prednisone and Autoimmune Demyelinating Disease, Peripheral studies

Prednisone: A synthetic anti-inflammatory glucocorticoid derived from CORTISONE. It is biologically inert and converted to PREDNISOLONE in the liver.
prednisone : A synthetic glucocorticoid drug that is particularly effective as an immunosuppressant, and affects virtually all of the immune system. Prednisone is a prodrug that is converted by the liver into prednisolone (a beta-hydroxy group instead of the oxo group at position 11), which is the active drug and also a steroid.

Research Excerpts

Excerpt	Relevance	Reference
"Intravenous steroid followed by oral prednisone was administered to patients with Guillain-Barré syndrome (five), acute transverse myelitis (three), and multiple sclerosis in acute relapse (seven)."	3.66	Possible beneficial effect of high-dose intravenous steroid therapy in acute demyelinating disease and transverse myelitis. ( Bosch, VV; Cook, SD; Dowling, PC, 1980)
"Prednisone was shown to cause a small but significant improvement over no treatment in scored neurological disability, some measures of computer-assisted sensory detection threshold, graded muscle strength, and some attributes of nerve conduction."	2.65	Prednisone improves chronic inflammatory demyelinating polyradiculoneuropathy more than no treatment. ( Bartleson, JD; Daube, JR; Dinapoli, RP; Dyck, PJ; Low, PA; Mokri, B; O'Brien, PC; Oviatt, KF; Swift, T; Windebank, AJ, 1982)
"Electrophysiological studies revealed demyelination in all patients and axonal damage in 94."	1.30	[Chronic inflammatory demyelinating polyradiculoneuropathy. Study of 18 cases]. ( Calia, LC; Gabbai, AA; Oliveira, AS, 1997)
"This patient later developed MCTD."	1.29	A HTLV-I carrier who showed various symptoms and antibodies of autoimmune diseases. ( Hashimoto, K; Hashimoto, M; Kawata, S; Mizuki, M; Nojima, J; Okamoto, Y; Sakata, K; Shibano, M; Tagawa, S; Takatsuki, K, 1993)
"Renal biopsy was consistent with focal segmental glomerulosclerosis."	1.29	A case of Guillain-Barré syndrome with focal segmental glomerulosclerosis. ( Axelsen, R; Boyle, R; Careless, D; Rigby, R, 1993)
"Two cases of patients with relapsing polyradiculoneuropathy with high protein level in cerebrospinal fluid are reported."	1.27	[Recurrent polyradiculoneuritis: report of 2 cases]. ( Callegaro, D; de Assis, JL; Marchiori, PE; Scaff, M; Zambon, AA, 1983)
" The first patient suffered from ulcerative colitis and developed Guillain-Barré syndrome when the steroid dosage was being tapered."	1.27	Appearance of Guillain-Barré syndrome in patients during corticosteroid treatment. ( Abramsky, O; Steiner, I; Wirguin, I, 1986)

Research

Studies (50)

Authors

Clinical Trials (2)

Trial Overview

Reviews

5 reviews available for prednisone and Autoimmune Demyelinating Disease, Peripheral

Trials

8 trials available for prednisone and Autoimmune Demyelinating Disease, Peripheral

Other Studies

37 other studies available for prednisone and Autoimmune Demyelinating Disease, Peripheral

Timeframe	Studies, this research(%)	All Research%
pre-1990	31 (62.00)	18.7374
1990's	14 (28.00)	18.2507
2000's	4 (8.00)	29.6817
2010's	1 (2.00)	24.3611
2020's	0 (0.00)	2.80

Authors	Studies
Nicolás-Sánchez, FJ	1
Piñol-Ripoll, G	1
Aróstegui-Gorospe, JI	1
Grau-Junyent, JM	1
Sarrat-Nuevo, RM	1
Melgarejo Moreno, PJ	1
Sibai, M	1
El Moutawakil, B	1
Chourkani, N	1
Bourezgui, M	1
Rafai, MA	1
Slassi, I	1
DEDEKAM, H	1
LONNUM, A	1
PALMER, KN	1
Couto, M	1
Conceição, I	1
de Carvalho, M	1
González Pérez, P	1
Serrano-Pozo, A	1
Franco-Macías, E	1
Montes-Latorre, E	1
Gómez-Aranda, F	1
Campos, T	1
Dowling, PC	1
Bosch, VV	1
Cook, SD	1
Kollias, GV	1
Clemmons, RM	1
Stetzer, ER	1
Walsh, MT	1
Beusse, DO	1
Vasilescu, C	1
Alexianu, M	1
Dan, A	1
Marchiori, PE	1
Scaff, M	1
Callegaro, D	1
Zambon, AA	1
de Assis, JL	1
Dyck, PJ	4
Pineda, A	1
Swanson, C	1
Low, P	1
Windebank, A	1
Daube, J	1
Tomonaga, M	1
O'Brien, PC	2
Oviatt, KF	2
Dinapoli, RP	2
Daube, JR	2
Bartleson, JD	2
Mokri, B	1
Swift, T	1
Low, PA	2
Windebank, AJ	1
Swanson, CJ	1
Lambert, EH	1
Külz, J	1
Bank, S	1
Kirschnick, HD	1
Dalakas, MC	1
Engel, WK	1
Colan, RV	1
Snead, OC	1
Oh, SJ	1
Benton, JW	1
Valbonesi, M	1
Mosconi, L	1
Garelli, S	1
Zerbi, D	1
Celano, I	1
Ferrer, X	1
Vital, C	1
Larriviere, M	1
Richard, S	1
Julien, J	1
Mizuki, M	1
Tagawa, S	1
Shibano, M	1
Okamoto, Y	1
Nojima, J	1
Sakata, K	1
Takatsuki, K	1
Kawata, S	1
Hashimoto, M	1
Hashimoto, K	1
Tanaka, M	1
Careless, D	1
Rigby, R	1
Axelsen, R	1
Boyle, R	1
Uncini, A	2
Sabatelli, M	1
Mignogna, T	1
Lugaresi, A	2
Liguori, R	1
Montagna, P	1
Van Doorn, PA	2
van der Meché, FG	1
Berger, JR	1
Gallo, B	1
Gómez, MB	1
Miravet, MJ	1
Vilaplana, R	1
Marín, AJ	1
Sánchez, J	1
Pérez, A	1
Piqueras, J	1
Calia, LC	1
Oliveira, AS	1
Gabbai, AA	1
Fredj, M	1
Ben Ghorbel, I	1
Jebloun, M	1
Gouider, R	1
Mrabet, A	1
De Luca, G	1
Iarlori, C	1
Marzoli, F	1
Di Iorio, A	1
Gambi, D	1
Ferriby, D	1
Stojkovic, T	1
De Seze, J	1
Hurtevent, JF	1
Vermersch, P	1
McQuillen, MP	1
Swick, HM	1
Bastron, JA	1
Groover, RV	1
Stevens, JC	1
Goulon, M	1
Combes, A	1
Chesneau, AM	1
Bournérias, I	1
Katznelson, D	1
Gross, S	1
Fève, AP	1
Smadja, D	1
Rancurel, G	1
Lèger, JM	1
Miller, RG	1
Antoine, JC	1
Michel, D	1
Kopp, N	1
Gonnaud, PM	1
Laurent, B	1
Ruderman, MI	1
Turkewitz, LJ	1
Steiner, I	1
Wirguin, I	1
Abramsky, O	1
Millette, TJ	1
Subramony, SH	1
Wee, AS	1
Harisdangkul, V	1
Provenzale, JM	1
Wertman, E	1
Argov, Z	1
Abrmasky, O	1
Mitchell, GW	1
Bosch, EP	1
Hart, MN	1
Dias-Tosta, E	1
Brasil, JP	1
Figueiredo, MA	1
Oken, BS	1
Mendell, JR	2
Kissel, JT	2
Kennedy, MS	2
Sahenk, Z	2
Grinvalsky, HT	2
Pittman, GL	2
Kyler, RS	2
Roelofs, RI	2
Whitaker, JN	2
Bertorini, TE	2
Hory, B	1
Blanc, D	1
Boillot, A	1
Panouse-Perrin, J	1

Trial	Phase	Enrollment	Study Type	Start Date	Status
InertiaLocoGraphy as a Biomarker of Immunoglobulin Therapy Efficacy in Chronic Inflammatory Demyelinating Polyradiculoneuropathy[NCT04529291]		0 participants (Actual)	Interventional	2022-04-16	Withdrawn (stopped due to The IP decided to stop.)
The Efficacy of High-Dose Intravenous Immunoglobulin in Chronic Inflammatory Demyelinating Polyneuropathy (CIDP)[NCT00001287]	Phase 2	60 participants	Interventional	1990-12-31	Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Article	Year
[A review on "cryptogenic neuropathy" with special reference to idiopathic chronic polyneuritis (author's transl)]. No to shinkei = Brain and nerve, 1981, Volume: 33, Issue:4 Topics: Adult; Chronic Disease; Female; Humans; Male; Neuromuscular Diseases; Polyneuropathies; Polyradiculo	1981
Treatment of patients with chronic inflammatory demyelinating polyneuropathy. Revue neurologique, 1996, Volume: 152, Issue:5 Topics: Anti-Inflammatory Agents; Chronic Disease; Demyelinating Diseases; Humans; Immunoglobulins, Intraven	1996
Guillain-Barré syndrome and chronic inflammatory demyelinating polyneuropathy: immune mechanisms and update on current therapies. Annals of neurology, 1995, Volume: 37 Suppl 1 Topics: Adult; Aged; Antigens, Bacterial; Autoantigens; Autoimmune Diseases; Campylobacter; Campylobacter In	1995
Neuropathies and myopathies complicating HIV infection. Journal of clinical apheresis, 1991, Volume: 6, Issue:2 Topics: Acquired Immunodeficiency Syndrome; Action Potentials; Adult; Antiviral Agents; Azathioprine; Combin	1991
[Chronic peripheral neuropathies with corticosensitive heredodegenerative aspects: 2 cases]. Revue neurologique, 1989, Volume: 145, Issue:6-7 Topics: Child; Chronic Disease; Follow-Up Studies; Hereditary Sensory and Motor Neuropathy; Humans; Male; Pe	1989

Article	Year
The Mayo Clinic experience with plasma exchange in chronic inflammatory-demyelinating polyneuropathy (CIDP). Progress in clinical and biological research, 1982, Volume: 106 Topics: Adult; Chronic Disease; Clinical Trials as Topic; Double-Blind Method; Female; Humans; Inflammation;	1982
Prednisone improves chronic inflammatory demyelinating polyradiculoneuropathy more than no treatment. Annals of neurology, 1982, Volume: 11, Issue:2 Topics: Adolescent; Adult; Chronic Disease; Clinical Trials as Topic; Demyelinating Diseases; Female; Humans	1982
Prednisone and plasma exchange improve suppressor cell function in chronic inflammatory demyelinating polyneuropathy. Journal of neuroimmunology, 1999, Mar-01, Volume: 95, Issue:1-2 Topics: Adolescent; Adult; Aged; Anti-Inflammatory Agents; Child; Chronic Disease; Combined Modality Therapy	1999
A.C.T.H. in Guillain-Barré syndrome. Lancet (London, England), 1978, Dec-02, Volume: 2, Issue:8101 Topics: Adrenocorticotropic Hormone; Clinical Trials as Topic; Drug Evaluation; Humans; Polyradiculoneuropat	1978
Suggestive preliminary evidence from controlled 3-month clinical trials that prednisone improves chronic inflammatory polyradiculoneuropathy. Transactions of the American Neurological Association, 1978, Volume: 103 Topics: Chronic Disease; Clinical Trials as Topic; Humans; Polyradiculoneuropathy; Prednisone	1978
[The use of corticosteroids in Guillain-Barré syndrome: study of 51 cases]. Arquivos de neuro-psiquiatria, 1986, Volume: 44, Issue:2 Topics: Clinical Trials as Topic; Dexamethasone; Female; Humans; Length of Stay; Male; Polyradiculoneuropath	1986
Plasma exchange and prednisone in Guillain-Barré syndrome: a controlled randomized trial. Neurology, 1985, Volume: 35, Issue:11 Topics: Adolescent; Adult; Aged; Clinical Trials as Topic; Female; Humans; Male; Middle Aged; Plasma Exchang	1985
Plasma exchange and prednisone in acute inflammatory polyradiculoneuropathy: a controlled randomized trial. Journal of clinical apheresis, 1985, Volume: 2, Issue:4 Topics: Acute Disease; Adolescent; Adult; Aged; Clinical Trials as Topic; Combined Modality Therapy; Female;	1985

Article	Year
Polyradiculoneuritis, cryopyrin-associated periodic syndromes, and familial Mediterranean fever. Neurologia (Barcelona, Spain), 2015, Volume: 30, Issue:5 Topics: Carrier Proteins; Colchicine; Cryopyrin-Associated Periodic Syndromes; Diagnosis, Differential; Fami	2015
[Neurological manifestations of chronic inflammatory bowel disease]. Revue neurologique, 2008, Volume: 164, Issue:10 Topics: Adult; Anti-Inflammatory Agents; Brain; Demyelinating Autoimmune Diseases, CNS; Female; Humans; Infl	2008
[STEROID TREATMENT IN POLYRADICULONEURITIS OF THE GUILLAIN-BARR'E SYNDROME TYPE]. Nordisk medicin, 1963, Aug-22, Volume: 70 Topics: Adrenocorticotropic Hormone; Cortisone; Polyradiculoneuropathy; Polyradiculopathy; Prednisone; Syndr	1963
POLYRADICULONEUROPATHY (GUILLAIN-BARR'E SYNDROME) TREATED WITH 6-MERCAPTOPURINE. Lancet (London, England), 1965, Apr-03, Volume: 1, Issue:7388 Topics: Child; Drug Therapy; Immunosuppressive Agents; Mercaptopurine; Polyradiculoneuropathy; Polyradiculop	1965
Steroid-responsive demyelinating motor neuropathy with conduction block associated with hepatitis C infection and treatment with interferon alpha. Journal of the peripheral nervous system : JPNS, 2006, Volume: 11, Issue:4 Topics: Anti-Inflammatory Agents; Antiviral Agents; Demyelinating Diseases; Evoked Potentials, Somatosensory	2006
Vincristine-induced acute neurotoxicity versus Guillain-Barré syndrome: a diagnostic dilemma. European journal of neurology, 2007, Volume: 14, Issue:7 Topics: Action Potentials; Adult; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin;	2007
Possible beneficial effect of high-dose intravenous steroid therapy in acute demyelinating disease and transverse myelitis. Neurology, 1980, Volume: 30, Issue:7 Pt 2 Topics: Acute Disease; Adolescent; Adrenocorticotropic Hormone; Adult; Demyelinating Diseases; Dose-Response	1980
Polyradiculoneuritis in a California sea lion. Journal of the American Veterinary Medical Association, 1984, Dec-01, Volume: 185, Issue:11 Topics: Animals; Anti-Infective Agents; Caniformia; Dexamethasone; Drug Combinations; Drug Therapy, Combinat	1984
Muscle hypertrophy and a syndrome of continuous motor unit activity in prednisone-responsive Guillain-Barré polyneuropathy. Journal of neurology, 1984, Volume: 231, Issue:5 Topics: Electromyography; Humans; Hypertrophy; Male; Middle Aged; Muscles; Neural Conduction; Neuromuscular	1984
[Recurrent polyradiculoneuritis: report of 2 cases]. Arquivos de neuro-psiquiatria, 1983, Volume: 41, Issue:2 Topics: Adolescent; Adult; Azathioprine; Cyclophosphamide; Female; HLA Antigens; Humans; Immunity; Male; Pol	1983
Prednisone-responsive hereditary motor and sensory neuropathy. Mayo Clinic proceedings, 1982, Volume: 57, Issue:4 Topics: Adolescent; Adult; Axons; Cerebrospinal Fluid Proteins; Charcot-Marie-Tooth Disease; Demyelinating D	1982
[Polyradiculoneuritis in childhood (Guillain-Barré syndrome]. Kinderarztliche Praxis, 1982, Volume: 50, Issue:7 Topics: Age Factors; Child; Child, Preschool; Female; Humans; Infant; Length of Stay; Male; Polyradiculoneur	1982
Chronic relapsing (dysimmune) polyneuropathy: pathogenesis and treatment. Annals of neurology, 1981, Volume: 9 Suppl Topics: Adolescent; Adult; Chronic Disease; Female; Humans; Immunoglobulin G; Immunoglobulin M; Immunosuppre	1981
Steroid-responsive polyneuropathy with subacute onset in childhood. The Journal of pediatrics, 1980, Volume: 97, Issue:3 Topics: Adolescent; Child; Child, Preschool; Diagnosis, Differential; Female; Humans; Male; Polyneuropathies	1980
Successful treatment by plasma exchange in Guillain-Barré syndrome with immune complexes. Vox sanguinis, 1980, Volume: 38, Issue:4 Topics: Adolescent; Cerebrospinal Fluid Proteins; Female; Humans; Plasma Exchange; Polyradiculoneuropathy; P	1980
Idiopathic CD4+ T-cell lymphocytopenia and subacute inflammatory demyelinating polyradiculoneuropathy. Neurology, 1995, Volume: 45, Issue:1 Topics: Anemia, Hemolytic; Arthralgia; CD4-Positive T-Lymphocytes; Demyelinating Diseases; Electrophysiology	1995
A HTLV-I carrier who showed various symptoms and antibodies of autoimmune diseases. Internal medicine (Tokyo, Japan), 1993, Volume: 32, Issue:6 Topics: Adult; Antibody Specificity; Autoantibodies; Autoimmune Diseases; Carrier State; Deltaretrovirus Ant	1993
Different mechanisms may operate in therapies for AIDP and multifocal motor neuropathy. Muscle & nerve, 1994, Volume: 17, Issue:10 Topics: Cyclophosphamide; Humans; Immunoglobulins, Intravenous; Motor Neuron Disease; Plasmapheresis; Polyra	1994
A case of Guillain-Barré syndrome with focal segmental glomerulosclerosis. American journal of nephrology, 1993, Volume: 13, Issue:2 Topics: Aged; Biopsy; Female; Glomerulosclerosis, Focal Segmental; Humans; Kidney Glomerulus; Plasmapheresis	1993
Chronic progressive steroid responsive axonal polyneuropathy: a CIDP vaariant or a primary axonal disorder? Muscle & nerve, 1996, Volume: 19, Issue:3 Topics: Adolescent; Adult; Aged; Axons; Biopsy; Chronic Disease; Demyelinating Diseases; Diagnosis, Differen	1996
Chronic inflammatory polyradiculoneuropathy associated with alopecia universalis. Muscle & nerve, 1998, Volume: 21, Issue:1 Topics: Alopecia; Anti-Inflammatory Agents; Autoimmune Diseases; Chronic Disease; Electromyography; Humans;	1998
[Paraparesis as the main manifestation of brucellosis]. Enfermedades infecciosas y microbiologia clinica, 1998, Volume: 16, Issue:3 Topics: Adolescent; Agglutination Tests; Anti-Bacterial Agents; Brucellosis; Cerebrospinal Fluid; Diplopia;	1998
[Chronic inflammatory demyelinating polyradiculoneuropathy. Study of 18 cases]. Arquivos de neuro-psiquiatria, 1997, Volume: 55, Issue:4 Topics: Adult; Aged; Aged, 80 and over; Child; Chronic Disease; Demyelinating Diseases; Female; Fluorescent	1997
[Polyradiculoneuritis and sarcoidosis]. La Revue de medecine interne, 1998, Volume: 19, Issue:10 Topics: Anti-Inflammatory Agents; Female; Follow-Up Studies; Humans; Magnetic Resonance Imaging; Middle Aged	1998
[Chronic polyradiculoneuritis disclosing sarcoidosis]. Revue neurologique, 2002, Volume: 158, Issue:3 Topics: Brain; Chronic Disease; Combined Modality Therapy; Female; Humans; Immunoglobulins, Intravenous; Imm	2002
[Polyradiculopathy associated with bullous pemphigoid (author's transl)]. La Nouvelle presse medicale, 1979, Jan-27, Volume: 8, Issue:5 Topics: Aged; Azathioprine; Dermatitis Herpetiformis; Diagnosis, Differential; Humans; Male; Pemphigoid, Bul	1979
Guillain-Barré syndrome following the use of thiabendazole. Acta paediatrica Scandinavica, 1978, Volume: 67, Issue:6 Topics: Child, Preschool; Female; Humans; Polyradiculoneuropathy; Prednisone; Thiabendazole	1978
Chronic inflammatory polyneuropathy associated with nephropathy and antifactor VIII antibody: improvement with intravenous immunoglobulin. Journal of neurology, neurosurgery, and psychiatry, 1992, Volume: 55, Issue:10 Topics: Aged; Autoantibodies; Chronic Disease; Combined Modality Therapy; Factor VIII; Female; Humans; Immun	1992
Relapsing polyneuritis following classic Miller Fisher syndrome. Journal of neurology, neurosurgery, and psychiatry, 1989, Volume: 52, Issue:6 Topics: Administration, Oral; Adult; Female; Humans; Polyradiculoneuropathy; Prednisone; Recurrence; Syndrom	1989
Current therapy of demyelinating neuropathies. The Mount Sinai journal of medicine, New York, 1985, Volume: 52, Issue:6 Topics: Adrenocorticotropic Hormone; Adult; Charcot-Marie-Tooth Disease; Child; Chronic Disease; Combined Mo	1985
Appearance of Guillain-Barré syndrome in patients during corticosteroid treatment. Journal of neurology, 1986, Volume: 233, Issue:4 Topics: Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Aged; Colitis, Ulcerative; Dexamethasone; Fema	1986
Systemic lupus erythematosus presenting with recurrent acute demyelinating polyneuropathy. European neurology, 1986, Volume: 25, Issue:6 Topics: Acute Disease; Adrenocorticotropic Hormone; Adult; Electromyography; Female; Humans; Lupus Erythemat	1986
Treatment modalities in Guillain-Barré syndrome. Hospital practice (Office ed.), 1987, Mar-15, Volume: 22, Issue:3 Topics: Animals; Cyclophosphamide; Humans; Plasma Exchange; Polyradiculoneuropathy; Prednisone; Respiration,	1987
Chronic inflammatory demyelinating polyradiculoneuropathy: features and prognostic factors with corticosteroid therapy. European neurology, 1988, Volume: 28, Issue:4 Topics: Action Potentials; Adult; Demyelinating Diseases; Dose-Response Relationship, Drug; Female; Follow-U	1988
Response to immunosuppressive therapy in patients with hereditary motor and sensory neuropathy and associated dysimmune neuromuscular disorders. European neurology, 1987, Volume: 27, Issue:3 Topics: Adult; Azathioprine; Female; Hereditary Sensory and Autonomic Neuropathies; Humans; Immunosuppressiv	1987
Plasma exchange and prednisone in GBS: evaluating efficacy. Neurology, 1986, Volume: 36, Issue:6 Topics: Humans; Plasma Exchange; Polyradiculoneuropathy; Prednisone	1986
Guillain-Barré syndrome following danazol and corticosteroid therapy for hereditary angioedema. The American journal of medicine, 1985, Volume: 79, Issue:1 Topics: Adolescent; Angioedema; Antigen-Antibody Complex; Complement C1 Inactivator Proteins; Danazol; Human	1985