prednisone has been researched along with Anankastic Personality in 3 studies
Prednisone: A synthetic anti-inflammatory glucocorticoid derived from CORTISONE. It is biologically inert and converted to PREDNISOLONE in the liver.
prednisone : A synthetic glucocorticoid drug that is particularly effective as an immunosuppressant, and affects virtually all of the immune system. Prednisone is a prodrug that is converted by the liver into prednisolone (a beta-hydroxy group instead of the oxo group at position 11), which is the active drug and also a steroid.
Excerpt | Relevance | Reference |
---|---|---|
" He received six months oral steroid (prednisone) treatment in 20 mg daily dose resulting in symptomatic depression." | 3.72 | Symptomatic depression after long-term steroid treatment: a case report. ( Ros, LT, 2004) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 2 (66.67) | 18.2507 |
2000's | 1 (33.33) | 29.6817 |
2010's | 0 (0.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Ros, LT | 1 |
Garvey, MA | 1 |
Swedo, SE | 1 |
Grabe, HJ | 1 |
Freyberger, HJ | 1 |
Maier, W | 1 |
Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
---|---|---|---|---|---|---|---|
Antibiotic Treatment Trial for the PANDAS/PANS Phenotype[NCT01617083] | Phase 2 | 47 participants (Actual) | Interventional | 2012-05-31 | Completed | ||
[information is prepared from clinicaltrials.gov, extracted Sep-2024] |
The CYBOCS is a clinician rated, semi-structured interview for rating the severity of OCD (Scahill, et al., 1997). Total scores range from 0 to 50, with higher scores representing greater severity. The total score is comprised of two subscores, obsessions and compulsions, each with a range of 0-25. (NCT01617083)
Timeframe: Before and after 4 week randomization
Intervention | units on a scale (Mean) | |
---|---|---|
Baseline | After 4 week randomization | |
Azithromycin | 29.49 | 20.53 |
Placebo | 28.43 | 23.45 |
The CGI-S scale is a 7-point clinician rating of severity of psychopathology. Severity ratings range from 1 (no illness) to 7 (extremely severe). This instrument has been successfully used in treatment studies (Cook, et al., 2001; Storch, et al., 2007). (NCT01617083)
Timeframe: Before and after 4 week randomization
Intervention | units on a scale (Mean) | |
---|---|---|
Baseline | After 4 week randomization | |
Azithromycin | 5.24 | 4.06 |
Placebo | 5.00 | 4.93 |
The Screen for Childhood Anxiety-Related Emotional Disorders (SCARED) is a 41-item parent and participant-completed tool used to measure symptoms of anxiety, including the most common symptoms of panic/somatic, generalized anxiety, separation anxiety, social phobia, and school phobia. Scores range from 0-82, with higher scores indicating more severe symptoms.The child and parent versions of the SCARED have moderate parent-child agreement and good internal consistency, test-retest reliability, and discriminant validity; it is also sensitive to treatment response (Birmaher et al. 1999). The target population for this rating is 8-18 years of age (Birmaher et al. 1997). The parent and child version of the SCARED were administered before and after week 4 randomization. This measure is not validated for use in 4-7 year olds. (NCT01617083)
Timeframe: Before and after 4 week randomization
Intervention | units on a scale (Mean) | |
---|---|---|
Baseline | After 4 week randomization | |
Azithromycin | 31.82 | 30.88 |
Placebo | 20.43 | 21.97 |
3 other studies available for prednisone and Anankastic Personality
Article | Year |
---|---|
Symptomatic depression after long-term steroid treatment: a case report.
Topics: Adult; Antidepressive Agents; Depression; Dose-Response Relationship, Drug; Glucocorticoids; Hepatit | 2004 |
Sydenham's chorea. Clinical and therapeutic update.
Topics: Basal Ganglia; Child; Chorea; Female; Humans; Immunoglobulins, Intravenous; Immunotherapy; Male; Obs | 1997 |
Obsessive-compulsive symptom exacerbation following cortisone treatment.
Topics: Adult; Anti-Inflammatory Agents; Colitis; Cortisone; Humans; Male; Obsessive-Compulsive Disorder; Pr | 1998 |