Page last updated: 2024-11-07

prednisone and Bronchial Hyperreactivity

prednisone has been researched along with Bronchial Hyperreactivity in 9 studies

Prednisone: A synthetic anti-inflammatory glucocorticoid derived from CORTISONE. It is biologically inert and converted to PREDNISOLONE in the liver.
prednisone : A synthetic glucocorticoid drug that is particularly effective as an immunosuppressant, and affects virtually all of the immune system. Prednisone is a prodrug that is converted by the liver into prednisolone (a beta-hydroxy group instead of the oxo group at position 11), which is the active drug and also a steroid.

Bronchial Hyperreactivity: Tendency of the smooth muscle of the tracheobronchial tree to contract more intensely in response to a given stimulus than it does in the response seen in normal individuals. This condition is present in virtually all symptomatic patients with asthma. The most prominent manifestation of this smooth muscle contraction is a decrease in airway caliber that can be readily measured in the pulmonary function laboratory.

Research Excerpts

ExcerptRelevanceReference
" After each period, dose-response curves were measured on 4 study days with doubling doses of salbutamol, ipratropium, a combination of salbutamol and ipratropium, and placebo until a plateau in FEV1 was reached."2.67Separate and combined effects of corticosteroids and bronchodilators on airflow obstruction and airway hyperresponsiveness in asthma. ( Alting-Hebing, D; Breederveld, N; Koëter, GH; Postma, DS; van der Mark, TW; Wempe, JB, 1992)
"Aspecific bronchial hyperreactivity was found in 6 (20."1.29Aspecific bronchial hyperreactivity in pulmonary sarcoidosis. ( Ledda, MA; Marcias, S; Perra, R; Rosetti, L; Severino, C, 1994)

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's5 (55.56)18.2507
2000's3 (33.33)29.6817
2010's1 (11.11)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Clarke, DL1
Davis, NH1
Majithiya, JB1
Piper, SC1
Lewis, A1
Sleeman, MA1
Corkill, DJ1
May, RD1
Weng, JL1
Zheng, YS1
Ma, QF1
Pijnenburg, MW1
Bakker, EM1
Hop, WC1
De Jongste, JC1
Slats, AM1
Sont, JK1
van Klink, RH1
Bel, EH1
Sterk, PJ1
Marcias, S1
Ledda, MA1
Perra, R1
Severino, C1
Rosetti, L1
Wong, AG1
Pavord, ID1
Sears, MR1
Hargreave, FE1
Edell, D2
Bruce, E1
Hale, K1
Khoshoo, V1
Zaragoza, RH1
Szefler, SJ1
Bratton, DL1
Wempe, JB1
Postma, DS1
Breederveld, N1
Alting-Hebing, D1
van der Mark, TW1
Koëter, GH1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Prospective, Open Label, Single-center Study of the Long-term Prognosis of Moderate to Severe Bronchial Hyperresponsiveness (BHR) in Asthmatic Preschool Children.[NCT01144910]0 participants (Actual)Observational2011-05-31Withdrawn (stopped due to Due to few capacities 2011 to 2016 the study was withdrawn.)
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

4 trials available for prednisone and Bronchial Hyperreactivity

ArticleYear
[The long term effect of small dose budesonide turbuhaler on mild bronchial asthma].
    Zhonghua jie he he hu xi za zhi = Zhonghua jiehe he huxi zazhi = Chinese journal of tuberculosis and respiratory diseases, 2005, Volume: 28, Issue:2

    Topics: Administration, Inhalation; Adolescent; Adult; Airway Resistance; Anti-Asthmatic Agents; Asthma; Bro

2005
Titrating steroids on exhaled nitric oxide in children with asthma: a randomized controlled trial.
    American journal of respiratory and critical care medicine, 2005, Oct-01, Volume: 172, Issue:7

    Topics: Adolescent; Anti-Inflammatory Agents; Asthma; Breath Tests; Bronchial Hyperreactivity; Budesonide; C

2005
Improvement in bronchodilation following deep inspiration after a course of high-dose oral prednisone in asthma.
    Chest, 2006, Volume: 130, Issue:1

    Topics: Administration, Oral; Adult; Airway Obstruction; Anti-Inflammatory Agents; Asthma; Breath Tests; Bro

2006
Separate and combined effects of corticosteroids and bronchodilators on airflow obstruction and airway hyperresponsiveness in asthma.
    The Journal of allergy and clinical immunology, 1992, Volume: 89, Issue:3

    Topics: Adrenal Cortex Hormones; Adult; Airway Obstruction; Airway Resistance; Albuterol; Asthma; Bronchial

1992

Other Studies

5 other studies available for prednisone and Bronchial Hyperreactivity

ArticleYear
Development of a mouse model mimicking key aspects of a viral asthma exacerbation.
    Clinical science (London, England : 1979), 2014, Volume: 126, Issue:8

    Topics: Animals; Asthma; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; CD4-Positive T-Lymphocytes

2014
Aspecific bronchial hyperreactivity in pulmonary sarcoidosis.
    Sarcoidosis, 1994, Volume: 11, Issue:2

    Topics: Adult; Asthma; Bronchial Hyperreactivity; Bronchial Provocation Tests; Female; Forced Expiratory Vol

1994
A case for serial examination of sputum inflammatory cells.
    The European respiratory journal, 1996, Volume: 9, Issue:10

    Topics: Anti-Infective Agents; Anti-Inflammatory Agents; Asthma; Bronchial Hyperreactivity; Bronchitis; Bude

1996
Reduced long-term respiratory morbidity after treatment of respiratory syncytial virus bronchiolitis with ribavirin in previously healthy infants: a preliminary report.
    Pediatric pulmonology, 1998, Volume: 25, Issue:3

    Topics: Albuterol; Antiviral Agents; Asthma; Bronchial Hyperreactivity; Bronchiolitis; Bronchodilator Agents

1998
Brief report: therapeutic manipulations in severe nocturnal asthma. A nonconventional approach in a severe high-risk asthmatic.
    The Journal of asthma : official journal of the Association for the Care of Asthma, 1992, Volume: 29, Issue:4

    Topics: Adolescent; Asthma; Bronchial Hyperreactivity; Bronchodilator Agents; Combined Modality Therapy; Hum

1992