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prednisone and Disease Models, Animal

prednisone has been researched along with Disease Models, Animal in 99 studies

Prednisone: A synthetic anti-inflammatory glucocorticoid derived from CORTISONE. It is biologically inert and converted to PREDNISOLONE in the liver.
prednisone : A synthetic glucocorticoid drug that is particularly effective as an immunosuppressant, and affects virtually all of the immune system. Prednisone is a prodrug that is converted by the liver into prednisolone (a beta-hydroxy group instead of the oxo group at position 11), which is the active drug and also a steroid.

Disease Models, Animal: Naturally-occurring or experimentally-induced animal diseases with pathological processes analogous to human diseases.

Research Excerpts

ExcerptRelevanceReference
" Here we generated a single-cell transcriptional immune cell atlas based on prednisone-treated or untreated experimental autoimmune uveitis (EAU) mice."8.02Prednisone Reprograms the Transcriptional Immune Cell Landscape in CNS Autoimmune Disease. ( Chen, B; Duan, R; Gao, Y; Li, H; Li, Z; Su, W; Wang, R; Wang, X; Xie, L; Zhu, L, 2021)
" However, the role of Cav-1 expression in pirfenidone-treated idiopathic pulmonary fibrosis (IPF) is unknown."7.85Effects and mechanisms of pirfenidone, prednisone and acetylcysteine on pulmonary fibrosis in rat idiopathic pulmonary fibrosis models. ( Guo, F; Song, X; Yu, W, 2017)
"To investigate the effects of Artemisinin on the expressions of GRalpha mRNA, GRbeta mRNA and P300/CBP protein in lupus nephritis mice."7.78[Effect of artemisinin on the expressions of GRalpha mRNA, GRbeta mRNA and P300/CBP protein in lupus nephritis mice]. ( An, P; Qiao, CL; Shi, XM; Sun, WS; Wang, Z; Wu, XL, 2012)
"To investigate the therapeutic effects and mechanisms of using artemisinin (Art) combined with glucocorticoid (GC) to treat lupus nephritis (LN) mice."7.77Effect of artemisinin combined with glucocorticoid on the expressions of glucocorticoid receptor α mRNA, glucocorticoid receptor β mRNA and P300/CBP protein in lupus nephritis mice. ( An, P; Qiao, CL; Shi, XM; Sun, WS; Wang, Z; Wu, XL; Zhang, WG, 2011)
" The efficacy of immunosuppressive doses of oral prednisone to inhibit in-stent neointimal proliferation was compared with BMS and with a commercially available paclitaxel-eluting stent (Taxus) in a rabbit model of established atherosclerosis."7.74Effects of oral prednisone after stenting in a rabbit model of established atherosclerosis. ( Acampado, E; Crimins, J; Ferrero, V; Finn, AV; Joner, M; Kolodgie, FD; Nakazawa, G; Ribichini, F; Vassanelli, C; Virmani, R, 2007)
"Prednisone eliminated postoperative AFL, affected all EP parameters studied, and attenuated the inflammatory response associated with pericarditis."7.74Prednisone prevents inducible atrial flutter in the canine sterile pericarditis model. ( Goldstein, RN; Khrestian, C; Ryu, K; van Wagoner, DR; Waldo, AL, 2008)
"To evaluate the effect of Concanavalin A (Con A) on cataract formation in New Zealand Albino rabbits."7.68Concanavalin A-induced posterior subcapsular cataract: a new model of cataractogenesis. ( Cunanan, C; Gruber, L; Gwon, A; Mantras, C, 1993)
"The author presents evidence from published papers of research done by numerous investigators that Multiple, Sclerosis (MS) is an autoimmune disease, that the target tissue is the myelin sheath which covers the nerve fibers in the brain and spinal cord, that Myelin Basic Protein (MBP) is the antigen or one of the antigens involved, that the autoimmune reaction is effected by sensitized lymphocytes together with a specific antibody, that Experimental Allergic Encephalomyelitis (EAE) produced in animals can be used as a model for MS, and that the autoimmune reaction in MS can possibly be suppressed by the use of MBP given by an intravenous procedure together with an immunosuppressive drug and a corticosteroid."7.67Suppression of the immune reaction in multiple sclerosis might be achieved by intravenous injections of myelin basic protein, concomitant with the administration of an immunosuppressant and a corticosteroid. ( Eidinoff, H, 1988)
"The author presents evidence from published papers of research done by numerous investigators that Multiple Sclerosis (MS) is an autoimmune disease, that the target tissue is the myelin sheath which covers the nerve fibers in the brain and spinal cord, that Myelin Basic Protein (MBP) is the antigen or one of the antigens involved, that the autoimmune reaction is effected by sensitized lymphocytes together with a specific antibody, that Experimental Allergic Encephalomyelitis (EAE) produced in animals can be used as a model for MS, and that the autoimmune reaction in MS can possibly be suppressed by the use of MBP given by an intravenous procedure together with an immunosuppressive drug and a corticosteroid."7.67Suppression of the immune reaction in multiple sclerosis might be achieved by intravenous injections of myelin basic protein, concomitant with the administration of an immunosuppressant and a corticosteroid. ( Eidinoff, H, 1988)
"Diarrhea is the gastrointestinal disease most frequently encountered in captive rhesus macaques."5.35Effects of the macrolide drug tylosin on chronic diarrhea in rhesus macaques (Macaca mulatta). ( Blackwood, RS; Christe, KL; Lerche, NW; Spinner, A; Tarara, RP, 2008)
" Here we generated a single-cell transcriptional immune cell atlas based on prednisone-treated or untreated experimental autoimmune uveitis (EAU) mice."4.02Prednisone Reprograms the Transcriptional Immune Cell Landscape in CNS Autoimmune Disease. ( Chen, B; Duan, R; Gao, Y; Li, H; Li, Z; Su, W; Wang, R; Wang, X; Xie, L; Zhu, L, 2021)
"Combination therapy with mycophenolate mofetil, tacrolimus and steroids are effective in achieving complete remission in lupus nephritis (LN)."4.02Novel Effects of Combination Therapy Through Inhibition of Caspase-1/Gasdermin D Induced-Pyroptosis in Lupus Nephritis. ( Cao, H; He, Y; Jiang, S; Ke, Y; Liang, J; Lin, J; Liu, J; Sun, Y, 2021)
" Numerous clinical interventions, including those used to treat multiple sclerosis (MS), have confirmed prednisone (PDN) as a powerful anti-inflammatory drug that reduces the inflammatory response and promotes tissue repair in multiple inflammation sites."3.88Prednisone alleviates demyelination through regulation of the NLRP3 inflammasome in a C57BL/6 mouse model of cuprizone-induced demyelination. ( Cao, T; Chen, N; Fan, H; Jiang, Z; Lu, G; Wu, M; Yao, R; Yu, H; Zhang, Y, 2018)
"A recent clinical study showed that combination therapy consisting of mycophenolate mofetil, tacrolimus and steroids was shown to be more effective in achieving complete remission in patients with severe forms of lupus nephritis than conventional therapy consisting of intravenous cyclophosphamide and steroids."3.88Transcriptomic analysis uncovers novel synergistic mechanisms in combination therapy for lupus nephritis. ( Cai, M; Chuang, PY; Fu, J; He, JC; Lee, K; Liu, Z; Ma'ayan, A; Wang, Z; Wei, C; Zhang, M; Zhang, W; Zhou, M, 2018)
" However, the role of Cav-1 expression in pirfenidone-treated idiopathic pulmonary fibrosis (IPF) is unknown."3.85Effects and mechanisms of pirfenidone, prednisone and acetylcysteine on pulmonary fibrosis in rat idiopathic pulmonary fibrosis models. ( Guo, F; Song, X; Yu, W, 2017)
" acidophilus and prednisone acetate) protected against colitis-induced weight loss (P < 0."3.79Efficacy profiles for different concentrations of Lactobacillus acidophilus in experimental colitis. ( Chen, LL; Li, FJ; Lian, GH; Lu, FG; Zou, YY, 2013)
"To investigate the effects of Artemisinin on the expressions of GRalpha mRNA, GRbeta mRNA and P300/CBP protein in lupus nephritis mice."3.78[Effect of artemisinin on the expressions of GRalpha mRNA, GRbeta mRNA and P300/CBP protein in lupus nephritis mice]. ( An, P; Qiao, CL; Shi, XM; Sun, WS; Wang, Z; Wu, XL, 2012)
"To investigate the therapeutic effects and mechanisms of using artemisinin (Art) combined with glucocorticoid (GC) to treat lupus nephritis (LN) mice."3.77Effect of artemisinin combined with glucocorticoid on the expressions of glucocorticoid receptor α mRNA, glucocorticoid receptor β mRNA and P300/CBP protein in lupus nephritis mice. ( An, P; Qiao, CL; Shi, XM; Sun, WS; Wang, Z; Wu, XL; Zhang, WG, 2011)
" The efficacy of immunosuppressive doses of oral prednisone to inhibit in-stent neointimal proliferation was compared with BMS and with a commercially available paclitaxel-eluting stent (Taxus) in a rabbit model of established atherosclerosis."3.74Effects of oral prednisone after stenting in a rabbit model of established atherosclerosis. ( Acampado, E; Crimins, J; Ferrero, V; Finn, AV; Joner, M; Kolodgie, FD; Nakazawa, G; Ribichini, F; Vassanelli, C; Virmani, R, 2007)
"Prednisone eliminated postoperative AFL, affected all EP parameters studied, and attenuated the inflammatory response associated with pericarditis."3.74Prednisone prevents inducible atrial flutter in the canine sterile pericarditis model. ( Goldstein, RN; Khrestian, C; Ryu, K; van Wagoner, DR; Waldo, AL, 2008)
"To evaluate the effect of Concanavalin A (Con A) on cataract formation in New Zealand Albino rabbits."3.68Concanavalin A-induced posterior subcapsular cataract: a new model of cataractogenesis. ( Cunanan, C; Gruber, L; Gwon, A; Mantras, C, 1993)
"The author presents evidence from published papers of research done by numerous investigators that Multiple, Sclerosis (MS) is an autoimmune disease, that the target tissue is the myelin sheath which covers the nerve fibers in the brain and spinal cord, that Myelin Basic Protein (MBP) is the antigen or one of the antigens involved, that the autoimmune reaction is effected by sensitized lymphocytes together with a specific antibody, that Experimental Allergic Encephalomyelitis (EAE) produced in animals can be used as a model for MS, and that the autoimmune reaction in MS can possibly be suppressed by the use of MBP given by an intravenous procedure together with an immunosuppressive drug and a corticosteroid."3.67Suppression of the immune reaction in multiple sclerosis might be achieved by intravenous injections of myelin basic protein, concomitant with the administration of an immunosuppressant and a corticosteroid. ( Eidinoff, H, 1988)
"The author presents evidence from published papers of research done by numerous investigators that Multiple Sclerosis (MS) is an autoimmune disease, that the target tissue is the myelin sheath which covers the nerve fibers in the brain and spinal cord, that Myelin Basic Protein (MBP) is the antigen or one of the antigens involved, that the autoimmune reaction is effected by sensitized lymphocytes together with a specific antibody, that Experimental Allergic Encephalomyelitis (EAE) produced in animals can be used as a model for MS, and that the autoimmune reaction in MS can possibly be suppressed by the use of MBP given by an intravenous procedure together with an immunosuppressive drug and a corticosteroid."3.67Suppression of the immune reaction in multiple sclerosis might be achieved by intravenous injections of myelin basic protein, concomitant with the administration of an immunosuppressant and a corticosteroid. ( Eidinoff, H, 1988)
"The pathogenesis of minimal change disease (MCD), considered to be the simplest form of nephrotic syndrome, has been one of the major unsolved mysteries in kidney disease."2.48New insights into human minimal change disease: lessons from animal models. ( Chugh, SS; Clement, LC; Macé, C, 2012)
"Asthma is characterized by airway remodeling."1.62Glucocorticoid induced transcript 1 represses airway remodeling of asthmatic mouse via inhibiting IL-13/periostin/TGF-β1 signaling. ( Kuang, J; Wang, W; Xun, Q; Yang, Q; Zhu, G, 2021)
"Neuropsychiatric systemic lupus erythematosus (NPSLE) is a common cause of disability in systemic lupus erythematosus (SLE)."1.56Analysis of brain metabolites by gas chromatography-mass spectrometry reveals the risk-benefit concerns of prednisone in MRL/lpr lupus mice. ( Li, S; Lu, F; Lu, H; Wang, S; Wen, C; Wu, D; Xie, M; Xie, Z; Xu, ZH; Zhou, J, 2020)
" Intermittent steroid dosing has been proposed in Duchenne Muscular Dystrophy patients to mitigate the side effects seen with daily steroid intake."1.51Pulsed glucocorticoids enhance dystrophic muscle performance through epigenetic-metabolic reprogramming. ( Barish, GD; Bass, J; Demonbreun, AR; Haldar, SM; Jiang, Z; Kuntz, NL; McNally, EM; Peek, CB; Quattrocelli, M; Zelikovich, AS, 2019)
"Corticosteroids are highly prescribed and effective anti-inflammatory drugs but the burden of side effects with chronic use significantly detracts from patient quality of life, particularly in children."1.48Muscle miRNAome shows suppression of chronic inflammatory miRNAs with both prednisone and vamorolone. ( Damsker, JM; Fiorillo, AA; Heier, CR; Hoffman, EP; Nagaraju, K; Tully, CB, 2018)
"Prednisone was the positive control in both studies."1.42Chronic Dosing with Membrane Sealant Poloxamer 188 NF Improves Respiratory Dysfunction in Dystrophic Mdx and Mdx/Utrophin-/- Mice. ( Kernodle, S; Markham, BE; Nemzek, J; Sigler, R; Wilkinson, JE, 2015)
"The prednisone-mediated increase in α7 integrin was associated with increased laminin-α2 in prednisone-treated dystrophin-deficient muscle."1.39Levels of α7 integrin and laminin-α2 are increased following prednisone treatment in the mdx mouse and GRMD dog models of Duchenne muscular dystrophy. ( Burkin, DJ; Kornegay, JN; Sarathy, A; Wuebbles, RD, 2013)
"Prednisone treatment significantly normalized the intensities of peaks 9069 and 15005 (which correspond to cortexin-1 and interleukin-17A, respectively, according to Swiss Prot database) by increasing the expression of 9069 but reducing expression of 15005."1.39Proteomic analysis indicates altered expression of plasma proteins in a rat nephropathy model. ( Ai, S; Chen, R; Lin, Q; Zheng, J, 2013)
"To determine the genetic susceptibility of rats to develop GC-induced femoral head ON, we evaluated 5 different inbred strains of rats (Spontaneous Hypertensive Rat, Wistar Kyoto, Wistar Furth, SASCO Fisher and Lewis)."1.37A rat model of early stage osteonecrosis induced by glucocorticoids. ( Chow, TY; Cournoyer, D; Harvey, EJ; Kerachian, MA; Nahal, A; Séguin, C, 2011)
"Arginine butyrate treatment improved grip strength and decreased fibrosis in the gastrocnemius muscle, but did not produce significant improvement in muscle and cardiac histology, heart function, behavioral measurements, or serum creatine kinase levels."1.36Functional and molecular effects of arginine butyrate and prednisone on muscle and heart in the mdx mouse model of Duchenne Muscular Dystrophy. ( Becker, M; Bossi, L; Cha, HJ; de la Porte, S; Escolar, DM; Farajian, V; Francia, D; Gernapudi, R; Gordish-Dressman, H; Guerron, AD; Hoffman, EP; Nagaraju, K; Pandey, GS; Partridge, T; Pistilli, E; Rawat, R; Sali, A; Spurney, CF; Zerr, P, 2010)
"Diarrhea is the gastrointestinal disease most frequently encountered in captive rhesus macaques."1.35Effects of the macrolide drug tylosin on chronic diarrhea in rhesus macaques (Macaca mulatta). ( Blackwood, RS; Christe, KL; Lerche, NW; Spinner, A; Tarara, RP, 2008)
"Duchenne muscular dystrophy is a degenerative muscular disease caused by mutations in the dystrophin gene."1.32Prednisone reduces muscle degeneration in dystrophin-deficient Caenorhabditis elegans. ( Carre-Pierrat, M; Gaud, A; Ségalat, L; Simon, JM; Wermuth, CG; Witzel, T, 2004)
"The aim of the study was to evaluate the effects of D-penicillamine (cuprenil), encorton and both drugs in combination on fibrotic processes in the rat liver damaged by chronic use of CCl4."1.28[Effects of D-penicillamine and encorton on the fibrotic processes in experimental liver cirrhosis in rats]. ( Czarnecki, J; Piecińska, T; Rubaj, B; Rubaj, M, 1990)
"Thalidomide treatment was successful in the majority of animals (16 of 18)."1.28Therapy of chronic graft-v-host disease in a rat model. ( Friedman, KJ; Hess, AD; Santos, GW; Vogelsang, GB, 1989)
"Prednisone may also suppress cartilage breakdown by either acting at the level of the synthesis or by acting on the release/action of the stimulating factors."1.27Role of synovial membrane inflammation in cartilage matrix breakdown in the Pond-Nuki dog model of osteoarthritis. ( Ghandur-Mnaymneh, L; Howell, DS; Martel-Pelletier, J; Pelletier, JP; Woessner, JF, 1985)
"In 50 to 60 percent of patients with systemic lupus erythematosus (SLE), a band of immunoglobulins beneath the epidermis of visibly normal skin."1.25The significance of cutaneous immunoglobulin deposits in lupus erythematosus and NZB/NZW F1 hybrid mice. ( Gilliam, JN, 1975)

Research

Studies (99)

TimeframeStudies, this research(%)All Research%
pre-199030 (30.30)18.7374
1990's6 (6.06)18.2507
2000's15 (15.15)29.6817
2010's38 (38.38)24.3611
2020's10 (10.10)2.80

Authors

AuthorsStudies
Abrams, RPM1
Yasgar, A1
Teramoto, T1
Lee, MH1
Dorjsuren, D1
Eastman, RT1
Malik, N1
Zakharov, AV1
Li, W1
Bachani, M1
Brimacombe, K1
Steiner, JP1
Hall, MD1
Balasubramanian, A1
Jadhav, A1
Padmanabhan, R1
Simeonov, A1
Nath, A1
Li, H2
Gao, Y1
Xie, L2
Wang, R1
Duan, R1
Li, Z1
Chen, B1
Zhu, L1
Wang, X6
Su, W1
Wang, M1
Zhu, Z1
Lin, X1
Wen, C3
Bao, J1
He, Z1
Kaviani, A1
Khansari Nejad, N1
Akour, A1
AlMuhaissen, SA1
Nusair, MB1
Al-Tammemi, AB1
Mahmoud, NN1
Jalouqa, S1
Alrawashdeh, MN1
Shanahan, JP1
Moore, CM1
Kampf, JW1
Szymczak, NK1
Guo, J1
Wang, H4
Luo, Y1
An, H1
Zhang, Z2
Liu, G2
Li, J1
Metcalfe, GD1
Smith, TW1
Hippler, M1
Ayala Izurieta, JE1
Márquez, CO1
García, VJ1
Jara Santillán, CA1
Sisti, JM1
Pasqualotto, N1
Van Wittenberghe, S1
Delegido, J1
Kubo, Y1
Kitagawa, Y1
Miyazaki, T1
Sohda, M1
Yamaji, T1
Sakai, M1
Saeki, H1
Nemoto, K1
Oyama, T2
Muto, M1
Takeuchi, H1
Toh, Y1
Matsubara, H1
Mano, M1
Kono, K1
Kato, K1
Yoshida, M1
Kawakubo, H1
Booka, E1
Yamatsuji, T1
Kato, H1
Ito, Y1
Ishikawa, H1
Ishihara, R1
Tsushima, T1
Kawachi, H1
Kojima, T1
Kuribayashi, S1
Makino, T1
Matsuda, S1
Doki, Y1
Ma, P1
Tang, X1
Zhang, L2
Wang, W2
Zhang, X1
Wang, S4
Zhou, N1
Dodd, J1
Jordan, R1
Makhlina, M1
Pesco Koplowitz, L1
Koplowitz, B1
Barnett, K1
Yang, WH1
Spana, C1
Buchanan, SW1
Mafa-Attoye, T1
Dunfield, K1
Thevathasan, NV1
Isaac, ME1
Wu, X2
Huang, JW1
Su, BK1
Yuan, L1
Zheng, WQ1
Zhang, H2
Zheng, YX1
Zhu, W1
Chou, PT1
Manso, AP1
De Morais, DC1
Yamamoto, K1
Owen, G1
de Carvalho, RM1
Palma-Dibb, RG1
Brown, JC1
Yang, S1
Mire, EF1
Miele, L1
Ochoa, A1
Zabaleta, J1
Katzmarzyk, PT1
Moi, CT1
Bhowmick, S1
Qureshi, M1
Wang, K3
Feng, B1
Yang, Y1
Chen, Y1
Wang, Y2
Yang, L1
Jiang, K1
James, TD1
Chaturvedi, V1
Postiglione, WM1
Chakraborty, RD1
Yu, B1
Tabiś, W1
Hameed, S1
Biniskos, N1
Jacobson, A1
Zhou, H1
Greven, M1
Ferry, VE1
Leighton, C1
Wu, F1
Lei, H1
Chen, G1
Chen, C1
Song, Y1
Cao, Z1
Zhang, C2
Zhou, J3
Lu, Y2
Pappone, C1
Santinelli, V1
Mecarocci, V1
Tondi, L1
Ciconte, G1
Manguso, F1
Sturla, F1
Vicedomini, G1
Micaglio, E1
Anastasia, L1
Pica, S1
Camporeale, A1
Lombardi, M1
Shieh, PB1
Elfring, G1
Trifillis, P1
Santos, C1
Peltz, SW1
Parsons, JA1
Apkon, S1
Darras, BT1
Campbell, C1
McDonald, CM1
Galaviz, KI1
Shah, NS1
Gutierrez, M1
Collins, LF1
Lahiri, CD1
Moran, CA1
Szabo, B1
Sumitani, J1
Rhodes, J1
Marconi, VC1
Nguyen, ML1
Cantos, VD1
Armstrong, WS1
Colasanti, JA1
Zareie, F1
Ghalebandi, S1
Askari, K1
Mousavi, Z1
Haghparast, A1
Gong, K1
Guo, G1
Beckley, NA1
Yang, X1
Zhang, Y2
Gerber, DE1
Minna, JD1
Burma, S1
Zhao, D1
Akbay, EA1
Habib, AA1
Cao, H2
Liang, J1
Liu, J1
He, Y1
Ke, Y1
Sun, Y1
Jiang, S1
Lin, J1
Lu, F2
Li, S2
Xie, M2
Lu, H2
Xie, Z1
Wu, D1
Xu, ZH1
Quattrocelli, M1
Zelikovich, AS1
Jiang, Z2
Peek, CB1
Demonbreun, AR1
Kuntz, NL1
Barish, GD1
Haldar, SM1
Bass, J1
McNally, EM1
Tomazoni, SS1
Casalechi, HL1
Ferreira, CSB1
Serra, AJ1
Dellê, H1
Brito, RBO1
de Melo, BL1
Vanin, AA1
Ribeiro, NF1
Pereira, AL1
Monteiro, KKDS1
Marcos, RL1
de Carvalho, PTC1
Frigo, L1
Leal-Junior, ECP1
Xun, Q1
Kuang, J1
Yang, Q1
Zhu, G1
Zheng, C1
Xu, X1
Zhao, Y1
Liu, Z3
Zhao, X1
Qi, X1
Wang, C1
Zhou, Z1
Wu, P1
Li, L1
Lu, S1
Wang, Z4
Yu, H1
Wu, M1
Lu, G1
Cao, T1
Chen, N1
Fan, H1
Yao, R1
Fu, J1
Lee, K1
Wei, C1
Zhang, M2
Zhou, M1
Cai, M1
Zhang, W1
Chuang, PY1
Ma'ayan, A1
He, JC1
Zhong, X1
Liu, D1
Liu, L1
Xia, Z1
Fiorillo, AA1
Tully, CB1
Damsker, JM1
Nagaraju, K2
Hoffman, EP2
Heier, CR1
Zhang, J1
Li, Q1
Shao, Q1
Song, J1
Zhou, B1
Shu, P1
Liu, Y2
Jia, Z1
Akhter, MP2
Gao, X2
Zhao, G2
Wei, X2
Zhou, Y2
Hartman, CW1
Fehringer, EV1
Cui, L3
Wang, D2
Liu, YZ1
Wang, XY1
Wang, XB1
Wu, HJ1
Chen, H1
Feng, T1
Guo, D1
Chen, L1
DeWeerdt, S1
Chen, R2
Zhang, Q1
Chen, S1
Tang, H1
Huang, P1
Wei, S1
Liang, Z1
Chen, X1
Tao, A1
Yao, L1
Zahn, NM1
Huber, AT1
Mikulsky, BN1
Stepanski, ME1
Kehoe, AS1
Li, G2
Schussman, M1
Rashid Roni, MS1
Kodali, R1
Cook, JM1
Stafford, DC1
Steeber, DA1
Arnold, LA1
Zu, Y1
Yu, J1
Ruan, Y1
Xu, Z1
Wuebbles, RD1
Sarathy, A1
Kornegay, JN1
Burkin, DJ1
Chen, LL1
Zou, YY1
Lu, FG1
Li, FJ1
Lian, GH1
Clarke, DL1
Davis, NH1
Majithiya, JB1
Piper, SC1
Lewis, A1
Sleeman, MA1
Corkill, DJ1
May, RD1
Lin, S1
Huang, J1
Zheng, L1
Li, N1
Zou, L1
Wu, T1
Qin, L1
Markham, BE1
Kernodle, S1
Nemzek, J1
Wilkinson, JE1
Sigler, R1
Chen, F1
Ma, YL1
Ding, H1
Chen, BP1
Sinha, S1
Uchibe, K1
Usami, Y1
Pacifici, M1
Iwamoto, M1
Carli, AV1
Harvey, EJ2
Azeddine, B1
Gao, C1
Li, Y1
Li, A1
Sayegh, M1
Nahal, A2
Michel, RP1
Henderson, JE1
Séguin, C2
Klanova, M1
Soukup, T1
Molinsky, J1
Lateckova, L1
Vockova, P1
Alam, M1
Zivny, J1
Trneny, M1
Klener, P1
Karau, MJ1
Greenwood-Quaintance, KE1
Block, DR1
Mandrekar, JN1
Cunningham, SA1
Patel, R1
Yu, W1
Guo, F1
Song, X1
Yokote, Y1
Kimura, E1
Kimura, M1
Kozono, Y1
Tankéré, F1
Bernat, I1
Blackwood, RS1
Tarara, RP1
Christe, KL1
Spinner, A1
Lerche, NW1
Guerron, AD1
Rawat, R1
Sali, A1
Spurney, CF1
Pistilli, E1
Cha, HJ1
Pandey, GS1
Gernapudi, R1
Francia, D1
Farajian, V1
Escolar, DM1
Bossi, L1
Becker, M1
Zerr, P1
de la Porte, S1
Gordish-Dressman, H1
Partridge, T1
Sharma, N1
Moeller, CW1
Marzo, SJ1
Jones, KJ1
Foecking, EM1
Kaplan, FS1
Pignolo, RJ1
Shore, EM1
Bouazzaoui, A1
Spacenko, E1
Mueller, G1
Huber, E1
Schubert, T1
Holler, E1
Andreesen, R1
Hildebrandt, GC1
Wu, XL2
Zhang, WG1
Shi, XM2
An, P2
Sun, WS2
Qiao, CL2
Chugh, SS1
Clement, LC1
Macé, C1
Kerachian, MA1
Cournoyer, D1
Chow, TY1
Keel, SB1
Phelps, S1
Sabo, KM1
O'Leary, MN1
Kirn-Safran, CB1
Abkowitz, JL1
Ai, S1
Zheng, J1
Lin, Q1
Garber, K1
Oskooii, AE1
Gholizad, LM1
Zare, S1
Nejati, V1
Han, JK1
Woodson, BT1
Gaud, A1
Simon, JM1
Witzel, T1
Carre-Pierrat, M1
Wermuth, CG1
Ségalat, L1
De Luca, A1
Vossen, M1
Majzoub, RK1
Edelstein, J1
Perez-Abadia, G1
Voor, M1
Maldonado, C1
Tecimer, T1
Jevans, AW1
Zdichavsky, M1
Frank, JM1
Francois, C1
Kon, M1
Barker, JH1
Zhang, HQ1
Yau, YF1
Szeto, KY1
Chan, WT1
Wong, J1
Li, M1
Gomes, AT1
Cunha, LM1
Bastos, CG1
Medrado, BF1
Assis, BC1
Andrade, ZA1
Xiong, M1
Dang, X1
Ribichini, F1
Joner, M1
Ferrero, V1
Finn, AV1
Crimins, J1
Nakazawa, G1
Acampado, E1
Kolodgie, FD1
Vassanelli, C1
Virmani, R1
Goldstein, RN1
Ryu, K1
Khrestian, C1
van Wagoner, DR1
Waldo, AL1
Marcus, GM1
Scheinman, MM1
Aguila, B1
Coulbault, L1
Boulouard, M1
Léveillé, F1
Davis, A1
Tóth, G1
Borsodi, A1
Balboni, G1
Salvadori, S1
Jauzac, P1
Allouche, S1
Abramsky, O1
Seybold, ME1
Harper, JS2
Genta, RM2
Gam, A1
London, WT1
Neva, FA2
Gam, AA1
London, WI1
Ginzler, EM1
Bollet, AJ1
Friedman, EA1
Hogenesch, H1
Snyder, PW1
Scott-Moncrieff, JC1
Glickman, LT1
Felsburg, PJ1
Gwon, A1
Mantras, C1
Gruber, L1
Cunanan, C1
Mizuno, S1
Mizuno-Horikawa, Y1
Yue, BF1
Okamoto, M1
Kurosawa, T1
Bohm, RP1
Dennis, V1
Blanchard, JL1
Philipp, MT1
Gerber, MA1
Madsen, LW1
Aalbaek, B1
Nielsen, OL1
Jensen, HE1
Croft, CB1
Zub, K1
Borowiecki, B1
Metheny, JA1
DeVita, VT1
Gilliam, JN1
Galus, K1
Tałałaj, M1
Smogorzewski, M1
Madej, K1
Karolak, M1
Wall, W1
Rubaj, M1
Czarnecki, J1
Rubaj, B1
Piecińska, T1
Eidinoff, H2
Vogelsang, GB1
Hess, AD1
Friedman, KJ1
Santos, GW1
Pelletier, JP1
Martel-Pelletier, J1
Ghandur-Mnaymneh, L1
Howell, DS1
Woessner, JF1
Goldberg, AI1
Glynn, JP1
Kende, M1
Mantel, N1
Goldin, A3
Burns, RP1
Beard, ME1
Weimar, VL1
Squires, EL1
Underwood, GE1
Weed, SD1
Schabel, FM2
Skipper, HE1
Trader, MW1
Laster, WR1
Cheeks, JB1
Frei, E2
Flindall, RJ1
Leonard, BC1
Squire, RA1
Bush, M1
Melby, EC1
Neeley, LM1
Yarbrough, B1
Robertson, JH1
Crozier, EH1
Hollinger, M1
Black, DA1
Nowakowski, A1
Grove, RB1
King, LH1
Antonovych, TT1
Fortner, RW1
Knieser, MR1
Carter, CB1
Knepshield, JH1
Klastersky, J1
Sandberg, JS1
Henderson, ES1
Newman, JW1
Holland, JF1
Mielens, ZE1
Komarek, A1
Dietrich, FM1
Zubrod, CG1
Halawani, A1
Selim, MS1
Abddallah, AA1
D'Alena, P1
Okumoto, M1
Crawford, B1

Clinical Trials (4)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Evaluating the Impact of Aerobic Exercise in Boys With Duchenne Muscular Dystrophy (DMD)[NCT03319030]43 participants (Actual)Observational2017-09-01Completed
A Phase II Open-Label, Multiple Dose Study to Assess the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Exploratory Efficacy of Vamorolone in Boys Ages 2 to <4 Years and 7 to <18 Years With Duchenne Muscular Dystrophy (DMD)[NCT05185622]Phase 254 participants (Anticipated)Interventional2022-03-21Recruiting
A Phase II Pilot Trial of Vamorolone vs. Placebo for the Treatment of Becker Muscular Dystrophy[NCT05166109]Phase 239 participants (Anticipated)Interventional2022-07-07Recruiting
Clinical and Angiographic Outcome of Patients Treated With Bare Metal Stent (BMS) Implantation Compared With Drug Eluting Stents or BMS Plus Systemic Prednisone Therapy. A Randomized, Multicentre Study.[NCT00369356]Phase 2/Phase 3375 participants (Actual)Interventional2006-10-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

11 reviews available for prednisone and Disease Models, Animal

ArticleYear
    Biomaterial investigations in dentistry, 2021, Volume: 8, Issue:1

    Topics: Adult; Alcohol Drinking; Ammonia; Animals; Anti-Inflammatory Agents; Area Under Curve; B-Lymphocytes

2021
[Bell's palsy: from viral aetiology to diagnostic reality].
    La Revue de medecine interne, 2009, Volume: 30, Issue:9

    Topics: Acyclovir; Administration, Oral; Adrenal Cortex Hormones; Animals; Anti-Inflammatory Agents; Antivir

2009
New insights into human minimal change disease: lessons from animal models.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 2012, Volume: 59, Issue:2

    Topics: Angiopoietin-Like Protein 4; Angiopoietins; Animals; Disease Models, Animal; Glucocorticoids; Humans

2012
Myasthenia gravis and acetylcholine receptor: autoimmunity and steroid effects.
    International journal of neurology, 1980, Volume: 14, Issue:1

    Topics: Adrenal Cortex Hormones; Animals; Autoantibodies; Autoimmune Diseases; Disease Models, Animal; Human

1980
Myasthenia gravis. A clinical and basic science review.
    JAMA, 1983, Nov-11, Volume: 250, Issue:18

    Topics: Adrenal Cortex Hormones; Adult; Animals; Autoantibodies; Child; Disease Models, Animal; Electromyogr

1983
The natural history and response to therapy of lupus nephritis.
    Annual review of medicine, 1980, Volume: 31

    Topics: Animals; Azathioprine; Clinical Trials as Topic; Cyclophosphamide; Disease Models, Animal; Fluoresce

1980
Dermatomyositis: a vocal and swallowing disease entity.
    The Laryngoscope, 1978, Volume: 88, Issue:1 Pt 1

    Topics: Adolescent; Adult; Aged; Animals; Child; Child, Preschool; Deglutition Disorders; Dermatomyositis; D

1978
Human models of human diseases; breast cancer and the lymphomas.
    International journal of radiation oncology, biology, physics, 1979, Volume: 5, Issue:10

    Topics: Animals; Antineoplastic Agents; Breast Neoplasms; Disease Models, Animal; Drug Therapy, Combination;

1979
Immunosuppressive agents in protein-losing nephritis.
    The Scientific basis of medicine annual reviews, 1970

    Topics: Animals; Azathioprine; Cyclophosphamide; Disease Models, Animal; Glomerulonephritis; Humans; Hyperse

1970
Effectiveness of adrenal corticosteroids in the management of severe bacterial infections.
    Revue europeenne d'etudes cliniques et biologiques. European journal of clinical and biological research, 1971, Volume: 16, Issue:5

    Topics: Adrenal Glands; Animals; Anti-Bacterial Agents; Bacterial Infections; Betamethasone; Brain Edema; Ce

1971
The chemotherapy of human and animal acute leukemia.
    Cancer chemotherapy reports, 1971, Volume: 55, Issue:4

    Topics: Animals; Antibiotics, Antineoplastic; Antineoplastic Agents; Asparaginase; Azaserine; Cell Division;

1971

Trials

3 trials available for prednisone and Disease Models, Animal

ArticleYear
The natural history and response to therapy of lupus nephritis.
    Annual review of medicine, 1980, Volume: 31

    Topics: Animals; Azathioprine; Clinical Trials as Topic; Cyclophosphamide; Disease Models, Animal; Fluoresce

1980
Therapy of iatrogenic subglottic stenosis: a steroid/antibiotic regimen.
    The Laryngoscope, 1979, Volume: 89, Issue:3

    Topics: Aged; Animals; Clinical Trials as Topic; Disease Models, Animal; Female; Glottis; Humans; Iatrogenic

1979
The chemotherapy of human and animal acute leukemia.
    Cancer chemotherapy reports, 1971, Volume: 55, Issue:4

    Topics: Animals; Antibiotics, Antineoplastic; Antineoplastic Agents; Asparaginase; Azaserine; Cell Division;

1971

Other Studies

87 other studies available for prednisone and Disease Models, Animal

ArticleYear
Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors.
    Proceedings of the National Academy of Sciences of the United States of America, 2020, 12-08, Volume: 117, Issue:49

    Topics: Animals; Antiviral Agents; Artificial Intelligence; Chlorocebus aethiops; Disease Models, Animal; Dr

2020
Prednisone Reprograms the Transcriptional Immune Cell Landscape in CNS Autoimmune Disease.
    Frontiers in immunology, 2021, Volume: 12

    Topics: Animals; Autoimmune Diseases; B-Lymphocytes; Disease Models, Animal; Gene Expression Profiling; Gene

2021
Gut microbiota mediated the therapeutic efficacies and the side effects of prednisone in the treatment of MRL/lpr mice.
    Arthritis research & therapy, 2021, 09-14, Volume: 23, Issue:1

    Topics: Animals; Disease Models, Animal; Gastrointestinal Microbiome; Glucocorticoids; Lupus Erythematosus,

2021
Orexin receptors in the CA1 region of hippocampus modulate the stress-induced antinociceptive responses in an animal model of persistent inflammatory pain.
    Peptides, 2022, Volume: 147

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Benzoxazoles; CA1 Region, Hippocampal; Cycl

2022
Comprehensive targeting of resistance to inhibition of RTK signaling pathways by using glucocorticoids.
    Nature communications, 2021, 12-01, Volume: 12, Issue:1

    Topics: A549 Cells; Animals; Carcinoma, Non-Small-Cell Lung; Cytokines; Disease Models, Animal; Drug Resista

2021
Novel Effects of Combination Therapy Through Inhibition of Caspase-1/Gasdermin D Induced-Pyroptosis in Lupus Nephritis.
    Frontiers in immunology, 2021, Volume: 12

    Topics: Adolescent; Adult; Aged; Animals; Calcineurin Inhibitors; Caspase 1; Caspase Inhibitors; Cells, Cult

2021
Analysis of brain metabolites by gas chromatography-mass spectrometry reveals the risk-benefit concerns of prednisone in MRL/lpr lupus mice.
    Inflammopharmacology, 2020, Volume: 28, Issue:2

    Topics: Animals; Brain; Disease Models, Animal; Female; Gas Chromatography-Mass Spectrometry; Glucocorticoid

2020
Pulsed glucocorticoids enhance dystrophic muscle performance through epigenetic-metabolic reprogramming.
    JCI insight, 2019, 12-19, Volume: 4, Issue:24

    Topics: Anacardic Acids; Animals; Biomarkers; Child; Cross-Sectional Studies; Disease Models, Animal; Drug T

2019
Can photobiomodulation therapy be an alternative to pharmacological therapies in decreasing the progression of skeletal muscle impairments of mdx mice?
    PloS one, 2020, Volume: 15, Issue:8

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Combined Modality Therapy; Disease Models, Animal;

2020
Glucocorticoid induced transcript 1 represses airway remodeling of asthmatic mouse via inhibiting IL-13/periostin/TGF-β1 signaling.
    International immunopharmacology, 2021, Volume: 97

    Topics: Airway Remodeling; Aluminum Hydroxide; Animals; Asthma; Cell Adhesion Molecules; Disease Models, Ani

2021
Fibrinogen links podocyte injury with Toll-like receptor 4 and is associated with disease activity in FSGS patients.
    Nephrology (Carlton, Vic.), 2018, Volume: 23, Issue:5

    Topics: Actin Cytoskeleton; Adolescent; Adult; Albuminuria; Animals; Apoptosis; Cell Line; Disease Models, A

2018
Idiopathic thrombocytopenic purpura: pathogenesis and potential therapeutic approach.
    Minerva medica, 2017, Volume: 108, Issue:6

    Topics: Adult; Aged; Animals; Disease Models, Animal; Drugs, Chinese Herbal; Enzyme-Linked Immunosorbent Ass

2017
Prednisone alleviates demyelination through regulation of the NLRP3 inflammasome in a C57BL/6 mouse model of cuprizone-induced demyelination.
    Brain research, 2018, Jan-01, Volume: 1678

    Topics: Animals; Astrocytes; Corpus Callosum; Cuprizone; Cytokines; Demyelinating Diseases; Disease Models,

2018
Transcriptomic analysis uncovers novel synergistic mechanisms in combination therapy for lupus nephritis.
    Kidney international, 2018, Volume: 93, Issue:2

    Topics: Animals; Cytoskeleton; Disease Models, Animal; Drug Synergism; Drug Therapy, Combination; Female; Ge

2018
The effects of freeze-dried Ganoderma lucidum mycelia on a recurrent oral ulceration rat model.
    BMC complementary and alternative medicine, 2017, Dec-01, Volume: 17, Issue:1

    Topics: Animals; Biological Products; Cytokines; Disease Models, Animal; Forkhead Transcription Factors; Fre

2017
Muscle miRNAome shows suppression of chronic inflammatory miRNAs with both prednisone and vamorolone.
    Physiological genomics, 2018, 09-01, Volume: 50, Issue:9

    Topics: Animals; Base Sequence; Chronic Disease; Disease Models, Animal; Gene Expression Regulation; Inflamm

2018
Muscle miRNAome shows suppression of chronic inflammatory miRNAs with both prednisone and vamorolone.
    Physiological genomics, 2018, 09-01, Volume: 50, Issue:9

    Topics: Animals; Base Sequence; Chronic Disease; Disease Models, Animal; Gene Expression Regulation; Inflamm

2018
Muscle miRNAome shows suppression of chronic inflammatory miRNAs with both prednisone and vamorolone.
    Physiological genomics, 2018, 09-01, Volume: 50, Issue:9

    Topics: Animals; Base Sequence; Chronic Disease; Disease Models, Animal; Gene Expression Regulation; Inflamm

2018
Muscle miRNAome shows suppression of chronic inflammatory miRNAs with both prednisone and vamorolone.
    Physiological genomics, 2018, 09-01, Volume: 50, Issue:9

    Topics: Animals; Base Sequence; Chronic Disease; Disease Models, Animal; Gene Expression Regulation; Inflamm

2018
Effects of panax notoginseng saponin on the pathological ultrastructure and serum IL-6 and IL-8 in pulmonary fibrosis in rabbits.
    Journal of cellular biochemistry, 2018, Volume: 119, Issue:10

    Topics: Analysis of Variance; Animals; Anti-Inflammatory Agents; Aspartate Aminotransferases; Creatine Kinas

2018
Bone-targeting liposome formulation of Salvianic acid A accelerates the healing of delayed fracture Union in Mice.
    Nanomedicine : nanotechnology, biology, and medicine, 2018, Volume: 14, Issue:7

    Topics: Animals; Anti-Inflammatory Agents; Caffeic Acids; Cholesterol; Disease Models, Animal; Drug Compound

2018
Glucocorticoid-induced delayed fracture healing and impaired bone biomechanical properties in mice.
    Clinical interventions in aging, 2018, Volume: 13

    Topics: Animals; Biomechanical Phenomena; Bone Remodeling; Bony Callus; Disease Models, Animal; Female; Femo

2018
Sanggenon C Stimulates Osteoblastic Proliferation and Differentiation, Inhibits Osteoclastic Resorption, and Ameliorates Prednisone-Induced Osteoporosis in Zebrafish Model.
    Molecules (Basel, Switzerland), 2018, Sep-13, Volume: 23, Issue:9

    Topics: Alkaline Phosphatase; Animals; Benzofurans; Cell Differentiation; Cell Line; Cell Proliferation; Chr

2018
How dogs are teaching researchers new tricks for treating cancer.
    Nature, 2018, Volume: 563, Issue:7731

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Cancer Vaccines; Clinical Trials, Veterinar

2018
IL-17F, rather than IL-17A, underlies airway inflammation in a steroid-insensitive toluene diisocyanate-induced asthma model.
    The European respiratory journal, 2019, Volume: 53, Issue:4

    Topics: Animals; Asthma; Bronchodilator Agents; Disease Models, Animal; Drug Resistance; Fluticasone; Glucoc

2019
MIDD0301 - A first-in-class anti-inflammatory asthma drug targets GABA
    Basic & clinical pharmacology & toxicology, 2019, Volume: 125, Issue:1

    Topics: Adjuvants, Immunologic; Administration, Oral; Animals; Anti-Inflammatory Agents; Asthma; Azepines; D

2019
Limited preventive effect of prednisone on neuropsychiatric symptoms in murine systemic lupus erythematosus.
    Inflammopharmacology, 2019, Volume: 27, Issue:3

    Topics: Animals; Brain; Cardiolipins; Depression; Disease Models, Animal; Female; Glucocorticoids; Lupus Vas

2019
Levels of α7 integrin and laminin-α2 are increased following prednisone treatment in the mdx mouse and GRMD dog models of Duchenne muscular dystrophy.
    Disease models & mechanisms, 2013, Volume: 6, Issue:5

    Topics: Animals; Antigens, CD; Disease Models, Animal; Dogs; Gene Expression Regulation; Humans; Integrin al

2013
Efficacy profiles for different concentrations of Lactobacillus acidophilus in experimental colitis.
    World journal of gastroenterology, 2013, Aug-28, Volume: 19, Issue:32

    Topics: Animals; Anti-Inflammatory Agents; Body Weight; Colitis; Colon; Dextran Sulfate; Disease Models, Ani

2013
Development of a mouse model mimicking key aspects of a viral asthma exacerbation.
    Clinical science (London, England : 1979), 2014, Volume: 126, Issue:8

    Topics: Animals; Asthma; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; CD4-Positive T-Lymphocytes

2014
Glucocorticoid-induced osteoporosis in growing rats.
    Calcified tissue international, 2014, Volume: 95, Issue:4

    Topics: Acetates; Animals; Biomarkers; Biomechanical Phenomena; Body Weight; Bone Resorption; Densitometry;

2014
Chronic Dosing with Membrane Sealant Poloxamer 188 NF Improves Respiratory Dysfunction in Dystrophic Mdx and Mdx/Utrophin-/- Mice.
    PloS one, 2015, Volume: 10, Issue:8

    Topics: Animals; Anti-Inflammatory Agents; Diaphragm; Disease Models, Animal; Dose-Response Relationship, Dr

2015
Effects of Tripterygium wilfordii glycosides on regulatory T cells and Th17 in an IgA nephropathy rat model.
    Genetics and molecular research : GMR, 2015, Nov-23, Volume: 14, Issue:4

    Topics: Animals; Disease Models, Animal; Glomerulonephritis, IGA; Glycosides; Humans; Prednisone; Rats; T-Ly

2015
Effectiveness and mode of action of a combination therapy for heterotopic ossification with a retinoid agonist and an anti-inflammatory agent.
    Bone, 2016, Volume: 90

    Topics: Animals; Anti-Inflammatory Agents; Body Weight; Cartilage; Cell Movement; Dexamethasone; Disease Mod

2016
Substrain-specific differences in bone parameters, alpha-2-macroglobulin circulating levels, and osteonecrosis incidence in a rat model.
    Journal of orthopaedic research : official publication of the Orthopaedic Research Society, 2017, Volume: 35, Issue:6

    Topics: alpha-Macroglobulins; Animals; Blood Glucose; Body Weight; Disease Models, Animal; Femur Head; Femur

2017
Single-agent cytarabine is insufficient for the treatment of human mantle cell lymphoma in mouse xenograft model.
    Neoplasma, 2016, Volume: 63, Issue:5

    Topics: Animals; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Cell Line,

2016
Ureaplasma urealyticum Causes Hyperammonemia in an Experimental Immunocompromised Murine Model.
    PloS one, 2016, Volume: 11, Issue:8

    Topics: Ammonia; Animals; Disease Models, Animal; Hyperammonemia; Immunocompromised Host; Immunosuppressive

2016
Effects and mechanisms of pirfenidone, prednisone and acetylcysteine on pulmonary fibrosis in rat idiopathic pulmonary fibrosis models.
    Pharmaceutical biology, 2017, Volume: 55, Issue:1

    Topics: Acetylcysteine; Animals; Bleomycin; Blotting, Western; Caveolin 1; Cytoprotection; Disease Models, A

2017
Biomechanical analysis of combined treatment of high calcium and bisphosphonate in tibia of steroid-treated growing-phase rats.
    Dental materials journal, 2008, Volume: 27, Issue:5

    Topics: Absorptiometry, Photon; Animals; Biomechanical Phenomena; Bone Density; Bone Density Conservation Ag

2008
Effects of the macrolide drug tylosin on chronic diarrhea in rhesus macaques (Macaca mulatta).
    Comparative medicine, 2008, Volume: 58, Issue:1

    Topics: Animals; Anti-Bacterial Agents; C-Reactive Protein; Chronic Disease; Colonoscopy; Cytokines; Diarrhe

2008
Functional and molecular effects of arginine butyrate and prednisone on muscle and heart in the mdx mouse model of Duchenne Muscular Dystrophy.
    PloS one, 2010, Jun-21, Volume: 5, Issue:6

    Topics: Animals; Arginine; Behavior, Animal; Butyrates; Disease Models, Animal; Drug Therapy, Combination; F

2010
Combinatorial treatments enhance recovery following facial nerve crush.
    The Laryngoscope, 2010, Volume: 120, Issue:8

    Topics: Animals; Combined Modality Therapy; Disease Models, Animal; Electric Stimulation Therapy; Facial Ner

2010
Viewing FOP through rosi-colored glasses.
    Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 2010, Volume: 25, Issue:11

    Topics: Animals; Disease Models, Animal; Female; Humans; Middle Aged; Myositis Ossificans; Prednisone; Rosig

2010
Steroid treatment alters adhesion molecule and chemokine expression in experimental acute graft-vs.-host disease of the intestinal tract.
    Experimental hematology, 2011, Volume: 39, Issue:2

    Topics: Animals; Bone Marrow Transplantation; Cell Adhesion Molecules; Chemokines; Cytokines; Disease Models

2011
Effect of artemisinin combined with glucocorticoid on the expressions of glucocorticoid receptor α mRNA, glucocorticoid receptor β mRNA and P300/CBP protein in lupus nephritis mice.
    Chinese journal of integrative medicine, 2011, Volume: 17, Issue:4

    Topics: Animals; Artemisinins; Base Sequence; Disease Models, Animal; DNA Primers; Electrophoresis, Agar Gel

2011
A rat model of early stage osteonecrosis induced by glucocorticoids.
    Journal of orthopaedic surgery and research, 2011, Dec-21, Volume: 6

    Topics: Animals; Apoptosis; Disease Models, Animal; Drug Implants; Female; Femur Head Necrosis; Genetic Pred

2011
Establishing Rps6 hemizygous mice as a model for studying how ribosomal protein haploinsufficiency impairs erythropoiesis.
    Experimental hematology, 2012, Volume: 40, Issue:4

    Topics: Agranulocytosis; Alleles; Anemia, Diamond-Blackfan; Anemia, Macrocytic; Animals; Chromosome Deletion

2012
Proteomic analysis indicates altered expression of plasma proteins in a rat nephropathy model.
    Clinical and experimental nephrology, 2013, Volume: 17, Issue:1

    Topics: Animals; Biomarkers; Blood Proteins; Databases, Protein; Disease Models, Animal; Doxorubicin; Glucoc

2013
Biochemistry: A radical treatment.
    Nature, 2012, Sep-27, Volume: 489, Issue:7417

    Topics: Animals; Antioxidants; Clinical Trials as Topic; Disease Models, Animal; Free Radicals; Humans; Isot

2012
[Effect of artemisinin on the expressions of GRalpha mRNA, GRbeta mRNA and P300/CBP protein in lupus nephritis mice].
    Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials, 2012, Volume: 35, Issue:4

    Topics: Animals; Artemisia annua; Artemisinins; Disease Models, Animal; Female; Leukocytes, Mononuclear; Lup

2012
A comparison of effects of ABVD and ChlVPP chemotherapeutic protocols for Hodgkin's disease on rats' epididiymal and testicular tissues.
    Pakistan journal of biological sciences : PJBS, 2010, Sep-15, Volume: 13, Issue:18

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Chlorambucil; Dacarbazine; Disea

2010
Effects of prednisone and ibuprofen on radio frequency volume tissue reduction in a rabbit model.
    The Annals of otology, rhinology, and laryngology, 2002, Volume: 111, Issue:11

    Topics: Animals; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Data Interpretation, Sta

2002
Prednisone reduces muscle degeneration in dystrophin-deficient Caenorhabditis elegans.
    Neuromuscular disorders : NMD, 2004, Volume: 14, Issue:6

    Topics: Animals; Anti-Inflammatory Agents; Caenorhabditis elegans; Caenorhabditis elegans Proteins; Disease

2004
Prednisone in dystrophin-deficient Caernorabditis elegans.
    Neuromuscular disorders : NMD, 2004, Volume: 14, Issue:10

    Topics: Animals; Anti-Inflammatory Agents; Caenorhabditis elegans; Disease Models, Animal; Dystrophin; Muscu

2004
Bone quality in swine composite tissue allografts: effects of combination immunotherapy.
    Transplantation, 2005, Aug-27, Volume: 80, Issue:4

    Topics: Animals; Bone Density; Disease Models, Animal; Drug Therapy, Combination; Forelimb; Glucocorticoids;

2005
Therapeutic effect of Chinese medicine formula DSQRL on experimental pulmonary fibrosis.
    Journal of ethnopharmacology, 2007, Feb-12, Volume: 109, Issue:3

    Topics: Animals; Bronchoalveolar Lavage Fluid; Carbon Tetrachloride; Collagen; Disease Models, Animal; Drugs

2007
Capillaria hepatica in rats: focal parasitic hepatic lesions and septal fibrosis run independent courses.
    Memorias do Instituto Oswaldo Cruz, 2006, Volume: 101, Issue:8

    Topics: Animals; Antibodies, Helminth; Antigens, Helminth; Capillaria; Chronic Disease; Disease Models, Anim

2006
[An experimental study on osteocyte apoptosis in steroid-induced early osteonecrosis of femoral head].
    Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery, 2007, Volume: 21, Issue:3

    Topics: Animals; Apoptosis; Disease Models, Animal; Female; Femur Head; Femur Head Necrosis; In Situ Nick-En

2007
Effects of oral prednisone after stenting in a rabbit model of established atherosclerosis.
    Journal of the American College of Cardiology, 2007, Jul-10, Volume: 50, Issue:2

    Topics: Administration, Oral; Animals; Anti-Inflammatory Agents; Aorta; Atherosclerosis; Cell Proliferation;

2007
Prednisone prevents inducible atrial flutter in the canine sterile pericarditis model.
    Journal of cardiovascular electrophysiology, 2008, Volume: 19, Issue:1

    Topics: Animals; Anti-Inflammatory Agents; Atrial Flutter; Disease Models, Animal; Dogs; Dose-Response Relat

2008
Preventing atrial flutter by preventing inflammation.
    Journal of cardiovascular electrophysiology, 2008, Volume: 19, Issue:1

    Topics: Animals; Anti-Inflammatory Agents; Atrial Flutter; Disease Models, Animal; Dogs; Dose-Response Relat

2008
In vitro and in vivo pharmacological profile of UFP-512, a novel selective delta-opioid receptor agonist; correlations between desensitization and tolerance.
    British journal of pharmacology, 2007, Volume: 152, Issue:8

    Topics: Animals; Antidepressive Agents; Antineoplastic Combined Chemotherapy Protocols; Benzimidazoles; Bind

2007
Experimental disseminated strongyloidiasis in Erythrocebus patas. I. Pathology.
    The American journal of tropical medicine and hygiene, 1984, Volume: 33, Issue:3

    Topics: Animals; Basophils; Cercopithecidae; Disease Models, Animal; Eosinophilia; Erythrocebus patas; Immun

1984
Experimental disseminated strongyloidiasis in Erythrocebus patas. II. Immunology.
    The American journal of tropical medicine and hygiene, 1984, Volume: 33, Issue:3

    Topics: Animals; Cercopithecidae; Disease Models, Animal; Erythrocebus patas; Immunoglobulin E; Immunoglobul

1984
Interleukin-6 activity in dogs with juvenile polyarteritis syndrome: effect of corticosteroids.
    Clinical immunology and immunopathology, 1995, Volume: 77, Issue:1

    Topics: Animals; Anti-Inflammatory Agents; Cytokines; Disease Models, Animal; Dog Diseases; Dogs; Fever; Imm

1995
Concanavalin A-induced posterior subcapsular cataract: a new model of cataractogenesis.
    Investigative ophthalmology & visual science, 1993, Volume: 34, Issue:13

    Topics: Administration, Topical; Animals; Anterior Chamber; Cataract; Concanavalin A; Disease Models, Animal

1993
Nephrotic mice (ICGN strain): a model of diffuse mesangial sclerosis in infantile nephrotic syndrome.
    American journal of nephrology, 1999, Volume: 19, Issue:1

    Topics: Albuminuria; Animals; Anti-Inflammatory Agents; Disease Models, Animal; Glomerular Mesangium; Immuno

1999
Clinical outcome of a protocol to produce immunosuppression in rhesus monkeys (Macaca mulatta): application to infectious disease and gene therapy studies.
    Journal of medical primatology, 1999, Volume: 28, Issue:6

    Topics: Animals; Cyclophosphamide; Disease Models, Animal; Dose-Response Relationship, Drug; Genetic Therapy

1999
Aerogenous infection of microbiologically defined minipigs with Streptococcus suis serotype 2. A new model.
    APMIS : acta pathologica, microbiologica, et immunologica Scandinavica, 2001, Volume: 109, Issue:6

    Topics: Animals; Antigens, Bacterial; Bacteremia; Disease Models, Animal; Female; Humans; Immunohistochemist

2001
The significance of cutaneous immunoglobulin deposits in lupus erythematosus and NZB/NZW F1 hybrid mice.
    The Journal of investigative dermatology, 1975, Volume: 65, Issue:1

    Topics: Animals; Antibodies; Autoantigens; Autoimmune Diseases; Blood Proteins; Cell Nucleus; Complement Sys

1975
[Comparison of the effects of sodium fluoride and calcidiol on the remodeling of the endosteal surface of the rib cortex in dogs after administration of prednisone].
    Polskie Archiwum Medycyny Wewnetrznej, 1992, Volume: 87, Issue:2

    Topics: Animals; Bone Remodeling; Calcifediol; Disease Models, Animal; Dogs; Drug Synergism; Osteoporosis; P

1992
[Effects of D-penicillamine and encorton on the fibrotic processes in experimental liver cirrhosis in rats].
    Patologia polska, 1990, Volume: 41, Issue:1-2

    Topics: Animals; Carbon Tetrachloride Poisoning; Collagen; Disease Models, Animal; Dose-Response Relationshi

1990
Suppression of the immune reaction in multiple sclerosis might be achieved by intravenous injections of myelin basic protein, concomitant with the administration of an immunosuppressant and a corticosteroid.
    Medical hypotheses, 1988, Volume: 25, Issue:4

    Topics: Autoimmune Diseases; Disease Models, Animal; Encephalomyelitis, Autoimmune, Experimental; Humans; Im

1988
Suppression of the immune reaction in multiple sclerosis might be achieved by intravenous injections of myelin basic protein, concomitant with the administration of an immunosuppressant and a corticosteroid.
    Medical hypotheses, 1988, Volume: 26, Issue:2

    Topics: Animals; Autoimmune Diseases; Azathioprine; Disease Models, Animal; Drug Therapy, Combination; Encep

1988
Therapy of chronic graft-v-host disease in a rat model.
    Blood, 1989, Volume: 74, Issue:1

    Topics: Animals; Azathioprine; Cyclosporins; Disease Models, Animal; Drug Synergism; Graft vs Host Disease;

1989
Role of synovial membrane inflammation in cartilage matrix breakdown in the Pond-Nuki dog model of osteoarthritis.
    Arthritis and rheumatism, 1985, Volume: 28, Issue:5

    Topics: Animals; Cartilage, Articular; Disease Models, Animal; DNA; Dogs; Microbial Collagenase; Osteoarthri

1985
A two-stage therapeutic design in the spontaneous AKR lymphoma system.
    Cancer research, 1972, Volume: 32, Issue:6

    Topics: Amides; Animals; Antineoplastic Agents; Azacitidine; Cyclic P-Oxides; Cyclophosphamide; Cytarabine;

1972
Modification of 1-tyrosine-induced keratopathy by adrenal corticosteroids.
    Investigative ophthalmology, 1974, Volume: 13, Issue:1

    Topics: Animals; Betamethasone; Corneal Opacity; Dexamethasone; Dietary Proteins; Disease Models, Animal; Fe

1974
Recurrent cutaneous herpes simplex in hairless mice.
    Infection and immunity, 1974, Volume: 10, Issue:3

    Topics: Animals; Culture Techniques; Cytopathogenic Effect, Viral; Disease Models, Animal; Hair; Herpes Simp

1974
Combination chemotherapy for spontaneous AKR lymphoma.
    Cancer chemotherapy reports. Part 2, 1974, Volume: 4, Issue:1

    Topics: Animals; Antineoplastic Agents; Biological Assay; Carmustine; Cyclohexanes; Cyclophosphamide; Cytara

1974
Comparative chemotherapy of AKR lymphoma and human hematological neoplasia.
    Cancer research, 1974, Volume: 34, Issue:1

    Topics: Animals; Antineoplastic Agents; Biological Assay; Carmustine; Cyclohexanes; Cyclophosphamide; Cytara

1974
The effect of corticosteroids on the retinal cryoadhesion.
    Canadian journal of ophthalmology. Journal canadien d'ophtalmologie, 1973, Volume: 8, Issue:4

    Topics: Adhesiveness; Animals; Biomedical Engineering; Conjunctiva; Cryosurgery; Disease Models, Animal; Inf

1973
Clinical and pathologic study of canine lymphoma: clinical staging, cell classification, and therapy.
    Journal of the National Cancer Institute, 1973, Volume: 51, Issue:2

    Topics: Animals; Antineoplastic Agents; Bacterial Infections; Cyclophosphamide; Disease Models, Animal; Dog

1973
Corticosteroid therapy in Felty's syndrome and its effect on hypersplenic rats.
    British journal of haematology, 1974, Volume: 26, Issue:2

    Topics: Aged; Anemia; Animals; Body Weight; Chromium Radioisotopes; Disease Models, Animal; Felty Syndrome;

1974
Goodpasture's syndrome: recovery from severe pulmonary hemorrhage after bilateral nephrectomy.
    Annals of internal medicine, 1971, Volume: 75, Issue:2

    Topics: Adult; Anti-Glomerular Basement Membrane Disease; Autoantibodies; Azathioprine; Complement System Pr

1971
Response of "acute phase" globulins in different models of inflammation in rats.
    Life sciences. Pt. 1: Physiology and pharmacology, 1971, May-01, Volume: 10, Issue:9

    Topics: Acute Disease; Adjuvants, Immunologic; Animals; Arthritis; Aspirin; Disease Models, Animal; Granulom

1971
Chemical prevention of experimental allergic encephalomyelitis in rats: a quantitative evaluation of steroids and various non-steroid drugs.
    Archives internationales de pharmacodynamie et de therapie, 1971, Volume: 193, Issue:2

    Topics: Aminopyrine; Animals; Anti-Inflammatory Agents; Bis-Trimethylammonium Compounds; Cortisone; Cyclopho

1971
The treatment of acute lymphocytic leukemia.
    Journal of chronic diseases, 1970, Volume: 22, Issue:10

    Topics: Animals; Antineoplastic Agents; Asparaginase; Blood Platelets; Bone Marrow Cells; Cyclophosphamide;

1970
The effect of cortisone on the development of Schistosoma haematobium in mice.
    Bulletin of endemic diseases, 1969, Volume: 11, Issue:1

    Topics: Animals; Disease Models, Animal; Mice; Mice, Inbred Strains; Prednisone; Schistosoma haematobium; Sc

1969
Cryotherapy of stromal herpes simplex keratitis in rabbits.
    American journal of ophthalmology, 1971, Jul-30, Volume: 72, Issue:1

    Topics: Animals; Cataract; Cornea; Cryosurgery; Disease Models, Animal; Keratitis, Dendritic; Prednisone; Pr

1971