prednisone has been researched along with Chorea in 42 studies
Prednisone: A synthetic anti-inflammatory glucocorticoid derived from CORTISONE. It is biologically inert and converted to PREDNISOLONE in the liver.
prednisone : A synthetic glucocorticoid drug that is particularly effective as an immunosuppressant, and affects virtually all of the immune system. Prednisone is a prodrug that is converted by the liver into prednisolone (a beta-hydroxy group instead of the oxo group at position 11), which is the active drug and also a steroid.
Chorea: Involuntary, forcible, rapid, jerky movements that may be subtle or become confluent, markedly altering normal patterns of movement. Hypotonia and pendular reflexes are often associated. Conditions which feature recurrent or persistent episodes of chorea as a primary manifestation of disease are referred to as CHOREATIC DISORDERS. Chorea is also a frequent manifestation of BASAL GANGLIA DISEASES.
Excerpt | Relevance | Reference |
---|---|---|
"In this randomized, double-blind, parallel study of a group of 22 children and teenagers, prednisone efficacy in acute Sydenham's chorea was assessed." | 9.12 | Randomized double-blind study with prednisone in Sydenham's chorea. ( Marques-Dias, MJ; Paz, JA; Silva, CA, 2006) |
"Sydenham's chorea has been established as a postinfectious autoimmune neuropsychiatric disorder." | 6.71 | Treatment of Sydenham's chorea with intravenous immunoglobulin, plasma exchange, or prednisone. ( Garvey, MA; Leitman, SF; Snider, LA; Swedo, SE; Werden, R, 2005) |
"Clinical information of children with Sydenham chorea were collected." | 5.56 | Preliminary data on prednisone effectiveness in children with Sydenham chorea. ( Cimaz, R; Di Mascio, A; Favaretto, E; Gortani, G; Pastore, S; Simonini, G; Taddio, A, 2020) |
"Neurocysticercosis is the most common parasitic infection of the central nervous system." | 5.33 | Resolution of arterial stenosis in a patient with periarterial neurocysticercosis treated with oral prednisone. ( Bouldin, A; Pinter, JD, 2006) |
"In this randomized, double-blind, parallel study of a group of 22 children and teenagers, prednisone efficacy in acute Sydenham's chorea was assessed." | 5.12 | Randomized double-blind study with prednisone in Sydenham's chorea. ( Marques-Dias, MJ; Paz, JA; Silva, CA, 2006) |
"Sydenham's chorea has been established as a postinfectious autoimmune neuropsychiatric disorder." | 2.71 | Treatment of Sydenham's chorea with intravenous immunoglobulin, plasma exchange, or prednisone. ( Garvey, MA; Leitman, SF; Snider, LA; Swedo, SE; Werden, R, 2005) |
"Clinical information of children with Sydenham chorea were collected." | 1.56 | Preliminary data on prednisone effectiveness in children with Sydenham chorea. ( Cimaz, R; Di Mascio, A; Favaretto, E; Gortani, G; Pastore, S; Simonini, G; Taddio, A, 2020) |
"Sydenham chorea is not an unusual complication of rheumatic fever." | 1.35 | [Acute poststreptoccocal chorea: an atypical postoperative reaction following cardiac surgery for mitral valvulopathy]. ( Abadie, V; Bahi-Buisson, N; Brousse, V; Deloche, A; Lucet, V, 2009) |
"Prednisone treatment may lead to a shortened course of chorea (4." | 1.34 | Rheumatic chorea: relationship to systemic manifestations and response to corticosteroids. ( Bale, JF; Firth, SD; Tani, LY; Thompson, JA; Veasy, LG; Walker, AR, 2007) |
"Neurocysticercosis is the most common parasitic infection of the central nervous system." | 1.33 | Resolution of arterial stenosis in a patient with periarterial neurocysticercosis treated with oral prednisone. ( Bouldin, A; Pinter, JD, 2006) |
"Primary antiphospholipid antibody syndrome is rarely complicated by chorea, but should be taken into consideration in patients who do not fulfill the diagnostic criteria for SLE." | 1.29 | Chorea in primary antiphospholipid syndrome. ( Antonini, G; Masala, C; Morino, S; Zangari, P, 1996) |
"The appearance of chorea due to systemic lupus erythematosus is extremely rare." | 1.28 | [Chorea and systemic lupus erythematosus]. ( Aladro, Y; Amérigo, MJ; Antolín, J; Artiles, J; Cárdenes, MA; Gómez, E, 1990) |
"A clinical diagnosis of systemic lupus erythematosus (SLE) was made in four women." | 1.27 | Lupus anticoagulant in pregnancy. ( Butler, WS; Liggins, GC; Lubbe, WF; Palmer, SJ, 1984) |
"Neurologic complications of systemic lupus erythematosus (SLE) are common, but chorea is rare." | 1.25 | Clinical features of chorea associated with systemic lupus erythematosus. ( Lusins, JO; Szilagyi, PA, 1975) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 20 (47.62) | 18.7374 |
1990's | 9 (21.43) | 18.2507 |
2000's | 8 (19.05) | 29.6817 |
2010's | 4 (9.52) | 24.3611 |
2020's | 1 (2.38) | 2.80 |
Authors | Studies |
---|---|
Favaretto, E | 1 |
Gortani, G | 1 |
Simonini, G | 1 |
Pastore, S | 1 |
Di Mascio, A | 1 |
Cimaz, R | 1 |
Taddio, A | 1 |
El Otmani, H | 1 |
Moutaouakil, F | 1 |
Fadel, H | 1 |
Slassi, I | 1 |
Ataia, I | 1 |
Casaulta, C | 1 |
von Vigier, RO | 1 |
Pfammatter, JP | 1 |
Brekenfeld, C | 1 |
Sauvain, MJ | 1 |
Steinlin, M | 1 |
Brousse, V | 1 |
Bahi-Buisson, N | 1 |
Lucet, V | 1 |
Deloche, A | 1 |
Abadie, V | 1 |
Ishaq, S | 1 |
Khalil, S | 1 |
Khan, A | 1 |
Khalid, U | 1 |
Masannat, Y | 1 |
Gandhy, R | 1 |
Olajide, O | 1 |
Kheetan, R | 1 |
Yaqub, A | 1 |
Gumus, H | 1 |
Gumus, G | 1 |
Per, H | 1 |
Yikilmaz, A | 1 |
Canpolat, M | 1 |
Poyrazoglu, G | 1 |
Narin, N | 1 |
LANZA, I | 2 |
MORBIDELLI, R | 2 |
GAYOTTO, F | 2 |
NEBO, F | 2 |
SPILBORGHS, G | 2 |
ROWE, PB | 1 |
MUEHLER, E | 1 |
GROS, H | 1 |
AUDIER, M | 1 |
SALVINI, A | 1 |
MAGARDITCHIAN, A | 1 |
PANOFF, A | 1 |
Barash, J | 1 |
Margalith, D | 1 |
Matitiau, A | 1 |
Garvey, MA | 2 |
Snider, LA | 1 |
Leitman, SF | 1 |
Werden, R | 1 |
Swedo, SE | 3 |
Teixeira, AL | 1 |
Cardoso, F | 1 |
Paz, JA | 1 |
Silva, CA | 1 |
Marques-Dias, MJ | 1 |
Bouldin, A | 1 |
Pinter, JD | 1 |
Walker, AR | 1 |
Tani, LY | 1 |
Thompson, JA | 1 |
Firth, SD | 1 |
Veasy, LG | 1 |
Bale, JF | 1 |
Lubbe, WF | 2 |
Walker, EB | 1 |
Butler, WS | 1 |
Palmer, SJ | 1 |
Liggins, GC | 1 |
Astulfoni, A | 1 |
D'Agostino, M | 1 |
Bergonzi, F | 1 |
Van Horn, G | 1 |
Arnett, FC | 1 |
Dimachkie, MM | 1 |
Masala, C | 1 |
Morino, S | 1 |
Zangari, P | 1 |
Antonini, G | 1 |
Rebeś, Z | 1 |
Oszukowski, P | 1 |
Wilczyński, J | 1 |
Lisiewicz, J | 1 |
Wendorff, J | 1 |
Song, CH | 1 |
Oftadeh, LC | 1 |
Oh, C | 1 |
Louie, J | 1 |
Yu, KT | 1 |
Brown, WT | 1 |
Sanberg, PR | 1 |
McGeer, PL | 1 |
Green, LN | 1 |
Lusins, JO | 1 |
Szilagyi, PA | 1 |
Pavlakis, SG | 1 |
Schneider, S | 1 |
Black, K | 1 |
Gould, RJ | 1 |
Antolín, J | 1 |
Amérigo, MJ | 1 |
Gómez, E | 1 |
Cárdenes, MA | 1 |
Artiles, J | 1 |
Aladro, Y | 1 |
Pincemaille, O | 1 |
Jeannoel, P | 1 |
Pouzol, P | 1 |
Plantaz, D | 1 |
Bost, M | 1 |
Schieken, R | 1 |
Anderson, WT | 1 |
Anthony, CL | 1 |
Corvol, P | 1 |
Lagrue, G | 1 |
Marteau, R | 1 |
Milliez, P | 1 |
Konbar, AA | 1 |
Guirguis, FK | 1 |
Abdel-Hay, MM | 1 |
Grossman, BJ | 1 |
Behrend, T | 1 |
Tahernia, AC | 1 |
Moatamed, F | 1 |
Sharif, H | 1 |
Heffron, WA | 1 |
Appenzeller, O | 1 |
Fritel, G | 1 |
Harpey, JP | 1 |
Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
---|---|---|---|---|---|---|---|
Childhood Onset Psychiatric Disorders: A Placebo Controlled Double-Blind Crossover Trial of Intravenous Immunoglobulin (IVIg)[NCT00001768] | Phase 3 | 10 participants | Interventional | 1997-10-31 | Completed | ||
Intravenous Immunoglobulins as Effective Treatment in Sydenham's Chorea[NCT00615797] | 20 participants (Actual) | Interventional | 2002-05-31 | Completed | |||
Pattern and Frequency of Non-epileptic Involuntary Movements. Hospital-based Study[NCT04083586] | 144 participants (Actual) | Observational | 2020-01-15 | Completed | |||
Antibiotic Treatment Trial for the PANDAS/PANS Phenotype[NCT01617083] | Phase 2 | 47 participants (Actual) | Interventional | 2012-05-31 | Completed | ||
[information is prepared from clinicaltrials.gov, extracted Sep-2024] |
The CYBOCS is a clinician rated, semi-structured interview for rating the severity of OCD (Scahill, et al., 1997). Total scores range from 0 to 50, with higher scores representing greater severity. The total score is comprised of two subscores, obsessions and compulsions, each with a range of 0-25. (NCT01617083)
Timeframe: Before and after 4 week randomization
Intervention | units on a scale (Mean) | |
---|---|---|
Baseline | After 4 week randomization | |
Azithromycin | 29.49 | 20.53 |
Placebo | 28.43 | 23.45 |
The CGI-S scale is a 7-point clinician rating of severity of psychopathology. Severity ratings range from 1 (no illness) to 7 (extremely severe). This instrument has been successfully used in treatment studies (Cook, et al., 2001; Storch, et al., 2007). (NCT01617083)
Timeframe: Before and after 4 week randomization
Intervention | units on a scale (Mean) | |
---|---|---|
Baseline | After 4 week randomization | |
Azithromycin | 5.24 | 4.06 |
Placebo | 5.00 | 4.93 |
The Screen for Childhood Anxiety-Related Emotional Disorders (SCARED) is a 41-item parent and participant-completed tool used to measure symptoms of anxiety, including the most common symptoms of panic/somatic, generalized anxiety, separation anxiety, social phobia, and school phobia. Scores range from 0-82, with higher scores indicating more severe symptoms.The child and parent versions of the SCARED have moderate parent-child agreement and good internal consistency, test-retest reliability, and discriminant validity; it is also sensitive to treatment response (Birmaher et al. 1999). The target population for this rating is 8-18 years of age (Birmaher et al. 1997). The parent and child version of the SCARED were administered before and after week 4 randomization. This measure is not validated for use in 4-7 year olds. (NCT01617083)
Timeframe: Before and after 4 week randomization
Intervention | units on a scale (Mean) | |
---|---|---|
Baseline | After 4 week randomization | |
Azithromycin | 31.82 | 30.88 |
Placebo | 20.43 | 21.97 |
4 trials available for prednisone and Chorea
Article | Year |
---|---|
Treatment of Sydenham's chorea with intravenous immunoglobulin, plasma exchange, or prednisone.
Topics: Adolescent; Child; Child, Preschool; Chorea; Female; Follow-Up Studies; Glucocorticoids; Humans; Imm | 2005 |
Randomized double-blind study with prednisone in Sydenham's chorea.
Topics: Adolescent; Anti-Bacterial Agents; Child; Chorea; Double-Blind Method; Drug Therapy, Combination; Fe | 2006 |
Serum lactic dehydrogenase and protein-bound hexose in rheumatic carditis and chorea--effect of corticosteroid therapy.
Topics: Blood Sedimentation; Child; Chorea; Clinical Trials as Topic; Female; Hexoses; Humans; L-Lactate Deh | 1974 |
Early ambulation in the treatment of acute rheumatic fever. A controlled study in children with acute rheumatic fever treated with prednisone.
Topics: Acute Disease; Blood Sedimentation; Body Temperature; Body Weight; Child; Chorea; Clinical Trials as | 1968 |
38 other studies available for prednisone and Chorea
Article | Year |
---|---|
Preliminary data on prednisone effectiveness in children with Sydenham chorea.
Topics: Anti-Inflammatory Agents; Child; Chorea; Drug Administration Schedule; Female; Humans; Induction Che | 2020 |
Chorea paralytica: a videotape case with rapid recovery and good long-term outcome.
Topics: Adolescent; Anti-Bacterial Agents; Antipsychotic Agents; Chorea; Female; Glucocorticoids; Haloperido | 2013 |
[Vasculitis as a reason of chronic headache].
Topics: Adolescent; Anemia, Hemolytic, Autoimmune; Chorea; Cyclophosphamide; Diagnosis, Differential; Drug T | 2008 |
[Acute poststreptoccocal chorea: an atypical postoperative reaction following cardiac surgery for mitral valvulopathy].
Topics: Acute Disease; Anti-Inflammatory Agents; Brain; C-Reactive Protein; Child; Chorea; Congo; Drug Thera | 2009 |
Chorea as an unusual presenting feature of anti-phospholipid syndrome.
Topics: Antiphospholipid Syndrome; Aspirin; Chorea; Diagnosis, Differential; Humans; Lupus Erythematosus, Sy | 2010 |
Chorea associated with thyrotoxicosis due to toxic multinodular goiter.
Topics: Antithyroid Agents; Atenolol; Chorea; Dibenzothiazepines; Female; Goiter, Nodular; Humans; Hyperthyr | 2011 |
Diffusion-weighted imaging in Sydenham's chorea.
Topics: Adolescent; Anti-Inflammatory Agents; Caudate Nucleus; Child; Chorea; Diffusion Magnetic Resonance I | 2013 |
[Treatment of chorea minor with prednisone and prednisone with chlorpromazine].
Topics: Child; Chlorpromazine; Chorea; Humans; Infant; Prednisone | 1956 |
[Treatment of chorea minor with prednisone and prednisone with chlorpromazine].
Topics: Child; Chlorpromazine; Chorea; Humans; Infant; Prednisone | 1956 |
[Treatment of chorea minor with prednisone and prednisone with chlorpromazine].
Topics: Child; Chlorpromazine; Chorea; Humans; Infant; Prednisone | 1956 |
[Treatment of chorea minor with prednisone and prednisone with chlorpromazine].
Topics: Child; Chlorpromazine; Chorea; Humans; Infant; Prednisone | 1956 |
[Prednisone in rheumatic diseases in childhood].
Topics: Arthritis; Arthritis, Rheumatoid; Child; Chorea; Humans; Infant; Prednisone; Rheumatic Diseases | 1956 |
[Prednisone in rheumatic diseases in childhood].
Topics: Arthritis; Arthritis, Rheumatoid; Child; Chorea; Humans; Infant; Prednisone; Rheumatic Diseases | 1956 |
[Prednisone in rheumatic diseases in childhood].
Topics: Arthritis; Arthritis, Rheumatoid; Child; Chorea; Humans; Infant; Prednisone; Rheumatic Diseases | 1956 |
[Prednisone in rheumatic diseases in childhood].
Topics: Arthritis; Arthritis, Rheumatoid; Child; Chorea; Humans; Infant; Prednisone; Rheumatic Diseases | 1956 |
DISSEMINATED LUPUS ERYTHEMATOSUS WITH SYDENHAM'S CHOREA: REPORT OF A CASE WITH A REVIEW OF THE LITERATURE.
Topics: Autoimmune Diseases; Barbiturates; Chorea; Humans; Lupus Erythematosus, Systemic; Methylprednisolone | 1963 |
[NEUROLOGIC COMPLICATIONS OF VIRAL HEPATITIS].
Topics: Adolescent; Athetosis; Chorea; Encephalitis; Hepatic Encephalopathy; Hepatitis; Hepatitis A; Humans; | 1964 |
[EFFECTS OF CORTICOTHERAPY ON THE SCHOLASTIC BEHAVIOR OF THE CHILD].
Topics: Adolescent; Arthritis; Arthritis, Juvenile; Cardiac Surgical Procedures; Child; Chorea; Humans; Lear | 1964 |
[ON A CASE OF CURED ACUTE CEREBRAL RHEUMATISM].
Topics: Child; Chorea; Drug Therapy; Humans; Prednisone; Rheumatic Diseases; Rheumatic Fever; Tranquilizing | 1965 |
Corticosteroid treatment in patients with Sydenham's chorea.
Topics: Administration, Oral; Child; Child, Preschool; Chorea; Drug Administration Schedule; Female; Glucoco | 2005 |
Corticosteroids in the treatment of acute Sydenham's chorea.
Topics: Chorea; Glucocorticoids; Humans; Outcome Assessment, Health Care; Prednisone | 2006 |
Resolution of arterial stenosis in a patient with periarterial neurocysticercosis treated with oral prednisone.
Topics: Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Child; Chorea; Gadoliniu | 2006 |
Rheumatic chorea: relationship to systemic manifestations and response to corticosteroids.
Topics: Adolescent; Adult; Child; Child, Preschool; Chorea; Female; Glucocorticoids; Humans; Male; Prednison | 2007 |
Chorea gravidarum associated with circulating lupus anticoagulant: successful outcome of pregnancy with prednisone and aspirin therapy. Case report.
Topics: Adult; Aspirin; Blood Coagulation Disorders; Blood Coagulation Factors; Chorea; Female; Humans; Infa | 1983 |
Lupus anticoagulant in pregnancy.
Topics: Aspirin; Blood Coagulation Disorders; Blood Coagulation Factors; Chorea; Drug Therapy, Combination; | 1984 |
Sydenham's chorea. A model for childhood autoimmune neuropsychiatric disorders.
Topics: Acute Disease; Adolescent; Autoimmune Diseases; Child; Child, Preschool; Chorea; Clinical Protocols; | 1994 |
Sydenham's chorea. A model for childhood autoimmune neuropsychiatric disorders.
Topics: Acute Disease; Adolescent; Autoimmune Diseases; Child; Child, Preschool; Chorea; Clinical Protocols; | 1994 |
Sydenham's chorea. A model for childhood autoimmune neuropsychiatric disorders.
Topics: Acute Disease; Adolescent; Autoimmune Diseases; Child; Child, Preschool; Chorea; Clinical Protocols; | 1994 |
Sydenham's chorea. A model for childhood autoimmune neuropsychiatric disorders.
Topics: Acute Disease; Adolescent; Autoimmune Diseases; Child; Child, Preschool; Chorea; Clinical Protocols; | 1994 |
Sydenham's chorea. A model for childhood autoimmune neuropsychiatric disorders.
Topics: Acute Disease; Adolescent; Autoimmune Diseases; Child; Child, Preschool; Chorea; Clinical Protocols; | 1994 |
Sydenham's chorea. A model for childhood autoimmune neuropsychiatric disorders.
Topics: Acute Disease; Adolescent; Autoimmune Diseases; Child; Child, Preschool; Chorea; Clinical Protocols; | 1994 |
Sydenham's chorea. A model for childhood autoimmune neuropsychiatric disorders.
Topics: Acute Disease; Adolescent; Autoimmune Diseases; Child; Child, Preschool; Chorea; Clinical Protocols; | 1994 |
Sydenham's chorea. A model for childhood autoimmune neuropsychiatric disorders.
Topics: Acute Disease; Adolescent; Autoimmune Diseases; Child; Child, Preschool; Chorea; Clinical Protocols; | 1994 |
Sydenham's chorea. A model for childhood autoimmune neuropsychiatric disorders.
Topics: Acute Disease; Adolescent; Autoimmune Diseases; Child; Child, Preschool; Chorea; Clinical Protocols; | 1994 |
[Rheumatic chorea: a still actual pathology?].
Topics: Adolescent; Child; Chorea; Female; Humans; Italy; Male; Penicillins; Prednisone; Rheumatic Diseases; | 1994 |
Reversible dementia and chorea in a young woman with the lupus anticoagulant.
Topics: Adult; Antiphospholipid Syndrome; Aspirin; Autoimmune Diseases; Chorea; Dementia; Depression; Diagno | 1996 |
Chorea in primary antiphospholipid syndrome.
Topics: Anti-Inflammatory Agents; Antibodies, Anticardiolipin; Antibodies, Antiphospholipid; Antiphospholipi | 1996 |
[Chorea gravidarum--case report].
Topics: Adult; Anti-Inflammatory Agents; Chorea; Diazepam; Female; Humans; Methylprednisolone Hemisuccinate; | 1996 |
Sydenham's chorea. Clinical and therapeutic update.
Topics: Basal Ganglia; Child; Chorea; Female; Humans; Immunoglobulins, Intravenous; Immunotherapy; Male; Obs | 1997 |
Successful treatment of steroid-resistant chorea associated with lupus by use of valproic acid and clonidine-HCL patch.
Topics: Administration, Oral; Adolescent; Chorea; Clonidine; Female; Humans; Injections, Intravenous; Lupus | 1997 |
Corticosteroids and chorea.
Topics: Adrenal Cortex Hormones; Chorea; Female; Humans; Huntington Disease; Middle Aged; Prednisone | 1979 |
Corticosteroids in the treatment of Sydenham's chorea.
Topics: Adolescent; Adrenocorticotropic Hormone; Adult; Child; Chorea; Drug Therapy, Combination; Female; Hu | 1978 |
Clinical features of chorea associated with systemic lupus erythematosus.
Topics: Adult; Azathioprine; Blood Sedimentation; Chlorpromazine; Chorea; Female; Haloperidol; Humans; Lupus | 1975 |
Steroid-responsive chorea in moyamoya disease.
Topics: Adolescent; Cerebral Angiography; Cerebral Revascularization; Chorea; Combined Modality Therapy; Dex | 1991 |
[Chorea and systemic lupus erythematosus].
Topics: Adolescent; Chorea; Drug Therapy, Combination; Female; Haloperidol; Humans; Lupus Erythematosus, Sys | 1990 |
[Acute chorea, systemic lupus erythematosus and antiphospholipid antibodies. Apropos of a case].
Topics: Acute Disease; Antibodies; Blood Coagulation Factors; Child; Chorea; Female; Humans; Lupus Erythemat | 1987 |
Diplopia. A rare manifestation of chorea.
Topics: Adolescent; Blood Sedimentation; Cardiomegaly; Child; Chorea; Diplopia; Female; Gait; Heart Ausculta | 1973 |
[Problems posed by the treatment of neurologic and neuropsychic manifestations of systemic lupus erythematosus].
Topics: Adult; Athetosis; Chorea; Diagnostic Errors; Epilepsy; Female; Humans; Immunosuppressive Agents; Lup | 1971 |
[Therapy of acute polyarthritis].
Topics: Age Factors; Analgesics; Antistreptolysin; Blood Sedimentation; Chorea; Humans; Lanatosides; Penicil | 1967 |
Some clinical observations on rheumatic fever in childhood. Patterns of the disease as seen in Southern iran.
Topics: Adolescent; Aspirin; Blood Sedimentation; Child; Child, Preschool; Chorea; Electrocardiography; Endo | 1971 |
Choreoathetosis in hyperthyroidism: a manifestation of a hyperadrenergic state.
Topics: Adult; Chorea; Female; Humans; Hyperthyroidism; Phenobarbital; Prednisone; Propranolol; Propylthiour | 1970 |
[Indication for corticotherapy in Sydenham's chorea].
Topics: Chorea; Humans; Prednisone | 1965 |