Page last updated: 2024-11-07

prednisone and Debility

prednisone has been researched along with Debility in 10 studies

Prednisone: A synthetic anti-inflammatory glucocorticoid derived from CORTISONE. It is biologically inert and converted to PREDNISOLONE in the liver.
prednisone : A synthetic glucocorticoid drug that is particularly effective as an immunosuppressant, and affects virtually all of the immune system. Prednisone is a prodrug that is converted by the liver into prednisolone (a beta-hydroxy group instead of the oxo group at position 11), which is the active drug and also a steroid.

Research Excerpts

ExcerptRelevanceReference
"The first application uses a classic textbook example on prednisone treatment and liver functioning among liver cirrhosis patients."3.96Estimating the number and length of episodes in disability using a Markov chain approach. ( Dudel, C; Myrskylä, M, 2020)
"Patients with multiple myeloma are generally older and vary in fitness levels, which may influence the clinical benefit of treatment."2.94A simplified frailty scale predicts outcomes in transplant-ineligible patients with newly diagnosed multiple myeloma treated in the FIRST (MM-020) trial. ( Attal, M; Belch, A; Boyle, E; Chen, WM; Costa, B; Dimopoulos, MA; Facon, T; Guo, S; Houck, V; Hulin, C; Kim, K; Leleu, X; Lorraine Chretien, M; Ludwig, H; Macro, M; Manier, S; Meuleman, N; Mohty, M; Moreau, P; Renwick, W; Rodriguez-Otero, P; Rose, C; Silvia Monzini, M; Sturniolo, M; Tempescul, A; Tinel, A; Yves Mary, J; Zamagni, E, 2020)
"Older age and higher frailty score were significantly associated with increased risk for serious infection."1.72Giant cell arteritis treatment patterns and rates of serious infections. ( Jin, Y; Kim, SC; Lee, H; Pethoe-Schramm, A; Tedeschi, SK; Vine, S; Yau, V, 2022)
"Frailty is a significant risk factor for poor outcomes among older patients with diffuse large B-cell lymphoma (DLBCL)."1.72Electronic FRAIL score as a predictor of treatment outcomes in older patients with diffuse large B-cell lymphoma. ( Chan, H; Disperati, P; Elinder-Camburn, A; Leitch, S; Merriman, E; Zhang, J, 2022)

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's2 (20.00)24.3611
2020's8 (80.00)2.80

Authors

AuthorsStudies
Tedeschi, SK1
Jin, Y1
Vine, S1
Lee, H1
Pethoe-Schramm, A1
Yau, V1
Kim, SC1
Zhang, J1
Disperati, P1
Elinder-Camburn, A1
Merriman, E1
Leitch, S1
Chan, H1
Ugarte-Gil, MF1
Dubey, J1
McGwin, G1
Reveille, JD1
Vilá, LM1
Alarcón, GS1
Yagi, Y1
Kanemasa, Y1
Sasaki, Y1
Goto, S1
Yamamura, Y1
Ishimine, K1
Hayashi, Y1
Mino, M1
Ohigashi, A1
Morita, Y1
Tamura, T1
Nakamura, S1
Okuya, T1
Shimoyama, T1
Facon, T1
Dimopoulos, MA1
Meuleman, N1
Belch, A1
Mohty, M1
Chen, WM1
Kim, K2
Zamagni, E1
Rodriguez-Otero, P1
Renwick, W1
Rose, C1
Tempescul, A1
Boyle, E1
Manier, S1
Attal, M1
Moreau, P1
Macro, M1
Leleu, X1
Lorraine Chretien, M1
Ludwig, H1
Guo, S1
Sturniolo, M1
Tinel, A1
Silvia Monzini, M1
Costa, B1
Houck, V1
Hulin, C1
Yves Mary, J1
Lee, HS1
Kim, SJ1
Lee, JJ1
Kim, I1
Kim, JS1
Eom, HS1
Yoon, DH1
Suh, C1
Shin, HJ1
Mun, YC1
Kim, MK1
Lim, SN1
Choi, CW1
Kang, HJ1
Yoon, SS1
Min, CK1
Dudel, C1
Myrskylä, M1
Cordoba, R1
Luminari, S1
Eyre, TA1
Beygi, S1
Sadashiv, S1
Reilly, JB1
Khan, C1
Lister, J1
Chaganti, S1
Illidge, T1
Barrington, S1
Mckay, P1
Linton, K1
Cwynarski, K1
McMillan, A1
Davies, A1
Stern, S1
Peggs, K1

Clinical Trials (4)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Multicenter, Phase II, National and Open-label Study to Evaluate Iberdomide-dexamethasone Alone or in Combination With Standard MM Treatment Regimens in Transplant Ineligible Newly Diagnosed Patients.[NCT05527340]Phase 2140 participants (Anticipated)Interventional2022-09-30Not yet recruiting
An Open Label, Multicenter, Phase 2, Pilot Study, Evaluating Early Treatment With Bispecific T-cell Redirectors (Teclistamab and Talquetamab) in the Frontline Therapy of Newly Diagnosed High-risk Multiple Myeloma[NCT05849610]Phase 230 participants (Anticipated)Interventional2023-11-30Recruiting
Isatuximab in Combination With Lenalidomide-Dexamethasone Compared to Lenalidomide-Dexamethasone in Elderly Patients (Aged ≥70 Years) With Newly Diagnosed Myeloma: a Randomized Phase II Study (SGZ-2019-12650)[NCT04891809]Phase 2198 participants (Anticipated)Interventional2021-10-20Recruiting
A Multicentre, Randomized Phase III Study of Thalidomide Maintenance Treatment in Patients With Diffuse Large B-cell Lymphoma[NCT03016000]Phase 3226 participants (Anticipated)Interventional2017-07-26Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

2 reviews available for prednisone and Debility

ArticleYear
The use of frailty assessments in treating older adults with aggressive lymphomas.
    British journal of haematology, 2021, Volume: 194, Issue:4

    Topics: Age Factors; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemo

2021
Frontline treatment of diffuse large B-cell lymphoma in elderly: a systematic review of clinical trials in post-rituximab era.
    Leukemia & lymphoma, 2018, Volume: 59, Issue:12

    Topics: Age Factors; Aged; Aged, 80 and over; Antibodies, Monoclonal, Murine-Derived; Antineoplastic Combine

2018

Trials

2 trials available for prednisone and Debility

ArticleYear
A simplified frailty scale predicts outcomes in transplant-ineligible patients with newly diagnosed multiple myeloma treated in the FIRST (MM-020) trial.
    Leukemia, 2020, Volume: 34, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Dexamethasone; Femal

2020
A simplified frailty scale predicts outcomes in transplant-ineligible patients with newly diagnosed multiple myeloma treated in the FIRST (MM-020) trial.
    Leukemia, 2020, Volume: 34, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Dexamethasone; Femal

2020
A simplified frailty scale predicts outcomes in transplant-ineligible patients with newly diagnosed multiple myeloma treated in the FIRST (MM-020) trial.
    Leukemia, 2020, Volume: 34, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Dexamethasone; Femal

2020
A simplified frailty scale predicts outcomes in transplant-ineligible patients with newly diagnosed multiple myeloma treated in the FIRST (MM-020) trial.
    Leukemia, 2020, Volume: 34, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Dexamethasone; Femal

2020
A simplified frailty scale predicts outcomes in transplant-ineligible patients with newly diagnosed multiple myeloma treated in the FIRST (MM-020) trial.
    Leukemia, 2020, Volume: 34, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Dexamethasone; Femal

2020
A simplified frailty scale predicts outcomes in transplant-ineligible patients with newly diagnosed multiple myeloma treated in the FIRST (MM-020) trial.
    Leukemia, 2020, Volume: 34, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Dexamethasone; Femal

2020
A simplified frailty scale predicts outcomes in transplant-ineligible patients with newly diagnosed multiple myeloma treated in the FIRST (MM-020) trial.
    Leukemia, 2020, Volume: 34, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Dexamethasone; Femal

2020
A simplified frailty scale predicts outcomes in transplant-ineligible patients with newly diagnosed multiple myeloma treated in the FIRST (MM-020) trial.
    Leukemia, 2020, Volume: 34, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Dexamethasone; Femal

2020
A simplified frailty scale predicts outcomes in transplant-ineligible patients with newly diagnosed multiple myeloma treated in the FIRST (MM-020) trial.
    Leukemia, 2020, Volume: 34, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Dexamethasone; Femal

2020
Pomalidomide, cyclophosphamide, and dexamethasone for elderly patients with relapsed and refractory multiple myeloma: A study of the Korean Multiple Myeloma Working Party (KMMWP-164 study).
    American journal of hematology, 2020, Volume: 95, Issue:4

    Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Bortezomib; Cyclophosphamid

2020

Other Studies

6 other studies available for prednisone and Debility

ArticleYear
Giant cell arteritis treatment patterns and rates of serious infections.
    Clinical and experimental rheumatology, 2022, Volume: 40, Issue:4

    Topics: Aged; Anti-Bacterial Agents; Female; Frailty; Giant Cell Arteritis; Humans; Immunosuppressive Agents

2022
Electronic FRAIL score as a predictor of treatment outcomes in older patients with diffuse large B-cell lymphoma.
    Journal of geriatric oncology, 2022, Volume: 13, Issue:4

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Doxorubicin; Electronics; Fr

2022
Association of Systemic Lupus International Collaborating Clinics Frailty Index With Damage in Systemic Lupus Erythematosus Patients: Results From a Multiethnic, Multicenter US Cohort of Patients With Lupus.
    Arthritis care & research, 2023, Volume: 75, Issue:3

    Topics: Adult; Ethnicity; Female; Frailty; Humans; Lupus Erythematosus, Systemic; Male; Middle Aged; Prednis

2023
Utility of the frailty score for predicting prognosis and individualizing treatment intensity in elderly patients with diffuse large B cell lymphoma.
    Annals of hematology, 2023, Volume: 102, Issue:6

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Doxorubicin; Frailty; Humans

2023
Estimating the number and length of episodes in disability using a Markov chain approach.
    Population health metrics, 2020, 07-29, Volume: 18, Issue:1

    Topics: Activities of Daily Living; Algorithms; Disabled Persons; Frailty; Humans; Life Expectancy; Liver Ci

2020
Guidelines for the management of diffuse large B-cell lymphoma.
    British journal of haematology, 2016, Volume: 174, Issue:1

    Topics: Antibodies, Monoclonal, Murine-Derived; Antineoplastic Combined Chemotherapy Protocols; Cyclophospha

2016