Page last updated: 2024-11-07

prednisone and Connective Tissue Diseases

prednisone has been researched along with Connective Tissue Diseases in 32 studies

Prednisone: A synthetic anti-inflammatory glucocorticoid derived from CORTISONE. It is biologically inert and converted to PREDNISOLONE in the liver.
prednisone : A synthetic glucocorticoid drug that is particularly effective as an immunosuppressant, and affects virtually all of the immune system. Prednisone is a prodrug that is converted by the liver into prednisolone (a beta-hydroxy group instead of the oxo group at position 11), which is the active drug and also a steroid.

Connective Tissue Diseases: A heterogeneous group of disorders, some hereditary, others acquired, characterized by abnormal structure or function of one or more of the elements of connective tissue, i.e., collagen, elastin, or the mucopolysaccharides.

Research Excerpts

ExcerptRelevanceReference
"To evaluate bone status in children born from mothers followed for autoimmune diseases and treated during pregnancy with low molecular weight heparin (LMVH) and/or prednisone."7.80Bone status of children born from mothers with autoimmune diseases treated during pregnancy with prednisone and/or low molecular weight heparin. ( Bellisai, F; Brandi, ML; Cantarini, L; Cavalli, L; Cimaz, R; Frediani, B; Galeazzi, M; Iuliano, A; la Marca, G; Pagnini, I; Simonini, G, 2014)
"We report two cases of hydroxychloroquine-induced hyperpigmentation presenting in a 50-year-old Caucasian female (case 1) and a 78-year-old female (case 2), both receiving 400 mg per day."7.74Hydroxychloroquine-induced hyperpigmentation: the staining pattern. ( Ferringer, T; Lountzis, NI; Puri, PK; Tyler, W, 2008)
"Sirolimus is an effective and safe treatment option for refractory CTD-TP patients."7.01Sirolimus for patients with connective tissue disease-related refractory thrombocytopenia: a single-arm, open-label clinical trial. ( Li, M; Wang, Q; Wu, C; Xu, D; Zeng, X, 2021)
"To evaluate bone status in children born from mothers followed for autoimmune diseases and treated during pregnancy with low molecular weight heparin (LMVH) and/or prednisone."3.80Bone status of children born from mothers with autoimmune diseases treated during pregnancy with prednisone and/or low molecular weight heparin. ( Bellisai, F; Brandi, ML; Cantarini, L; Cavalli, L; Cimaz, R; Frediani, B; Galeazzi, M; Iuliano, A; la Marca, G; Pagnini, I; Simonini, G, 2014)
"We report two cases of hydroxychloroquine-induced hyperpigmentation presenting in a 50-year-old Caucasian female (case 1) and a 78-year-old female (case 2), both receiving 400 mg per day."3.74Hydroxychloroquine-induced hyperpigmentation: the staining pattern. ( Ferringer, T; Lountzis, NI; Puri, PK; Tyler, W, 2008)
" hydroxychloroquine and/or prednisone) were continued during pregnancy."3.73[Perinatal consequences of maternal connective tissue diseases: a prospective study of 73 cases]. ( Costedoat-Chalumeau, N; de Montgolfier, I; Gold, F; Lapillonne, A; Renaud, C; Vautier-Brouzes, D, 2006)
"Sirolimus is an effective and safe treatment option for refractory CTD-TP patients."3.01Sirolimus for patients with connective tissue disease-related refractory thrombocytopenia: a single-arm, open-label clinical trial. ( Li, M; Wang, Q; Wu, C; Xu, D; Zeng, X, 2021)
"When unrecognized and therefore untreated, vasculitis of the nervous system leads to pervasive injury and disability making this a disorder of paramount importance to all clinicians."2.42Vasculitis of the nervous system. ( Younger, DS, 2004)
"We present two patients with systemic lupus erythematosus (SLE) and histopathologically confirmed PNGD."1.56In vivo cutaneous antinuclear antibody positivity in palisaded neutrophilic and granulomatous dermatitis. ( Dong, J; Murphy, M; Storonsky, M; Weston, G; Zubkov, M, 2020)
"Imaging studies showed interstitial pneumonitis and hydropericardium."1.35Undifferentiated connective tissue diseases-related hepatic injury. ( Jia, JD; Wang, BE; Wang, TL; Wu, XN; Zhang, FK; Zhang, Y, 2008)
" The recognition of high NAG enzymuria permits to reduce dosage or discontinue treatment with potentially nephrotoxic drug prior to irreversible renal insufficiency as shown in the case of a patient with psoriatic arthritis treated with simultaneously administered cyclosporin and diclofenac."1.29N-acetyl-beta-D-glucosaminidase enzymuria as an indicator in monitoring the therapy of some rheumatic diseases with potentially nephrotoxic drugs. ( Szechiński, J; Wiland, P, 1994)
"Five developed septic arthritis, including the site of a hip prosthesis in one patient."1.28Salmonella arizona arthritis and septicemia associated with rattlesnake ingestion by patients with connective tissue diseases. A dangerous complication of folk medicine. ( Alarcón-Segovia, D; Guerra-Bautista, G; Kraus, A, 1991)
" Gradual steroid dosage tapering resulted in prompt clinical improvement and marked increases in respiratory muscle strength, maximal inspiratory pressure increasing by 33 percent in one patient and by 70 percent in the other."1.28Corticosteroid-induced myopathy and the respiratory muscles. Report of two cases. ( Decramer, M; Janssens, S, 1989)

Research

Studies (32)

TimeframeStudies, this research(%)All Research%
pre-19908 (25.00)18.7374
1990's9 (28.13)18.2507
2000's5 (15.63)29.6817
2010's7 (21.88)24.3611
2020's3 (9.38)2.80

Authors

AuthorsStudies
Dong, J1
Zubkov, M1
Weston, G1
Storonsky, M1
Murphy, M1
Wu, C1
Wang, Q1
Xu, D1
Li, M1
Zeng, X1
Fronek, L1
Bindernagel, R1
Segars, K1
Miller, R1
Yamano, Y1
Taniguchi, H1
Kondoh, Y1
Ando, M1
Kataoka, K1
Furukawa, T1
Johkoh, T1
Fukuoka, J1
Sakamoto, K1
Hasegawa, Y1
Wilsher, M1
Bruzzese, V1
Zullo, A1
Hassan, C1
Gomes, BF1
Moraes, HV1
Kara-Junior, N1
de Azevedo, MN1
Fonyat de Lima, FB1
Santhiago, MR1
Pagnini, I1
Simonini, G1
Cavalli, L1
la Marca, G1
Iuliano, A1
Brandi, ML1
Bellisai, F1
Frediani, B1
Galeazzi, M2
Cantarini, L1
Cimaz, R1
Puri, PK1
Lountzis, NI1
Tyler, W1
Ferringer, T1
Noaiseh, G1
Bhangle, S1
Vivino, F1
Vaidya, A1
Price, CN1
Lee, YC1
DELLA CORTE, M1
GIANI, E1
Younger, DS1
Renaud, C1
de Montgolfier, I1
Vautier-Brouzes, D1
Costedoat-Chalumeau, N1
Lapillonne, A1
Gold, F1
Zhang, Y1
Zhang, FK1
Wu, XN1
Wang, TL1
Jia, JD1
Wang, BE1
Gennari, C1
Imbimbo, B2
Montagnani, M1
Bernini, M1
Nardi, P1
Avioli, LV1
Hasselbalch, H1
Russell, IJ1
Conn, DL1
McKenna, CH1
Stobo, JD1
Winkelmann, RK1
Padilha-Goncalves, A1
Bacon, BR1
Treuhaft, WH1
Goodman, AM1
Wiland, P1
Szechiński, J1
Godeau, B1
Coutant-Perronne, V1
Le Thi Huong, D1
Guillevin, L1
Magadur, G1
De Bandt, M1
Dellion, S1
Rossert, J1
Rostoker, G1
Piette, JC1
Ruiz-Argüelles, GJ1
Ruiz-Argüelles, A1
Pérez-Romano, B1
Alarcón-Segovia, D2
Aicardi, G2
Benso, L1
Vignolo, M2
Terragna, A2
Verrina, E1
Cordone, G2
Coppo, R2
Sernia, O1
Sardella, ML1
Di Battista, E2
Mascarenhas, MR1
McGowan, KL1
Ruchelli, E1
Athreya, B1
Altschuler, SM1
Daly, EF1
Kubiak, NT1
McMurray, R1
Renzoni, E1
Rottoli, P1
Coviello, G1
Perari, MG1
Vagliasindi, M1
Vondra, K1
Hampl, R1
Nĕmcová, D1
Hill, M1
Hoza, J1
Kot'átková, A1
Stárka, L1
Vrbíková, J1
Zamrazil, V1
Kraus, A1
Guerra-Bautista, G1
Milani, S1
Gusmano, R1
Cottafava, F1
Janssens, S1
Decramer, M1
Peretz, A1
Praet, JP1
Bosson, D1
Rozenberg, S1
Bourdoux, P1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Sirolimus in Patients With Connective Tissue Disease Related Thrombocytopenia (CTD-TP): a Single-arm, Open-label Clinical Trial in China[NCT03688191]Phase 420 participants (Anticipated)Interventional2017-09-21Active, not recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for prednisone and Connective Tissue Diseases

ArticleYear
Vasculitis of the nervous system.
    Current opinion in neurology, 2004, Volume: 17, Issue:3

    Topics: Azathioprine; Connective Tissue Diseases; Cyclophosphamide; Diagnosis, Differential; Giant Cell Arte

2004

Trials

3 trials available for prednisone and Connective Tissue Diseases

ArticleYear
Sirolimus for patients with connective tissue disease-related refractory thrombocytopenia: a single-arm, open-label clinical trial.
    Rheumatology (Oxford, England), 2021, 06-18, Volume: 60, Issue:6

    Topics: Administration, Oral; Adolescent; Adult; Connective Tissue Diseases; Female; Glucocorticoids; Humans

2021
Dose-dependent effects of deflazacort and prednisone on growth and skeletal maturation.
    British journal of rheumatology, 1993, Volume: 32 Suppl 2

    Topics: Age Determination by Skeleton; Anti-Inflammatory Agents; Body Height; Body Weight; Child; Child, Pre

1993
Comparison of growth retarding effects induced by two different glucocorticoids in prepubertal sick children: an interim long-term analysis.
    Calcified tissue international, 1991, Volume: 48, Issue:4

    Topics: Age Determination by Skeleton; Body Height; Body Weight; Child; Child, Preschool; Connective Tissue

1991

Other Studies

28 other studies available for prednisone and Connective Tissue Diseases

ArticleYear
In vivo cutaneous antinuclear antibody positivity in palisaded neutrophilic and granulomatous dermatitis.
    Journal of cutaneous pathology, 2020, Volume: 47, Issue:10

    Topics: Adult; Aged; Antibodies, Antinuclear; Biopsy; Connective Tissue Diseases; Dermatitis; Diagnosis, Dif

2020
Multicentric reticulohistiocytosis masquerading as cutaneous connective tissue disease.
    Dermatology online journal, 2021, Mar-15, Volume: 27, Issue:3

    Topics: Aged, 80 and over; Connective Tissue Diseases; Dermatologic Agents; Dermatomyositis; Diagnosis, Diff

2021
Multidimensional improvement in connective tissue disease-associated interstitial lung disease: Two courses of pulse dose methylprednisolone followed by low-dose prednisone and tacrolimus.
    Respirology (Carlton, Vic.), 2018, Volume: 23, Issue:11

    Topics: Aged; Connective Tissue Diseases; Drug Therapy, Combination; Female; Humans; Immunosuppressive Agent

2018
Managing disease behaviour: A team approach.
    Respirology (Carlton, Vic.), 2018, Volume: 23, Issue:11

    Topics: Connective Tissue Diseases; Humans; Lung Diseases, Interstitial; Methylprednisolone; Prednisone; Tac

2018
Connective tissue disease following hepatitis B vaccination.
    Journal of clinical rheumatology : practical reports on rheumatic & musculoskeletal diseases, 2013, Volume: 19, Issue:5

    Topics: Adult; Antirheumatic Agents; Connective Tissue Diseases; Female; Glucocorticoids; Hepatitis B Vaccin

2013
Intraocular pressure in chronic users of low-dose oral corticosteroids for connective tissue disease.
    Canadian journal of ophthalmology. Journal canadien d'ophtalmologie, 2014, Volume: 49, Issue:4

    Topics: Administration, Oral; Connective Tissue Diseases; Cross-Sectional Studies; Female; Glucocorticoids;

2014
Bone status of children born from mothers with autoimmune diseases treated during pregnancy with prednisone and/or low molecular weight heparin.
    Pediatric rheumatology online journal, 2014, Volume: 12

    Topics: Autoimmune Diseases; Bone and Bones; Bone Resorption; Child; Child, Preschool; Connective Tissue Dis

2014
Hydroxychloroquine-induced hyperpigmentation: the staining pattern.
    Journal of cutaneous pathology, 2008, Volume: 35, Issue:12

    Topics: Aged; Antacids; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents

2008
Idiopathic mediastinal fibrosis presenting with antiphospholipid antibody syndrome and manifestations suggestive of connective tissue disease.
    Journal of clinical rheumatology : practical reports on rheumatic & musculoskeletal diseases, 2012, Volume: 18, Issue:3

    Topics: Antibodies, Anticardiolipin; Antiphospholipid Syndrome; Antirheumatic Agents; Azathioprine; Connecti

2012
Interactive medical case. Disconnected.
    The New England journal of medicine, 2012, Aug-16, Volume: 367, Issue:7

    Topics: Anti-Inflammatory Agents; Antibodies, Antinuclear; Arthralgia; Atrial Fibrillation; Chest Pain; Colc

2012
[Prevention of peritoneal adhesions by various steroids (cortisone, prednisone and triamcinolone); experimental studies].
    Giornale italiano di chirurgia, 1958, Volume: 14, Issue:11

    Topics: Connective Tissue Diseases; Cortisone; Fludrocortisone; Peritoneal Diseases; Prednisolone; Prednison

1958
[Perinatal consequences of maternal connective tissue diseases: a prospective study of 73 cases].
    Archives de pediatrie : organe officiel de la Societe francaise de pediatrie, 2006, Volume: 13, Issue:11

    Topics: Adult; Connective Tissue Diseases; Female; Glucocorticoids; Humans; Hydroxychloroquine; Infant, Newb

2006
Undifferentiated connective tissue diseases-related hepatic injury.
    World journal of gastroenterology, 2008, May-07, Volume: 14, Issue:17

    Topics: Connective Tissue Diseases; Diagnosis, Differential; Female; Glucocorticoids; Humans; Liver Diseases

2008
Effects of prednisone and deflazacort on mineral metabolism and parathyroid hormone activity in humans.
    Calcified tissue international, 1984, Volume: 36, Issue:3

    Topics: Aged; Alkaline Phosphatase; Asthma; Bone and Bones; Bone Resorption; Calcium; Connective Tissue Dise

1984
Hairy-cell leukaemia simulating connective tissue disease.
    Scandinavian journal of haematology, 1984, Volume: 32, Issue:5

    Topics: Bone Marrow; Connective Tissue Diseases; Diagnosis, Differential; Humans; Leukemia, Hairy Cell; Live

1984
Augmentation of immunoglobulin production in connective tissue disorders.
    Clinical immunology and immunopathology, 1980, Volume: 16, Issue:2

    Topics: Adult; Antibody-Producing Cells; Connective Tissue Diseases; Female; Humans; Hypergammaglobulinemia;

1980
Connective tissue panniculitis.
    Archives of dermatology, 1980, Volume: 116, Issue:3

    Topics: Adipose Tissue; Adolescent; Adult; Antigen-Antibody Reactions; Atrophy; Biopsy; Connective Tissue Di

1980
Azathioprine-induced pancytopenia. Occurrence in two patients with connective-tissue diseases.
    Archives of internal medicine, 1981, Volume: 141, Issue:2

    Topics: Adult; Arthritis, Juvenile; Azathioprine; Blood Cell Count; Bone Marrow; Connective Tissue Diseases;

1981
N-acetyl-beta-D-glucosaminidase enzymuria as an indicator in monitoring the therapy of some rheumatic diseases with potentially nephrotoxic drugs.
    Archivum immunologiae et therapiae experimentalis, 1994, Volume: 42, Issue:4

    Topics: Acetylglucosaminidase; Adolescent; Adult; Aged; Aminoglycosides; Anti-Bacterial Agents; Anti-Inflamm

1994
Pneumocystis carinii pneumonia in the course of connective tissue disease: report of 34 cases.
    The Journal of rheumatology, 1994, Volume: 21, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Connective Tissue Diseases; Cyclophosphamide; Female; Humans; Immuno

1994
Protein S deficiency associated to anti-protein S antibodies in a patient with mixed connective-tissue disease and its reversal by danazol.
    Acta haematologica, 1993, Volume: 89, Issue:4

    Topics: Adult; Antiphospholipid Syndrome; Autoantibodies; Connective Tissue Diseases; Danazol; Female; Human

1993
Acremonium infection of the esophagus.
    Journal of pediatric gastroenterology and nutrition, 1997, Volume: 24, Issue:3

    Topics: Acremonium; Barrett Esophagus; Child, Preschool; Cimetidine; Connective Tissue Diseases; Esophageal

1997
Case records of the Department of Medicine University of Mississippi Medical Center. Leukocytoclastic vasculitis, probable polyarteritis nodosa, clinically indolent lymphoma, but never firmly established.
    Journal of the Mississippi State Medical Association, 1997, Volume: 38, Issue:9

    Topics: Aged; Biopsy; Connective Tissue Diseases; Cyclophosphamide; Diagnosis, Differential; Drug Therapy, C

1997
Clinical, laboratory and radiological findings in pulmonary fibrosis with and without connective tissue disease.
    Clinical rheumatology, 1997, Volume: 16, Issue:6

    Topics: Antibodies, Antinuclear; Bronchoalveolar Lavage Fluid; Connective Tissue Diseases; Diagnosis, Differ

1997
[Role of the steroids, SHBG, IGF-1, IGF BP-3 and growth hormone in glucose metabolism disorders during long-term treatment with low doses of glucocorticoids].
    Casopis lekaru ceskych, 2002, Feb-15, Volume: 141, Issue:3

    Topics: Adolescent; Adult; Androgens; Connective Tissue Diseases; Female; Glucocorticoids; Glucose; Growth H

2002
Salmonella arizona arthritis and septicemia associated with rattlesnake ingestion by patients with connective tissue diseases. A dangerous complication of folk medicine.
    The Journal of rheumatology, 1991, Volume: 18, Issue:9

    Topics: Adolescent; Adult; Animals; Arthritis, Infectious; Azathioprine; Connective Tissue Diseases; Drug Th

1991
Corticosteroid-induced myopathy and the respiratory muscles. Report of two cases.
    Chest, 1989, Volume: 95, Issue:5

    Topics: Connective Tissue Diseases; Dermatomyositis; Dyspnea; Female; Humans; Middle Aged; Muscular Diseases

1989
Serum osteocalcin in the assessment of corticosteroid induced osteoporosis. Effect of long and short term corticosteroid treatment.
    The Journal of rheumatology, 1989, Volume: 16, Issue:3

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Biomarkers; Bone and Bones; Calcium-Binding Proteins; Co

1989