Page last updated: 2024-11-07

prednisone and Birth Weight

prednisone has been researched along with Birth Weight in 38 studies

Prednisone: A synthetic anti-inflammatory glucocorticoid derived from CORTISONE. It is biologically inert and converted to PREDNISOLONE in the liver.
prednisone : A synthetic glucocorticoid drug that is particularly effective as an immunosuppressant, and affects virtually all of the immune system. Prednisone is a prodrug that is converted by the liver into prednisolone (a beta-hydroxy group instead of the oxo group at position 11), which is the active drug and also a steroid.

Birth Weight: The mass or quantity of heaviness of an individual at BIRTH. It is expressed by units of pounds or kilograms.

Research Excerpts

ExcerptRelevanceReference
"Children who are prednisone-exposed in utero (low dose) have no increased risk for insulin resistance at the age of approximately 7 years."8.31Does prednisone use in pregnant women with rheumatoid arthritis induce insulin resistance in the offspring? ( de Steenwinkel, FDO; Dolhain, RJEM; Hazes, JMW; Hokken-Koelega, ACS, 2023)
"The present report reconfirms the safety of tacrolimus during pregnancy after LTx."7.72Pregnancy after liver transplantation with tacrolimus immunosuppression: a single center's experience update at 13 years. ( Cacciarelli, TV; de Vera, ME; Eghtesad, B; Fontes, PA; Fung, JJ; Jain, AB; Marcos, A; Marsh, JW; Mazariegos, G; Rafail, A; Reyes, J; Starzl, TE, 2003)
"Children who are prednisone-exposed in utero (low dose) have no increased risk for insulin resistance at the age of approximately 7 years."4.31Does prednisone use in pregnant women with rheumatoid arthritis induce insulin resistance in the offspring? ( de Steenwinkel, FDO; Dolhain, RJEM; Hazes, JMW; Hokken-Koelega, ACS, 2023)
" To examine the independent influence of prednisone use and disease activity on birth weight, regression analyses were performed, with adjustments for gestational age of the child at delivery, the sex of the newborn, and the mother's smoking status, education level, parity, and use of an assisted reproduction technique."3.75Association of higher rheumatoid arthritis disease activity during pregnancy with lower birth weight: results of a national prospective study. ( de Groot, CJ; de Man, YA; Dolhain, RJ; Hazes, JM; Steegers, EA; van der Heide, H; Willemsen, SP, 2009)
"The present report reconfirms the safety of tacrolimus during pregnancy after LTx."3.72Pregnancy after liver transplantation with tacrolimus immunosuppression: a single center's experience update at 13 years. ( Cacciarelli, TV; de Vera, ME; Eghtesad, B; Fontes, PA; Fung, JJ; Jain, AB; Marcos, A; Marsh, JW; Mazariegos, G; Rafail, A; Reyes, J; Starzl, TE, 2003)
"We report on the outcome of 56 pregnancies in 51 women with severe asthma requiring prednisone and/or beclomethasone dipropionate."3.67Outcome of pregnancy in women requiring corticosteroids for severe asthma. ( Fitzsimons, R; Greenberger, PA; Patterson, R, 1986)
"Prednisone treatment for infertility and subsequent pregnancy maintenance in humans resulted in a significant decrease in the birth weight of full-term infants and a marked increase in the percentage of newborn infants weighing 2500 grams or less, that is, "light for dates" in comparison to control offspring."3.66Prenatal exposure to prednisone in humans and animals retards intrauterine growth. ( Gandelman, R; Karow, WG; Reinisch, JM; Simon, NG, 1978)
"Aggressive treatment with cytarabine, vincristine sulfate, and prednisone for acute myelogenous leukemia, administered from the 31 st week of pregnancy, resulted in both sustained complete remission of the leukemia and delivery of a normal infant with a normal birthweight and a normal male karyotype."3.65Successful treatment of acute leukemia during pregnancy. Combination therapy in the third trimester. ( Durie, BG; Giles, HR, 1977)
"Transitory neonatal myasthenia gravis (TNMG) was diagnosed in 30% infants."2.41Myasthenia gravis in pregnancy: report on 69 cases. ( Djelmis, J; Ivanisevic, M; Mayer, D; Sostarko, M, 2002)
" Thereafter, this therapy may need to be continued, often at an extremely low dosage level, sometimes intermittently, for many years before the hemoglobin value maintains itself without medication."2.35Congenital hypoplastic anemia. ( Alter, BP; Diamond, LK; Wang, WC, 1976)
"Active lupus nephritis is a predictor for poor outcomes of pregnancies in SLE patients."1.43[Analysis of pregnancy outcomes in 66 patients with systemic lupus erythematosus]. ( Chen, JM; Song, XZ; Zhou, QG, 2016)
"Thrombocytopenia was in 13 cases due to immunization to HPA-1a, in one case to HPA-5b, and in one case to HPA-6b."1.30Prenatal treatment of severe fetomaternal alloimmune thrombocytopenia. ( Kekomäki, R; Sainio, S; Teramo, K, 1999)
"Mean birth weight was 2."1.28[Pregnancy after renal transplantation. 27 patients and review of the literature]. ( Edouard, D; Fernandez, H; Frydman, R; Ville, Y, 1992)
"The peak incidence of Hodgkin's disease occurs during the reproductive age, and its association with pregnancy is at a rate of between 1:1,000-1:6,000."1.28Maternal and foetal outcome following Hodgkin's disease in pregnancy. ( Degendorfer, P; Koren, G; Lishner, M; Panzarella, T; Sutcliffe, SB; Zemlickis, D, 1992)

Research

Studies (38)

TimeframeStudies, this research(%)All Research%
pre-199026 (68.42)18.7374
1990's4 (10.53)18.2507
2000's3 (7.89)29.6817
2010's4 (10.53)24.3611
2020's1 (2.63)2.80

Authors

AuthorsStudies
de Steenwinkel, FDO1
Dolhain, RJEM1
Hazes, JMW1
Hokken-Koelega, ACS1
Ye, SL1
Gu, XK1
Tao, LY1
Cong, JM1
Wang, YQ1
de Steenwinkel, FD1
Hokken-Koelega, AC1
de Ridder, MA1
Hazes, JM2
Dolhain, RJ2
Song, XZ1
Chen, JM1
Zhou, QG1
de Man, YA1
van der Heide, H1
Willemsen, SP1
de Groot, CJ1
Steegers, EA1
Lorente, B1
Sabadell, J1
Serrano, A1
Alvarez, M1
Sánchez Iglesias, JL1
Suy, A1
Cabero, L1
Djelmis, J1
Sostarko, M1
Mayer, D1
Ivanisevic, M1
DAVEY, DA1
JOPLIN, GF1
SANTANDER, R1
HERRE, HD1
RAZON, S1
MAZZOLA, G1
KAEDING, A1
HENNING, L1
Jain, AB1
Reyes, J1
Marcos, A1
Mazariegos, G1
Eghtesad, B1
Fontes, PA1
Cacciarelli, TV1
Marsh, JW1
de Vera, ME1
Rafail, A1
Starzl, TE1
Fung, JJ1
Berardinelli, L1
Dallatana, R1
Beretta, C1
Raiteri, M1
Tonello, G1
Quaglia, F1
Vegeto, A1
Billis, A1
Rastogi, GK1
Yackel, DB1
Kempers, RD1
McConahey, WM1
Logaridis, TE1
Doran, TA1
Scott, JG1
Gare, DG1
Comtesse, C1
Barden, TP1
Knowles, HC1
Lee, F1
Nelson, N1
Faiman, C1
Choi, NW1
Reyes, FI1
Sainio, S1
Teramo, K1
Kekomäki, R1
Koppe, JG1
Smolders-de Haas, H1
Kloosterman, GJ1
Durie, BG1
Giles, HR1
Jefferies, WM1
Smith, KD1
Steinberger, E1
Rodriguez-Rigau, LJ1
Reinisch, JM1
Simon, NG1
Karow, WG1
Gandelman, R1
Diamond, LK1
Wang, WC1
Alter, BP1
Ville, Y1
Fernandez, H1
Edouard, D1
Frydman, R1
Lishner, M1
Zemlickis, D1
Degendorfer, P1
Panzarella, T1
Sutcliffe, SB1
Koren, G1
Fitzsimons, R1
Greenberger, PA1
Patterson, R1
Bobrow, M1
Emerson, PM1
Spriggs, AI1
Ellis, HL1
Mussa, GC1
Bacolla, D1
Martini Mauri, M1
Favetta, S1
Bona, G1
Merrill, LK1
Board, JA1
Lee, HM1
Nolan, GH1
Sweet, RL1
Laros, RK1
Roure, CA1
Sharon, E1
Jones, J1
Diamond, H1
Kaplan, D1
Wieczorkiewicz, T1
Dawidowicz, A1
Charzewski, J1
Symonowicz, N1
Holtorff, J2
Haller, H2
Strauzenberg, E1
Dommergues, JP1
Vassoyan, J1
Alagille, D1
Strauzenberg, SE1
Löffler, F1
Beissert, M1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
PreConceptional Counselling in Active Rheumatoid Arthritis[NCT01345071]150 participants (Anticipated)Observational2011-09-30Recruiting
Phase I/II, Open-Label Study to Determine Safety and Efficacy of Sotatercept (ACE-011) in Adults With Red Blood Cell Transfusion- Dependent Diamond Blackfan Anemia[NCT01464164]Phase 1/Phase 219 participants (Actual)Interventional2012-01-31Terminated (stopped due to Supporter terminated the study due to no active patients (secondary to travel restrictions due to COVID).)
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Number of Participants With Complete Response and Partial Response

Complete response is transfusion independence with hemoglobin >9 gm/dl; partial response is transfusion dependence with hemoglobin < 9gm/dl with an increase in reticulocyte count over baseline (NCT01464164)
Timeframe: 9 months

InterventionParticipants (Count of Participants)
Sotatercept Cohort 10
Sotatercept Cohort 20
Sotatercept Cohort 30
Sotatercept With Prednisone Boost Cohort 4a0
Sotatercept Cohort 4b0
Sotatercept With Prednisone Boost Cohort 5a0
Sotatercept Cohort 5b0

Severe Adverse Events Attributable to Study Drug

Assess severity of adverse events and relationship to sotatercept according to the currently active minor version of the NCI Common Terminology for Adverse Events version 4.0 (NCT01464164)
Timeframe: 9 months

InterventionParticipants (Count of Participants)
Sotatercept Cohort 10
Sotatercept Cohort 20
Sotatercept Cohort 30
Sotatercept With Prednisone Boost Cohort 4a0
Sotatercept Cohort 4b0
Sotatercept With Prednisone Boost Cohort 5a0
Sotatercept Cohort 5b0

Reviews

4 reviews available for prednisone and Birth Weight

ArticleYear
Myasthenia gravis in pregnancy: report on 69 cases.
    European journal of obstetrics, gynecology, and reproductive biology, 2002, Aug-05, Volume: 104, Issue:1

    Topics: Adult; Birth Weight; Breast Feeding; Cesarean Section; Comorbidity; Female; Humans; Hyperbilirubinem

2002
The effect of maternal steroid administration on fetal platelet count in immunologic thrombocytopenic purpura. Management of pregnancy and mode of delivery.
    American journal of obstetrics and gynecology, 1983, Jan-15, Volume: 145, Issue:2

    Topics: Adrenal Cortex Hormones; Adult; Autoantibodies; Birth Weight; Blood Platelets; Cesarean Section; Del

1983
Diagnosis of diabetes in pregnancy.
    Clinical obstetrics and gynecology, 1981, Volume: 24, Issue:1

    Topics: Adult; Birth Weight; Blood Glucose; Cortisone; Female; Glucose Tolerance Test; Glycosuria; Humans; I

1981
Congenital hypoplastic anemia.
    Advances in pediatrics, 1976, Volume: 22

    Topics: Adolescent; Anemia, Aplastic; Birth Weight; Blood Transfusion; Child; Child, Preschool; Diagnosis, D

1976

Other Studies

34 other studies available for prednisone and Birth Weight

ArticleYear
Does prednisone use in pregnant women with rheumatoid arthritis induce insulin resistance in the offspring?
    Clinical rheumatology, 2023, Volume: 42, Issue:1

    Topics: Adiponectin; Arthritis, Rheumatoid; Birth Weight; Child; Female; Glucocorticoids; Humans; Insulin; I

2023
Efficacy of Different Treatment Regimens for Antiphospholipid Syndrome-related Recurrent Spontaneous Abortion.
    Chinese medical journal, 2017, Jun-20, Volume: 130, Issue:12

    Topics: Abortion, Habitual; Adult; Anti-Inflammatory Agents; Anticoagulants; Antiphospholipid Syndrome; Birt

2017
Rheumatoid arthritis during pregnancy and postnatal catch-up growth in the offspring.
    Arthritis & rheumatology (Hoboken, N.J.), 2014, Volume: 66, Issue:7

    Topics: Adult; Antirheumatic Agents; Arthritis, Rheumatoid; Birth Weight; Child Development; Child, Preschoo

2014
[Analysis of pregnancy outcomes in 66 patients with systemic lupus erythematosus].
    Nan fang yi ke da xue xue bao = Journal of Southern Medical University, 2016, Dec-20, Volume: 36, Issue:12

    Topics: Birth Weight; Female; Humans; Infant, Newborn; Lupus Erythematosus, Systemic; Lupus Nephritis; Predn

2016
Association of higher rheumatoid arthritis disease activity during pregnancy with lower birth weight: results of a national prospective study.
    Arthritis and rheumatism, 2009, Volume: 60, Issue:11

    Topics: Adult; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Birth Weight; Female; Gestational Age; Human

2009
Mediastinal tumor during pregnancy: a multidisciplinary approach.
    Journal of perinatal medicine, 2010, Volume: 38, Issue:6

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Birth Weight; Cesarean Section; Cyclophospham

2010
Prediabetes in mothers of large infants.
    Lancet (London, England), 1961, Jul-08, Volume: 2, Issue:7193

    Topics: Birth Weight; Diabetes Mellitus; Female; Glycosuria; Humans; Infant; Mothers; Prediabetic State; Pre

1961
[THE USE OF THE PREDNISONE-GLYCOSURIA TEST IN OBSTETRICS FOR THE DIAGNOSIS OF PREDIABETES].
    Zentralblatt fur Gynakologie, 1963, Sep-14, Volume: 85

    Topics: Birth Weight; Diabetes Mellitus; Diagnosis; Female; Glycosuria; Humans; Infant; Infant Mortality; Ob

1963
[IMMEDIATE EFFECTS OF CORTICOSTEROID THERAPY IN GRAVE JAUNDICE OF THE NEWBORN].
    La Pediatria, 1964, Aug-31, Volume: 72

    Topics: ABO Blood-Group System; Adrenal Cortex Hormones; Betamethasone; Birth Weight; Dyspepsia; Erythroblas

1964
[ON THE PREDNISONE-GLUCOSE TOLERANCE TEST. II].
    Zeitschrift fur die gesamte innere Medizin und ihre Grenzgebiete, 1964, May-15, Volume: 19

    Topics: Adolescent; Birth Weight; Child; Diabetes Mellitus; Diagnosis; Genetics, Medical; Geriatrics; Glucos

1964
Pregnancy after liver transplantation with tacrolimus immunosuppression: a single center's experience update at 13 years.
    Transplantation, 2003, Sep-15, Volume: 76, Issue:5

    Topics: Abnormalities, Multiple; Adolescent; Adult; Anti-Inflammatory Agents; Birth Weight; Diabetes Mellitu

2003
Pregnancy in kidney recipients under cyclosporine.
    Transplant international : official journal of the European Society for Organ Transplantation, 1992, Volume: 5 Suppl 1

    Topics: Azathioprine; Birth Weight; Creatinine; Cyclosporine; Female; Graft Rejection; Humans; Immunosuppres

1992
Studies in methods of investigating carbohydrate.
    Diabetologia, 1966, Volume: 2, Issue:3

    Topics: Adolescent; Adult; Birth Weight; Cortisone; Diet Therapy; Female; Fetal Death; Follow-Up Studies; Gl

1966
Adrenocorticosteroid therapy in pregnancy.
    American journal of obstetrics and gynecology, 1966, Dec-01, Volume: 96, Issue:7

    Topics: Adrenal Gland Diseases; Adult; Arthritis, Rheumatoid; Asthma; Birth Weight; Blood Group Incompatibil

1966
Low-dose corticoid therapy for anovulation: effect upon fetal weight.
    Obstetrics and gynecology, 1982, Volume: 60, Issue:3

    Topics: Adult; Anovulation; Birth Weight; Clomiphene; Estradiol Congeners; Female; Fetus; Humans; Infant, Ne

1982
Prenatal treatment of severe fetomaternal alloimmune thrombocytopenia.
    Transfusion medicine (Oxford, England), 1999, Volume: 9, Issue:4

    Topics: Antigens, Human Platelet; Autoantibodies; Birth Weight; Blood Specimen Collection; Blood Transfusion

1999
Effects of glucocorticoids during pregnancy on the outcome of the children directly after birth and in the long run.
    European journal of obstetrics, gynecology, and reproductive biology, 1977, Volume: 7, Issue:5

    Topics: Birth Weight; Child; Child, Preschool; Female; Growth; Humans; Infant; Infant, Newborn; Male; Predni

1977
Successful treatment of acute leukemia during pregnancy. Combination therapy in the third trimester.
    Archives of internal medicine, 1977, Volume: 137, Issue:1

    Topics: Adult; Birth Weight; Cytarabine; Drug Therapy, Combination; Female; Humans; Infant, Newborn; Karyoty

1977
Prednisone therapy and birth weight.
    Science (New York, N.Y.), 1979, Oct-05, Volume: 206, Issue:4414

    Topics: Adrenal Cortex Hormones; Birth Weight; Cortisone; Dose-Response Relationship, Drug; Female; Humans;

1979
Prednisone therapy and birth weight.
    Science (New York, N.Y.), 1979, Oct-05, Volume: 206, Issue:4414

    Topics: Birth Weight; Female; Humans; Prednisone; Pregnancy

1979
Prenatal exposure to prednisone in humans and animals retards intrauterine growth.
    Science (New York, N.Y.), 1978, Oct-27, Volume: 202, Issue:4366

    Topics: Animals; Birth Weight; Female; Fetus; Humans; Infant, Low Birth Weight; Infant, Newborn; Male; Mice;

1978
[Pregnancy after renal transplantation. 27 patients and review of the literature].
    Journal de gynecologie, obstetrique et biologie de la reproduction, 1992, Volume: 21, Issue:6

    Topics: Adult; Azathioprine; Birth Weight; Cesarean Section; Cyclosporine; Drug Therapy, Combination; Female

1992
Maternal and foetal outcome following Hodgkin's disease in pregnancy.
    British journal of cancer, 1992, Volume: 65, Issue:1

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Birth Weight; Case-Control Studies; Cesarean

1992
Outcome of pregnancy in women requiring corticosteroids for severe asthma.
    The Journal of allergy and clinical immunology, 1986, Volume: 78, Issue:2

    Topics: Adrenal Cortex Hormones; Adult; Asthma; Beclomethasone; Birth Weight; Female; Humans; Infant, Newbor

1986
Ring-1 chromosome, microcephalic dwarfism, and acute myeloid leukemia.
    American journal of diseases of children (1960), 1973, Volume: 126, Issue:2

    Topics: Anemia, Hemolytic; Anemia, Hypochromic; Birth Weight; Blood Cell Count; Bone Marrow Examination; Chi

1973
[Radioimmunological determination of somatotropic hormone secretion in premature subjects].
    Minerva pediatrica, 1974, May-19, Volume: 26, Issue:18

    Topics: Age Factors; Birth Weight; Body Weight; Child; Child, Preschool; Consciousness; Cortisone; Female; G

1974
Complications of pregnancy after renal transplantation including a report of spontaneous uterine rupture.
    Obstetrics and gynecology, 1973, Volume: 41, Issue:2

    Topics: Abortion, Spontaneous; Birth Weight; Female; Graft Rejection; Humans; Infant, Newborn; Infant, Prema

1973
Renal cadaver transplantation followed by successful pregnancies.
    Obstetrics and gynecology, 1974, Volume: 43, Issue:5

    Topics: Adult; Azathioprine; Birth Weight; Cadaver; Cesarean Section; Extraembryonic Membranes; Female; Glom

1974
Pregnancy and azathioprine in systemic lupus erythrmatosus.
    American journal of obstetrics and gynecology, 1974, Jan-01, Volume: 118, Issue:1

    Topics: Abnormalities, Drug-Induced; Adult; Azathioprine; Birth Weight; Female; Fetus; Humans; Lupus Erythem

1974
[Results of prednisone-glucose test in mothers delivering large fetuses].
    Ginekologia polska, 1972, Volume: 43, Issue:5

    Topics: Adult; Birth Weight; Diabetes Complications; Female; Fetus; Glucose; Humans; Infant, Newborn; Predia

1972
[Significance of abnormal fetal developments for the detection of prediabetic state].
    Zentralblatt fur Gynakologie, 1972, Jun-03, Volume: 94, Issue:22

    Topics: Birth Weight; Congenital Abnormalities; Diabetes Mellitus; Embryonic and Fetal Development; Female;

1972
[Erythropoiesis and corticotherapy in the first monthes of life].
    Annales de medecine interne, 1971, Volume: 122, Issue:12

    Topics: Adrenal Cortex Hormones; Anemia, Aplastic; Anemia, Hemolytic, Congenital; Birth Weight; Blood Transf

1971
[The significance of prediabetes of the mother for the fate of the child].
    Zeitschrift fur die gesamte innere Medizin und ihre Grenzgebiete, 1967, Volume: 22, Issue:7

    Topics: Adult; Birth Weight; Congenital Abnormalities; Female; Fetal Death; Glucose Tolerance Test; Humans;

1967
[The importance of the prednisone-glucose-test and the intravenous tolbutamide test in the detection of diabetes in the puerperium].
    Das Deutsche Gesundheitswesen, 1968, Oct-17, Volume: 23, Issue:42

    Topics: Adult; Birth Weight; Blood Glucose; Female; Glucose Tolerance Test; Humans; Prednisone; Pregnancy; P

1968