prednisone has been researched along with Alloxan Diabetes in 12 studies
Prednisone: A synthetic anti-inflammatory glucocorticoid derived from CORTISONE. It is biologically inert and converted to PREDNISOLONE in the liver.
prednisone : A synthetic glucocorticoid drug that is particularly effective as an immunosuppressant, and affects virtually all of the immune system. Prednisone is a prodrug that is converted by the liver into prednisolone (a beta-hydroxy group instead of the oxo group at position 11), which is the active drug and also a steroid.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Troglitazone (TGZ) treatment, beginning at 6 weeks of age, prevented the hyperglycemia, the hyperlipidemia, and the increase in 11beta-HSD-1." | 1.32 | Increased expression and activity of 11beta-HSD-1 in diabetic islets and prevention with troglitazone. ( Agarwal, AK; Duplomb, L; Lee, Y; Park, BH; Takaishi, K; Unger, RH; Wang, MY, 2004) |
| "Hyperglycemia has been linked to increased oxidative stress, leading to endothelial dysfunction, delayed cell replication, and enhanced apoptosis." | 1.32 | Heme oxygenase-1 prevents superoxide anion-associated endothelial cell sloughing in diabetic rats. ( Abraham, NG; Goodman, AI; Ikehara, S; Inaba, M; Kaminski, PM; Morita, T; Quan, S; Wolin, MS; Yang, L, 2004) |
| "Prednisone-treated dogs were hyperglycemic during treatment but returned to normoglycemia after steroid withdrawal." | 1.29 | Acceleration of chronic failure of intrahepatic canine islet autografts by a short course of prednisone. ( Carroll, PB; Demetris, J; Fontes, P; Ricordi, C; Rilo, HL; Zeng, YJ, 1994) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (50.00) | 18.7374 |
| 1990's | 2 (16.67) | 18.2507 |
| 2000's | 2 (16.67) | 29.6817 |
| 2010's | 1 (8.33) | 24.3611 |
| 2020's | 1 (8.33) | 2.80 |
| Authors | Studies |
|---|---|
| Machado, MPR | 1 |
| Schavinski, AZ | 1 |
| Deluque, AL | 1 |
| Volpato, GT | 1 |
| Campos, KE | 1 |
| Zhao, L | 1 |
| Pan, Y | 1 |
| Peng, K | 1 |
| Wang, Z | 1 |
| Li, J | 1 |
| Li, D | 1 |
| Tong, C | 1 |
| Wang, Y | 1 |
| Liang, G | 1 |
| CARDEZA, AF | 2 |
| PENHOS, JC | 2 |
| Duplomb, L | 1 |
| Lee, Y | 1 |
| Wang, MY | 1 |
| Park, BH | 1 |
| Takaishi, K | 1 |
| Agarwal, AK | 1 |
| Unger, RH | 1 |
| Quan, S | 1 |
| Kaminski, PM | 1 |
| Yang, L | 1 |
| Morita, T | 1 |
| Inaba, M | 1 |
| Ikehara, S | 1 |
| Goodman, AI | 1 |
| Wolin, MS | 1 |
| Abraham, NG | 1 |
| Galluzzo, A | 1 |
| Rilo, HL | 1 |
| Carroll, PB | 1 |
| Zeng, YJ | 1 |
| Fontes, P | 1 |
| Demetris, J | 1 |
| Ricordi, C | 1 |
| Santini, A | 1 |
| Riccipetitoni, G | 1 |
| Morsiani, E | 1 |
| Durante, E | 1 |
| Genes, SG | 1 |
| Atef, M | 1 |
| Hanafy, MS | 1 |
| Arbid, MS | 1 |
| Leonard, DK | 1 |
| Landry, AS | 1 |
| Sollinger, HW | 1 |
| Hullett, DA | 1 |
| Scharp, DW | 1 |
| Alderson, D | 1 |
| Kneteman, NM | 1 |
1 review available for prednisone and Alloxan Diabetes
| Article | Year |
|---|---|
[Immunotherapy in type 1 (insulin-dependent) diabetes].
Topics: Animals; Bone Marrow Transplantation; Child; Cyclosporins; Diabetes Mellitus, Experimental; Diabetes | 1984 |
11 other studies available for prednisone and Alloxan Diabetes
| Article | Year |
|---|---|
The Treatment of Prednisone in Mild Diabetic Rats: Biochemical Parameters and Cell Response.
Topics: Animals; Blood Glucose; Body Weight; Diabetes Mellitus, Experimental; Glucocorticoids; Glucose Intol | 2020 |
Inhibition of 11β-HSD1 by LG13 improves glucose metabolism in type 2 diabetic mice.
Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 1; Animals; Blood Glucose; Cell Line; Curcumin; Dexamethas | 2015 |
Diabetogenic action of prednisone and prednisolone in dogs and rats.
Topics: Animals; Diabetes Mellitus, Experimental; Prednisolone; Prednisone | 1956 |
Diabetogenic action of prednisone and prednisolone in dogs and rats.
Topics: Animals; Diabetes Mellitus, Experimental; Prednisolone; Prednisone | 1956 |
Diabetogenic action of prednisone and prednisolone in dogs and rats.
Topics: Animals; Diabetes Mellitus, Experimental; Prednisolone; Prednisone | 1956 |
Diabetogenic action of prednisone and prednisolone in dogs and rats.
Topics: Animals; Diabetes Mellitus, Experimental; Prednisolone; Prednisone | 1956 |
Increased expression and activity of 11beta-HSD-1 in diabetic islets and prevention with troglitazone.
Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 1; Animals; Animals, Genetically Modified; Blotting, Weste | 2004 |
Heme oxygenase-1 prevents superoxide anion-associated endothelial cell sloughing in diabetic rats.
Topics: Animals; Anions; Antineoplastic Combined Chemotherapy Protocols; Aorta; Apoptosis; Bilirubin; Blotti | 2004 |
Acceleration of chronic failure of intrahepatic canine islet autografts by a short course of prednisone.
Topics: Animals; Blood Glucose; Chronic Disease; Diabetes Mellitus, Experimental; Dogs; Female; Graft Reject | 1994 |
[Current status on transplantation of the endocrine pancreas in the treatment of diabetes mellitus. I. Transplantation of the islands of Langerhans].
Topics: Animals; Child; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Dogs; Globulins; Guinea | 1979 |
[Corticosteroids and the liver].
Topics: Adrenal Cortex; Adrenal Cortex Hormones; Animals; Biotransformation; Diabetes Mellitus, Experimental | 1977 |
Enhanced diabetogenic effects of combined treatment with hydrochlorothiazide and prednisone in adjuvant arthritic rats.
Topics: Alanine Transaminase; Animals; Anti-Inflammatory Agents; Arthritis, Experimental; Blood Glucose; Blo | 1991 |
Prednisone, azathioprine, and cyclosporine A toxicity on human fetal pancreas.
Topics: Animals; Azathioprine; Culture Techniques; Cyclosporins; Diabetes Mellitus, Experimental; Fetus; Hum | 1989 |
The effects of immunosuppression on islet transplant function in the dog.
Topics: Animals; Azathioprine; Cyclosporins; Diabetes Mellitus, Experimental; Dogs; Immunosuppression Therap | 1987 |