation of Efficacy and Hypothalamus-pituitary-adrenal Axis Suppression Due to a Single Intrabursal Injection of Corticosteroids in Patients With Shoulder Calcific Tendinopathy[NCT01652495] | Phase 4 | 44 participants (Actual) | Interventional | 2012-03-31 | Completed | ||
| Hydroxychloroquine Exposure in Systemic Lupus Erythematosus (SLE)[NCT03802188] | 3,700 participants (Anticipated) | Observational | 2018-05-09 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
(NCT00294658)
Timeframe: baseline to 3 years
| Intervention | participants (Number) |
|---|---|
| Thymectomy Plus Prednisone | 11 |
| Prednisone Alone | 28 |
Number of patients with MG exacerbation: Thymectomy plus prednisone=6 (out of 66); Prednisone alone=17 (out of 60) (NCT00294658)
Timeframe: baseline to 2 years
| Intervention | days (Mean) |
|---|---|
| Thymectomy Plus Prednisone | 5.5 |
| Prednisone Alone | 26.4 |
Number of patients with MG exacerbation: Thymectomy plus prednisone=6 (out of 66); Prednisone alone=22 (out of 60) (NCT00294658)
Timeframe: baseline to 3 years
| Intervention | days (Mean) |
|---|---|
| Thymectomy Plus Prednisone | 8.7 |
| Prednisone Alone | 22.5 |
Number who had hospitalization: Thymectomy plus prednisone n=15 (out of 66); Prednisone alone n=31 (out of 60) (NCT00294658)
Timeframe: baseline to 3 years
| Intervention | days (Mean) |
|---|---|
| Thymectomy Plus Prednisone | 8.4 |
| Prednisone Alone | 19.2 |
(NCT00294658)
Timeframe: baseline to 3 years
| Intervention | participants (Number) |
|---|---|
| Thymectomy Plus Prednisone | 11 |
| Prednisone Alone | 23 |
Number of participant who experienced at least one serious adverse events over 3 years: Thymectomy plus prednisone n=25 (out of 66); Prednisone alone n=33 (out of 60) (NCT00294658)
Timeframe: baseline to 3 years
| Intervention | participants (Number) |
|---|---|
| Thymectomy Plus Prednisone | 25 |
| Prednisone Alone | 33 |
Number of participant who experienced at least one serious adverse events over 3 years: Thymectomy plus prednisone n=25 (out of 66); Prednisone alone n=33 (out of 60) (NCT00294658)
Timeframe: baseline to 3 years
| Intervention | events (Number) |
|---|---|
| Thymectomy Plus Prednisone | 48 |
| Prednisone Alone | 93 |
For each participant who took azathioprine, we penalized them by taking the maximum dose of prednisone before azathioprine was added. We then applied the same method to compute the time-weighted alternative day prednisone dose from baseline, month 3, 4, 6 and every 3 months through 36 months. (NCT00294658)
Timeframe: baseline, month 3, 4, 6 and every 3 months through 36 months
| Intervention | mg (Mean) |
|---|---|
| Thymectomy Plus Prednisone | 34.4 |
| Prednisone Alone | 64.4 |
For each participant who took azathioprine, we penalized them by taking the prednisone dose at the time azathioprine commenced. We then applied the same method to compute the time-weighted alternative day prednisone dose from baseline, month 3, 4, 6 and every 3 months through 36 months. (NCT00294658)
Timeframe: baseline, month 1 , 2 , 3, 4, 6 and every 3 months through 36 months
| Intervention | mg (Mean) |
|---|---|
| Thymectomy Plus Prednisone | 33.3 |
| Prednisone Alone | 57.9 |
(NCT00294658)
Timeframe: baseline to 3 years
| Intervention | participants (Number) |
|---|---|
| Thymectomy Plus Prednisone | 10 |
| Prednisone Alone | 9 |
Participants reported alternate-day prednisone dose (mg) intake from baseline through withdrawn or completed 3 years follow up. The prednisone dosages had been weighted over the days of reporting period. (NCT00294658)
Timeframe: baseline, month 1 , 2 , 3, 4, 6 and every 3 months through 36 months
| Intervention | mg (Mean) |
|---|---|
| Thymectomy Plus Prednisone | 32 |
| Prednisone Alone | 54 |
MG Activity of Daily Living total scores range from 0 to 24, with the lower scores indicating better daily living quality of life. (NCT00294658)
Timeframe: baseline, month 4, 6 and every 3 months through 36 months
| Intervention | units on a scale (Mean) |
|---|---|
| Thymectomy Plus Prednisone | 2.24 |
| Prednisone Alone | 3.41 |
Physicians reported prescribed alternate-day prednisone dose (mg) intake from baseline through withdrawn or completed 3 years follow up. The prescribed prednisone dosages had been weighted over the days of reporting period. (NCT00294658)
Timeframe: baseline-day 20, month 1,2, 3, 4, 6 and every 3 months through 36 months
| Intervention | mg (Mean) |
|---|---|
| Thymectomy Plus Prednisone | 34.3 |
| Prednisone Alone | 55.6 |
Myasthenia Gravis (QMG) test. QMG total scores range from 0 to 39 for a given visit, with higher scores indicating more severe disease. The time weighted average is a calculation that provides an integrated measure of the outcome over the time of followup. The denominator that was used to compute the time-weighted average for the Quantitative Myasthenia Gravis (QMG) score and the prednisone dose was the number of days from randomization to the last visit. Computations used the trapezoidal method where in the QMG score is multiplied by the number of days at this level from one visit to the next and added up over the entire followup experience and divided by the total number of days from randomization. (NCT00294658)
Timeframe: baseline, month 3, 4, 6 and every 3 months through 36 months
| Intervention | units on a scale (Mean) |
|---|---|
| Thymectomy Plus Prednisone | 6.15 |
| Prednisone Alone | 8.99 |
(NCT00294658)
Timeframe: baseline to 3 years
| Intervention | participants (Number) | |||||
|---|---|---|---|---|---|---|
| Life-threatening | Disability or incapacity | Medical or surgical intervention | Death | Complication due to thytmectomy | Hospitalization | |
| Prednisone Alone | 7 | 2 | 5 | 1 | 0 | 31 |
| Thymectomy Plus Prednisone | 1 | 8 | 9 | 0 | 1 | 15 |
(NCT00294658)
Timeframe: baseline to 2 years and baseline to 3 years
| Intervention | participants (Number) | |
|---|---|---|
| Months 0-24 | Months 0-36 | |
| Prednisone Alone | 17 | 22 |
| Thymectomy Plus Prednisone | 6 | 6 |
Number of participants who were in minimal manifestation status at month 12, 24 and 36. (NCT00294658)
Timeframe: Month 12, 24 and 36
| Intervention | participants (Number) | ||
|---|---|---|---|
| Month 12 | Month 24 | Month 36 | |
| Prednisone Alone | 20 | 20 | 24 |
| Thymectomy Plus Prednisone | 41 | 39 | 39 |
Number who had hospitalization: Thymectomy plus prednisone n=15 (out of 66); Prednisone alone n=31 (out of 60) (NCT00294658)
Timeframe: baseline to 3 years
| Intervention | events (Number) | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Gastrointestinal disorder | Hepatobiliary disorder | Infection or infestation | Injury, poisoning, or procedure complication | Metabolism or nutrition disorder | Nervous system disorder | Respiratory, thoracic, or mediastinal disorder | Surgical or medical procedure | Vascular disorder | |
| Prednisone Alone | 2 | 1 | 7 | 0 | 0 | 22 | 2 | 7 | 1 |
| Thymectomy Plus Prednisone | 2 | 0 | 4 | 2 | 1 | 8 | 1 | 0 | 0 |
Range from 0 to 100, the higher the mental component value, the better the mental health. (NCT00294658)
Timeframe: Month 0, Month 12, Month 24 and Month 36
| Intervention | units on a scale (Median) | |||
|---|---|---|---|---|
| Month 0 | Month 12 | Month 24 | Month 36 | |
| Prednisone Alone | 46.2 | 41.7 | 46.7 | 48.2 |
| Thymectomy Plus Prednisone | 49.1 | 39.1 | 49.9 | 51.7 |
Range from 0 to 100, the higher the physical component value, the better the mental health. (NCT00294658)
Timeframe: Month 0, Month 12, Month 24 and Month 36
| Intervention | units on a scale (Median) | |||
|---|---|---|---|---|
| Month 0 | Month 12 | Month 24 | Month 36 | |
| Prednisone Alone | 37.9 | 44.4 | 43.0 | 44.2 |
| Thymectomy Plus Prednisone | 41.4 | 48.4 | 50.3 | 48.2 |
Participants reported alternate-day prednisone dose (mg) intake from baseline through withdrawn or completed 3 years follow up. The prednisone dosages had been weighted over the days of reporting period. (NCT00294658)
Timeframe: baseline, month 3, 4, 6 and every 3 months through 36 months
| Intervention | mg (Mean) | |
|---|---|---|
| Not prednisone naïve | Prednisone naïve | |
| Prednisone Alone | 56 | 45 |
| Thymectomy Plus Prednisone | 35 | 25 |
Participants reported alternate-day prednisone dose (mg) intake from baseline through withdrawn or completed 3 years follow up. The prednisone dosages had been weighted over the days of reporting period. (NCT00294658)
Timeframe: baseline, month 3, 4, 6 and every 3 months through 36 months
| Intervention | mg (Mean) | |
|---|---|---|
| Female | Male | |
| Prednisone Alone | 54 | 55 |
| Thymectomy Plus Prednisone | 33 | 31 |
Participants reported alternate-day prednisone dose (mg) intake from baseline through withdrawn or completed 3 years follow up. The prednisone dosages had been weighted over the days of reporting period. (NCT00294658)
Timeframe: baseline, month 3, 4, 6 and every 3 months through 36 months
| Intervention | mg (Mean) | |
|---|---|---|
| Age (Years) at Disease Onset < 40 | Age (Years) at Disease Onset ≥ 40 | |
| Prednisone Alone | 55 | 49 |
| Thymectomy Plus Prednisone | 35 | 27 |
Myasthenia Gravis (QMG) test. QMG total scores range from 0 to 39 for a given visit, with higher scores indicating more severe disease. (NCT00294658)
Timeframe: baseline, month 3, 4, 6 and every 3 months through 36 months
| Intervention | units on a scale (Mean) | |
|---|---|---|
| Age (years) at Disease Onset < 40 | Age (years) at Disease Onset ≥ 40 | |
| Prednisone Alone | 9.60 | 7.85 |
| Thymectomy Plus Prednisone | 6.50 | 5.33 |
Myasthenia Gravis (QMG) test. QMG total scores range from 0 to 39 for a given visit, with higher scores indicating more severe disease. (NCT00294658)
Timeframe: baseline, month 3, 4, 6 and every 3 months through 36 months
| Intervention | units on a scale (Mean) | |
|---|---|---|
| Not prednisone naïve | Prednisone naïve | |
| Prednisone Alone | 9.10 | 8.84 |
| Thymectomy Plus Prednisone | 6.30 | 5.66 |
Myasthenia Gravis (QMG) test. QMG total scores range from 0 to 39 for a given visit, with higher scores indicating more severe disease. (NCT00294658)
Timeframe: baseline, month 3, 4, 6 and every 3 months through 36 months
| Intervention | units on a scale (Mean) | |
|---|---|---|
| Female | Male | |
| Prednisone Alone | 9.73 | 7.45 |
| Thymectomy Plus Prednisone | 6.47 | 5.23 |
MG Activity of Daily Living total scores range from 0 to 24 by visit, with the lower scores indicating better daily living quality of life. (NCT00294658)
Timeframe: Month 12, 24, and 36
| Intervention | units on a scale (Mean) | ||
|---|---|---|---|
| Month 12 | Month 24 | Month 36 | |
| Prednisone Alone | 3.33 | 3.11 | 2.69 |
| Thymectomy Plus Prednisone | 1.92 | 2.02 | 2.14 |
Treatment associated complications measured complications occurred by myasthenia gravis patients. Report number of participant with at least one complications by each visit. (NCT00294658)
Timeframe: Month 0, 1, 2, 3, 4 then every 3 months through Month 36
| Intervention | Participants (Count of Participants) | |||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Month 0 | Month 1 | Month 2 | Month 3 | Month 4 | Month 6 | Month 9 | Month 12 | Month 15 | Month 18 | Month 21 | Mpnth 24 | Mpnth 27 | Month 30 | Month 33 | Month 36 | |
| Prednisone Alone | 17 | 15 | 20 | 16 | 23 | 22 | 26 | 28 | 24 | 24 | 20 | 23 | 17 | 19 | 23 | 23 |
| Thymectomy Plus Prednisone | 22 | 15 | 22 | 21 | 23 | 21 | 37 | 35 | 29 | 28 | 22 | 28 | 25 | 23 | 24 | 23 |
Treatment associated symptoms measured myasthenia gravis symptoms such as back pain and/or bruises. Report number of participant with at least one treatment associated symptoms by each visit. (NCT00294658)
Timeframe: Month 0, 1, 2, 3, 4 then every 3 months through Month 36
| Intervention | Participants (Count of Participants) | |||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Month 0 | Month 1 | Month 2 | Month 3 | Month 4 | Month 6 | Month 9 | Month 12 | Month 15 | Month 18 | Month 21 | Mpnth 24 | Mpnth 27 | Month 30 | Month 33 | Month 36 | |
| Prednisone Alone | 53 | 52 | 53 | 54 | 54 | 53 | 50 | 52 | 51 | 51 | 50 | 51 | 50 | 50 | 48 | 47 |
| Thymectomy Plus Prednisone | 63 | 55 | 61 | 60 | 59 | 60 | 59 | 56 | 56 | 52 | 52 | 52 | 50 | 49 | 51 | 49 |
"Patients will be evaluated clinically by Constant Score~Constant score: range 0 (total shoulder impairment) to 100 (non impaired shoulder). The score is obtained from two subjective (pain and relation between pain and daily-life activities) - and two objective physician-assessed (strength and range of motion) measurements~Reference: Constant CR and Murley AH. A clinical method of functional assessment of the shoulder. Clin Orthop Relat Res. 1987 Jan;(214):160-4." (NCT01652495)
Timeframe: 180 days after treatment
| Intervention | percentage of improvement Constant score (Mean) |
|---|---|
| Methylprednisolone Acetate Group | 99 |
| Triamcinolone Acetonide Group | 95 |
"Evaluation of blood cortisol and ACTH, free urinary cortisol, urinary levels of methylprednisolone or triamcinolone (depending on the administered drug) by RIA immunoassay and tandem mass assays~Persistent suppression of the HPA axis at the end of the follow up is based on the evidence of ACTH, plasmatic and urinary cortisol levels under reference values" (NCT01652495)
Timeframe: 45 days after treatment
| Intervention | % of patients with HPA suppression (Number) |
|---|---|
| Methylprednisolone Acetate Group | 0 |
| Triamcinolone Acetonide Group | 15 |
"VAS score~VAS score is a 10 -cm graduated scale with scores ranging from 0 (no pain) to 10 (unbearable pain) self- reported by patients~Reference: Langley GB and Sheppeard H. The visual analogue scale: its use in pain measurement. Rheumatol Int 1985;5(4):145-148." (NCT01652495)
Timeframe: 180 days after treatment
| Intervention | percentage of pain reduction (Mean) |
|---|---|
| Methylprednisolone Acetate Group | 82 |
| Triamcinolone Acetonide Group | 96 |
7 reviews available for prednisone and Drug Withdrawal Symptoms
| Article | Year |
|---|---|
Sustained corticosteroid- induced mania and psychosis despite cessation: A case study and brief literature review.
Topics: Adrenal Cortex Hormones; Bipolar Disorder; Dexamethasone; Dose-Response Relationship, Drug; Drug Adm | 2015 |
Minimization of steroids in kidney transplantation.
Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Child; Clinical Trials as Topic; Daclizum | 2009 |
Optimizing the use of docetaxel in men with castration-resistant metastatic prostate cancer.
Topics: Androgen Antagonists; Antineoplastic Agents; Clinical Trials as Topic; Docetaxel; Drug Administratio | 2010 |
Drug-induced vasculitis: a clinical and pathological review.
Topics: Antibodies, Antineutrophil Cytoplasmic; Diagnosis, Differential; Disease Progression; Drug Hypersens | 2012 |
Chemical dependence involving glucocorticoids.
Topics: Behavior, Addictive; Depression; Glucocorticoids; Humans; Male; Middle Aged; Prednisone; Self Medica | 1997 |
Use and abuse of systemic corticosteroid therapy.
Topics: Adrenal Cortex Hormones; Dermatitis; Drug Administration Schedule; Humans; Hypothalamo-Hypophyseal S | 1979 |
Corticosteroid therapy for rheumatoid arthritis.
Topics: Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Arthritis, Rheumatoid; Atrophy; Betamethasone; | 1973 |
17 trials available for prednisone and Drug Withdrawal Symptoms
| Article | Year |
|---|---|
Minimal manifestation status and prednisone withdrawal in the MGTX trial.
Topics: Adolescent; Adult; Animals; Combined Modality Therapy; Female; Humans; Immunosuppressive Agents; Mal | 2020 |
[Clinical observation on effect of yiqi yangyin principle on corticosteroid withdrawal in patients with systemic lupus erythematosus at remission stage].
Topics: Adolescent; Adult; Child; Complement C3; Drugs, Chinese Herbal; Female; Humans; Immunoglobulin G; Lu | 2002 |
Out-patient detoxification in chronic migraine: comparison of strategies.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Ambulatory Care; Chi-Square Distribution; Female; Headac | 2003 |
Steroid withdrawal syndrome during steroid tapering in childhood acute lymphoblastic leukemia: a controlled study comparing prednisone versus dexamethasone in induction phase.
Topics: Adolescent; Antineoplastic Agents, Hormonal; Child; Child, Preschool; Dexamethasone; Female; Glucoco | 2005 |
Adrenal axis function after high-dose steroid therapy for childhood acute lymphoblastic leukemia.
Topics: Adrenal Cortex; Adrenal Insufficiency; Adrenocorticotropic Hormone; Antineoplastic Combined Chemothe | 2008 |
Prednisone vs. placebo in withdrawal therapy following medication overuse headache.
Topics: Adult; Double-Blind Method; Female; Glucocorticoids; Headache Disorders, Secondary; Humans; Male; Mi | 2008 |
Risk of steroid withdrawal in pediatric renal allograft recipients (a 5-year follow-up).
Topics: Acute Disease; Adolescent; Child; Female; Follow-Up Studies; Graft Rejection; Humans; Immunosuppress | 1994 |
In vitro sensitivity to prednisolone may predict kidney rejection after steroid withdrawal.
Topics: Adult; Cyclosporine; Drug Hypersensitivity; Female; Graft Rejection; Humans; Kidney Transplantation; | 1996 |
Long-term outcome of a prospective trial of steroid withdrawal after kidney transplantation.
Topics: Acute Disease; Adult; Aged; Anti-Inflammatory Agents; Chronic Disease; Diabetes Mellitus; Female; Gl | 1999 |
[Assessment on application of Chinese herbs in process of corticosterone reduction in nephrotic syndrome].
Topics: Adolescent; Adult; Anti-Inflammatory Agents; Drugs, Chinese Herbal; Humans; Male; Middle Aged; Nephr | 2000 |
Beclomethasone in steroid-dependent asthma. Effective therapy and recovery of hypothalamo-pituitary-adrenal function.
Topics: Administration, Oral; Adrenal Glands; Aerosols; Asthma; Beclomethasone; Chronic Disease; Clinical Tr | 1977 |
A controlled trial of inhaled corticosteroids in patients receiving Prednisone tablets for asthma.
Topics: Aerosols; Asthma; Beclomethasone; Betamethasone; Betamethasone Valerate; Clinical Trials as Topic; F | 1976 |
A pilot study of steroid withdrawal followed by oral acyclovir in the treatment of chronic type B hepatitis.
Topics: Acyclovir; Administration, Oral; Adolescent; Adult; Alanine Transaminase; Chemical and Drug Induced | 1992 |
Safety and efficacy of interferon alpha-2b following prednisone withdrawal in the treatment of chronic viral hepatitis B. A case-controlled, randomised study.
Topics: Adolescent; Adult; Aged; Female; Hepatitis B; Hepatitis, Chronic; Humans; Interferon alpha-2; Interf | 1992 |
A randomized study of the effect of withdrawing hydroxychloroquine sulfate in systemic lupus erythematosus.
Topics: Adult; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hydroxychloroquine; Lupus Ery | 1991 |
Cardiac allograft function with corticosteroid-free maintenance immunosuppression.
Topics: Antibodies, Monoclonal; Antilymphocyte Serum; Female; Follow-Up Studies; Graft Rejection; Heart Tran | 1990 |
Beclomethasone dipropionate aerosol in asthma. Transfer of steroid-dependent asthmatic patients from oral prednisone to beclomethasone dipropionate aerosol.
Topics: Administration, Oral; Administration, Topical; Adrenal Insufficiency; Aerosols; Anti-Inflammatory Ag | 1974 |
63 other studies available for prednisone and Drug Withdrawal Symptoms
| Article | Year |
|---|---|
Long-term abiraterone withdrawal syndrome.
Topics: Abiraterone Acetate; Antineoplastic Combined Chemotherapy Protocols; Docetaxel; Humans; Male; Predni | 2018 |
Prednisone in withdrawal therapy following medication overuse headache.
Topics: Adolescent; Anti-Inflammatory Agents; Child; Contraindications; Headache Disorders, Secondary; Human | 2008 |
Dexamethasone suppression test predicts later development of an impaired adrenal function after a 14-day course of prednisone in healthy volunteers.
Topics: Adrenal Insufficiency; Adrenocorticotropic Hormone; Adult; Dexamethasone; Humans; Hydrocortisone; Hy | 2010 |
Influence of African-American ethnicity on acute rejection after early steroid withdrawal in primary kidney transplant recipients.
Topics: Adrenal Cortex Hormones; Adult; Aged; Black or African American; Drug Administration Schedule; Drug | 2010 |
Mortality from cerebral vasculitis associated with rapid steroid taper during treatment of acute posterior multifocal placoid pigment epitheliopathy.
Topics: Administration, Oral; Fatal Outcome; Female; Fluorescein Angiography; Glucocorticoids; Humans; Middl | 2012 |
Glucocorticoid withdrawal - heterozygous carriers of congenital adrenal hyperplasia at risk?
Topics: Adrenal Hyperplasia, Congenital; Adrenocorticotropic Hormone; Adrenogenital Syndrome; Antineoplastic | 2012 |
Histological features associated with relapse after corticosteroid withdrawal in type 1 autoimmune hepatitis.
Topics: Adrenal Cortex Hormones; Adult; Azathioprine; Biopsy; Female; Follow-Up Studies; Hepatitis, Autoimmu | 2003 |
Acute adrenal crisis in a patient treated with rectal steroids.
Topics: Acute Disease; Adrenal Gland Diseases; Adult; Anti-Inflammatory Agents; Colitis, Ulcerative; Enema; | 2004 |
Relieving rebound headaches.
Topics: Analgesics; Anti-Inflammatory Agents; Emergency Nursing; Headache; Humans; Nonprescription Drugs; Nu | 2007 |
Steroid-withdrawal radiation pneumonitis in cancer patients.
Topics: Adenocarcinoma; Aged; Breast Neoplasms; Carcinoma, Small Cell; Combined Modality Therapy; Dexamethas | 1984 |
Steroid-dependent nephrotic syndrome in lupus nephritis. Response to chlorambucil.
Topics: Adult; Chlorambucil; Female; Glomerulonephritis; Humans; Lupus Erythematosus, Systemic; Nephrotic Sy | 1984 |
Fever on drug-free day of alternate-day steroid therapy.
Topics: Aged; Drug Administration Schedule; Female; Fever; Humans; Prednisone; Substance Withdrawal Syndrome | 1984 |
Long-term triamcinolone acetonide aerosol treatment in adult patients with chronic bronchial asthma.
Topics: Adolescent; Adult; Aerosols; Aged; Asthma; Auscultation; Blood; Dose-Response Relationship, Drug; El | 1980 |
Withdrawal of azathioprine after renal transplantation.
Topics: Azathioprine; Creatinine; Humans; Immunoglobulin Idiotypes; Kidney Transplantation; Liver Diseases; | 1980 |
Steroid withdrawal following HLA-identical related donor transplantation.
Topics: Adolescent; Adult; Diabetes Mellitus; Female; Graft Survival; Histocompatibility Testing; HLA Antige | 1981 |
On the various forms of corticosteroid withdrawal syndrome.
Topics: Adrenal Cortex Hormones; Adult; Cortisone; Depression, Chemical; Female; Humans; Hydrocortisone; Hyp | 1980 |
Tuberculous peritonitis complicating corticosteroid therapy for acute alcoholic hepatitis.
Topics: Acute Disease; Adult; Female; Glucocorticoids; Hepatitis, Alcoholic; Humans; Peritonitis, Tuberculou | 1995 |
[Investigation of treating steroids dependent asthmatic patients with kidney-tonifying herbs and high dose beclomethasone dipropionate aerosol].
Topics: Aerosols; Asthma; Beclomethasone; Drugs, Chinese Herbal; Female; Humans; Male; Prednisone; Respirato | 1994 |
Elective cyclosporine withdrawal 1 year after renal transplantation.
Topics: Acute Disease; Adult; Azathioprine; Cyclosporine; Drug Administration Schedule; Female; Graft Reject | 1994 |
[Potential risks of the withdrawal of corticoids in Horton's disease. Prospective study of 22 patients].
Topics: Adrenal Insufficiency; Aged; Giant Cell Arteritis; Humans; Hydrocortisone; Prednisone; Prospective S | 1993 |
Pseudotumor cerebri associated with corticosteroid withdrawal in inflammatory bowel disease.
Topics: Adolescent; Adult; Colitis, Ulcerative; Crohn Disease; Female; Fundus Oculi; Headache; Humans; Male; | 1994 |
Cyclosporine withdrawal for nephrotoxicity in liver transplant recipients does not result in sustained improvement in kidney function and causes cellular and ductopenic rejection.
Topics: Azathioprine; Creatinine; Cyclosporine; Drug Therapy, Combination; Female; Follow-Up Studies; Graft | 1994 |
[134 patients with adult primary nephrotic syndrome treated with combined traditional Chinese medicine and Western medicine].
Topics: Adolescent; Adult; Cushing Syndrome; Drug Therapy, Combination; Drugs, Chinese Herbal; Female; Human | 1993 |
Unstable angina in a man with joint pain.
Topics: Angina, Unstable; Arthritis, Rheumatoid; Coronary Disease; Diagnosis, Differential; Edema; Humans; M | 1993 |
The beneficial effects of steroid withdrawal on blood pressure and lipid profile in children posttransplantation in the cyclosporine era.
Topics: Adolescent; Blood Pressure; Child; Child, Preschool; Cholesterol; Cholesterol, LDL; Cyclosporine; Fe | 1993 |
Determinants of long-term allograft function following steroid withdrawal in renal transplant recipients.
Topics: Adult; Aged; Azathioprine; Cyclosporine; Dose-Response Relationship, Drug; Female; Follow-Up Studies | 1995 |
[Fever as expression of corticoid withdrawal syndrome in chronic obstructive pulmonary disease].
Topics: Adrenal Cortex Hormones; Aged; Aged, 80 and over; Anti-Inflammatory Agents; Fever; Humans; Lung Dise | 1996 |
[Pseudotumorous presentation of neuro-Behçet: role of the withdrawal of colchicine?].
Topics: Anti-Inflammatory Agents; Behcet Syndrome; Brain Diseases; Colchicine; Cyclophosphamide; Female; Fol | 1998 |
Churg-Strauss syndrome and antiasthma therapy.
Topics: Asthma; Churg-Strauss Syndrome; Female; Glucocorticoids; Humans; Middle Aged; Prednisone; Substance | 1999 |
Glucocorticoid-induced adrenal insufficiency.
Topics: Adrenal Insufficiency; Adult; Anti-Inflammatory Agents; Asthma; Diagnosis, Differential; Female; Glu | 1999 |
Glucocorticoid-induced adrenal insufficiency.
Topics: Adrenal Insufficiency; Adult; Anti-Inflammatory Agents; Asthma; Diagnosis, Differential; Female; Glu | 1999 |
Glucocorticoid-induced adrenal insufficiency.
Topics: Adrenal Insufficiency; Adult; Anti-Inflammatory Agents; Asthma; Diagnosis, Differential; Female; Glu | 1999 |
Glucocorticoid-induced adrenal insufficiency.
Topics: Adrenal Insufficiency; Adult; Anti-Inflammatory Agents; Asthma; Diagnosis, Differential; Female; Glu | 1999 |
Seven cases of complete and incomplete forms of Churg-Strauss syndrome not related to leukotriene receptor antagonists.
Topics: Adult; Aged; Anti-Inflammatory Agents; Asthma; Churg-Strauss Syndrome; Female; Glucocorticoids; Huma | 1999 |
Prednisone as initial treatment of analgesic-induced daily headache.
Topics: Adult; Analgesics; Anti-Inflammatory Agents; Emotions; Female; Headache; Humans; Male; Middle Aged; | 2000 |
Shen's experience in application of the drugs for tonifying the kidney to reduce and withdraw adrenocortical hormone.
Topics: Adolescent; Adult; Anti-Inflammatory Agents; Asthma; Drugs, Chinese Herbal; Female; Humans; Male; Mi | 2001 |
Steroid-induced psychosis treated with risperidone.
Topics: Adult; Antipsychotic Agents; Asthma; Drug Therapy, Combination; Female; Humans; Hydrocortisone; Pred | 2002 |
Defining the risk of elective cyclosporine withdrawal in stable kidney transplant recipients.
Topics: Antilymphocyte Serum; Confidence Intervals; Cyclosporine; Dose-Response Relationship, Drug; Follow-U | 2002 |
Aerosol beclomethasone treatment of chronic severe asthma. A one-year experience.
Topics: Administration, Oral; Aerosols; Asthma; Beclomethasone; Humans; Nasal Polyps; Pharyngitis; Prednison | 1978 |
Pericardial tamponade secondary to sudden steroid withdrawal in chronic rheumatoid arthritis.
Topics: Arthritis, Rheumatoid; Cardiac Tamponade; Cervical Vertebrae; Chronic Disease; Female; Fractures, Bo | 1977 |
Evaluation of a new aerosolized steroid for asthma therapy: beclomethasone dipropionate (Vanceril inhaler).
Topics: Administration, Oral; Adult; Aerosols; Asthma; Beclomethasone; Child; Drug Administration Schedule; | 1976 |
[Heparin-induced thrombosis-thrombocytopenia syndrome in Crohn disease. Further thromboses with oral anticoagulation after discontinuation of heparin].
Topics: Administration, Oral; Blood Coagulation Tests; Crohn Disease; Drug Therapy, Combination; Female; Hep | 1992 |
The effects of steroid withdrawal on the lipoprotein profiles of cyclosporine-treated kidney and kidney-pancreas transplant recipients.
Topics: Adult; Apolipoprotein A-I; Apolipoproteins B; Cholesterol, HDL; Cholesterol, LDL; Cyclosporine; Fema | 1992 |
Adrenocortical suppression presenting with agitated depression, morbid jealousy, and a dementia-like state.
Topics: Aged; Akathisia, Drug-Induced; Asthma; Dementia; Depressive Disorder; Female; Humans; Jealousy; Neur | 1991 |
Follow-up of cyclosporine-treated pediatric renal allograft recipients after cessation of prednisone.
Topics: Adolescent; Child; Child, Preschool; Cholesterol; Cyclosporins; Female; Follow-Up Studies; Graft Rej | 1990 |
Appearance of Guillain-Barré syndrome in patients during corticosteroid treatment.
Topics: Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Aged; Colitis, Ulcerative; Dexamethasone; Fema | 1986 |
Secondary mania with steroid withdrawal.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Bipolar Disorder; Dose-Response Relationship, | 1988 |
Withdrawal of steroid immunosuppression in renal transplant recipients.
Topics: Adult; Azathioprine; Cyclosporins; Female; Graft Rejection; Haplotypes; Histocompatibility Testing; | 1988 |
Onset of type I diabetes mellitus, hypothyroidism, and hypogonadism on withdrawal of glucocorticoid therapy and remission on its resumption in a patient with rheumatoid arthritis.
Topics: Arthritis, Rheumatoid; Autoimmune Diseases; Diabetes Mellitus, Type 1; Humans; Hypogonadism; Hypothy | 1986 |
Cortisone withdrawal rebound phenomena and histamine.
Topics: Asthma; Histamine; Histamine Release; Humans; Ileum; Muscle Contraction; Prednisone; Substance Withd | 1971 |
Letter: Acute arthralgia following high-dose intravenous methylprednisolone therapy.
Topics: Acute Disease; Administration, Oral; Adult; Female; Graft Rejection; Humans; Injections, Intravenous | 1974 |
[Clinical syndrome of the iatrogenic hypercorticoidism].
Topics: Adolescent; Adult; Aged; Collagen Diseases; Drug Eruptions; Drug Hypersensitivity; Female; Glucocort | 1969 |
Certain endocrine and metabolic facets of the steroid withdrawal syndrome.
Topics: 17-Hydroxycorticosteroids; Adrenocorticotropic Hormone; Blood; Cushing Syndrome; Humans; Hypothalamo | 1965 |
Abrupt withdrawal of adrenal corticosteroids in patients with rheumatoid arthritis: the clinical observations of twelve cases.
Topics: Adrenal Insufficiency; Adrenocorticotropic Hormone; Adult; Aged; Arthritis, Rheumatoid; Female; Huma | 1967 |
Systemic corticosteroids in dermatology.
Topics: Adrenocorticotropic Hormone; Humans; Prednisone; Skin Diseases; Substance Withdrawal Syndrome | 1968 |
Plasma cortisol monitoring and use of ACTH in asthma.
Topics: Adolescent; Adrenal Glands; Adrenocorticotropic Hormone; Adult; Asthma; Child; Female; Humans; Hydro | 1969 |
Using corticosteroids.
Topics: Adrenal Cortex Hormones; Adrenal Glands; Adrenocorticotropic Hormone; Drug Synergism; Glucocorticoid | 1971 |
Corticosteroid withdrawal in asthma.
Topics: Adrenal Gland Diseases; Adrenocorticotropic Hormone; Adult; Asthma; Beclomethasone; Female; Humans; | 1973 |
Recovery of adrenal function after substitution of beclomethasone dipropionate for oral corticosteroids.
Topics: Administration, Oral; Administration, Topical; Adrenal Insufficiency; Adrenocorticotropic Hormone; A | 1973 |
Addiction to prednisone.
Topics: Adult; Anxiety; Anxiety Disorders; Asthma; Cushing Syndrome; Female; Humans; Prednisone; Substance W | 1973 |
The effect of glucocorticoid withdrawal on body water and electrolytes in hypopituitary patients with adrenocortical insufficiency as investigated with 77 Br, 43 K, 24 Na and 3 H 2 O.
Topics: Adrenal Insufficiency; Body Fluids; Body Water; Bromine; Cortisone; Desoxycorticosterone; Extracellu | 1972 |
Psychological dependency on steroids?
Topics: Anxiety; Arthritis, Rheumatoid; Asthma; Brain; Depression; Female; Glucocorticoids; Humans; Middle A | 1971 |
Steroid "pseudorheumatism" in asthma.
Topics: Adult; Asthma; Female; Humans; Male; Middle Aged; Prednisone; Rheumatic Diseases; Substance Withdraw | 1969 |
Systemic fat embolism after renal homotransplantation and treatment with corticosteroids.
Topics: Adult; Embolism, Fat; Fatty Liver; Female; Humans; Immunosuppressive Agents; Kidney Transplantation; | 1965 |
[On the cortisone withdrawal syndrome].
Topics: Adrenal Insufficiency; Aged; Arthritis, Rheumatoid; Female; Fluprednisolone; Glucocorticoids; Humans | 1967 |
Children with asthma.
Topics: Adrenal Cortex Hormones; Asthma; Child; Humans; Prednisone; Substance Withdrawal Syndrome | 1968 |