prednisone has been researched along with Blast Phase in 21 studies
Prednisone: A synthetic anti-inflammatory glucocorticoid derived from CORTISONE. It is biologically inert and converted to PREDNISOLONE in the liver.
prednisone : A synthetic glucocorticoid drug that is particularly effective as an immunosuppressant, and affects virtually all of the immune system. Prednisone is a prodrug that is converted by the liver into prednisolone (a beta-hydroxy group instead of the oxo group at position 11), which is the active drug and also a steroid.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A patient with a lymphoid blast crisis of a chronic myelogenous leukemia (CML) was treated with vindesine, vincristine and prednisone." | 7.69 | Possible effect of medroxyprogesterone acetate (MPA) in lymphoid blast crisis of chronic myelogenous leukemia. ( Fink, M, 1994) |
| " Of eight CML patients in blast crisis (BC) with normal P-gp expression, partial remission was achieved in three and minor response in five after prednisone/vindesine therapy." | 3.69 | Clinical importance of P-glycoprotein-related resistance in leukemia and myelodysplastic syndromes--first experience with their reversal. ( Bartl, R; Beckert, B; Bock, S; Gieseler, F; Gullis, E; Nerl, C; Nüssler, V; Pelka-Fleischer, R; Petrides, PE; Zwierzina, H, 1994) |
| "A patient with a lymphoid blast crisis of a chronic myelogenous leukemia (CML) was treated with vindesine, vincristine and prednisone." | 3.69 | Possible effect of medroxyprogesterone acetate (MPA) in lymphoid blast crisis of chronic myelogenous leukemia. ( Fink, M, 1994) |
| "The regimen for acute lymphocytic leukemia was idarubicin 8 mg/m2, dl - 3; vincristine 2 mg/mr, dl; cyclophosphamide 750 mg/m2, dl ; plus prednisone 60 mg/m(2),dl - 14 for 1-2 cycles." | 2.72 | [Multicenter randomized control trial on safety of domestic idarubicin for acute leukemia]. ( Du, X; Ke, XY; Liu, Y; Lu, ZS; Lv, JQ; Ma, J; Shen, ZX; Xu, XH; Zeng, XY; Zhan, ZM; Zhang, XH; Zhao, YM, 2006) |
| "Acute myelofibrosis (AMF), as defined by an acute panmyelopathy associated with marked megakaryocytic hyperplasia and marrow fibrosis, appears to be a stem cell disorder." | 2.39 | Acute myelofibrosis terminating in acute lymphoblastic leukemia: case report and review of the literature. ( Dunphy, CH; Kitchen, S; Saravia, O; Velasquez, WS, 1996) |
| "In childhood acute lymphoblastic leukemia (ALL), persistence of leukemic blasts during therapy is of crucial prognostic significance." | 1.34 | Gene expression shift towards normal B cells, decreased proliferative capacity and distinct surface receptors characterize leukemic blasts persisting during induction therapy in childhood acute lymphoblastic leukemia. ( Hagemeier, C; Karawajew, L; Kirschner-Schwabe, R; Ludwig, WD; Moericke, A; Ratei, R; Rhein, P; Scheid, S; Schrappe, M; Seeger, K; Spang, R, 2007) |
| "Childhood Acute Lymphoblastic Leukemia (ALL) represents approximately 40% of pediatric cancers, but molecular mechanisms involved in the therapeutic resistance of ALL are still unclear." | 1.32 | Glucocorticoids induce G1 arrest of lymphoblastic cells through retinoblastoma protein Rb1 dephosphorylation in childhood acute lymphoblastic leukemia in vivo. ( Abbruzzese, A; Addeo, R; Caraglia, M; Casale, F; Crisci, S; D'Angelo, V; Di Tullio, MT; Indolfi, P, 2004) |
| "Prednisone good response was defined as a blast count of less than 1,000/microL and a prednisone poor response (PPR) as a blast count of at least 1,000/microL, both in peripheral smears, after 7 days of oral prednisone (60 mg/m2 per day) and one intrathecal dose of methotrexate." | 1.31 | Childhood acute lymphoblastic leukemia: prognostic value of initial peripheral blast count in good responders to prednisone. ( Alfaro, EM; Felice, MS; Sackmann-Muriel, F; Zubizarreta, PA, 2001) |
| "In 74% of the acute myeloid leukemia patients, the truncated inhibitor was detected." | 1.29 | Urinary excretion of proteolyzed alpha1-antitrypsin: specificity, quantitation, and relation to therapy response in patients with acute myeloid leukemia. ( Busch, R; Dengler, R; Eger, G; Emmerich, B; Münstermann, U; Plewan, A, 1995) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (9.52) | 18.7374 |
| 1990's | 10 (47.62) | 18.2507 |
| 2000's | 8 (38.10) | 29.6817 |
| 2010's | 1 (4.76) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Cario, G | 1 |
| Fetz, A | 1 |
| Bretscher, C | 1 |
| Möricke, A | 1 |
| Schrauder, A | 1 |
| Stanulla, M | 1 |
| Schrappe, M | 2 |
| Tucci, F | 1 |
| Aricò, M | 1 |
| Santos, FP | 1 |
| Rodrigues, M | 1 |
| Mac-Donald Bley do Nascimento, C | 1 |
| Kerbauy, FR | 1 |
| Ribeiro, AA | 1 |
| Mauro Kutner, J | 1 |
| Hamerschlak, N | 1 |
| Fain, O | 1 |
| Gérin, M | 1 |
| Bibi-Triki, T | 1 |
| Braun, T | 1 |
| Fenaux, P | 1 |
| Addeo, R | 1 |
| Casale, F | 1 |
| Caraglia, M | 1 |
| D'Angelo, V | 1 |
| Crisci, S | 1 |
| Abbruzzese, A | 1 |
| Di Tullio, MT | 1 |
| Indolfi, P | 1 |
| Liu, Y | 1 |
| Ke, XY | 1 |
| Ma, J | 1 |
| Shen, ZX | 1 |
| Zhang, XH | 1 |
| Du, X | 1 |
| Zhao, YM | 1 |
| Lv, JQ | 1 |
| Zhan, ZM | 1 |
| Zeng, XY | 1 |
| Xu, XH | 1 |
| Lu, ZS | 1 |
| Rhein, P | 1 |
| Scheid, S | 1 |
| Ratei, R | 1 |
| Hagemeier, C | 1 |
| Seeger, K | 1 |
| Kirschner-Schwabe, R | 1 |
| Moericke, A | 1 |
| Spang, R | 1 |
| Ludwig, WD | 1 |
| Karawajew, L | 1 |
| Nüssler, V | 1 |
| Pelka-Fleischer, R | 1 |
| Zwierzina, H | 1 |
| Nerl, C | 1 |
| Beckert, B | 1 |
| Gullis, E | 1 |
| Gieseler, F | 1 |
| Bock, S | 1 |
| Bartl, R | 1 |
| Petrides, PE | 1 |
| Fink, M | 1 |
| Ambrosetti, A | 1 |
| Krampera, M | 1 |
| Veneri, D | 1 |
| Meneghini, V | 1 |
| Aprili, F | 1 |
| Martinelli, G | 1 |
| Pizzolo, G | 1 |
| Perona, G | 1 |
| Dunphy, CH | 1 |
| Kitchen, S | 1 |
| Saravia, O | 1 |
| Velasquez, WS | 1 |
| Meloni, G | 1 |
| Capria, S | 1 |
| Vignetti, M | 1 |
| Mandelli, F | 1 |
| Modena, V | 1 |
| Dengler, R | 1 |
| Plewan, A | 1 |
| Münstermann, U | 1 |
| Busch, R | 1 |
| Eger, G | 1 |
| Emmerich, B | 1 |
| Kaplan, SS | 1 |
| Rybka, WB | 1 |
| Blom, J | 1 |
| Shekhter-Levin, S | 1 |
| Griffin, TC | 1 |
| Shuster, JJ | 1 |
| Buchanan, GR | 1 |
| Murphy, SB | 1 |
| Camitta, BM | 1 |
| Amylon, MD | 1 |
| Felice, MS | 1 |
| Zubizarreta, PA | 1 |
| Alfaro, EM | 1 |
| Sackmann-Muriel, F | 1 |
| Cervantes, F | 1 |
| Urbano-Ispizua, A | 1 |
| Escoda, L | 1 |
| Ordi, J | 1 |
| Montserrat, E | 1 |
| Rozman, C | 1 |
| Kantarjian, HM | 1 |
| Talpaz, M | 1 |
| Keating, MJ | 1 |
| Estey, EH | 1 |
| O'Brien, S | 1 |
| Beran, M | 1 |
| McCredie, KB | 1 |
| Gutterman, J | 1 |
| Freireich, EJ | 1 |
| Heyll, A | 1 |
| Derigs, G | 1 |
| Zhang, ZY | 1 |
| Hou, CH | 1 |
| Zhu, YF | 1 |
| You, XY | 1 |
| Li, JL | 1 |
| Fu, Z | 1 |
| Paciucci, PA | 1 |
| Keaveney, C | 1 |
| Cuttner, J | 1 |
| Holland, JF | 1 |
1 review available for prednisone and Blast Phase
| Article | Year |
|---|---|
Acute myelofibrosis terminating in acute lymphoblastic leukemia: case report and review of the literature.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Blast Crisis; Bone Marrow; Chro | 1996 |
2 trials available for prednisone and Blast Phase
| Article | Year |
|---|---|
[Multicenter randomized control trial on safety of domestic idarubicin for acute leukemia].
Topics: Adolescent; Adult; Aged; Agranulocytosis; Antibiotics, Antineoplastic; Antineoplastic Combined Chemo | 2006 |
Slow disappearance of peripheral blood blasts is an adverse prognostic factor in childhood T cell acute lymphoblastic leukemia: a Pediatric Oncology Group study.
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Blast Crisis; Child; Confi | 2000 |
18 other studies available for prednisone and Blast Phase
| Article | Year |
|---|---|
Initial leukemic gene expression profiles of patients with poor in vivo prednisone response are similar to those of blasts persisting under prednisone treatment in childhood acute lymphoblastic leukemia.
Topics: Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Blast Crisis; Child; Daunorubicin; Gen | 2008 |
Treatment of pediatric acute lymphoblastic leukemia.
Topics: Antineoplastic Agents; Blast Crisis; Child; Child, Preschool; Humans; Injections, Spinal; Meningeal | 2008 |
Philadelphia-negative acute lymphoblastic leukemia in a chronic myeloid leukemia patient receiving dasatinib.
Topics: Aged; Antineoplastic Agents; Benzamides; Blast Crisis; Dasatinib; Hematopoietic Stem Cell Transplant | 2010 |
[Relapsing polychondritis and chronic myelomonocytic leukemia].
Topics: Blast Crisis; Glucocorticoids; Humans; Leukemia, Myelomonocytic, Chronic; Male; Middle Aged; Polycho | 2009 |
Glucocorticoids induce G1 arrest of lymphoblastic cells through retinoblastoma protein Rb1 dephosphorylation in childhood acute lymphoblastic leukemia in vivo.
Topics: Blast Crisis; Cell Cycle Proteins; Child; Cyclins; Female; G1 Phase; Glucocorticoids; Humans; Male; | 2004 |
Gene expression shift towards normal B cells, decreased proliferative capacity and distinct surface receptors characterize leukemic blasts persisting during induction therapy in childhood acute lymphoblastic leukemia.
Topics: Adolescent; B-Lymphocytes; Blast Crisis; CD11b Antigen; Cell Cycle; Cell Proliferation; Child; Child | 2007 |
Clinical importance of P-glycoprotein-related resistance in leukemia and myelodysplastic syndromes--first experience with their reversal.
Topics: Adult; Antibodies, Monoclonal; ATP Binding Cassette Transporter, Subfamily B, Member 1; Base Sequenc | 1994 |
Possible effect of medroxyprogesterone acetate (MPA) in lymphoid blast crisis of chronic myelogenous leukemia.
Topics: Blast Crisis; Blood Cells; Bone Marrow; Drug Therapy, Combination; Female; Humans; Leukemia, Myeloge | 1994 |
Early lymphoid blastic crisis following major karyotypic conversion in a chronic myeloid leukemia patient treated with interferon-alpha.
Topics: Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Blast Crisis; Child; Cytarabine; Dauno | 1994 |
Blast crisis of chronic myelogenous leukemia in long-lasting systemic lupus erythematosus: regression of both diseases after autologous bone marrow transplantation.
Topics: Adult; Amsacrine; Antineoplastic Combined Chemotherapy Protocols; Autoimmune Diseases; Blast Crisis; | 1997 |
Urinary excretion of proteolyzed alpha1-antitrypsin: specificity, quantitation, and relation to therapy response in patients with acute myeloid leukemia.
Topics: Adult; Aged; alpha 1-Antitrypsin; Aminoglutethimide; Antineoplastic Combined Chemotherapy Protocols; | 1995 |
Tetraploidy in acute myeloid leukemia secondary to large cell lymphoma.
Topics: Acute Disease; Aged; Antineoplastic Combined Chemotherapy Protocols; Blast Crisis; Chromosome Aberra | 1998 |
Childhood acute lymphoblastic leukemia: prognostic value of initial peripheral blast count in good responders to prednisone.
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Blast Crisis; Child; Child, Preschool; D | 2001 |
[T lymphoid blast crisis of Philadelphia chromosome-positive chronic myeloid leukemia: analysis of 3 cases].
Topics: Adult; Blast Crisis; Humans; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Male; Middle Aged; Ph | 1991 |
Intensive chemotherapy induction followed by interferon-alpha maintenance in patients with Philadelphia chromosome-positive chronic myelogenous leukemia.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Blast Crisis; Bone Marrow Transpl | 1991 |
Chronic myelomonocytic leukemia: clinical data, morphological features, and outcome in 56 patients.
Topics: Biomarkers, Tumor; Blast Crisis; Bone Marrow; Cytarabine; Germany, West; Hemorrhage; Humans; Leukemi | 1990 |
Curative effect of harringtonine semisynthetic harringtonine and HOAP on nonlymphocytic leukemias. Analysis of 304 cases.
Topics: Adult; Alkaloids; Antineoplastic Combined Chemotherapy Protocols; Blast Crisis; Cytarabine; Female; | 1987 |
Mitoxantrone, vincristine, and prednisone in adults with relapsed or primarily refractory acute lymphocytic leukemia and terminal deoxynucleotidyl transferase positive blastic phase chronic myelocytic leukemia.
Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Blast Crisis; Bone Marrow; | 1987 |