prednisone has been researched along with Conus Medullaris Syndrome in 38 studies
Prednisone: A synthetic anti-inflammatory glucocorticoid derived from CORTISONE. It is biologically inert and converted to PREDNISOLONE in the liver.
prednisone : A synthetic glucocorticoid drug that is particularly effective as an immunosuppressant, and affects virtually all of the immune system. Prednisone is a prodrug that is converted by the liver into prednisolone (a beta-hydroxy group instead of the oxo group at position 11), which is the active drug and also a steroid.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Epidural lipomatosis is a condition in which excess adipose tissue is deposited circumferentially about the spinal cord in the epidural space." | 2.38 | Epidural lipomatosis in steroid-treated patients. ( Brown, FD; Erickson, RK; Fessler, RG; Johnson, DL; Kranzler, L; Reid, SA, 1992) |
| "Initial spinal cord compression (ISCC) in B-cell non-Hodgkin lymphoma (NHL) is rarely present at diagnosis." | 1.42 | Management and prognosis of 66 patients with B-cell non-Hodgkin lymphoma presenting with initial spinal cord compression: a French retrospective multicenter study. ( Amorim, S; Brice, P; Brière, J; Coiffier, B; de Kerviler, E; Dupuis, J; Filliatre, L; Fleury, I; Mazari, MA; Mounier, N; Thieblemont, C; Tilly, H, 2015) |
| "A 58-year-old Caucasian woman with multiple myeloma developed subacute vision loss bilaterally and was found to have plasma cells in her cerebrospinal fluid." | 1.37 | Central nervous system myelomatosis with optic neuropathy and intramedullary spinal cord compression responding to radiation therapy. ( Alsharif, M; Jenrette, JM; Riley, JM; Russo, JK; Shipp, A, 2011) |
| "The differential diagnosis of spinal cord compression in a patient who has had a transplant should include primary presentation of PTLD." | 1.35 | Extradural thoracic spinal cord compression: unusual initial presentation of post-transplant lymphoproliferative disorder. ( Bakker, NA; Coppes, MH; Slart, RH; van Dijk, JM; van Imhoff, GW; Verschuuren, EA, 2008) |
| "Dorsolateral spinal cord compression associated with articular process hypertrophy was the most common feature of cervical vertebral malformation-malarticulation in the seven Bernese mountain dogs evaluated." | 1.35 | Cervical vertebral malformation-malarticulation syndrome in the Bernese mountain dog: clinical and magnetic resonance imaging features. ( Diaz, J; Eagleson, JS; Kent, M; Levine, JM; Platt, SR; Schatzberg, SJ; Sharp, NJ, 2009) |
| "Neurosarcoidosis is a rare manifestation of sarcoidosis." | 1.33 | Cauda equina and conus medullaris syndrome in sarcoidosis. ( Hayat, GR; Kaiboriboon, K; Olsen, TJ, 2005) |
| "The histopathological study revealed a follicular lymphoma." | 1.33 | [Medullary compression revealing the presence of a follicular lymphoma: a case report]. ( Bahri Zouari, I; Charfi, S; Daoud, J; Gouiaa, N; Khabir, A; Sellami Boudawara, T; Toumi, N, 2006) |
| "Although exceptional, multiple myeloma must be borne in mind in the presence of diffuse bone sclerosis." | 1.32 | Multiple myeloma presenting with widespread osteosclerotic lesions. ( Cotten, A; Duquesnoy, B; Flipo, RM; Gaxatte, C; Guillerm, G; Leroy, X; Mulleman, D, 2004) |
| "Spinal cord compression has been reported in 5% of patients with solid tumors." | 1.29 | [Spinal cord compression as the presenting form of non-Hodgkin's lymphoma]. ( Amigo, ML; Caballero, D; del Cañizo, C; Revilla, R; San Miguel, JF; Sánchez, C, 1995) |
| "Epidural hematoma is a rare cause of spinal cord compression, which usually provokes severe neurological deficits." | 1.29 | Cervical spontaneous epidural hematoma as a complication of non-Hodgkin's lymphoma. ( Carletti, S; Frondizi, D; Maira, G; Mastronardi, L; Spera, C, 1996) |
| "Current management of spinal cord compression due to multiple myeloma usually involves irradiation with or without decompressive surgery." | 1.28 | Spinal cord compression in myelomatosis: response to chemotherapy alone. ( Blumsohn, A; Sinoff, CL, 1989) |
| "Four patients suffering spinal cord compression resulting from epidural metastases were treated with adrenocorticosteroid hormones." | 1.26 | "Disappearing" spinal cord compression: oncolytic effect of glucocorticoids (and other chemotherapeutic agents) on epidural metastases. ( Cvitkovic, E; Howieson, J; Posner, JB, 1977) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 17 (44.74) | 18.7374 |
| 1990's | 8 (21.05) | 18.2507 |
| 2000's | 8 (21.05) | 29.6817 |
| 2010's | 5 (13.16) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Fleury, I | 1 |
| Amorim, S | 1 |
| Mounier, N | 1 |
| Coiffier, B | 1 |
| Dupuis, J | 1 |
| Tilly, H | 1 |
| Mazari, MA | 1 |
| Filliatre, L | 1 |
| Brière, J | 1 |
| Brice, P | 1 |
| de Kerviler, E | 1 |
| Thieblemont, C | 1 |
| de Risi-Pugliese, T | 1 |
| Danière, F | 1 |
| Legrand, L | 1 |
| Bancel, P | 1 |
| Oppenheim, C | 1 |
| Wipff, J | 2 |
| Bakker, NA | 1 |
| van Dijk, JM | 1 |
| Slart, RH | 1 |
| Coppes, MH | 1 |
| van Imhoff, GW | 1 |
| Verschuuren, EA | 1 |
| Eagleson, JS | 1 |
| Diaz, J | 1 |
| Platt, SR | 1 |
| Kent, M | 1 |
| Levine, JM | 1 |
| Sharp, NJ | 1 |
| Schatzberg, SJ | 1 |
| Ranasinghe, MG | 1 |
| Zalatimo, O | 1 |
| Rizk, E | 1 |
| Specht, CS | 1 |
| Reiter, GT | 1 |
| Harbaugh, RE | 1 |
| Sheehan, J | 1 |
| Riley, JM | 1 |
| Russo, JK | 1 |
| Shipp, A | 1 |
| Alsharif, M | 1 |
| Jenrette, JM | 1 |
| Logothetis, CJ | 1 |
| Basch, E | 1 |
| Molina, A | 1 |
| Fizazi, K | 1 |
| North, SA | 1 |
| Chi, KN | 1 |
| Jones, RJ | 1 |
| Goodman, OB | 1 |
| Mainwaring, PN | 1 |
| Sternberg, CN | 1 |
| Efstathiou, E | 1 |
| Gagnon, DD | 1 |
| Rothman, M | 1 |
| Hao, Y | 1 |
| Liu, CS | 1 |
| Kheoh, TS | 1 |
| Haqq, CM | 1 |
| Scher, HI | 1 |
| de Bono, JS | 1 |
| IRVINE, RA | 1 |
| ROBERTSON, WB | 1 |
| MUSSHOFF, K | 1 |
| MUELLER, W | 1 |
| FREYBERG, RH | 1 |
| EHRLICH, G | 1 |
| BIENENSTOCK, H | 1 |
| Mulleman, D | 1 |
| Gaxatte, C | 1 |
| Guillerm, G | 1 |
| Leroy, X | 1 |
| Cotten, A | 1 |
| Duquesnoy, B | 1 |
| Flipo, RM | 1 |
| Kaiboriboon, K | 1 |
| Olsen, TJ | 1 |
| Hayat, GR | 1 |
| Allanore, Y | 1 |
| Cormier, C | 1 |
| Redondo, A | 1 |
| Kahan, A | 1 |
| Vaseemuddin, M | 1 |
| Sam, R | 1 |
| Charfi, S | 1 |
| Bahri Zouari, I | 1 |
| Khabir, A | 1 |
| Toumi, N | 1 |
| Gouiaa, N | 1 |
| Daoud, J | 1 |
| Sellami Boudawara, T | 1 |
| Görg, C | 1 |
| Görg, K | 1 |
| Gropp, C | 1 |
| Havemann, K | 1 |
| Gupta, S | 1 |
| Nehru, R | 1 |
| Hierholzer, J | 1 |
| Benndorf, G | 1 |
| Lehmann, T | 1 |
| Schneider, GH | 1 |
| Podrabsky, P | 1 |
| Sander, B | 1 |
| Sörensen, R | 1 |
| Siekmann, R | 1 |
| Stoltenburg, G | 1 |
| Felix, R | 1 |
| Weissman, MN | 1 |
| Lange, R | 1 |
| Kelley, C | 1 |
| Belgea, K | 1 |
| Abel, L | 1 |
| Amigo, ML | 1 |
| Revilla, R | 1 |
| Sánchez, C | 1 |
| del Cañizo, C | 1 |
| Caballero, D | 1 |
| San Miguel, JF | 1 |
| Dujardin, L | 1 |
| Marcelli, C | 1 |
| Hérisson, C | 1 |
| Simon, L | 1 |
| Mastronardi, L | 1 |
| Carletti, S | 1 |
| Frondizi, D | 1 |
| Spera, C | 1 |
| Maira, G | 1 |
| Mora, J | 1 |
| Wollner, N | 1 |
| Fang, Z | 1 |
| Yi, X | 1 |
| Li, M | 1 |
| Zhu, T | 1 |
| Lechtenberg, R | 1 |
| Vaida, GA | 1 |
| Lopes Cardozo, E | 1 |
| Posner, JB | 1 |
| Howieson, J | 1 |
| Cvitkovic, E | 1 |
| Lee, M | 1 |
| Lekias, J | 1 |
| Gubbay, SS | 1 |
| Hurst, PE | 1 |
| Fessler, RG | 1 |
| Johnson, DL | 1 |
| Brown, FD | 1 |
| Erickson, RK | 1 |
| Reid, SA | 1 |
| Kranzler, L | 1 |
| Tsukada, T | 1 |
| Ohno, T | 1 |
| Tsuji, K | 1 |
| Kita, K | 1 |
| Kobayashi, T | 1 |
| Deguchi, K | 1 |
| Shirakawa, S | 1 |
| Sinoff, CL | 1 |
| Blumsohn, A | 1 |
| Haguenau, M | 1 |
| Piette, JC | 1 |
| Robert, G | 1 |
| Vazquez, L | 1 |
| Ellis, A | 1 |
| Saint-Genez, D | 1 |
| Patino, J | 1 |
| Nogues, M | 1 |
| Tobler, WD | 1 |
| Weil, S | 1 |
| Haid, RW | 1 |
| Kaufman, HH | 1 |
| Schochet, SS | 1 |
| Marano, GD | 1 |
| Pui, CH | 1 |
| Dahl, GV | 1 |
| Hustu, HO | 1 |
| Murphy, SB | 1 |
| Kyle, RA | 1 |
| Emery, JP | 1 |
| Lasserre, PP | 1 |
| Dryll, A | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Phase 3, Randomized, Double-Blind, Placebo-Controlled Study of Abiraterone Acetate (CB7630) Plus Prednisone in Patients With Metastatic Castration-Resistant Prostate Cancer Who Have Failed Docetaxel-Based Chemotherapy[NCT00638690] | Phase 3 | 1,195 participants (Actual) | Interventional | 2008-05-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
A prostate-specific antigen (PSA) response was defined as a >=50% decline from baseline. (NCT00638690)
Timeframe: Up to 12 months
| Intervention | Participants (Number) |
|---|---|
| Abiraterone Acetate | 232 |
| Placebo | 22 |
Overall survival is defined as the time interval from the date of randomization to the date of death from any cause. (NCT00638690)
Timeframe: Up to 60 months
| Intervention | Days (Median) |
|---|---|
| Abiraterone Acetate | 450.0 |
| Placebo | 332.0 |
Radiographic progression-free survival is based on imaging studies according to modified Response Evaluation Criteria in Solid Tumors (RECIST): baseline lymph node size must be >=2.0 cm to be considered a target lesion; progression on bone scans with >=2 new lesions not consistent with tumor flare, confirmed on a second scan >=6 weeks later that shows >=1 additional new lesion. (NCT00638690)
Timeframe: Up to 11 months
| Intervention | Days (Median) |
|---|---|
| Abiraterone Acetate | 171.0 |
| Placebo | 110.0 |
The time interval from the date of randomization to the date of the prostate-specific antigen (PSA) progression as defined in the protocol-specific Prostate Specific Antigen Working Group (PSAWG) criteria, namely, a PSA level of at least 5 ng/ml that has risen on at least 2 successive occasions, at least 2 weeks apart. (NCT00638690)
Timeframe: Up to 12 months
| Intervention | Days (Median) |
|---|---|
| Abiraterone Acetate | 309.0 |
| Placebo | 200.0 |
4 reviews available for prednisone and Conus Medullaris Syndrome
| Article | Year |
|---|---|
Epidural lipomatosis: case report and literature review.
Topics: Adult; Diagnosis, Differential; Epidural Space; Heart-Lung Transplantation; Humans; Immunosuppressiv | 1996 |
Epidural lipomatosis in steroid-treated patients.
Topics: Adult; Aged; Epidural Space; Female; Humans; Immunosuppression Therapy; Lipomatosis; Male; Middle Ag | 1992 |
Epidural lipomatosis and renal transplantation.
Topics: Adult; Epidural Space; Humans; Immunosuppressive Agents; Kidney Transplantation; Laminectomy; Lipoma | 1988 |
Multiple myeloma: current therapy and a glimpse of the future.
Topics: Acute Kidney Injury; Anemia; Antibodies, Monoclonal; Antineoplastic Combined Chemotherapy Protocols; | 1985 |
1 trial available for prednisone and Conus Medullaris Syndrome
| Article | Year |
|---|---|
Effect of abiraterone acetate and prednisone compared with placebo and prednisone on pain control and skeletal-related events in patients with metastatic castration-resistant prostate cancer: exploratory analysis of data from the COU-AA-301 randomised tri
Topics: Abiraterone Acetate; Adult; Aged; Aged, 80 and over; Androgen Antagonists; Androstadienes; Bone Neop | 2012 |
33 other studies available for prednisone and Conus Medullaris Syndrome
| Article | Year |
|---|---|
Management and prognosis of 66 patients with B-cell non-Hodgkin lymphoma presenting with initial spinal cord compression: a French retrospective multicenter study.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; B-Lymphocytes; Centr | 2015 |
Extramedullary hematopoiesis with spinal cord compression in pachydermoperiostosis.
Topics: Adult; Decompression, Surgical; Follow-Up Studies; Hematopoiesis, Extramedullary; Humans; Laminectom | 2017 |
Extradural thoracic spinal cord compression: unusual initial presentation of post-transplant lymphoproliferative disorder.
Topics: Adult; alpha 1-Antitrypsin Deficiency; Antineoplastic Combined Chemotherapy Protocols; Cyclophospham | 2008 |
Cervical vertebral malformation-malarticulation syndrome in the Bernese mountain dog: clinical and magnetic resonance imaging features.
Topics: Animals; Anti-Inflammatory Agents; British Columbia; Cervical Vertebrae; Diagnosis, Differential; Do | 2009 |
Idiopathic hypertrophic spinal pachymeningitis.
Topics: Adult; Aged; Dura Mater; Female; Glucocorticoids; Humans; Laminectomy; Magnetic Resonance Imaging; M | 2011 |
Central nervous system myelomatosis with optic neuropathy and intramedullary spinal cord compression responding to radiation therapy.
Topics: Central Nervous System Neoplasms; Dexamethasone; Female; Glucocorticoids; Humans; Magnetic Resonance | 2011 |
SPINAL-CORD COMPRESSION IN THE MALIGNANT LYMPHOMAS.
Topics: Chlorambucil; Hematopoiesis; Hodgkin Disease; Humans; Lymphoma; Lymphoma, Non-Hodgkin; Mercaptopurin | 1964 |
[VERTEBRAL FRACTURES DURING CORTICOSTEROID THERAPY].
Topics: Adrenal Cortex Hormones; Dexamethasone; Fractures, Bone; Humans; Lumbar Vertebrae; Methyltestosteron | 1964 |
[SOME MANIFESTATIONS OF RHEUMATOID DISEASE FREQUENTLY NOT RECOGNIZED OR APPRECIATED].
Topics: Arthritis; Arthritis, Rheumatoid; Cervical Vertebrae; Cortisone; Deglutition Disorders; Hoarseness; | 1964 |
Multiple myeloma presenting with widespread osteosclerotic lesions.
Topics: Aged; Antineoplastic Agents, Alkylating; Antineoplastic Agents, Hormonal; Antineoplastic Combined Ch | 2004 |
Cauda equina and conus medullaris syndrome in sarcoidosis.
Topics: Anti-Inflammatory Agents; Central Nervous System Diseases; Electrodiagnosis; Electromyography; Femal | 2005 |
[Ossification of the common posterior longitudinal ligament of the spine and spinal cord compression in a patient from Senegal].
Topics: Anti-Inflammatory Agents; Back Pain; Erectile Dysfunction; Humans; Longitudinal Ligaments; Magnetic | 2005 |
Large B-cell non-Hodgkin lymphoma.
Topics: Adult; Antibodies, Monoclonal; Antibodies, Monoclonal, Murine-Derived; Antineoplastic Combined Chemo | 2005 |
[Medullary compression revealing the presence of a follicular lymphoma: a case report].
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Cyclophosphamide; | 2006 |
[Aggressive chemotherapy in generalized eosinophilic granuloma in adults].
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Doxorubicin; Eosinophilic G | 1984 |
Rheumatoid arthritis with extra-articular manifestations.
Topics: Adult; Arthritis, Rheumatoid; Humans; Male; Prednisone; Pulmonary Fibrosis; Spinal Cord Compression | 1982 |
Intraspinal epidural sarcoidosis: case report.
Topics: Adult; Combined Modality Therapy; Diagnosis, Differential; Epidural Space; Humans; Laminectomy; Male | 1996 |
[Spinal cord compression as the presenting form of non-Hodgkin's lymphoma].
Topics: Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Cyclophosphamide; Doxorub | 1995 |
[Epidural lipomatosis: complication of long-term corticotherapy. Apropos of 2 cases].
Topics: Adult; Back Pain; Epidural Space; Glucocorticoids; Humans; Lipomatosis; Magnetic Resonance Imaging; | 1996 |
Cervical spontaneous epidural hematoma as a complication of non-Hodgkin's lymphoma.
Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cyclophosphamide; Doxorubicin; Hematoma, | 1996 |
Primary epidural non-Hodgkin lymphoma: spinal cord compression syndrome as the initial form of presentation in childhood non-Hodgkin lymphoma.
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Child; Cyclophosphamide; Daunorubicin; D | 1999 |
Anterior approach to the second thoracic vertebral body for surgical treatment (vertebrectomy, bone grafting, and titanium alloy plate fixation).
Topics: Adult; Alloys; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Bone Plates; Bone Tra | 2001 |
Schistosomiasis of the spinal cord.
Topics: Adult; Benzenesulfonates; Humans; Male; Prednisone; Schistosoma mansoni; Schistosomiasis; Spinal Cor | 1977 |
[Epidural localization of malignant lymphomas with pressure on the spinal cord].
Topics: Aged; Cyclophosphamide; Female; Hodgkin Disease; Humans; Lymphoma, Large B-Cell, Diffuse; Male; Midd | 1977 |
"Disappearing" spinal cord compression: oncolytic effect of glucocorticoids (and other chemotherapeutic agents) on epidural metastases.
Topics: Adolescent; Adult; Aged; Antineoplastic Agents; Dexamethasone; Dysgerminoma; Epidural Space; Humans; | 1977 |
Spinal cord compression by extradural fat after renal transplantation.
Topics: Adolescent; Dura Mater; Humans; Kidney Transplantation; Lipomatosis; Male; Prednisone; Spinal Cord C | 1975 |
Primary epidural non-Hodgkin's lymphoma in clinical stage IEA presenting with paraplegia and showing complete recovery after combination therapy.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Cyclophosphamide; D | 1992 |
Spinal cord compression in myelomatosis: response to chemotherapy alone.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Female; Humans; Male; Melphalan; Middle | 1989 |
[Conference at the Salpêtrière Hospital. June 1987. Progressive spastic paraparesis and dermatomyositis. Epidural lipomatosis during corticosteroid therapy of dermatomyositis].
Topics: Dermatomyositis; Epidural Space; Female; Humans; Lipomatosis; Middle Aged; Paraplegia; Prednisone; S | 1989 |
Epidural lipomatosis after renal transplantation--complete recovery without surgery.
Topics: Adolescent; Diet, Reducing; Epidural Space; Humans; Kidney Transplantation; Lipomatosis; Male; Posto | 1988 |
Epidural lipomatosis simulating an epidural abscess: case report and literature review.
Topics: Abscess; Diagnosis, Differential; Humans; Lipomatosis; Male; Middle Aged; Myelography; Prednisone; S | 1987 |
Epidural spinal cord compression as the initial finding in childhood acute leukemia and non-Hodgkin lymphoma.
Topics: Acute Disease; Adolescent; Child; Child, Preschool; Daunorubicin; Dexamethasone; Female; Humans; Leu | 1985 |
[Peripheral neurologic manifestations of sarcoidosis].
Topics: Adrenal Cortex Hormones; Adult; Cauda Equina; Diagnosis, Differential; Fatigue; Humans; Leg; Male; N | 1972 |