Page last updated: 2024-11-07

prednisone and Cardiomyopathy, Dilated

prednisone has been researched along with Cardiomyopathy, Dilated in 29 studies

Prednisone: A synthetic anti-inflammatory glucocorticoid derived from CORTISONE. It is biologically inert and converted to PREDNISOLONE in the liver.
prednisone : A synthetic glucocorticoid drug that is particularly effective as an immunosuppressant, and affects virtually all of the immune system. Prednisone is a prodrug that is converted by the liver into prednisolone (a beta-hydroxy group instead of the oxo group at position 11), which is the active drug and also a steroid.

Cardiomyopathy, Dilated: A form of CARDIAC MUSCLE disease that is characterized by ventricular dilation, VENTRICULAR DYSFUNCTION, and HEART FAILURE. Risk factors include SMOKING; ALCOHOL DRINKING; HYPERTENSION; INFECTION; PREGNANCY; and mutations in the LMNA gene encoding LAMIN TYPE A, a NUCLEAR LAMINA protein.

Research Excerpts

ExcerptRelevanceReference
"Fifty-two patients with recently diagnosed idiopathic dilated cardiomyopathy were studied to determine the incidence of myocarditis; patients were randomly assigned to receive either conventional therapy alone or conventional therapy plus prednisone to assess possible therapeutic efficacy with regard to survival."9.06Recently diagnosed idiopathic dilated cardiomyopathy: incidence of myocarditis and efficacy of prednisone therapy. ( Latham, RD; Moody, JM; Mulrow, JP; Robinowitz, M; Virmani, R, 1989)
"Fifty-two patients with recently diagnosed idiopathic dilated cardiomyopathy were studied to determine the incidence of myocarditis; patients were randomly assigned to receive either conventional therapy alone or conventional therapy plus prednisone to assess possible therapeutic efficacy with regard to survival."5.06Recently diagnosed idiopathic dilated cardiomyopathy: incidence of myocarditis and efficacy of prednisone therapy. ( Latham, RD; Moody, JM; Mulrow, JP; Robinowitz, M; Virmani, R, 1989)
"The immunosuppressive therapy with azathioprine or cyclosporine plus prednisone leads to decrease of active myocarditis intensity in a higher proportion of cases than the treatment with only prednisone or no immunosuppressive drugs."3.68[Histologic response of the myocardium to various immunosuppressor schedules in patients with dilated cardiomyopathy and diagnosis of myocarditis at endomyocardial biopsy]. ( Aiello, VD; Camargo, PR; Ebaid, M; Fiorelli, A; Higuchi, Mde L; Mazzieri, R; Pileggi, F; Snitcowsky, R, 1990)
"Thirty-four patients with history of congestive heart failure, dilated cardiomyopathy, and biopsy-proven lymphocytic myocarditis were treated for six months with immunosuppressive agents (prednisone and azathioprine) in addition to standard therapy for congestive heart failure."3.67Lymphocytic myocarditis and dilated cardiomyopathy: treatment with immunosuppressive agents. ( Badhwar, K; Bott-Silverman, C; Hobbs, RE; Pelegrin, D; Ratliff, NB; Rincon, G; Sterba, R, 1989)
"Of 202 patients with dilated cardiomyopathy, 84 patients with increased HLA expression were randomized to receive either immunosuppression or placebo for 3 months; they were then followed for 2 years."2.70Randomized, placebo-controlled study for immunosuppressive treatment of inflammatory dilated cardiomyopathy: two-year follow-up results. ( Glanowska, G; Niklewski, T; Nowalany-Kozielska, E; Polonski, L; Rozek, MM; Wilczewski, P; Wodniecki, J; Wojciechowska, C; Wojnicz, R; Zembala, M, 2001)
"These data suggest that patients with idiopathic dilated cardiomyopathy may have some improvement when given a high dose of prednisone daily."2.66A prospective, randomized, controlled trial of prednisone for dilated cardiomyopathy. ( Alling, D; Brenner, M; Cannon, RO; Cunnion, RE; Epstein, SE; Palmeri, ST; Parker, MM; Parrillo, JE; Schaer, GL; Suffredini, AF, 1989)
"Diagnosis of inflammatory dilated cardiomyopathy relies on the histological and immunohistological examination of endomyocardial biopsies."2.40[Therapy of dilated cardiomyopathies with and without inflammation]. ( Hufnagel, G; Maisch, B; Pankuweit, S, 1998)
"114 patients with newly diagnosed dilated cardiomyopathy were divided into three groups, according to the histological pattern: group A, acute myocarditis; group B, borderline myocarditis; and group C, non-inflammatory cardiomyopathy."1.32Long term follow up of children with myocarditis treated by immunosuppression and of children with dilated cardiomyopathy. ( Bassano, C; Bevilacqua, M; Boldrini, R; Bottazzo, GF; Camassei, FD; Fierabracci, A; Gagliardi, MG; Leonardi, B; Ugazio, AG, 2004)

Research

Studies (29)

TimeframeStudies, this research(%)All Research%
pre-19908 (27.59)18.7374
1990's10 (34.48)18.2507
2000's5 (17.24)29.6817
2010's5 (17.24)24.3611
2020's1 (3.45)2.80

Authors

AuthorsStudies
Serrano, OK1
Kutzler, HL1
Rochon, C1
Radojevic, JA1
Lawlor, MT1
Hammond, JA1
Gluck, J1
Feingold, AD1
Jaiswal, A1
Padberg, S1
Mick, I1
Frenzel, C1
Greil, R1
Hilberath, J1
Schaefer, C1
Schiavon, F1
Cuffaro, S1
Ometto, F1
Mojoli, M1
Ramonda, R1
Lee, HJ1
Sul, H1
Kim, HW1
Lyu, YS1
Park, CY1
Hong, R1
Park, SG1
Ross, JJ1
Britton, KA1
Desai, AS1
Stevenson, WG1
Kochbati, L1
Fdhila, F1
Belaid, I1
Rifi, H1
Barsaoui, S1
Ben Romdhane, N1
Bel Hadj Ali, Z1
Mezlini, A1
Oubich, F1
Maalej, M1
Hia, CP1
Yip, WC1
Tai, BC1
Quek, SC1
Gagliardi, MG1
Bevilacqua, M1
Bassano, C1
Leonardi, B1
Boldrini, R1
Camassei, FD1
Fierabracci, A1
Ugazio, AG1
Bottazzo, GF1
Beitzke, A1
Suppan, C1
Trittenwein, G1
Cunnion, RE2
Parrillo, JE2
Rubio, JA1
Pulpón, LA1
Cavero, MA1
Oteo, JF1
Maicas, C1
Silva, L1
Serrano-Fiz, S1
Burgos, R1
Artaza, M1
Téllez, G1
Söylemezoğlu, O1
Beşbaş, N1
Ozkutlu, S1
Saatçi, U1
Olszowska, M1
Tracz, W1
Kokoszka, M1
Pieniazek, P1
Przewłocki, T1
Hlawaty, M1
Podolec, P1
Frasik, W1
Lazar, A1
Dziatkowiak, A1
Hufnagel, G1
Pankuweit, S1
Maisch, B1
Frustaci, A1
Chimenti, C1
Maseri, A1
Jimenez, J1
Young, JB1
Wojnicz, R1
Nowalany-Kozielska, E1
Wojciechowska, C1
Glanowska, G1
Wilczewski, P1
Niklewski, T1
Zembala, M1
Polonski, L1
Rozek, MM1
Wodniecki, J1
Subhash, HS1
George, P1
Sowmya, G1
George, B1
Ashwin, I1
Cherian, AM1
Desjardins, V1
Pelletier, G1
Leung, TK1
Waters, D1
Arteaga-Fernánez, E1
Barretto, AC1
Mady, C1
Higuchi, ML1
Fiorelli, AI1
Bellotti, G1
Jatene, AD1
Pileggi, F2
Higuchi, Mde L1
Camargo, PR1
Aiello, VD1
Mazzieri, R1
Snitcowsky, R1
Fiorelli, A1
Ebaid, M1
Midei, MG1
DeMent, SH1
Feldman, AM1
Hutchins, GM1
Baughman, KL1
Epstein, SE1
Parker, MM1
Suffredini, AF1
Brenner, M1
Schaer, GL1
Palmeri, ST1
Cannon, RO1
Alling, D1
Christen, R1
Morant, R1
Schneider, J1
Jenni, R1
Fehr, J1
O'Connell, JB1
Hobbs, RE1
Pelegrin, D1
Ratliff, NB1
Bott-Silverman, C1
Rincon, G1
Sterba, R1
Badhwar, K1
Latham, RD1
Mulrow, JP1
Virmani, R1
Robinowitz, M1
Moody, JM1
Leroy, O1
Asseman, P1
Traisnel, G1
Durand, P1
Beuscart, R1
Dewilde, A1
Wattré, P1
Théry, C1
Amuchástegui, M1
Madoery, R1
Noguera, E1
Mothe, G1
Amuchástegui, LM1

Clinical Trials (3)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
RANDOMIZED, MULTICENTRIC STUDY COMPARING THE EFFECT OF TWO REGIMENS OF COMBINED IMMUNOSUPPRESSIVE THERAPY IN THE TREATMENT OF INFLAMMATORY CARDIOMYOPATHY CZECH-ICIT (CZECH INFLAMMATORY CARDIOMYOPATHY IMMUNOSUPPRESSION TRIAL)[NCT01877746]Phase 3234 participants (Anticipated)Interventional2013-01-31Recruiting
Myocarditis Causing Premature Ventricular Contractions:Insights From the MAVERIC Registry[NCT05158751]100 participants (Anticipated)Observational2023-01-31Not yet recruiting
Evaluation of Patients With Critical Illness: Intensive Care Training Protocol[NCT00100217]1 participants (Actual)Observational2004-12-21Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

3 reviews available for prednisone and Cardiomyopathy, Dilated

ArticleYear
Immunosuppressive therapy in acute myocarditis: an 18 year systematic review.
    Archives of disease in childhood, 2004, Volume: 89, Issue:6

    Topics: Acute Disease; Adolescent; Azathioprine; Cardiomyopathy, Dilated; Child; Child, Preschool; Female; H

2004
[A heart transplant in a patient with doxorubicin-induced myocardiopathy as a complication of the treatment of a lymphoma].
    Revista espanola de cardiologia, 1994, Volume: 47, Issue:11

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Cardiomyopathy, Dilated; Cyclophosphamide; Da

1994
[Therapy of dilated cardiomyopathies with and without inflammation].
    Medizinische Klinik (Munich, Germany : 1983), 1998, Apr-15, Volume: 93, Issue:4

    Topics: Adjuvants, Immunologic; Adolescent; Adult; Angiotensin-Converting Enzyme Inhibitors; Anti-Inflammato

1998

Trials

3 trials available for prednisone and Cardiomyopathy, Dilated

ArticleYear
Randomized, placebo-controlled study for immunosuppressive treatment of inflammatory dilated cardiomyopathy: two-year follow-up results.
    Circulation, 2001, Jul-03, Volume: 104, Issue:1

    Topics: Adult; Azathioprine; Biopsy; Cardiomyopathy, Dilated; Chronic Disease; Drug Therapy, Combination; En

2001
Randomized, placebo-controlled study for immunosuppressive treatment of inflammatory dilated cardiomyopathy: two-year follow-up results.
    Circulation, 2001, Jul-03, Volume: 104, Issue:1

    Topics: Adult; Azathioprine; Biopsy; Cardiomyopathy, Dilated; Chronic Disease; Drug Therapy, Combination; En

2001
Randomized, placebo-controlled study for immunosuppressive treatment of inflammatory dilated cardiomyopathy: two-year follow-up results.
    Circulation, 2001, Jul-03, Volume: 104, Issue:1

    Topics: Adult; Azathioprine; Biopsy; Cardiomyopathy, Dilated; Chronic Disease; Drug Therapy, Combination; En

2001
Randomized, placebo-controlled study for immunosuppressive treatment of inflammatory dilated cardiomyopathy: two-year follow-up results.
    Circulation, 2001, Jul-03, Volume: 104, Issue:1

    Topics: Adult; Azathioprine; Biopsy; Cardiomyopathy, Dilated; Chronic Disease; Drug Therapy, Combination; En

2001
A prospective, randomized, controlled trial of prednisone for dilated cardiomyopathy.
    The New England journal of medicine, 1989, Oct-19, Volume: 321, Issue:16

    Topics: Cardiomyopathy, Dilated; Drug Administration Schedule; Fibroblasts; Follow-Up Studies; Humans; Lymph

1989
Recently diagnosed idiopathic dilated cardiomyopathy: incidence of myocarditis and efficacy of prednisone therapy.
    American heart journal, 1989, Volume: 117, Issue:4

    Topics: Adult; Cardiomyopathy, Dilated; Female; Humans; Male; Middle Aged; Myocarditis; Myocardium; Predniso

1989

Other Studies

23 other studies available for prednisone and Cardiomyopathy, Dilated

ArticleYear
Incidental COVID-19 in a heart-kidney transplant recipient with malnutrition and recurrent infections: Implications for the SARS-CoV-2 immune response.
    Transplant infectious disease : an official journal of the Transplantation Society, 2020, Volume: 22, Issue:6

    Topics: Antibiotics, Antineoplastic; Bacteremia; BK Virus; Cardiomyopathy, Dilated; Cardiotoxicity; COVID-19

2020
Transient congenital dilated cardiomyopathy after maternal R-CHOP chemotherapy during pregnancy.
    Reproductive toxicology (Elmsford, N.Y.), 2017, Volume: 71

    Topics: Adult; Antibodies, Monoclonal, Murine-Derived; Antineoplastic Combined Chemotherapy Protocols; Cardi

2017
Takayasu arteritis and NYHA III/IV idiopathic cardiomiopathy: tocilizumab proves effective and safe.
    Joint bone spine, 2014, Volume: 81, Issue:3

    Topics: Adolescent; Anti-Inflammatory Agents; Antibodies, Monoclonal, Humanized; Cardiomyopathy, Dilated; Fe

2014
IgG4-related systemic disease presenting with pleural effusion, ascites and dilated cardiomyopathy.
    Tumori, 2016, Nov-11, Volume: 102, Issue:Suppl. 2

    Topics: Adult; Ascites; Biopsy; Cardiomyopathy, Dilated; Electrocardiography; Humans; Immunoglobulin G; Lymp

2016
Interactive medical case. The beat goes on.
    The New England journal of medicine, 2010, Apr-15, Volume: 362, Issue:15

    Topics: Adult; Amiodarone; Anti-Arrhythmia Agents; Biopsy; Bundle-Branch Block; Cardiomyopathy, Dilated; Def

2010
[Pediatric Hodgkin disease in North Tunisia: clinical and therapeutic study].
    Cancer radiotherapie : journal de la Societe francaise de radiotherapie oncologique, 2012, Volume: 16, Issue:7

    Topics: Adolescent; Anemia, Aplastic; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cardiomyopa

2012
Long term follow up of children with myocarditis treated by immunosuppression and of children with dilated cardiomyopathy.
    Heart (British Cardiac Society), 2004, Volume: 90, Issue:10

    Topics: Analysis of Variance; Biopsy; Cardiomyopathy, Dilated; Child, Preschool; Cyclosporine; Endocardium;

2004
[Immunosuppressive therapy in congestive cardiomyopathy in childhood].
    Monatsschrift Kinderheilkunde : Organ der Deutschen Gesellschaft fur Kinderheilkunde, 1984, Volume: 132, Issue:2

    Topics: Adolescent; Autoantibodies; Autoimmune Diseases; Azathioprine; Cardiomyopathy, Dilated; Child; Elect

1984
Immunosuppressive therapy for myocarditis.
    The New England journal of medicine, 1995, Dec-21, Volume: 333, Issue:25

    Topics: Anti-Inflammatory Agents; Cardiomyopathy, Dilated; Humans; Immunosuppressive Agents; Myocarditis; Pr

1995
Dilated cardiomyopathy in juvenile chronic arthritis.
    Scandinavian journal of rheumatology, 1994, Volume: 23, Issue:3

    Topics: Arthritis, Juvenile; Cardiomyopathy, Dilated; Child; Digitalis; Echocardiography; Humans; Male; Meth

1994
[Long-term observation of patients with biopsy proven myocarditis or dilated cardiomyopathy].
    Przeglad lekarski, 1996, Volume: 53, Issue:10

    Topics: Adolescent; Adult; Azathioprine; Biopsy; Cardiomyopathy, Dilated; Drug Therapy, Combination; Echocar

1996
Global biventricular dysfunction in patients with asymptomatic coronary artery disease may be caused by myocarditis.
    Circulation, 1999, Mar-16, Volume: 99, Issue:10

    Topics: Adult; Angiotensin-Converting Enzyme Inhibitors; Autoimmune Diseases; Azathioprine; Biopsy; Cardiomy

1999
Clinical challenges in thoracic organ transplantation: case studies in immunosuppressive therapy.
    The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation, 2000, Volume: 19, Issue:7

    Topics: Adult; Biopsy; Cardiomyopathy, Dilated; Cyclosporine; Drug Administration Routes; Drug Therapy, Comb

2000
Progressive dilated cardiomyopathy in a patient with hypereosinophilic syndrome despite prednisone induced hematological remission.
    The Journal of the Association of Physicians of India, 2001, Volume: 49

    Topics: Adolescent; Cardiomyopathy, Dilated; Disease Progression; Echocardiography; Follow-Up Studies; Human

2001
Successful treatment of severe heart failure caused by idiopathic giant cell myocarditis.
    The Canadian journal of cardiology, 1992, Volume: 8, Issue:8

    Topics: Autoimmune Diseases; Azathioprine; Biopsy; Cardiomyopathy, Dilated; Cyclosporine; Drug Therapy, Comb

1992
[Lymphocytic myocarditis. Response to treatment with immunosuppressive drugs].
    Arquivos brasileiros de cardiologia, 1990, Volume: 55, Issue:3

    Topics: Adolescent; Adult; Azathioprine; Cardiomyopathy, Dilated; Female; Follow-Up Studies; Humans; Lymphoc

1990
[Histologic response of the myocardium to various immunosuppressor schedules in patients with dilated cardiomyopathy and diagnosis of myocarditis at endomyocardial biopsy].
    Arquivos brasileiros de cardiologia, 1990, Volume: 54, Issue:5

    Topics: Adolescent; Azathioprine; Cardiomyopathy, Dilated; Child; Child, Preschool; Cyclosporins; Drug Thera

1990
Peripartum myocarditis and cardiomyopathy.
    Circulation, 1990, Volume: 81, Issue:3

    Topics: Adult; Azathioprine; Cardiomyopathy, Dilated; Female; Humans; Immunosuppression Therapy; Myocarditis

1990
Progressive dilated cardiomyopathy in a patient with longstanding and complete prednisone-induced hematological remission of idiopathic hypereosinophilic syndrome.
    Klinische Wochenschrift, 1989, Mar-15, Volume: 67, Issue:6

    Topics: Adult; Biopsy; Cardiomyopathy, Dilated; Endocardium; Endomyocardial Fibrosis; Eosinophilia; Eosinoph

1989
Immunosuppression for dilated cardiomyopathy.
    The New England journal of medicine, 1989, Oct-19, Volume: 321, Issue:16

    Topics: Cardiomyopathy, Dilated; Humans; Immunosuppression Therapy; Prednisone

1989
Lymphocytic myocarditis and dilated cardiomyopathy: treatment with immunosuppressive agents.
    Cleveland Clinic journal of medicine, 1989, Volume: 56, Issue:6

    Topics: Adult; Aged; Azathioprine; Cardiomyopathy, Dilated; Female; Humans; Male; Middle Aged; Myocarditis;

1989
[Anti-Coxsackie antibodies and congestive cardiomyopathies].
    Archives des maladies du coeur et des vaisseaux, 1986, Volume: 79, Issue:10

    Topics: Adult; Antibodies, Viral; Azathioprine; Cardiomyopathy, Dilated; Coxsackievirus Infections; Enterovi

1986
[Cardiac scintigraphy with gallium 67: an alternative in the treatment of dilated cardiomyopathy].
    Medicina, 1987, Volume: 47, Issue:3

    Topics: Adult; Azathioprine; Cardiomyopathy, Dilated; Echocardiography; Gallium Radioisotopes; Humans; Male;

1987