Page last updated: 2024-11-07

prednisone and Brain Edema

prednisone has been researched along with Brain Edema in 27 studies

Prednisone: A synthetic anti-inflammatory glucocorticoid derived from CORTISONE. It is biologically inert and converted to PREDNISOLONE in the liver.
prednisone : A synthetic glucocorticoid drug that is particularly effective as an immunosuppressant, and affects virtually all of the immune system. Prednisone is a prodrug that is converted by the liver into prednisolone (a beta-hydroxy group instead of the oxo group at position 11), which is the active drug and also a steroid.

Brain Edema: Increased intracellular or extracellular fluid in brain tissue. Cytotoxic brain edema (swelling due to increased intracellular fluid) is indicative of a disturbance in cell metabolism, and is commonly associated with hypoxic or ischemic injuries (see HYPOXIA, BRAIN). An increase in extracellular fluid may be caused by increased brain capillary permeability (vasogenic edema), an osmotic gradient, local blockages in interstitial fluid pathways, or by obstruction of CSF flow (e.g., obstructive HYDROCEPHALUS). (From Childs Nerv Syst 1992 Sep; 8(6):301-6)

Research Excerpts

ExcerptRelevanceReference
"Methyprednisone was administrated and the symptoms relieved gradually."2.82Predominant cerebral cytokine release syndrome in CD19-directed chimeric antigen receptor-modified T cell therapy. ( Cui, Q; Hu, Y; Huang, H; Jin, A; Liang, B; Luo, Y; Pu, C; Shi, J; Sun, J; Wu, Z; Xiao, L; Yu, J, 2016)
"He had multiple prior episodes of cryptococcal meningitis with complications necessitating ventriculoperitoneal shunt placement and was on suppressive fluconazole when he developed worsening brain manifestations."1.56Case Report: A Case of Severe Cryptococcal Immune Reconstitution Inflammatory Syndrome Presenting with Brain and Intradural Abscesses in an HIV Patient. ( Jeng, A; Kalinoski, T; Malenfant, J; Yim, C, 2020)
"Neurosarcoidosis is rare and difficult to diagnose especially in the absence of systemic involvement."1.35Neurosarcoidosis--the great mimicker. ( Ajjan, M; Grigorian, AA; Walid, MS, 2008)
"Cysticercosis is an helminthic disease which is usually observed in endemic areas or in immigrants coming from these areas."1.32[Neurocysticercosis complicating the treatment of cutaneous cysticercosis in a traveller]. ( Bricaire, E; Caumes, E; Chemali, N; Danis, M; Epelboin, L; Klement, E, 2004)
" The latency period between the steroid therapy and the occurrence of AON ranged from 12 to 60 months; steroid therapy lasted for 12 to 16 days with a total dosage equivalent to 2370-7180 mg prednisolone."1.28[Craniocerebral trauma and aseptic osteonecrosis. Steroid-induced sequelae after therapy of brain edema]. ( Griss, P; Pfeiffer, M, 1992)
"In an 18-month period seven children who were treated for a variety of neurological and non-neurological diseases, and in whom the corticosteroid or corticotrophin dosage was reduced, developed a syndrome indistinguishable from "benign intracranial hypertension."1.25Benign intracranial hypertension following corticosteroid withdrawal in childhood. ( Neville, BG; Wilson, J, 1970)

Research

Studies (27)

TimeframeStudies, this research(%)All Research%
pre-199013 (48.15)18.7374
1990's2 (7.41)18.2507
2000's5 (18.52)29.6817
2010's5 (18.52)24.3611
2020's2 (7.41)2.80

Authors

AuthorsStudies
Kalinoski, T1
Malenfant, J1
Yim, C1
Jeng, A1
Kadono, Y1
Nakamura, Y1
Ogawa, Y1
Yamamoto, S1
Kajikawa, R1
Nakajima, Y1
Matsumoto, M1
Kishima, H1
Alp, A1
Akdam, H1
Akar, H1
Koseoglu, K1
Ozkul, A1
Meteoglu, I1
Yenicerioglu, Y1
Hu, Y1
Sun, J1
Wu, Z1
Yu, J1
Cui, Q1
Pu, C1
Liang, B1
Luo, Y1
Shi, J1
Jin, A1
Xiao, L1
Huang, H1
Walid, MS1
Ajjan, M1
Grigorian, AA1
Bernstein, RA1
Gibbs, M1
Hunt Batjer, H1
Cohen, JE1
Itshayek, E1
Attia, M1
Moscovici, S1
Rigual, D1
Qiu, J1
Fenstermaker, RA1
Fabiano, AJ1
Pettersen, JA1
Zochodne, DW1
Bell, RB1
Martin, L1
Hill, MD1
van der Flier, M1
Hoppenreijs, S1
van Rensburg, AJ1
Ruyken, M1
Kolk, AH1
Springer, P1
Hoepelman, AI1
Geelen, SP1
Kimpen, JL1
Schoeman, JF1
Kincaid, O1
Rowin, J1
Epelboin, L1
Klement, E1
Chemali, N1
Danis, M1
Bricaire, E1
Caumes, E1
Smith, RA1
Smith, WA1
Madsen, M1
Kissmeyer-Nielsen, F1
Rasmussen, P1
Andersen, P1
Gutin, PH1
Pfeiffer, M1
Griss, P1
Hess, J1
Bogousslavsky, J1
Regli, F1
Kalina, P1
Orolin, D1
Neville, BG1
Wilson, J1
Brennan, MJ1
Klastersky, J1
Chretien, JH1
Garagusi, VF1
Vích, V1
Luyendijk, W1
Verhoog, BD1
Gläsel, E1
Maxwell, RE1
Long, DM1
French, LA1
Christensen, BE1

Reviews

3 reviews available for prednisone and Brain Edema

ArticleYear
Corticosteroid therapy in patients with cerebral tumors: benefits, mechanisms, problems, practicalities.
    Seminars in oncology, 1975, Volume: 2, Issue:1

    Topics: Adrenal Cortex Hormones; Animals; Blood-Brain Barrier; Brain Edema; Brain Neoplasms; Cell Division;

1975
Corticosteroids in the treatment of solid tumors.
    The Medical clinics of North America, 1973, Volume: 57, Issue:5

    Topics: Adrenal Cortex Hormones; Antineoplastic Agents; Brain Edema; Brain Neoplasms; Breast Neoplasms; Chil

1973
Effectiveness of adrenal corticosteroids in the management of severe bacterial infections.
    Revue europeenne d'etudes cliniques et biologiques. European journal of clinical and biological research, 1971, Volume: 16, Issue:5

    Topics: Adrenal Glands; Animals; Anti-Bacterial Agents; Bacterial Infections; Betamethasone; Brain Edema; Ce

1971

Trials

1 trial available for prednisone and Brain Edema

ArticleYear
Predominant cerebral cytokine release syndrome in CD19-directed chimeric antigen receptor-modified T cell therapy.
    Journal of hematology & oncology, 2016, 08-15, Volume: 9, Issue:1

    Topics: Adult; Antigens, CD19; Blood-Brain Barrier; Brain Edema; Cytokines; Female; Humans; Immunotherapy, A

2016

Other Studies

23 other studies available for prednisone and Brain Edema

ArticleYear
Case Report: A Case of Severe Cryptococcal Immune Reconstitution Inflammatory Syndrome Presenting with Brain and Intradural Abscesses in an HIV Patient.
    The American journal of tropical medicine and hygiene, 2020, Volume: 103, Issue:2

    Topics: Acquired Immunodeficiency Syndrome; Amphotericin B; Anti-Inflammatory Agents; Anti-Retroviral Agents

2020
A case of COVID-19 infection presenting with a seizure following severe brain edema.
    Seizure, 2020, Volume: 80

    Topics: Adult; Anti-Bacterial Agents; Anticoagulants; Anticonvulsants; Azithromycin; Betacoronavirus; Brain

2020
Polyarteritis nodosa complicated by posterior reversible encephalopathy syndrome: a case report.
    Nefrologia : publicacion oficial de la Sociedad Espanola Nefrologia, 2014, Nov-17, Volume: 34, Issue:6

    Topics: Adult; Amaurosis Fugax; Aneurysm; Brain Edema; Celiac Artery; Combined Modality Therapy; Humans; Hyp

2014
Neurosarcoidosis--the great mimicker.
    Journal of the National Medical Association, 2008, Volume: 100, Issue:7

    Topics: Adult; Anti-Inflammatory Agents; Brain Edema; Craniotomy; Diagnosis, Differential; Facial Paralysis;

2008
Clinical diagnosis and successful treatment of inflammatory cerebral amyloid angiopathy.
    Neurocritical care, 2011, Volume: 14, Issue:3

    Topics: Aged; Anticonvulsants; Apolipoprotein E4; Brain Edema; Cerebral Amyloid Angiopathy, Familial; Diffus

2011
Postembolization perianeurysmal edema as a cause of uncinate seizures.
    Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, 2012, Volume: 19, Issue:3

    Topics: Anti-Inflammatory Agents; Brain Edema; Cerebral Angiography; Electroencephalography; Embolization, T

2012
Tumoral Bing-Neel Syndrome presenting as a cerebellar mass.
    Clinical neurology and neurosurgery, 2013, Volume: 115, Issue:6

    Topics: Anti-Inflammatory Agents; Antibodies, Monoclonal, Murine-Derived; Antineoplastic Agents; Antineoplas

2013
Refractory neurosarcoidosis responding to infliximab.
    Neurology, 2002, Nov-26, Volume: 59, Issue:10

    Topics: Anti-Inflammatory Agents; Antibodies, Monoclonal; Brain; Brain Diseases; Brain Edema; Drug Resistanc

2002
Vascular endothelial growth factor and blood-brain barrier disruption in tuberculous meningitis.
    The Pediatric infectious disease journal, 2004, Volume: 23, Issue:7

    Topics: Albumins; Antitubercular Agents; Blood-Brain Barrier; Brain Edema; Child; Child, Preschool; Drug The

2004
Intracranial hypertension causing polyradiculopathy and late or absent F-waves.
    Journal of neurology, neurosurgery, and psychiatry, 2006, Volume: 77, Issue:12

    Topics: Adult; Anti-Inflammatory Agents; Brain Edema; Diuretics; Electroencephalography; Humans; Intracrania

2006
[Neurocysticercosis complicating the treatment of cutaneous cysticercosis in a traveller].
    Bulletin de la Societe de pathologie exotique (1990), 2004, Volume: 97, Issue:4

    Topics: Adult; Albendazole; Anthelmintics; Brain Edema; Combined Modality Therapy; Confusion; Cysticercosis;

2004
Steroid therapy of cerebral edema.
    Journal of the Medical Association of Georgia, 1967, Volume: 56, Issue:8

    Topics: Adult; Aged; Brain Edema; Brain Neoplasms; Dexamethasone; Female; Glucocorticoids; Humans; Male; Met

1967
Decreased expression of HLA-DR antigens on peripheral blood B lymphocytes during glucocorticoid treatment.
    Tissue antigens, 1981, Volume: 17, Issue:2

    Topics: Antigen-Antibody Reactions; B-Lymphocytes; Brain Edema; Cytotoxicity Tests, Immunologic; Dexamethaso

1981
[Craniocerebral trauma and aseptic osteonecrosis. Steroid-induced sequelae after therapy of brain edema].
    Der Unfallchirurg, 1992, Volume: 95, Issue:6

    Topics: Adolescent; Adult; Brain Edema; Brain Injuries; Cortisone; Female; Femur Head Necrosis; Humans; Male

1992
[Involvement of the central nervous system in a case of Behçet's disease].
    Revue medicale de la Suisse romande, 1991, Volume: 111, Issue:5

    Topics: Adult; Azathioprine; Behcet Syndrome; Brain Edema; Drug Therapy, Combination; Female; Humans; Magnet

1991
[Treatment of brain edema in intracranial tumors using corticoids].
    Ceskoslovenska neurologie a neurochirurgie, 1985, Volume: 48, Issue:6

    Topics: Brain Edema; Brain Neoplasms; Dexamethasone; Female; Humans; Male; Middle Aged; Prednisone; Retrospe

1985
Benign intracranial hypertension following corticosteroid withdrawal in childhood.
    British medical journal, 1970, Sep-05, Volume: 3, Issue:5722

    Topics: Adolescent; Adrenocorticotropic Hormone; Brain Diseases; Brain Edema; Calcium; Cerebral Ventriculogr

1970
Corticosteroid effect on phagocytosis and NBT reduction by human polymorphonuclear neutrophils.
    Journal of the Reticuloendothelial Society, 1972, Volume: 11, Issue:4

    Topics: Adult; Aged; Brain Edema; Cardiomyopathies; Depression, Chemical; Dexamethasone; Female; Humans; Hyd

1972
[Significance of brain edema for the pediatric cardiorheumatologist].
    Ceskoslovenska pediatrie, 1969, Volume: 24, Issue:4

    Topics: Brain Edema; Child; Female; Heart Diseases; Humans; Hypersensitivity; Infant; Male; Prednisone; Rheu

1969
[Benign intracranial hypertension; a possible result of St. Louis encephalitis].
    Nederlands tijdschrift voor geneeskunde, 1970, Jul-11, Volume: 114, Issue:28

    Topics: Adult; Brain Edema; Encephalitis, St. Louis; Female; Glycerol; Humans; Hypertension; Intracranial Pr

1970
[Clinical aspect and therapy of a severe acute dinitroorthocresol poisoning].
    Zeitschrift fur die gesamte innere Medizin und ihre Grenzgebiete, 1970, Apr-15, Volume: 25, Issue:8

    Topics: Acidosis; Adenosine Triphosphate; Adult; Bicarbonates; Bloodletting; Brain Edema; Carbohydrates; Cre

1970
The effects of glucosteroids on experimental cold-induced brain edema. Gross morphological alterations and vascular permeability changes.
    Journal of neurosurgery, 1971, Volume: 34, Issue:4

    Topics: Animals; Brain; Brain Edema; Capillary Permeability; Cats; Cerebral Cortex; Cerebrovascular Disorder

1971
[Metyrapone incombination with spironolactone and prednisone in the therapy of severe edema].
    Nordisk medicin, 1968, Aug-15, Volume: 80, Issue:33

    Topics: Aged; Brain Edema; Drug Synergism; Edema; Female; Humans; Hyperkalemia; Hyponatremia; Metyrapone; Mi

1968