prednisone has been researched along with Depressive Disorder in 21 studies
Prednisone: A synthetic anti-inflammatory glucocorticoid derived from CORTISONE. It is biologically inert and converted to PREDNISOLONE in the liver.
prednisone : A synthetic glucocorticoid drug that is particularly effective as an immunosuppressant, and affects virtually all of the immune system. Prednisone is a prodrug that is converted by the liver into prednisolone (a beta-hydroxy group instead of the oxo group at position 11), which is the active drug and also a steroid.
Depressive Disorder: An affective disorder manifested by either a dysphoric mood or loss of interest or pleasure in usual activities. The mood disturbance is prominent and relatively persistent.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Sixty-seven adults with severe prednisone-dependent asthma, 47 with severe non-prednisone dependent and 73 patients with mild-moderate asthma completed the HADS depression and anxiety subscale and the NEO-FFI for personality traits." | 7.80 | Anxiety, depression and personality traits in severe, prednisone-dependent asthma. ( Amelink, M; Bel, EH; Hashimoto, S; Pasma, HR; Spinhoven, P; Sterk, PJ; ten Brinke, A, 2014) |
| "Thirty outpatients given systemic corticosteroid therapy for asthma were randomized to either levetiracetam (1500 mg/day) or placebo given concurrently with the corticosteroids." | 5.12 | Impact of levetiracetam on mood and cognition during prednisone therapy. ( Bret, ME; Brown, ES; Frol, AB; Khan, DA; Larkin, GL, 2007) |
| "Sixty-seven adults with severe prednisone-dependent asthma, 47 with severe non-prednisone dependent and 73 patients with mild-moderate asthma completed the HADS depression and anxiety subscale and the NEO-FFI for personality traits." | 3.80 | Anxiety, depression and personality traits in severe, prednisone-dependent asthma. ( Amelink, M; Bel, EH; Hashimoto, S; Pasma, HR; Spinhoven, P; Sterk, PJ; ten Brinke, A, 2014) |
| " We previously reported greater depressive symptom severity, poorer memory and smaller hippocampal volumes in patients with asthma or rheumatic diseases receiving long-term prednisone therapy than in controls." | 3.74 | Effects of chronic prednisone therapy on mood and memory. ( Brown, ES; Frol, AB; Johnson, B; Vera, E; Woolston, DJ, 2007) |
| " Olanzapine dosing was flexible beginning at 2." | 2.71 | An open-label trial of olanzapine for corticosteroid-induced mood symptoms. ( Brown, ES; Carmody, TJ; Chamberlain, W; Dhanani, N; Paranjpe, P; Sargeant, M, 2004) |
| "Nortriptyline treatment was accompanied by marked improvements in anxiety, certain respiratory symptoms, overall physical comfort, and day-to-day function; placebo effects were negligible." | 2.67 | Improvement in mood, physical symptoms, and function with nortriptyline for depression in patients with chronic obstructive pulmonary disease. ( Borson, S; Deffebach, M; Gayle, T; Lakshminarayan, S; McDonald, GJ; VanTuinen, C, 1992) |
| "The pattern of use strongly suggested drug dependence; secondary Cushing's syndrome was noted." | 1.27 | Corticosteroid abuse--an unusual manifestation of drug dependence. ( Flavin, DK; Fredrickson, PA; Merritt, TC; Richardson, JW, 1983) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (23.81) | 18.7374 |
| 1990's | 6 (28.57) | 18.2507 |
| 2000's | 6 (28.57) | 29.6817 |
| 2010's | 4 (19.05) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Amelink, M | 1 |
| Hashimoto, S | 1 |
| Spinhoven, P | 1 |
| Pasma, HR | 1 |
| Sterk, PJ | 1 |
| Bel, EH | 1 |
| ten Brinke, A | 1 |
| Ramos-Zúñiga, R | 1 |
| Pérez-Gómez, HR | 1 |
| Gaytán-Martínez, LA | 1 |
| Vega-Ruiz, B | 1 |
| Soto-Rodríguez, S | 1 |
| Rochín-Mozqueda, A | 1 |
| Veltman, EM | 1 |
| Rhebergen, D | 1 |
| van Exel, E | 1 |
| Stek, ML | 1 |
| Boccardi, V | 1 |
| Croce, MF | 1 |
| Ruggiero, C | 1 |
| Aisa, G | 1 |
| Tosti, A | 1 |
| Mecocci, P | 1 |
| Ahmed, R | 1 |
| Eagleton, C | 1 |
| RICHARDS, AG | 1 |
| Brown, ES | 4 |
| Chamberlain, W | 1 |
| Dhanani, N | 1 |
| Paranjpe, P | 1 |
| Carmody, TJ | 2 |
| Sargeant, M | 1 |
| Vera, E | 1 |
| Frol, AB | 2 |
| Woolston, DJ | 1 |
| Johnson, B | 1 |
| Khan, DA | 2 |
| Larkin, GL | 1 |
| Bret, ME | 1 |
| Flavin, DK | 1 |
| Fredrickson, PA | 1 |
| Richardson, JW | 1 |
| Merritt, TC | 1 |
| Uva, JL | 1 |
| Terao, T | 1 |
| Yoshimura, R | 1 |
| Shiratuchi, T | 1 |
| Abe, K | 1 |
| Abouesh, A | 1 |
| Hobbs, WR | 1 |
| Lineberry, TW | 1 |
| Peters, GE | 1 |
| Bostwick, JM | 1 |
| Suppes, T | 1 |
| Borson, S | 1 |
| McDonald, GJ | 1 |
| Gayle, T | 1 |
| Deffebach, M | 1 |
| Lakshminarayan, S | 1 |
| VanTuinen, C | 1 |
| Hassanyeh, F | 1 |
| Murray, RB | 1 |
| Rodgers, H | 1 |
| Wolkowitz, OM | 1 |
| Reus, VI | 1 |
| Weingartner, H | 1 |
| Thompson, K | 1 |
| Breier, A | 1 |
| Doran, A | 1 |
| Rubinow, D | 1 |
| Pickar, D | 1 |
| Gift, AG | 1 |
| Wood, RM | 1 |
| Cahill, CA | 1 |
| Joffe, RT | 1 |
| Denicoff, KD | 1 |
| Rubinow, DR | 1 |
| Tsokos, G | 1 |
| Balow, JE | 1 |
| Pillemer, SE | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Steroid-induced Mood Changes in Patients With Inflammatory Bowel Disease[NCT01981889] | Phase 4 | 53 participants (Actual) | Interventional | 2013-10-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
3 trials available for prednisone and Depressive Disorder
| Article | Year |
|---|---|
An open-label trial of olanzapine for corticosteroid-induced mood symptoms.
Topics: Adrenal Cortex Hormones; Adult; Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Depressive | 2004 |
Impact of levetiracetam on mood and cognition during prednisone therapy.
Topics: Adolescent; Adult; Affect; Aged; Anti-Inflammatory Agents; Antidepressive Agents; Asthma; Cognition; | 2007 |
Improvement in mood, physical symptoms, and function with nortriptyline for depression in patients with chronic obstructive pulmonary disease.
Topics: Activities of Daily Living; Affect; Attitude to Health; Chronic Disease; Depressive Disorder; Dyspne | 1992 |
18 other studies available for prednisone and Depressive Disorder
| Article | Year |
|---|---|
Anxiety, depression and personality traits in severe, prednisone-dependent asthma.
Topics: Adolescent; Adult; Aged; Anxiety Disorders; Asthma; Cross-Sectional Studies; Depressive Disorder; Fe | 2014 |
[Temporal lobe epilepsy and active neurocysticercosis: two representative case reports].
Topics: Albendazole; Anomia; Anthelmintics; Anticonvulsants; Antipsychotic Agents; Carbamazepine; Citalopram | 2015 |
[Hashimoto encephalitis and depression].
Topics: Aged; Brain Diseases; Depressive Disorder; Electroconvulsive Therapy; Encephalitis; Female; Hashimot | 2015 |
Subjective memory complaints and depression as clinical symptoms of disseminated nocardiosis by Nocardia abscessus.
Topics: Aged; Arthritis, Rheumatoid; Bacteremia; Depressive Disorder; Female; Follow-Up Studies; Humans; Inf | 2016 |
Toxic epidermal necrolysis after paroxetine treatment.
Topics: Aged, 80 and over; Anti-Inflammatory Agents; Antidepressive Agents, Second-Generation; Biopsy; Depre | 2008 |
MALATHION POISONING SUCCESSFULLY TREATED WITH LARGE DOSES OF ATROPINE.
Topics: Anti-Bacterial Agents; Atropine; Chloramphenicol; Cholinesterases; Depression; Depressive Disorder; | 1964 |
Effects of chronic prednisone therapy on mood and memory.
Topics: Adult; Affect; Asthma; Atrophy; Bipolar Disorder; Depressive Disorder; Female; Follow-Up Studies; Hi | 2007 |
Corticosteroid abuse--an unusual manifestation of drug dependence.
Topics: Adult; Cushing Syndrome; Depressive Disorder; Humans; Male; Prednisone; Substance-Related Disorders | 1983 |
Corticosteroid-induced suicide attempt.
Topics: Depressive Disorder; Female; Glucocorticoids; Humans; Middle Aged; Prednisone; Suicide, Attempted | 1996 |
Effects of lithium on steroid-induced depression.
Topics: Adult; Aged; Anti-Inflammatory Agents; Depressive Disorder; Female; Humans; Lithium; Lupus Erythemat | 1997 |
Clarithromycin-induced mania.
Topics: Bipolar Disorder; Clarithromycin; Depressive Disorder; Female; Haloperidol; Humans; Lithium; Middle | 1998 |
Bupropion-induced erythema multiforme.
Topics: Administration, Oral; Adult; Aftercare; Anti-Inflammatory Agents; Antidepressive Agents, Second-Gene | 2001 |
Mood changes during prednisone bursts in outpatients with asthma.
Topics: Adolescent; Adult; Affect; Asthma; Bipolar Disorder; Depressive Disorder; Dose-Response Relationship | 2002 |
Adrenocortical suppression presenting with agitated depression, morbid jealousy, and a dementia-like state.
Topics: Aged; Akathisia, Drug-Induced; Asthma; Dementia; Depressive Disorder; Female; Humans; Jealousy; Neur | 1991 |
Cognitive effects of corticosteroids.
Topics: Adrenal Cortex Hormones; Arousal; Cognition; Cognition Disorders; Depressive Disorder; Dexamethasone | 1990 |
Depression, somatization and steroid use in chronic obstructive pulmonary disease.
Topics: Aged; Depressive Disorder; Humans; Lung Diseases, Obstructive; Male; Middle Aged; Personality Invent | 1989 |
Mood effects of alternate-day corticosteroid therapy in patients with systemic lupus erythematosus.
Topics: Adult; Anxiety Disorders; Cognition Disorders; Depressive Disorder; Drug Administration Schedule; Fe | 1988 |
An association between norepinephrine-to-epinephrine ratio and suicidal ideation in depression.
Topics: Depressive Disorder; Enzyme Induction; Epinephrine; Humans; Kidney Transplantation; Norepinephrine; | 1986 |