Page last updated: 2024-11-07

prednisone and Conjunctival Diseases

prednisone has been researched along with Conjunctival Diseases in 15 studies

Prednisone: A synthetic anti-inflammatory glucocorticoid derived from CORTISONE. It is biologically inert and converted to PREDNISOLONE in the liver.
prednisone : A synthetic glucocorticoid drug that is particularly effective as an immunosuppressant, and affects virtually all of the immune system. Prednisone is a prodrug that is converted by the liver into prednisolone (a beta-hydroxy group instead of the oxo group at position 11), which is the active drug and also a steroid.

Conjunctival Diseases: Diseases involving the CONJUNCTIVA.

Research Excerpts

ExcerptRelevanceReference
"To report the authors' experience with azathioprine and prednisone combination for adult periocular and orbital xanthogranulomatous disease."7.77Azathioprine and prednisone combination treatment for adult periocular and orbital xanthogranulomatous disease. ( Bijlsma, WR; Paridaens, D; van Daele, PL; van den Bosch, WA, 2011)
"To report the authors' experience with azathioprine and prednisone combination for adult periocular and orbital xanthogranulomatous disease."3.77Azathioprine and prednisone combination treatment for adult periocular and orbital xanthogranulomatous disease. ( Bijlsma, WR; Paridaens, D; van Daele, PL; van den Bosch, WA, 2011)
"Pain is historically considered a cardinal sign of acute inflammation and a predominant symptom of IOIS."2.46Idiopathic orbital inflammatory syndrome without pain: a case report. ( Boothe, KH; Eckermann, DR; Musick, AN; Slagle, AM; Slagle, WS, 2010)
" EBV-related polymorphic PTLD was diagnosed and treated with discontinuation of cyclosporine, reduction in prednisone dosage and administration of EBV-specific cytotoxic T lymphocytes."1.34Conjunctival posttransplantation lymphoproliferative disorder. ( Irshad, FA; Onciu, MM; Walton, RC; Wilson, TD, 2007)
"A patient with a conjunctival blister was diagnosed with pemphigus vulgaris by immunofluorescence tests performed on a conjunctival biopsy."1.33[Conjunctival blistering associated with pemphigus vulgaris: report of a case]. ( Alvarez, MA; Bianciotto, C; Herreras Cantalapiedra, JM; Méndez Díaz, MC, 2005)
"Human cysticercosis is secondary to an infestation by cysticercus cellulosae, the larval form of Taenia solium."1.30Orbital cysticercosis. ( Lemke, BN; Sekhar, GC, 1997)
"Microscopic polyangiitis is an exclusively small-vessel (arterioles, capillaries, or venules) vasculitis that primarily involves the kidney and often involves the lungs, skin, or nervous system."1.29Microscopic polyangiitis with ocular involvement. ( Caster, JC; Pappolla, MA; Shetlar, DJ; Yee, RW, 1996)

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-19901 (6.67)18.7374
1990's2 (13.33)18.2507
2000's8 (53.33)29.6817
2010's4 (26.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Chen, D1
Min, HY1
Jankauskiene, A1
Buteikiene, I1
Thorne, JE2
Woreta, FA1
Jabs, DA3
Anhalt, GJ1
Bijlsma, WR1
van den Bosch, WA1
van Daele, PL1
Paridaens, D1
Slagle, WS1
Boothe, KH1
Musick, AN1
Eckermann, DR1
Slagle, AM1
Paulus, YM1
Cockerham, KP1
Cockerham, GC1
Gratzinger, D1
Mokete, B1
Thompson, GM1
Bianciotto, C1
Herreras Cantalapiedra, JM1
Alvarez, MA1
Méndez Díaz, MC1
Qazi, FA1
Nguyen, QD1
Kempen, JH1
Dunn, JP1
Ah-Chan, JJ1
Molteno, AC1
Bevin, TH1
Walton, RC1
Onciu, MM1
Irshad, FA1
Wilson, TD1
Foster, CS1
Wilson, LA1
Ekins, MB1
Caster, JC1
Shetlar, DJ1
Pappolla, MA1
Yee, RW1
Sekhar, GC1
Lemke, BN1
Farr, AK1
Green, WR1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Myfortic (Enteric-coated Mycophenolate Sodium) for the Treatment of Non-infectious Intermediate Uveitis - a Prospective, Controlled, Randomized Multicenter Trial[NCT01092533]Phase 344 participants (Actual)Interventional2010-03-31Completed
First-line Antimetabolites as Steroid-sparing Treatment (FAST) Uveitis Trial[NCT01829295]Phase 3216 participants (Actual)Interventional2013-08-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Number of Participants Achieving Treatment Success After Switching to Other Medication (Phase II, 0-6 Months)

Controlled ocular inflammation (≤ 0.5+ anterior chamber cells, ≤ 0.5+ vitreous haze, no active retinal/choroidal lesions in both eyes) with 7.5 mg/day of oral prednisone and ≤ 2 drops/day of topical 1% prednisolone acetate for patients who crossed over to other medication following treatment failure at 6 months (or earlier). (NCT01829295)
Timeframe: 6 Months

InterventionParticipants (Count of Participants)
Switched Over to Methotrexate20
Switched Over to Mycophenolate Mofetil7

Number of Participants Achieving Treatment Success at 12 Months on Same Medication (Phase I, 6-12 Months)

Controlled ocular inflammation (≤ 0.5+ anterior chamber cells, ≤ 0.5+ vitreous haze, no active retinal/choroidal lesions in both eyes) with 7.5 mg/day of oral prednisone and ≤ 2 drops/day of topical 1% prednisolone acetate in patients who were a treatment success at the primary outcome of 6 months. (NCT01829295)
Timeframe: 12 Months

InterventionParticipants (Count of Participants)
Methotrexate48
Mycophenolate Mofetil40

Number of Participants Achieving Treatment Success at 6 Months (Phase I, 0-6 Months)

Controlled ocular inflammation (≤ 0.5+ anterior chamber cells, ≤ 0.5+ vitreous haze, no active retinal/choroidal lesions in both eyes) with 7.5 mg/day of oral prednisone and ≤ 2 drops/day of topical 1% prednisolone acetate. (NCT01829295)
Timeframe: 6 Months

InterventionParticipants (Count of Participants)
Methotrexate64
Mycophenolate Mofetil56

Reviews

1 review available for prednisone and Conjunctival Diseases

ArticleYear
Idiopathic orbital inflammatory syndrome without pain: a case report.
    Optometry (St. Louis, Mo.), 2010, Volume: 81, Issue:3

    Topics: Aged; Conjunctival Diseases; Dacryocystitis; Diagnosis, Differential; Edema; Humans; Inflammation; M

2010

Other Studies

14 other studies available for prednisone and Conjunctival Diseases

ArticleYear
Conjunctival langerhans cell histiocytosis: a case report.
    Chinese medical sciences journal = Chung-kuo i hsueh k'o hsueh tsa chih, 2015, Volume: 30, Issue:1

    Topics: Conjunctival Diseases; Cyclophosphamide; Cyclosporine; Female; Histiocytosis, Langerhans-Cell; Human

2015
Severe chemosis in a patient with nephrotic syndrome.
    European journal of pediatrics, 2009, Volume: 168, Issue:4

    Topics: Adolescent; Albumins; Angiotensin-Converting Enzyme Inhibitors; Conjunctival Diseases; Cyclosporine;

2009
Treatment of ocular mucous membrane pemphigoid with immunosuppressive drug therapy.
    Ophthalmology, 2008, Volume: 115, Issue:12

    Topics: Adult; Aged; Aged, 80 and over; Conjunctival Diseases; Cyclophosphamide; Female; Humans; Immunosuppr

2008
Azathioprine and prednisone combination treatment for adult periocular and orbital xanthogranulomatous disease.
    Acta ophthalmologica, 2011, Volume: 89, Issue:3

    Topics: Adult; Aged; Azathioprine; Conjunctival Diseases; Drug Therapy, Combination; Eye Diseases; Eyelid Di

2011
IgG4-positive sclerosing orbital inflammation involving the conjunctiva: a case report.
    Ocular immunology and inflammation, 2012, Volume: 20, Issue:5

    Topics: Aged; Anti-Inflammatory Agents; Antibodies, Antineutrophil Cytoplasmic; Biopsy; C-Reactive Protein;

2012
Giant fornix syndrome.
    Ophthalmology, 2005, Volume: 112, Issue:6

    Topics: Aged; Aged, 80 and over; Anti-Bacterial Agents; Blepharospasm; Botulinum Toxins, Type A; Conjunctiva

2005
[Conjunctival blistering associated with pemphigus vulgaris: report of a case].
    Archivos de la Sociedad Espanola de Oftalmologia, 2005, Volume: 80, Issue:6

    Topics: Aged; Autoantibodies; Autoimmune Diseases; Biopsy; Blister; Conjunctiva; Conjunctival Diseases; Fluo

2005
Mycophenolate mofetil therapy for inflammatory eye disease.
    Ophthalmology, 2005, Volume: 112, Issue:8

    Topics: Adolescent; Adult; Aged; Child; Conjunctival Diseases; Drug Therapy, Combination; Female; Glucocorti

2005
Mycophenolate mofetil therapy for inflammatory eye disease.
    Ophthalmology, 2005, Volume: 112, Issue:8

    Topics: Adolescent; Adult; Aged; Child; Conjunctival Diseases; Drug Therapy, Combination; Female; Glucocorti

2005
Mycophenolate mofetil therapy for inflammatory eye disease.
    Ophthalmology, 2005, Volume: 112, Issue:8

    Topics: Adolescent; Adult; Aged; Child; Conjunctival Diseases; Drug Therapy, Combination; Female; Glucocorti

2005
Mycophenolate mofetil therapy for inflammatory eye disease.
    Ophthalmology, 2005, Volume: 112, Issue:8

    Topics: Adolescent; Adult; Aged; Child; Conjunctival Diseases; Drug Therapy, Combination; Female; Glucocorti

2005
Anti-inflammatory fibrosis suppression in threatened trabeculectomy bleb failure.
    Archives of ophthalmology (Chicago, Ill. : 1960), 2006, Volume: 124, Issue:4

    Topics: Aged; Anti-Inflammatory Agents; Chronic Disease; Colchicine; Conjunctiva; Conjunctival Diseases; Dic

2006
Conjunctival posttransplantation lymphoproliferative disorder.
    American journal of ophthalmology, 2007, Volume: 143, Issue:6

    Topics: Biomarkers; Bone Marrow Transplantation; Child; Conjunctival Diseases; Cyclosporine; DNA, Viral; Eps

2007
Immunosuppressive therapy for progressive ocular cicatricial pemphigoid.
    Ophthalmology, 1982, Volume: 89, Issue:4

    Topics: Adult; Aged; Azathioprine; Cicatrix; Conjunctival Diseases; Corneal Diseases; Cyclophosphamide; Drug

1982
Microscopic polyangiitis with ocular involvement.
    Archives of ophthalmology (Chicago, Ill. : 1960), 1996, Volume: 114, Issue:3

    Topics: Adult; Anti-Inflammatory Agents; Conjunctiva; Conjunctival Diseases; Cyclophosphamide; Eyelid Diseas

1996
Orbital cysticercosis.
    Ophthalmology, 1997, Volume: 104, Issue:10

    Topics: Adolescent; Adult; Albendazole; Animals; Anthelmintics; Child; Child, Preschool; Conjunctiva; Conjun

1997
Optic disc sarcoid granuloma.
    Archives of ophthalmology (Chicago, Ill. : 1960), 2000, Volume: 118, Issue:5

    Topics: Adult; Conjunctival Diseases; Female; Glucocorticoids; Granuloma; Humans; Optic Disk; Optic Nerve Di

2000