Page last updated: 2024-11-07

prednisone and Central Nervous System Lupus

prednisone has been researched along with Central Nervous System Lupus in 12 studies

Prednisone: A synthetic anti-inflammatory glucocorticoid derived from CORTISONE. It is biologically inert and converted to PREDNISOLONE in the liver.
prednisone : A synthetic glucocorticoid drug that is particularly effective as an immunosuppressant, and affects virtually all of the immune system. Prednisone is a prodrug that is converted by the liver into prednisolone (a beta-hydroxy group instead of the oxo group at position 11), which is the active drug and also a steroid.

Research Excerpts

ExcerptRelevanceReference
"Acute cerebellar ataxia is a rare primary manifestation of neuropsychiatric systemic lupus erythematosus (NPSLE)."2.72Cerebellar ataxia as a primary manifestation of neuropsychiatric systemic lupus erythematosus. ( Fernandez, MLL; Reyes, NGD; Sy, MCC; Zamora, GT, 2021)
"Prednisone treatment (3 mg/kg from 8 weeks of age) relieved the decrease of NAA but further increased the accumulation of pyruvate in the frontal cortex, additionally affected eight enriched pathways in the hypothalamus, and led to significant imbalances between the excitation and inhibition in both the frontal cortex and hypothalamus."1.56Analysis of brain metabolites by gas chromatography-mass spectrometry reveals the risk-benefit concerns of prednisone in MRL/lpr lupus mice. ( Li, S; Lu, F; Lu, H; Wang, S; Wen, C; Wu, D; Xie, M; Xie, Z; Xu, ZH; Zhou, J, 2020)
"Childhood-onset systemic lupus erythematosus (SLE) is a severe, lifelong, multisystem autoimmune disease."1.51Long-Term Clinical Outcomes in a Cohort of Adults With Childhood-Onset Systemic Lupus Erythematosus. ( Bijl, M; Bultink, IEM; de Leeuw, K; Dolhain, RJEM; Fritsch-Stork, R; Groot, N; Kamphuis, S; Shaikhani, D; Teng, YKO; Zirkzee, E, 2019)
"Objective Neuropsychiatric systemic lupus erythematosus (NPSLE) is a manifestation of systemic lupus erythematosus (SLE)."1.48Differences between central nervous system infection and neuropsychiatric systemic lupus erythematosus in patients with systemic lupus erythematosus. ( Fang, H; Lan, L; Lv, J; Qu, Y; Zhang, Q, 2018)
"Even with proper immunosuppressive treatment, SLE can relapse."1.37Lupus relapse presented as frosted branch retinal angiitis: case report. ( Arellanes-Garcia, L; Cornejo-Ballesteros, H; Hernandez-Da Mota, SE; Melgoza-del-Angel, C; Recillas-Gispert, C; Sanchez-Gonzalez, R; Teran-Estrada, L, 2011)
"Maintenance therapy of severe pediatric systemic lupus erythematosus (SLE) usually consists of azathioprine and prednisone ."1.35Experience with mycophenolate mofetil as maintenance therapy in five pediatric patients with severe systemic lupus erythematosus. ( Amann, K; Benz, K; Dittrich, K; Dötsch, J; Ross, S, 2009)

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's6 (50.00)29.6817
2010's4 (33.33)24.3611
2020's2 (16.67)2.80

Authors

AuthorsStudies
Zhou, J2
Lu, F2
Li, S2
Xie, M2
Lu, H2
Xie, Z1
Wu, D1
Wang, S2
Wen, C2
Xu, ZH1
Sy, MCC1
Reyes, NGD1
Zamora, GT1
Fernandez, MLL1
Fang, H1
Lan, L1
Qu, Y1
Zhang, Q1
Lv, J1
Groot, N1
Shaikhani, D1
Teng, YKO1
de Leeuw, K1
Bijl, M1
Dolhain, RJEM1
Zirkzee, E1
Fritsch-Stork, R1
Bultink, IEM1
Kamphuis, S1
Zu, Y1
Yu, J1
Ruan, Y1
Xu, Z1
Ataia, I1
Casaulta, C1
von Vigier, RO1
Pfammatter, JP1
Brekenfeld, C1
Sauvain, MJ1
Steinlin, M1
Bhagavati, S1
Choi, J1
Descloux, E1
Durieu, I1
Cochat, P1
Vital-Durand, D1
Ninet, J1
Fabien, N1
Cimaz, R1
Geara, AS1
Torbey, E1
El-imad, B1
Dittrich, K1
Ross, S1
Benz, K1
Amann, K1
Dötsch, J1
Hernandez-Da Mota, SE1
Arellanes-Garcia, L1
Recillas-Gispert, C1
Cornejo-Ballesteros, H1
Melgoza-del-Angel, C1
Teran-Estrada, L1
Sanchez-Gonzalez, R1
Olfat, MO1
Al-Mayouf, SM1
Muzaffer, MA1

Reviews

1 review available for prednisone and Central Nervous System Lupus

ArticleYear
Cerebellar ataxia as a primary manifestation of neuropsychiatric systemic lupus erythematosus.
    BMJ case reports, 2021, Feb-04, Volume: 14, Issue:2

    Topics: Adult; Anti-Inflammatory Agents; Antimalarials; Cerebellar Ataxia; Female; Gait Analysis; Headache;

2021

Other Studies

11 other studies available for prednisone and Central Nervous System Lupus

ArticleYear
Analysis of brain metabolites by gas chromatography-mass spectrometry reveals the risk-benefit concerns of prednisone in MRL/lpr lupus mice.
    Inflammopharmacology, 2020, Volume: 28, Issue:2

    Topics: Animals; Brain; Disease Models, Animal; Female; Gas Chromatography-Mass Spectrometry; Glucocorticoid

2020
Differences between central nervous system infection and neuropsychiatric systemic lupus erythematosus in patients with systemic lupus erythematosus.
    The Journal of international medical research, 2018, Volume: 46, Issue:1

    Topics: Adult; Anti-Inflammatory Agents; Blood Glucose; C-Reactive Protein; Central Nervous System Infection

2018
Long-Term Clinical Outcomes in a Cohort of Adults With Childhood-Onset Systemic Lupus Erythematosus.
    Arthritis & rheumatology (Hoboken, N.J.), 2019, Volume: 71, Issue:2

    Topics: Adolescent; Adult; Age of Onset; Aged; Antibodies, Antiphospholipid; Antirheumatic Agents; Child; Ch

2019
Limited preventive effect of prednisone on neuropsychiatric symptoms in murine systemic lupus erythematosus.
    Inflammopharmacology, 2019, Volume: 27, Issue:3

    Topics: Animals; Brain; Cardiolipins; Depression; Disease Models, Animal; Female; Glucocorticoids; Lupus Vas

2019
[Vasculitis as a reason of chronic headache].
    Praxis, 2008, Mar-19, Volume: 97, Issue:6

    Topics: Adolescent; Anemia, Hemolytic, Autoimmune; Chorea; Cyclophosphamide; Diagnosis, Differential; Drug T

2008
Reversible basal ganglia and amygdala lesions in central nervous system lupus.
    The Journal of rheumatology, 2008, Volume: 35, Issue:12

    Topics: Adolescent; Amygdala; Antirheumatic Agents; Basal Ganglia; Female; Humans; Lupus Vasculitis, Central

2008
Influence of age at disease onset in the outcome of paediatric systemic lupus erythematosus.
    Rheumatology (Oxford, England), 2009, Volume: 48, Issue:7

    Topics: Adolescent; Age of Onset; Cause of Death; Child; Female; Humans; Immunosuppressive Agents; Kaplan-Me

2009
Lupus cerebritis after visiting a tanning salon.
    Bulletin of the NYU hospital for joint diseases, 2009, Volume: 67, Issue:4

    Topics: Antibodies, Antinuclear; Anticonvulsants; Beauty Culture; Female; Headache; Humans; Immunosuppressiv

2009
Experience with mycophenolate mofetil as maintenance therapy in five pediatric patients with severe systemic lupus erythematosus.
    Klinische Padiatrie, 2009, Volume: 221, Issue:7

    Topics: Adolescent; Azathioprine; Child; Disease Progression; Dose-Response Relationship, Drug; Drug Therapy

2009
Lupus relapse presented as frosted branch retinal angiitis: case report.
    Ocular immunology and inflammation, 2011, Volume: 19, Issue:5

    Topics: Adolescent; Azathioprine; Female; Humans; Immunosuppressive Agents; Lupus Vasculitis, Central Nervou

2011
Pattern of neuropsychiatric manifestations and outcome in juvenile systemic lupus erythematosus.
    Clinical rheumatology, 2004, Volume: 23, Issue:5

    Topics: Adolescent; Cerebrovascular Disorders; Child; Child, Preschool; Disease-Free Survival; Electroenceph

2004