Page last updated: 2024-11-07

prednisone and Alopecia

prednisone has been researched along with Alopecia in 91 studies

Prednisone: A synthetic anti-inflammatory glucocorticoid derived from CORTISONE. It is biologically inert and converted to PREDNISOLONE in the liver.
prednisone : A synthetic glucocorticoid drug that is particularly effective as an immunosuppressant, and affects virtually all of the immune system. Prednisone is a prodrug that is converted by the liver into prednisolone (a beta-hydroxy group instead of the oxo group at position 11), which is the active drug and also a steroid.

Alopecia: Absence of hair from areas where it is normally present.

Research Excerpts

ExcerptRelevanceReference
" Chlorambucil may hold advantages over the immunosuppressive drugs normally recommended in this condition, azathioprine and cyclophosphamide, as it appears less liable to cause important marrow suppression and, unlike cyclophosphamide is not associated with alopecia and haemorrhagic cystitis."7.65Treatment of patients with systemic lupus erythematosus including nephritis with chlorambucil. ( Dunnill, MS; Halley, W; Holt, JM; Oliver, DO; Snaith, ML; Stephenson, AC, 1973)
"To evaluate the efficacy and safety of methotrexate (MTX) used alone or combined with low- to moderate-dose oral corticosteroids (OC) for treating severe AA (totalis, universalis and severe multifocal)."5.43Efficacy and Safety of Methotrexate Combined with Low- to Moderate-Dose Corticosteroids for Severe Alopecia Areata. ( Anuset, D; Bernard, P; Perceau, G; Reguiai, Z, 2016)
"Oral prednisone was given at an initial dosage of 10 mg/d in one patient and 20 mg/d in 15 patients."5.33The use of methotrexate alone or in combination with low doses of oral corticosteroids in the treatment of alopecia totalis or universalis. ( Joly, P, 2006)
"Seventy-five female patients suffering from advanced breast cancer were treated with toilet mastectomy, radiotherapy and oophorectomy (if premenopausal) or tamoxifen therapy (if postmenopausal) as well as chemotherapy with cyclophosphamide, methotrexate, 5-fluorouracil and prednisone."3.68Toxicity and side-effects of combination chemohormonal therapy of advanced breast cancer. ( Dandapat, MC; Mohapatro, SK; Padhi, NC, 1992)
"Forty-seven adults with advanced malignant lymphoma (the majority in stage IV) were treated with a combination of cyclophosphamide, hydroxyldaunorubicin (Adriamycin), vincristine (Oncovin), prednisone, and bleomycin (CHOP-Bleo)."3.65Combination chemotherapy ("CHOP-Bleo") in advanced (non-Hodgkin) malignant lymphoma. ( Bodey, GP; Burgess, MA; Cabanillas, F; Freireich, EJ; McKelvey, EM; Rodriguez, V; Valdivieso, M, 1977)
" Chlorambucil may hold advantages over the immunosuppressive drugs normally recommended in this condition, azathioprine and cyclophosphamide, as it appears less liable to cause important marrow suppression and, unlike cyclophosphamide is not associated with alopecia and haemorrhagic cystitis."3.65Treatment of patients with systemic lupus erythematosus including nephritis with chlorambucil. ( Dunnill, MS; Halley, W; Holt, JM; Oliver, DO; Snaith, ML; Stephenson, AC, 1973)
"Twenty-five patients with advanced metastatic breast cancer were treated with the combination of methotrexate 60 mg/M(2) and 5-fluorouracil 700 mg/M(2) intravenously on the first and eighth days, and cyclophosphamide 100 mg/M(2) and prednisone 40 mg/M(2) by mouth daily for the first 14 days of a 28-day cycle."3.65Cyclical combination chemotherapy for advanced breast carcinoma. ( Canellos, GP; Chabner, BA; Devita, VT; Gold, GL; Schein, PS; Young, RC, 1974)
" Prednisolone dosage was gradually tapered to 10 mg/d at 6 months, when cyclophosphamide was replaced by azathioprine (2 mg/kg/d p."2.69Treatment of membranous lupus nephritis with nephrotic syndrome by sequential immunosuppression. ( Chan, KW; Chan, TM; Hao, WK; Lai, KN; Li, FK; Lui, SL; Tang, S, 1999)
"Leukopenia was the dose-limiting toxicity with all three regimens."2.64Combination chemotherapy and adriamycin in patients with advanced breast cancer. A Southwest Oncology Group study. ( Bonnet, JD; Braine, H; Costanzi, JJ; George, SL; Hoogstraten, B; Rivkin, SE; Samal, B; Thigpen, T, 1976)
"To date, all available therapies for prostate cancer are plagued by adverse effects."2.41Complications of chemotherapy for prostate cancer. ( Beer, TM; Bubalo, JS, 2001)
"To evaluate the efficacy and safety of methotrexate (MTX) used alone or combined with low- to moderate-dose oral corticosteroids (OC) for treating severe AA (totalis, universalis and severe multifocal)."1.43Efficacy and Safety of Methotrexate Combined with Low- to Moderate-Dose Corticosteroids for Severe Alopecia Areata. ( Anuset, D; Bernard, P; Perceau, G; Reguiai, Z, 2016)
"Satoyoshi syndrome is a rare multisystemic disease of presumed autoimmune etiology characterized by progressive painful intermittent muscle spasms, diarrhea frequently associated with malabsorption, alopecia, skeletal abnormalities and endocrine disorders with a poor long-term prognosis due to early crippling."1.35[Satoyoshi syndrome: report of one case]. ( Castiglioni, C; Díaz, A; Hernández, C; Mericq, V; Moënne, K; Salvador, F, 2009)
"Oral prednisone was given at an initial dosage of 10 mg/d in one patient and 20 mg/d in 15 patients."1.33The use of methotrexate alone or in combination with low doses of oral corticosteroids in the treatment of alopecia totalis or universalis. ( Joly, P, 2006)
"The VKH syndrome has been reported to occur in association with other autoimmune disorders."1.32Vogt-Koyanagi-Harada syndrome and ulcerative colitis. ( Federman, DG; Judson, PH; Kirsner, RS; Kravetz, JD; Ruser, CB, 2004)
"Satoyoshi syndrome is a rare disorder of unknown etiology characterized by progressive, painful intermittent muscle spasms, severe skeletal abnormalities mimicking a skeletal dysplasia, malabsorption, alopecia, and amenorrhea."1.30Radiological and orthopedic abnormalities in Satoyoshi syndrome. ( Ehlayel, MS; Haymon, M; Lacassie, Y; Willis, RB, 1997)
"infusions in the treatment of B cell chronic lymphocytic leukemia (B-CLL) in patients 55 years old and younger."1.302-Chlorodeoxyadenosine (Cladribine) in the treatment of patients with chronic lymphocytic leukemia 55 years old and younger. ( Błasińska-Morawiec, M; Błoński, JZ; Robak, T; Skotnicki, AB; Urbańska-Ryś, H, 1999)
"Thirty-eight patients with advanced Hodgkin's disease were treated with a combination of cyclophosphamide, vinblastine, procarbazine, and prednisone (CVPP)."1.26Combinaed chemotherapy with cyclophosphamide, vinblastine, procarbazine, and prednisone (CVPP) for patients with advanced Hodgkin's disease. An alternative program to MOPP. ( Bloomfield, CD; Fortuny, I; Kennedy, BJ; Vosika, G; Weiss, RB, 1976)
"Seventy-two women with metastatic breast cancer were treated with multiple-agent chemotherapy."1.26Combination chemotherapy in the treatment of advanced breast cancer. ( Dao, TL; Nemoto, T; Rosner, D, 1976)

Research

Studies (91)

TimeframeStudies, this research(%)All Research%
pre-199052 (57.14)18.7374
1990's11 (12.09)18.2507
2000's16 (17.58)29.6817
2010's9 (9.89)24.3611
2020's3 (3.30)2.80

Authors

AuthorsStudies
Zhou, X1
Wang, Y1
Li, X1
Zhuo, XW1
Fang, F1
Gong, S1
Feng, WX1
Ding, CH1
Xiang, X1
Ge, M1
Zhang, N1
Li, JW1
Marsh, RL1
Spohn, GP1
Kaffenberger, JA1
Avilés, A1
Nambo, MJ1
Neri, N1
Watanabe-Okada, E1
Inazumi, T1
Matsukawa, H1
Ohyama, M1
Flinn, IW1
van der Jagt, R1
Kahl, BS1
Wood, P1
Hawkins, TE1
Macdonald, D1
Hertzberg, M1
Kwan, YL1
Simpson, D1
Craig, M1
Kolibaba, K1
Issa, S1
Clementi, R1
Hallman, DM1
Munteanu, M1
Chen, L1
Burke, JM1
Manríquez, J1
Niklitschek, S1
Anuset, D1
Perceau, G1
Bernard, P1
Reguiai, Z1
Niu, Y1
Shi, YK1
He, XH1
Feng, FY1
Zhou, LQ1
Gu, DZ1
Castiglioni, C1
Díaz, A1
Moënne, K1
Mericq, V1
Salvador, F1
Hernández, C1
El Halim Mohamed Abu Hamar, A1
Mansour, S1
El Shebiney, M1
El Bary, NM1
Sadaka, E1
Maria, A1
Zegarska, B1
Kallas, D1
Schwartz, RA1
Czajkowski, R1
Uchanska, G1
Placek, W1
Fernández-Morano, T1
Aguilar-Bernier, M1
Del Boz, J1
Fúnez-Liébana, R1
Goñi Esarte, S1
Arín Letamendía, A1
Vila Costas, JJ1
Jiménez Pérez, FJ1
Ruiz-Clavijo García, D1
Carrascosa Gil, J1
Almendral López, ML1
Sato-Kawamura, M1
Aiba, S1
Tagami, H1
Douri, T1
Chawaf, AZ1
Alrefaee, BA1
SCHROPL, E1
SCHROPL, V1
FUNK, CF1
ALVERDES, L1
SCHMIDT, G1
HARNACK, K1
EL-NASR, HS1
EL-HEFNAWI, H1
DEWAR, HA1
PEASTON, MJ1
KOUBA, K1
STAFOVA, J1
RUSSELL, B1
Imai, Y1
Isoda, K1
Ito, E1
Hakamada, A1
Yamanishi, K1
Mizutani, H1
Kamat, D1
Petry, L1
Berry, S1
Federman, DG1
Kravetz, JD1
Ruser, CB1
Judson, PH1
Kirsner, RS1
Pournaras, CC1
Masouye, I1
Piletta, P1
Piguet, V2
Saurat, JH2
French, LE1
Joly, P1
Sampson, JE1
Harmon, ML1
Cushman, M1
Krawitt, EL1
Huang, HQ1
Lin, XB1
Pan, ZH1
Bu, Q1
Gao, Y1
Wang, BF1
Cai, QQ1
Xia, ZJ1
Xu, RH1
Jiang, WQ1
Guan, ZZ1
Bartels, H1
Schneider, B1
Feller, AC1
Pinnamaneni, K1
Yap, HY1
Buzdar, AU1
Distefano, A1
Blumenschein, GR1
Bogusławska-Jaworska, J1
Kościelniak, E1
Sroczyńska, M1
Sońta-Jakimczyk, D1
Armata, J1
Balwierz, W1
Ciepielewska, D1
Kaczmarek-Kanold, M1
Ochocka, M1
Radwańska, U1
Waibel, PJ1
Jungi, WF1
Senn, HJ1
Hirshaut, Y1
Kesselheim, H1
Vaughn, CB1
Maniscalco-Greb, E1
Lockhard, C1
Groshko, G1
Enochs, K1
Duffin, H1
Demitrish, M1
Nashel, DJ1
Ulmer, CC1
Cunningham, ET1
Demetrius, R1
Frieden, IJ1
Emery, HM1
Irvine, AR1
Good, WV1
Holm, AL1
Bowers, KE1
McMeekin, TO1
Gaspari, AA1
Kossard, S1
Lee, MS1
Wilkinson, B1
Haymon, M1
Willis, RB1
Ehlayel, MS1
Lacassie, Y1
Berger, JR1
Gallo, B1
Allbritton, J1
Simmons-O'Brien, E1
Hutcheons, D1
Whitmore, SE1
Fierro, MT1
Quaglino, P1
Savoia, P1
Verrone, A1
Bernengo, MG1
Robak, T1
Błoński, JZ1
Urbańska-Ryś, H1
Błasińska-Morawiec, M1
Skotnicki, AB1
Chan, TM1
Li, FK1
Hao, WK1
Chan, KW1
Lui, SL1
Tang, S1
Lai, KN1
Lishner, M1
Manor, Y1
Kitay-Cohen, Y1
Avishay, AE1
Beer, TM1
Bubalo, JS1
Leblond, V1
Lévy, V1
Maloisel, F1
Cazin, B1
Fermand, JP1
Harousseau, JL1
Remenieras, L1
Porcher, R1
Gardembas, M1
Marit, G1
Deconinck, E1
Desablens, B1
Guilhot, F1
Philippe, G1
Stamatoullas, A1
Guibon, O1
Friedli, A1
Pessina, PA1
Chavaz, P1
Economopoulos, T1
Dimopoulos, MA1
Mellou, S1
Pavlidis, N1
Samantas, E1
Nicolaides, C1
Tsatalas, C1
Papadopoulos, A1
Papageogriou, E1
Papasavvas, P1
Fountzilas, G1
Hidalgo-Tenorio, C1
Sabio, JM1
Jiménez-Alonso, J1
Rodriguez, V1
Cabanillas, F1
Burgess, MA1
McKelvey, EM1
Valdivieso, M1
Bodey, GP1
Freireich, EJ1
Hohmeister, R1
Waldburger, M1
Hughes, GR1
Unger, WP3
Schemmer, RJ1
Hoogstraten, B1
George, SL1
Samal, B1
Rivkin, SE1
Costanzi, JJ1
Bonnet, JD1
Thigpen, T1
Braine, H1
Bloomfield, CD1
Weiss, RB1
Fortuny, I1
Vosika, G1
Kennedy, BJ1
Rosner, D1
Nemoto, T1
Dao, TL1
von Lieven, H1
Heinze, HG1
Lampert, F1
Smyth, CJ1
Bartholomew, BA1
Mills, DM1
Steigerwald, JC1
Strong, SJ1
Recart, S1
Mohapatro, SK1
Dandapat, MC1
Padhi, NC1
Rothfield, NF1
White, WB1
Shornick, JK1
Grant-Kels, JM1
Ballow, M1
Leonard, RC2
Lucraft, HH2
Proctor, SJ1
Allan, NC1
Dawson, AA1
McGillivray, JB1
Parker, AC1
Prescott, RJ1
van Joost, T1
Stolz, E1
Habets, W1
Notowicz, A1
Carter, SK1
McDonald, J1
Murphy, AV1
Arneil, GC1
Pambor, M1
Rosner, J1
Kisielewska, W1
Koranda, FC1
Dehmel, EM1
Kahn, G1
Penn, I1
Fairley, GH1
Freeman, JE1
Krain, LS1
Landau, JW1
Newcomer, VD1
Chiu, J1
McLaine, PN1
Drummond, KN2
Snaith, ML1
Holt, JM1
Oliver, DO1
Dunnill, MS1
Halley, W1
Stephenson, AC1
Ahmann, DL1
Bisel, HF1
Hahn, RG1
Smith, KL1
Johnson, D1
Hustu, O1
Pratt, C1
Fleming, I1
Holton, C1
Canellos, GP1
Devita, VT1
Gold, GL1
Chabner, BA1
Schein, PS1
Young, RC1
Cassady, JR1
Jaffe, N1
Piro, AJ1
Wilson, RE1
Hall, TC1
Aliapoulios, MA1
Nevinny, HB1
Moore, FD1
Bairstow, B1
Hardisty, RM1
McElwain, TJ1
Darby, CW1
Vamberová, M1
Dietz, O1
Hillman, DA1
Marchessault, JH1
Feldman, W1
Kononenko, OG1
Iudkina, LN1
Fernbach, DJ1
Griffith, KM1
Haggard, ME1
Holcomb, TM1
Sutow, WW1
Vietti, TJ1
Windmiller, J1
Kostanecki, W1
Kwiatkowska, E1
Zborzil, J1

Clinical Trials (4)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
An Open-Label, Randomized, Parallel-Group Study of Bendamustine Hydrochloride and Rituximab (BR) Compared With Rituximab, Cyclophosphamide, Vincristine, and Prednisone (R-CVP) or Rituximab, Cyclophosphamide, Doxorubicin, Vincristine, and Prednisone (R-CHO[NCT00877006]Phase 3447 participants (Actual)Interventional2009-04-30Completed
Isatuximab and Bendamustine in Systemic Light Chain Amyloidosis[NCT04943302]Phase 20 participants (Actual)Interventional2022-09-30Withdrawn (stopped due to PI left institution. Study not moving forward in her absence.)
A Randomized Phase II Trial Comparing BeEAM With BEAM as Conditioning Regimen for Autologous Stem Cell Transplantation (ASCT) in Lymphoma Patients (BEB-trial)[NCT02278796]Phase 2108 participants (Actual)Interventional2015-04-30Completed
A Prospective, Open, Randomized Controlled, Multi-center Phase III Clinical Trial Comparing High-dose Epirubicin and Standard-dose Epirubicin in R±CEOP in Newly Diagnosed Young Patients With Medium/High-risk Diffuse Large B-cell Lymphoma[NCT03151044]Phase 3408 participants (Anticipated)Interventional2016-07-31Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Change From Baseline to End of Treatment in the Global Health Status Score of the European Organization for Research and Treatment of Cancer (EORTC) 30-item Core Quality of Life Questionnaire (QLQ-C30)

EORTC QLQ-C30 is a 30-item questionnaire to assess the overall quality of life in cancer patients. EORTC QLQ-C30 includes functional scales (physical, role, cognitive, emotional, and social), global health status, symptom scales (fatigue, pain, nausea/vomiting), and other (dyspnoea, appetite loss, insomnia, constipation/diarrhea, and financial difficulties). This outcome reports the global health status on a scale of 0-100 with a high score for the global health status/QOL represents a high quality of life. (NCT00877006)
Timeframe: Day 1 (prior to treatment), 32 weeks

Interventionunits on a scale (Mean)
Bendamustine and Rituximab (BR)3.6
R-CHOP/R-CVP-5.1

Kaplan-Meier Estimate for Duration of Response (DOR)

DOR was defined as the time from first response (CR or PR) to disease progression or relapse, or death due to any cause. (NCT00877006)
Timeframe: Day 1 up to 5.6 years (Treatment Period + Long-Term Follow-up Period)

Interventionmonths (Median)
Bendamustine and Rituximab (BR)26.5
R-CHOP/R-CVP32.1

Kaplan-Meier Estimate for Event-free Survival (EFS)

"EFS was defined as the time from randomization to treatment failure, disease progression or relapse, other malignancies, or death from any cause, whichever occurred first.~Treatment failure was defined as failure to achieve a CR or PR after 6 cycles of treatment. If a patient failed to achieve CR or PR by the time of data analysis or early withdrawal, the treatment failure date was set at 126 days (6 cycles of treatment) after randomization or the new anticancer treatment date, whichever is earlier." (NCT00877006)
Timeframe: Day 1 up to 5.6 years (Treatment Period + Long-Term Follow-up Period)

Interventionmonths (Median)
Bendamustine and Rituximab (BR)31.8
R-CHOP/R-CVP32.6

Kaplan-Meier Estimate for Progression-free Survival (PFS)

PFS was defined as the time from randomization to disease progression or relapse, or death from any cause, whichever occurred first. (NCT00877006)
Timeframe: Day 1 up to 5.6 years (Treatment Period + Long-Term Follow-up Period)

Interventionmonths (Median)
Bendamustine and Rituximab (BR)31.8
R-CHOP/R-CVP33.4

Overall Survival (OS)

OS was defined as the time from randomization to death from any cause. (NCT00877006)
Timeframe: Day 1 up to 5.6 years (Treatment Period + Long-Term Follow-up Period)

Interventionmonths (Median)
Bendamustine and Rituximab (BR)65.0
R-CHOP/R-CVP64.1

Participants With Disease Progression, Relapse or Death At the End of the Treatment Period or the Long-Term Follow-up Period

"Relapsed disease (after CR) and progressive disease (PD) (after PR or SD):~Lymph nodes were considered abnormal if the long axis was greater than 1.5 cm. Lymph nodes with a long axis of 1.1 to 1.5 cm were considered abnormal if its short axis was greater than 1.0 cm.~In patients with no prior history of pulmonary lymphoma, new lung nodules identified by CT require histologic confirmation.~>= 50% increase from nadir in sum of the products of the greatest diameters (SPD) of any previously involved nodes, or in a single involved node, or the size of other lesions (eg, splenic or hepatic nodules). To be considered progressive disease, a lymph node with a diameter of the short axis of less than 1.0 cm must have increased by 2: 50% and to a size of 1.5 cm by 1.5 cm, or more than 1.5 cm in the long axis~other conditions as specified in the protocol" (NCT00877006)
Timeframe: Treatment Period: 18-32 weeks Long-Term Follow-up Period: up to 5 years after the Treatment Period

InterventionParticipants (Count of Participants)
Bendamustine and Rituximab (BR)36
R-CHOP/R-CVP30

Percentage of Participants With Complete Response (CR) at End of Treatment Period

CR=complete disappearance of all detectable clinical evidence of disease and disease-related symptoms, if present pretherapy; protocol-specified positron emission tomography (PET) scan assessment criteria; (if the spleen and/or liver were enlarged on the basis of physical examination and/or anatomic imaging before treatment) the liver and/or spleen were considered normal size on physical examination and by anatomic imaging after therapy, with disappearance of all nodules related to lymphoma; (if the bone marrow was involved by lymphoma before treatment) the infiltrate must have cleared on subsequent bone marrow biopsies. (NCT00877006)
Timeframe: 6 to 8 21 or 28-day cycles (18-32 weeks)

Interventionpercentage of participants (Number)
Bendamustine and Rituximab (BR)31
R-CHOP/R-CVP25

Percentage of Participants With Overall Response at End of Treatment Period

Overall Response=participants with Complete Remission (CR) + those with Partial Remission (PR). CR=see Outcome Measure 1 for details. PR= at least a 50% decrease in the sum of the product of the greatest diameters (SPD) of up to 6 of the largest dominant nodes/masses; at least a 50% decrease in the SPD of hepatic and splenic nodules in their greatest transverse diameter; no increase in the size of the liver, spleen, and other nodes; no measurable disease in organs other than the liver or spleen; no new sites of disease; protocol-specified PET scan and bone marrow criteria. (NCT00877006)
Timeframe: 6 to 8 21 or 28-day cycles (18-32 weeks)

Interventionpercentage of participants (Number)
Bendamustine and Rituximab (BR)97
R-CHOP/R-CVP91

Clinically Significant Abnormal Vital Signs

(NCT00877006)
Timeframe: 32 weeks (conducted at screening, Day 1 of each cycle, and end-of-treatment visit)

,
Interventionparticipants (Number)
Heart Rate >=120 and ↑ >=15 bpmHeart Rate <=50 and ↓ >=15 bpmSystolic Blood Pressure(BP) >=180 and ↑ >=20 mm HgSystolic BP <=90 and ↓ >=20 mm HgDiastolic BP >=105 and ↑ from Baseline >=15 mm HgDiastolic BP <=50 and ↓ from Baseline >=15 mm Hg
Bendamustine and Rituximab (BR)022612
R-CHOP/R-CVP122222

Eastern Cooperative Oncology Group (ECOG) Performance Status at the End of Treatment Period

Participants' ECOG Performance Status was evaluated at the end of treatment as improved, stayed the same, or worsened from baseline (see Baseline Characteristics for ECOG Performance Status). (NCT00877006)
Timeframe: Week 32

,
Interventionparticipants (Number)
ImprovedStayed the SameWorsened
Bendamustine/Rituximab3215334
R-CHOP/R-CVP2814142

Number of Participants With Adverse Events (AEs), Serious Adverse Events (SAEs), Deaths and Discontinuations Due to AEs at End of Treatment Period

AE=any untoward medical occurrence that develops or worsens in severity after dispensation of the study drug and does not necessarily have a causal relationship to the study drug. An AE can, therefore, be any unfavorable and unintended physical sign, symptom, or laboratory parameter that develops or worsens in severity during the course of the study, or significant worsening of the disease under study (or any concurrent disease), whether or not considered related to the study drug. AEs were graded as 1 (mild), 2 (moderate), 3 (severe), 4 (life-threatening), 5 (death). SAE=an adverse event occurring at any dose that results in: death, a life-threatening adverse event, inpatient hospitalization or prolongation of existing hospitalization, a persistent or significant disability/incapacity (a substantial disruption of one's ability to conduct normal life functions), a congenital anomaly/birth defect, or other important medical event. (NCT00877006)
Timeframe: 32 weeks

,
Interventionparticipants (Number)
Any AESevere AEs (grades 3, 4, 5)Treatment-related AEsDeathsSAEsWithdrawn due to AEs
Bendamustine and Rituximab (BR)221130209126010
R-CHOP/R-CVP213127NA9493

Participants Who Died At the End of the Treatment Period or the Long-Term Follow-up Period

Death is due to any cause. Data are broken out by patients who died within 30 days of the last dose of study medications, and those who died greater than 30 days of the last dose of study medications. (NCT00877006)
Timeframe: Treatment Period: 18-32 weeks Long-Term Follow-up Period: up to 5 years after the Treatment Period

,
InterventionParticipants (Count of Participants)
All DeathsDeaths within 30 days of study treatmentDeaths greater than 30 days of study treatment
Bendamustine and Rituximab (BR)40238
R-CHOP/R-CVP32131

Potentially Clinically Significant Abnormal Weight

Participants were weighed at Baseline and at Endpoint (Week 32); those participants with an increase or decrease of >=10% were considered potentially clinically significant. (NCT00877006)
Timeframe: Baseline, Week 32

,
Interventionparticipants (Number)
Increase >=10%Decrease >=10%
Bendamustine and Rituximab (BR)818
R-CHOP/R-CVP58

Therapeutic Classification of Concomitant Medications

(NCT00877006)
Timeframe: 32 weeks

,
Interventionparticipants (Number)
PsycholepticsSex Hormones and Modulators of the Genital SystemStomatological PreparationsThroat PreparationsThyroid TherapyTopical Preparations for Join and Muscular PainUnspecified HerbalUrologicalsVaccinesVasoprotectivesVitamins
Bendamustine and Rituximab (BR)696233313511116
R-CHOP/R-CVP744292125411821

Therapeutic Classification of Prior Medications

(NCT00877006)
Timeframe: prior to start of treatment

,
Interventionparticipants (Number)
PsycholepticsSex Hormones and Modulators of the Genital SystemStomatological PreparationsThroat PreparationsThyroid TherapyTopical Products for Join and Muscular PainUnspecified HerbalUrologicalsVaccinesVasoprotectivesVitamins
Bendamustine and Rituximab (BR)57110016110202070
R-CHOP/R-CVP59120017010117061

Worst Overall Common Terminology Criteria for Adverse Events (CTCAE) Grades for Serum Chemistry Laboratory Test Results

Clinical laboratory data were graded according to National Cancer Institute's (NCI) CTCAE version 3, and graded as 1 (mild), 2 (moderate), 3 (severe), 4 (life-threatening), 5 (death). The table presents the worst CTCAE grades for serum chemistry test results experienced by participants overall (i.e., the worst post-baseline grade value for each participant and laboratory test across all cycles). (NCT00877006)
Timeframe: 32 weeks (conducted at screening, Day 1 of each cycle, and end-of-treatment visit)

,
Interventionparticipants (Number)
Albumin: Grade 1Albumin: Grade 2Albumin: Grade 3Albumin: Grade 4Albumin: Grades 1-4Alkaline Phosphatase: Grade 1Alkaline Phosphatase: Grade 2Alkaline Phosphatase: Grade 3Alkaline Phosphatase: Grade 4Alkaline Phosphatase: Grades 1-4Creatinine: Grade 1Creatinine: Grade 2Creatinine: Grade 3Creatinine: Grade 4Creatinine: Grades 1-4Gamma-glutamyl transferase: Grade 1Gamma-glutamyl transferase: Grade 2Gamma-glutamyl transferase: Grade 3Gamma-glutamyl transferase: Grade 4Gamma-glutamyl transferase: Grades 1-4Hypercalcemia: Grade 1Hypercalcemia: Grade 2Hypercalcemia: Grade 3Hypercalcemia: Grade 4Hypercalcemia: Grades 1-4Hyperglycemia: Grade 1Hyperglycemia: Grade 2Hyperglycemia: Grade 3Hyperglycemia: Grade 4Hyperglycemia: Grades 1-4Hyperkalemia: Grade 1Hyperkalemia: Grade 2Hyperkalemia: Grade 3Hyperkalemia: Grade 4Hyperkalemia: Grades 1-4Hypernatremia: Grade 1Hypernatremia: Grade 2Hypernatremia: Grade 3Hypernatremia: Grade 4Hypernatremia: Grades 1-4Hypocalcemia: Grade 1Hypocalcemia: Grade 2Hypocalcemia: Grade 3Hypocalcemia: Grade 4Hypocalcemia: Grades 1-4Hypoglycemia: Grade 1Hypoglycemia: Grade 2Hypoglycemia: Grade 3Hypoglycemia: Grade 4Hypoglycemia: Grades 1-4Hypokalemia: Grade 1Hypokalemia: Grade 2Hypokalemia: Grade 3Hypokalemia: Grade 4Hypokalemia: Grades 1-4Hyponatremia: Grade 1Hyponatremia: Grade 2Hyponatremia: Grade 3Hyponatremia: Grade 4Hyponatremia: Grades 1-4Magnesium: Grade 1Magnesium: Grade 2Magnesium: Grade 3Magnesium: Grade 4Magnesium: Grades 1-4Phosphorus: Grade 1Phosphorus: Grade 2Phosphorus: Grade 3Phosphorus: Grade 4Phosphorus: Grades 1-4Aspartate Aminotransferase: Grade 1Aspartate Aminotransferase: Grade 2Aspartate Aminotransferase: Grade 3Aspartate Aminotransferase: Grade 4Aspartate Aminotransferase: Grades 1-4Alanine Aminotransferase: Grade 1Alanine Aminotransferase: Grade 2Alanine Aminotransferase: Grade 3Alanine Aminotransferase: Grade 4Alanine Aminotransferase: Grades 1-4Total Bilirubin: Grade 1Total Bilirubin: Grade 2Total Bilirubin: Grade 3Total Bilirubin: Grade 4Total Bilirubin: Grades 1-4Uric Acid: Grade 1Uric Acid: Grade 2Uric Acid: Grade 3Uric Acid: Grade 4Uric Acid: Grades 1-4
Bendamustine and Rituximab (BR)331430504110042193102331183052601079420150129731011800083681348151001618000184000040460004672530354221045466205414100154100142
R-CHOP/R-CVP44130057253002825100263710605360006743415112481009100001028600341000010160101728050334411046522313132210353831042700074200042

Worst Overall CTCAE Grade for Hematology Laboratory Test Results

Hematology test data were graded according to National Cancer Institute's (NCI) CTCAE version 3, and graded as 1 (mild), 2 (moderate), 3 (severe), 4 (life-threatening), 5 (death). The table presents the worst CTCAE grades for hematology test results experienced by participants overall (i.e., the worst post-baseline grade value for each participant and hematology test across all cycles). (NCT00877006)
Timeframe: 32 weeks (conducted at screening, Day 1 of each cycle, weekly during treatment, and at the end-of-treatment visit)

,
Interventionparticipants (Number)
Absolute Neutrophil Count: Grade 1Absolute Neutrophil Count: Grade 2Absolute Neutrophil Count: Grade 3Absolute Neutrophil Count: Grade 4Absolute Neutrophil Count: Grades 1-4Hemoglobin: Grade 1Hemoglobin: Grade 2Hemoglobin: Grade 3Hemoglobin: Grade 4Hemoglobin: Grades 1-4Lymphocytes Absolute: Grade 1Lymphocytes Absolute: Grade 2Lymphocytes Absolute: Grade 3Lymphocytes Absolute: Grade 4Lymphocytes Absolute: Grades 1-4Platelets: Grade 1Platelets: Grade 2Platelets: Grade 3Platelets: Grade 4Platelets: Grades 1-4White Blood Cells: Grade 1White Blood Cells: Grade 2White Blood Cells: Grade 3White Blood Cells: Grade 4White Blood Cells: Grades 1-4
Bendamustine and Rituximab (BR)225148501711294251177155483143106149713641796519204
R-CHOP/R-CVP142047104185129517218965555912572147810122498927187

Reviews

3 reviews available for prednisone and Alopecia

ArticleYear
Complications of chemotherapy for prostate cancer.
    Seminars in urologic oncology, 2001, Volume: 19, Issue:3

    Topics: Adenocarcinoma; Alopecia; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Docetaxel; Ga

2001
[Disseminated lupus erythematosus: an analysis of organ involvement].
    Schweizerische medizinische Wochenschrift, 1978, Nov-18, Volume: 108, Issue:46

    Topics: Abortion, Spontaneous; Adolescent; Adult; Alopecia; Antibodies, Antinuclear; Arthritis, Rheumatoid;

1978
Current status of new agents.
    Cancer chemotherapy reports. Part 3, 1972, Volume: 3, Issue:1

    Topics: Alopecia; Animals; Antibiotics, Antineoplastic; Antineoplastic Agents; Azacitidine; Azaguanine; Carm

1972

Trials

11 trials available for prednisone and Alopecia

ArticleYear
Randomized trial of bendamustine-rituximab or R-CHOP/R-CVP in first-line treatment of indolent NHL or MCL: the BRIGHT study.
    Blood, 2014, May-08, Volume: 123, Issue:19

    Topics: Adult; Aged; Aged, 80 and over; Alopecia; Antibodies, Monoclonal, Murine-Derived; Antineoplastic Com

2014
Randomized trial of bendamustine-rituximab or R-CHOP/R-CVP in first-line treatment of indolent NHL or MCL: the BRIGHT study.
    Blood, 2014, May-08, Volume: 123, Issue:19

    Topics: Adult; Aged; Aged, 80 and over; Alopecia; Antibodies, Monoclonal, Murine-Derived; Antineoplastic Com

2014
Randomized trial of bendamustine-rituximab or R-CHOP/R-CVP in first-line treatment of indolent NHL or MCL: the BRIGHT study.
    Blood, 2014, May-08, Volume: 123, Issue:19

    Topics: Adult; Aged; Aged, 80 and over; Alopecia; Antibodies, Monoclonal, Murine-Derived; Antineoplastic Com

2014
Randomized trial of bendamustine-rituximab or R-CHOP/R-CVP in first-line treatment of indolent NHL or MCL: the BRIGHT study.
    Blood, 2014, May-08, Volume: 123, Issue:19

    Topics: Adult; Aged; Aged, 80 and over; Alopecia; Antibodies, Monoclonal, Murine-Derived; Antineoplastic Com

2014
Randomized trial of bendamustine-rituximab or R-CHOP/R-CVP in first-line treatment of indolent NHL or MCL: the BRIGHT study.
    Blood, 2014, May-08, Volume: 123, Issue:19

    Topics: Adult; Aged; Aged, 80 and over; Alopecia; Antibodies, Monoclonal, Murine-Derived; Antineoplastic Com

2014
Randomized trial of bendamustine-rituximab or R-CHOP/R-CVP in first-line treatment of indolent NHL or MCL: the BRIGHT study.
    Blood, 2014, May-08, Volume: 123, Issue:19

    Topics: Adult; Aged; Aged, 80 and over; Alopecia; Antibodies, Monoclonal, Murine-Derived; Antineoplastic Com

2014
Randomized trial of bendamustine-rituximab or R-CHOP/R-CVP in first-line treatment of indolent NHL or MCL: the BRIGHT study.
    Blood, 2014, May-08, Volume: 123, Issue:19

    Topics: Adult; Aged; Aged, 80 and over; Alopecia; Antibodies, Monoclonal, Murine-Derived; Antineoplastic Com

2014
Randomized trial of bendamustine-rituximab or R-CHOP/R-CVP in first-line treatment of indolent NHL or MCL: the BRIGHT study.
    Blood, 2014, May-08, Volume: 123, Issue:19

    Topics: Adult; Aged; Aged, 80 and over; Alopecia; Antibodies, Monoclonal, Murine-Derived; Antineoplastic Com

2014
Randomized trial of bendamustine-rituximab or R-CHOP/R-CVP in first-line treatment of indolent NHL or MCL: the BRIGHT study.
    Blood, 2014, May-08, Volume: 123, Issue:19

    Topics: Adult; Aged; Aged, 80 and over; Alopecia; Antibodies, Monoclonal, Murine-Derived; Antineoplastic Com

2014
Poor survival outcome of docetaxel every three weeks plus prednisone for treatment of patients with hormone-refractory metastatic prostate cancer.
    Hematology/oncology and stem cell therapy, 2010, Volume: 3, Issue:3

    Topics: Aged; Alopecia; Anemia; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protoc

2010
Treatment of membranous lupus nephritis with nephrotic syndrome by sequential immunosuppression.
    Lupus, 1999, Volume: 8, Issue:7

    Topics: Adult; Alopecia; Anti-Inflammatory Agents; Azathioprine; Cohort Studies; Cyclophosphamide; Drug Ther

1999
Multicenter, randomized comparative trial of fludarabine and the combination of cyclophosphamide-doxorubicin-prednisone in 92 patients with Waldenström macroglobulinemia in first relapse or with primary refractory disease.
    Blood, 2001, Nov-01, Volume: 98, Issue:9

    Topics: Adult; Aged; Alopecia; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Proto

2001
Treatment of intermediate- and high-grade non-Hodgkin's lymphoma using CEOP versus CNOP.
    European journal of haematology, 2002, Volume: 68, Issue:3

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Alopecia; Antineoplastic Combined Chemotherapy Protocols

2002
Combination chemotherapy and adriamycin in patients with advanced breast cancer. A Southwest Oncology Group study.
    Cancer, 1976, Volume: 38, Issue:1

    Topics: Alopecia; Antineoplastic Agents; Breast Neoplasms; Cyclophosphamide; Doxorubicin; Drug Evaluation; D

1976
Cyclophosphamide therapy for rheumatoid arthritis.
    Archives of internal medicine, 1975, Volume: 135, Issue:6

    Topics: Administration, Oral; Alopecia; Arthritis, Rheumatoid; Blood Sedimentation; Clinical Trials as Topic

1975
Prospective, controlled trial of cyclophosphamide therapy in children with nephrotic syndrome. Report of the International study of Kidney Disease in Children.
    Lancet (London, England), 1974, Aug-24, Volume: 2, Issue:7878

    Topics: Adolescent; Age Factors; Alopecia; Child; Child, Preschool; Cyclophosphamide; Cystitis; Drug Evaluat

1974
A controlled prospective study of cyclophosphamide in relapsing, corticosteroid-responsive, minimal-lesion nephrotic syndrome in childhood.
    The Journal of pediatrics, 1973, Volume: 82, Issue:4

    Topics: Adolescent; Alopecia; Child; Cyclophosphamide; Cystitis; Drug Synergism; Female; Humans; Hypercholes

1973
[A contribution of the treatment of alopecia totalis].
    Zeitschrift fur Haut- und Geschlechtskrankheiten, 1967, Jan-01, Volume: 42, Issue:1

    Topics: Adolescent; Adult; Alopecia; Child; Child, Preschool; Chloroquine; Clinical Trials as Topic; Female;

1967
Chemotherapy of acute leukemia in childhood. Comparison of cyclophosphamide and mercaptopurine.
    The New England journal of medicine, 1966, Sep-01, Volume: 275, Issue:9

    Topics: Adolescent; Alopecia; Child; Child, Preschool; Cyclophosphamide; Cystitis; Drug Synergism; Female; H

1966

Other Studies

77 other studies available for prednisone and Alopecia

ArticleYear
Analysis of the effect of R-CHOP regimen of pegylated liposomal doxorubicin on elderly patients with stage Ⅲ-Ⅳ diffuse large B-cell lymphoma.
    Pakistan journal of pharmaceutical sciences, 2021, Volume: 34, Issue:6(Special)

    Topics: Age Factors; Aged; Aged, 80 and over; Alopecia; Antineoplastic Combined Chemotherapy Protocols; Card

2021
[Analysis of clinical and imaging features of 6 cases of linear scleroderma en coup de sabre with central nervous system involvement in children].
    Zhonghua er ke za zhi = Chinese journal of pediatrics, 2022, Nov-02, Volume: 60, Issue:11

    Topics: Alopecia; Anticonvulsants; Brain; Calcinosis; Child; Drug Resistant Epilepsy; Encephalomalacia; Fema

2022
Erosive pustular dermatosis of the scalp.
    Dermatology online journal, 2020, Aug-15, Volume: 26, Issue:8

    Topics: Alopecia; Anti-Inflammatory Agents; Female; Humans; Meningeal Neoplasms; Meningioma; Middle Aged; Mo

2020
Primary gastric diffuse large B-cell lymphoma: The role of dose-dense chemotherapy.
    Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners, 2019, Volume: 25, Issue:7

    Topics: Adult; Alopecia; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Doxorubicin; Fema

2019
Histopathological insights into hair loss in Cronkhite-Canada syndrome: diffuse anagen-telogen conversion precedes clinical hair loss progression.
    The Australasian journal of dermatology, 2014, Volume: 55, Issue:2

    Topics: Alopecia; Antineoplastic Agents, Hormonal; Disease Progression; Female; Hair Follicle; Humans; Hypoa

2014
[Fluctuating nodules on the scalp of a child].
    Enfermedades infecciosas y microbiologia clinica, 2015, Volume: 33, Issue:10

    Topics: Alopecia; Antifungal Agents; Child; Griseofulvin; Humans; Hyphae; Male; Microsporum; Prednisone; Sta

2015
Efficacy and Safety of Methotrexate Combined with Low- to Moderate-Dose Corticosteroids for Severe Alopecia Areata.
    Dermatology (Basel, Switzerland), 2016, Volume: 232, Issue:2

    Topics: Adolescent; Adult; Alopecia; Alopecia Areata; Anti-Inflammatory Agents; Child; Dermatologic Agents;

2016
[Combined-modality therapy for 150 cases of early-stage Hodgkin's lymphoma].
    Zhonghua zhong liu za zhi [Chinese journal of oncology], 2008, Volume: 30, Issue:8

    Topics: Adolescent; Adult; Aged; Alopecia; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Child;

2008
[Satoyoshi syndrome: report of one case].
    Revista medica de Chile, 2009, Volume: 137, Issue:4

    Topics: Adolescent; Adrenal Cortex Hormones; Alopecia; Autoimmune Diseases; Carbamazepine; Diarrhea; Female;

2009
Graham-Little syndrome.
    Acta dermatovenerologica Alpina, Pannonica, et Adriatica, 2010, Volume: 19, Issue:3

    Topics: Alopecia; Female; Glucocorticoids; Humans; Keratosis; Middle Aged; Prednisone; Scalp; Scalp Dermatos

2010
Cutaneous CD8+ T-cell infiltrates associated with human immunodeficiency virus.
    Actas dermo-sifiliograficas, 2012, Volume: 103, Issue:7

    Topics: Adenine; Alopecia; Anti-HIV Agents; Antigens, Differentiation, T-Lymphocyte; Antiretroviral Therapy,

2012
[Rituximab as rescue therapy in refractory esophageal lichen planus].
    Gastroenterologia y hepatologia, 2013, Volume: 36, Issue:4

    Topics: Alopecia; Androstadienes; Anti-Inflammatory Agents; Antibodies, Monoclonal, Murine-Derived; Atrophy;

2013
Acute diffuse and total alopecia of the female scalp. A new subtype of diffuse alopecia areata that has a favorable prognosis.
    Dermatology (Basel, Switzerland), 2002, Volume: 205, Issue:4

    Topics: Acute Disease; Administration, Oral; Administration, Topical; Adult; Alopecia; Alopecia Areata; Biop

2002
Cicatricial alopecia due to sarcoidosis.
    Dermatology online journal, 2003, Volume: 9, Issue:1

    Topics: Administration, Oral; Adult; Alopecia; Biopsy; Cicatrix; Humans; Male; Prednisone; Sarcoidosis; Skin

2003
[Hair growth in alopecia gravis totalis after prednisone ointment].
    Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete, 1957, Volume: 8, Issue:5

    Topics: Alopecia; Alopecia Areata; Hair; Humans; Ointments; Prednisone

1957
[Treatment of alopecia areata with synthetic estrogens & prednisone].
    Dermatologische Wochenschrift, 1957, Oct-05, Volume: 136, Issue:40

    Topics: Alopecia; Alopecia Areata; Diethylstilbestrol; Estradiol Congeners; Humans; Prednisone

1957
[Results of treatment of advanced cases of alopecia areata with prednis one].
    Dermatologische Wochenschrift, 1961, Dec-02, Volume: 144

    Topics: Alopecia; Alopecia Areata; Humans; Prednisone

1961
[Critical contribution on steroid therapy of total baldness].
    Dermatologische Wochenschrift, 1961, Sep-02, Volume: 144

    Topics: Alopecia; Alopecia Areata; Humans; Prednisone

1961
ALOPECIA; TREATMENT WITH A LOCAL PSORALEN AND STEROID COMBINATION.
    Skin, 1963, Volume: 2

    Topics: Acetates; Adolescent; Alcohols; Alopecia; Child; Ethanol; Ficusin; Humans; Hydrocortisone; Irritants

1963
THREE CASES RESEMBLING POLYARTERITIS NODOSA ARISING DURING TREATMENT WITH GUANETHIDINE.
    British medical journal, 1964, Sep-05, Volume: 2, Issue:5409

    Topics: Alopecia; Chlorothiazide; Geriatrics; Guanethidine; Hypertension; Phenobarbital; Polyarteritis Nodos

1964
[RARE COMPLICATIONS OF INFECTIOUS MONONUCLEOSIS].
    La Presse medicale, 1964, Oct-10, Volume: 72

    Topics: Alopecia; Child; Chlortetracycline; Headache; Humans; Infectious Mononucleosis; Liver; Porphyrias; P

1964
ATROPHIC ALOPECIA DUE TO GRANULOMATOUS INFILTRATION OF SCALP IN SYSTEMIC SARCOIDOSIS.
    Proceedings of the Royal Society of Medicine, 1965, Volume: 58

    Topics: Alopecia; Diagnosis; Granuloma; Humans; Pathology; Prednisone; Sarcoidosis; Scalp

1965
Primary cutaneous follicle center cell lymphoma of the scalp successfully treated with anti CD20 monoclonal antibody and CHOP combination therapy with no subsequent permanent loss of hair.
    The Journal of dermatology, 2003, Volume: 30, Issue:9

    Topics: Adult; Alopecia; Antibodies, Monoclonal; Antibodies, Monoclonal, Murine-Derived; Antineoplastic Comb

2003
A case of Satoyoshi syndrome: a multisystem disorder.
    Clinical pediatrics, 2003, Volume: 42, Issue:8

    Topics: Adolescent; Alopecia; Glucocorticoids; Humans; Immunoglobulins, Intravenous; Male; Muscle Spasticity

2003
Vogt-Koyanagi-Harada syndrome and ulcerative colitis.
    Southern medical journal, 2004, Volume: 97, Issue:2

    Topics: Adult; Alopecia; Colitis, Ulcerative; Glucocorticoids; Humans; Male; Prednisone; Uveomeningoencephal

2004
Extensive annular verrucous late secondary syphilis.
    The British journal of dermatology, 2005, Volume: 152, Issue:6

    Topics: Adult; Alopecia; Drug Therapy, Combination; Glucocorticoids; Humans; Male; Penicillin G Benzathine;

2005
The use of methotrexate alone or in combination with low doses of oral corticosteroids in the treatment of alopecia totalis or universalis.
    Journal of the American Academy of Dermatology, 2006, Volume: 55, Issue:4

    Topics: Administration, Oral; Adult; Aged; Alopecia; Drug Therapy, Combination; Female; Glucocorticoids; Hum

2006
Corticosteroid-responsive Cronkhite-Canada syndrome complicated by thrombosis.
    Digestive diseases and sciences, 2007, Volume: 52, Issue:4

    Topics: Alopecia; Anticoagulants; Glucocorticoids; Humans; Hyperpigmentation; Intestinal Polyposis; Intestin

2007
[CEOP regimen in the treatment for non-Hodgkin's lymphoma].
    Zhonghua zhong liu za zhi [Chinese journal of oncology], 2007, Volume: 29, Issue:5

    Topics: Adolescent; Adult; Aged; Alopecia; Antineoplastic Combined Chemotherapy Protocols; Child; Combined M

2007
[Clinical aspects and therapy of anaplastic T-zone lymphoma].
    Deutsche medizinische Wochenschrift (1946), 1984, Jul-13, Volume: 109, Issue:28-29

    Topics: Alopecia; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cyclophosphamide; Doxorubicin;

1984
Adriamycin, dibromodulcitol, and mitomycin combination chemotherapy for patients with metastatic breast carcinoma previously treated with cyclophosphamide, methotrexate, 5-fluorouracil, vincristine, and prednisone.
    Cancer, 1984, May-01, Volume: 53, Issue:9

    Topics: Adult; Aged; Alopecia; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Breast Neopla

1984
Evaluation of the LSA2L2 protocol for treatment of childhood non-Hodgkin's lymphoma. A report from the Polish Children's Leukemia/Lymphoma Study Group.
    The American journal of pediatric hematology/oncology, 1984,Winter, Volume: 6, Issue:4

    Topics: Abdominal Neoplasms; Alopecia; Antineoplastic Combined Chemotherapy Protocols; Central Nervous Syste

1984
[Chemotherapy of metastasizing breast cancer. Adriamycin mono and combination therapy after LMFP pretreatment].
    Deutsche medizinische Wochenschrift (1946), 1983, Dec-02, Volume: 108, Issue:48

    Topics: Alopecia; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chlorambucil; Cyclophosp

1983
Prolonged remissions of metastatic breast cancer achieved with a six-drug regimen of relatively low toxicity.
    Cancer, 1983, Jun-01, Volume: 51, Issue:11

    Topics: Adult; Aged; Alopecia; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Breast

1983
VP-16 and adriamycin in patients with advanced breast cancer.
    American journal of clinical oncology, 1982, Volume: 5, Issue:5

    Topics: Adenocarcinoma; Adult; Aged; Alopecia; Antineoplastic Combined Chemotherapy Protocols; Breast Neopla

1982
Systemic lupus erythematosus: important considerations in the adolescent.
    Journal of adolescent health care : official publication of the Society for Adolescent Medicine, 1982, Volume: 2, Issue:4

    Topics: Adolescent; Alopecia; Anxiety; Chronic Disease; Depression; Female; Humans; Hydroxychloroquine; Lupu

1982
Vogt-Koyanagi-Harada syndrome in a 4-year old child.
    American journal of ophthalmology, 1995, Volume: 120, Issue:5

    Topics: Alopecia; Anti-Inflammatory Agents; Antineoplastic Agents, Alkylating; Blindness; Child, Preschool;

1995
Chronic cutaneous lupus erythematosus treated with thalidomide.
    Archives of dermatology, 1993, Volume: 129, Issue:12

    Topics: Adult; Alopecia; Female; Humans; Lupus Erythematosus, Discoid; Prednisone; Scalp Dermatoses; Thalido

1993
Postmenopausal frontal fibrosing alopecia: a frontal variant of lichen planopilaris.
    Journal of the American Academy of Dermatology, 1997, Volume: 36, Issue:1

    Topics: Administration, Oral; Aged; Aged, 80 and over; Alopecia; Antimalarials; Biopsy; Chloroquine; Dermato

1997
Radiological and orthopedic abnormalities in Satoyoshi syndrome.
    Pediatric radiology, 1997, Volume: 27, Issue:5

    Topics: Adult; Alopecia; Amenorrhea; Body Height; Bone and Bones; Bone Diseases, Developmental; Female; Frac

1997
Chronic inflammatory polyradiculoneuropathy associated with alopecia universalis.
    Muscle & nerve, 1998, Volume: 21, Issue:1

    Topics: Alopecia; Anti-Inflammatory Agents; Autoimmune Diseases; Chronic Disease; Electromyography; Humans;

1998
Cronkhite-Canada syndrome: report of two cases, biopsy findings in the associated alopecia, and a new treatment option.
    Cutis, 1998, Volume: 61, Issue:4

    Topics: Aged; Alopecia; Female; Glucocorticoids; Humans; Intestinal Polyps; Nail Diseases; Prednisone; Ranit

1998
Systemic polychemotherapy in the treatment of primary cutaneous lymphomas: a clinical follow-up study of 81 patients treated with COP or CHOP.
    Leukemia & lymphoma, 1998, Volume: 31, Issue:5-6

    Topics: Adult; Aged; Aged, 80 and over; Alopecia; Antineoplastic Combined Chemotherapy Protocols; Bone Marro

1998
2-Chlorodeoxyadenosine (Cladribine) in the treatment of patients with chronic lymphocytic leukemia 55 years old and younger.
    Leukemia, 1999, Volume: 13, Issue:4

    Topics: Adult; Alopecia; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Ch

1999
Association between alopecia and response to aggressive chemotherapy in patients with Hodgkin's disease.
    Medical hypotheses, 1999, Volume: 53, Issue:5

    Topics: Adult; Alopecia; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Dacarbazine; Doxorubicin

1999
Aching alopecia.
    Lancet (London, England), 2002, Apr-06, Volume: 359, Issue:9313

    Topics: Aged; Alopecia; Female; Giant Cell Arteritis; Glucocorticoids; Humans; Prednisone

2002
Alopecia in Wegener's granulomatosis.
    Annals of the rheumatic diseases, 2002, Volume: 61, Issue:7

    Topics: Alopecia; Cyclophosphamide; Female; Glucocorticoids; Granulomatosis with Polyangiitis; Humans; Immun

2002
Combination chemotherapy ("CHOP-Bleo") in advanced (non-Hodgkin) malignant lymphoma.
    Blood, 1977, Volume: 49, Issue:3

    Topics: Adult; Aged; Alopecia; Bleomycin; Bone Marrow; Cell Transformation, Neoplastic; Cyclophosphamide; Do

1977
Corticosteroids in the treatment of alopecia totalis. Systemic effects.
    Archives of dermatology, 1978, Volume: 114, Issue:10

    Topics: Administration, Oral; Administration, Topical; Adolescent; Adrenal Cortex Hormones; Adult; Alopecia;

1978
Combinaed chemotherapy with cyclophosphamide, vinblastine, procarbazine, and prednisone (CVPP) for patients with advanced Hodgkin's disease. An alternative program to MOPP.
    Cancer, 1976, Volume: 38, Issue:1

    Topics: Adolescent; Adult; Age Factors; Aged; Alopecia; Antineoplastic Agents; Cyclophosphamide; Drug Therap

1976
Combination chemotherapy in the treatment of advanced breast cancer.
    Journal of surgical oncology, 1976, Volume: 8, Issue:6

    Topics: Adrenalectomy; Alopecia; Antineoplastic Agents; Breast Neoplasms; Cyclophosphamide; Drug Therapy, Co

1976
["Preventive" cranial irradiation in acute lymphoblastic leukemia in childhood].
    Strahlentherapie, 1976, Volume: 151, Issue:1

    Topics: Acute Disease; Adolescent; Age Factors; Alopecia; Brain Neoplasms; Child; Child, Preschool; Cyclopho

1976
Toxicity and side-effects of combination chemohormonal therapy of advanced breast cancer.
    Journal of the Indian Medical Association, 1992, Volume: 90, Issue:2

    Topics: Alopecia; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Combined Modality Therap

1992
The diagnostic features of SLE.
    Hospital practice (Office ed.), 1989, Jan-30, Volume: 24, Issue:1A

    Topics: Adult; Alopecia; Blood Chemical Analysis; Exanthema; Female; Humans; Lupus Erythematosus, Systemic;

1989
Erythroderma with spongiotic dermatitis. Association with common variable hypogammaglobulinemia.
    The American journal of medicine, 1985, Volume: 78, Issue:3

    Topics: Agammaglobulinemia; Aged; Alopecia; B-Lymphocytes; Dermatitis; Dermatitis, Exfoliative; Edema; Human

1985
Methylprednisolone, etoposide, vindesine, and chlorambucil (PEEC) alone or alternating with CHOP as initial or salvage therapy for non-Hodgkin's lymphoma.
    Scottish medical journal, 1988, Volume: 33, Issue:6

    Topics: Adult; Aged; Alopecia; Antineoplastic Combined Chemotherapy Protocols; Chlorambucil; Cyclophosphamid

1988
[Chronic discoid lupus erythematosus; who is afraid of the red wolf?].
    Nederlands tijdschrift voor geneeskunde, 1985, Apr-27, Volume: 129, Issue:17

    Topics: Adult; Alopecia; Antimalarials; Azathioprine; Facial Dermatoses; Female; Glossitis; Humans; Lupus Er

1985
Long-term assessment of cyclophosphamide therapy for nephrosis in children.
    Lancet (London, England), 1974, Oct-26, Volume: 2, Issue:7887

    Topics: Adolescent; Age Factors; Alopecia; Azathioprine; Child; Child, Preschool; Cyclophosphamide; Cystitis

1974
[A clinical contribution on idiopathic follicular mucinosis (alopecia mucinosa H. Pinkus)].
    Zeitschrift fur Haut- und Geschlechtskrankheiten, 1967, Jan-01, Volume: 42, Issue:1

    Topics: Adolescent; Alopecia; Climate; Humans; Hyaluronoglucosaminidase; Male; Mucinosis, Follicular; Penici

1967
[Follicular mucinosis].
    Dermatologische Wochenschrift, 1968, Mar-09, Volume: 154, Issue:10

    Topics: Alopecia; Humans; Male; Middle Aged; Mucinosis, Follicular; Prednisone; Skin; Skin Diseases

1968
Cutaneous complications in immunosuppressed renal homograft recipients.
    JAMA, 1974, Jul-22, Volume: 229, Issue:4

    Topics: Acne Vulgaris; Adolescent; Adult; Alopecia; Azathioprine; Carcinoma, Basal Cell; Carcinoma, Squamous

1974
Letter: Treatment of alopecia totalis.
    JAMA, 1974, Nov-04, Volume: 230, Issue:5

    Topics: Alopecia; Humans; Prednisone

1974
Blood and neoplastic diseases. Treatment of the lymphomas.
    British medical journal, 1974, Dec-28, Volume: 4, Issue:5947

    Topics: Alopecia; Bone Marrow; Cyclophosphamide; Hodgkin Disease; Humans; Lymphoma; Lymphoma, Follicular; Ne

1974
Cyclophosphamide in the treatment of pemphigus vulgaris and bullous pemphigoid.
    Archives of dermatology, 1972, Volume: 106, Issue:5

    Topics: Adult; Aged; Alopecia; Cataract; Child; Cyclophosphamide; Diabetes Mellitus; Female; Humans; Leukope

1972
Systemic corticosteroids in alopecia totalis.
    Canadian Medical Association journal, 1973, Jan-20, Volume: 108, Issue:2

    Topics: Adolescent; Alopecia; Female; Glucocorticoids; Humans; Injections, Intradermal; Male; Middle Aged; P

1973
Treatment of patients with systemic lupus erythematosus including nephritis with chlorambucil.
    British medical journal, 1973, Apr-28, Volume: 2, Issue:5860

    Topics: Adult; Alopecia; Amenorrhea; Azathioprine; Biopsy; Bone Marrow; Chlorambucil; Cyclophosphamide; Cyst

1973
A phase 2 evaluation of 1-(2-chloroethyl)-3-(4- methylcyclohexyl)-1-nitrosourea (NSC 95441) in patients with advanced breast cancer.
    Cancer research, 1974, Volume: 34, Issue:1

    Topics: Alopecia; Blood Platelets; Breast Neoplasms; Castration; Cyclohexanes; Cyclophosphamide; Drug Evalua

1974
Concurrent chemotherapy and radiation therapy in the treatment of childhood and adolescent Hodgkin's disease.
    Cancer, 1974, Volume: 33, Issue:1

    Topics: Adolescent; Adult; Age Factors; Alopecia; Child; Child, Preschool; Cobalt Radioisotopes; Cyclophosph

1974
Cyclical combination chemotherapy for advanced breast carcinoma.
    British medical journal, 1974, Feb-09, Volume: 1, Issue:5901

    Topics: Adrenalectomy; Adult; Alopecia; Bone Marrow; Bone Neoplasms; Breast Neoplasms; Castration; Cyclophos

1974
Protection from chemotherapeutic epilation by prior irradiation.
    Radiology, 1974, Volume: 112, Issue:1

    Topics: Adolescent; Alopecia; Antineoplastic Agents; Child; Cyclophosphamide; Drug Therapy, Combination; Fem

1974
Toxicity studies of fluorouracil used with adrenalectomy in breast cancer.
    Archives of surgery (Chicago, Ill. : 1960), 1972, Volume: 105, Issue:1

    Topics: Adrenalectomy; Adult; Aged; Alopecia; Ataxia; Blood Platelet Disorders; Breast Neoplasms; Diarrhea;

1972
Cicatricial pemphigoid.
    Archives of dermatology, 1971, Volume: 104, Issue:4

    Topics: Aged; Alopecia; Female; Humans; Methotrexate; Prednisone; Skin Diseases

1971
Vincristine and prednisone for the induction of remissions in acute childhood leukaemia.
    British medical journal, 1969, Jun-14, Volume: 2, Issue:5658

    Topics: Acute Disease; Alopecia; Child; Child, Preschool; Drug Synergism; Gastrointestinal Diseases; Humans;

1969
[Weight changes in children treated with corticoids].
    Ceskoslovenska pediatrie, 1967, Volume: 22, Issue:12

    Topics: Adolescent; Adrenal Cortex Hormones; Adult; Alopecia; Body Weight; Child; Dexamethasone; Female; Hum

1967
Cyclophosphamide in the nephrotic syndrome of childhood: its use in two groups of patients defined by clinical, light microscopic and immunopathologic findings.
    Canadian Medical Association journal, 1968, Mar-16, Volume: 98, Issue:11

    Topics: Alopecia; Biopsy; Blood Cell Count; Child; Child, Preschool; Cyclophosphamide; Female; Humans; Male;

1968
[Combined treatment of patients with alopecia areata and total alopecia by using corticosteroid drugs orally and topically].
    Vestnik dermatologii i venerologii, 1965, Volume: 39, Issue:11

    Topics: Alopecia; Alopecia Areata; Anti-Inflammatory Agents; Humans; Prednisolone; Prednisone

1965
[Hair melanogenesis in endoxan alopecia and its modification by corticosteroids].
    Archiv fur klinische und experimentelle Dermatologie, 1966, Sep-14, Volume: 226, Issue:1

    Topics: Alopecia; Breast Neoplasms; Cyclophosphamide; Female; Hair; Humans; Male; Melanins; Neoplasms; Predn

1966