Compounds > prednisone
Page last updated: 2024-11-07

prednisone and Drug-Induced Stevens Johnson Syndrome

prednisone has been researched along with Drug-Induced Stevens Johnson Syndrome in 54 studies

Prednisone: A synthetic anti-inflammatory glucocorticoid derived from CORTISONE. It is biologically inert and converted to PREDNISOLONE in the liver.
prednisone : A synthetic glucocorticoid drug that is particularly effective as an immunosuppressant, and affects virtually all of the immune system. Prednisone is a prodrug that is converted by the liver into prednisolone (a beta-hydroxy group instead of the oxo group at position 11), which is the active drug and also a steroid.

Research Excerpts

ExcerptRelevanceReference
"EMBASE (1974 to April 2014), MEDLINE (1946 to April 2014), Cochrane Database of Systematic Reviews, and International Pharmaceutical Abstracts (1970 to January 2014) were searched using the terms: prednisone, methylprednisolone, dexamethasone, prednisolone, steroids, glucocorticoids, corticosteroids, Stevens-Johnson Syndrome, toxic epidermal necrolysis, and SJS/TEN overlap."4.91Corticosteroids in Stevens-Johnson Syndrome/toxic epidermal necrolysis: current evidence and implications for future research. ( Law, EH; Leung, M, 2015)
"An 8-year-old boy developed erythema multiforme major after topical administration of sodium sulfacetamide for conjunctivitis."3.67Erythema multiforme after use of topical sulfacetamide. ( Blecher, MH; Cohen, EJ; Donnenfeld, ED; Genvert, GI, 1985)
"Stevens-Johnson syndrome and toxic epidermal necrolysis are life-threatening dermatological conditions."1.42[Systemic lupus erythematosus presenting as Stevens-Johnson syndrome]. ( Bellakhal, S; Ben Kaab, B; Derbel, F; Douggui, MH; Souissi, A; Teyeb, Z, 2015)
"Hodgkin's disease has been associated with a variety of cutaneous symptoms."1.40[Stevens-Johnson syndrome and Hodgkin's disease: A fortuitous association or paraneoplastic syndrome?]. ( Barbaud, A; Bursztejn, AC; Cribier, B; Cuny, JF; Levy, E; Schmutz, JL; Schoeffler, A; Weinborn, M, 2014)
"This survey considers 8 cases of toxic epidermal necrolysis diagnosed and treated in our clinic from 2003 to 2007."1.36Basic measures and systemic medical treatment of patients with toxic epidermal necrolysis. ( Hanken, I; Sander, CA; Schimmer, M, 2010)
"Prednisone therapy was continued until the patient was discharged on hospital day 5, at which time the dosage was tapered."1.29Reversal of erythema multiforme major with cyclophosphamide and prednisone. ( Cole, GW; Eastham, JH; Gómez, MF; Segal, JL, 1996)
"A 35-year-old woman developed toxic epidermal necrolysis secondary to phenytoin."1.28Drug-induced toxic epidermal necrolysis treated with cyclosporin. ( Daman, LA; Grant-Kels, JM; Renfro, L, 1989)
"The diagnosis of drug-related toxic epidermal necrolysis was made on the basis of clinical history and histologic features."1.27Toxic epidermal necrolysis in a patient affected by mixed essential cryoglobulinemia. ( Cottoni, F; Solinas, A; Tanda, F; Tocco, A, 1988)
" It is concluded that allopurinol should be used only in select patients, and the dosage should be modified if renal disease exists."1.26Severe hypersensitivity reactions to allopurinol. ( Lang, PG, 1979)

Research

Studies (54)

TimeframeStudies, this research(%)All Research%
pre-199034 (62.96)18.7374
1990's9 (16.67)18.2507
2000's4 (7.41)29.6817
2010's7 (12.96)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Cafasso, A1
Rao, F1
Mucciarone, L1
Ambrosino Di Miccio, S1
Dumas, M1
Hua, C1
Hotz, C1
Velter, C1
Duong, TA1
Maraffi, T1
Ortonne, N1
Hüe, S1
Fardet, L1
de Prost, N1
Wolkenstein, P1
Ingen-Housz-Oro, S1
Chosidow, O1
Schoeffler, A1
Levy, E1
Weinborn, M1
Cuny, JF1
Schmutz, JL1
Barbaud, A1
Cribier, B1
Bursztejn, AC1
Law, EH1
Leung, M1
Bellakhal, S1
Ben Kaab, B1
Teyeb, Z1
Souissi, A1
Derbel, F1
Douggui, MH1
Ahmed, R1
Eagleton, C1
Hanken, I1
Schimmer, M1
Sander, CA1
Tomlow, B1
Assen, Y1
Konda, S1
Fernandez, AP1
Berman, B1
Elgart, G1
Milikowski, C1
Alonso-Llamazares, J1
RUSSO, N1
DEBETHUNE, G1
VANNOYEN, G1
CASCIO, G1
BUTTITTA, P1
COSTANTINO, E1
MUSGNUG, R1
FLOYD, F1
KAZANSKII, IV1
KIFER, EL1
TIKHONRAVOVA, EK1
FEDCHINA, ZI1
McCann, DJ1
Nadel, ES1
Brown, DF1
Wittig, Ch1
Sanchez, E1
Shirahama, J1
Rüdt, R1
Helm, J1
Mann, G1
Hövels, O1
Caldwell, IW1
Montgomery, PR1
Peachey, RD1
Edmond, BJ1
Huff, JC1
Weston, WL1
Golden, HE2
Larrègue, M1
Pouvreau, A1
Prigent, F1
Lorette, G1
Canuel, C1
Cuthbert, RJ1
Craig, JI1
Ludlam, CA1
Zachariae, H1
Esmann, J1
Eastham, JH1
Segal, JL1
Gómez, MF1
Cole, GW1
Srivastava, M1
Perez-Atayde, A1
Jonas, MM1
Lang, PG1
Haughey, DB1
Lanse, S1
Imhoff, T1
Tobin, M1
Schentag, JJ1
Elias, PM2
Levy, SW1
Rasmussen, JE1
Detjen, PF1
Patterson, R2
Noskin, GA1
Phair, JP1
Loyd, SO1
Edell, DS1
Davidson, JJ1
Muelenaer, AA1
Majure, M1
Roosje, PJ1
Dykewicz, MS1
Gonzalzles, A1
Grammer, LC1
Green, D1
Greenberger, PA1
McGrath, KG1
Walker, CL1
Renfro, L1
Grant-Kels, JM1
Daman, LA1
Genvert, GI1
Cohen, EJ1
Donnenfeld, ED1
Blecher, MH1
Taylor, B1
Duffill, M1
Solinas, A1
Cottoni, F1
Tanda, F1
Tocco, A1
Parsons, JM1
Heng, MC1
Spahr, A1
Rossier, J1
Délèze, G1
Ohlenschlaeger, K1
Tritsch, H1
Orfanos, C1
Lückerath, I1
Adam, JE1
Peck, GL1
Herzig, GP1
Rudolph, RI1
Schwartz, W1
Leyden, JJ1
Krumlovsky, FA1
Del Greco, F1
Herdson, PB1
Lazar, P1
Lalla, M1
Virolainen, M1
Loggie, JM1
Stratigos, JD1
Bartsokas, SK1
Capetanakis, J1
Stiller, I1
Schuppli, R1
Sander, J1
Höfer, W1
Hönemann, W1

Reviews

6 reviews available for prednisone and Drug-Induced Stevens Johnson Syndrome

ArticleYear
Corticosteroids in Stevens-Johnson Syndrome/toxic epidermal necrolysis: current evidence and implications for future research.
    The Annals of pharmacotherapy, 2015, Volume: 49, Issue:3

    Topics: Adrenal Cortex Hormones; Adult; Biomedical Research; Cardiovascular Agents; Cross-Sectional Studies;

2015
Erythema multiforme.
    Pediatric clinics of North America, 1983, Volume: 30, Issue:4

    Topics: Diagnosis, Differential; Drug Hypersensitivity; Erythema; Erythema Multiforme; Herpes Simplex; Human

1983
Erythema multiforme and Stevens-Johnson syndrome. Descriptive and therapeutic controversy.
    Chest, 1990, Volume: 98, Issue:2

    Topics: Erythema Multiforme; Female; Humans; Hydrocortisone; Middle Aged; Prednisone; Stevens-Johnson Syndro

1990
Management of toxic epidermal necrolysis.
    Cutis, 1985, Volume: 36, Issue:4

    Topics: Adult; Child; Female; Humans; Mafenide; Prednisone; Prognosis; Silver Nitrate; Stevens-Johnson Syndr

1985
Exofoliative dermatitis (erythroderma).
    Current problems in dermatology, 1972, Volume: 4

    Topics: Adrenal Cortex Hormones; Adult; Anemia; Blood Proteins; Body Temperature Regulation; Cardiac Output;

1972
Hypertension in children and adolescents. I. Causes and diagnostic studies.
    The Journal of pediatrics, 1969, Volume: 74, Issue:3

    Topics: Adrenal Gland Neoplasms; Blood Pressure; Blood Pressure Determination; Child; Child, Preschool; Fema

1969

Other Studies

48 other studies available for prednisone and Drug-Induced Stevens Johnson Syndrome

ArticleYear
Stevens-Johnson syndrome presumably induced by bromhexine. A case report.
    Minerva stomatologica, 2002, Volume: 51, Issue:4

    Topics: Adult; Anthelmintics; Bromhexine; Expectorants; Humans; Male; Mouth Mucosa; Organic Chemicals; Penis

2002
Epidermal necrolysis and autoimmune diseases: two more observations supporting the concept that 'toxic' epidermal necrolysis can be 'non-toxic'.
    Journal of the European Academy of Dermatology and Venereology : JEADV, 2018, Volume: 32, Issue:9

    Topics: Antibodies, Antinuclear; Autoimmune Diseases; Cyclophosphamide; Fatal Outcome; Female; Humans; Hydro

2018
[Stevens-Johnson syndrome and Hodgkin's disease: A fortuitous association or paraneoplastic syndrome?].
    Annales de dermatologie et de venereologie, 2014, Volume: 141, Issue:2

    Topics: Adrenal Cortex Hormones; Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Causality

2014
[Systemic lupus erythematosus presenting as Stevens-Johnson syndrome].
    Pathologie-biologie, 2015, Volume: 63, Issue:4-5

    Topics: Adult; Anemia; Arthralgia; Autoantibodies; Complement C3; Critical Care; Facial Dermatoses; Female;

2015
Toxic epidermal necrolysis after paroxetine treatment.
    The New Zealand medical journal, 2008, May-23, Volume: 121, Issue:1274

    Topics: Aged, 80 and over; Anti-Inflammatory Agents; Antidepressive Agents, Second-Generation; Biopsy; Depre

2008
Basic measures and systemic medical treatment of patients with toxic epidermal necrolysis.
    Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG, 2010, Volume: 8, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Allopurinol; Anti-Bacterial Agents; Anti-Inflammatory Agents; Antico

2010
[A woman with skin lesions over her whole body].
    Nederlands tijdschrift voor geneeskunde, 2011, Volume: 155

    Topics: Adult; Anti-Inflammatory Agents; Carbamazepine; Female; Humans; Prednisone; Stevens-Johnson Syndrome

2011
Toxic epidermal necrolysis in the setting of systemic lupus erythematosus.
    International journal of dermatology, 2011, Volume: 50, Issue:10

    Topics: Acute Disease; Anemia, Hemolytic; Anti-Inflammatory Agents; Antibodies, Antinuclear; Female; Humans;

2011
[CONSIDERATIONS ON 2 CASES OF STEVENS-JOHNSON SYNDROME].
    La Riforma medica, 1963, Aug-31, Volume: 77

    Topics: Anti-Bacterial Agents; Bronchopneumonia; Humans; Italy; Pathology; Prednisone; Protein Synthesis Inh

1963
[TOXIC EPIDERMAL NECROLYSIS (LYELL'S SYNDROME) IN CHILDREN].
    Acta paediatrica Belgica, 1964, Volume: 18

    Topics: Adrenocorticotropic Hormone; Anti-Bacterial Agents; Child; Chloramphenicol; Drug Eruptions; Humans;

1964
[ON 2 CASES OF EPIDERMAL NECROLYSIS (LYELL'S SYNDROME)].
    Minerva pediatrica, 1964, Feb-25, Volume: 16

    Topics: Analgesics; Analgesics, Non-Narcotic; Anti-Infective Agents, Local; Antipyretics; Child; Cortisone;

1964
TOXIC EPIDERMAL NECROLYSIS. TWO CASES IN CHILDREN WITH A REVIEW OF THE AMERICAN LITERATURE.
    American journal of diseases of children (1960), 1964, Volume: 108

    Topics: Child; Conjunctivitis; Drug Eruptions; Drug Therapy; Hydrocortisone; Infant; Infusions, Parenteral;

1964
[ON THE STEVENS-JOHNSON SYNDROME].
    Voprosy okhrany materinstva i detstva, 1964, Volume: 9

    Topics: Blindness; Child; Humans; Pathology; Prednisone; Sepsis; Stevens-Johnson Syndrome

1964
Rash and fever.
    The Journal of emergency medicine, 2006, Volume: 31, Issue:3

    Topics: Adult; Anti-Inflammatory Agents; Conjunctivitis, Bacterial; Diagnosis, Differential; Emergency Medic

2006
[Progressive epidermal and mucosal skin lesions in a patient with rheumatoid arthritis].
    Praxis, 2007, May-16, Volume: 96, Issue:20

    Topics: Administration, Oral; Arthritis, Rheumatoid; Diagnosis, Differential; Dose-Response Relationship, Dr

2007
[Epidermolysis acuta toxica (Lyell)].
    Ceskoslovenska pediatrie, 1967, Volume: 22, Issue:6

    Topics: Child; Child, Preschool; Diagnosis, Differential; Female; Humans; Prednisone; Skin Diseases; Stevens

1967
Toxic epidermal necrolysis and malignant lymphoma.
    The British journal of dermatology, 1967, Volume: 79, Issue:5

    Topics: Adult; Aged; Bendroflumethiazide; Chloramphenicol; Cyclizine; Female; Hodgkin Disease; Humans; Lymph

1967
Adrenal corticosteroids in erythema multiforme.
    JAMA, 1982, Dec-03, Volume: 248, Issue:21

    Topics: Adrenal Cortex Hormones; Adult; Erythema Multiforme; Herpes Simplex; Humans; Male; Prednisone; Steve

1982
[Stevens-Johnson syndrome and pulmonary infection by Mycoplasma pneumoniae (author's transl)].
    Annales de pediatrie, 1981, Volume: 28, Issue:6

    Topics: Adolescent; Adult; Anti-Bacterial Agents; Child; Drug Therapy, Combination; Female; Humans; Male; Pn

1981
Stevens-Johnson syndrome associated with methotrexate treatment for non-Hodgkin's lymphoma.
    The Ulster medical journal, 1993, Volume: 62, Issue:1

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cyclophosphamide; Doxorubicin; Humans; Le

1993
[Toxic epidermal necrolysis].
    Ugeskrift for laeger, 1993, Jul-26, Volume: 155, Issue:30

    Topics: Glucocorticoids; Humans; Prednisone; Stevens-Johnson Syndrome

1993
Stevens-Johnson syndrome associated with herpes simplex virus.
    Archives of internal medicine, 1993, Jun-14, Volume: 153, Issue:11

    Topics: Herpes Labialis; Humans; Male; Prednisone; Recurrence; Stevens-Johnson Syndrome; Stomatitis, Herpeti

1993
Reversal of erythema multiforme major with cyclophosphamide and prednisone.
    The Annals of pharmacotherapy, 1996, Volume: 30, Issue:6

    Topics: Adult; Alkylating Agents; Anti-Infective Agents, Urinary; Anti-Inflammatory Agents; Cyclophosphamide

1996
Drug-associated acute-onset vanishing bile duct and Stevens-Johnson syndromes in a child.
    Gastroenterology, 1998, Volume: 115, Issue:3

    Topics: Acute Disease; Adult; Bile Duct Diseases; Biopsy; Child; Cholestasis; Female; Humans; Ibuprofen; Liv

1998
Severe hypersensitivity reactions to allopurinol.
    Southern medical journal, 1979, Volume: 72, Issue:11

    Topics: Adult; Aged; Allopurinol; Chemical and Drug Induced Liver Injury; Dermatitis, Exfoliative; Drug Erup

1979
Allopurinol sensitivity: report of two cases.
    American journal of hospital pharmacy, 1979, Volume: 36, Issue:10

    Topics: Aged; Allopurinol; Chemical and Drug Induced Liver Injury; Drug Eruptions; Drug Hypersensitivity; Hu

1979
Bullous impetigo. Occurrence of localized scalded skin syndrome in an adult.
    Archives of dermatology, 1976, Volume: 112, Issue:6

    Topics: Diagnosis, Differential; Female; Humans; Immunosuppression Therapy; Impetigo; Prednisone; Skin Disea

1976
Toxic epidermal necrolysis. A review of 75 cases in children.
    Archives of dermatology, 1975, Volume: 111, Issue:9

    Topics: Ampicillin; Child, Preschool; Dicloxacillin; Erythromycin; Female; Humans; Infant; Infant, Newborn;

1975
Herpes simplex virus associated with recurrent Stevens-Johnson syndrome. A management strategy.
    Archives of internal medicine, 1992, Volume: 152, Issue:7

    Topics: Acyclovir; Adult; Humans; Male; Prednisone; Recurrence; Stevens-Johnson Syndrome; Stomatitis, Herpet

1992
Unusual manifestation of Stevens-Johnson syndrome involving the respiratory and gastrointestinal tract.
    Pediatrics, 1992, Volume: 89, Issue:3

    Topics: Child; Chronic Disease; Esophageal Stenosis; Female; Humans; Prednisone; Radiography; Respiration Di

1992
[Your dog has TEN... Toxic epidermal necrolysis in the dog].
    Tijdschrift voor diergeneeskunde, 1991, Nov-01, Volume: 116, Issue:21

    Topics: Amoxicillin; Animals; Clavulanic Acids; Dog Diseases; Dogs; Drug Therapy, Combination; Female; Male;

1991
Drug-induced toxic epidermal necrolysis treated with cyclosporin.
    International journal of dermatology, 1989, Volume: 28, Issue:7

    Topics: Adult; Cyclosporins; Female; Humans; Methylprednisolone; Phenytoin; Prednisone; Stevens-Johnson Synd

1989
Erythema multiforme after use of topical sulfacetamide.
    American journal of ophthalmology, 1985, Apr-15, Volume: 99, Issue:4

    Topics: Child; Conjunctivitis; Drug Eruptions; Drug Hypersensitivity; Erythromycin; Humans; Male; Nafcillin;

1985
Toxic epidermal necrolysis from griseofulvin.
    Journal of the American Academy of Dermatology, 1988, Volume: 19, Issue:3

    Topics: Adult; Female; Griseofulvin; Humans; Prednisone; Stevens-Johnson Syndrome

1988
Toxic epidermal necrolysis in a patient affected by mixed essential cryoglobulinemia.
    Journal of the American Academy of Dermatology, 1988, Volume: 18, Issue:5 Pt 2

    Topics: Complement C4; Cryoglobulinemia; Cyclophosphamide; Diagnosis, Differential; Humans; Immunoglobulin G

1988
Drug-induced toxic epidermal necrolysis.
    The British journal of dermatology, 1985, Volume: 113, Issue:5

    Topics: Antibody-Dependent Cell Cytotoxicity; Graft vs Host Reaction; Humans; Hypersensitivity, Delayed; Pre

1985
[Two cases of Lyell's syndrome (toxic epidermal necrosis) in children].
    Revue medicale de la Suisse romande, 1972, Volume: 92, Issue:12

    Topics: Aspirin; Child; Drug Hypersensitivity; gamma-Globulins; Humans; Male; Penicillins; Prednisone; Steve

1972
Toxic epidermal necrolysis and Stevens-Johnson's disease.
    Acta dermato-venereologica, 1966, Volume: 46, Issue:2

    Topics: Adult; Blood Transfusion; Chlorpromazine; Diagnosis, Differential; Female; Humans; Immunization, Pas

1966
[Necrolytic exanthemas caused by drugs].
    Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete, 1968, Volume: 19, Issue:1

    Topics: Adult; Child, Preschool; Diagnosis, Differential; Drug Eruptions; Drug Hypersensitivity; Erythema; E

1968
Toxic epidermal necrolysis in a patient with graft-vs-host reaction.
    Archives of dermatology, 1972, Volume: 105, Issue:4

    Topics: Adult; Anti-Bacterial Agents; Basement Membrane; Biopsy; Bone Marrow Cells; Bone Marrow Transplantat

1972
Treatment of staphylococcal toxic epidermal necrolysis.
    Archives of dermatology, 1974, Volume: 110, Issue:4

    Topics: Administration, Oral; Anti-Bacterial Agents; Child, Preschool; Cortisone; Dexamethasone; Dicloxacill

1974
Renal disease associated with toxic epidermal necrolysis (Lyell's disease).
    The American journal of medicine, 1974, Volume: 57, Issue:5

    Topics: Adult; Azathioprine; Biopsy; Blood Urea Nitrogen; Cholesterol; Creatinine; Female; Glomerulonephriti

1974
Blood lymphoblast proliferation in vivo in cutaneous drug hypersensitivity reactions.
    International archives of allergy and applied immunology, 1974, Volume: 46, Issue:2

    Topics: Blood Cell Count; Carbamazepine; Chlorpromazine; Drug Hypersensitivity; Exanthema; Humans; Lymphocyt

1974
Further experiences of toxic epidermal necrolysis incriminating allopurinol, pyrazolone and derivatives.
    The British journal of dermatology, 1972, Volume: 86, Issue:6

    Topics: Adult; Aged; Allopurinol; Biopsy; Female; Humans; Male; Middle Aged; Prednisone; Prognosis; Pyrazole

1972
[Lyell Epidermolysis in exudative psoriasis].
    Zeitschrift fur Haut- und Geschlechtskrankheiten, 1967, May-15, Volume: 42, Issue:10

    Topics: Drug Hypersensitivity; Female; Humans; Middle Aged; Prednisone; Psoriasis; Pyrazoles; Skin Tests; St

1967
[On the problem of dermarcation of the Lyell's syndrome].
    Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete, 1967, Volume: 18, Issue:11

    Topics: Dermatitis Herpetiformis; Diagnosis, Differential; Female; Humans; Middle Aged; Pemphigus; Prednison

1967
[Toxic epidermal necrolysis].
    Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 1969, Mar-15, Volume: 89, Issue:6

    Topics: Adult; Anti-Bacterial Agents; Female; Humans; Infusions, Parenteral; Meprobamate; Middle Aged; Ointm

1969
[Epidermolysis acuta toxica (Lyell) following phenylbutazone intake, with subsequent keratomalacia].
    Das Deutsche Gesundheitswesen, 1966, May-19, Volume: 21, Issue:20

    Topics: Adult; Aged; Anti-Bacterial Agents; Cornea; Eye Diseases; Female; Humans; Male; Middle Aged; Phenylb

1966