Page last updated: 2024-11-07

prednisone and Autosomal Recessive Emery-Dreifuss Muscular Dystrophy

prednisone has been researched along with Autosomal Recessive Emery-Dreifuss Muscular Dystrophy in 1 studies

Prednisone: A synthetic anti-inflammatory glucocorticoid derived from CORTISONE. It is biologically inert and converted to PREDNISOLONE in the liver.
prednisone : A synthetic glucocorticoid drug that is particularly effective as an immunosuppressant, and affects virtually all of the immune system. Prednisone is a prodrug that is converted by the liver into prednisolone (a beta-hydroxy group instead of the oxo group at position 11), which is the active drug and also a steroid.

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Dadgar, S1
Wang, Z1
Johnston, H1
Kesari, A1
Nagaraju, K1
Chen, YW1
Hill, DA1
Partridge, TA1
Giri, M1
Freishtat, RJ1
Nazarian, J1
Xuan, J1
Wang, Y1
Hoffman, EP1

Clinical Trials (3)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Phase IIb Randomized, Double-blind, Parallel Group, Placebo- and Active-controlled Study With Double-Blind Extension to Assess the Efficacy and Safety of Vamorolone in Ambulant Boys With Duchenne Muscular Dystrophy (DMD)[NCT03439670]Phase 2121 participants (Actual)Interventional2018-06-29Completed
A Phase II Open-Label, Multiple Dose Study to Assess the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Exploratory Efficacy of Vamorolone in Boys Ages 2 to <4 Years and 7 to <18 Years With Duchenne Muscular Dystrophy (DMD)[NCT05185622]Phase 254 participants (Anticipated)Interventional2022-03-21Recruiting
A Phase II Pilot Trial of Vamorolone vs. Placebo for the Treatment of Becker Muscular Dystrophy[NCT05166109]Phase 239 participants (Anticipated)Interventional2022-07-07Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Efficacy Measured by Time to Stand Test (TTSTAND) Velocity in Rises/Second Change From Baseline

Vamorolone at 6.0mg/kg/day vs. placebo group in change from baseline to the Week 24 assessment (NCT03439670)
Timeframe: 24 weeks

InterventionRises/Seconds (Mean)
Treatment Group 1-.007
Treatment Group 20.054

Other Studies

1 other study available for prednisone and Autosomal Recessive Emery-Dreifuss Muscular Dystrophy

ArticleYear
Asynchronous remodeling is a driver of failed regeneration in Duchenne muscular dystrophy.
    The Journal of cell biology, 2014, Oct-13, Volume: 207, Issue:1

    Topics: Animals; Anti-Inflammatory Agents; Cell Differentiation; Cells, Cultured; Dystrophin; Fibrosis; Huma

2014
Asynchronous remodeling is a driver of failed regeneration in Duchenne muscular dystrophy.
    The Journal of cell biology, 2014, Oct-13, Volume: 207, Issue:1

    Topics: Animals; Anti-Inflammatory Agents; Cell Differentiation; Cells, Cultured; Dystrophin; Fibrosis; Huma

2014
Asynchronous remodeling is a driver of failed regeneration in Duchenne muscular dystrophy.
    The Journal of cell biology, 2014, Oct-13, Volume: 207, Issue:1

    Topics: Animals; Anti-Inflammatory Agents; Cell Differentiation; Cells, Cultured; Dystrophin; Fibrosis; Huma

2014
Asynchronous remodeling is a driver of failed regeneration in Duchenne muscular dystrophy.
    The Journal of cell biology, 2014, Oct-13, Volume: 207, Issue:1

    Topics: Animals; Anti-Inflammatory Agents; Cell Differentiation; Cells, Cultured; Dystrophin; Fibrosis; Huma

2014
Asynchronous remodeling is a driver of failed regeneration in Duchenne muscular dystrophy.
    The Journal of cell biology, 2014, Oct-13, Volume: 207, Issue:1

    Topics: Animals; Anti-Inflammatory Agents; Cell Differentiation; Cells, Cultured; Dystrophin; Fibrosis; Huma

2014
Asynchronous remodeling is a driver of failed regeneration in Duchenne muscular dystrophy.
    The Journal of cell biology, 2014, Oct-13, Volume: 207, Issue:1

    Topics: Animals; Anti-Inflammatory Agents; Cell Differentiation; Cells, Cultured; Dystrophin; Fibrosis; Huma

2014
Asynchronous remodeling is a driver of failed regeneration in Duchenne muscular dystrophy.
    The Journal of cell biology, 2014, Oct-13, Volume: 207, Issue:1

    Topics: Animals; Anti-Inflammatory Agents; Cell Differentiation; Cells, Cultured; Dystrophin; Fibrosis; Huma

2014
Asynchronous remodeling is a driver of failed regeneration in Duchenne muscular dystrophy.
    The Journal of cell biology, 2014, Oct-13, Volume: 207, Issue:1

    Topics: Animals; Anti-Inflammatory Agents; Cell Differentiation; Cells, Cultured; Dystrophin; Fibrosis; Huma

2014
Asynchronous remodeling is a driver of failed regeneration in Duchenne muscular dystrophy.
    The Journal of cell biology, 2014, Oct-13, Volume: 207, Issue:1

    Topics: Animals; Anti-Inflammatory Agents; Cell Differentiation; Cells, Cultured; Dystrophin; Fibrosis; Huma

2014