prednisone has been researched along with Anemia, Fanconi in 12 studies
Prednisone: A synthetic anti-inflammatory glucocorticoid derived from CORTISONE. It is biologically inert and converted to PREDNISOLONE in the liver.
prednisone : A synthetic glucocorticoid drug that is particularly effective as an immunosuppressant, and affects virtually all of the immune system. Prednisone is a prodrug that is converted by the liver into prednisolone (a beta-hydroxy group instead of the oxo group at position 11), which is the active drug and also a steroid.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Graft-versus-host disease (GVHD) prophylaxis included cyclosporin A and prednisone." | 3.69 | Bone marrow transplantation in Fanconi anemia using matched sibling donors. ( DeLaat, C; Desantes, K; Friedman, DJ; Kohli-Kumar, M; Masterson, M; Morris, C; Mueller, R; Sambrano, J; Shahidi, NT; Yanik, G, 1994) |
| " After prednisone treatment for the syndrome, life-threatening intestinal ulceration and perforation developed, which was successfully treated." | 3.69 | Atypical PFAPA syndrome (periodic fever, aphthous stomatitis, pharyngitis, adenitis) in a young girl with Fanconi anemia. ( James-Herry, AG; Scimeca, PG; Weinblatt, ME, 1996) |
| " On the first arm of the study, IL-3 (Immunex Corp, Seattle, WA) was administered subcutaneously using a dose escalation regimen of 125 to 500 micrograms/m2/day in divided dosage at 12-hour intervals, coadministered with 1." | 1.29 | Failure of recombinant human interleukin-3 therapy to induce erythropoiesis in patients with refractory Diamond-Blackfan anemia. ( Berriman, AM; Feig, SA; Freedman, MH; Olivieri, NF; Shore, R; Valentino, L, 1994) |
| "A brother and sister with Fanconi's anemia, having typical skeletal deformity and characteristic chromosomal breaks in their lymphocytes and who followed the typical clinical course, with progressive bone marrow insufficiency beginning late in the first decade, are described." | 1.27 | Fanconi's anemia. A family study with 20-year follow-up including associated breast pathology. ( Jacobs, P; Karabus, C, 1984) |
| "An 11-year-old girl with Fanconi's anemia, who died of Corynebacterium septicemia, was found at autopsy to have a solitary, previously undiagnosed hepatocellular carcinoma (HCC)." | 1.27 | Hepatocellular carcinoma in an 11-year-old girl with Fanconi's anemia. Report of a case and review of the literature. ( Abbondanzo, SL; Gootenberg, JE; Klappenbach, RS; Manz, HJ, 1986) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (41.67) | 18.7374 |
| 1990's | 6 (50.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (8.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Voter, AF | 1 |
| Manthei, KA | 1 |
| Keck, JL | 1 |
| JEUNE, M | 1 |
| GERMAIN, D | 1 |
| HUMBERT, G | 1 |
| NIVELON, JL | 1 |
| Jacobs, P | 1 |
| Karabus, C | 1 |
| Bernini, JC | 1 |
| Carrillo, JM | 1 |
| Buchanan, GR | 1 |
| Kohli-Kumar, M | 1 |
| Morris, C | 1 |
| DeLaat, C | 1 |
| Sambrano, J | 1 |
| Masterson, M | 1 |
| Mueller, R | 1 |
| Shahidi, NT | 1 |
| Yanik, G | 1 |
| Desantes, K | 1 |
| Friedman, DJ | 1 |
| Olivieri, NF | 1 |
| Feig, SA | 1 |
| Valentino, L | 1 |
| Berriman, AM | 1 |
| Shore, R | 1 |
| Freedman, MH | 1 |
| Scimeca, PG | 1 |
| James-Herry, AG | 1 |
| Weinblatt, ME | 1 |
| Mulvihill, JJ | 1 |
| Ridolfi, RL | 1 |
| Schultz, FR | 1 |
| Borzy, MS | 1 |
| Haughton, PB | 1 |
| Meme, JS | 1 |
| Oduori, ML | 1 |
| Gripenberg, U | 1 |
| Splain, J | 1 |
| Berman, BW | 1 |
| Moldvay, J | 1 |
| Schaff, Z | 1 |
| Lapis, K | 1 |
| Abbondanzo, SL | 1 |
| Manz, HJ | 1 |
| Klappenbach, RS | 1 |
| Gootenberg, JE | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| The Use of Novel Therapies to Reconstitute Blood Cell Production and Promote Organ Performance Using Bone Marrow Failure as a Model: a Pilot, Phase I/II Study of the Amino Acid Leucine in the Treatment of Patients With Transfusion-Dependent Diamond Blackf[NCT01362595] | Phase 1/Phase 2 | 55 participants (Actual) | Interventional | 2013-06-30 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
"The primary outcome is the type of response observed at 9 months. Response to treatment can be one of the following:~Complete response (CR): Hb > 9 gm/dL and transfusion-independence as defined in DBA~Partial response (PR): Hb < 9 gm/dL and increased reticulocyte count to greater than baseline.~No response (NR): no change in transfusion requirements and no significant change reticulocyte count from baseline~Progression: worsening of disease as defined by the need for more frequent transfusions" (NCT01362595)
Timeframe: 9 Months
| Intervention | Participants (Count of Participants) | |||
|---|---|---|---|---|
| Complete Hematologic Response | Partial hematologic response | No hematologic response | Progression | |
| Leucine | 2 | 5 | 36 | 0 |
1 review available for prednisone and Anemia, Fanconi
| Article | Year |
|---|---|
Fanconi's aplastic anaemia: a case report of an affected African child and a review of the literature.
Topics: Anemia, Aplastic; Blood Transfusion; Child; Fanconi Anemia; Humans; Kenya; Male; Pedigree; Prednison | 1975 |
11 other studies available for prednisone and Anemia, Fanconi
| Article | Year |
|---|---|
A High-Throughput Screening Strategy to Identify Protein-Protein Interaction Inhibitors That Block the Fanconi Anemia DNA Repair Pathway.
Topics: Antineoplastic Agents; DNA Damage; DNA Helicases; DNA Repair; Drug Screening Assays, Antitumor; Fanc | 2016 |
[Associated androgen therapy and corticotherapy (Shahidi-Diamond method) in Fanconi's anemia].
Topics: Anemia; Anemia, Aplastic; Diamond; Fanconi Anemia; Hormone Replacement Therapy; Humans; Prednisone; | 1960 |
Fanconi's anemia. A family study with 20-year follow-up including associated breast pathology.
Topics: Anemia, Aplastic; Breast Diseases; Child; Fanconi Anemia; Female; Humans; Male; Methyltestosterone; | 1984 |
High-dose intravenous methylprednisolone therapy for patients with Diamond-Blackfan anemia refractory to conventional doses of prednisone.
Topics: Adolescent; Age of Onset; Anemia, Refractory; Anti-Infective Agents; Child, Preschool; Clinical Prot | 1995 |
Bone marrow transplantation in Fanconi anemia using matched sibling donors.
Topics: Abdomen; Bone Marrow Transplantation; Child; Child, Preschool; Chronic Disease; Cyclophosphamide; Cy | 1994 |
Failure of recombinant human interleukin-3 therapy to induce erythropoiesis in patients with refractory Diamond-Blackfan anemia.
Topics: Adolescent; Bone Marrow; Child; Child, Preschool; Erythrocyte Count; Erythropoiesis; Erythropoietin; | 1994 |
Atypical PFAPA syndrome (periodic fever, aphthous stomatitis, pharyngitis, adenitis) in a young girl with Fanconi anemia.
Topics: Cecal Diseases; Child; Child, Preschool; Familial Mediterranean Fever; Fanconi Anemia; Female; Human | 1996 |
Hepatic adenoma in Fanconi anemia treated with oxymetholone.
Topics: Adolescent; Adult; Anemia, Aplastic; Autopsy; Carcinoma, Hepatocellular; Child; Fanconi Anemia; Fema | 1975 |
Cyclosporin A treatment for Diamond-Blackfan anemia.
Topics: Adolescent; Bone Diseases; Bone Diseases, Metabolic; Child; Child, Preschool; Cyclosporine; Drug Adm | 1992 |
Hepatocellular carcinoma in Fanconi's anemia treated with androgen and corticosteroid.
Topics: Adrenal Cortex Hormones; Androgens; Blood Transfusion; Carcinoma, Hepatocellular; Child; Fanconi Ane | 1991 |
Hepatocellular carcinoma in an 11-year-old girl with Fanconi's anemia. Report of a case and review of the literature.
Topics: Anemia, Aplastic; Autopsy; Carcinoma, Hepatocellular; Child; Fanconi Anemia; Female; Humans; Liver N | 1986 |